Research Foundation Of The City University Of New York

FORMER WORKER SURVEILLANCE PROGRAM

CCNY/MSK CANCER CENTER PARTNERSHIP, TRAINING AND COMMUNITY OUTREACH

F0RMER WORKER SURVEILLANCE PROGRAM

CSC-EARTH SYSTEM SCIENCES AND REMOTE SENSING TECHNOLOGIES - ESSRST

TRADE ADJUSTMENT ASSISTANCE COMMUNITY COLLEGE AND CAREER TRAINING

THE NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION (NOAA) AWARD RECIPIENT IS THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK - THE CITY COLLEGE. THIS COOPERATIVE SCIENCE CENTER (CSC), FUNDED THROUGH NOAA OFFICE OF EDUCATION, EDUCATIONAL PARTNERSHIP PROGRAM WITH MINORITY SERVING INSTITUTIONS (EPP/MSI) IS FOCUSED ON EARTH SYSTEMS SCIENCE AND REMOTE SENSING TECHNOLOGIES ALIGNED WITH THE NOAA MISSION. THE ACADEMIC HOME OF THE CENTER IS THE GROVE SCHOOL OF ENGINEERING AT THE CITY COLLEGE OF NEW YORK. THIS IS THE SECOND FIVE-YEAR AWARD CYCLE FOR THE NOAA CENTER FOR EARTH SYSTEM SCIENCE AND REMOTE SENSING TECHNOLOGIES 9CESSRST-II). THE PURPOSE OF THIS EPP/MSI CSC AWARD IS TO ENHANCE DEVELOPING STUDENTS THROUGH EDUCATION, AND WITH INTERNSHIPS AT NOAA, TO BE A DIVERSE CADRE OF NEW PROFESSIONALS, REPRESENTATIVE OF THE NATION'S DEMOGRAPHY, AND ELIGIBLE CANDIDATES FOR THE FUTURE NOAA MISSION ENTERPRISE WORKFORCE. CESSRST-II IS TO BE FUNDED ANNUALLY, BASED ON SATISFACTORY PERFOR

RISE PROGRAM-HUNTER COLLEGE

NSF I-CORPS HUB: NEW YORK REGION

BASIC AND TRANSLATIONAL RESEARCH CENTER FOR REDUCING HEALTH DISPARITIES

NOAA-COOPERATIVE REMOTE SENSING SCIENCE AND TECHNOLOGY (CREST) CENTER

GAINING EARLY AWARENESS AND READINESS FOR UNDERGRADUATE PROGRAMS (GEAR UP PARTNERSHIP)

HEALTH PROFESSIONS OPPORTUNITY GRANTS- HOSOTOS COMMUNITY COLLEGE'S ALLIED HEALTH CAREER PIPELINE PROGRAM TO SERVE TANF RECIPIENTS AND LOW-INCOME INDI

RESEARCH CENTER FOR STUDY OF GENE STRUCTURE AND FUNCTION

GEAR-UP

GEAR-UP

NYCENTER FOR MINORITY HEALTH, EQUITY AND SOCIAL JUSTICE - OVERALL-ABSTRACT THE OVERALL GOAL OF THE NEW RCMI AT THE CITY COLLEGE OF NEW YORK (CCNY) IS TO CREATE AN INTEGRATED MULTI-TIERED CENTER, THE NYCENTER FOR MINORITY HEALTH, EQUITY, AND SOCIAL JUSTICE (NYC-MHESJ). THIS PROPOSAL IS FOUNDED ON THE HISTORIC COMMITMENT OF CUNY MED AND CCNY TO THE HARLEM COMMUNITY. LOCATED IN HARLEM AND LED BY THE CUNY MED, THE NEW RCMI COLLABORATES WITH CCNY’S DIVISION OF SCIENCE, THE COLIN POWELL SCHOOL FOR CIVIC & GLOBAL LEADERSHIP, AND THE GROVE SCHOOL OF ENGINEERING. IT SPANS BASIC BIOMEDICAL, BEHAVIORAL, SOCIAL SCIENCE, AND CLINICAL RESEARCH. IT FURTHER DEVELOPS AND STRENGTHENS RESEARCH INFRASTRUCTURE, IMPROVES THE QUALITY OF SCIENCE, AND ENHANCES THE PREPARATION AND CAPACITY OF EARLY-STAGE INVESTIGATORS (ESI) TO CONDUCT STATE-OF-THE-ART HEALTH DISPARITIES RESEARCH WHILE, CREATING STRATEGIC COMMUNICATIONS, AND IMPLEMENTING A DISSEMINATION PLAN FOCUSED ON UNDERSERVED NYC COMMUNITIES WHERE DEEP DISPARITIES EXIST AND PERSIST. THE SPECIFIC AIMS AND KEY ACTIVITIES FOR THE OVERALL CORE ARE TO: AIM-1 SUPPORT THREE OUTSTANDING R01-LEVEL RESEARCH PROJECTS CENTERED ON HEALTH DISPARITIES: • A BASIC SCIENCE PROPOSAL FOCUSED ON END-STAGE KIDNEY DISEASE, WHICH PREDOMINANTLY AFFECTS MINORITY POPULATIONS SUCH AS AFRICAN-AMERICANS AND LATINO(S); • A BEHAVIORAL SCIENCE PROJECT FOCUSED ON MENTAL HEALTH AND STIGMA IN ADOLESCENTS • A CLINICAL PROJECT FOCUSED ON UNDERSTANDING CLINICAL TRIAL PARTICIPATION AND RECRUITMENT PARAMETERS OF HISPANICS WITH PARKINSON’S DISEASE AIM-2 CREATE A RESEARCH CAPACITY CORE (RCC) TO STRENGTHEN CUNY MED AND CCNY’S RESEARCH CAPACITY BY EXPANDING ACCESS AND TRAINING IN MOLECULAR BIOLOGY/GENOMICS TECHNOLOGIES, ACCESS TO A BIOSTATISTICS, EPIDEMIOLOGY, AND RESEARCH DESIGN CORE, ARTIFICIAL INTELLIGENCE (AI), AND DATA AND COMPUTATIONAL SCIENCE TO STUDY HEALTH DISPARITIES. AIM-3 CREATE AND ADMINISTER AN INVESTIGATOR DEVELOPMENT CORE (IDC) LED BY EXPERIENCED MENTORS TO DEVELOP FACULTY, AWARD PILOT PROJECTS, AND ENHANCE TRAINING ACTIVITIES FOR UNDERREPRESENTED ESI AND FACULTY WITHIN AN EFFECTIVE INTEGRATED MENTORING PROGRAM. AIM-4 CREATE A COMMUNITY ENGAGEMENT CORE (CEC) FOCUSED ON MINORITY HEALTH AND HEALTH DISPARITES (HD) IN UNDERSERVED NYC COMMUNITIES. AIM-5 CREATE A RECRUITMENT CORE (RC) TO INCREASE THE CRITICAL MASS OF SENIOR-LEVEL HEALTH DISPARITIES INVESTIGATORS. AIM-6 DEVELOP AN ADMINISTRATIVE CORE (AC) THAT INTEGRATES AND ALIGNS INSTITUTIONAL AND CENTER GOALS AND EVALUATES AND SUPPORTS THE CENTER’S SCIENTIFIC ADVANCEMENT.

CELLULAR/MOLECULAR BASIS OF DEVELOPMENT: RESEARCH CENTER

ENVIRONMENTAL BIOSENSORS IN THE OLIGODENDROCYTE LINEAGE

CELLULAR/MOLECULAR BASIS OF DEVELOPMENT: RESEARCH CENTER

BRONX GEAR UP THRIVES -TURNING HIGHER [EDUCATION] RESOURCES INTO VITAL EXPERIENCES FOR STUDENTS

(2/2) TUFCCC/HC REGIONAL COMPREHENSIVE CANCER HEALTH DISPARITY PARTNERSHIP

BP-ENDURE AT HUNTER

RECOVERY ACT

QUEENS GROUND ZERO WORKERS HEALTH WATCH

OPTIMIZING HIV PREVENTION FOR HIGHLY VULNERABLE METHAMPHETAMINE-USING SEXUAL MINORITY MEN - SUMMARY THIS LITE-2 (RFA-AI-21-018) INITIATIVE RESPONDS TO A RESURGENT EPIDEMIC OF METHAMPHETAMINE (METH) USE IN SEXUAL MINORITY MEN (SMM), WHICH IS A PRIMARY DRIVER OF HIV INCIDENCE. THE OVERARCHING GOALS ARE TWO-FOLD: 1) IDENTIFY MULTI-LEVEL AND BIO-BEHAVIORAL DETERMINANTS OF AMPLIFIED HIV SEROCONVERSION RISK IN METH-USING SMM; AND 2) TEST THE EFFECTIVENESS OF TELEHEALTH MOTIVATIONAL ENHANCEMENT INTERVENTIONS FOR OPTIMIZING ENTRY OR RE-ENTRY OF SMM WHO USE METH INTO THE PREP CARE CONTINUUM. FINDINGS FROM OUR LITE-1 COHORT (UG3/UH3 AI-133675, RFA-AI-16-031) AND OTHERS PROVIDE COMPELLING EVIDENCE THAT METH USE IS INCREASING, DISPROPORTIONALLY IMPACTS RACIAL/ETHNIC MINORITIES, AND ACCOUNTS FOR ONE-IN-THREE NEW HIV INFECTIONS IN SMM. IN RESPONSE TO LITE-2 (RFA- AI-21-018) WE PROPOSE A MULTI-COMPONENT INITIATIVE ZEROING IN ON THE “WHERE,” “HOW,” AND “WHY” OF METH USE AND HIV RISK. WHERE: WHAT ARE THE GEOSPATIAL DETERMINANTS OF THE ASSOCIATION OF METH USE WITH HIV INCIDENCE? HOW: HOW CAN WE SUPPORT (RE-)ENTRY INTO THE PREP CARE CONTINUUM WITH THIS HIGH PRIORITY POPULATION OF SMM WHO USE METH? WHY: DOES METH AMPLIFY BIOLOGICAL RISK OF HIV BY POTENTIATING RECTAL IMMUNE DYSREGULATION? AIM 1: EXAMINE MULTI-LEVEL STRUCTURAL, PSYCHOLOGICAL, AND SOCIAL DETERMINANTS OF AMPLIFIED HIV SEROCONVERSION RISK IN SMM WHO USE METH. THE CENTERPIECE OF OUR LITE-2 INITIATIVE IS A NEW PROSPECTIVE, BIO-BEHAVIORAL COHORT WITH N=5,000 SMM (N=3,000 SMM WHO USE METH, N=2,000 WHO DO NOT). PARTICIPANTS WILL COMPLETE ASSESSMENTS OVER 36 MONTHS AND PROVIDE BIOLOGICAL SAMPLES FOR HIV TESTING, DRUG TOXICOLOGY TESTING, RECTAL STIS, AND RECTAL CYTOKINES/CHEMOKINES. OUR PRIMARY GOAL WILL BE TO INVESTIGATE THE ROLE OF GEOSPATIAL DETERMINANTS (E.G., BACKGROUND METH AND HIV PREVALENCE, URBANICITY) AND OTHER STRUCTURAL DETERMINANTS (E.G., STRUCTURAL STIGMA OF SEXUAL MINORITIES AS EVIDENCED BY POLICIES/LAWS) IN RELATION TO THE ASSOCIATION OF METH USE WITH AMPLIFIED HIV SEROCONVERSION RISK. AIM 2: TEST THE COMPARATIVE AND COMBINED EFFECTIVENESS OF TELEHEALTH MOTIVATIONAL ENHANCEMENT INTERVENTIONS FOR OPTIMIZING PREP USE. PREP READINESS INTERVENTIONS FOR SUPPORTING MOTIVATION (PRISM) IS A HYBRID TYPE I, MODIFIED FACTORIAL RANDOMIZED CONTROLLED TRIAL (RCT) OF TELEHEALTH CM THAT PROVIDES INCENTIVES FOR FILLING A PREP PRESCRIPTION, AND A 2-SESSION TELEHEALTH MI INTERVENTION THAT WE ADAPTED WITH METH- USING SMM (R34-DA046367, CARRICO/GROV). PRISM WILL ENROLL 840 METH-USING SMM WHO ARE NOT CURRENTLY TAKING PREP FROM THE LITE-2 COHORT (AIM 1) TO EXAMINE THE EFFECTIVENESS OF CM (N = 280), MI (N = 280), AND MI+CM (N = 280) ON THE PRIMARY OUTCOME – FILLING A PREP PRESCRIPTION. AIM 3: DETERMINE WHETHER GREATER RECTAL IMMUNE DYSREGULATION PARTIALLY EXPLAINS AMPLIFIED RISK OF HIV SEROCONVERSION IN SMM WHO USE METH. USING A CASE-COHORT DESIGN, WE WILL COMPARE HIV SEROCONVERTERS (N=450) WITH MATCHED SERONEGATIVE CONTROLS (N=450) TO EXAMINE THE CLINICAL RELEVANCE OF METH-INDUCED ALTERATIONS IN RECTAL CYTOKINES WITH RESPECT TO HIV SEROCONVERSION. THIS LITE-2 INITIATIVE COULD HAVE AN EXCEPTIONAL IMPACT BY TRANSFORMING HIV PREVENTION WITH SMM.

UNIVERSITY TRANSPORTATION CENTER

NRC FOR PERMANENCY AND FAMILY CONNECTIONS

MATHEMATICS AND SCIENCE TEACHER EDUCATION RESIDENCY

TAS::57 3600::TAS 'MAGNET-FREE NON-RECIPROCAL METAMATERIALS BASED ON SPATIO-TEMPORAL MODULATION,'

UNIVERSITY TRANPORTATION CENTER - PLANNING AND MANAGEMENT OF REGIONAL TRANSPORTATION SYSTEMS

CHILD MALTREATMENT AND RISK FOR MILD COGNITIVE IMPAIRMENT AND ALZHEIMER'S DISEASE

HEALTH PROFESSION OPPORTUNITY GRANTS TO SERVE TANF RECIPIENTS: ALLIED HEALTH CAREER PIPELI

COHORT LEARNING PROGRAM

CHASING COVID COHORT

CANCER GENOMICS:INTEGRATIVE AND SCALABLE SOLUTIONS IN R / BIOCONDUCTOR

MSPINNYC2 -- A NEW PARTNERSHIP TO TRANSFORM URBAN SECONDARY SCHOOL MATHEMATICS AND SCIENCE EXPERIENCES

UNIVERSITY TRANSPORTATION CENTER

COMMUNITY-ENGAGED INTERVENTION TO OPTIMIZE THE IMPACT OF RENOVATEDNEIGHBORHOOD PARKS ON COMMUNITY WELLBEING - PROJECT SUMMARY PARKS ARE A KEY FEATURE OF THE BUILT ENVIRONMENT THAT FOSTER COMMUNITY ENGAGEMENT, MAKE COMMUNITIES VIBRANT, AND SUPPORT RESIDENT WELLBEING. THIS STUDY WILL TEST THE IMPACT ON COMMUNITY-LEVEL HEALTH-RELATED QUALITY OF LIFE AND MENTAL HEALTH OF A COMMUNITY-ENGAGED, COMMUNITY-LEVEL INTERVENTION THAT AIMS TO IMPROVE PARK-BASED HEALTH AND SOCIAL PROGRAMMING. THE STUDY WILL LEVERAGE NEIGHBORHOOD PARKS THAT HAVE RECENTLY BEEN REDESIGNED AND RENOVATED AS PART OF THE COMMUNITY PARKS INITIATIVE, A CAPITAL INVESTMENT AND PARK EQUITY PROGRAM IN NEW YORK CITY. WE AIM TO WORK WITH EIGHT LOWER INCOME AND PREDOMINANTLY LATINO AND BLACK NEIGHBORHOODS THROUGH AN ASSET-BASED AND HUMAN-CENTERED DESIGN PROCESS TO CO-CREATE AND IMPLEMENT ONE HEALTH AND ONE SOCIAL STRATEGY IN EACH NEIGHBORHOOD PARK. THE HEALTH STRATEGY WILL FOCUS ON PHYSICAL ACTIVITY AND THE SOCIAL STRATEGY WILL SEEK TO ENHANCE SOCIAL RELATIONSHIPS AND NETWORKS IN EACH NEIGHBORHOOD. ACHIEVING BROAD REACH, INCLUSIVITY, AND SUSTAINABILITY ARE KEY FACTORS THAT WILL BE TAKEN INTO ACCOUNT IN THE DESIGN PROCESS. THE EIGHT NEIGHBORHOODS WILL BE CLUSTER-RANDOMIZED TO ONE OF TWO STEPS IN A STEPPED WEDGE INTERVENTION TRIAL. THE INTERVENTION IS 24 MONTHS IN EACH COMMUNITY, WITH FOLLOW-UP TO 48 MONTHS. WE WILL STUDY OUTCOMES, INCLUDING HR-QOL, DEPRESSION, ANXIETY, STRESS AND LONELINESS, AT THE COMMUNITY LEVEL (NOT AMONG INDIVIDUALS PARTICIPATING IN PARK ACTIVITIES) VIA RANDOM, REPRESENTATIVE SAMPLES OF ADULT RESIDENTS IN PARTICIPATING COMMUNITIES AT INTERVENTION BASELINE AND MONTHS 24 AND 48 POST-BASELINE.IN ADDITION, WE WILL EXAMINE WHETHER THE INTERVENTION EFFECTS MIGHT BE MEDIATED THROUGH SOCIAL COHESION, NEIGHBORHOOD TIES, SENSE OF COMMUNITY, PARK USE AND PERCEPTION AND/OR HEALTH BEHAVIORS SUCH AS PHYSICAL ACTIVITY AND SLEEP. FINALLY, WE WILL CONDUCT QUALITATIVE RESEARCH TO EXAMINE THE IMPLEMENTATION OF THE COMMUNITY-LEVEL INTERVENTION BASED ON CONSTRUCTS FROM THE CONSOLIDATED FRAMEWORK FOR IMPLEMENTATION RESEARCH. STUDY FINDINGS WILL HELP INFORM FUTURE BEST PRACTICES IN URBAN COMMUNITY DEVELOPMENT AND PARK PROGRAMS AND POLICIES TO PROMOTE POPULATION HEALTH AND REDUCE HEALTH DISPARITIES.

DRUG REPURPOSING FOR ALZHEIMER'S DISEASE USING STRUCTURAL SYSTEMS PHARMACOLOGY.

NATIONAL CENTER FOR BUILDING COMMUNITY TRUST AND JUSTICE

RESEARCH SUPPORT FOR BIOMEDICAL CAREERS AT CCNY

TAS::89 0336::TAS RECOVERY IN THIS PROJECT, THE CUNY ENERGY INSTITUTE, IN PARTNERSHIP WITH RECHARGEABLE BATTERY CORPORATION (RBC) AND ULTRALIFE CO

MINORITY YOUTH AND CENTERS FOR INDEPENDENT LIVING (MY-CIL)

NEW YORK CITY LOUIS STOKES ALLIANCE PHASE IV

HISPANIC-SERVING INSTITUTIONS PROGRAM (STEM)

IMPLEMENTATION RESEARCH TO ENHANCE EQUITY- FOCUSED HIV PREVENTION IN NEW YORK CITY

UNIVERSITY TRANSPORTATION CENTERS

HISPANIC-SERVING INSTITUTIONS PROGRAM (STEM)

HIGH GROWTH

PREDOMINANTLY BLACK INSTITUTIONS PROGRAM - FORMULA GRANTS

SNRP AT HUNTER COLLEGE

HISPANIC-SERVING INSTITUTIONS PROGRAM (STEM)

GAINING EARLY AWARENESS AND READINESS FOR UNDERGRADUATE PROGRAMS (GEAR-UP) - GEAR-UP

LEHMAN URBAN TEACHER EDUCATION-STEM: TEACHER QUALITY PARTNERSHIP WITH MICRO-CREDENTIALING IN COMPUTER SCIENCE

PIRE INVESTIGATION OF MULTI-SCALE, MULTI-PHASE PHENOMENA IN COMPLEX FLUIDS FOR THE ENERGY INDUSTRIES

CITY COLLEGE INITIATIVE TO PROMOTE THE ACADEMIC SUCCESS OF STEM STUDENTS – EXPERIENTIAL LEARNING & CAREER ENGAGEMENT INITIATIVE (CIPASS-EXLCEI)

CANCER EPIDEMIOLOGY EDUCATION IN SPECIAL POPULATIONS

MSPINNYC2 -- A NEW PARTNERSHIP TO TRANSFORM URBAN SECONDARY SCHOOL MATHEMATICS AND SCIENCE EXPERIENCES

CREST CENTER FOR INTERFACE DESIGN AND ENGINEERED ASSEMBLY OF LOW-DIMENSIONAL SYSTEMS (IDEALS)

CREST: CENTER FOR EXPLOITATION OF NANOSTRUCTURES IN SENSORS AND ENERGY SYSTEMS

BIOMEDICAL RESEARCH TRAINING FOR MINORITY HONOR STUDENTS

PROMOTING HISPANIC SCIENTISTS: A MODEL COLLEGE ARTICULATION PROGRAM TO PRODUCE TOMORROW’S STEM LEADERS

PHASE II CREST CENTER FOR INTERFACE DESIGN AND ENGINEERED ASSEMBLY OF LOW-DIMENSIONAL SYSTEMS (IDEALS II)

I-CORPS NODE: NEW YORK CITY REGIONAL INNOVATION NODE (NYCRIN)

MARC UNDERGRADUATE STUDENT TRAINING IN ACADEMIC RESEARCH

TRANSLATIONAL RESEARCH EXCELLENCE ACROSS DISCIPLINES (TREAD)

MATHEMATICS TEACHER TRANSFORMATION INSTITUTES

DEVELOPING A GROWTH MINDSET MODEL TO BUILD RESILIENCY IN STEM STUDENTS

LESION AND ACTIVITY DEPENDENT CORTICOSPINAL TRACT PLASTICITY

INTERVENTION TO REDUCE DRUG USE AND HIV INCIDENCE AMONG HIGH PREP PRIORITY PARTNERED YMSM

EXPANDQISE: TRACK 2: LEVERAGING SYNTHETIC DEGREES OF FREEDOM FOR QUANTUM STATE ENGINEERING IN PHOTONIC CHIPS -NONTECHNICAL ABSTRACT: THIS EXPANDQISE PROGRAM AT THE CITY COLLEGE OF NEW YORK SEEKS TO ADVANCE THE FUNDAMENTAL UNDERSTANDING OF QUANTUM PHENOMENA IN ENGINEERED OPTICAL STRUCTURES ENDOWED WITH ADDITIONAL DEGREES OF FREEDOM BY MANIPULATING THE FUNDAMENTAL PROPERTIES OF LIGHT AND ITS INTERACTION WITH NANOMATERIALS. THIS INITIATIVE AIMS AT THE DEVELOPMENT OF NASCENT QUANTUM MATERIALS WITH NOVEL PROPERTIES THAT CAN BE ATTAINED BY COMBINING TOPOLOGICAL PHOTONIC PROPERTIES AND QUANTUM PROPERTIES OF LIGHT AND MATTER. THIS PROJECT ADVANCES THE FIELDS OF INTEGRATED QUANTUM PHOTONICS THROUGH THE SYSTEMATIC DISCOVERY OF NEW MATERIALS THAT POSSESS THE NECESSARY FUNCTIONALITIES TO ENABLE DEVELOPMENT OF NOVEL QUANTUM DEVICES. TO MAXIMIZE THE EFFECTIVENESS OF THE DISCOVERY PROCESS, THIS PROJECT COMBINES THEORETICAL AND EXPERIMENTAL EFFORTS FROM INTERDISCIPLINARY TEAMS, INCLUDING ACADEMIA (CITY COLLEGE AND UNIVERSITY OF CENTRAL FLORIDA) AND INDUSTRY. IN ADDITION TO ITS DIRECT SCIENTIFIC IMPACT, THE PROJECT WILL HAVE A BROAD SOCIETAL IMPACT THROUGH THE DEVELOPMENT OF EMERGING TECHNOLOGIES FOR QUANTUM INFORMATION PROCESSING AND ADVANCES ONGOING WORKFORCE DEVELOPMENT EFFORTS THANKS TO THE STRONG INVOLVEMENT OF UNDERGRADUATE STUDENTS IN ALL ASPECTS OF RESEARCH. OUTREACH PROGRAMS WITH ACTIVE PARTICIPATION OF HIGH SCHOOL AND UNDERGRADUATE STUDENTS, WITH FOCUS ON UNDERREPRESENTED GROUPS, WILL FURTHER BROADEN THE PROJECT IMPACT. TECHNICAL ABSTRACT: THIS EXPANDQISE PROGRAM AT THE CITY COLLEGE OF NEW YORK SEEKS TO ADDRESS FUNDAMENTAL QUESTIONS OF MATERIALS SCIENCE AND LIGHT-MATTER INTERACTIONS IN ARTIFICIAL QUANTUM OPTICAL MATERIALS ENDOWED WITH ADDITIONAL SYNTHETIC DEGREES OF FREEDOM ? PSEUDO-SPINS ? AND CHARACTERIZED BY NONTRIVIAL TOPOLOGICAL PROPERTIES. OUR RESEARCH TEAM BUILDS ON OUR EXISTING EXPERTISE IN THEORETICAL NANO-PHOTONICS AS WELL AS ADVANCED FABRICATION AND EXPERIMENTAL TECHNIQUES TO ATTAIN NOVEL MATERIALS CHARACTERISTICS AND FUNCTIONALITIES EMERGING IN QUANTUM REGIMES. SPECIFICALLY, THIS ACTIVITY FOCUSES ON DEVELOPMENT OF THE CONCEPT OF ACTIVE QUANTUM TOPOLOGICAL MATERIALS THAT WILL ENABLE CONTROL OVER QUANTUM EXCITATIONS OF BOTH LIGHT AND MATTER ON A PHOTONIC CHIP. THIS EFFORT ENABLES GENERATION AND MANIPULATION OF QUANTUM STATES OF STRUCTURED OPTICAL MODES AND TOPOLOGICAL BOUNDARY STATES ENDOWED WITH SYNTHETIC DEGREES OF FREEDOM ON A CHIP. ADDITIONALLY, BY HARNESSING THE FUNDAMENTAL PROPERTIES OF SUCH QUANTUM PHOTONIC STATES THIS PROJECT ENABLES NOVEL POLARITONIC STATES WITH TAILORED PROPERTIES THAT CAN BE USED FOR QUANTUM TECHNOLOGIES, SUCH AS CONTROL OF PSEUDO-SPINS WITH SYNTHETIC GAUGE FIELDS ENGINEERED AT NANOSCALE, INCLUDING ACTIVELY VIA LIGHT-MATTER INTERACTIONS. THE POSSIBILITY TO IMPRINT THE STATE OF A PSEUDO-SPIN ONTO QUANTUM STATES OF LIGHT EMITTED BY INTEGRATED QUANTUM EMITTERS ENABLES NOVEL OPPORTUNITIES FOR INTEGRATED QUANTUM PHOTONICS, WHERE QUANTUM INFORMATION IS ENCODED IN THE MODAL STRUCTURE OF OPTICAL STATES. OUR APPROACH TO QUANTUM MATERIALS DESIGN LEVERAGES A VARIETY OF QUANTUM EXCITATIONS IN MATERIALS INTEGRATED INTO TOPOLOGICAL PHOTONIC STRUCTURES, SUCH AS VAN DER WAALS MATERIALS, ORGANIC EXCITONIC MATERIALS, AND WIDE BANDGAP SEMICONDUCTORS. THE COUPLING OF STRUCTURED LIGHT WITH QUANTUM EMITTERS IS ATTAINED THROUGH THEIR PRECISE INTEGRATION. AT THE SAME TIME, STRONG AND HIGHLY TAILORABLE LIGHT-MATTER INTERACTIONS ENGINEERED IN OUR PLATFORM ENABLE EXTREME NONLINEARITIES, INCLUDING NONLINEAR EFFECTS WITH SELECTION RULES DICTATED BY SYMMETRY-ENGINEERED PSEUDO-SPINS, PHOTON BLOCKADE AND SYNTHETIC GAUGE FIELDS. TUNABLE SYNTHETIC GAUGE FIELDS EMERGING FROM SUCH TAILORED LIGHT-MATTER INTERACTIONS OPEN A PATHWAY TO REALIZE UNITARY OPERATIONS ? REPROGRAMMABLE QUANTUM GATES ? IN THE PHOTONIC PSEUDO-SPIN SUBSPACE. THIS PROJECT IS JOINTLY FUNDED BY THE OFFICE OF MULTIDISCIPLINARY ACTIVITIES (MPS/OMA), THE DIRECTORATE OF ENGINEERING (ENG), AND THE TECHNOLOGY FRONTIERS PROGRAM (TIP/TF). THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

OVERVIEW: A JOINT RESEARCH AND EDUCATION CENTER WILL BE ESTABLISHED BETWEEN THE CITY COLLEGE OF NEW YORK (CCNY) NASA S JET PROPULSION LAB (JPL) AND NORTHEASTERN UNIVERSITY WHICH WILL FORM A HIGHLY COLLABORATIVE RESEARCH NETWORK IN ELECTROCHEMICAL ENERGY STORAGE AND TRAIN A DIVERSE STEM WORKFORCE THROUGH A MULTI-FACETED STUDENT INTERNSHIP PROGRAM. CCNY BRINGS EXTENSIVE EXPERTISE IN NOVEL BATTERY DEVELOPMENT MINORITY STUDENT TRAINING AND RECRUITMENT AND MANAGEMENT. NORTHEASTERN UNIVERSITY BRINGS EXPERIENCE IN ADVANCED BATTERY CHARACTERIZATION PARTICULARLY AT NATIONAL LABORATORIES WHILE JPL BRINGS DEEP KNOWLEDGE OF BATTERIES FOR SPACEFLIGHT AS WELL AS FACILITIES THAT PERMIT DEVICE TESTING UNDER THE EXTREME CONDITIONS ENCOUNTERED IN SPACE.

FY 2009 TEACHER QUALITY PARTNERSHIPS GRANTS

INDEPENDENT INITIATIVE

HISPANIC-SERVING INSTITUTIONS PROGRAM (STEM)

EXPANDING THE POTENTIAL OF COUPLES HIV TESTING: ADJUNCT MODULES TO REDUCE DRUG USE AMONG VULNERABLE MALE COUPLES

AWARD PURPOSE THE CUNY CONSTRUCTION SKILLS CONSORTIUM SEEKS TO CREATE A PATHWAY THAT STREAMLINES, ALIGNS AND CONNECTS CONSTRUCTION TRAINING FROM HIGH SCHOOL AND COMMUNITY PROVIDERS TO COLLEGES AND EMPLOYERS, ACCELERATES CERTIFICATIONS AND CREDIT AND DEGREE ATTAINMENT INCREASES ENTRY-LEVEL EMPLOYMENT AT LIVING WAGES, PROVIDES WORK-BASED LEARNING, AND SUPPORTS EQUITABLE CAREER ADVANCEMENT IN THE NYC CONSTRUCTION INDUSTRY ACTIVITIES PERFORMED THE CONSORTIUM WILL CONVENE AND WORK THROUGH AN ADVISORY COUNCIL, A STEERING COMMITTEE AND WORKING COMMITTEES ON CURRICULUM UPDATES AND DESIGN, PRIOR LEARNING CREDIT, ARTICULATION, PROCESS MAPPING, AND DATA ANALYSIS. THE CONSORTIUM WILL (I). ASSESS AVAILABLE CONSTRUCTION SKILLS PROGRAMS, THEIR STRENGTHS, WEAKNESSES, ALIGNMENT WITH INDUSTRY, AND ARTICULATION TO CERTIFICATES AND DEGREES. (II). WORK WITH EMPLOYERS TO CREATE NONCREDIT AND CREDIT-BEARING CONSTRUCTION SKILLS COURSES ALONG A CAREER PATHWAY, MICRO-, AND STACKABLE CREDENTIALS, AND INTEGRATED SUPPORTS (I.E., CONTEXTUALIZED MATH, SOFT SKILLS TRAINING, AND CAREER PLANNING). (III). DEVELOP ALIGNMENT AND ARTICULATION WITH CUNY ACADEMIC DEGREE PROGRAMS. (IV). DEVELOP A PLAN TO AWARD CREDIT FOR PRIOR LEARNING. (V). INTRODUCE WORK-BASED LEARNING. (VI). ENSURE CUNY INSTRUCTORS AND TRAINING FACILITIES ARE NCCER CREDENTIALED. DELIVERABLES CAPACITY BUILDING OUTCOME 1: THE CONSORTIUM SEEKS TO CREATE A CONSTRUCTION CAREER PATHWAY THAT EXTENDS FROM HIGH SCHOOL COMPLETION (OR GED) AND COMMUNITY-BASED CONSTRUCTION SKILLS TRAINING (E.G. YOUTHBUILD) TO CERTIFICATIONS TO DEGREE ATTAINMENT TO EMPLOYMENT AND CAREER ADVANCEMENT. CAPACITY BUILDING OUTCOME 2: CUNY COLLEGES WILL STRENGTHEN THEIR CAPACITY TO SUPPORT WORKER PERSISTENCE IN CONSTRUCTION SKILLS TRAINING AND EDUCATION AND THEIR RETENTION IN EMPLOYMENT BY OFFERING COMPREHENSIVE SUPPORTS. CAPACITY BUILDING OUTCOME 3: CUNY COLLEGES WILL BUILD THEIR CAPACITY TO COLLECT, ANALYZE, INTEGRATE, AND REPORT ON DATA WITH AN EQUITY LENS AND ACROSS CAMPUSES TO IMPROVE STUDENT AND PROGRAM PERFORMANCE. EQUITY OUTCOME 1: WORKERS WHO ARE UNDERREPRESENTED IN NYC'S CONSTRUCTION INDUSTRY WILL GAIN SKILLS AND CREDENTIALS NEEDED TO ENTER AND ADVANCE IN THE FIELD. EQUITY OUTCOME 2: WORKERS WHO ARE UNDERREPRESENTED IN NYC'S CONSTRUCTION INDUSTRY WILL BE PLACED AND RETAINED IN JOBS THAT EARN AT LEAST $20 PER HOUR. DESCRIPTION OF STUDENT COHORT TO BE USED FOR PARTICIPANT TRACKING: INDIVIDUALS WHO HAVE BEEN TRADITIONALLY UNDERREPRESENTED IN THE NYC CONSTRUCTION INDUSTRY, INCLUDING HISPANIC, BLACK, AAPI AND WOMEN WORKERS, AND INCLUDING NEW WORKERS, DISLOCATED WORKERS, AND INCUMBENT WORKERS ENROLLED INTO CONSTRUCTION SKILLS TRAINING AT A CONSORTIUM COLLEGE. INTENDED BENEFICIARY INDIVIDUALS WHO HAVE BEEN TRADITIONALLY UNDERREPRESENTED IN THE NYC CONSTRUCTION INDUSTRY, INCLUDING HISPANIC, BLACK, AAPI AND WOMEN WORKERS, AND INCLUDING NEW WORKERS, DISLOCATED WORKERS, AND INCUMBENT WORKERS SUBRECIPIENT ACTIVITIES LAGUARDIA AND CITY TECH'S ROLES WILL BE ASSESSING PROGRAM STRENGTHS AND WEAKNESSES, DEVELOPING/ENHANCING COURSES, TRAINING AND PLACING STUDENTS, RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK ON BEHALF OF BRONX COMMUNITY COLLEGE_NY_ABSTRACT EXPANDING OUR CAPACITY TO RETAIN STUDENTS BY ADDING COMPREHENSIVE SUPPORT, BROADENING ACCESS TO TRAINING BY CREATING A CONTEXTUALIZED MATH BRIDGE, ALIGNING CERTIFICATES WITH COLLEGE CREDITS/DEGREE PROGRAMS, DEVELOPING CREDIT FOR PRIOR LEARNING OPPORTUNITIES, ENHANCING DATA COLLECTION AND STRENGTHENING THE EQUITY FOCUS OF OUR WORK. BUILDING SKILLS NY'S WILL SOURCE JOBS, VET, PLACE AND HELP RETAIN APPLICANTS, WORK WITH EMPLOYER PARTNERS AND THE INDUSTRY TO REVIEW TRAINING CURRICULUM, PROVIDE FEEDBACK, AND SUPPORT THE CREATION OF SOFT SKILLS CURRICULUM TO PREPARE WORKERS FOR EMPLOYMENT. EMPLOYER-PARTNERS INCLUDING ACE CARPENTRY (CARPENTRY), GLO ELECTRIC (ELECTRICAL), SC PRIME (HVAC), DDM MECHANICAL (PLUMBING), KING CONTRACTING AND CITIBRIX AND TILE (BOTH MASONRY) WILL PROVIDE DETAILED INFORMATION ON NEEDS, TRENDS, AND SKILLS IN THEIR TRADES. NCCER WILL REVIEW THE CURRICULUM, PROVIDE AND TAKE INPUT FROM EMPLOYERS AND WORK WITH THE COLLEGES TO UPDATE AND DESIGN CURRICULUM, AND WORK TO FOSTER A PIPELINE FROM HIGH SCHOOLS THAT TEACH NCCER TO THE CONSORTIUM TRAINING AND JOBS. COMMUNITY-BASED CONSTRUCTION SKILLS TRAINERS – RENAISSANCE TECHNICAL INSTITUTE POSITIVE WORKFORCE AND CENTRAL BROOKLYN EDC – WILL BE PAID RENT TO PROVIDE TRAINING FACILITIES FOR THE PROGRAM, WILL REFER PEOPLE TO THE PROGRAM, AND WILL SIT ON THE ADVISORY COUNCIL.

OPTIMIZING HIV PREVENTION FOR HIGHLY VULNERABLE METHAMPHETAMINE-USING SEXUAL MINORITY MEN - SUMMARY THIS LITE-2 (RFA-AI-21-018) INITIATIVE RESPONDS TO A RESURGENT EPIDEMIC OF METHAMPHETAMINE (METH) USE IN SEXUAL MINORITY MEN (SMM), WHICH IS A PRIMARY DRIVER OF HIV INCIDENCE. THE OVERARCHING GOALS ARE TWO-FOLD: 1) IDENTIFY MULTI-LEVEL AND BIO-BEHAVIORAL DETERMINANTS OF AMPLIFIED HIV SEROCONVERSION RISK IN METH-USING SMM; AND 2) TEST THE EFFECTIVENESS OF TELEHEALTH MOTIVATIONAL ENHANCEMENT INTERVENTIONS FOR OPTIMIZING ENTRY OR RE-ENTRY OF SMM WHO USE METH INTO THE PREP CARE CONTINUUM. FINDINGS FROM OUR LITE-1 COHORT (UG3/UH3 AI-133675, RFA-AI-16-031) AND OTHERS PROVIDE COMPELLING EVIDENCE THAT METH USE IS INCREASING, DISPROPORTIONALLY IMPACTS RACIAL/ETHNIC MINORITIES, AND ACCOUNTS FOR ONE-IN-THREE NEW HIV INFECTIONS IN SMM. IN RESPONSE TO LITE-2 (RFA- AI-21-018) WE PROPOSE A MULTI-COMPONENT INITIATIVE ZEROING IN ON THE “WHERE,” “HOW,” AND “WHY” OF METH USE AND HIV RISK. WHERE: WHAT ARE THE GEOSPATIAL DETERMINANTS OF THE ASSOCIATION OF METH USE WITH HIV INCIDENCE? HOW: HOW CAN WE SUPPORT (RE-)ENTRY INTO THE PREP CARE CONTINUUM WITH THIS HIGH PRIORITY POPULATION OF SMM WHO USE METH? WHY: DOES METH AMPLIFY BIOLOGICAL RISK OF HIV BY POTENTIATING RECTAL IMMUNE DYSREGULATION? AIM 1: EXAMINE MULTI-LEVEL STRUCTURAL, PSYCHOLOGICAL, AND SOCIAL DETERMINANTS OF AMPLIFIED HIV SEROCONVERSION RISK IN SMM WHO USE METH. THE CENTERPIECE OF OUR LITE-2 INITIATIVE IS A NEW PROSPECTIVE, BIO-BEHAVIORAL COHORT WITH N=5,000 SMM (N=3,000 SMM WHO USE METH, N=2,000 WHO DO NOT). PARTICIPANTS WILL COMPLETE ASSESSMENTS OVER 36 MONTHS AND PROVIDE BIOLOGICAL SAMPLES FOR HIV TESTING, DRUG TOXICOLOGY TESTING, RECTAL STIS, AND RECTAL CYTOKINES/CHEMOKINES. OUR PRIMARY GOAL WILL BE TO INVESTIGATE THE ROLE OF GEOSPATIAL DETERMINANTS (E.G., BACKGROUND METH AND HIV PREVALENCE, URBANICITY) AND OTHER STRUCTURAL DETERMINANTS (E.G., STRUCTURAL STIGMA OF SEXUAL MINORITIES AS EVIDENCED BY POLICIES/LAWS) IN RELATION TO THE ASSOCIATION OF METH USE WITH AMPLIFIED HIV SEROCONVERSION RISK. AIM 2: TEST THE COMPARATIVE AND COMBINED EFFECTIVENESS OF TELEHEALTH MOTIVATIONAL ENHANCEMENT INTERVENTIONS FOR OPTIMIZING PREP USE. PREP READINESS INTERVENTIONS FOR SUPPORTING MOTIVATION (PRISM) IS A HYBRID TYPE I, MODIFIED FACTORIAL RANDOMIZED CONTROLLED TRIAL (RCT) OF TELEHEALTH CM THAT PROVIDES INCENTIVES FOR FILLING A PREP PRESCRIPTION, AND A 2-SESSION TELEHEALTH MI INTERVENTION THAT WE ADAPTED WITH METH- USING SMM (R34-DA046367, CARRICO/GROV). PRISM WILL ENROLL 840 METH-USING SMM WHO ARE NOT CURRENTLY TAKING PREP FROM THE LITE-2 COHORT (AIM 1) TO EXAMINE THE EFFECTIVENESS OF CM (N = 280), MI (N = 280), AND MI+CM (N = 280) ON THE PRIMARY OUTCOME – FILLING A PREP PRESCRIPTION. AIM 3: DETERMINE WHETHER GREATER RECTAL IMMUNE DYSREGULATION PARTIALLY EXPLAINS AMPLIFIED RISK OF HIV SEROCONVERSION IN SMM WHO USE METH. USING A CASE-COHORT DESIGN, WE WILL COMPARE HIV SEROCONVERTERS (N=450) WITH MATCHED SERONEGATIVE CONTROLS (N=450) TO EXAMINE THE CLINICAL RELEVANCE OF METH-INDUCED ALTERATIONS IN RECTAL CYTOKINES WITH RESPECT TO HIV SEROCONVERSION. THIS LITE-2 INITIATIVE COULD HAVE AN EXCEPTIONAL IMPACT BY TRANSFORMING HIV PREVENTION WITH SMM.

MECHANISTIC PRINCIPLES OF SIGNAL DETECTION AND TRANSMISSION IN BACTERIAL TWO-COMP

** AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** ACROSS THE UNITED STATES, THERE IS A GROWING NEED FOR AGRICULTURAL PROFESSIONALS WHO CAN STRENGTHEN THE HEALTH, PRODUCTIVITY, AND APPLIED WORKFORCE READINESS OF OUR FOOD AND AGRICULTURAL SYSTEMS. FROM ANIMAL AND PLANT SCIENCES TO NUTRITION, CONSERVATION, AND ENVIRONMENTAL MANAGEMENT, THESE DISCIPLINES ARE CRITICAL TO SUPPORTING A SECURE FOOD SUPPLY, PROPERTY OR NATURAL RESOURCES, AND ADVANCING THE USDA'S MISSION IN FOOD, AGRICULTURE, NATURAL RESOURCES, AND HUMAN SCIENCES (FANH). MANY REGIONS ALSO FACE SHORTAGES OF SPECIALISTS, PARTICULARLY IN VETERINARY MEDICINE WHO SUPPORT LIVESTOCK HEALTH AND FOOD PRODUCTION, UNDERSCORING THE IMPORTANCE OF PREPARING THE NEXT GENERATION OF SKILLED AGRICULTURAL PROFESSIONALS INCLUDING FARMERS, RANCHERS AND PRODUCERS.TO ADDRESS THESE NEEDS, LAGUARDIA COMMUNITY COLLEGE (LAGCC) IN QUEENS, NEW YORK, HAS PARTNERED WITH RUTGERS UNIVERSITY IN NEW JERSEY TO ESTABLISH THE ANIMAL SCIENCE DISCOVERY (ANSCID) PROGRAM. THIS INITIATIVE ESTABLISHES A STRUCTURED EDUCATIONAL PATHWAY FROM SECONDARY EDUCATION THROUGH COMMUNITY COLLEGE AND INTO FOUR-YEAR DEGREE PROGRAMS IN ANIMAL SCIENCE, PRE-VETERINARY STUDIES, ANIMAL AND PLANT INSPECTION SERVICES, OR RELATED FIELDS OF FANH. THROUGH HANDS-ON, WORK-BASED LEARNING, EXPERIENTIAL LEARNING, PAID SUMMER RESEARCH, ACADEMIC ADVISING, AND MENTORSHIP, ANSCID HELPS STUDENTS DEVELOP THE SCIENTIFIC KNOWLEDGE, TECHNICAL SKILLS, AND PROFESSIONAL CONFIDENCE NEEDED TO SUCCEED IN VETERINARY SCIENCE, AGRICULTURE AND THE LIFE SCIENCES.

MBRS SCORE PROGRAM AT CITY COLLEGE OF CUNY

TRANSLATIONAL RESEARCH TRAINING ON ADDICTIONS FOR RACIAL/ETHNIC MINORITIES

QUEENSBOROUGH COMMUNITY COLLEGE?S (QCC) BRIDGES TO THE BACCALAUREATE PROGRAM

REGIONAL TRAINING ACADEMY

THE NEW YORK CITY RETIREMENT AND DISABILITY RESEARCH CONSORTIUM NYC-RDRC

ARTIFICIAL INTELLIGENCE, MODELING, AND INFORMATICS FOR NUTRITION GUIDANCE AND SYSTEMS (AIMINGS) CENTER - ABSTRACT – OVERALL AIMINGS CENTER THE VISION OF THIS PROPOSED ARTIFICIAL INTELLIGENCE, MODELING, AND INFORMATICS, FOR NUTRITION GUIDANCE AND SYSTEMS (AIMINGS) CENTER IS TO IMPLEMENT COMPUTATIONAL AND DATA SCIENCE APPROACHES AND TOOLS TO ADVANCE NUTRITION FOR PRECISION HEALTH IN A WAY THAT ACCOUNTS FOR THE COMPLEX SYSTEMS INVOLVED. MANY EXISTING DATA SETS INCLUDE EXTRANEOUS DATA, MAKING THEM DIFFICULT TO ANALYZE AT BEST, AND AT WORST, PRONE TO GENERATING MISLEADING OR BIASED INSIGHTS. THUS, THERE IS A NEED TO FOR NEW APPROACHES, METHODS, AND TOOLS TO COLLAPSE AND DISTILL DATA TO MAKE THEM MORE ARTIFICIAL INTELLIGENCE (AI)-READY AND READY FOR A RANGE OF DIFFERENT ANALYSES. THIS COINCIDES WITH THE GOAL OF PROJECT 1: TO DEVELOP AND UTILIZE THE DATA DISTILLER FOR PRECISION NUTRITION, A SET OF APPROACHED AND TOOLS THAT CAN COLLAPSE AND DISTILL NUTRITION-RELEVANT DATA TO CREATE DATASETS THAT ARE AI- READY AND READY FOR A RANGE OF OTHER ANALYSES. THE FIRST OBJECTIVE OF THE NUTRITION FOR PRECISION HEALTH (NPH) PROGRAM IS TO “EXAMINE INDIVIDUAL DIFFERENCES OBSERVED IN RESPONSE TO DIFFERENT DIETS BY STUDYING THE INTERACTIONS BETWEEN DIET, GENES, PROTEINS, MICROBIOME, METABOLISM AND OTHER INDIVIDUAL CONTEXTUAL FACTORS.” GIVEN THE TYPE OF MISSING DATA WE FACE IN NUTRITION, AND THE IMPORTANCE OF ESTABLISHING CAUSAL RELATIONSHIPS RATHER THAN CORRELATIONS, THERE IS A NEED FOR NEW IMPUTATION METHODS. TO ADDRESS THIS, PROJECT 2, THE CAUSAL RELATIONSHIP DISENTANGLER, WILL INTRODUCE NEW APPROACHES FOR HANDLING MISSING DATA WHILE PRESERVING CAUSAL STRUCTURE. LEARNING HOW TO TRANSFER CAUSAL KNOWLEDGE AND DOING SO WITH MISSING DATA IS CRITICAL FOR REALIZING THE POTENTIAL OF NUTRITION FOR PRECISION HEALTH. THE NPH PROGRAM’S OTHER OBJECTIVES ARE “TO USE AI TO DEVELOP ALGORITHMS TO PREDICT INDIVIDUAL RESPONSES TO FOODS AND DIETARY PATTERNS,” AND “TO VALIDATE ALGORITHMS FOR CLINICAL APPLICATION.” THIS REQUIRES BRINGING DIFFERENT CAUSAL PATHWAYS TOGETHER TO UNDERSTAND HOW THEY INTERACT. AGENT-BASED MODELS (ABMS) CAN HELP AND SERVE AS "VIRTUAL LABORATORIES" TO PREDICT HOW DIFFERENT PEOPLE MAY RESPOND TO A PARTICULAR DIET UNDER DIFFERENT CIRCUMSTANCES. THEREFORE, THE GOAL OF PROJECT 3 (THE VIRTUAL HUMAN FOR PRECISION NUTRITION) IS TO DEVELOP AN ABM TOOL THAT CAN HELP BETTER UNDERSTAND AND PREDICT AN INDIVIDUAL'S RESPONSE TO FOOD AND DIETARY PATTERNS, WHILE BRINGING TOGETHER AND ACCOUNTING FOR THE INTERACTIONS BETWEEN GENETIC, PHYSIOLOGICAL, AND BEHAVIORAL FACTORS. HOWEVER, FOCUSING ON THE INDIVIDUAL ALONE WILL NOT BE ENOUGH TO ADDRESS ALL ASPECTS OF NPH. THEREFORE, THE VIRTUAL PUBLIC HEALTH PRECISION NUTRITION LABORATORY (PROJECT 4) WILL DEVELOP ABMS THAT REPRESENT AND ACCOUNT FOR THE SYSTEMS OUTSIDE INDIVIDUALS SUCH AS THEIR SOCIAL, ECONOMIC, AND BUILT ENVIRONMENTS. AN ADMINISTRATIVE AND COORDINATION CORE WILL OVERSEE ALL OPERATIONS AND A PILOT PROGRAM. A DATA SYSTEMS CORE (DSC) WILL LEVERAGE THE SUBSTANTIAL COMPUTING RESOURCES OF CUNY, WEST POINT, AND THE DEPARTMENT OF DEFENSE TO CREATE A FLEXIBLE CLOUD-BASED ARCHITECTURE FOR DATA FLOW AND A COLLABORATIVE WORKSPACE. A COMPUTATIONAL SYSTEMS CORE WILL PROVIDE RESOURCES AND PERSONNEL TO SUPPORT THE DSC AND TOOL DEVELOPMENT/DEPLOYMENT.

UNIV RESEARCH CTR FOR OPTICAL SENSING & IMAGING OF THE EARTH AND ENVIRONMENT

HISTONE DEACETYLATION IN OLIGODENDROCYTE DIFFERENTIATION

ROLE OF CELL CYCLE INHIBITORS IN ADULT NEURAL STEM CELLS

G-RISE AT THE CITY COLLEGE OF NEW YORK

THE ROLE OF TYPE VI SECRETION IN CHOLERA PATHOGENESIS

NEW; STUDIES OF PHOTOSYNTHETIC REACTION CENTERS AND BIOMIMETIC SYSTEMS; PI- MARILYN GUNNER

SYNTHESIZING BEST PRACTICE TO ACCELERATE ACCESS TO EMERGING HIV PREVENTION MODALITIES

HIGHER EDUCATION - INSTITUTIONAL AID - STRENGTHENING INSTITUTIONS - HISPANIC SERVING INSTITUTIONS

TEACHER QUALITY ENHANCEMENT GRANTS FOR STATE AND PARTNERSHIPS - PARTNERSHIP GRANTS

HARLEM STRONG MENTAL HEALTH COALITION: A MULTI-SECTOR COMMUNITY-ENGAGED COLLABORATIVE FOR SYSTEM TRANSFORMATION

SELF-PROGRAMMABLE METASURFACE NETWORKS FOR WIRELESS COMMUNICATIONS AND IOT

I-CORPS NODE (TRACK 2): NEW YORK CITY REGIONAL INNOVATION NODE (NYCRIN)

PREPARING FOR IMPLEMENTATION OF SUSTAINED RELEASE ANTIVIRALS FOR HIV PREVENTION

THE CENTRAL BROOKLYN VIOLENCE INTERVENTION COLLABORATIVE WILL PROVIDE TECHNICAL ASSISTANCE, CAPACITY BUILDING AND WORKFORCE DEVELOPMENT SERVICES TO A CORE TEAM OF COMMUNITY VIOLENCE INTERVENTION AGENCIES OPERATING IN CENTRAL BROOKLYN, NY. A KEY FOCUS OF THESE EFFORTS IS TO POSITION CVI TEAMS AS A PILLAR OF PUBLIC SAFETY AND PUBLIC HEALTH IN THEIR COMMUNITIES AND TO BETTER INTEGRATE THEIR TEAMS WITH THE EXISTING INFRASTRUCTURE OF PUBLIC SAFETY, HEALTHCARE, HOUSING, AND SOCIAL SERVICE PROVIDERS. IN WORKING TOWARDS THE GOAL OF REDUCING GUN VIOLENCE IN CENTRAL BROOKLYN, THE KEY OBJECTIVES OF THE COLLABORATIVE WILL BE TO: 1) ENHANCE STRATEGIC PLANNING AND PURPOSEFUL COLLABORATION AMONG CVI TEAMS THEMSELVES AND WITH KEY PUBLIC SAFETY STAKEHOLDERS; 2) BUILD A CULTURE OF CONTINUOUS WORKFORCE DEVELOPMENT OPPORTUNITIES TO STRENGTHEN THE TEAMS AT ALL LEVELS; 3) INCREASE CVI CAPACITY TO NAVIGATE AND PARTNER WITH LOCAL HEALTH, MENTAL HEALTH, SUBSTANCE USE, HOUSING, EDUCATION AND OTHER SOCIAL SERVICE PROVIDERS; 4) IMPROVE CLIENT NEEDS ASSESSMENTS AND CASE MANAGEMENT INFRASTRUCTURE; AND 5) DEVELOP STANDARDIZED DATA COLLECTION AND SHARING PROTOCOLS.

LOUIS STOKES STEM PATHWAYS AND RESEARCH ALLIANCE: NYC LSAMP ALLIANCE

HIGH GROWTH

HISPANIC-SERVING INSTITUTIONS PROGRAM (STEM)

PREDICTORS OF ADHD IN PRESCHOOL CHILDREN

UNDERGRADUATE BIOMEDICAL RESEARCH TRAINING AT HUNTER

EXAMINING THE EFFICACY, PREDICTIVE POWER, AND COST EFFECTIVENESS OF THE DIAGNOSTIC ASSESSMENT AND ACHIEVEMENT OF COLLEGE SKILLS

BRONX COMMUNITY CENTER FOR SUSTAINABLE ENERGY

HISPANIC-SERVING INSTITUTIONS PROGRAM (STEM)

STRENGTHENING INSTITUTIONS - HISPANIC SERVING INSTITUTIONS

STRENGTHENING INSTITUTIONS - HISPANIC SERVING INSTITUTIONS

THE STAYING SAFE INTERVENTION: PREVENTING HCV AMONG YOUNG OPIOID INJECTORS

PREDOMINANTLY BLACK INSTITUTIONS

MINORITY ACCESS/GRADUATE NETWORKING IN THE SCIENCES, TECHNOLOGY, ENGINEERING, AND MATHEMATICS (MAGNET-STEM II

THE INFANTS OF SUPERSTORM SANDY:THE EPIGENETIC AND DEVELOPMENTAL IMPACT OF NATURAL DISASTER

HIGHER EDUCATION - INSTITUTIONAL AID - STRENGTHENING INSTITUTIONS - HISPANIC SERVING INSTITUTIONS

SYNDEMICS AND RESILIENCE FOR HIV TRANSMISSION IN A NATIONAL SAMPLE OF VULNERABLE

OSTEOCYTE INTEGRITY AND BONE REMODELING

SAFE AND JUST CLEANERS: REDUCING EXPOSURE TO TOXIC CLEANING CHEMICAL PRODUCTS AMONG LOW WAGE IMMIGRANT LATINO COMMUNITY MEMBERS

IMPROVING CLINICAL SPEECH REMEDIATION WITH ULTRASOUND TECHNOLOGY

MEDGAR EVERS/KINGSBOROUGH BRIDGE PROGRAM

MULTIMETHOD MEASUREMENT OF PROXIMAL RISK FOR PERSISTENT SUICIDE IDEATION AND FUTURE ATTEMPTS AMONG ADOLESCENTS

MEDGAR EVERS COLLEGE PREDOMINANTLY BLACK INSTITUTION INITIATIVE

CHARTING THE EVOLUTIONARY DEVELOPMENT OF NOVEL GENES AND THE MOLECULAR MECHANISMS OF GLAND TISSUE ORGANIZATIONIN CEPHALOPODS - ABSTRACT VENOM IS A COMPLEX TRAIT THAT HAS CONVERGENTLY EVOLVED IN OVER 200,000 ANIMALS ACROSS THE TREE OF LIFE, TOTALING APPROXIMATELY ~15-30% OF ANIMAL BIODIVERSITY. THE PREVALENCE OF THE VENOM PHENOTYPE DEMONSTRATES ITS MOLECULAR SUCCESS AND STUDYING ITS EVOLUTION HAS BROAD APPLICATIONS TO UNDERSTANDING THE DEVELOPMENT OF HOMOLOGOUS TISSUES, THE ORIGINS OF NOVEL GENES, AND THE MOLECULAR MECHANISMS BEHIND THE REGULATION AND EXPRESSION OF BIOACTIVE COMPOUNDS. CONSIDERABLY, VENOMS ARE THE PROTOTYPE OF PRECISION MEDICINE: INDUCING A HIGHLY SPECIFIC AND IMMEDIATE RESPONSE. THESE ATTRIBUTES HAVE FUELED DRUG DISCOVERY EFFORTS, LEADING TO BREAKTHROUGH VENOM-DERIVED THERAPEUTICS FOR A WIDE RANGE OF CONDITIONS, FROM DIABETES TO HEART DISEASE TO PAIN. HOWEVER, THE FULL POTENTIAL OF VENOM, IN BOTH MEDICINE AND BIOLOGICAL RESEARCH, IS UNTAPPED. THIS UNMET NEED ARISES BECAUSE OF THE LACK OF ROBUST MODELS FOR GENETICALLY MANIPULATING THE DEVELOPMENT OF VENOM GLANDS AND REGULATION AND EXPRESSION OF VENOM BIOACTIVE PEPTIDES. THE WORK OF THE HOLFORD GROUP WAS THE FIRST TO CHARACTERIZE TEREBRID VENOM PEPTIDES AS BIOACTIVE IN MITIGATING ANALGESIC AND ANTITUMOR ACTIVITY. HOWEVER, WITHOUT GUIDING PRINCIPLES FOR HOW VENOMS AND VENOM GLANDS DEVELOP IN VIVO, WE, AND OTHER VENOM RESEARCHERS, HAVE JUST SCRATCHED THE SURFACE. WE NEED MODEL SYSTEMS TO REVOLUTIONIZE THE STUDY VENOM GLAND BIOLOGY, SO THAT WE CAN RADICALLY TRANSFORM HOW WE GENERATE, MANIPULATE, AND UTILIZE VENOM ARSENALS. THE CEPHALOPOD BREEDING PROGRAM PROVIDE THE TOOLS AND MODELS NECESSARY TO TACKLE BIOLOGICAL AND TRANSLATIONAL QUESTIONS THAT HAVE REMAINED UNAPPROACHABLE, SUCH AS: WHAT DRIVES THE EXPRESSION OF PREDATORY VERSUS DEFENSIVE VENOM COMPONENTS? CAN WE MANIPULATE THE PRODUCTION OF SPECIFIC TOXINS WITH A DESIRED FUNCTION, SUCH AS THOSE TARGETING RECEPTORS INVOLVED IN ANALGESIC ACTIVITY? ADVANCEMENTS IN GENETIC ENGINEERING, GENOMICS, TRANSCRIPTOMICS, AND PROTEOMICS WILL ALLOW US TO GENERATE THE FIRST MARINE INVERTEBRATE TRANSGENIC CEPHALOPOD ORGANISMS THAT PRODUCE VENOM IN SPECIALIZED GLANDS THAT CAN BE INVESTIGATED TO EXPLORE FUNDAMENTAL QUESTIONS ABOUT TISSUE DEVELOPMENT AND GENE REGULATION AND EXPRESSION. SPECIFICALLY, WE WILL: (1) DETERMINE GENES AND PROTEINS RELEVANT TO VENOM GLAND DEVELOPMENT, MAINTENANCE, AND SECRETION ACROSS DIVERSE CEPHALOPOD TAXA. THIS OBJECTIVE WILL DETERMINE THE EVOLUTIONARY UNDERPINNINGS BETWEEN VENOM SALIVARY GLANDS AND OTHER EXOCRINE TISSUES ACROSS TAXA. (2) TRACE THE DEVELOPMENT OF CEPHALOPOD SALIVARY GLANDS. THIS OBJECTIVE WILL REVEAL GENETIC PATHWAYS THAT CAN BE LEVERAGED TO DETERMINE THE FORMATION AND FUNCTION OF VENOM GLAND FROM DIVERSE TAXA. (3) ESTABLISH COMPARATIVE CEPHALOPOD TRANSGENIC MODELS. THIS OBJECTIVE WILL ESTABLISH TRANSGENIC CEPHALOPODS ALLOWING US TO OPTIMIZE THE UTILITY OF VENOM GLANDS FOR UNDERSTANDING THE DEVELOPMENT OF HOMOLOGOUS TISSUES, THE ORIGINS OF NOVEL GENES, AND THE MOLECULAR MECHANISMS BEHIND THE REGULATION AND EXPRESSION OF BIOACTIVE COMPOUNDS. THE PROPOSED RESEARCH IS A NEW DIRECTION FOR THE PI THAT IS HIGH RISK-HIGH REWARD, AND WILL BENEFIT DISPARATE FIELDS AND INDUSTRIES, INCLUDING DEVELOPMENTAL CELLULAR AND MOLECULAR BIOLOGY AND DRUG DISCOVERY AND DEVELOPMENT. MOST DISEASES, LIKE ALZHEIMER OR CANCER HAVE COMPLEX TRAITS WHOSE GENETIC CHARACTERIZATION IN MODEL SYSTEMS HAVE BEEN ESSENTIAL TO FINDING EFFECTIVE THERAPIES. STUDYING THE EVOLUTIONARY GENETICS IN THE COMPLEX TRAIT OF VENOM IN A RELIABLY, CULTURED CEPHALOPOD SYSTEM WILL BROADLY IMPACT RESEARCH TOWARDS THE NIH’S MISSION OF ENHANCING HUMAN HEALTH.

BRIEF DIGITAL INTERVENTION TO INCREASE COVID-19 VACCINATION AMONG INDIVIDUALS WITH ANXIETY OR DEPRESSION - PROJECT SUMMARY DESPITE INCREASED RISK OF COVID-19 INFECTION, SEVERE COMPLICATIONS, HOSPITALIZATIONS, AND DEATH, PEOPLE WITH MENTAL HEALTH DISORDERS REPORT GREATER VACCINE HESITANCY AND HAVE LOWER COVID VACCINATION LEVELS THAN THE GENERAL POPULATION. INDIVIDUALS WITH MENTAL HEALTH DISORDERS ARE MUCH MORE LIKELY TO ENDORSE COVID-19 VACCINE MISINFORMATION, WHICH MAY MEDIATE THE RELATIONSHIP BETWEEN MENTAL HEALTH AND VACCINE HESITANCY. INTERVENTIONS CAPABLE OF MITIGATING THE IMPACT OF VACCINE HESITANCY, MIS/DISINFORMATION, AND LOGISTICAL BARRIERS AMONG UNVACCINATED PEOPLE WITH MENTAL HEALTH DISORDERS ARE AN URGENT PRIORITY. ATTITUDINAL INOCULATION IS A BRIEF, SCALABLE STRATEGY TO ADDRESS MIS/DISINFORMATION. IN A QUASI-EXPERIMENTAL TRIAL, OUR TEAM FOUND THAT A BRIEF ONLINE ATTITUDINAL INOCULATION INTERVENTION SPECIFICALLY ADDRESSING COVID-19 VACCINE MIS/DISINFORMATION SIGNIFICANTLY DECREASED COVID-19 VACCINE HESITANCY AND INCREASED RESISTANCE TO VACCINE MISINFORMATION AMONG UNVACCINATED US ADULTS. HOWEVER, ITS EFFECTIVENESS AMONG INDIVIDUALS WITH MENTAL HEALTH DISORDERS IS UNKNOWN. INFORMED BY INOCULATION THEORY, ATTITUDINAL INOCULATION LEVERAGES THE POWER OF NARRATIVE, VALUES, AND EMOTION TO STRENGTHEN RESISTANCE TO MISINFORMATION AND REDUCE HESITANCY AND IS WELL- SUITED FOR LOW-INFORMATION AUDIENCES AND IDEOLOGICALLY POLARIZED OR CONSPIRATORIAL GROUPS. THE PROPOSED RESEARCH PROJECT WILL LEVERAGE THE INFRASTRUCTURE OF THE NATIONAL CHASING COVID COHORT, A LARGE AND GEOGRAPHICALLY DIVERSE COMMUNITY-BASED US COHORT, TO TAILOR AND TEST THE EFFECTIVENESS OF A BRIEF DIGITAL ATTITUDINAL INOCULATION INTERVENTION TO INCREASE VACCINATION AMONG ADULTS WITH ANXIETY OR DEPRESSION SYMPTOMS. AIM 1: CHARACTERIZE THE RELATIONSHIP BETWEEN SYMPTOMS OF ANXIETY AND DEPRESSION AND VACCINE/BOOSTER UPTAKE, AND OTHER RELATED DETERMINANTS OF VACCINE UPTAKE (INCLUDING ENDORSEMENT OF COVID-19 MISINFORMATION AND VACCINE HESITANCY) AMONG THOSE WITH AND WITHOUT ANXIETY/DEPRESSION AIM 2: ADAPT AND PILOT AN EVIDENCE-BASED ATTITUDINAL INOCULATION INTERVENTION TO INCREASE COVID-19 VACCINATION AND BOOSTING AMONG ADULTS WITH SYMPTOMS OF ANXIETY OR DEPRESSION. AIM 3: DETERMINE THE EFFECTIVENESS OF TWO BRIEF DIGITAL ATTITUDINAL INOCULATION INTERVENTION STRATEGIES COMPARED WITH CONVENTIONAL PUBLIC HEALTH MESSAGING FOR INCREASING VACCINE UPTAKE IN UN/UNDERVACCINATED AND UNBOOSTED ADULTS. THIS STUDY DIRECTLY ADDRESSES THE PRIORITIES OF THE NATIONAL INSTITUTE OF MENTAL HEALTH AND THE PAR: COVID-19 MENTAL HEALTH RESEARCH (PAR-22-112) TO CONDUCT “INTERVENTION EFFECTIVENESS RESEARCH TO ADDRESS VACCINE HESITANCY, UPTAKE, AND IMPLEMENTATION AMONG MENTAL HEALTH POPULATIONS.” THIS RESEARCH WILL RAPIDLY GENERATE EVIDENCE TO INFORM THE DEVELOPMENT AND IMPLEMENTATION OF STRATEGIES TO INCREASE VACCINATION UPTAKE AND MITIGATE THE IMPACT OF COVID-19 AMONG MENTAL HEALTH POPULATIONS. BEYOND THE COVID PANDEMIC, THIS RESEARCH HAS DIRECT APPLICABILITY TO FUTURE PANDEMICS AND ROUTINE VACCINATION CAMPAIGNS.

INTERVENTION TO ENHANCE PREP UPTAKE AND ADHERENCE IN A COMMUNITY-BASED SETTING

MACHINE LEARNING FOR RISK-ADJUSTED BREAST MRI SCREENING - SUMMARY MAGNETIC RESONANCE IMAGING (MRI) IS THE MOST SENSITIVE IMAGING MODALITY FOR BREAST CANCER DIAGNOSIS TO DATE. WOMEN WITH A STRONG FAMILY HISTORY OR RELATED GENETIC MUTATIONS HAVE AN ELEVATED RISK OF BREAST CANCER AND ARE RECOMMENDED TO PARTICIPATE IN YEARLY MRI SCREENINGS. HOWEVER, THE RATE OF DETECTION IN THIS HIGH-RISK COHORT IS SMALL, PROMPTING A DESIRE TO REDUCE UNNECESSARY MRI EXAMS. THE BASIC HYPOTHESIS OF THIS PROJECT IS THAT WITHIN THE SCREENING COHORT THE INDIVIDUAL RISK OF A FUTURE CANCER CAN BE ESTIMATED BASED ON THE APPEARANCE OF BREAST MRI AND MAMMOGRAMS TODAY. IN PRELIMINARY WORK WE HAVE ALREADY IDENTIFIED LOW-RISK WOMEN THAT COULD HAVE OMITTED A SCREENING SESSION WITHOUT MISSING A NEW CANCER. THE DISCOVERY OF THIS LOWER-RISK SUBGROUP WAS MADE POSSIBLE BY MODERN DEEP-LEARNING TOOLS DEVELOPED IN PRELIMINARY WORK. MEMORIAL SLOAN KETTERING CANCER CENTER (MSK) HAS ACCRUED A DATABASE OF APPROXIMATELY 70,000 BREAST MRI EXAMS OVER 18 YEARS ALONG WITH THE PATIENTS’ CLINICAL OUTCOMES. THIS UNPRECEDENTED RESOURCE ENABLES THE TRAINING OF MODERN MACHINE LEARNING “FROM THE GROUND-UP” TO EXTRACT AND CLASSIFY VOLUMETRIC MRI FEATURES. THE SPECIFIC AIMS OF THIS PROJECT ARE AS FOLLOWS. AIM 1 (DATA CURATION): SYSTEMATIC ANALYSIS OF THE LARGE DATASET ACCRUED AT MSK REQUIRES CAREFUL CURATION INCLUDING IMAGE CONTENT, IMAGE QUALITY, PATHOLOGY RESULTS, CLINICAL FOLLOW-UP, AS WELL AS DEMOGRAPHIC AND GENOMIC INFORMATION. THE OUTCOME OF THIS AIM IS A CURATED DATASET THAT CAN BROADLY BENEFIT FUTURE TECHNICAL EFFORTS IN BREAST DIAGNOSIS. AIM 2 (DEEP LEARNING): TO MAKE RISK STRATIFICATION QUANTITATIVE WE PROPOSE TO ANALYZE THE MRI SCANS USING MODERN DEEP NETWORKS THAT HAVE BEEN TRAINED TO IDENTIFY THE LOCATION AND EXTENT OF A CANCER. WE WILL THEN TRANSFER THE MRI FEATURES OF THESE TRAINED NETWORKS AS WELL AS NETWORKS TRAINED ON MAMMOGRAMS TO THE TASK OF DIAGNOSIS AND RISK ASSESSMENT. THE INTENDED OUTCOME OF THIS AIM ARE PREDICTIVE MODELS WITH HUMAN-LEVEL PERFORMANCE AT DIAGNOSIS AND SEGMENTATION. AIM 3 (RISK ADJUSTED SCREENING): TO REDUCE THE BURDEN OF SCREENING WHILE MAINTAINING SENSITIVITY WE WILL ESTIMATE THE RISK OF FINDING A MALIGNANT TUMOR IN THE FUTURE, BASED ON THE PRESENT MRI EXAM AND MOST RECENT MAMMOGRAM AS WELL AS PATIENT INFORMATION. THE MACHINE-ESTIMATED RISK WILL BE USED IN A RETROSPECTIVE ANALYSIS TO DETERMINE THE PRIMARY OUTCOME, NAMELY, THE NUMBER OF EXAMS THAT COULD HAVE BEEN OMITTED BY SCHEDULING A LONGER SCREENING INTERVAL WITHOUT COMPROMISING SENSITIVITY. THIS WILL BE REPEATED ON NEWLY ACCRUED DATA AT MSK, DUKE AND JOHNS HOPKINS UNIVERSITY (JHU) AS SECONDARY SITES. ONCE VALIDATED, THE RISK-PREDICTION MODEL WILL BE PUBLICLY RELEASED TO ENCOURAGE DATA SHARING AND CLINICAL ADOPTION. THE PRELIMINARY WORK PERFORMED OVER THE LAST TWO YEARS HAS BROUGHT TOGETHER A UNIQUE INTERDISCIPLINARY TEAM INCLUDING CLINICAL INVESTIGATORS ON BREAST MRI AT MSK, AND MACHINE-LEARNING AND MEDICAL IMAGING EXPERTS AT CCNY, DUKE AND JHU. THE PLATFORM TECHNOLOGY THAT WILL BE DEVELOPED HERE IS APPLICABLE BEYOND BREAST CANCER, AND THE TRANSFER LEARNING APPROACH APPLICABLE IN PARTICULAR TO CANCERS WITH MORE LIMITED DATASETS.

DEVELOPING HISPANIC-SERVING INSTITUTIONS PROGRAM

STRENGTHENING THE SAFETY NET: TESTING A NOVEL DATA-TO-SUPPRESSION (D2S) INTERVENTION STRATEGY IN THE RYAN WHITE HIV/AIDS PROGRAM - ABSTRACT THE RYAN WHITE HIV/AIDS PROGRAM (RWHAP) FOR LOW-INCOME PEOPLE WITH HIV (PWH) IS A KEY RESOURCE FOR REDUCING HIV HEALTH DISPARITIES AND SCALING UP EVIDENCE-BASED INTERVENTIONS. AS RWHAP SERVES >50% OF US PWH, RWHAP OUTCOMES ARE VITAL TO ACHIEVING “GETTING TO ZERO”/ ENDING THE HIV EPIDEMIC (EHE) PLAN TARGETS. AS A GRANTEE FOR RWHAP PART A (RWPA) FUNDING DISTRIBUTED TO THE COUNTIES/CITIES SEVERELY AFFECTED BY HIV, NEW YORK CITY (NYC) CONDUCTS REGULAR HIV CARE CONTINUUM MONITORING CITYWIDE AND IN ITS RWPA PROGRAMS, WHICH OFFER SUPPORT SERVICES TO REDUCE SOCIAL AND BEHAVIORAL BARRIERS TO CARE/TREATMENT. LOCAL DATA CONSISTENTLY SHOW LOWER VIRAL SUPPRESSION (VS) AMONG RWPA CLIENTS IN HIV CARE THAN AMONG NON-RWPA PWH IN HIV CARE. RELATIVE TO NYC HIV CASES OVERALL, NYC RWPA CLIENTS (~14,000 PER YEAR) OVER-REPRESENT BLACK AND LATINX PWH AND HIGH-POVERTY NEIGHBORHOODS. TO ADDRESS LOCAL OUTCOME DISPARITIES AND TO FILL GAPS LEFT BY DATA-TO-CARE (D2C) STRATEGIES AND RESEARCH FOCUSED ON MEDICAL CARE (RE-)LINKAGE, WE PROPOSE TO IMPLEMENT AND RIGOROUSLY EVALUATE THE EFFECTIVENESS OF A NOVEL ‘DATA-TO-SUPPRESSION’ (D2S) INTERVENTION AMONG ~1,300 RWPA CLIENTS IN HIV CARE BUT UNSUPPRESSED. SURVEILLANCE-BASED REPORTS ON UNSUPPRESSED CLIENTS PLUS D2S CAPACITY-BUILDING ASSISTANCE WILL GUIDE RWPA PROVIDERS IN TARGETING AND DELIVERING EVIDENCE-INFORMED STRATEGIES TO IMPROVE VS. OUR PROPOSED AIMS ARE TO: 1) MEASURE D2S INTERVENTION EFFECTS ON TIMELY VS AND TIME TO VS, IN A STEPPED- WEDGE HYBRID TYPE 1 TRIAL; 2) IDENTIFY MODIFIABLE DETERMINANTS OF D2S RESPONSE, BY COMPARING CHARACTERISTICS OF D2S-EXPOSED CLIENTS WHO DO AND DO NOT ACHIEVE VS, TO RECOGNIZE OPPORTUNITIES TO TAILOR AND STRENGTHEN THE INTERVENTION; 3) ASSESS D2S ACCEPTABILITY AND PARTICIPANT PREFERENCES AND PRIORITIES FOR ITS IMPLEMENTATION, IN EIGHT (CLIENT AND PROVIDER) FOCUS GROUPS AND IN A DISCRETE CHOICE EXPERIMENT (DCE) WITH RWPA STAFF (N=200). THIS PROPOSAL ANSWERS THE CALL IN PAR-20-036 FOR RESEARCH TO DEEPEN UNDERSTANDING OF THE BROADER CONTEXT OF VS, BY LEVERAGING EXTENSIVE/MULTIPLE DATASETS AND RESOURCES AND APPLYING IMPLEMENTATION SCIENCE METHODS TO TEST AN INTERVENTION TO IMPROVE SERVICE DELIVERY AND ULTIMATELY ACHIEVE VS. THE STUDY IS ALSO ALIGNED WITH THE NATIONAL HIV/AIDS STRATEGY GOAL TO REDUCE HEALTH DISPARITIES – IN THIS CASE, A VS GAP BETWEEN RWPA CLIENTS IN CARE AND OTHER PWH IN CARE IN THE SAME JURISDICTION. THE PROPOSED STUDY’S HYBRID, TYPE 1 TRIAL DESIGN SUPPORTS RAPID DISSEMINATION AND UPTAKE BEYOND NYC, SHOULD THE INTERVENTION PROVE EFFECTIVE. THROUGH THE D2S TRIAL, ANALYSIS OF FACTORS DRIVING D2S RESPONSE, AND PRIMARY DATA COLLECTION IN NYC RWPA SUPPORT- SERVICE SETTINGS, THE PROJECT SEEKS TO CLARIFY FUTURE INTERVENTION DIRECTIONS FOR LOW-INCOME, BLACK AND LATINX PWH, WHOSE CARE CONTINUUM ADVANCES ARE VITAL FOR MEETING 90-90-90, “GETTING TO ZERO” AND EHE PLAN GOALS. THE PROJECT’S POTENTIAL IMPACT IS HEIGHTENED IN THE TIME OF COVID-19, GIVEN DISPROPORTIONATE BURDEN OF COVID- 19 AND RELATED RESTRICTIONS IN THE COMMUNITIES RWPA SERVES, AND NEW OBSTACLES TO CONTINUITY OF CARE/TREATMENT AND TO MAINTAINING CLOSE COMMUNICATION BETWEEN MEDICAL AND SUPPORT-SERVICE PROVIDERS ABOUT CLIENTS’ NEEDS.

STRENGTHENING INSTITUTIONS - HISPANIC SERVING INSTITUTIONS

IGERT--INTERDISCIPLINARY EVOLUTIONARY PRIMATOLOGY: CONSERVATION AND HUMAN EVOLUTION JOIN BEHAVIOR BONES AND GENES

MULTICOMPONENT INTERVENTION TO REDUCE SEXUAL RISK AND SUBSTANCE USE

RANDOMIZED TRIAL OF IFCBT-HIVPI TO PREVENT HIV AMONG NON-INJECTION DRUG USERS

NATIONAL INSTITUTE ON DISABILITY AND REHABILITATION RESEARCH - REHABILITATION RESEARCH AND TRAINING CENTERS

NYC LOUIS STOKES ALLIANCE

DEVELOPING HISPANIC-SERVING INSTITUTIONS PROGRAM

IMPROVING HIV AND ALCOHOL-RELATED OUTCOMES AMONG HIV+ PERSONS IN CLINIC SETTINGS

TRANSCRIPTIONAL REGULATION OF CONE PHOTORECEPTOR GENESIS

STRUCTURAL, MOLECULAR AND FUNCTIONAL SPECIALIZATION IN OSTEOCYTE MECHANOSENSING

BEHAVIORAL MECHANISMS OF VOCAL IMITATION

DOD CENTER FOR NANOSCALE PHOTONIC EMITTERS AND SENSORS FOR MILITARY, MEDICAL AND COMMERCIAL APPLICATIONS

MIND ALLIANCE FOR MINORITY STUDENTS WITH DISABILITIES IN SCIENCE, TECHNOLOGY, ENGINEERING AND MATHEMATICS

STRENGTHENING INSTITUTIONS - HISPANIC SERVING INSTITUTIONS

TAS::89 0336::TAS RECOVERY THE RESEARCH FOUNDATION CUNY-CITY COLLEGE WILL DEVELOP AN ELECTRICALLY INSULATING MATERIAL THAT INCREASES A CAPACITOR'S S

A RANDOMIZED INTERVENTION TRIAL TO INCREASE ACCESS TO REPRODUCTIVE HEALTH SERVICES AMONG ADOLESCENTS AND YOUNG ADULTS WITH INTELLECTUAL AND DEVELOPMENTAL DISABILITIES - PROJECT SUMMARY/ABSTRACT WE PROPOSE UPDATING, PILOTING AND TESTING A SOCIALIZATION AND SEX EDUCATION CURRICULUM (STEPS-2) DESIGNED FOR ADOLESCENTS AND YOUNG ADULTS WITH INTELLECTUAL AND DEVELOPMENTAL DISABILITIES (I/DD). WE WILL TEST THIS UPDATED CURRICULUM IN A RANDOMIZED CONTROLLED TRIAL (RCT) AMONG 856 ADOLESCENTS AND YOUNG ADULTS (AGED 18- 27 YEARS) WITH MILD TO MODERATE I/DD WHO RECEIVE SERVICES FROM DISABILITY PROVIDERS IN FOUR OF THE FIVE DEVELOPMENTAL DISABILITIES REGIONS OF THE NEW YORK STATE OFFICE FOR PEOPLE WITH DEVELOPMENTAL DISABILITIES. RANDOMIZATION WILL BE STRATIFIED BY REGION, SEX (MALE/FEMALE) AND AGE (18-22, 23-27). HALF OF THE PARTICIPANTS WILL BE RANDOMIZED TO RECEIVE THE UPDATED STEPS-2 SOCIALIZATION AND SEX EDUCATION CURRICULUM IN INDIVIDUALIZED SESSIONS DURING HOME VISITS, AND THE OTHER HALF WILL RECEIVE A GROUP-BASED INTERVENTION ON PHYSICAL EXERCISE AND NUTRITION IN A LOCAL COMMUNITY CENTER; ONLY ONE ROOMMATE WILL BE ELIGIBLE TO BE ENROLLED FROM ANY GROUP LIVING ARRANGEMENT TO MINIMIZE SPILLOVER EFFECTS. REGIONAL COORDINAT ORS WILL PROVIDE THE 6-WEEK LONG INTERVENTIONS, WITH INTERVIEW DATA COLLECTED AT BASELINE (PRIOR TO INTERVENTION), MONTH 2 (COMPLETION OF INTERVENTION), MONTH 6 AND MONTH 12. WE PROJECT COMPLETING RECRUITMENT INTO THE RCT DURING THE SECOND QUARTER OF YEAR 3, AND COMPLETION OF MONTH 12 ASSESSMENTS IN THE THIRD QUARTER OF YEAR 4. THE PRIMARY OUTCOME WILL BE PROPORTION OF PARTICIPANTS REPORTING HAVING HAD A CONVERSATION ABOUT SEX/REPRODUCTIVE HEALTH WITH A MEDICAL PROVIDER BY MONTH 12, WITH SECONDARY OUTCOMES INCLUDING HPV VACCINATION STATUS, RECEIPT OF SEX AND AGE-SPECIFIC PREVENTIVE HEALTH SCREENING, SOCIAL SEXUAL BEHAVIORS, AGENCY OVER DECISIONS, AND, AMONG THOSE SEXUALLY ACTIVE, USE OF CONTRACEPTION (IF NOT DESIRING A PREGNANCY), AND USE OF SEXUALLY TRANSMITTED INFECTION/HIV PROTECTION. INTERIM MEASURES WILL BE USED TO ASSESS KNOWLEDGE AND TO REDUCE THE LIKELIHOOD OF RECALL BIAS FOR THE PRIMARY ENDPOINT. SPECIFICALLY, WE AIM TO: (1) UPDATE AND PILOT AN EXISTING SOCIALIZATION AND SEX EDUCATION CURRICULUM (STEPS-2) FOR 18-27 YEAR OLDS WITH I/DD IN NEW YORK STATE THROUGH A PARTICIPATORY PROCESS CENTERING THE VOICES OF DIVERSE LIVED EXPERIENCES; (2) TEST THE EFFICACY OF THIS SOCIALIZATION AND SEX EDUCATION CURRICULUM IN A RANDOMIZED INTERVENTION TRIAL USING INTENTION-TO-TREAT AND INSTRUMENTAL VARIABLE ANALYSES TO ADJUST FOR COMPLIANCE. WE HYPOTHESIZE THAT AT LEAST AN ADDITIONAL 10% OF THE INDIVIDUALS IN THE EXPERIMENTAL GROUP WILL HAVE HAD A REPRODUCTIVE HEALTH DISCUSSION WITH A MEDICAL PROVIDER BY MONTH 12 COMPARED WITH THE CONTROL GROUP; AND (3) TEST WHETHER THE EFFICACY OF THE INTERVENTION DIFFERS BY SEX AND AGE IN STRATIFIED ANALYSES. WE HAVE POWERED THE STUDY FOR SEX-SPECIFIC EFFICACY ESTIMATES AND WILL EXPLORE WHETHER EFFICACY DIFFERS BY AGE. THE FINDINGS FROM THIS TRANSLATIONAL STUDY WILL INFORM PRACTITIONERS, ADVOCATES, AND SELF-ADVOCATES ABOUT BEST PRACTICES FOR REPRODUCTIVE AND SEXUAL HEALTH EDUCATION FOR ADOLESCENTS AND YOUNG ADULTS WITH I/DD AS THEY TRANSITION TO ADULTHOOD.

STRENGTHENING INSTITUTIONS - HISPANIC SERVING INSTITUTIONS

TAS::89 0321::TAS 260.10 CDP, NEW AWARD

DEVELOPING HISPANIC-SERVING INSTITUTIONS PROGRAM

HIV CARE COORDINATION: COMPARATIVE EFFECTIVENESS, OUTCOME DETERMINANTS AND COSTS

IMPACT OF PARK RENOVATIONS ON PHYSICAL ACTIVITY AND COMMUNITY HEALTH IN NYC

TRADE ADJUSTMENT ASSISTANCE COMMUNITY COLLEGE AND CAREER TRAINING

COMMUNITY HEALTH WORKER TRAINING PROGRAM - PROJECT ABSTRACT ADDRESS: HOSTOS COMMUNITY COLLEGE, CUNY DIVISION OF CONTINUING EDUCATION & WORKFORCE DEVELOPMENT (CEWD) C/O RESEARCH FOUNDATION OF CUNY 475 GRAND CONCOURSE, ROOM A-339B, BRONX, NY 10451 PROJECT DIRECTOR NAME: EVELYN FERNANDEZ-KETCHAM, PH.D., LCSW, VICE PRESIDENT CONTACT: PHONE: 718-518-6646 EMAIL: EFERNANDEZ-KETCHAM@HOSTOS.CUNY.EDU ACCORDING TO DATA FROM EMSI BURNING GLASS (2022) THERE WERE OVER 1,000 UNIQUE JOB POSTINGS FOR COMMUNITY HEALTH WORKERS (CHWS) IN NEW YORK CITY OVER THE LAST DECADE (JANUARY 2010-FEBRUARY 2022). THIS AVERAGES OUT TO AROUND 8 JOB POSTINGS PER MONTH. HOWEVER, THE NUMBER OF COMMUNITY HEALTH WORKERS ACTUALLY HIRED WAS MUCH HIGHER THAN JOBS POSTED, WITH AN AVERAGE OF 185 MONTHLY HIRES IN THE SAME PERIOD. THE MEDIAN ANNUAL SALARY LISTED ON JOB POSTINGS FOR COMMUNITY HEALTH WORKER IS $44,4000; HOWEVER, THIS IS $1,100 BELOW THE GOVERNMENT RECORDED MEDIAN SALARY FOR THE NEW YORK METROPOLITAN AREA, SO JOB SEEKERS CAN EXPECT TO EARN MORE. IN THE NEXT DECADE, IT IS PROJECTED THAT THERE WILL BE AN INCREASE OF 19 PERCENT IN THE NUMBER OF JOBS AVAILABLE FOR COMMUNITY HEALTH WORKERS WITH A PROJECTION OF ABOUT 186 MONTHLY HIRES. BY 2025 WE AIM TO RECRUIT UP TO 360 CHW CANDIDATES IN ORDER TO TRAIN AND/OR UPSKILL 270 (18 COHORTS OF UP TO 15 STUDENTS) COMMUNITY HEALTH WORKER (75% NEW WORKERS AND 25% LOOKING TO UPSKILL); OF TRAINEES THAT COMPLETE, 203 (75%) WILL RECEIVE A FIELD PLACEMENT AND 51 (25% OF THE 203) WILL PARTICIPATE IN AN APPRENTICESHIP PROGRAM; IN ADDITION, WE ANTICIPATE EACH YEAR, 18 STUDENTS WILL TRANSITION/MATRICULATE AT HOSTOS WITH COLLEGE CREDITS USING CREDIT FOR PRIOR LEARNING (CPL). THE LONG-TERM GOAL IS TO INCREASE THE NUMBER OF TRAINED/SKILLED COMMUNITY HEALTH WORKERS LOCALLY AND REGIONALLY; AND ULTIMATELY CREATE AN INDUSTRY “GOLD STANDARD” TRAINING MODEL FOR CHW. THE HOSTOS COMMUNITY HEALTH WORKER TRAINING AND REGISTERED APPRENTICESHIP PROVIDES MULTIPLE ENTRY AND EXIT POINTS FOR STUDENTS TO ENGAGE WITH THE CHW OCCUPATIONAL FIELD: 1) NOVICE WORKERS CAN USE THE CHW TRAINING TO OBTAIN A BASELINE OF KNOWLEDGE AND GAIN ENTRY INTO A COMMUNITY HEALTH JOB, WHERE THERE IS OPPORTUNITY TO RECEIVE MORE EXTENSIVE TRAINING THROUGH THE REGISTERED APPRENTICESHIP; 2) INCUMBENT WORKERS OR WORKERS WHO HAVE OTHER CERTIFICATIONS IN THE HEALTHCARE FIELD CAN UTILIZE THE TRAINING TO UPSKILL/RETOOL AND ENTER INTO A HIGHER PAYING TITLE IN THE FIELD; 3) WORKERS LOOKING TO OBTAIN A COLLEGE DEGREE CAN LEVERAGE THE CERTIFICATE TOWARDS AN ASSOCIATE’S DEGREE IN COMMUNITY HEALTH; AND 4) SUPERVISORS, OR CHWS WITH SEVERAL YEARS OF EXPERIENCE LOOKING TO BECOME SUPERVISORS, CAN TAKE THE “TRAIN-THE-TRAINER’ COURSE TO UPSKILL. HOSTOS COMMUNITY COLLEGE/CONTINUING EDUCATION AND WORKFORCE DEVELOPMENT (CEWD) IS NOT REQUESTING FUNDING PREFERENCE. THE TOTAL FUNDING AMOUNT REQUESTED IS $3,000,000 FOR THREE YEARS TO EXPAND THE HOSTOS COMMUNITY HEALTH WORKER TRAINING PROGRAM.

PREDOMINANTLY BLACK INSTITUTIONS

BRONX COMMUNITY COLLEGE SEEKS TO ALIGN CAMPUS PRACTICES BASED ON VALIDATED ASAP STRATEGIES TO SUPPORT THE RETENTION, GRADUATION, AND TRANSFER RATES OF HISPANIC STUDENTS.

SYSTEMS-BASED DESIGN OF BIOMOLECULAR MODALITIES AND MATERIALS

MULTI-PHYSICS METAMATERIALS FOR THERMAL MANAGEMENT AND HEAT MANIPULATION

HISPANIC SERVING INSTITUTIONS STEM HUB FOR INNOVATION IN NUMERACY EDUCATION (HSI-SHINE) -WITH SUPPORT FROM THE IMPROVING UNDERGRADUATE STEM EDUCATION: HISPANIC-SERVING INSTITUTIONS (HSI PROGRAM), THIS HSI PROGRAM RESOURCE HUB AIMS TO IMPROVE STUDENTS' NUMERACY SKILLS, TRAIN FACULTY AT HISPANIC-SERVING INSTITUTIONS TO TEACH THESE SKILLS MORE EFFECTIVELY AND DEVELOP A NATIONAL REPOSITORY OF NUMERACY RESOURCES FOR FACULTY AND STUDENTS AT HSIS. THE STEM HUB FOR INNOVATION IN NUMERACY EDUCATION (SHINE) WILL ADDRESS WIDESPREAD ILLITERACY IN QUANTITATIVE SKILLS BY EQUIPPING FACULTY WITH PROFESSIONAL DEVELOPMENT IN TEACHING QUANTITATIVE REASONING AND DATA ANALYSIS, DEVELOPING AN ENGAGING ONLINE NUMERACY TRAINING PLATFORM, AND ESTABLISHING COMMUNITY-BASED DATA ANALYSIS RESEARCH PROGRAMS (DARP) THAT APPLY QUANTITATIVE RESEARCH SKILLS TO REAL-WORLD PROBLEMS. SHINE WILL ALSO INTEGRATE CO-REQUISITE MATH INSTRUCTION AND CREATE A REPOSITORY OF RESOURCES CONNECTING STUDENTS WITH INTERNSHIPS, JOB OPPORTUNITIES, AND EDUCATIONAL PATHWAYS. FACULTY PARTICIPANTS WILL DESIGN INNOVATIVE INSTRUCTIONAL MATERIALS, MENTOR STUDENTS IN MEANINGFUL RESEARCH PROJECTS, AND IMPLEMENT EVIDENCE-BASED APPROACHES TO STRENGTHEN NUMERACY EDUCATION. THESE EFFORTS AIM TO BUILD SUSTAINABLE COMMUNITIES OF PRACTICE THAT PROMOTE COLLABORATION AMONG FACULTY AND INSTITUTIONS, IMPROVE EDUCATIONAL OUTCOMES FOR STUDENTS, AND PREPARE PARTICIPANTS FOR SUCCESSFUL CAREERS IN STEM. BY ADDRESSING THE NEEDS OF BOTH STUDENTS AND SURROUNDING COMMUNITIES, SHINE WILL CREATE A LASTING EDUCATIONAL AND SOCIETAL IMPACT, BRIDGING GAPS IN NUMERACY EDUCATION. THE SHINE PROJECT AIMS TO STRENGTHEN FACULTY CAPACITY FOR TEACHING QUANTITATIVE REASONING AND DATA ANALYSIS WHILE IMPROVING STUDENTS? NUMERACY SKILLS WITHIN THE LARGER PROCESS OF LIBERATORY IDENTITY DEVELOPMENT, INCLUDING NOT ONLY ACADEMIC (STEM IDENTITY, IN PARTICULAR) VIS A VIS COMMUNITY-BASED INITIATIVES. PARTICIPANTS WILL DEVELOP INSTRUCTIONAL MATERIALS, LEAD STUDENT ASSESSMENTS, AND MENTOR STUDENTS IN THE DARP, WHICH CONNECTS CLASSROOM LEARNING TO REAL-WORLD APPLICATIONS. THE PROJECT WILL ALSO LAUNCH AN ONLINE NUMERACY TRAINING PLATFORM WITH ACCESSIBLE FEATURES AND CO-REQUISITE MATHEMATICAL SUPPORT, PROVIDING STUDENTS WITH EFFECTIVE TOOLS FOR SKILL DEVELOPMENT. SHINE WILL EVALUATE ITS IMPACT THROUGH A MIXED-METHODS APPROACH, INCLUDING SURVEYS, SKILLS TESTS, INTERVIEWS, AND FOCUS GROUPS, TO MEASURE FACULTY PREPAREDNESS AND STUDENT QUANTITATIVE REASONING SKILLS, STEM IDENTITY, AND LIBERATORY OUTCOMES. KEY RESEARCH QUESTIONS WILL ADDRESS HOW SHINE BUILDS EMPOWERING OUTCOMES BY INFLUENCING COGNITIVE SKILLS, ATTITUDES, STUDENT RETENTION, GRADUATION RATES, AND CAREER TRAJECTORIES. ANTICIPATED OUTCOMES INCLUDE ENHANCED FACULTY EXPERTISE, IMPROVED STUDENT NUMERACY AND STEM READINESS, AND A NATIONAL REPOSITORY OF INSTRUCTIONAL RESOURCES TO SUPPORT QUANTITATIVE REASONING EDUCATION ACROSS INSTITUTIONS. DISSEMINATION OF FINDINGS WILL OCCUR THROUGH SCHOLARLY ARTICLES, CONFERENCE PRESENTATIONS, AND OPEN-ACCESS MATERIALS, ENSURING SCALABILITY AND BROAD IMPACT. THE HSI PROGRAM AIMS TO ENHANCE UNDERGRADUATE STEM EDUCATION AND BUILD CAPACITY AT HSIS. PROJECTS SUPPORTED BY THE HSI PROGRAM WILL ALSO GENERATE NEW KNOWLEDGE ON HOW TO ACHIEVE THESE AIMS. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE PLANNED FOR THIS AWARD.

NANOSCIENCE CONNECTED TO LIFE: AN INTERDISCIPLINARY TRAINEESHIP PROGRAM IN BIOINSPIRED NANOTECHNOLOGY -THE LIVING WORLD PROVIDES MANY FASCINATING EXAMPLES OF HIGHLY EVOLVED, SOPHISTICATED MACHINERY WORKING IN SYNERGY TO SUSTAIN LIFE. A FUNDAMENTAL UNDERSTANDING OF NATURE?S ARCHITECTURES AND PROCESSES CAN BE APPLIED TO CREATE NEW BIOLOGY-INSPIRED AND GREEN TECHNOLOGIES FOR THE BENEFIT OF HUMAN AND ENVIRONMENTAL HEALTH. HOWEVER, THIS CHALLENGING TASK REQUIRES INTEGRATING ASPECTS OF RESEARCH IN BIOLOGY, CHEMISTRY, AND PHYSICS FOCUSED DOWN TO THE SMALLEST FUNCTIONAL SCALE: THE NANOSCALE. THIS NSF RESEARCH TRAINEESHIP (NRT), NANOSCIENCE CONNECTED TO LIFE: AN INTERDISCIPLINARY TRAINEESHIP PROGRAM IN BIOINSPIRED NANOTECHNOLOGY, WILL PROVIDE EDUCATION, RESEARCH, AND CAREER DEVELOPMENT TO HELP BUILD A NEW WORKFORCE IN THE EMERGING FIELD OF BIOINSPIRED NANOTECHNOLOGY. AS THIS FIELD UNDERGOES RAPID EXPANSION AND INDUSTRY EMBRACES THESE NEW APPROACHES, SOCIETY NEEDS A UNIQUELY TRAINED AND DIVERSE WORKFORCE. BUILDING ON THE CITY UNIVERSITY OF NEW YORK?S (CUNY) REPUTATION AS AN ENGINE FOR UPWARD MOBILITY OF A DIVERSE STUDENT POPULATION, THIS TRAINEESHIP WILL PROVIDE A NOVEL AND COMPREHENSIVE GRADUATE EDUCATION FOR 125 GRADUATE STUDENTS. THE PROGRAM WILL SERVE 25 DIRECTLY FUNDED TRAINEES, INCLUDING INDIVIDUALS FROM MINORITY POPULATIONS UNDERREPRESENTED IN THEIR PURSUIT OF STEM FIELDS OF STUDY, WOMEN, AND MEMBERS OF THE LGBTQ+ COMMUNITY. GRADUATES WILL BECOME EFFECTIVE LEADERS WHO WILL BE ABLE TO SOLVE COMPLEX PROBLEMS FACING THE U.S. AND PROVIDE NEW SCIENTIFIC BREAKTHROUGHS IN ENERGY HARVESTING, AGRICULTURE, MEDICINE, AND ENVIRONMENTAL REMEDIATION. THE BROAD EDUCATIONAL VISION OF THIS PROJECT IS TO TRAIN A GENERATION OF STEM PH.D. STUDENTS AS COLLABORATIVE, SYSTEMS-LEVEL THINKERS WHO CAN TRANSLATE CONCEPTS ACROSS SCALES AND DISCIPLINES. THE PROJECT STRENGTHENS AND INTEGRATES CHEMISTRY, BIOCHEMISTRY, AND PHYSICS PH.D. PROGRAMS AT CUNY THROUGH CONVERGENCE AROUND COMMON GOALS. STUDENTS WILL BECOME WELL-POSITIONED TO WORK ON CONVERGENT TEAMS TO ADDRESS URGENT SOCIETAL CHALLENGES RELATED TO ENVIRONMENTAL INSTABILITIES AND HEALTH CRISES. AT THE HEART OF EACH STUDENT?S EXPERIENCE IS A USE-INSPIRED PROJECT IN ONE OF SEVERAL DIFFERENT AREAS OF RESEARCH EMPLOYING BIOLOGY-INSPIRED APPROACHES. THESE INCLUDE: I) HARVESTING AND CONVERSION OF ENERGY, II) DESIGNING NANOSCALE INTERFACES TO MEASURE AND INFLUENCE LIVING SYSTEMS, III) NEWLY DESIGNED SUSTAINABLE GREEN MATERIALS, AND IV) DEVELOPMENT OF ADAPTIVE METABOLIC SYSTEMS AND FUNCTIONAL MATERIALS FOR THERAPEUTIC AND INDUSTRIAL USE. THESE INVESTIGATIONS WILL SPAN THEORETICAL, COMPUTATIONAL, AND EXPERIMENTAL APPROACHES. THE PROJECT WILL PREPARE CUNY PH.D. STUDENTS FOR STEM CAREERS IN INDUSTRIAL, GOVERNMENT, ACADEMIC, AND ENTREPRENEURIAL TRACKS BY INTEGRATING CAREER AWARENESS THROUGHOUT THE TRAINING PERIOD. THE TRAINING PLAN IS BASED ON AN INNOVATIVE INTEGRATING MENTAL MODELS AND EXPERIMENTAL RESEARCH IN SCIENTIFIC EDUCATION (IMMERSE) TRAINING MODEL, DESIGNED?TO?CREATE A LEARNING COMMUNITY OF SYSTEMS THINKERS. IN THIS MODEL, PARTICIPANTS EXCHANGE KNOWLEDGE AND COMMUNICATE ACROSS UNFAMILIAR CONCEPTS, CULTURES, AND METHODS. THE IMMERSE TRAINING MODEL CAN BE REPLICATED AT OTHER UNIVERSITIES AND IN OTHER CONVERGENT RESEARCH AREAS. THE NSF RESEARCH TRAINEESHIP (NRT) PROGRAM IS DESIGNED TO ENCOURAGE THE DEVELOPMENT AND IMPLEMENTATION OF BOLD, NEW POTENTIALLY TRANSFORMATIVE MODELS FOR STEM GRADUATE EDUCATION TRAINING. THE PROGRAM IS DEDICATED TO EFFECTIVE TRAINING OF STEM GRADUATE STUDENTS IN HIGH PRIORITY INTERDISCIPLINARY OR CONVERGENT RESEARCH AREAS THROUGH COMPREHENSIVE TRAINEESHIP MODELS THAT ARE INNOVATIVE, EVIDENCE-BASED, AND ALIGNED WITH CHANGING WORKFORCE AND RESEARCH NEEDS.? THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

PREM: CITY COLLEGE-CHICAGO MRSEC PARTNERSHIP ON THE DYNAMICS OF HETEROGENEOUS AND PARTICULATE MATERIALS

NEW, GK-12 BROOKLYN COLLEGE -- CITY AS LAB

BMCC'S CONEXIÓNES PROJECT WILL DEVELOPED A SINGLE COMPREHENSIVE ACTIVITY INTENDED TO IMPROVE STUDENT SUCCESS AMONG LATINO MALE AND OTHER LOW-INCOME STUDENTS BEYOND THE FIRST YEAR OF STUDY.

RAMP: DIVERSIFYING THE NATIONAL BIOLOGY WORKFORCE THROUGH NEW YORK TRANSDISCIPLINARY BIOSCIENCES (NY-RAMP) -MENTORING THE NEXT GENERATION OF A DIVERSE SCIENTIFIC WORKFORCE IS CRITICAL TO ACCELERATE INNOVATIVE SCIENCE AND PROMOTE A POSITIVE NATIONAL FUTURE. THE RESEARCH NETWORK IN NEW YORK COMBINES TRANS-DISCIPLINARY BIOSCIENCES ACROSS ACADEMIA, INDUSTRY, AND RESEARCH INSTITUTES WITH MANY CREATIVE MINDS AND A TALENTED WORKFORCE, HOWEVER SENIOR POSITIONS TYPICALLY LACK DIVERSITY. RESEARCH PROFESSORS AND TRAINED EDUCATORS OF THE HUNTER COLLEGE BELFER RESEARCH ALLIANCE WILL LEAD THE NEW YORK RESEARCH AND MENTORING FOR POSTBACCALAUREATES IN BIOLOGICAL SCIENCES (NY-RAMP) TRANS-DISCIPLINARY PROGRAM. THE MENTORING TEAM OF NY-RAMP WILL PROVIDE RESEARCH AND PROFESSIONAL DEVELOPMENT OPPORTUNITIES TO LAUNCH THE CAREERS OF RECENT SCIENCE GRADUATES LACKING RESEARCH EXPERIENCE. THE NY-RAMP PROGRAM WILL PROVIDE HIGH-IMPACT RESEARCH IMMERSION AND EDUCATION IN TRANS-DISCIPLINARY CELL, MOLECULAR, AND BIOINFORMATICS, WITH A FOCUS ON DISCOVERY SCIENCE. THE IMMERSION EXPERIENCES ARE FOR INQUISITIVE RECENT GRADUATES WHO HAVE LIMITED RESEARCH EXPERIENCE. THIS PROGRAM WILL ENABLE THE SELECTED EMERGING SCHOLARS TO BE TRAINED BY RESEARCH PROFESSORS ACTIVELY INVOLVED IN COLLABORATIVE CELL SIGNALING RESEARCH. IMPORTANTLY, NY-RAMP WILL WORK TO PROVIDE THE NATION WITH A MUCH-NEEDED DIVERSE TRANS-DISCIPLINARY BIOLOGY TRAINED WORKFORCE. THE NY-RAMP PROGRAM PROVIDES ONE-YEAR BIOLOGY RESEARCH EXPERIENCES FOR THREE COHORTS OF TEN RECENT GRADUATES UNDER THE UMBRELLA THEME OF TRANS-DISCIPLINARY EXPERIMENTAL, COMPUTATIONAL, AND APPLIED BIOSCIENCES TO INVESTIGATE CELLULAR SIGNALING. CROSS-DEPARTMENTAL CITY UNIVERSITY OF NEW YORK (CUNY) HUNTER COLLEGE PROFESSORS SERVE AS THE PRINCIPAL INVESTIGATOR (PI), THE COORDINATOR AND CO-PIS, AND THE MENTORS, IN COLLABORATION WITH CO-MENTORING TEAMS FROM OTHER NEW YORK STATE INSTITUTIONS. TOGETHER THESE TRANS-DISCIPLINARY SCIENTISTS BRIDGE THE DIVERSITY OF PEOPLE AND SCIENCE THAT NEW YORK HAS TO OFFER IN SCHOLARSHIP AND WORKFORCE DEVELOPMENT. THE PROGRAM ENCOURAGES EMERGING SCHOLARS TO BECOME BIOLOGICAL THINKERS AND DEVELOP INTO SCIENTISTS. THE NY-RAMP CONNECTS THE SELECTED EMERGING SCHOLARS TO THE CUNY BROOKLYN-BASED COLD SPRING HARBOR LABORATORY (CSHL) DNA LEARNING CENTER FOR MOLECULAR BIOLOGY AND GENE-BASED ORIENTATION BOOT-CAMP (IN ADDITION TO FOLLOW-UP FIELD TRIPS), TO STATE UNIVERSITY OF NEW YORK?S (SUNY?S) LEADERSHIP AND CAMPUSES, TO THE SKIRBALL SCIENCE LEARNING CENTER (AT HUNTER COLLEGE), TO THE CORNELL CENTER FOR CULTURAL HUMILITY, TO ACTIVE NY BIOLOGY INDUSTRY FIELD TRIPS, AND TO VISITS TO NY-AREA COLLEGES AND UNIVERSITIES. THIS TRANS-DISCIPLINARY INQUIRY FOCUSED PROGRAM IS DESIGNED FOR ENGAGED COLLABORATIVE DISCOVERY-SCIENCE FOR MENTORS AND MENTEES TO GAIN DEEP UNDERSTANDINGS OF CELLULAR SIGNALING IN A DIVERSE COMPREHENSIVE ENVIRONMENT. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

IGERT: RETURNING THE RADIO TO CHEMISTRY: INTEGRATING RADIOCHEMISTRY INTO A CHEMISTRY PH.D. PROGRAM

RAMP: ON-RAMP TO THE MOLECULAR MACHINE SHOP: POSTBACCALAUREATE TRAINING IN BIOCHEMISTRY, BIOPHYSICS, AND BIODESIGN -THIS AWARD IS FUNDED IN PART UNDER THE AMERICAN RESCUE PLAN ACT OF 2021 (PUBLIC LAW 117-2). ATTRACTING TALENTED WOMEN AND MEN TO SCIENCE, TECHNOLOGY, ENGINEERING AND MATHEMATICS (STEM) FIELDS REMAINS A PRIORITY FOR STEM-FOCUSED ACADEMIC DEPARTMENTS IN THE UNITED STATES. THIS IMPERATIVE IS UNDERSCORED BY THE CRUCIAL ROLES OF STEM PROFESSIONALS, DIRECTLY OR INDIRECTLY, IN THE US ECONOMY. ENTRY INTO THE LUCRATIVE STEM PROFESSIONS REQUIRES HIGH DEGREES OF SKILL; ADVANCEMENT REQUIRES A BACHELOR'S DEGREE, OFTEN WITH ADDITIONAL DEGREES AND CERTIFICATIONS. NOTABLY, CURRENT DEMOGRAPHIC DISPARITIES IN US STEM PROFESSIONALS IMPLY THAT DIVERSE HUMAN TALENT IS BEING 'LEFT ON THE TABLE.' TO ATTRACT MORE WOMEN AND MEN TO STEM, CITY COLLEGE OF NEW YORK (CCNY) WILL ESTABLISH A REGIONAL RESEARCH TRAINING NETWORK ENTITLED ?ON-RAMP TO THE MOLECULAR MACHINE SHOP: POSTBACCALAUREATE TRAINING IN BIOCHEMISTRY, BIOPHYSICS, AND BIODESIGN (RAMMMP).? THE NETWORK WILL FOSTER ENTRY OF A DIVERSE CADRE OF RECENT BACHELOR?S DEGREE GRADUATES INTO CAREERS IN DEMANDING SCIENTIFIC FIELDS SUCH AS BIOTECHNOLOGY, BIOENGINEERING, AND SCIENCE EDUCATION, AMONGST OTHERS. THE NETWORK WILL ENCOMPASS MEMBERS OF THE CCNY FACULTY, EXTERNAL COLLABORATORS, TECHNOLOGY AND PROFESSIONAL TRAINING SPECIALISTS, COLLEGE SCIENCE DEPARTMENT CHAIRS, AND CURRENT PRACTITIONERS OF DIVERSE SCIENCE-RELATED OCCUPATIONS WHO WILL ACT AS MENTORS AND CO-MENTORS TO THREE COHORTS OF 12 POSTBACCALAUREATE STUDENTS EACH. EMBEDDED LABORATORY EXPERIENCES, SUPPLEMENTED BY PROFESSIONAL DEVELOPMENT WORKSHOPS AND BROAD-BASED CAREER EXPLORATION ACTIVITIES, WILL PREPARE EACH COHORT FOR REWARDING CAREERS IN STEM DISCIPLINES. THE BROADER IMPACTS OF THE PROJECT WILL INCLUDE: 1) MITIGATING GENDER, RACIAL, ETHNIC, AND ECONOMIC DISPARITIES IN THE STEM WORKFORCE; AND 2) PRODUCING AN EDUCATED CITIZENRY WITH THE KNOW-HOW TO MEET THE SOCIETAL CHALLENGES OF TECHNICALLY COMPLEX ENERGY, ENVIRONMENTAL, AND HEALTH ISSUES. THE HEART OF THE RAMMMP PROGRAM WILL BE AN IMMERSIVE MENTORED RESEARCH EXPERIENCE, ENRICHED BY PROFESSIONAL DEVELOPMENT ACTIVITIES AND A STIMULATING COMMUNITY. TO ENSURE ROBUST PARTICIPATION OF BOTH STUDENT MENTEES AND THEIR FACULTY MENTORS IN THE PROGRAM, A THREE-MODULE PLAN TERMED 1) GETTING READY, 2) GETTING SET, AND 3) GETTING GOING WILL BE IMPLEMENTED. DURING THE GETTING READY PHASE OF THE PLAN, THE FACULTY GROUP WILL PARTICIPATE IN A MENTOR TRAINING WORKSHOP, INCOMING TRAINEES WILL UNDERGO A 10-SESSION RESEARCH IDENTITY BOOTCAMP, AND MENTOR-MENTEE PARTNERSHIPS WILL BEGIN TO TAKE SHAPE. THE GETTING SET STAGE OF THE PLAN WILL CENTER ON BUILDING TECHNICAL SKILLS OF TRAINEES, PURSUING SCIENTIFIC RESEARCH PROJECTS, DEVELOPING COHORTS, AND ENHANCING COMMUNICATION SKILLS. FINALLY, THE GETTING GOING PHASE WILL FOCUS ON PATHWAYS TO STEM PROFESSIONS, PRESENTATIONS ON THE DIVERSITY OF STEM CAREERS, AND SAMPLING OF DIVERSE EMPLOYMENT SECTORS. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

ACHIEVING EQUITABLE PERSISTENCE IN STEM WITH A DATA-INFORMED STUDENT-CENTERED TRANSFORMATION OF THE FIRST-YEAR COLLEGE EXPERIENCE

CELL CYCLE REGULATION IN RESPONSE TO PLASMA MEMBRANE STRESS IN S. CEREVISAE

LAGUARDIA BRIDGES TO THE BACCALAUREATE

THE CUNY SCIENCE NOW GK-12 PROGRAM

COMMUNITY HEALTH WORKER TRAINING PROGRAM - COMMUNITY HEALTH WORKER TALENT PIPELINE INITIATIVE, LAGUARDIA COMMUNITY COLLEGE 29-10 THOMSON AVENUE, LONG ISLAND CITY, NY 11101 HANNAH WEINSTOCK, 718-482-5285 HWEINSTOCK@LAGCC.CUNY.EDU WWW.LAGUARDIA.EDU GRANT PROGRAM FUNDS REQUESTED: $2,992,528.86 REQUESTING FUNDING PREFERENCE LAGUARDIA COMMUNITY COLLEGE (LAGUARDIA) PROPOSES THE COMMUNITY HEALTH WORKER (CHW) TALENT PIPELINE INITIATIVE TO: - EXPAND THE PUBLIC HEALTH WORKFORCE BY TRAINING COMMUNITIES FACING HEALTH DISPARITIES TO SERVE AS COMMUNITY HEALTH WORKERS - STRENGTHEN THE SKILLS OF CURRENT COMMUNITY HEALTH WORKERS SO THAT THEY CAN MORE EFFECTIVELY SERVE THEIR COMMUNITIES. THIS APPROACH IS GROUNDED IN THE EVIDENCE-BASED ASSUMPTION THAT TRAINING COMMUNITIES FACING HEALTH DISPARITIES TO SERVE AS COMMUNITY HEALTH WORKERS WILL FOSTER ECONOMIC MOBILITY, INCREASE ACCESS TO CARE AND QUALITY OF CARE, AND HELP CLOSE HEALTH DISPARITIES. LAGUARDIA WILL RECRUIT LOW-INCOME, UNEMPLOYED AND UNDEREMPLOYED NEW YORKERS FOR CHW TRAINING AND EMPLOYMENT, WITH A FOCUS ON THE FOLLOWING THREE POPULATIONS EXPERIENCING HEALTH DISPARITIES: - PUBLIC HOUSING RESIDENTS - IMMIGRANTS WITH LIMITED ENGLISH PROFICIENCY - COMMUNITIES OF COLOR IN NYC’S HIGHEST-POVERTY NEIGHBORHOODS THIS WILL BE ACCOMPLISHED THROUGH PARTNERSHIPS WITH THE FOLLOWING THREE ORGANIZATIONS: - NYC HOUSING AUTHORITY RESIDENT ECONOMIC EMPOWERMENT & SUSTAINABILITY (NYCHA REES) WILL HELP TO RECRUIT PUBLIC HOUSING RESIDENTS FOR ALL FOUR TRAINING TRACKS. - COMMONPOINT QUEENS (CPQ) WILL HELP TO RECRUIT ENGLISH LANGUAGE LEARNERS AND TO OFFER CONTEXTUALIZED ENGLISH LANGUAGE BRIDGE INSTRUCTION SIMULTANEOUS TO THE CHW TRAINING. - 1199SEIU TRAINING AND EMPLOYMENT FUNDS (1199) WILL SPONSOR THE CHW REGISTERED APPRENTICESHIP, MANAGE THE RELATIONSHIP WITH THE APPRENTICESHIP EMPLOYER, AND TRAIN INCUMBENT WORKERS. OVER THE COURSE OF THREE YEARS, LAGUARDIA WILL TRAIN 255 STUDENTS, INCLUDING 195 JOB-SEEKERS AND 60 INCUMBENT WORKERS, ACROSS FOUR DIFFERENT TRAINING T RACKS: TRACK A: STANDARD CHW TRAINING AND INTERNSHIP PROGRAM TRACK B: CHW FOR ENGLISH LANGUAGE LEARNERS TRAINING AND INTERNSHIP PROGRAM TRACK C: CHW REGISTERED APPRENTICESHIP PROGRAM TRACK D: CHW INCUMBENT WORKER TRAINING LAGUARDIA’S CHW TRAINING CURRICULUM INCLUDES FOUR CLASSES, DELIVERED OVER 200 HOURS OF INSTRUCTION: FOUNDATIONS OF COMMUNITY HEALTH WORK, PUBLIC HEALTH, HEALTH & WELLNESS, AND TECHNOLOGY FOR COMMUNITY HEALTH. TOPICS INCLUDE MOTIVATIONAL INTERVIEWING, ACTIVE LISTENING, INTER-PERSON AND COMMUNICATION SKILLS, INTER-DISCIPLINARY TEAMS, OUTREACH AND ENGAGEMENT, ADVOCACY, SERVICE COORDINATION, HEALTHCARE AND SOCIAL SERVICE SYSTEMS, HEALTH INSURANCE, CULTURAL COMPETENCE, RACISM, SOCIAL DETERMINANTS OF HEALTH, POPULATION HEALTH, CHRONIC DISEASES, INFECTIOUS DISEASES, MENTAL HEALTH, SUBSTANCE USE, DIET, EXERCISE, SEXUALITY, MICROSOFT OFFICE SUITE, TELEHEALTH, ELECTRONIC HEALTH RECORDS, AND MORE. THE COURSES CARRY NINE CREDITS FOR THOSE CONTINUING ON TO COLLEGE AT LAGUARDIA. INCUMBENT WORKER TRAINING WILL FOCUS ON TECHNOLOGY SKILLS, EMERGENCY PREPAREDNESS, AND VACCINE HESITANCY, AS WELL AS OTHER SPECIALTY TOPICS DEVELOPED BASED ON EMPLOYER FEEDBACK. HRSA ORGANIZATIONAL PRIORITIES IN TELEHEALTH AND BEHAVIORAL HEALTH WILL FEATURE PROMINENTLY IN THE CURRICULUM AND FIELD EXPERIENCES. STUDENTS WILL RECEIVE STIPENDS TO ALLOW THEM TO DEDICATE TIME TO TRAINING AND INTERNSHIPS AS WELL AS EDUCATIONAL CASE MANAGEMENT TO CONNECT TO OTHER RESOURCES ON CAMPUS AND BEYOND. OVER 90% OF STUDENTS ARE EXPECTED TO COMPLETE TRAINING, WITH 100% OF TRAINING COMPLETERS IN THE JOB-SEEKER COHORTS COMPLETING INTERNSHIPS OR APPRENTICESHIPS AT ONE OF SEVERAL DOZEN INTERNSHIP AND APPRENTICESHIP PARTNER ORGANIZATIONS. IN THESE FIELD EXPERIENCES, STUDENTS WILL WORK ON INTER-PROFESSIONAL TEAMS ENGAGING UNDER-SERVED COMMUNITIES. FOLLOWING THEIR FIELD EXPERIENCES, OVER 75% OF GRADUATES ARE EXPECTED TO SECURE EMPLOYMENT IN A CHW-RELATED JOB OR BEGIN A PUBLIC-HEALTH RELA

EXAMINING MODIFIABLE PSYCHOSOCIAL PREDICTORS OF HIV SEROCONVERSION IN A LARGE NATIONWIDE COHORT OF HIGH RISK MEN

BUILDING SECONDARY ENGLISH LEARNER EDUCATOR AND ADMINISTRATOR LEADERSHIP (B-SEAL)

CIPASS-EXL: CITY COLLEGE INITIATIVE TO PROMOTE THE ACADEMIC SUCCESS OF STUDENTS - EXPERIENTIAL LEARNING AND INDUSTRY ENGAGEMENT FOR WORKFORCE READINESS

NUCLEAR CHEMISTRY SUMMER SCHOOL (NCSS)

LIFE-LONG SUCCESS: SUPPORTING ACADEMIC MOMENTUM AND POST-GRADUATE PREPARATION OF HISPANIC STUDENTS

ASSOCIATION OF THE FRAGILE X PREMUTATION WITH COGNITIVE AND BEHAVIORAL SKILLS IN CHILDREN - PROJECT SUMMARY THE OVERARCHING GOAL OF OUR PROPOSAL IS TO ANSWER THE CLINICALLY SIGNIFICANT QUESTION: DOES A FRAGILE X PREMUTATION (PM; AN ALLELE OF 55-200 CGG REPEATS IN THE X-LINKED FMR1 GENE) POSE A SIGNIFICANT RISK TO CHILDHOOD DEVELOPMENT? WHY IS THIS IMPORTANT? AT LEAST ONE IN 300 WOMEN IN THE US CARRIES A PM ALLELE. BECAUSE MOST OF THESE ALLELES ARE SMALL AND NOT PRONE TO LARGE EXPANSIONS, NEARLY HALF OF CHILDREN BORN TO THESE WOMEN WILL INHERIT A PM, WHEREAS FEWER THAN 6% WILL INHERIT A FULL MUTATION (>200 REPEATS), THE ALLELE THAT CAUSES FRAGILE X SYNDROME. PM ALLELES ARE KNOWN TO INCREASE THE RISK FOR TWO LATE-ONSET DISORDERS: FRAGILE X ASSOCIATED TREMOR/ATAXIA SYNDROME (FXTAS) AND FRAGILE X-ASSOCIATED PRIMARY OVARIAN INSUFFICIENCY (FXPOI). ADULTS WITH A PM ALLELE WHO DO NOT HAVE FXTAS OR FXPOI ARE STILL REPORTED TO HAVE EXECUTIVE SKILL AND WORKING MEMORY DEFICITS, VISUOSPATIAL WEAKNESS AND POOR MATH SKILLS, ANXIETY, AND DEPRESSION. FOR CHILDREN WHO CARRY A PM, THERE IS A SIGNIFICANT GAP IN OUR KNOWLEDGE. SOME REPORTS FIND HIGHER RATES OF DEVELOPMENTAL DELAY, ATTENTION DEFICITS, AUTISM, AND ANXIETY AMONG CHILDREN WITH A PM VERSUS NON-CARRIERS, BUT THESE REPORTS ARE LIMITED BY ASCERTAINMENT BIAS AND SMALL SAMPLE SIZE. WE HYPOTHESIZE THAT THE TOXIC EFFECT OF A PM CAN MANIFEST EARLY IN LIFE, LEADING TO ADVERSE NEURODEVELOPMENTAL OUTCOMES AND WE PROPOSE TO TEST THIS RIGOROUSLY AND THOROUGHLY. TO ADDRESS THIS GAP IN KNOWLEDGE, WE HAVE AN OUTSTANDING OPPORTUNITY TO STUDY A LARGE COHORT OF CHILDREN, NOW AGE 3 -12 YEARS, WHO WERE IDENTIFIED PROSPECTIVELY: SPECIFICALLY, 582 CHILDREN WITH A PM AND 958 NON-CARRIERS, ALL IDENTIFIED WHEN THEIR CARRIER MOTHERS UNDERWENT PRENATAL DIAGNOSIS FOR A FRAGILE X MUTATION. THIS UNIQUE COHORT OF CHILDREN HAS MINIMAL POTENTIAL FOR ASCERTAINMENT BIAS. IN AIM 1, PARENTS WILL COMPLETE ONLINE QUESTIONNAIRES TO DESCRIBE THEIR CHILD’S GENERAL HEALTH AND HISTORY OF DIAGNOSED NEURODEVELOPMENTAL PROBLEMS AND TO DETAIL—USING STANDARDIZED QUESTIONNAIRES—THE CHILD’S BEHAVIOR, EXECUTIVE SKILLS, AND SOCIAL RELATEDNESS. IN AIM 2, A SUBSET OF SCHOOL-AGED PARTICIPANTS WHO LIVE IN THE MID-ATLANTIC REGION WILL BE ASSESSED INDIVIDUALLY PRIMARILY VIA REMOTE-ADMINISTERED SEMI-STRUCTURED INTERVIEW AND NEUROPSYCHOLOGICAL MEASURES EXAMINING COGNITIVE, ACADEMIC, SOCIAL AND PSYCHOLOGICAL FUNCTION. MOTHERS WILL ALSO COMPLETE QUESTIONNAIRES REGARDING THEIR OWN PSYCHOLOGICAL WELL-BEING AND PARENTING STRESS. WE WILL EVALUATE ALL PHENOTYPES WITH RESPECT TO SEX, CGG REPEAT LENGTH, AND REPEAT STRUCTURE TO GAIN INSIGHT INTO THE MECHANISMS AND ASSOCIATED RISKS (AIM 3). OUR PRIMARY HYPOTHESIS IS THAT CHILDREN WITH A PM HAVE A HIGHER FREQUENCIES OF NEURODEVELOPMENTAL DEFICITS THAN NON-CARRIER CHILDREN, STRATIFIED BY SEX. THE COMBINATION OF PARENTAL REPORT AND DIRECT ASSESSMENT WILL PROVIDE A COMPREHENSIVE EVALUATION OF COGNITIVE AND BEHAVIORAL SKILLS. THIS WILL RESULT IN A POWERFUL COMBINATION OF DETAILED PHENOTYPIC AND GENETIC INFORMATION THAT WILL UNAMBIGUOUSLY DEFINE THE RISK OF ADVERSE CHILDHOOD DEVELOPMENT POSED BY A PM ALLELE.

UPWARD BOUND IS DESIGNED TO GENERATE IN PROGRAM PARTICIPANTS THE SKILLS AND MOTIVATION NECESSARY TO COMPLETE A PROGRAM OF POSTSECONDARY EDUCATION AND TO ENTER AND SUCCEED IN A POSTSECONDARY EDUCATION.

PREDOMINANTLY BLACK INSTITUTIONS (GRADUATE)

EPIGENETIC SUSCEPTIBILITY OF BEHAVIORAL AND ADDICTIVE DISORDERS DURING PRE/PUBESCENCE AFTER NATURAL DISASTER EXPOSURES IN-UTERO - SUMMARY/ABSTRACT: THE RISK FOR DEVELOPING FUTURE PSYCHIATRIC AND ADDICTION DISORDERS STARTS EARLY IN LIFE, WITH EVIDENCE EMPHASIZING THE CRITICAL CONTRIBUTION OF THE IN UTERO ENVIRONMENT. MATERNAL PSYCHOSOCIAL STRESS HAS A SIGNIFICANT IMPACT ON THE PRENATAL ENVIRONMENT AND CONTRIBUTES TO NEGATIVE HEALTH AND NEUROBEHAVIORAL OUTCOMES IN OFFSPRING. OUR RESEARCH (STRESS IN PREGNANCY, SIP STUDY), ALONG WITH THAT OF OTHERS, HAS SHOWN THAT IN UTERO EXPOSURE TO MATERNAL PSYCHOSOCIAL STRESS IS A MAJOR PREDICTOR OF THE RISK FOR FEAR-RELATED AND IMPULSE CONTROL-RELATED PROBLEMS DURING EARLY CHILDHOOD. WE ARE NOW WELL POSITIONED TO CONDUCT A LONG-TERM FOLLOW-UP OF OUR UNIQUE RACIALLY AND FINANCIALLY DIVERSE SIP STUDY POPULATION TO IDENTIFY BIOMARKERS OF CHILDREN’S BEHAVIOR AND PHYSIOLOGICAL REACTIVITY RELEVANT FOR FUTURE SUBSEQUENT BEHAVIORAL DISORDERS AND ADDICTIVE RISK. DESPITE ITS IMPORTANCE, FEW STUDIES HAVE INVESTIGATED PLACENTAL MOLECULAR SIGNATURES TO BIO-BEHAVIORAL ASSESSMENTS FROM EARLY LIFE THROUGH THE PRE/PUBERTAL PHASE. EXPLOITING THE SIP STUDY'S BIO-REPOSITORIES AND DEEP-PHENOTYPED CHILD BEHAVIORS, OUR PRELIMINARY RESULTS SHOW THAT EPIGENETIC CHANGES OF THE HYPOTHALAMIC-PITUITARY-ADRENAL (HPA) AXIS AND IMMUNE SYSTEMS ARE ASSOCIATED WITH FEAR, ANXIETY, AND EMOTION DYSREGULATION AMONG CHILDREN EXPOSED TO IN UTERO MATERNAL STRESS. THE SIP STUDY COHORT HAS MANY STRENGTHS: ITS CONSISTENT LONG-TERM FOLLOW-UP, FROM IN UTERO, ITS DIVERSITY (FINANCIALLY AND RACIALLY), ITS EXTENSIVE REPOSITORY OF STORED BIOSPECIMENS (PLACENTA, TOENAIL, HAIR SAMPLES), AND ITS QUASI-EXPERIMENTAL DESIGN. THE COHORT IS NOW ENTERING PRE/PUBERTY (AGES 9-13), A TIME FOR RAPID SOCIAL AND BIOLOGICAL TRANSITION AND A PEAK TIME FOR THE EMERGENCE OF MALADAPTIVE, RISK-TAKING BEHAVIORS WITH THE BRAIN STILL DEVELOPING COGNITIVE FUNCTIONS. USING THIS UNPARALLELED OPPORTUNITY, WE WILL FOLLOW THE COHORT TO 1) EXAMINE THE ROLE OF EXPOSURE TO SS IN UTERO ALONG WITH THE EFFECT OF POSTNATAL STRESS (NORMATIVE STRESS, PARENTING) ON NEURODEVELOPMENTAL FUNCTIONING, AS MEASURED BY MULTIPLE BEHAVIORAL, PHYSIOLOGICAL, AND NEUROPSYCHOLOGICAL ASSESSMENTS; 2) DETERMINE THE RELATIONSHIP BETWEEN THE PRENATAL EPIGENOME SIGNATURE IN THE PLACENTA (ALONG WITH AN A PRIORI FOCUS ON THE HPA-AXIS AND IMMUNE NETWORK GENES) ON THE SUBSEQUENT RISK FOR NEGATIVE BEHAVIORAL CHARACTERISTICS (I.E., EXCESSIVE ANXIETY AND DISRUPTIVE BEHAVIORS) AND IMPAIRED EXECUTIVE FUNCTIONING, KNOWN TO ELEVATE THE RISK FOR EARLY INITIATION OF SUBSTANCE USE. FOLLOWING OUR PRIOR WORK, WE WILL ALSO EXAMINE SEX-SPECIFIC MANIFESTATIONS OF THE BEHAVIORAL PHENOTYPES (MORE INTERNALIZING PROBLEMS IN GIRLS AND EXTERNALIZING IN BOYS). WE WILL FURTHER EXPLORE THE MODERATING ROLE OF SOCIOECONOMIC STATUS WHEN INTERSECTING WITH PRENATAL SS-STRESS AND POSTNATAL STRESS ON INDIVIDUAL DIFFERENCES IN COGNITIVE NEURO-BEHAVIORS, WHICH MAKE PRE/PUBESCENT CHILDREN MORE VULNERABLE FOR A SUBSEQUENT ONSET OF BEHAVIORAL AND ADDICTIVE DISORDERS. WE WILL BUILD ON OUR UNIQUE REPOSITORY OF STORED BIOSPECIMENS AND PROFILE CHROMATIN ACCESSIBILITY ACROSS THE EPIGENOME AND RNA EXPRESSION NETWORK IN THE PLACENTA. GIVEN THE STEEPLY INCREASING INCIDENCE OF ADVERSE STRESSORS, ESPECIALLY NATURAL DISASTERS (E.G., HURRICANES, WILDFIRES AND PANDEMICS), INVESTIGATION OF THE SHORT- AND LONG-TERM IMPACT OF SS-STRESS ON NEURODEVELOPMENT FROM IN UTERO THROUGH PRE/PUBERTY, WILL HELP US TO IDENTIFY PROBLEMS AND POTENTIALLY LEAD TO SIGNIFICANT INTERVENTIONS FOR MOTHER AND CHILD.

IMPROVING PREVENTION SYSTEMS TO REDUCE DISPARITIES FOR HIGH PRIORITY POPULATIONS.

NEW; HIGH-ENERGY QCD IN HEAVY-ION COLLISIONS; PI - JAMAL JALILIAN-MARIAN

MAPPING AND EXPLOITING THE INTERNAL WIRING OF DYNAMIC PROTEIN STRUCTURES

INTERVENTION TARGETING SUBSTANCE USING OLDER ADULTS WITH HIV

PURPOSE: THE FUNDING WILL BE USED TO UPGRADE OUTDATED LAB EQUIPMENT IN TEACHING LABS THAT SERVE SIX ACADEMIC DEPARTMENTS: BIOLOGY, CHEMISTRY, COMPUTER SCIENCE, ENGINEERING AND ENVIRONMENTAL SCIENCE, MATHEMATICS, AND PHYSICS AND ASTRONOMY. THESE INVESTMENTS WILL MAKE IT POSSIBLE FOR CUNY COLLEGE OF STATEN ISLAND INSTRUCTORS TO CREATE IMMERSIVE LEARNING OPPORTUNITIES FOR GENERAL-EDUCATION COURSES AS WELL AS MAJOR COURSES IN STEM SUBJECTS. ACTIVITIES TO BE PERFORMED: THIS PROJECT WILL PROCURE EQUIPMENT, SOFTWARE, AND SUPPLIES, TO SIGNIFICANTLY IMPROVE THE INFRASTRUCTURE IN SEVEN DEPARTMENTAL TEACHING LABS. SIX DEPARTMENTS ARE HOUSED IN THE DIVISION OF SCIENCE AND TECHNOLOGY AND ONE DEPARTMENT IS PART OF THE SCHOOL OF HEALTH SCIENCES. THE PROJECT IS PLANNED TO BE COMPLETED IN 12 MONTHS. THE LEAD PI AND HIS PROJECT TEAM WILL WORK CLOSELY WITH BENEFITING DIVISIONS AND DEPARTMENTS TO ENSURE THAT PURCHASING AND PLACEMENT OF EQUIPMENT IS DONE WITHOUT CAUSING DISRUPTION TO THE ON-GOING TEACHING PROGRAMS THAT OCCUR IN THESE SPACES. ADDITIONALLY, AN EXTERNAL EVALUATOR WILL CONDUCT PRE-AND POST-ASSESSMENTS THAT ARE BOTH FORMATIVE AND SUMMATIVE TO ASSIST THE COLLEGE IN MEETING ITS STUDENT SUCCESS AND RETENTION METRICS.EXPECTED OUTCOMES: OVERALL, THE GOAL OF THESE STRATEGIC INVESTMENTS IS TO PREPARE STUDENTS TO BE CAREER READY GRADUATES BY TRAINING STUDENTS USING EQUIPMENT THAT ADHERES TO CURRENT INDUSTRY STANDARDS AND INTRODUCES THEM TO EMERGING IDEAS AND DEVELOPMENTS IN THESE FIELDS OF STUDY. INTENDED BENEFICIARIES: THE UNDERGRADUATE STUDENTS WILL BE THE PRIMARY BENEFICIARIES OF THIS PROJECT'S INVESTED EQUIPMENT. THE UNDERGRADUATES WILL PARTICIPATE IN A VARIETY OF ACTIVITIES TO ENCOURAGE HANDS-ON LEARNING, BOTH GENERAL EDUCATION COURSES AND MAJOR COURSES. SUBRECIPIENT ACTIVITIES: THE RECIPIENT DOES NOT INTEND TO SUBAWARD FUNDS.

PROJECTS FOR CHILDREN & YOUNG ADULTS WHO ARE DEAF-BLIND

STRENGTHENING INSTITUTIONS - HISPANIC SERVING INSTITUTIONS

STRENGTHENING INSTITUTIONS - HISPANIC SERVING INSTITUTIONS

INTRODUCE INFANT/TODDLER CARE AND EXTEND EVENING HOURS FOR STUDENT PARENTS.

COMMUNITY BASED JOB TRAINING

VIRTUAL POPULATION OBESITY PREVENTION (VPOP) LABS: COMPUTATIONAL, MULTI-SCALE MODELS FOR OBESITY SOLUTIONS

THE EVOLUTIONARY BASIS OF THE DEVELOPMENTAL COURSE AND ETIOLOGIES OF ANXIETY AND DISRUPTIVE BEHAVIORS DURING EARLY ADOLESCENCE - SUMMARY/ABSTRACT: ACCUMULATING EVIDENCE, INCLUDING OUR OWN, INDICATES THAT IN UTERO EXPOSURE TO PSYCHOSOCIAL STRESS IS ASSOCIATED WITH RISKS FOR ELEVATED ANXIETY (ANX) AND DISRUPTIVE BEHAVIOR (DB) SYMPTOMATOLOGY. IN THIS APPLICATION, WE WILL BUILD ON OUR EXISTING BIRTH COHORT OF CHILDREN EXPOSED AND UNEXPOSED TO SUPERSTORM SANDY (SS) IN UTERO. SS RANDOMLY “ASSIGNED” STRESSFUL CONDITIONS TO PREGNANT WOMEN AND THEIR OFFSPRING IN OUR COHORT, GIVING US A UNIQUE OPPORTUNITY TO CONDUCT A QUASI-EXPERIMENT OF IN UTERO STRESS. USING OUR DEEPLY PHENOTYPED COHORT, WE PROPOSE TO INVESTIGATE WHETHER IN UTERO SS EXPOSURE MODULATES THE IMPACT OF THE POSTNATAL STRESSFUL ENVIRONMENT, EITHER AMPLIFYING (DOUBLE-HIT ACCELERATION MODEL) OR SHIELDING (STRESS INOCULATION MODEL) THE EFFECTS OF POSTNATAL STRESS ON ANX AND DB SYMPTOMATOLOGY. WE WILL CONTINUE TO MEASURE DIFFERENT TYPES OF POSTNATAL STRESS (NORMATIVE, POOR PARENTING, AND COVID-RELATED) TO EXAMINE IF MAGNITUDE, NATURE, TIMING AND DURATION OF THE POSTNATAL STRESSORS INFLUENCES THE DIRECTION AND IMPACT ON SUCH SYMPTOMATOLOGY. AS WELL AS THE DSM-BASED DIAGNOSTIC OUTCOMES, WE WILL UTILIZE THE NIMH RDOC AND FOCUS ON NEGATIVE VALENCE AND COGNITIVE CONTROL SYSTEMS (NVS/CCS), WHICH WILL ENABLE A TRANSDIAGNOSTIC PERSPECTIVE OF PRE- AND POSTNATAL STRESS-RELATED CHANGES IN BEHAVIOR AND THE BRAIN. FOLLOWING OUR PRIOR WORK, WE WILL ALSO EXAMINE SEX-SPECIFIC MANIFESTATIONS OF THE BEHAVIORAL PHENOTYPES (MORE INTERNALIZING PROBLEMS IN GIRLS AND MORE EXTERNALIZING IN BOYS) AND EXPLORE THE MODERATING ROLE OF SES WHEN INTERSECTING WITH INDIVIDUAL DIFFERENCES IN BEHAVIORS. AS THE BRAIN IS THE CENTRAL MODULATORY ORGAN OF STRESS/ADAPTATION AND REGULATION, WE WILL USE NEUROIMAGING TO ASSESS CHANGES IN BRAIN STRUCTURE, FUNCTION, AND CONNECTIVITY IN LIMBIC-FRONTAL CIRCUITRY DURING EARLY PRE- AND POST-PUBERTY, USING A SUBSAMPLE OF OUR COHORT. OUR COHORT WAS FOLLOWED FROM IN UTERO, WITH COMPLETED FOLLOW-UP ASSESSMENTS (NEUROBEHAVIORAL, CLINICAL, AND BIOLOGICAL SPECIMENS), WHICH WILL CONTINUE AS THEY ENTER PRE/PUBERTY (AGES 9-13), A TIME OF PEAK RISKS FOR SUCH PROBLEMS AND SEX-DIMORPHISM. SPECIFICALLY, WE WILL: 1) EXAMINE THE EFFECTS OF SS-RELATED STRESS AND THE POSTNATAL PSYCHOSOCIAL ENVIRONMENT ON TRAJECTORIES OF CLINICAL AND ADAPTIVE NEUROBEHAVIORS; 2) STUDY THE IMPACT OF PRENATAL SS STRESS AND POSTNATAL STRESS ON NVS/CCS BRAIN OUTCOMES (STRUCTURE AND FUNCTION) AND EVALUATE THE EXTENT TO WHICH NVS/CCS STRUCTURAL CHANGES MEDIATE BETWEEN PRENATAL SS-EXPOSURE AND CHILD ANXIETY AND DB SYMPTOMS; AND 3) DEVELOP PREDICTIVE MODELS FOR NVS/CCS OUTCOMES IN EARLY ADOLESCENCE BASED ON BIOLOGICAL AND BEHAVIORAL MEASURES OBTAINED IN UTERO AND/OR THE FIRST DECADE OF THE CHILD’S LIFE. AS PRE/PUBERTY IS AN IMPORTANT PERIOD OF DEVELOPMENTAL TRANSITION AND HEIGHTENED RISK FOR ANX AND DB, WE WILL BUILD ON OUR UNIQUE REPOSITORY OF BOTH CLINICAL AND STORED HAIR SAMPLES AND CONTINUE TO CHART CHILDREN’S NEUROBEHAVIORAL DEVELOPMENT AND RISK FOR PSYCHOPATHOLOGY THROUGH AGES 9-13. TOGETHER WITH THE INCLUSION OF NEUROIMAGING TO INVESTIGATE NEURAL MECHANISMS CENTERED ON THE NVS/CCS AND USING TASKS FROM THE ABCD STUDY, OUR STUDY IS UNIQUELY POSITIONED TO ELUCIDATE THE MECHANISMS OF FETAL PROGRAMING AND THREAT SENSITIVITY IN THE NVS/SSV THAT MODULATE THE RISKS FOR ANXIETY AND REACTIVE AGGRESSION.

ACCESSIBLE CARE INTERVENTION FOR ENGAGING PEOPLE WHO INJECT ILLICIT DRUGS (PWID) IN HEPATITIS C CARE

STUDENT SUPPORT SERVICES PROGRAM

TRADE ADJUSTMENT ASSISTANCE COMMUNITY COLLEGE AND CAREER TRAINING

PROMISE - PROGRAM REFINEMENTS TO OPTIMIZE MODEL IMPACT AND SCALABILITY BASED ON EVIDENCE

COMPULSIVE BEHAVIORS MENTAL HEALTH AND HIV RISK

STRENGTHENING INSTITUTIONS - HISPANIC SERVING INSTITUTIONS

UPWARD BOUND IS DESIGNED TO GENERATE IN PROGRAM PARTICIPANTS THE SKILLS AND MOTIVATION NECESSARY TO COMPLETE A PROGRAM OF POSTSECONDARY EDUCATION AND TO ENTER AND SUCCEED IN A POSTSECONDARY EDUCATION.

TYPE 2 - LOI02170327 - A REGIONAL EARTH SYSTEM MODEL OF THE NORTHEAST CORRIDOR: ANALYZING 21ST CENTURY CLIMATE AND ENVIRONMENT

NEW YORK DEAF-BLIND COLLABORATIVE

BIOLOGICAL STUDIES OF ALPHA-HYDROXYTROPOLONES

BALANCING THE SCALES SERIES II