Calm Inc

CARES ACT STIMULUS FUNDS FOR INSITUTION.

THIS SUPPORTS COMMUNITY COLLEGE STUDENTS IMPACTED BY COVID-19.

WASTE DISPOSAL GRANTS - 09/10 STIMULUS

TEACHING AMERICAN HISTORY GRANTS

QUANTITATIVE HIGH THROUGHPUT SCREENING FOR SMALL MOLECULES TARGETING CD47 IN CANCER

DRUG-FREE COMMUNITIES (DFC) SUPPORT PROGRAM- NEW

QUANTITATIVE HIGH THROUGHPUT SCREENING FOR SMALL MOLECULES TARGETING CD47 IN CANCER - SCIENTIFIC ABSTRACT CD47 IS AN IMMUNE CHECKPOINT MOLECULE THAT DOWNREGULATES KEY ASPECTS OF BOTH THE INNATE AND ADAPTIVE ANTI- TUMOR IMMUNE RESPONSE VIA THE INHIBITORY RECEPTOR SIRPA ON TUMOR ASSOCIATED MYELOID CELLS INCLUDING MACROPHAGE AND MYELOID-DERIVED SUPPRESSOR CELLS. CD47 IS EXPRESSED AT HIGHER LEVELS IN SOLID AND HEMATOLOGICAL TUMORS THAN NONMALIGNANT TISSUES AND CORRELATES WITH TREATMENT RESISTANCE AND POOR PROGNOSIS. THIS HAS LED TO THE DEVELOPMENT OF BIOLOGICS SUCH AS HUMANIZED CD47 ANTIBODIES THAT BLOCK SIRPA ENGAGEMENT WHICH ARE BEING TESTED IN CLINICAL TRIALS. UNFORTUNATELY, TOXICOLOGICAL ISSUES, INCLUDING ANEMIA RELATED TO UBIQUITOUS CD47 EXPRESSION AND POOR TUMOR MICROENVIRONMENT (TME) SELECTIVITY VS NORMAL CELLS, ARE BARRIERS TO THEIR CLINICAL ADVANCEMENT. ADDITIONAL SIRPA-CD47 BLOCKING MODALITIES ARE NEEDED TO REALIZE THE FULL POTENTIAL OF THIS CRITICAL IMMUNOTHERAPY TARGET. WE HYPOTHESIZE THAT USING SMALL MOLECULES TARGETING SIRPA TO BLOCK SIRPA-CD47 INTERACTION WILL RESULT IN BETTER TME SELECTIVITY, LOWER TOXICITY, ENHANCED SOLID TUMOR PENETRATION, AND LEAD TO GREATER ANTI-TUMOR EFFICACY. TO ADDRESS THIS HYPOTHESIS, WE BUILT AN INNOVATIVE MULTIDISCIPLINARY PROGRAM TO DEVELOP THE FIRST SIRPA-TARGETING SMALL MOLECULES AND MADE SUBSTANTIAL PROGRESS TOWARD THIS GOAL WITH OUR CURRENT NIH AWARD. LIKE MANY IMMUNE CHECKPOINTS, SIRPA-CD47 IS A PROTEIN-PROTEIN INTERACTION COMPLEX AND IS CHALLENGING TO TARGET USING SMALL MOLECULES AS WE DESCRIBED. HOWEVER, USING A COMBINATION OF X-RAY CRYSTALLOGRAPHY FRAGMENT SCREENING, PROTEIN-OBSERVED HETERONUCLEAR SINGLE QUANTUM COHERENCE (HSQC) NMR, AND HOMOGENEOUS TIME RESOLVED FLUORESCENCE (HTRF), WE IDENTIFIED CHEMOTYPES THAT BOUND SIRPA. THESE MOLECULES DRAMATICALLY ALTERED THE CONFORMATION OF SIRPA REGIONS AT THE CD47 INTERFACE, PROVIDING A MECHANISM FOR DISRUPTION OF THE COMPLEX. WE SUBSEQUENTLY IMPROVED THESE INITIAL X-RAY SCREENING HITS INTO HIGHLY LIGAND-EFFICIENT (LE = 0.45) PROBES THAT BOUND SIRPA AND INHIBITED CD47 INTERACTION. THESE NOVEL SIRPA-BINDING MOLECULES HAVE BEEN VALIDATED BY HTRF, ALPHASCREEN, ISOTHERMAL CALORIMETRY, HSQC NMR, AND X-RAY CRYSTALLOGRAPHY, YIELDING A CONSISTENT SAR PROFILE AND PROVIDE A SPRINGBOARD TO A HIGH IMPACT HIT TO LEAD CAMPAIGN. USING OUR UNIQUE MOLECULAR DESIGN TOOLS, WE DEVELOPED A STRUCTURE-BASED STRATEGY TO FURTHER OPTIMIZE OUR HITS INTO POTENT AND SELECTIVE LEAD-LIKE MOLECULES. TO SUPPORT THIS CAMPAIGN, WE ESTABLISHED AN INNOVATIVE SET OF BIOLOGICAL IN VITRO CHARACTERIZATION ASSAYS TO TEST THEIR ANTI-TUMOR IMMUNE ACTIVITY AND MECHANISM OF ACTION. THE OVERALL OBJECTIVE OF THIS MERIT AWARD EXTENSION APPLICATION IS TO CONTINUE THE DEVELOPMENT OF OUR VALIDATED SIRPA-TARGETING HITS INTO POTENT BIOLOGICALLY ACTIVE LEAD MOLECULES READY FOR IN VIVO EVALUATION ACCORDING TO THE FOLLOWING SPECIFIC AIMS: AIM 4. DESIGN, SYNTHESIS, AND BIOCHEMICAL EVALUATION OF POTENT AND SELECTIVE CD47-SIRPA INHIBITING SMALL MOLECULES FROM VALIDATED SIRPA-BOUND FRAGMENT HITS. THE GOAL OF THIS AIM IS TO GENERATE MULTIPLE CANDIDATE MOLECULES BY LOCAL OPTIMIZATION OF THE HIT CORE AND GROWING INTO ADJACENT SUBPOCKETS WITH SUFFICIENT POTENCY TO ESTABLISH THEIR BIOLOGICAL ACTIVITY IN AIM 5. AIM 5. EVALUATION AND OPTIMIZATION OF CD47-SIRPA INHIBITING SMALL MOLECULE ACTIVITIES IN CLINICALLY-RELEVANT MODELS. TO DETERMINE THE POTENCY NECESSARY FOR SMALL MOLECULE SIRPA-CD47 INHIBITORS TO ELICIT BIOLOGICAL ACTIVITY, WE WILL EVALUATE THEIR IN VITRO ACTIVITY AND TARGET SELECTIVITY USING A SERIES OF VALIDATED BIOLOGICAL MECHANISM OF ACTION ASSAYS AND TUMOR-IMMUNE INTERACTION CHARACTERIZATION SYSTEMS. THE SUCCESSFUL COMPLETION OF THESE AIMS WILL RESULT IN LEAD CANDIDATE MOLECULES FOR SUBSEQUENT EVALUATION OF ANTI-TUMOR IMMUNE ACTIVITY EVALUATION USING WELL-CHARACTERIZED INDICATION-SPECIFIC ANIMAL MODELS. OUR NOVEL APPROACH TO THIS COMPELLING TARGET WILL CREATE FIRST OF THEIR KIND CHEMI

THIS IS A BROWNFIELDS COOPERATIVE AGREEMENT TO MONTCALM COUNTY, MICHIGAN TO EVALUATE PROPERTIES WHICH ARE BELIEVED TO BE CONTAMINATED WITH HAZARDOUS

LEVERAGING AN ACADEMIC-INDUSTRY PARTNERSHIP TO DEVELOP A CANCER-SPECIFIC MOBILE MEDITATION APP - 1 PROJECT SUMMARY/ABSTRACT 2 APPROXIMATELY 15.5 MILLION US CANCER PATIENTS/SURVIVORS EXPERIENCE A HOST OF RESIDUAL SYMPTOMS (E.G., 3 FATIGUE, ANXIETY, DEPRESSION, PAIN, SLEEP DISTURBANCE) AND REDUCED QUALITY OF LIFE THAT ARE OFTEN NOT RESOLVED WITH 4 EVEN THE BEST-AVAILABLE CURRENT STANDARD OF CARE THERAPIES. RESIDUAL SYMPTOM BURDEN IMPAIRS CANCER SURVIVOR 5 FUNCTIONING AND LEADS TO INCREASED RATES OF DISABILITY AND HEALTHCARE UTILIZATION, COSTING $125 BILLION EVERY YEAR. 6 CANCER PATIENTS/SURVIVORS WANT AND NEED COMPLEMENTARY STRATEGIES TO ACCOMPANY STANDARD THERAPIES. 7 RESEARCH HAS DEMONSTRATED THE BENEFITS OF MINDFULNESS-BASED THERAPIES, SUCH AS MEDITATION, FOR 8 ALLEVIATING CANCER-RELATED SYMPTOMS (E.G., FATIGUE, ANXIETY, DEPRESSION, AND SLEEP DISTURBANCE).MEDITATION-BASED 9 PROGRAMS ARE TYPICALLY CONDUCTED IN-PERSON, IN CLINIC SETTINGS; HOWEVER, THESE PROGRAMS ARE EXPENSIVE AND 10 DIFFICULT TO SUSTAIN, AND CANCER PATIENTS REPORT BARRIERS TO PARTICIPATING (E.G., TRAVEL DEMANDS, FATIGUE, PAIN, AND 11 SCHEDULING DIFFICULTIES). SMARTPHONE-BASED MEDITATION IS A FEASIBLE AND NOVEL METHOD FOR DELIVERING MEDITATION 12 TO CANCER PATIENTS/SURVIVORS. MOBILE APPS AND ONLINE MEDITATION PROGRAMS HAVE DEMONSTRATED SHORT-TERM BENEFITS 13 FOR CANCER PATIENTS/SURVIVORS; HOWEVER, THE CURRENTLY AVAILABLE COMMERCIAL MEDITATION APPS ARE LIMITED IN THEIR 14 ENGAGEMENT, ACCEPTABILITY, AND APPLICABILITY TO CANCER PATIENTS/SURVIVORS’ UNIQUE EXPERIENCES AND HAVE NOT BEEN 15 EVALUATED FOR FEASIBILITY OR EFFICACY. THERE IS AN UNMET NEED FOR A COMMERCIALLY-AVAILABLE, EVIDENCE-BASED 16 MEDITATION APP SPECIFICALLY DESIGNED FOR CANCER PATIENTS/SURVIVORS. INCORPORATING STAKEHOLDER FEEDBACK (I.E., 17 PATIENTS AND HEALTHCARE PROVIDERS) IN THE EARLY DESIGN PHASE WILL FACILITATE THE DEVELOPMENT OF A MEDITATION APP 18 TRULY TARGETED FOR THE END USERS THAT CAN BE MADE COMMERCIALLY AVAILABLE, THEREBY IMPROVING UPTAKE AND IMPACT 19 IN PATIENT POPULATIONS. CALM, A POPULAR CONSUMER-BASED MEDITATION APP WITH 70 MILLION DOWNLOADS AND 2 MILLION 20 SUBSCRIBERS, PROVIDES A PLATFORM FROM WHICH TO DEVELOP AN ACCESSIBLE STANDALONE CANCER-SPECIFIC MEDITATION APP. 21 THIS PROJECT WILL: 1) GATHER FEEDBACK ABOUT THE CURRENT CALM APP FROM AN ADVISORY COMMITTEE (N=20) CONSISTING 22 OF CANCER PATIENTS/SURVIVORS (N=10, 5 OF EACH) AND HEALTHCARE PROVIDERS (N=10), 2) DESIGN A CANCER-SPECIFIC 23 MEDITATION APP PROTOTYPE, AND 3) BETA-TEST THE PROTOTYPE IN CANCER PATIENTS/SURVIVORS (N=30). 24 A STANDALONE MEDITATION APP DESIGNED FOR AND TESTED BY CANCER PATIENTS/SURVIVORS, LEVERAGING A POPULAR 25 AND VALIDATED MEDITATION APP PLATFORM, TO BE MADE COMMERCIALLY AVAILABLE, IS INNOVATIVE AND COULD PROVIDE A 26 SCALABLE, HIGHLY ENGAGING SYMPTOM-MANAGEMENT TOOL THAT ADDRESSES CANCER PATIENTS/SURVIVORS’ UNIQUE NEEDS. 27 IF OUR KEY FEASIBILITY MILESTONES ARE MET, WE WILL FURTHER REFINE THE CANCER-SPECIFIC APP AND CONDUCT A RANDOMIZED 28 CONTROLLED TRIAL TO DETERMINE THE APP’S LONG-TERM EFFICACY IN REDUCING SYMPTOM BURDEN IN CANCER PATIENTS/SURVIVORS 29 (PHASE 2) THAT CAN LATER BE COMMERCIALIZED AND MARKETED TO CANCER PATIENTS/SURVIVORS, HEALTHCARE PROVIDERS, AND 30 CLINICS. (PHASE 3).

THE COALITION WILL PREVENT AND REDUCE YOUTH SUBSTANCE USE BY IMPLEMENTING THE FOLLOWING STRATEGIES: RECRUIT MORE KEY STAKEHOLDERS AS SECTOR REPRESENTATIVES AND BROADEN MEMBER PARTICIPATION AT THE TEAM WORK LEVEL; EXPAND CHANNELS AND METHODS OF COMMUNICATION ACROSS ALL SECTORS; EXPAND COALITION EVALUATION CAPACITY; REDUCE YOUTH ACCESS TO ALCOHOL; REDUCE AVAILABILITY OF PRESCRIPTION DRUGS TO YOUTH; AND PROMOTE THE MAP PROGRAM WITHIN THE MEDICAL COMMUNITY.

DEVELOPMENT OF A UNIVERSAL PRODRUG APPROACH FOR ANTIBODY BASED THERAPEUTICS

SBIR PHASE I: A STAKEHOLDER MANAGEMENT PLATFORM FOR ENVIRONMENTAL JUSTICE -THE BROADER IMPACT/COMMERCIAL IMPACT OF THIS SMALL BUSINESS INNOVATION RESEARCH PHASE I PROJECT IS TO BREAK THE NEGATIVE FEEDBACK LOOP OF MULTI-GENERATION, MULTI-SECTOR CASCADING IMPACTS OF ENVIRONMENTAL AND SOCIAL INJUSTICES BY PROVIDING EFFECTIVE TOOLS FOR ENGAGEMENT OF UNDERSERVED COMMUNITIES. THE TIDE IS TURNING AS ENVIRONMENTAL JUSTICE POLICIES ARE INCREASINGLY BEING ADOPTED BY GOVERNMENTS AT THE FEDERAL, STATE, COUNTY, AND REGIONAL LEVELS - TO EXPLICITLY AND MEANINGFULLY ENGAGE UNDERSERVED COMMUNITIES EARLY AND OFTEN IN ALL REGULATORY AND PLANNING PHASES. THIS PROJECT ADDRESSES THE INITIAL CHALLENGES AROUND AUTOMATING THE PROCESS OF IDENTIFYING, BUILDING TRUST WITH, AND ELEVATING COMMUNITY-BASED ORGANIZATIONS AND UNDERSERVED COMMUNITIES WITH THE GOAL OF ACCELERATING THE IMPLEMENTATION OF EQUITABLE CLIMATE-SMART INFRASTRUCTURE PROJECTS. THE PROPOSED INNOVATION WILL HELP AGENCIES SCALE UP THEIR REACH, ACCURACY, AND EFFICIENCY OF COMMUNITY ENGAGEMENT, ESTABLISH AND BUILD TRUST WITH UNDERSERVED COMMUNITIES, AND ACCELERATE COMMUNITY PARTICIPATION IN PLANNING AND INFRASTRUCTURE PROJECTS THROUGHOUT THE UNITED STATES. THE PROJECT HELPS COMMUNITY LEADERS RAISE THEIR VOICE AND VISIBILITY WITH AGENCIES, GAIN ACCESS TO TIMELY INFORMATION ACROSS DIFFERENT AGENCIES, AND GAIN ACCESS TO FUNDING OPPORTUNITIES. SUCCESSFULLY IMPLEMENTING THIS PROJECT HAS THE POTENTIAL TO REDUCE COST BURDENS ON COMMUNITIES, WHILE ALSO SUPPORTING ECONOMIC EMPOWERMENT IN COMMUNITIES WHERE THE PROJECT IS DEPLOYED. THIS SMALL BUSINESS INNOVATION RESEARCH PHASE I PROJECT WILL DEMONSTRATE FEASIBILITY OF USING TEXTAI (NATURAL LANGUAGE PROCESSING USING ARTIFICIAL INTELLIGENCE (AI)) AND GEOAI (GEOGRAPHIC INFORMATION SYSTEMS USING AI) TO PERFORM LOCATION-BASED STAKEHOLDER DISCOVERY OF COMMUNITY BASED ORGANIZATIONS (CBOS). THIS GOAL POSES TECHNICAL CHALLENGES: HIGH VARIATION IN UNSTRUCTURED DATA; QUALITY OF MANUAL ANNOTATIONS; COMPLEXITY AND DIVERSITY OF ATTRIBUTES; AND DISAMBIGUATION OF LOCATION IDENTIFICATION AND SOCIAL CHALLENGES. THE COMMUNITIES OF INTEREST HAVE LOW TRUST IN THE GOVERNMENT AND TECHNOLOGY AND NEED TRANSPARENT DATA SHARING AND ETHICS. THE KEY INNOVATION IS A WORKFLOW THAT COMBINES DEEP TECHNOLOGY DEVELOPMENT WITH PARTICIPATORY AND INCLUSIVE CO-DESIGN WITH COMMUNITY-BASED ORGANIZATIONS AND GOVERNMENT. IF THE PROJECT SUCCEEDS, IT WILL HAVE SUBSTANTIAL PAYBACK FOR UNDERSERVED COMMUNITIES. THE FIRST USE CASE IS WITH THE SAN FRANCISCO BAY CONSERVATION AND DEVELOPMENT COMMISSION, WHICH HAS THE RIGHT SIZE AND SCOPE OF JURISDICTION TO CAPTURE VARIATIONS IN DATA TYPE, STAKEHOLDERS, AND USERS - AND INCLUDES A HIGHLY DIVERSE SET OF DEMOGRAPHICS ACROSS URBAN AND RURAL COMMUNITIES - WHILE ALSO BEING SMALL ENOUGH TO MANAGE ITS DATA. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

COMM. PREVN. INITIATIVE TO REDUCE YTH. ACCESS TO ALC, TOBACCO, MARIJUANA & PRESCR

EDUCATING ROBOT MAINTENANCE AND REPAIR TECHNICIANS TO ADDRESS WORKFORCE GAPS IN AUTOMATION AND SKILLED TRADES

ASSISTANCE TO FIREFIGHTERS GRANT

PERFORM FUNDING SYS

PUBLIC AND INDIAN HOUSING

PERFORM FUNDING SYS

PURPOSE: THE PUBLIC HOUSING CAPITAL FUND PROGRAM (CFP) WAS CREATED BY AN AMENDMENT TO THE 1937 ACT BY THE QUALITY HOUSING AND WORK RESPONSIBILITY ACT (QHWRA) IN 1998 (ADDING SECTION 9(D) TO THE 1937 ACT MERGING PREVIOUS MODERNIZATION AND DEVELOPMENT PROGRAMS). THE CFP PROVIDES FINANCIAL ASSISTANCE IN THE FORM OF GRANTS TO APPROXIMATELY 2,770 PUBLIC HOUSING AGENCIES (PHAS), SERVING NEARLY ONE MILLION UNITS, IN ALL 50 STATES AND TERRITORIES, TO CARRY OUT CAPITAL AND MANAGEMENT ACTIVITIES INCLUDING THOSE LISTED IN SECTION 9(D)(1) OF THE UNITED STATES HOUSING ACT OF 1937 (1937 ACT). THE MAIN PURPOSE OF THE CFP FORMULA GRANT IS TO FUND PUBLIC HOUSING MODERNIZATION, DEVELOPMENT, MANAGEMENT IMPROVEMENTS, AND THE OTHER ELIGIBLE ACTIVITIES DESCRIBED IN 24 CFR PART 905. ADDITIONAL INFORMATION ON THE PUBLIC HOUSING CAPITAL FUND IS LOCATED ON THE OFFICE OF CAPITAL IMPROVEMENTS WEBSITE: OFFICE OF CAPITAL IMPROVEMENTS | HUD.GOV / U.S. DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT (HUD) ADDITIONAL INFORMATION ON PUBLIC HOUSING FUNDING CAN BE FOUND BY ACCESSING THE WEBSITE BELOW AND REVIEWING THE PUBLIC HOUSING DASHBOARD LINKED UNDER THE “DATA DASHBOARD AND ANALYTICS”. PUBLIC HOUSING | HUD.GOV / U.S. DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT (HUD); ACTIVITIES TO BE PERFORMED: THE PHAS RECEIVE FEDERAL FUNDS FROM THE U.S. DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT (HUD) TO ADMINISTER THE PUBLIC HOUSING FUND. PUBLIC HOUSING CAPITAL FUNDS MAY ONLY BE USED FOR ACTIVITIES THAT ARE DESCRIBED AS ELIGIBLE ACTIVITIES IN 24 CFR 905.200 AND ARE EITHER SPECIFIED IN AN APPROVED 5-YEAR ACTION PLAN OR APPROVED BY HUD FOR EMERGENCY WORK OR WORK NEEDED BECAUSE OF A NON-PRESIDENTIALLY DECLARED NATURAL DISASTER. PUBLIC HOUSING DEVELOPMENT, MODERNIZATION, AND FINANCING ARE THE MAJOR ACTIVITIES TO BE PERFORMED. DEVELOPMENT IS ACTIVITIES AND RELATED COSTS THAT ADD TO (OR SIGNIFICANTLY RECONFIGURE) PUBLIC HOUSING UNITS IN A PHA’S INVENTORY, INCLUDING CONSTRUCTION AND ACQUISITION OF ADDITIONAL PUBLIC HOUSING UNITS, WITH OR WITHOUT REHABILITATION, AND ANY-AND-ALL UNDERTAKINGS NECESSARY FOR PLANNING, DESIGN, FINANCING, LAND ACQUISITION, DEMOLITION, CONSTRUCTION, OR EQUIPMENT OF PUBLIC HOUSING UNITS, AND RELATED BUILDINGS, FACILITIES, AND/OR APPURTENANCES (I.E., NON-DWELLING FACILITIES/SPACES). DEVELOPMENT ALSO INCLUDES ANY MIXED-FINANCE MODERNIZATION, ALL RELEVANT MODERNIZATION USES (OTHER THAN MANAGEMENT IMPROVEMENTS), FINANCING USES, AND DEVELOPMENT OF NON-DWELLING SPACE WHERE SUCH SPACE IS NEEDED TO ADMINISTER, AND IS OF DIRECT BENEFIT TO A PUBLIC HOUSING PROJECT (I.E. HOUSING DEVELOPED, ACQUIRED, OR ASSISTED BY A PHA UNDER THE 1937 ACT, AND THE IMPROVEMENT OF ANY SUCH HOUSING), INCLUDING THE RESIDENTS. FINANCING DEBT AND FINANCING COSTS (E.G., ORIGINATION FEES, INTEREST) INCURRED BY A PHA FOR DEVELOPMENT OR MODERNIZATION OF PUBLIC HOUSING PROJECTS, INCLUDING MIXED-FINANCE DEVELOPMENT, THE CAPITAL FUND FINANCING PROGRAM (CFFP), AND ANY OTHER USE AUTHORIZED UNDER SECTION 30 OF THE 1937 ACT. MODERNIZATION INCLUDES ALL ELIGIBLE ACTIVITIES EXCEPT FOR DEVELOPMENT AND FINANCING. PHYSICAL WORK IS A MAJOR ACTIVITY AND IS WORK THAT IS DONE ON THE PHYSICAL STRUCTURES, SITE, AND GROUNDS OF A PUBLIC HOUSING PROPERTY OR STRUCTURE. MAJOR PHYSICAL ACTIVITIES INCLUDE DEMOLITION, RECONFIGURATION, EMERGENCY ACTIVITIES, ENERGY EFFICIENCY, NON-ROUTINE MAINTENANCE, PLANNED CODE COMPLIANCE, AND VACANCY REDUCTION. THE MEASURABLE OUTCOME OF THIS GRANT IS THAT HUD WILL BE ABLE TO TRACK THE AMOUNT OF DOLLARS SPENT ON IMPROVEMENTS TO THE STRUCTURES, UNITS, COMMON AREAS, UTILITIES, AND OTHER ELIGIBLE ACTIVITIES. ; EXPECTED OUTCOMES: THE EXPECTED OUTCOMES FOR PUBLIC HOUSING CAPITAL FUNDS OF APPROXIMATELY $3.2 BILLION WILL BE PUT INTO THE DEVELOPMENT, MODERNIZATION, AND FINANCING OF NEARLY 1 MILLION PUBLIC HOUSING UNITS ACROSS ALL 50 STATES AND TERRITORIES. THE PUBLIC HOUSING UNITS ARE UPDATED TO BE DECENT, SAFE, SANITARY AND TO COMPLY WITH FEDERAL HOUSING STANDARDS. PHAS CAN ALSO USE A PORTION OF THE CAPITAL FUNDING FOR MANAGEMENT IMPROVEMENTS OR OPERATING ACTIVITIES INCLUDING SAFETY AND SECURITY COSTS.; INTENDED BENEFICIARIES: THE INTENDED BENEFICIARIES FOR PUBLIC HOUSING CAPITAL FUNDS ARE THE LOW-INCOME PUBLIC HOUSING RESIDENTS.; SUBRECIPIENT ACTIVITIES: THE RECIPIENT DOES NOT INTEND TO SUBAWARD FUNDS.

PUBLIC HOUSING CAPITAL FUND

PUBLIC HOUSING CAPITAL FUND

PERFORM FUNDING SYS

PUBLIC AND INDIAN HOUSING

PUBLIC HOUSING CAPITAL FUND

PUBLIC AND INDIAN HOUSING

PUBLIC HOUSING CAPITAL FUND

PERFORM FUNDING SYS

PUBLIC HOUSING CAPITAL FUND

PURPOSE: THE PUBLIC HOUSING OPERATING FUND (PH OPFUND) PROVIDES OPERATING SUBSIDIES TO HOUSING AUTHORITIES (HAS) TO ASSIST IN FUNDING THE OPERATING AND MAINTENANCE EXPENSES OF THEIR DWELLINGS, IN ACCORDANCE WITH SECTION 9 OF THE U.S. HOUSING ACT OF 1937, AS AMENDED. THE SUBSIDIES ARE REQUIRED TO HELP MAINTAIN SERVICES AND PROVIDE MINIMUM OPERATING RESERVES. THE PH OPFUND IS A $5 BILLION DOLLAR PROGRAM PROVIDING FUNDING TO APPROXIMATELY 6,000 HAS SERVING 1,590,321 PUBLIC HOUSING RESIDENTS IN 902,436 HOUSEHOLDS (44% ARE ELDERLY AND 35% OF RESIDENTS HAVE CHILDREN). INFORMATION ON THE CURRENT OPERATING FUND GRANT PROCESSING CAN BE FOUND AT HTTPS://WWW.HUD.GOV/PROGRAM_OFFICES/PUBLIC_INDIAN_HOUSING/PROGRAMS/PH/AM/FUNDING.; ACTIVITIES TO BE PERFORMED: OPERATING FUNDS ARE USED TO FUND DAY-TO-DAY OPERATIONAL EXPENSES ASSOCIATED WITH PUBLIC HOUSING AS WELL AS THE ADMINISTRATIVE AND PROGRAM IMPLEMENTATION EXPENSES THAT PUBLIC HOUSING AGENCIES (PHAS) ARE REQUIRED TO UNDERTAKE UNDER THE 1937 HOUSING ACT AND PROGRAM REGULATIONS. SUCH ACTIVITIES INCLUDE MANAGEMENT AND OPERATIONS, ROUTINE AND PREVENTATIVE MAINTENANCE, ANTI-CRIME, ANTI-DRUG AND SECURITY ACTIVITIES, OPERATING COSTS FOR PRIVATELY OWNED PUBLIC HOUSING UNITS WITHIN MIXED-FINANCE PROJECTS, ENERGY COSTS, RESIDENT SUPPORTIVE SERVICES, INSURANCE, DEBT SERVICE AND COSTS ASSOCIATED WITH ADMINISTRATION AND PROGRAM IMPLEMENTATION. TURNKEY III PROJECTS ARE FUNDED FOR UNITS UNDER THE FINAL LEASE PURCHASE AGREEMENT FOR CLOSING OUT THE PROGRAM. TO SUPPORT THESE ACTIVITIES, THERE IS CONTINUED MODERNIZATION OF THE INFORMATION TECHNOLOGY PLATFORMS. PHAS HAVE ACCESS TO WEB-BASED PLATFORMS THAT UTILIZE REAL-TIME DATA TO PROVIDE INSIGHT INTO THEIR PORTFOLIOS. PHAS CAN OBTAIN METRICS ON THEIR FUNDING LEVELS, OCCUPANCY RATES, AND THE NUMBER OF FAMILIES SERVED THROUGH RENTAL ASSISTANCE.; EXPECTED OUTCOMES: AS A RESULT OF THE ACTIVITIES PERFORMED, THIS PROGRAM IS EXPECTED TO ASSIST IN FUNDING THE OPERATING AND MAINTENANCE EXPENSES. THIS MAY INCLUDE INCREASED OCCUPANCY IN PUBLIC HOUSING, DECREASED ENERGY COSTS THROUGH REGULAR MAINTENANCE AND ENERGY PERFORMANCE CONTRACTING AND LEVERAGE FEDERAL RESOURCES. IN ADDITION TO ADDRESSING THE DEPARTMENT’S STRATEGIC GOALS OF: • ADDRESSING THE NEED FOR QUALITY AFFORDABLE RENTAL HOMES BY MAINTAINING OR IMPROVING UPON THE 96% OCCUPANCY RATE OF HABITABLE UNITS; • PROMOTING HOUSING AS A PLATFORM TO IMPROVE QUALITY OF LIFE THROUGH SUPPORTIVE SERVICES, CRIME PREVENTION EFFORTS AND RESIDENT ENGAGEMENT ACTIVITIES; AND • HELPING TO BUILD INCLUSIVE COMMUNITIES FREE FROM DISCRIMINATION BY FACILITATING THE IMPLEMENTATION OF AFFIRMATIVELY FURTHERING FAIR HOUSING MEASURES.; INTENDED BENEFICIARIES: THE OPERATING FUND PROVIDES FOR THE OPERATION AND MAINTENANCE OF LOW-INCOME HOUSING PROJECTS TO PHAS/PROJECTS. IT WAS CREATED TO ASSIST HOUSING AUTHORITIES IN PROVIDING DECENT AND SAFE RENTAL HOUSING FOR ELIGIBLE LOW-INCOME FAMILIES OR INDIVIDUALS, THE ELDERLY, AND PERSONS WITH DISABILITIES. A HA DETERMINES ELIGIBILITY BASED ON 1) ANNUAL GROSS INCOME; 2) A PERSON ON WHO IS ELDERLY, A PERSON WITH A DISABILITY, OR AS A FAMILY; AND 3) U.S. CITIZENSHIP OR ELIGIBLE IMMIGRATION STATUS.; SUBRECIPIENT ACTIVITIES: THE SUBRECIPIENT ACTIVITIES ARE UNKNOWN AT THE TIME OF AWARD.

PUBLIC HOUSING CAPITAL FUND

PUBLIC AND INDIAN HOUSING

FY21 SCHOOL VIOLENCE PREVENTION PROGRAM (SVPP)

ASSISTANCE TO FIREFIGHTERS GRANT

PUBLIC AND INDIAN HOUSING

PERFORM FUNDING SYS

CAPITAL AND MANAGEMENT ACTIVITIES (FORMULA)

PUBLIC AND INDIAN HOUSING

ASSISTANCE TO FIREFIGHTERS GRANT

PUBLIC AND INDIAN HOUSING

PUBLIC AND INDIAN HOUSING

PUBLIC AND INDIAN HOUSING

PUBLIC AND INDIAN HOUSING

HOMELESS ASSISTANCE

HOMELESS ASSISTANCE

HOMELESS ASSISTANCE

PUBLIC AND INDIAN HOUSING

ASSISTANCE TO FIREFIGHTERS GRANT PROGRAM

CONTINUUM OF CARE PROGRAM

CAPITAL FUND PROGRAM

CAPITAL FUND PROGRAM

CAPITAL FUND PROGRAM

PUBLIC HOUSING CAPITAL FUND

RBDG RURAL BUSINESS COOP RURAL ENTERPRISE GRANT

PUBLIC HOUSING CAPITAL FUND

CAPITAL FUND PROGRAM

ECOLOGICAL CONNECTIVITY AND SUSTAINABLE LAND-USE IN THE OSTUA DRY FOREST BIOLOGICAL CORRIDOR

CAPITAL FUND PROGRAM

CAPITAL FUND PROGRAM

CAPITAL FUND PROGRAM

FY 2009 RECOVERY ACT JAG PROGRAM

ASSISTANCE TO FIREFIGHTERS GRANT

PERFORM FUNDING SYS

SRSA APPLICATION

ASSISTANCE TO FIREFIGHTERS GRANT

SRSA APPLICATION

RURAL BUSINESS ENTERPRISE GRANTS

APPLICATION FOR SMALL RURAL SCHOOL ACHIEVEMENT PROGRAM

SMALL, RURAL SCHOOL ACHIEVEMENT PROGRAM

MONTCALM/IONIA FINANCIAL AWARENESS ALLIANCE VITA TAX ASSISTANCE PROGRAM

APPLICATION FOR SMALL, RURAL SCHOOL ACHIEVEMENT PROGRAM

APPLICATION FOR SMALL, RURAL SCHOOL ACHIEVEMENT PROGRAM

APPLICATION FOR SMALL, RURAL SCHOOL ACHIEVEMENT PROGRAM

APPLICATION FOR SMALL RURAL SCHOOL ACHIEVEMENT PROGRAM

APPLICATION FOR SMALL, RURAL SCHOOL ACHIEVEMENT PROGRAM

APPLICATION FOR SMALL RURAL SCHOOL ACHIEVEMENT PROGRAM

SRSA APPLICATION

SMALL, RURAL SCHOOL ACHIEVEMENT PROGRAM

COMMUNITY FACILITY 2019 DISASTER GRANTS - TORNADOES FLOODS OTHER

SMALL, RURAL SCHOOL ACHIEVEMENT PROGRAM

SMALL, RURAL SCHOOL ACHIEVEMENT PROGRAM

SMALL, RURAL SCHOOL ACHIEVEMENT PROGRAM

SMALL, RURAL SCHOOL ACHIEVEMENT PROGRAM

SMALL, RURAL SCHOOL ACHIEVEMENT PROGRAM

PUBLIC AND INDIAN HOUSING

COMMUNITY FACILITIES - ECONOMIC IMPACT INITIATIVE GRANTS

MPC DRUG FREE MONTCALM WILL ADDRESS LACK OF SUFFICIENT INFRASTRUCTURE AND RESOURCES TO ADDRESS AND REDUCE SUBSTANCE USE DISORDERS IN YOUTH IN RURAL MONTCALM COUNTY, MICHIGAN.

PUBLIC HOUSING CAPITAL FUND

FLEXIBLE TECHNICAL EDUCATION PATHWAYS IN A BUILDING AUTOMATION TECHNOLOGY PROGRAM -THIS PROJECT AIMS TO SERVE THE NATIONAL INTEREST BY DEVELOPING A BUILDING AUTOMATION TECHNOLOGY PROGRAM TO PREPARE STUDENTS FOR HIGH-DEMAND TECHNICAL CAREERS IN THE WEST-CENTRAL MICHIGAN REGION. IN COLLABORATION WITH INDUSTRY AND OTHER ACADEMIC INSTITUTIONS, COURSES WILL BE DESIGNED AND OFFERED TO TECHNICAL EDUCATION STUDENTS IN SMART HVAC SYSTEMS, ENERGY STORAGE, PRODUCTION CONTROLS IN MANUFACTURING, AND CYBERSECURITY RELATED TO THESE CONTROL SYSTEMS. THE COURSE CURRICULUM WILL BE ALIGNED WITH INDUSTRY CERTIFICATIONS TO BETTER PREPARE STUDENTS FOR THE CURRENT AND FUTURE NEEDS OF EMPLOYERS IN THE REGION. THE RESULT WILL BE AN INCREASE IN THE NUMBER OF SKILLED BUILDING AUTOMATION TECHNICIANS THAT ENTER THE REGIONAL WORKFORCE EACH YEAR OF THE PROJECT. ULTIMATELY, THIS EFFORT AIMS TO FILL SIGNIFICANT GAPS IN THE AVAILABILITY OF CUSTOMIZED TRAINING PROGRAMS THAT MEET THE NEEDS OF INDUSTRY IN TODAY?S DATA AND AUTOMATION DRIVEN SOCIETY. THIS PROJECT TEAM WILL COLLABORATE WITH INDUSTRY TO COMPLETE THE FOLLOWING ACTIVITIES: 1) CREATE BUILDING AUTOMATION TECHNOLOGY COURSES FOR INDUSTRY 4.0 HVAC SYSTEMS, INCLUDING SMART SYSTEMS AND EFFECTIVE DATA STORAGE, 2) DEVELOP ENERGY STORAGE CURRICULUM TO SUPPORT ELECTRIC VEHICLES, 3) PROVIDE STUDENTS WITH PRACTICAL EXPERIENCE IN DATA AND PRODUCTION CONTROLS IN ADVANCED MANUFACTURING AND HVAC SYSTEMS, AND 4) INCLUDE THE CREATION OF CYBERSECURITY CURRICULUM RELATED TO CONTROLS FOR ADVANCED MANUFACTURING AND MUNICIPALITIES. COURSE CURRICULUM WILL PRIORITIZE HANDS-ON LAB ACTIVITIES AND WORK-BASED LEARNING EXPERIENCES AS A WAY TO ACTIVELY ENGAGE STUDENTS IN PRACTICAL AND EFFECTIVE SKILL DEVELOPMENT. A FLEXIBLE PATHWAY MODEL WITH MULTIPLE ON AND OFF RAMPS THAT RESULT IN CERTIFICATES, INDUSTRY CREDENTIALS, APPRENTICESHIPS, DEGREES, AND/OR THE OPTION TO TRANSFER WILL BE IMPLEMENTED. AN EXTERNAL EVALUATION WILL BE CONDUCTED TO ASSESS PROJECT ACTIVITIES AND OUTCOMES WITH A FOCUS ON CONTRIBUTING TO THE BODY OF KNOWLEDGE ON PREPARING SKILLED TECHNICIANS TO SUPPORT THE ADVANCED MANUFACTURING INDUSTRY. A TARGETED DISSEMINATION PLAN WILL BE CARRIED OUT THAT SHARES PROJECT RESULTS WITH OTHER MICHIGAN STATE TWO-YEAR COLLEGES AND AT THE NATIONAL LEVEL THROUGH PRESENTATIONS TO THE BROADER TECHNICAL EDUCATION COMMUNITY. THIS PROJECT IS FUNDED BY THE ADVANCED TECHNOLOGY EDUCATION PROGRAM THAT FOCUSES ON THE EDUCATION OF TECHNICIANS FOR THE ADVANCED-TECHNOLOGY FIELDS THAT DRIVE THE NATION?S ECONOMY. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

ASSISTANCE TO FIREFIGHTERS GRANT

SVC COORD GRANTS 202