Gordon Research Conferences

2024 AFOSR GORDON RESEARCH CONFERENCES AND GORDON RESEARCH SEMINAR BUNDLE SUBMISSION

2025 AFOSR GORDON RESEARCH CONFERENCES AND GORDON RESEARCH SEMINAR BUNDLE SUBMISSION

VISUALIZATION IS THE PROCESS OF TRANSFORMING DATA INTO INSIGHT. INSIGHT ALLOWS FOR THE ANALYSIS AND EXPLORATION OF DATA AT ALL LEVELS OF SCHOLARSHIP INFORMS DECISION MAKING AND FOSTERS ADVANCEMENT IN RESEARCH. IN THIS SPACE WE EXPLORE HOW TO EDUCATE PEOPLE TO BECOME MORE PROFICIENT VISUALIZATION USERS. THIS PROPOSAL IS REQUESTING NASA FUNDING TO SUPPORT TWO BIENNIAL GRC VISUALIZATION IN SCIENCE AND EDUCATION GRC-VSE GATHERINGS THAT PROVIDE A PLATFORM FOR THE DISSEMINATION OF NOVEL CUTTING-EDGE RESEARCH AND FOSTER A RICH EXCHANGE OF IDEAS. THE CONFERENCES AIM TO ATTRACT A WIDE RANGE OF DISCIPLINES FOR WHICH DATA VISUALIZATION PLAYS A SIGNIFICANT ROLE IN KNOWLEDGE DISCOVERY AND EDUCATION TO FACILITATE NETWORKING AND RELATIONSHIP BUILDING AMONG EXPERTS IN THE FIELD AND NEW EMERGING SCHOLARS AND TO FOSTER LIFELONG PROFESSIONAL COLLABORATIONS. TO ADDRESS THESE AIMS THE GOALS OF THE PROPOSED CONFERENCES ARE THREE-FOLD: TO ATTRACT HIGH CALIBER SPEAKERS ACROSS A WIDE RANGE OF DISCIPLINES TO INITIATE AND INSPIRE SCHOLARLY DIALOG; TO BROADEN PARTICIPATION BY AN ECLECTIC TRANSDISCIPLINARY COMMUNITY OF PARTICIPANTS - PARTICULARLY NEW AND EMERGING SCHOLARS - TO SPARK BOUNDARY-SPANNING EXCHANGE OF IDEAS AND SOLUTIONS AND TO CREATE A MECHANISM FOR INNOVATIVE PARTNERSHIPS AND IDEAS TO THRIVE AND DEVELOP BETWEEN CONFERENCES. WE ARE COGNIZANT OF THE EVOLVING ROLE OF VISUALIZATION IN A DATA-DRIVEN WORLD AND THE NEED TO EDUCATE SKILLFUL VISUALIZERS AS WELL AS UNDERSTANDING AND EXPLORING UNCERTAINTY THAT EXISTS IN VISUALIZATION. THE PROPOSED 2019 AND 2021 GRC-VSES ARE DESIGNED TO ENABLE THOUGHT PROVOKING OUT-OF-THE-BOX DIVISIVELY RICH DISCUSSIONS AT THE INTERFACE BETWEEN VISUALIZATION AND EDUCATION. THE 2019 GRC-VSE EDUCATING SKILLFUL VISUALIZERS WILL FOCUS ON HOW TO EDUCATE PEOPLE TO BECOME MORE PROFICIENT VISUALIZATION USERS FROM TWO PERSPECTIVES THOSE WHO CREATE VISUALIZATIONS AND THOSE WHO STRIVE TO CREATE LEARNING EXPERIENCES THAT DEEPEN LEARNERS ABILITY TO EXTRACT INFORMATION AND FORM INFERENCES FROM VISUALIZATIONS. TOPICS FOR THE 2021 GRC-VSE THEME VISUALIZING UNCERTAINTY INCLUDE VISUALLY REPRESENTING THINGS SENSED BUT NOT LITERALLY SEEN MODELING DYNAMICS AND PROCESSES ONLY PARTIALLY DOCUMENTED FACILITATING DECISION MAKING IN THE FACE OF UNCERTAINTY FOR EXAMPLE VISUALIZING POTENTIAL OUTCOMES RANGING FROM MEDICAL PROGNOSES TO CLIMATE CHANGE AND STORYTELLING TO CONTEXTUALIZE AND HUMANIZE UNCERTAINTY. EACH CONFERENCE WILL LEVERAGE SIGNATURE GRC-VSE TRADITIONS: DAILY PLENARY TALKS BY CAREFULLY SELECTED SPEAKERS WHO ARE WORLD LEADERS IN THEIR FIELDS EXTENSIVE DISCUSSIONS ORCHESTRATED BY A FACILITATOR WHO IS ALSO AN EXPERT IN THE THEME OF THE SESSION AND DAILY POSTER SESSIONS WHERE NON-SPEAKER ATTENDEES PRESENT THEIR WORK IN PROGRESS AND RECEIVE FEEDBACK FROM ATTENDING EXPERTS. POSTER SESSIONS ARE SIGNIFICANT OPPORTUNITIES FOR PARTICIPANTS TO MEET AND DISCUSS FUTURE AND POTENTIAL COLLABORATIONS. TO FOSTER SUCH COLLABORATIONS AND THE CROSS-POLLINATION OF IDEAS ACROSS DISCIPLINES PARTICIPANTS ARE ENCOURAGED TO DEVELOP TRANSFORMATIVE PROPOSAL IDEAS FOR VISIONARY MINI-GRANTS. MUCH LIKE AN EXTENDED BRAIN STORMING SESSION PROPOSALS ARE CONCEIVED AND FULLY EXECUTED DURING THE GRC WEEK WITH SUBMISSION ON THE LAST DAY OF THE CONFERENCE. FUNDING FROM MINI-GRANTS SERVE AS SEED FUNDING TO GET THE PROPOSAL IDEA UP AND GOING AND RECIPIENTS RETURN TO THE NEXT CONFERENCE TO DISSEMINATE THEIR RESULTS. WE ARE CONFIDENT THE PROPOSED 2019 AND 2021 GRC-VSES ARE BEFITTING OF THE HIGH QUALITY LONG-STANDING REPUTATION OF GRC. THE TOPICS ARE CURRENT AND BASED ON 2017 GRC-VSE DISCUSSION WORTHY. THE PROPOSED NASA FUNDING OF $197 600 WILL COMPLEMENT FUNDING FROM THE GRC ORGANIZATION AND OTHER SOURCES TO COMPLETE THE FUNDING NEEDED TO FULLY IMPLEMENT THE PROPOSED CONFERENCES. WE ARE EXCITED ABOUT THE PROSPECT OF NASA'S CONTINUED SUPPORT FOR AND PARTICIPATION IN THESE GROUNDBREAKING CONFERENCES.

TAS::57 3600::TAS "2016 GORDON RESEARCH CONFERENCES AND GORDON RESEARCH SEMINAR,"

TAS::57 3600::TAS "2020 GORDON RESEARCH CONFERENCES AFOSR BUNDLE"

2008 CELL BIOLOGY OF THE NEURON

UNDERGRADUATE BIOLOGY EDUCATION AND RESEARCH - A NEW VISION FOR CHANGE: RE-IMAGINING BIOLOGY EDUCATION THROUGH SOCIAL JUSTICE -THIS PROJECT AIMS TO SERVE THE NATIONAL INTEREST BY CONVENING EXPERTS TO SHOWCASE THE LATEST RESEARCH ON BROADENING PARTICIPATION IN UNDERGRADUATE BIOLOGY. THE CONFERENCE IS PART OF THE GORDON RESEARCH CONFERENCE (GRC) PORTFOLIO, WHICH CONSISTS OF HUNDREDS OF CONFERENCES EACH YEAR, THREE OF WHICH ARE IN EDUCATION AREAS. THE UNDERGRADUATE BIOLOGY EDUCATION RESEARCH GRC IS A PREMIER, INTERNATIONAL SCIENTIFIC CONFERENCE FOCUSED ON ADVANCING THE FRONTIERS OF SCIENCE THROUGH THE PRESENTATION OF CUTTING-EDGE AND UNPUBLISHED RESEARCH, PRIORITIZING TIME FOR DISCUSSION AFTER EACH TALK AND FOSTERING INFORMAL INTERACTIONS AMONG SCIENTISTS OF ALL CAREER STAGES. THE UNDERGRADUATE BIOLOGY EDUCATION RESEARCH GRC IS THE FIRST IN THE GRC FAMILY TO FOCUS EXCLUSIVELY ON INVESTIGATING HOW ATTENTION TO SOCIAL JUSTICE ISSUES CAN INFORM IMPROVEMENTS IN UNDERGRADUATE BIOLOGY LEARNING AND TEACHING. THIS CONFERENCE WILL BRING TOGETHER STUDENTS, POSTDOCTORAL SCHOLARS, RESEARCHERS, EDUCATORS, ADMINISTRATORS, POLICY MAKERS, AND PUBLISHERS, PROVIDING A FORUM TO SHARE EMERGING RESEARCH AND PRACTICES THAT PROMOTE INCLUSION, DIVERSITY, EQUITY, ACCESS, AND SOCIAL JUSTICE IN UNDERGRADUATE BIOLOGY EDUCATION ACROSS DISCIPLINES AND SECTORS. THE UNDERGRADUATE BIOLOGY EDUCATION RESEARCH COMMUNITY HAS WITNESSED SIGNIFICANT CHANGES IN ITS DISCOURSE SINCE THE LAST GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR IN 2019. TWO KEY DRIVERS FOR SUCH CHANGES INCLUDE DISRUPTIONS TO THE EDUCATIONAL SYSTEM BY THE COVID-19 PANDEMIC AND INTENSIFIED CONVERSATIONS ABOUT THE IMPORTANT ROLE THAT LEARNING ENVIRONMENTS INFORMED BY A SOCIAL JUSTICE LENS CAN PLAY IN LEADING TO IMPROVED BIOLOGY LEARNING AND TEACHING. A RENEWED RECOGNITION EMERGED FROM THESE DISRUPTIONS: THE COMMUNITY OF UNDERGRADUATE BIOLOGY EDUCATION RESEARCHERS AND PRACTITIONERS VALUES PARTNERING WITH STUDENTS AND SCHOLARS FROM DIFFERENT COMMUNITIES AND INTERSECTIONS OF IDENTITIES TO CREATE INCLUSIVE LEARNING ENVIRONMENTS. THIS RECOGNITION COMPELS RENEWED CONVERSATIONS ON RESEARCH THAT MAY RESHAPE INSTITUTIONAL PRACTICES AND POLICIES, PROPELLING FURTHER ACTION TO IMPLEMENT CHANGES AT INSTITUTIONS ACROSS THE NATION. SPECIFICALLY, THE CONFERENCE INVITES ON-GOING SCHOLARSHIP THAT STRIVES TO CENTER PEOPLE AND COMMUNITIES, FOSTER COLLABORATIONS AND SYSTEMIC CHANGES, AND CREATE NEW VISIONS TOWARD SOCIAL JUSTICE. THIS PROJECT IS FUNDED BY NSF'S IUSE: EDU PROGRAM, WHICH SUPPORTS RESEARCH AND DEVELOPMENT PROJECTS TO IMPROVE THE EFFECTIVENESS OF STEM EDUCATION FOR ALL STUDENTS AND BY THE DIVISION OF BIOLOGICAL INFRASTRUCTURE. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

TAS::57 3600::TAS '2018 GORDON RESEARCH CONFERENCES AND GORDON RESEARCH SEMINARS'

TAS::57 3600::TAS "2015 GORDON RESEARCH CONFERENCES & GORDON RESEARCH SEMINARS" DATED 20 NOV 2014

TAS::57 3600::TAS "2019 GORDON RESEARCH CONFERENCES AND CONFERENCE BUNDLE"

2023 AFOSR GORDON RESEARCH CONFERENCE RESUBMISSION BUNDLE

2020/2022 AUDITORY SYSTEM GRC/GRS

2022 GORDON RESEARCH CONFERENCES AFOSR RESUBMIT BUNDLE

2010 AND 2012 MEMBRANE TRANSPORT PROTEINS

2023 ORIGINS OF SOLAR SYSTEMS GORDON RESEARCH CONFERENCES AND SEMINAR

TAS::57 3600::TAS "ATOMIC & MOLECULAR INTERACTIONS, BIOINSPIRED MATERIALS, BIOMINERALIZATION, DEFECTS IN SEMICONDUCTORS, ELECTRONIC SPECTROSCOPY..."

2023 AFOSR GORDON RESEARCH CONFERENCE BUNDLE

2011 EXCITATORY SYNAPSES AND BRAIN FUNCTION GRC

2010 BIOLOGY OF AGING GORDON RESEARCH CONFERENCE AND/OR GORDON RESEARCH SEMINAR

2012 AGING, BIOLOGY OF GRC & GRS

2012 GREEN CHEMISTRY GRC/GRS

2025 EYE MOVEMENTS GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR - PROJECT ABSTRACT THIS PROPOSAL REQUESTS PARTIAL SUPPORT FOR EYE MOVEMENTS: UNDERSTANDING PERCEPTION, COGNITION, AND ACTION IN HEALTH AND DISEASE, A UNIQUE INTERNATIONAL MEETING ON EYE MOVEMENTS – THEIR UNDERLYING MECHANISMS, ASSOCIATED DISORDERS, AND POSSIBLE TREATMENTS AND APPLICATIONS – THAT IS PART OF THE GORDON RESEARCH CONFERENCE (GRC) SERIES, TO BE HELD JULY 6-11, 2025 AT MOUNT HOLYOKE COLLEGE IN SOUTH HADLEY, MASSACHUSETTS. IT IS PRECEDED BY A GORDON RESEARCH SEMINAR (GRS) ORGANIZED AND HOSTED BY AND FOR TRAINEES TO BE HELD JULY 5-6 2025. THE LONG-TERM GOAL OF THE EYE MOVEMENT GORDON CONFERENCE IS TO INCREASE OUR UNDERSTANDING OF EYE MOVEMENTS TO ADVANCE OUR BASIC SCIENCE KNOWLEDGE AND TO IMPROVE OUR ABILITY TO DIAGNOSE AND TREAT DISORDERS OF OCULAR MOTILITY, GAZE CONTROL, AND VISION, AND ADDITIONALLY TO UNDERSTAND HOW EYE MOVEMENT ABNORMALITIES CAN BE USED TO DIAGNOSE UNDERLYING BRAIN DISEASE AND INJURY. TO ACCOMPLISH THIS GOAL, WE HAVE PUT TOGETHER A PROGRAM THAT REFLECTS THE DIVERSE EXPERTISE AND RESEARCH AREAS THAT INCLUDE THE REMARKABLY BROAD INTELLECTUAL LANDSCAPE OF OUR FIELD. WE WILL ASSEMBLE 38 INVITED SPEAKERS AND DISCUSSANTS THAT SPAN THE FULL RANGE OF SCIENTISTS – FROM TRAINEES TO SENIOR INVESTIGATORS WHOSE RESEARCH SPANS THE FULL BREADTH OF OUR FIELD – FROM THE MOLECULAR LEVEL TO WHOLE SYSTEM BEHAVIOR. WE ANTICIPATE APPROXIMATELY 140 PARTICIPANTS FOR THE FIVE-DAY MEETING IN A SECLUDED AND INCLUSIVE SETTING. THE PROGRAM WILL HAVE 9 SESSIONS ON A WIDE RANGE OF TOPICS INCLUDING: INFANTILE NYSTAGMUS; CONTROL OF FIXATIONAL EYE MOVEMENTS; UNDERSTANDING HOW INDIVIDUAL DIFFERENCES ALTER EYE MOVEMENTS; EYE MOVEMENTS DURING READING AND DURING DECISION-MAKING; HOW NEW CUTTING EDGE APPROACHES ARE OPENING UP NEW UNDERSTANDING OF HOW EYE MOVEMENTS ARE CONTROLLED BY THE BRAIN; HOW VESTIBULAR IMPLANTS CAN ALTER EYE MOVEMENT ABNORMALITIES; AND FINALLY HOW EYE MOVEMENTS CAN BE USED AS BIOMARKERS TO DIAGNOSE CENTRAL NERVOUS SYSTEM DYSFUNCTION. FOUR POSTER SESSIONS WILL FACILITATE SCIENTIFIC EXCHANGE AND MENTORING AMONG ALL PARTICIPANTS. “POWER HOUR: COMMITTED TO INCLUSION AND THE PROFESSIONAL DEVELOPMENT OF WOMEN AND UNDERREPRESENTED MINORITIES IN SCIENCE” WILL PROVIDE AN OPPORTUNITY TO SUPPORT THE PROFESSIONAL GROWTH OF WOMEN AND UNDER-REPRESENTED MINORITIES, AND IS OPEN TO ALL ATTENDEES, AND WILL FOCUS ON BUILDING INCLUSIVE LABORATORY AND RESEARCH PRACTICES. FROM THE ASSOCIATED GRS, WE WILL DRAW SPEAKERS FOR THE MORNING SESSIONS TO GIVE SHORT TALKS TO PROVIDE AN OPPORTUNITY FOR TRAINEES TO PRESENT TO THE ENTIRE CONFERENCE. IN SIZE AND INTENSITY, THE EYE MOVEMENTS GORDON RESEARCH CONFERENCE IS SIGNIFICANT IN OUR FIELD FOR ITS ABILITY TO DISSEMINATE THE LATEST UNPUBLISHED SCIENTIFIC ADVANCES, FOSTER PRODUCTIVE NEW INSIGHTS AND COLLABORATIONS, STIMULATE INTEREST IN EYE MOVEMENT RESEARCH AMONG YOUNG INVESTIGATORS, AND INCREASE THE DIVERSITY OF THE RESEARCH WORKFORCE, ALL WITH THE ULTIMATE GOAL OF ACCELERATING THE DISCOVERY OF DESPERATELY NEEDED NEW THERAPIES FOR PEOPLE WITH DISORDERS OF OCULAR MOTILITY, GAZE CONTROL, AND VISUAL FUNCTION.

2023 EYE MOVEMENTS GRC & GRS - PROJECT SUMMARY/ABSTRACT THIS PROPOSAL REQUESTS PARTIAL SUPPORT FOR A UNIQUE INTERNATIONAL MEETING ON EYE MOVEMENT MECHANISMS, DISORDERS, AND APPLICATIONS IN THE GORDON RESEARCH CONFERENCE SERIES TO BE HELD JULY 9-14, 2023 AT MOUNT HOLYOKE COLLEGE IN SOUTH HADLEY, MASSACHUSETTS, PRECEDED BY A GORDON RESEARCH SEMINAR ORGANIZED AND HOSTED BY AND FOR TRAINEES TO BE HELD JULY 8-9. THE LONG-TERM GOAL OF THE CONFERENCE SERIES IS TO INCREASE OUR UNDERSTANDING OF THE STRUCTURE AND FUNCTION OF THE EYE, ORBIT, AND NEURAL CIRCUITS AND OF THE CHARACTERISTICS OF EYE MOVEMENTS IN VISUAL BEHAVIOR IN HEALTH AND DISEASE WITH THE ULTIMATE GOAL OF MORE EFFECTIVELY DIAGNOSING AND TREATING DISORDERS OF OCULAR MOTILITY, GAZE CONTROL, AND VISION. THE SPECIFIC GOAL OF THE 2023 MEETING IS TO ASSEMBLE A RANGE OF EXPERTISE AND INVESTIGATION THAT SPANS THE REMARKABLY BROAD INTELLECTUAL LANDSCAPE OF OUR FIELD –- FROM MUSCLES TO NERVES, FROM MOTOR CONTROL TO VISUAL PERCEPTION, FROM BEHAVIOR TO NEUROPHYSIOLOGY, FROM DISRUPTIVE STRABISMUS TO SOPHISTICATED COORDINATION OF VISION AND ACTION. THE SPECIFIC AIMS OF THIS MEETING ARE TO CONVENE 39 SPEAKERS AND DISCUSSION LEADERS WITH APPROXIMATELY 140 PARTICIPANTS FOR A FIVE-DAY MEETING IN A SECLUDED SETTING. THE PROGRAM WILL HAVE 9 SESSIONS ON BASIC TOPICS INCLUDING THE DEVELOPMENT OF EXTRAOCULAR MUSCLES, BRAINSTEM MECHANISMS OF EYE MOVEMENT CONTROL, THE ORGANIZATION OF FREE-VIEWING BEHAVIOR, OCULOMOTOR EXPLORATION DURING NAVIGATION, TRANSFORMATIONS ACROSS DIFFERENT REFERENCE FRAMES, DECODING THE CONTENTS OF FIXATIONS, AND BRAINSTEM DECISION MECHANISMS. FOUR POSTER SESSIONS WILL FACILITATE SCIENTIFIC EXCHANGE AND MENTORING AMONG PARTICIPANTS. A POWER HOUR WILL PROVIDE AN OPPORTUNITY TO SUPPORT THE PROFESSIONAL GROWTH OF WOMEN AND UNDER-REPRESENTED MINORITIES. IN SIZE AND INTENSITY, THE EYE MOVEMENTS GORDON RESEARCH CONFERENCE IS SIGNIFICANT IN OUR FIELD FOR ITS ABILITY TO DISSEMINATE THE LATEST SCIENTIFIC ADVANCES, FOSTER PRODUCTIVE NEW INSIGHTS AND COLLABORATIONS, STIMULATE INTEREST IN EYE MOVEMENT RESEARCH AMONG YOUNG INVESTIGATORS, AND INCREASE THE DIVERSITY OF THE RESEARCH WORKFORCE, ALL WITH THE ULTIMATE GOAL OF ACCELERATING THE DELIVERY OF DESPERATELY NEEDED NEW THERAPIES TO PEOPLE WITH DISORDERS OF OCULAR MOTILITY, GAZE CONTROL, AND VISUAL BEHAVIOR.

2019 EYE MOVEMENTS GRC/GRS

2013 EYE MOVEMENTS: THE MOTOR SYSTEM THAT SEES THE WORLD GRC & GRS

2026 BIOLOGY OF ACUTE RESPIRATORY INFECTION GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR - PROJECT SUMMARY THE GORDON RESEARCH CONFERENCE (GRC) TITLED BIOLOGY OF ACUTE RESPIRATORY INFECTION MEETS EVERY 2 YEARS AND FOCUSES ON ADVANCING THE FRONTIERS OF SCIENCE THROUGH PRESENTATION OF CUTTING-EDGE AND UNPUBLISHED RESEARCH IN THE FIELD. THE THEME FOR 2026 IS INTEGRATED PROTECTION ACROSS THE RESPIRATORY TRACT. THE CONFERENCE PROGRAM INCLUDES A WIDE RANGE OF SPEAKERS AND DISCUSSION LEADERS FROM INSTITUTIONS AND ORGANIZATIONS WORLDWIDE, CONCENTRATING ON THE LATEST DEVELOPMENTS IN THE FIELD. THIS BARI-GRC FOCUSES ON BIG PROBLEMS FACING THE FIELD OF ACUTE RESPIRATORY INFECTIONS AND THE EVER-EVOLVING INTERACTIONS BETWEEN PATHOGENS AND HOST AFFECTING HUMAN BIOLOGY. THE GRC IS PRECEDED BY THE GORDON RESEARCH SEMINAR (GRS), A UNIQUE FORUM FOR TRAINEES AND EARLY CAREER SCIENTISTS WITH COMPARABLE LEVELS OF EXPERIENCE TO PRESENT AND EXCHANGE NEW DATA AND CUTTING-EDGE IDEAS. THE GOALS OF THE BIOLOGY OF ACUTE RESPIRATORY INFECTIONS GRC/GRS ARE TO 1) TO CREATE A MULTIDISCIPLINARY PLATFORM HIGHLIGHTING PATHOGENS ACROSS DIFFERENT KINGDOMS, ENABLING DISSEMINATION AND INTERPRETATION OF THE LATEST SCIENTIFIC DISCOVERIES RELATED TO ACUTE RESPIRATORY INFECTIONS WITH A FOCUS ON THE IMPACT ON HUMAN BIOLOGY; 2) TO GENERATE A WELCOMING ENVIRONMENT FOR ALL THAT EMPOWERS THE SCIENTIFIC AND CAREER DEVELOPMENT OF EARLY- STAGE RESEARCHERS. THIS CONFERENCE VENUE FACILITATES MENTORSHIP AND TRAINING OF JUNIOR SCIENTISTS WHO WILL BENEFIT FROM THESE MULTIDISCIPLINARY INTERACTIONS. THE FORMAT (BOTH FORMAL AND INFORMAL), SIZE (< 200 ATTENDEES), AND CONTENT OF THE CONFERENCE (UNPUBLISHED, CUTTING-EDGE, CROSS-DISCIPLINARY) ARE DESIGNED TO MAXIMIZE OPPORTUNITIES FOR EARLY-STAGE INVESTIGATORS TO DIRECTLY INTERACT WITH LEADERS IN THE FIELD, FOSTER COLLABORATIONS AND EMPLOYMENT OPPORTUNITIES IN A COLLEGIAL ENVIRONMENT. WE HAVE DEVELOPED A PROGRAM WITH A UNIFYING THEME OF ONE AIRWAY AND INTEGRATED PROTECTION ACROSS THE ENTIRETY OF THE RESPIRATORY TRACT. WE WILL HIGHLIGHT VARIED PATHOGENS WHICH CAN CAUSE ACUTE PNEUMONIA INCLUDING BACTERIA (INTRACELLULAR AND EXTRACELLULAR), VIRUSES, PARASITES AND FUNGI. THIS MEETING PROVIDES THE SINGLE-MOST COMPREHENSIVE VENUE FOR DISCUSSING THE LATEST ADVANCES IN PNEUMONIA BIOLOGY.

VISUAL SYSTEM DEVELOPMENT GORDON RESEARCH CONFERENCE

2026 AUDITORY SYSTEM GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR - PROJECT SUMMARY HEARING INVOLVES AN EXQUISITELY COMPLEX SET OF MECHANISMS THAT TAKE PLACE IN THE EAR AND THROUGHOUT THE BRAIN, LEADING TO PERCEPTION AND BEHAVIORAL OUTPUTS. PROGRESS IN TREATING HEARING DISORDERS THEREFORE REQUIRES EFFECTIVE CROSS-DISCIPLINARY INTERACTIONS THAT ARE DIFFICULT TO ACHIEVE WITH CONVENTIONAL CONFERENCE FORMATS THAT ARE EITHER LARGE AND WIDE-RANGING OR SMALL AND NARROWLY FOCUSED. SINCE 2008, THE BIENNIAL AUDITORY SYSTEM GORDON RESEARCH CONFERENCE (GRC) AND THE ASSOCIATED, TRAINEE-FOCUSED AUDITORY SYSTEM GORDON RESEARCH SEMINAR (GRS) HAVE MET THIS CRITICAL NEED BY PROVIDING A UNIQUE, SMALL CONFERENCE EXPERIENCE THAT EMPOWERS SCIENTISTS, CLINICIAN SCIENTISTS, AND TRAINEES FROM ACROSS THE BREADTH OF THE AUDITORY FIELD TO SHARE UNPUBLISHED RESULTS, DISCUSS CUTTING-EDGE IDEAS, AND FORM NEW CROSS-DISCIPLINARY COLLABORATIONS. A KEY INNOVATION OF THE AUDITORY SYSTEM GRC SERIES IS THE GRC CONFERENCE FORMAT IN WHICH CONFEREES ACROSS ALL CAREER STAGES AND AUDITORY SUBFIELDS CONVERGE ON A SMALL COLLEGE CAMPUS, ATTEND THE SAME TALKS AND POSTER SESSIONS, AND HAVE AMPLE TIME TO DISCUSS NEW IDEAS AND FORM NEW COLLABORATIONS. THE PROGRAM SCHEDULE WITH NO OVERLAPPING SESSIONS AND THE CONFERENCE SETTING BREAK DOWN BARRIERS BETWEEN CAREER STAGES AND SUBDISCIPLINES. THIS FACILITATES CONVERSATIONS THAT READILY EXTEND ACROSS DAYS AND LEADS TO LASTING IMPACTS ON RESEARCH PROGRESS AND THE CAREERS OF CONFEREES. THE NEXT TWO INSTALLMENTS OF THE AUDITORY SYSTEM GRC AND GRS WILL TAKE PLACE IN 2026 AND 2028 AND WILL FEATURE KEYNOTE TALKS FROM 40+ SPEAKERS REPRESENTING THE BREADTH OF CUTTING-EDGE RESEARCH FROM ACROSS THE AUDITORY FIELD AND A RANGE OF CAREER STAGES. THE GRC AND GRS WILL ALSO FEATURE DAILY POSTER SESSIONS, PROVIDING ALL CONFEREES THE OPPORTUNITY TO SHARE THEIR LATEST RESULTS AND ENGAGE IN DEEP CONVERSATIONS ABOUT KEY AUDITORY RESEARCH QUESTIONS. THE 2026 GRC WILL FOCUS ON MECHANISMS, PERCEPTION, AND RESTORATION IN THE AUDITORY SYSTEM, AND THE TRAINEE-LED 2026 GRS WILL FOCUS ON SOUND TRANSFORMED: THE GENETIC AND NEURAL BASIS OF HEARING. SIMILARLY BROAD AND TIMELY THEMES WILL BE SELECTED FOR THE 2028 AUDITORY GRC AND GRS. CROSS-DISCIPLINARY EXCHANGE OF NOVEL RESULTS IS FACILITATED BY ALTERNATING THEMES THROUGHOUT THE CONFERENCE, DEDICATED DISCUSSION PERIODS FOLLOWING EACH TALK, AND ABUNDANT OPPORTUNITIES EACH DAY FOR DISCUSSION AND DEBATE AMONG CONFEREES. THE SCIENTIFIC AND PROFESSIONAL DEVELOPMENT OF GRADUATE STUDENTS AND POSTDOCTORAL FELLOWS IS A KEY EMPHASIS OF THE CONFERENCE. THE TRAINEE-LED GRS FEATURES 10 TRAINEE TALKS SELECTED FROM ABSTRACT SUBMISSIONS, 2 TRAINEE POSTER SESSIONS, A KEYNOTE TALK FROM A TRAILBLAZING JUNIOR PROFESSOR, AND A MENTORSHIP COMPONENT. TRAINEES WILL ALSO BE SELECTED TO GIVE 8 OR MORE TALKS DURING THE GRC, AND SPECIAL EFFORTS WILL BE MADE TO ENSURE TRAINEE INTERACTIONS WITH FACULTY THROUGHOUT THE GRC. TO RECOGNIZE TRAINEE RESEARCH AND PROMOTE TRAINEE PARTICIPATION, TRAINEE TRAVEL AWARDS AND GRS REGISTRATION WAIVERS WILL BE PROVIDED. GRC AND GRS OUTCOMES WILL BE ASSESSED WITH IN-DEPTH SURVEYS COMPLETED DURING THE FINAL MEETING DAY.

THIS PROPOSAL REQUESTS FUNDING OF $30,000 FROM NASA TO SUPPORT REGISTRATION AND/OR TRAVEL COSTS OF PARTICIPANTS, SUCH AS BUT NOT LIMITED TO WORLD-REN

GORDON RESEARCH CONFERENCE ON SCIENCE AND TECHNOLOGY POLICY

2020/2022 ALCOHOL AND THE NERVOUS SYSTEM GORDON RESEARCH CONFERENCE & GORDON RESEARCH SEMINAR

2026 NEURAL MECHANISMS OF ACOUSTIC COMMUNICATION GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR - PROJECT SUMMARY IN ITS THIRD INSTALLMENT, THE NEURAL MECHANISMS OF ACOUSTIC COMMUNICATION (NMAC) GORDON RESEARCH CONFERENCE (GRC), ALONG WITH THE ASSOCIATED GORDON RESEARCH SEMINAR (GRS), WILL CONVENE ON MAY 30-JUNE 5, 2026 AT THE JORDAN RIVER HOTEL IN SUNDAY RIVER, MAINE TO DISCUSS AND DEBATE NEW FINDINGS IN COMMUNICATION RESEARCH AND RELATED FIELDS. THE NMAC GRC WILL ENABLE INVESTIGATORS OF ALL RANKS WITH WIDE-RANGING EXPERTISE AND FROM A VARIETY OF SUB-FIELDS TO INTERACT, LEVERAGING THE INTIMATE SIZE AND EXTENDED DISCUSSION TIME OF THE TRADITIONAL GRC FORMAT TO ENABLE FERTILE SCIENTIFIC DISCOURSE. THIS MEETING FULFILLS A UNIQUE NICHE WITHIN THE LANDSCAPE OF EXISTING CONFERENCES THROUGH ITS FOCUS ON COMPARATIVE AND MECHANISTIC APPROACHES TO THE STUDY OF NEURAL CIRCUITS THAT MEDIATE INTERACTIVE VOCAL BEHAVIOR ACROSS TAXA THAT REPRESENT 800 MILLION YEARS OF EVOLUTION. THE INTERACTIVE ABILITY TO EXCHANGE INFORMATION IS A CENTRAL AND DEFINING FEATURE OF ALL COMMUNICATION SYSTEMS AND HELPS ORGANIZE SOCIAL BEHAVIOR. AS SUCH, A COMPARATIVE APPROACH TO THE STUDY OF THE NEURAL MECHANISMS UNDERLYING ACOUSTIC COMMUNICATION LENDS INSIGHT INTO GENERAL MECHANISMS OF NEURAL FUNCTION, LEADS TO THE DEVELOPMENT OF NOVEL ANALYTICAL AND EXPERIMENTAL TECHNIQUES AND PAVES THE WAY TO NOVEL TREATMENTS OF DYSFUNCTION IN HUMAN COMMUNICATION SYSTEMS. THE 2026 NMAC HAS THREE SPECIFIC AIMS: 1) TO ADVANCE ACOUSTIC COMMUNICATION RESEARCH BY OFFERING AN ENVIRONMENT THAT ENCOURAGES QUESTIONS AND DISCUSSION, CHALLENGES CURRENT THINKING, IDENTIFIES OPEN QUESTIONS, AND PROVIDES OPPORTUNITIES FOR NEW COLLABORATIONS; 2) TO CREATE A UNIQUE FORUM FOR INTERACTION FOR RESEARCHERS WITH DIFFERENT PERSPECTIVES ON ACOUSTIC COMMUNICATION AND BREAK DOWN BOUNDARIES THAT EXIST BETWEEN COMMUNITIES FOCUSED ON DIFFERENT MODEL SYSTEMS, BRAIN REGIONS, AND RESEARCH APPROACHES; AND 3) TO EDUCATE NEW AND EARLY CAREER INVESTIGATORS. TO PROVIDE GREATER OPPORTUNITIES FOR IMPACTFUL JUNIOR SCIENTISTS, WE ARE INCLUDING “NEXT GENERATION TALKS” WHERE THE CHAIRS WILL PICK 4 GRADUATE STUDENTS OR POSTDOCS FROM THE GRS TO PRESENT AT THE GRC MEETING. IN ADDITION, AT LEAST 2 TALKS PER SESSION WILL BE SELECTED FROM SUBMITTED ABSTRACTS WITH THE AIM TO FEATURE EARLY CAREER RESEARCHERS, INCLUDING GRADUATE STUDENTS, POSTDOCS, AND ASSISTANT PROFESSORS. MENTORSHIP OPPORTUNITIES WILL INCLUDE THEMED LUNCHES WHERE 1-3 SCIENTISTS INFORMALLY DISCUSS TOPICS OF INTEREST WITH GRADUATE STUDENTS AND POSTDOCTORAL SCIENTISTS, SUCH AS SECURING A POSTDOCTORAL OR FACULTY JOB, STARTING A LABORATORY, AND MAINTAINING A HEALTHY WORK-LIFE BALANCE. TAKEN TOGETHER, NMAC AIMS TO CREATE CONVERSATIONS THAT WILL ACHIEVE A MECHANISTIC AND UNIFYING UNDERSTANDING OF THE NEURAL UNDERPINNINGS OF ACOUSTIC COMMUNICATION BY UNCOVERING BROADLY RELEVANT ALGORITHMS AND GENERAL PRINCIPLES. THESE EXCHANGES WILL ADVANCE ACOUSTIC COMMUNICATION RESEARCH BY ENCOURAGING NEW IDEAS AND COLLABORATIONS, HIGHLIGHTING EXCELLENCE IN THE FIELD, AND INSPIRING THE NEXT GENERATION OF SCIENTISTS TO ACCELERATE THE PACE OF DISCOVERY AND TRANSLATION TO THE CLINIC, CONSISTENT WITH THE MISSION OF NIH.

2006 DENDRITES: MOLECULES, STRUCTURE AND FUNCTION (GORDON RESEARCH CONFERENCE)

CATCHMENT SCIENCE: INTERACTIONS OF HYDROLOGY, BIOLOGY AND GEOCHEMISTRY

2011 OXIDATIVE STRESS AND DISEASE GORDON RESEARCH CONFERENCE

2026 VISUAL SYSTEM DEVELOPMENT GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR - PROJECT SUMMARY THE 2026 GORDON RESEARCH CONFERENCE (GRC) AND GORDON RESEARCH SEMINAR (GRS) ON VISUAL SYSTEM DEVELOPMENT ARE A PAIRED SET OF BIENNIAL MEETINGS THAT BRING TOGETHER INVESTIGATORS STUDYING DEVELOPMENT, DISEASE, AND EVOLUTION OF THE VISUAL SYSTEM. OVER THE YEARS, THESE MEETINGS HAVE PROVIDED AN EXCITING AND UNIQUE FORUM IN WHICH TO EXPLORE THE SIMILARITIES AND DIFFERENCES UNDERLYING VISUAL SYSTEM DEVELOPMENT AND FUNCTION ACROSS A BROAD RANGE OF SPECIES. THE GOAL OF THESE MEETINGS IS TO FOSTER AN APPRECIATION OF COMMON PRINCIPLES THAT MEDIATE THE CONSTRUCTION AND FUNCTION OF THE VISUAL SYSTEM IN DIVERSE ORGANISMS, AND TO SHARE THE LATEST EXCITING NEW IDEAS AND FINDINGS ON THIS TOPIC. BY INCLUDING SESSIONS THAT HIGHLIGHT EMERGING TOPICS WITH TRANSLATIONAL IMPACT, SUCH AS “RETINAL STEM CELLS, REPAIR, AND REGENERATION”, AND “DEVELOPMENTAL DISORDERS, DISEASES, AND AGING OF THE VISUAL SYSTEM”, THE MEETING IS ALSO EXPANDING ITS SCOPE AND STIMULATING CROSSTALK BETWEEN DEVELOPMENTAL BIOLOGISTS AND INVESTIGATORS FOCUSED ON TRANSLATIONAL ASPECTS OF VISION SCIENCE. THE GRS PROVIDES A UNIQUE PLATFORM FOR STUDENTS AND POSTDOCTORAL RESEARCH FELLOWS IN THE VISUAL RESEARCH FIELD TO SHARE CURRENT, UNPUBLISHED RESEARCH AMONGST THEIR PEERS AND RECEIVE CAREER MENTORSHIP IN THE VISION SCIENCE FIELD. THE FORMAT OF THE GRC AND GRS MEETINGS PROVIDES A HIGHLY INTERACTIVE AND STIMULATING VENUE FOR CROSS- FERTILIZATION OF IDEAS AND DEVELOPMENT OF NEW COLLABORATIONS. THE VISUAL SYSTEM DEVELOPMENT GRC HAS ESTABLISHED A REPUTATION AS THE LEADING CONFERENCE IN ITS FIELD, AND IT IS THE ONLY MEETING ON THE TOPIC THAT BRINGS TOGETHER VISION RESEARCHERS WORKING ON THE FULL RANGE OF EXPERIMENTAL SYSTEMS IN THE FIELD, RANGING FROM DROSOPHILA TO HUMAN. THE CURRENT PROPOSAL REQUESTS FUNDS TO HELP DEFRAY CONFERENCE FEES FOR ATTENDEES AT BOTH MEETINGS. THE VISUAL SYSTEM GRC AND GRS WILL FEATURE SCIENTISTS AT THE CUTTING EDGE OF THE FIELD, WITH CAREFUL ATTENTION TAKEN TO ENSURE INVOLVEMENT OF RESEARCHERS AROUND THE WORLD, WITH PARTICIPATION FROM SCIENTISTS AT ALL STAGES OF THEIR CAREERS.

2016 AND 2018 ALCOHOL AND THE NERVOUS SYSTEM GRC

2024 NEURAL MECHANISMS OF ACOUSTIC COMMUNICATION GORDON RESEARCH CONFERENCE AND SEMINAR - PROJECT SUMMARY IN ITS SECOND INSTALLMENT, THE NEURAL MECHANISMS OF ACOUSTIC COMMUNICATION (NMAC) GORDON RESEARCH CONFERENCE, WHICH THIS YEAR WILL ALSO INCLUDE AN ASSOCIATED GORDON RESEARCH SEMINAR (GRS), WILL CONVENE ON MAY 18-24, 2024, AT THE JORDAN RIVER HOTEL IN SUNDAY RIVER, MAINE TO DISCUSS AND DEBATE NEW FINDINGS IN COMMUNICATION RESEARCH AND RELATED FIELDS. THE NMAC GRC WILL ENABLE INVESTIGATORS OF ALL RANKS WITH WIDE-RANGING EXPERTISE AND FROM A VARIETY OF SUB-FIELDS AND BACKGROUNDS TO INTERACT, LEVERAGING THE INTIMATE SIZE AND EXTENDED DISCUSSION TIME OF THE TRADITIONAL GRC FORMAT TO ENABLE FERTILE SCIENTIFIC DISCOURSE. THIS MEETING FULFILLS A UNIQUE NICHE WITHIN THE LANDSCAPE OF EXISTING CONFERENCES THROUGH ITS FOCUS ON COMPARATIVE AND MECHANISTIC APPROACHES TO THE STUDY OF NEURAL CIRCUITS THAT MEDIATE INTERACTIVE ACOUSTIC BEHAVIOR ACROSS TAXA THAT REPRESENT 800 MILLION YEARS OF EVOLUTION. THE INTERACTIVE ABILITY TO EXCHANGE INFORMATION IS A CENTRAL AND DEFINING FEATURE OF ALL COMMUNICATION SYSTEMS AND HELPS ORGANIZE SOCIAL BEHAVIOR. AS SUCH, A COMPARATIVE APPROACH TO THE STUDY OF THE NEURAL MECHANISMS UNDERLYING ACOUSTIC COMMUNICATION LENDS INSIGHT INTO GENERAL MECHANISMS OF NEURAL FUNCTION, LEADS TO THE DEVELOPMENT OF NOVEL ANALYTICAL AND EXPERIMENTAL TECHNIQUES AND PAVES THE WAY TO NOVEL TREATMENTS OF DYSFUNCTION IN HUMAN COMMUNICATION SYSTEMS. THE 2024 NMAC HAS THREE SPECIFIC AIMS: 1) TO ADVANCE ACOUSTIC COMMUNICATION RESEARCH BY OFFERING AN ENVIRONMENT THAT ENCOURAGES QUESTIONS AND DISCUSSION, CHALLENGES CURRENT THINKING, AND PROVIDES OPPORTUNITIES FOR NEW COLLABORATIONS; 2) TO CREATE A UNIQUE FORUM FOR INTERACTION FOR RESEARCHERS FROM A DIVERSITY OF COMMUNICATION SYSTEMS AND BREAK DOWN BOUNDARIES BETWEEN COMMUNITIES FOCUSED ON DIFFERENT MODEL SYSTEMS, BRAIN REGIONS, RESEARCH APPROACHES; AND 3) TO EDUCATE NEW AND EARLY CAREER INVESTIGATORS. TO PROVIDE GREATER OPPORTUNITIES FOR IMPACTFUL JUNIOR SCIENTISTS, WE ARE INTRODUCING THE “NEXT GENERATION TALKS” SERIES WHERE THE CHAIRS WILL PICK 4 GRADUATE STUDENTS OR POSTDOCS FROM THE GRS TO PRESENT AT ONE OF THE SESSIONS OF THE GRC MEETING. IN ADDITION, ONE TALK PER SESSION WILL BE SELECTED FROM SUBMITTED ABSTRACTS WITH THE AIM TO INCLUDE SPEAKERS FROM LESS REPRESENTED BACKGROUNDS. MENTORSHIP OPPORTUNITIES WILL INCLUDE THEMED LUNCHES WHERE 1-3 SCIENTISTS INFORMALLY DISCUSS TOPICS OF INTEREST WITH GRADUATE STUDENTS AND POSTDOCTORAL SCIENTISTS, SUCH AS SECURING A POSTDOCTORAL OR FACULTY JOB, STARTING A LABORATORY, AND MAINTAINING A HEALTHY WORK-LIFE BALANCE. TAKEN TOGETHER, NMAC AIMS TO CREATE CONVERSATIONS THAT WILL ACHIEVE A MECHANISTIC AND UNIFYING UNDERSTANDING OF THE NEURAL UNDERPINNINGS OF ACOUSTIC COMMUNICATION BY UNCOVERING BROADLY RELEVANT ALGORITHMS. THESE EXCHANGES WILL ADVANCE ACOUSTIC COMMUNICATION RESEARCH BY ENCOURAGING NEW IDEAS AND COLLABORATIONS, HIGHLIGHTING DIVERSITY IN THE FIELD, AND INSPIRING THE NEXT GENERATION OF SCIENTISTS TO ACCELERATE THE PACE OF DISCOVERY AND TRANSLATION TO THE CLINIC, CONSISTENT WITH THE MISSION OF NIH.

2017 AND 2019 ALCOHOL-INDUCED END ORGAN DISEASES GORDON RESEARCH CONFERENCE

2017 EYE MOVEMENTS GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR

2015 EYE MOVEMENTS GRC/GRS

2025 STRESS PROTEINS IN GROWTH, DEVELOPMENT AND DISEASE GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR - PROJECT SUMMARY PROTEIN HOMEOSTASIS (OFTEN REFERRED TO AS PROTEOSTASIS) IS THE EQUILIBRIUM IN OUR CELLS BETWEEN THE TIMELY MAKING AND DEGRADATION OF PROTEINS TO ENSURE FUNCTION AND TO AVOID ACCUMULATION OF TOXIC SPECIES. BOTH THE CONTINUOUSLY CHANGING NORMAL PHYSIOLOGY AND A MANIFOLD OF EXTERNAL CHALLENGES, INCLUDING ACUTE FORMS OF STRESS (TEMPERATURE, OXIDATION AND INFLAMMATION) OR CHRONIC CONDITIONS (EXPRESSION PROTEINS FROM INHERITED GENE MUTATIONS OR DUE TO SOMATIC MUTATIONS DURING AGING) REQUIRE A HIGHLY ORCHESTRATED AND VERSATILE PROTEIN QUALITY CONTROL SYSTEMS THAT ENSURES THAT THIS BALANCE IS WELL-MAINTAINED. THIS NETWORK NOT ONLY CONCERNS CHAPERONES AND PROTEIN DEGRADATION SYSTEMS (BOTH PROTEASOMAL AND LYSOSOMAL) THAT ASSIST IN FOLDING AND DISPOSAL, BUT ALSO COORDINATED REGULATION OF THE MAKING OR HALTING OF PROTEIN SYNTHESIS (BOTH AT THE TRANSCRIPTIONAL AND TRANSLATIONAL LEVEL). IMPORTANTLY, IF PROTEIN HOMEOSTASIS COLLAPSES, A PROGRESSIVE CASCADE OF PROTEIN AGGREGATION IS INITIATED DRIVING THE AGE-RELATED DECLINE IN CELLULAR FUNCTIONS AND DEGENERATION OF TISSUES, ULTIMATELY LEADING TO LOSS OF ORGANISMAL RESILIENCE. WHILST PROTEIN AGGREGATION IS BEST KNOWN AS THE DRIVER OF NEURODEGENERATIVE DISEASES, IT IS BECOMING CLEAR THAT IT IS ALSO A ROOT CAUSE FOR SEVERAL OTHER AGE-RELATED DISEASES INCLUDING CARDIOMYOPATHIES, MUSCULAR DYSTROPHIES AND TYPE-2 DIABETES. INVERSELY, THE ADAPTIVE CAPACITY OF CELLS TO RESTORE IMBALANCES IN THE MAKING OF (FAULTY) PROTEINS BY ADJUSTING THEIR PROTEIN QUALITY CONTROL SYSTEMS SUSTAINS THEIR VITALITY DURING CARCINOGENESIS. THE 2025 GRC ON STRESS PROTEINS IN GROWTH, DEVELOPMENT AND DISEASE , SCHEDULED FOR JULY 6-11, 2025, AT THE JORDAN HOTEL AT SUNDAY RIVER. THIS 12TH INSTALLMENT WILL BE HELD UNDER THE SUBTITLE “TARGETING THE INTEGRATED PQC NETWORK TO COMBAT AGEING AND AGE-RELATED DISEASES” AND PROMISES TO COVER THE CUTTING EDGE ADVANCES IN THE FIELD OF PROTEIN HOMEOSTASIS, RANGING FROM THE BASIC REGULATORY MECHANISMS THAT DRIVE THEIR VERSATILE AND ADAPTIVE RESPONSE TO CHANGING CONDITIONS, TO HOW COMPONENTS OF PROTEIN QUALITY CONTROL SYSTEMS ACT AT THE MOLECULAR LEVEL TO HANDLE (MISFOLDED) PROTEINS, UP TO (PHARMACOLOGICAL) INTERVENTION STRATEGIES THAT BOOST OR INHIBIT THESE SYSTEMS TO COMBAT (AGE-RELATED) DISEASES TO IMPROVE HEALTHY AGING. THE CONFERENCE WILL BEGIN WITH THE GRADUATE RESEARCH SEMINAR (GRS) ON JULY 5-6, NURTURING THE NEXT GENERATION OF INVESTIGATORS IN OUR FIELD. EXCEPTIONAL GRS PARTICIPANTS, SELECTED BY THE GRS ATTENDEES, WILL SHOWCASE THEIR RESEARCH THROUGH ORAL PRESENTATIONS AT THE MAIN CONFERENCE. MOREOVER, DEDICATED SESSIONS AND ROUNDTABLE DISCUSSIONS WILL EMPOWER JUNIOR INVESTIGATORS, EMPHASIZING INCLUSIVITY AND DIVERSITY IN SCIENTIFIC PURSUITS. FINALLY, A POWERHOUR SESSION, FOCUSED ON DIVERSITY, WILL COMPLETE THIS CONFERENCE. OUR MEETINGS HAVE ALWAYS BLENDED CUTTING-EDGE SCIENCE, ON A DEEPER UNDERSTANDING OF THE MAINTENANCE OF PROTEIN HOMEOSTASIS, WITH A WARM AND INCLUSIVE ATMOSPHERE, FOSTERING COLLABORATIONS AND INVALUABLE CONNECTIONS FOR FUTURE CAREERS. LED BY DR. HARM H. KAMPINGA (CHAIR) AND DR. PATRICIJA VAN OOSTEN- HAWL (CO-CHAIR), THIS GRC PROMISES TO UPHOLD ITS REPUTATION AS A PREMIER GATHERING IN THE FIELD, CHARTING THE COURSE FOR FUTURE ADVANCEMENTS IN PROTEIN HOMEOSTASIS RESEARCH.

2024 CYCLIC NUCLEOTIDE PHOSPHODIESTERASES GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR - PROJECT SUMMARY/ABSTRACT THE 2024 GORDON RESEARCH CONFERENCE ON CYCLIC NUCLEOTIDE PHOSPHODIESTERASES (PDES) WILL EXPLORE BLEEDING-EDGE RESEARCH DRIVING THE FIELD TO RECONCEPTUALIZE THE FUNDAMENTAL BIOLOGY AND THERAPEUTIC POTENTIAL OF TARGETS WITHIN THE CAMP/CGMP CYCLIC NUCLEOTIDE SIGNALING CASCADES. THESE PATHWAYS, WHICH ARE REGULATED BY PDES, MODULATE A NUMBER OF CRITICAL PHYSIOLOGICAL PROCESSES ACROSS THE LIFESPAN. AS SUCH, TARGETS WITHIN THESE SIGNALING CASCADES HAVE LONG BEEN OF HIGH INTEREST TO DRUG DISCOVERY EFFORTS, PARTICULARLY IN THE CONTEXT OF AGING-RELATED DISEASES. INDEED, WE ARE SEEING THE FRUITS OF OUR LABOR WITH MANY PDE INHIBITORS IN THE CLINIC TODAY AND MANY MORE IN ACTIVE CLINICAL TRIALS. THE PROGRAM WILL INCLUDE STATE-OF-THE-ART APPROACHES THAT SHED NEW LIGHT ON THE PHYSIOLOGY OF THESE CASCADES AND REVEAL SOPHISTICATED MECHANISMS BY WHICH TARGETS MAY BE MANIPULATED FOR THERAPEUTIC GAIN. A FRESH SYSTEMS-LEVEL APPROACH WILL BE TAKEN, WITH A GIVEN SESSION FOCUSING ON THE SAME TARGET IN THE CONTEXT OF DIFFERENT ORGANS/DISEASES. BY BRINGING TOGETHER ACADEMIC AND INDUSTRIAL SCIENTISTS AT ALL CAREER STAGES FROM THE FIELDS OF AGING, CANCER, CARDIOLOGY, IMMUNOLOGY & INFLAMMATION, NEUROSCIENCE/PSYCHIATRY, PULMONOLOGY, ETC., THE CONFERENCE HOPES TO ADVANCE DRUG DISCOVERY EFFORTS BY STIMULATING DEEP DISCUSSION OF THE POTENTIAL FOR EFFICACY VERSUS SIDE EFFECTS. THE GRC WILL INCLUDE 62 SPEAKERS (54 INVITED AND 8 CHOSEN FROM ABSTRACTS) AND 2 INTERACTIVE POSTER SESSIONS. WE INVITED SUCH A HIGH PROPORTION OF OUR SPEAKERS TO DRAMATICALLY INCREASE THE DIVERSITY OF OUR SPEAKER POOL (51.6% FEMALE, 14.5% UNDERREPRESENTED MINORITY BY NIH AND/OR GRC DEFINITIONS, 21% TRAINEES). THE PRE-MEETING SEMINAR (GRS) WILL HAVE FURTHER TALK AND POSTER OPPORTUNITIES FOR UNDERGRADUATE AND GRADUATE STUDENTS, POST-BACS, AND POST-DOCS, AS WELL AS A CAREER/MENTORING PANEL. A ‘POWER HOUR’ IN THE MAIN MEETING WILL FOCUS ON ADDRESSING WAYS WE ALL CAN IMPROVE DIVERSITY AND INCLUSION IN SCIENCE. WE AIM TO FOSTER AN INTERACTIVE, FRIENDLY ENVIRONMENT IN WHICH IDEAS CAN BE FREELY EXCHANGED INDEPENDENTLY OF BACKGROUND OR SENIORITY. THE GRC PROGRAM WILL BE ORGANIZED INTO NINE MORNING AND EVENING SESSIONS ENTITLED: (1) WHAT WE THOUGHT WE KNEW AND WHAT (WE THINK) WE KNOW NOW, (2) SHINING A LIGHT ON CYCLIC NUCLEOTIDE SIGNALING PATHWAYS: ADVANCEMENTS IN BIOSENSORS AND STRUCTURE, (3) THE 'INS' AND 'OUTS' OF CYCLIC NUCLEOTIDE SIGNALING: INTRACELLULAR CYCLASES AND EXTRACELLULAR CYCLIC NUCLEOTIDE SIGNALING, (4) DO UNTO THOSE DOWNSTREAM AS YOU WOULD HAVE THOSE UPSTREAM DO UNTO YOU: CYCLIC NUCLEOTIDE EFFECTORS, (5) BUGGIN' OUT WITH CYCLIC NUCLEOTIDE SIGNALING: NON-MAMMALIAN PDES, (6) 1 IS NOT THE LONELIEST NUMBER: PDE1, PDE10, AND PDE11, (7) WHY ARE WE SO SCARED? BECAUSE PDE7, 8, 9, (8) THE MOST EXPLORED: PDE4, AND (9) TO CROSS OR NOT TO CROSS THE STREAMS, THAT IS THE QUESTION: PDE2 AND PDE3 CROSSTALK. WITH AFTERNOONS DEDICATED TO SOCIAL ACTIVITIES THAT FACILITATE NETWORKING AND IDEA EXCHANGE, THIS GRC/GRS IS SURE TO ADVANCE THE SCIENCE OF THIS EXCITING FIELD, CREATE CROSS-DISCIPLINARY COLLABORATIONS, AND INSPIRE THE NEXT GENERATION OF SCIENTISTS.

WE REQUEST HERE TO SUPPORT A GORDON CONFERENCE AND AN ASSOCIATED GORDON RESEARCH SEMINAR ON THE ORIGINS OF LIFE TO BE HELD JAN 13-19 2018 IN GALVESTON TEXAS. THIS CONFERENCE IS ONE OF THE ?BIG THREE? INTERNATIONAL ASTROBIOLOGY CONFERENCES HOSTED IN THE US ALONG WITH ABSCICON AND ISSOL (OCCASIONALLY) AND AS SUCH IS ONE OF THE PRINCIPAL VENUES FOR DISSEMINATING RECENT FINDINGS IN ASTROBIOLOGY. THE GORDON CONFERENCE IS BY DESIGN MUCH SMALLER THAN ABSCICON AND ISSOL AND FOCUSES ON THE PRESENTATION OF NEW AND UNPUBLISHED RESEARCH IN BOTH TALK AND POSTER FORM. THE ORIGINS OF LIFE GORDON CONFERENCE HAS BEEN GOING SINCE 1982 AND HAS SPAWNED MANY COLLABORATIONS HOSTED SEVERAL NOBEL LAUREATES AND FEATURED MULTIPLE DEBATES IN THE FIELD. IN 2018 SEVERAL NASA RESEARCHERS AND EXOBIOLOGY-FUNDED PIS ARE SCHEDULED TO PRESENT AND KEY NASA MISSIONS INCLUDING OSIRIS-REX WILL BE ABLE TO SHARE THEIR FINDINGS AND MISSION PLANS AS THE KEYNOTE TALK WITH THE ASTROBIOLOGY COMMUNITY. THE SUBJECT THEME THIS YEAR IS "FROM MILIEU TO EVOLUTION" AND COVERS NASA-RELEVANT SUBJECTS SUCH AS THE TRANSITION OF PREBIOTIC CHEMISTRY TO THE ORIGIN OF LIFE THE ORGANIC INVENTORY OF THE EARLY EARTH INCLUDING BY DELIVERY OF EXTRATERRESTRIAL MATERIAL AND THE FORMATION OF HABITABLE PLANETS ALL OF WHICH ARE GOALS STATED IN THE NASA ASTROBIOLOGY ROADMAP. THE CONFERENCE CHAIR IS MATTHEW PASEK AND THE VICE-CHAIR IS NICOLLE ZELLNER WHO WILL BE CHAIR IN 2020. THIS CONFERENCE MEETING IS PRECEDED BY THE GORDON RESEARCH SEMINAR WHICH BRINGS GRAD STUDENTS POSTDOCS AND YOUNG RESEARCHERS TO THE MEETING WHERE THEY CAN PRESENT AND DISCUSS WITH COLLEAGUES IN A LOW-STRESS ENVIRONMENT AND BUILD A COHORT PRIOR TO THE MAIN WEEK-LONG MEETING. THE GORDON SEMINAR ATTENDEES WILL ALSO SERVE AS DISCUSSION LEADERS AND A FEW WILL ALSO BE SELECTED AS PRESENTERS FOR A SPECIAL THURSDAY NIGHT SESSION CONNECTING THE TWO MEETINGS SO THAT YOUNG SCIENTISTS MAY JOIN AND DISCUSS FINDINGS WITH THEIR SENIOR PEERS. THE SEMINAR IS LED BY CHAIRS AARON ENGELHART AND BRUCE DAMER. THE SUBJECTS COVERED AT THIS CONFERENCE INCLUDE METEORITES AND THE ORIGIN OF LIFE PREBIOTIC ENVIRONMENTS PREBIOTIC ASSEMBLY PHOSPHORUS AND PREBIOTIC CHEMISTRY AND HABITABLE WORLDS AMONG OTHERS. THE MEETING PRESENTERS ARE A DIVERSE LOT WITH OVER A THIRD COMING FROM FOREIGN COUNTRIES AND WITH A RANGE OF SENIORITY AND FAMILIARITY WITH THE ASTROBIOLOGY FIELD. NOTABLY A MAJORITY OF THE PLANNED SPEAKERS ARE FEMALE A FIRST FOR THIS GORDON CONFERENCE. SUPPORT OF THIS CONFERENCE WILL BE USED FOR YOUNG SCIENTISTS TO ATTEND THE GRS AND GRC COVERING REGISTRATION AND TRAVEL WHEN POSSIBLE. CURRENTLY ELSI TEMPLETON AND LIFE JOURNAL HAVE OFFERED SUPPORT FOR THE CONFERENCE AND WE ANTICIPATE SUPPORTING ABOUT FIFTY TO SIXTY ATTENDEES AT LEAST PARTIALLY.

2007 AMYGDALA IN HEALTH & DISEASE GORDON RESEARCH CONFERENCE

THIS EXCITING CONFERENCE HAS MET SINCE 1982 TO DISCUSS HOW LIVING ORGANISMS CAN EMERGE SPONTANEOUSLY WITHIN A NON-LIVING UNIVERSE. THE BREADTH AND COMPLEXITY OF THE TOPIC STAND TO GAIN MUCH FROM AN INTERNATIONAL IN-PERSON MEETING THAT TRANSCENDS DISCIPLINARY BOUNDARIES IN ORDER TO CREATE FRESH PERSPECTIVES. PLANNING FOR 2016 USES THE PRESTIGIOUS GORDON CONFERENCE IDENTITY TO DELIVER SUCH A MEETING. IN PARTICULAR THE RESEARCH REQUIRED TO UNDERSTAND LIFE'S ORIGINS OCCURS AT A POINT WHERE MULTIPLE SCIENTIFIC DISCIPLINES MEET. CHEMISTS BIOLOGISTS PHYSICISTS GEOSCIENTISTS PLANETARY SCIENTISTS ASTRONOMERS METEORITICISTS MATHEMATICIANS AND COMPUTER SCIENTISTS ARE AMONG THOSE CONTRIBUTING TO PROGRESS. COMBINING THE FINDINGS OF EACH DISCIPLINE INTO A COMPOSITE NARRATIVE PRODUCES MULTIDISCIPLINARY SCIENCE. THE ORIGINS RESEARCH COMMUNITY HAS ALREADY COME FAR IN THIS ENDEAVOR. MORE CHALLENGING IS TO EXTEND THESE CONNECTIONS INTO TRUE INTERDISCIPLINARY WHEREIN THE INSIGHTS OF ONE RESEARCH COMMUNITY INFLUENCE THE INTERPRETATION OF DATA AND QUESTIONS BEING ASKED BY OTHERS. THE FORTHCOMING GORDON RESEARCH CONFERENCE WILL EXPLORE THIS TRANSITION FROM MULTIDISCIPLINARY TO INTERDISCIPLINARY. IT WILL VISIT THE TRADITIONAL ARRAY OF TOPICS FROM LUCA TO THE NONLIVING UNIVERSE. IT WILL EMPHASIZE HOWEVER SPEAKERS WHOSE WORK CROSSES TRADITIONAL DISCIPLINARY BOUNDARIES. IT WILL CREATE SPACES WHERE SCIENTISTS FROM DIFFERENT DISCIPLINES ARE CHALLENGED TO BUILD BRIDGES OF KNOWLEDGE BETWEEN THEIR RESPECTIVE AREAS OF EXPERTISE. THIS INSTANCE OF THE CONFERENCE ALSO PROVIDES NOVELTY BY REINSTATING A 2-DAY SEMINAR (THE GRS) PRECEDING THE GRC THAT IS RESTRICTED TO EARLY-CAREER SCIENTISTS. IT THEN LEVERAGES THIS SEMINAR BY CHALLENGING THE EARLY-CAREER SCIENTISTS TO DISCUSS AND CONSOLIDATE QUESTIONS TO BE BROUGHT FORWARD INTO THE MAIN CONFERENCE THROUGH SESSION HOSTS WITHIN THE GRC. BOTH THE GRS AND GRC PROGRAMMING LEVERAGE A SIGNIFICANT PRESENCE FROM DIVERSE NASA PROJECTS (ASTROBIOLOGY CAN TEAMS MIRS POSTDOCTORAL FELLOWSHIPS MISSIONS) WITHIN A MUCH BROADER CONTEXT OF THE NATIONAL AND INTERNATIONAL RESEARCH COMMUNITY. SPECIFIC RELEVANCE TO NASA AND ITS PROGRAMS IS FOUND LARGELY WITHIN THE 2008 ASTROBIOLOGY ROADMAP GOAL 3 (GOAL 3-UNDERSTAND HOW LIFE EMERGES FROM COSMIC AND PLANETARY PRECURSORS...) SPECIFIC CONFERENCE SESSIONS ALSO SPEAK TO ROADMAP GOALS 1 2 4 AND 7. BEYOND THIS SPECIFIC PRESENTATIONS SPEAK TO MISSION WORK (MOST NOTABLY THOSE CONCERNED WITH MARS EUROPA ASTEROIDS COMETS AND THE MOON).

2010 NEURAL DEVELOPMENT GORDON RESEARCH CONFERENCE

EXPANDING PARTICIPATION FOR WOMEN AND MINORITIES IN THE 2022 NEUROBIOLOGY OF COGNITION GORDON RESEARCH SEMINAR & CONFERENCE

2019 UNDERGRADUATE BIOLOGY EDUCATION RESEARCH GRC

2010 NEUROBIOLOGY OF COGNITION GORDON RESEARCH CONFERENCE

2009 EXCITATORY SYNAPSES AND BRAIN FUNCTION GORDON RESEARCH CONFERENCE

EYE MOVEMENTS: THE MOTOR SYSTEM THAT SEES THE WORLD

2022 SYSTEMS AGING GORDON RESEARCH CONFERENCE - PROJECT ABSTRACT THIS APPLICATION REQUESTS FUNDS TO SUPPORT THE INAUGURAL 2022 SYSTEMS AGING GORDON RESEARCH CONFERENCE (GRC), TO BE HELD AT GRAND SUMMIT HOTEL AT SUNDAY RIVER (NEWRY, MAINE, USA) ON MAY 29- JUNE 03, 2022. THE LAST SEVERAL YEARS HAVE SEEN AN EXPLOSIVE GROWTH OF RESEARCH ON QUANTITATIVE, OMICS AND WHOLE-ORGANISMAL APPROACHES TO AGING, LONGEVITY, AND AGE-RELATED DISEASES. THIS INCLUDES THE DEVELOPMENT OF RELIABLE BIOMARKERS OF AGING THAT FACILITATE HUMAN CLINICAL TRIALS OF LONGEVITY AND NEW INSIGHTS IN FUNDAMENTAL MECHANISMS OF AGING THAT ACT ON A SYSTEMIC LEVEL. THESE DEVELOPMENTS ARE DISTINCT BUT COMPLEMENTARY TO THE ADVANCES IN MECHANISTIC STUDIES, WHICH FORMS THE BASIS FOR ANOTHER GRC ON AGING (BIOLOGY OF AGING). EMERGING FROM SYSTEMIC, QUANTITATIVE, BIOMARKER APPROACHES IS A NEW UNDERSTANDING OF AGING, WHICH CAN BE TRACKED, MONITORED, MANIPULATED AND IN SOME CASES REVERSED. SYSTEMS AGING GRC IS EXPECTED TO BECOME THE PREMIER FORUM FOR DISCUSSIONS AT THE FOREFRONT OF THIS NEW FIELD THAT TRANSCENDS THE HISTORIC SEPARATION INTO BASIC BIOLOGY OF AGING AND THE TREATMENT OF AGE-RELATED DISEASES. THE THEME OF THE 2022 CONFERENCE WILL BE SYSTEMIC PROCESSES, OMICS APPROACHES AND BIOMARKERS IN AGING. TO LINK, CROSS-POLLINATE AND INTEGRATE INVESTIGATORS FROM DIVERSE AREAS, SESSIONS ARE ORGANIZED AROUND THE FOLLOWING THEMES: DELAYING AND REVERSING AGING, WHOLE ORGANISM APPROACHES AND REJUVENATION, GENOMICS OF AGING, EPIGENETIC BIOMARKERS OF AGING, CLINICAL AND MOLECULAR BIOMARKERS OF AGING, ARTIFICIAL INTELLIGENCE AND MACHINE LEARNING, AGING AS A SYSTEMIC PROCESS, COMPARATIVE GENOMICS OF AGING, AND FUNDAMENTAL BASES OF AGING. OUR ORGANIZATIONAL PRINCIPLES ARE TO DEVELOP: 1) A COMPREHENSIVE PROGRAM THAT FEATURES KEY ADVANCES IN THE FIELD; 2) AN ATMOSPHERE THAT FACILITATES DISCUSSION, CRITICAL ANALYSIS AND EXCHANGE OF IDEAS BETWEEN SCIENTISTS FROM DIVERSE FIELDS WORKING ON SYSTEMIC APPROACHES TO AGING; 3) A VENUE THAT PROMOTES INTERACTIONS AMONG ESTABLISHED INVESTIGATORS, JUNIOR COLLEAGUES, POSTDOCS AND STUDENTS; 4) A STRATEGY TO SUPPORT WOMEN, UNDERREPRESENTED MINORITIES AND JUNIOR INVESTIGATORS AS WELL AS FOSTER CAREER ADVANCEMENT OF INVESTIGATORS FROM DIVERSE BACKGROUNDS; AND 5) A CONFERENCE THAT WILL BECOME A HOME BASE TO PEOPLE WORKING IN THIS EMERGING FIELD.

2019 STRESS PROTEINS IN GROWTH, DEVELOPMENT, AND DISEASE GRC/GRS

2017 OXIDATIVE STRESS AND DISEASE GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR

2015 AGING, BIOLOGY OF GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR

2014 NEUROBIOLOGY OF BRAIN DISORDERS GORDON RESEARCH CONFERENCE & GORDON RESEARCH

2013 OXIDATIVE STRESS AND DISEASE GORDON RESEARCH CONFERENCE & SEMINAR

2013 AGING, BIOLOGY OF GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR

2011 CHRONOBIOLOGY GORDON RESEARCH CONFERENCE

2009 BIOLOGY OF AGING GORDON RESEARCH CONFERENCE

2021 AND 2023 ALCOHOL-INDUCED END ORGAN DISEASES GORDON RESEARCH CONFERENCE - ABSTRACT ALCOHOL MISUSE IS ONE OF THE WORLD'S LEADING PREVENTABLE HEALTH RISKS. ALCOHOL USE AND ABUSE IS A CAUSAL FACTOR IN OVER 60 DIFFERENT DISEASES AND INJURIES PUTTING AN ENORMOUS HEALTH AND ECONOMIC BURDEN ON SOCIETIES WORLDWIDE. THE MAJOR SHARE OF ALCOHOL-INDUCED MORBIDITY AND MORTALITY IS ATTRIBUTABLE TO ALCOHOL-INDUCED END ORGAN DISEASES, INCLUDING CANCER, ALCOHOLIC LIVER DISEASE, PANCREATITIS, OSTEOPOROSIS, DIABETES MELLITUS, HYPERTENSION, ISCHEMIC HEART DISEASE, ARRHYTHMIAS, STROKE, PNEUMONIA AND FETAL ALCOHOL SYNDROME. ALCOHOL USE DISORDERS ARE ON THE RISE IN ALL SEGMENTS OF SOCIETY AND THEY OFTEN SYNERGIZE WITH OTHER DISEASES THAT HAVE REACHED EPIDEMIC PROPORTIONS INCLUDING OBESITY, DIABETES, METABOLIC SYNDROME, DRUG ABUSE AND IMMUNOLOGICAL MALADIES. DESPITE THE SIGNIFICANT ADVANCES OF THE FIELD OVER THE LAST TWO DECADES, THE UNDERLYING DISEASE ETIOLOGY IS POORLY UNDERSTOOD AND THERE IS AN URGENT NEED TO GAIN NEW KNOWLEDGE OF THE MOLECULAR UNDERPINNINGS OF ALCOHOL-INDUCED END ORGAN DISEASES TO ACCELERATE DIAGNOSIS, PREVENTION, AND TREATMENT. IN THIS R13 APPLICATION, WE ARE SEEKING SUPPORT FOR THE GORDON RESEARCH CONFERENCES (GRC) ALCOHOL-INDUCED END ORGAN DISEASES 2021 AND 2023. THIS IS A RELATIVELY NEW GRC, WHICH WAS INITIATED THREE YEARS AGO HELD EXTREMELY SUCCESSFUL MEETINGS IN 2017 AND 2019. THE OPEN FORMAT OF GRC MODEL INCLUDES SHARING SIGNIFICANT UNPUBLISHED WORK AND PROVIDES AMPLE OPPORTUNITIES FOR IN-DEPTH DISCUSSIONS WITH PEERS, NEW COLLEAGUES AND THE FUTURE GENERATION OF ALCOHOL RESEARCHERS; THIS CONFERENCE MODEL IS IDEALLY SUITED FOR PROPELLING THE FIELD TO NEW HEIGHTS. THE OVERALL GOAL OF THE ALCOHOL-INDUCED END ORGAN DISEASES MEETINGS ARE TO FOSTER OPEN DISCUSSION OF RESEARCH DEVELOPMENTS, ESTABLISH NEW SCIENTIFIC COLLABORATIONS, AND PROPEL THE NEXT GENERATION OF SCIENTIFIC ADVANCES. THIS GRC FILLS A CRITICAL NEED IN THE FIELD FOR A CONTINUING MEETING THAT PRESENTS KEY RECENT FINDINGS ON ALCOHOL-INDUCED END ORGAN INJURY AND REPAIR IN A UNIQUE FORMAT THAT ENSURES TIME FOR IN-DEPTH DISCUSSIONS, FORMULATION OF NEW APPROACHES AND INITIATION OF NEW COLLABORATIONS. THIS CONFERENCE WILL 1) PROVIDE A FORUM THAT PROMOTES OPEN DISCUSSION OF CUTTING EDGE RESEARCH AT THE FOREFRONT OF ALCOHOL-INDUCED TISSUE INJURY, 2) FOSTER THE DEVELOPMENT OF THE NEXT GENERATION OF ALCOHOL AND TISSUE INJURY INVESTIGATORS, 3) PROMOTE INTERACTION BETWEEN YOUNG AND SENIOR INVESTIGATORS, 4) FACILITATE THE EXCHANGE OF IDEAS THAT WILL SHAPE THE FUTURE DIRECTIONS OF THE ALCOHOL AND TISSUE INJURY COMMUNITY AND 5) INTRODUCE BREAKTHROUGH TECHNIQUES THAT FACILITATE THE UNDERSTANDING OF MECHANISMS DRIVING ALCOHOL-INDUCED TISSUE INJURIES. WE ENVISION THE GRC ON “ALCOHOL INDUCED END ORGAN DISEASES” WILL SIGNIFICANTLY ADVANCE CURRENT UNDERSTANDING OF THE UNDERLYING MECHANISMS OF END ORGAN INJURIES AND STIMULATE DEVELOPMENT OF EFFECTIVE THERAPEUTIC STRATEGIES FOR THE DIAGNOSIS, PREVENTION AND TREATMENT OF ALCOHOL USE DISORDERS.

2014 NEUROBIOLOGY OF COGNITION GORDON RESEARCH CONFERENCE

CONFERENCE: 2023 ENVIRONMENTAL NANOTECHNOLOGY GRC AND GRS NANOTECHNOLOGY FOR A MORE SUSTAINABLE WORLD -NANOMATERIALS AND RELATED TECHNOLOGIES ARE BEING WIDELY DEVELOPED FOR USE IN A NUMBER OF ADVANCED APPLICATIONS INCLUDING COATINGS, ANTIMICROBIALS, COMPONENTS IN SUNSCREENS, ELECTRONICS, CATALYSTS, AND OTHER PRODUCTS AND PROCESSES. IN PARTICULAR, NANOSCALE MATERIALS AND TECHNOLOGIES HAVE SIGNIFICANT POTENTIAL FOR ADDRESSING TOUGH ENVIRONMENTAL CHALLENGES FROM CLEAN WATER TO RENEWABLE ENERGY TO CLIMATE CHANGE, AND BEYOND. THE 6TH GORDON RESEARCH CONFERENCE ON ENVIRONMENTAL NANOTECHNOLOGY WILL FOCUS ON ADVANCING UNDERSTANDING OF SUCH MATERIALS AND PROCESSES TOWARDS A MORE SUSTAINABLE WORLD, CONSIDERING BOTH APPLICATIONS AND IMPLICATIONS. THE ENVIRONMENTAL NANOTECHNOLOGY GORDON RESEARCH CONFERENCE IS ONE OF THE MOST INTERACTIVE CONFERENCES ON THIS TOPIC AND HAS BEEN A PLATFORM FOR THE GENERATION OF INNOVATIVE IDEAS THAT GO ON TO HEAVILY INFLUENCE THE FIELD. PARTICIPANTS INCLUDE A LARGE BREADTH OF RESEARCHERS FROM ALL BACKGROUNDS AND CAREER STAGES, INCLUDING GRADUATE STUDENTS, PROFESSORS, INDUSTRY AND GOVERNMENT REPRESENTATIVES, AND INTERNATIONAL SCIENTISTS, WHO ENCOURAGE DISCUSSION ABOUT THE LATEST DEVELOPMENTS IN THE FIELD. THE OPEN EXCHANGE OF IDEAS AND THE COLLABORATIONS AND TOPICAL DISCUSSIONS THAT ORIGINATE AT THIS CONFERENCE ARE FUNDAMENTAL IN FURTHER ADVANCING THE FIELD. LASTLY, THE SCHEDULED ACTIVITIES OF THE GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SCHOOL PROVIDE UNIQUE OPPORTUNITIES FOR EARLY-CAREER SCIENTISTS BY INTEGRATING THESE NEW SCIENTISTS INTO AN OPEN AND WELCOMING ENVIRONMENT TO DISCUSS THEIR CURRENT RESEARCH AND BUILD INFORMAL NETWORKS WITH THEIR PEERS THAT CAN LEAD TO A LIFETIME OF COLLABORATION AND SCIENTIFIC ACHIEVEMENT. THE ORGANIZATION AND FOCUS OF THE SIXTH ENVIRONMENTAL NANOTECHNOLOGY GORDON RESEARCH CONFERENCE IS DESIGNED TO BE AT THE LEADING EDGE OF ENVIRONMENTAL NANOTECHNOLOGY APPLICATIONS AND IMPLICATIONS. THE OBJECTIVES OF THE ENVIRONMENTAL NANOTECHNOLOGY GORDON CONFERENCE ARE TO 1) PROVIDE A FORUM FOR THE GENERATION OF IDEAS FOR USING NANOTECHNOLOGY TO BENEFIT THE ENVIRONMENT AND SOCIETY THROUGH ITS ROLE IN TECHNOLOGY DEVELOPMENT AND 2) TO GENERATE IDEAS AND RESEARCH PROGRAMS TOWARDS PREVENTION OF POTENTIAL ENVIRONMENTAL HARM THAT MAY COME FROM THE DEVELOPMENT AND USE OF THIS TECHNOLOGY. DISCUSSIONS REVOLVE AROUND RESEARCH THAT WILL ADVANCE FUNDAMENTAL UNDERSTANDINGS OF THE INTERACTIONS OF NANOMATERIALS WITH BIOLOGICAL AND ENVIRONMENTAL MEDIA. THE CONFERENCE AIMS TO DISCUSS MATERIALS THAT ARE IN CURRENT USE AS WELL AS NEW ONE- TO THREE-DIMENSIONAL NANOSTRUCTURES, HETEROGENEOUS NANO-BIO HYBRID ASSEMBLIES, AND ACTIVE NANOPARTICLES THAT MAY BE DEVELOPED AND USED IN THE FUTURE. SPECIFIC CONFERENCE TOPICS INCLUDE NOVEL NANOMATERIALS AND PROCESSES FOR WATER TREATMENT, CLIMATE CHANGE, AGRICULTURE, CIRCULAR ECONOMIES, AND SENSING, AMONG OTHERS. THE INTELLECTUAL MERIT OF THE GORDON RESEARCH CONFERENCE ON ENVIRONMENTAL NANOTECHNOLOGY IS FOUNDED IN THE CREATION AND NUCLEATION OF IDEAS TOWARDS DEVELOPMENT OF RELATED ENGINEERED NANOMATERIAL-BASED TECHNOLOGIES WITH A FOUNDATION IN ENVIRONMENTALLY SUSTAINABLE GOALS AND IDEALS. THERE IS CONSIDERABLE INTELLECTUAL MERIT IN THE OPEN EXCHANGE OF IDEAS ON THESE CRITICAL GLOBAL TOPICS, WHICH IS A GORDON RESEARCH CONFERENCE HALLMARK. THIS CONFERENCE WILL HIGHLIGHT ANALYTICAL METHODS AND EXPERIMENTAL APPROACHES THAT BALANCE THE BENEFICIAL ASPECTS OF NANOTECHNOLOGY AGAINST THEIR POTENTIAL ADVERSE RISKS TO HUMAN HEALTH AND THE ENVIRONMENT. COLLABORATIONS AND IDEAS THAT ORIGINATE AT THIS CONFERENCE, DUE TO ITS DIVERSITY OF PARTICIPATING FIELDS AND ATTENDEES, IS FUNDAMENTAL IN ADVANCING THE FIELD OF EMERGING NANOSCALE MATERIALS AND PROCESSES, WHICH INCLUDES RELATED NANOSCALE INTERACTIONS OF ALL TYPES. BROADER IMPACTS OF THIS CONFERENCE ARE MANY, AS IDEAS DISCUSSED AT THIS MEETING WILL HELP SHAPE SUSTAINABLE DEVELOPMENT OF RELATED TECHNOLOGIES IN ADDITION TO KEY SOCIETAL ADVANCES INCLUDING SENSORS FOR CONTAMINANTS, WATER CLEANUP AND TREATMENT, CLIMATE CHANGE, AND INNOVATIONS FOR PRESENTING NANOMATERIAL SCIENCE TO THE PUBLIC. THE ACTIVITIES OF THE GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SCHOOL; ALSO, PRESENT UNIQUE OPPORTUNITIES FOR DIVERSE AND EARLY-CAREER SCIENTISTS BY INTEGRATING THESE NEW SCIENTISTS INTO A NEW, WELCOMING COLLABORATIVE PEER NETWORK. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

2022 GORDON RESEARCH CONFERENCE ON MULTIFUNCTIONAL MATERIALS & STRUCTURES: IMPARTING INTELLIGENCE IN AND THROUGH SELF-LEARNING MATERIALS & STRUCTURES; VENTURA, CA; 23-28 JAN 2022

**AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** THIS APPLICATION SEEKS PARTIAL SUPPORT FOR THE GORDON RESEARCH CONFERENCE (GRC) AND GORDON RESEARCH SEMINAR (GRS) ON QUANTITATIVE GENETICS AND GENOMICS TO BE HELD IN RENAISSANCE TUSCANI II CIOCCO, LUCA, ITALY ON FEBRUARY 16-21, 2025.THE GRC AND GRS AIMS TO (1) PROMOTE COMMUNICATION BETWEEN SCIENTISTS IN THE FIELD OF QUANTITATIVE GENETICS AND GENOMICS, (2) FOSTER NEW COLLABORATIONS AMONG SCIENTISTS WITH DIFFERENT BACKGROUNDS, AND (3) BUILD A COMMUNITY FOR EARLY CAREER RESEARCHERS (ECR). WE WILL ACHIEVE THESE OBJECTIVES BY OFFERING AN OUTSTANDING AND DIVERSE OUTLINE OF SPEAKERS AND THROUGH A CONFERENCE FORMAT THAT IS DESIGN TO PROMOTE INTERACTIONS AMONG SCIENTISTS. THE MAIN THEME FOR THE 2025 GRC WILL BE THE INTERPLAY BETWEEN GENETICS AND THE ENVIRONMENT.

THIS FOURTH GORDON RESEARCH CONFERENCE (GRC) ON NANOTECHNOLOGY FOR AGRICULTURE AND FOOD SYSTEMS, SCHEDULED FOR JUNE, 2024, WILL PROVIDE AN INTERACTIVE, ENGAGING, AND CONFIDENTIAL FORUM FOR EXPERTS FROM ACADEMIA, INDUSTRY, AND GOVERNMENT AGENCIES TO DISCUSS CUTTING EDGE, UNPUBLISHED RESEARCH, AND TO DEFINE FUTURE DIRECTIONS OF THE FIELD. IN APPRECIATION OF THE MULTI-DISCIPLINARY NATURE OF THIS GROWING FIELD, A DIVERSE RANGE OF INVITED SPEAKERS AND DISCUSSION LEADERS FROM 12 COUNTRIES WILL PRESENT A COMPREHENSIVE VISION OF CRITICAL AND EMERGING NANOTECHNOLOGY RESEARCH ADVANCES ACROSS THE FIELD OF AGRICULTURAL AND FOOD SCIENCE. FOCAL AREAS INCLUDE: NANOMATERIALS, NANOMATERIAL-BASED SYSTEMS ON ALL LEVELS (MOLECULAR TO GLOBAL SCALE), THEIR INTEGRATION THROUGH BIG DATA AND ARTIFICIAL INTELLIGENCE, SENSORS, RISK ASSESSMENT, AND COMMERCIAL TRANSLATION INTO AGRICULTURAL AND FOOD PRODUCTION SYSTEMS. THE THEME OF IMPACTFUL RESEARCH AND APPLICATIONS FOR SUSTAINABLE FOOD PRODUCTION WILL PROVIDE COHESION AND A UNIQUE PERSPECTIVE OF THE 2024 GRC. WITH GROWING AGRICULTURAL DEMANDS ON DIMINISHING ARABLE LANDS, AGRICULTURAL OUTPUT AND FOOD PRODUCTION WILL REQUIRE INNOVATIVE TECHNOLOGIES AND A COLLECTIVE VOICE OF SCIENTISTS, ENGINEERS, AND STAKEHOLDERS TO ADDRESS GLOBAL NEEDS. NANOTECHNOLOGY HAS THE POTENTIAL TO REVOLUTIONIZE GLOBAL AGRICULTURAL AND FOOD SYSTEMS IN NUMEROUS WAYS, AND THE GRC HELPS BUILD A DIVERSE COMMUNITY COMMITTED TO ADVANCING WORK IN THE AREA OF NANOTECHNOLOGY FOR AGRICULTURE AND FOOD SYSTEMS, LEADING TO NOVEL IDEAS AND APPROACHES TO CREATE A SUSTAINABLE FUTURE.THE OBJECTIVES OF THIS GRC ARE: 1) BRING TOGETHER EXPERTS, EMERGING INVESTIGATORS AND STAKEHOLDERS TO DISCUSS NANOTECHNOLOGY ADVANCES, DIRECTIONS, AND NEEDS IN FOOD AND AGRICULTURE; 2) IDENTIFY CUTTING-EDGE RESEARCH AND EMERGING OPPORTUNITIES TO ADDRESS GLOBAL CHALLENGES OF FOOD SECURITY, ENVIRONMENTAL SUSTAINABILITY, FOOD SAFETY, AND AGRICULTURAL PRODUCTIVITY, AND 3) EMBOLDEN THE KNOWLEDGE THAT NANO IN FOOD &AMP; AGRICULTURE REPRESENTS A SINGLE UNIFYING CONCEPT, RATHER THAN TWO DISTINCT FIELDS.

2020 NANOSCALE SCIENCE AND ENGINEERING FOR AGRICULTURE AND FOOD SYSTEMS GORDON RESEARCH CONFERENCE

2018 GORDON RESEARCH CONFERENCE ON NANOTECHNOLOGY APPLIED TO AGRICULTURE AND FOOD

2020 CLIMATE ENGINEERING GRC AND GRS: NEWRY, ME - SUMMER 2020

CONFERENCE: ENVIRONMENTAL NANOTECHNOLOGY: GORDON RESEARCH CENTER AND GORDON RESEARCH SEMINAR, JUNE 20-21, 2015, MOUNT SNOW RESORT, WEST DOVER, VERMO

UNDERGRADUATE BIOLOGY EDUCATION RESEARCH: INVESTIGATION AND IMPLEMENTATION CONFERENCE, JULY 12-17, 2015 AT BATES COLLEGE IN MAINE

CONFERENCE: SCIENCE AND TECHNOLOGY POLICY: SYSTEMS APPROACHES TO RESEARCH AND PRACTICE GRC/GRS

CONFERENCE: 2013 ENVIRONMENTAL NANOTECHNOLOGY GRC, STOVE, VT, JUNE 2 - 7, 2013

2022 NEUROBIOLOGY OF BRAIN DISORDERS GRC AND GRS - PROJECT SUMMARY/ABSTRACT THE SPECIFIC AIMS OF THE 2022 NEUROBIOLOGY OF BRAIN DISORDERS GORDON RESEARCH CONFERENCE (GRC) AND GORDON RESEARCH SEMINAR (GRS) ARE TO PROMOTE DIALOGUE AMONG ESTABLISHED AND EMERGING LEADERS IN NEURODEGENERATIVE DISEASE FOCUSING ON ALZHEIMER'S DISEASE AND RELATED DEMENTIAS. THE CO-CHAIRS, DRS. ALISON GOATE AND LEONARD PETRUCELLI, IN CONSULTATION WITH PAST CHAIRS, AND THE 2022 VICE CHAIRS (DRS. KAREN DUFF AND CHRISTOPHER SHAW) HAVE PLANNED NINE ORAL SESSIONS: SESSION 1 - KEYNOTE ADDRESS ON THE DEVELOPMENT OF NOVEL BLOOD-BASED BIOMARKERS FOR NEURODEGENERATIVE DISEASE, SESSION 2 - GENETIC AND GENOMIC APPROACHES TO NEURODEGENERATIVE DISEASE, SESSION 3 - EPIGENETICS OF NEURODEGENERATIVE DISEASE, SESSION 4 - FRONTOTEMPORAL DEMENTIA AND ALS: MECHANISMS, SESSION 5 - PARKINSON'S DISEASE: MECHANISMS, SESSION 6 - ALZHEIMER'S DISEASE: MECHANISMS, SESSION 7 - TAUOPATHIES: MECHANISM, & BIOMARKERS, SESSION 8 - BIOMARKERS: DIAGNOSIS AND THERANOSTICS, AND SESSION 9 - THERAPEUTIC APPROACHES. ALL INVITED SPEAKERS/DISCUSSANTS HAVE CONFIRMED THEIR PARTICIPATION, AND GENDER AND DIVERSITY-RELATED ISSUES ARE ADDRESSED AS 17 OF 33 ACCEPTED SPEAKERS/DISCUSSANTS ARE WOMEN (51.5%), 5 ARE NON-EUROPEAN (15%) AND 5 (15%) ARE YOUNG INVESTIGATORS. 11 OF THE INVITED SPEAKERS ARE INTERNATIONAL (33%). THE GRC WILL BE PRECEDED BY A GRS TO FACILITATE PRESENTATION AND DISCUSSION OF FRONTIER RESEARCH BY TRAINEES. AS THE CHAIRS AND CO-CHAIRS PLACE THE HIGHEST PRIORITY ON PARTICIPATION BY TRAINEES AND EARLY CAREER INDIVIDUALS, SHORT TALKS WILL BE SELECTED FROM SUBMITTED ABSTRACTS TO COMPLEMENT INVITED SPEAKERS. WE WILL MAKE EVERY EFFORT TO INCREASE PARTICIPATION OF UNDER-REPRESENTED MINORITIES AMONG CONFERENCE PARTICIPANTS AND SPEAKERS. CONFERENCE PARTICIPANTS WILL INTERACT INFORMALLY IN A COLLEGIAL ATMOSPHERE AND HAVE AMPLE FREE TIME, PROVIDING IDEAL SETTINGS FOR PARTICIPANTS TO BRAINSTORM AND ESTABLISH INTERDISCIPLINARY COLLABORATIONS. THE SIGNIFICANCE OF THIS GRC IS TO PROVIDE A UNIQUE FORUM FOR THE INTERNATIONAL COMMUNITY WORKING ON THE NEUROBIOLOGY OF BRAIN DISORDERS INCLUDING ALZHEIMER'S DISEASE AND RELATED DEMENTIAS TO DISCUSS THE LATEST ADVANCES AND THE FUTURE CHALLENGES IN THE FIELD OF NEURODEGENERATION AND AGING RELATED BRAIN DISORDERS. THE RELEVANCE OF THIS APPLICATION TO PUBLIC HEALTH IS THAT THE DISCUSSIONS WILL DEFINE THE MOST IMPORTANT QUESTIONS IN THE FIELD OF NEURODEGENERATIVE DISEASES INCLUDING ALZHEIMER'S DISEASE AND RELATED DEMENTIAS SPANNING BASIC BIOLOGY AND DISEASE MECHANISMS AND AID THE DEVELOPMENT OF NOVEL THERAPEUTIC STRATEGIES. THE LONG-TERM GOAL OF THIS GRC IS TO PROVIDE A CONSISTENT PLATFORM FOR THIS COMMUNITY TO MEET EVERY TWO YEARS TO DISSEMINATE THE MOST RECENT DISCOVERIES AND FORMULATE THE MOST IMPORTANT QUESTIONS CONCERNING THE CURRENT STATE OF THE ART RESEARCH ON AGE RELATED NEURODEGENERATIVE DISEASES.

2017 CATECHOLAMINES GORDON RESEARCH CONFERENCE & GORDON RESEARCH SEMINAR

2018 NEUROBIOLOGY OF BRAIN DISORDERS GRC AND GRS

CONFERENCE: 2023 CATCHMENT SCIENCE: INTERACTIONS OF HYDROLOGY, BIOLOGY AND GEOCHEMISTRY GRC AND GRS CHALLENGES AND UNCERTAINTY IN PREDICTING CATCHMENT RESPONSES TO STRESS -STRESS IMPACTS OUR NATURAL WORLD IN COMPLEX WAYS. UNDERSTANDING HOW THOSE COMPLEXITIES MANIFEST IN WATER, NUTRIENT, AND POLLUTANT MOVEMENT THROUGH THE NATURAL AND HUMAN LANDSCAPE REQUIRES BRINGING TOGETHER SCIENTISTS WITH EXPERTISE IN A RANGE OF TOPICS. THIS INTERDISCIPLINARY APPROACH HAS BEEN REFERRED TO AS CATCHMENT SCIENCE, WHICH DELIBERATELY SEEKS TO INCLUDE NOT ONLY HYDROLOGISTS, BUT ALSO SOIL SCIENTISTS, ECOLOGISTS, CHEMISTS AND OTHERS. TOGETHER CATCHMENT SCIENTISTS CAN TACKLE COMPLEX ENVIRONMENTAL PROBLEMS AT A SCALE THAT LEVERAGES USEFUL SYSTEM BOUNDARIES. THIS AWARD SUPPORTS EARLY-CAREER AND DIVERSE RESEARCHERS TO ATTEND A GORDON RESEARCH CONFERENCE IN CATCHMENT SCIENCE IN JUNE 2023. THIS CONFERENCE AND ITS ASSOCIATED SEMINAR FOR GRADUATE STUDENTS AND POSTDOCTORAL RESEARCHERS WILL FOSTER THE PROFESSIONAL DEVELOPMENT OF THE NEXT GENERATION OF RESEARCHERS IN CATCHMENT SCIENCE AND THE DEVELOPMENT OF A CORE FOUNDATION OF RESEARCH TO TACKLE THE STRESSORS OF TODAY AND TOMORROW. THE CONFIRMED PROGRAM INCLUDES A DIVERSE GROUP OF SCIENTISTS FROM DIFFERENT CAREER STAGES AND BACKGROUNDS, INCLUDING MULTI-SCALE MODELING, PHARMACEUTICALS AND EMERGING CONTAMINANTS, MICROPLASTICS, DROUGHT, FIRE, AND EMERGING TOOLS TO INTEGRATE DATA FROM THESE OVERLAPPING STRESSORS. OVER THE COMING MONTHS, THIS CONFERENCE WILL PROVIDE DIRECTION TO RESEARCH ON ENVIRONMENTAL STRESSORS AND HOW TO DISENTANGLE AND PREDICT THEIR LIKELY EFFECTS. OVER THE COMING YEARS, THIS CONFERENCE WILL SUPPORT A MORE DIVERSE AND CONNECTED INTERNATIONAL COMMUNITY OF CATCHMENT SCIENTISTS AND NEW TOOLS AND CONCEPTUAL MODELS IN CATCHMENT SCIENCE. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

CONFERENCE: 2026 GEOLOGIC HYDROGEN GORDON CONFERENCE: GENERATION, STIMULATION, MIGRATION, ACCUMULATION, EXPLORATION, AND ECONOMIC-ENVIRONMENTAL CONSIDERATIONS OF GEOLOGIC HYDROGEN -THIS AWARD SUPPORTS THE 2026 GORDON RESEARCH CONFERENCE ON GEOLOGIC HYDROGEN, AN EMERGING FIELD EXPLORING NATURALLY OCCURRING HYDROGEN IN EARTH?S SUBSURFACE AND WAYS TO ENHANCE ITS PRODUCTION. HYDROGEN IS ESSENTIAL FOR PRODUCING COMMODITY CHEMICALS AND MEETING ENERGY NEEDS. AS AN ALTERNATIVE TO MANUFACTURING HYDROGEN, WHICH REQUIRES ENERGY-INTENSIVE PROCESSES, PATHWAYS TO HARNESS THE SUBSURFACE ENVIRONMENT TO PRODUCE GEOLOGIC HYDROGEN ARE EMERGING AS ECONOMICALLY VIABLE AND ENVIRONMENTALLY BENIGN SOLUTIONS. EARLY DISCOVERIES AND RAPIDLY GROWING INDUSTRIAL INTEREST SUGGEST THAT GEOLOGIC HYDROGEN COULD BECOME A VAST SOURCE OF AFFORDABLE ENERGY, BUT MAJOR UNCERTAINTIES REMAIN REGARDING THE MECHANISMS UNDERLYING ITS FORMATION, TRANSPORT BEHAVIOR AND ACCUMULATION, AND APPROACHES TO EVALUATE ECONOMIC AND ENVIRONMENTAL IMPACTS. CONSEQUENTLY, THE AIM OF THIS CONFERENCE IS TO ADDRESS THESE CHALLENGES AND ACCELERATE THE CREATION OF FUNDAMENTAL SCIENTIFIC INSIGHTS AND INNOVATIVE TECHNOLOGICAL DEVELOPMENT PATHWAYS FOR UNLOCKING THE POTENTIAL OF GEOLOGIC HYDROGEN AS A RELIABLE AND AFFORDABLE ENERGY SOURCE. THIS CONFERENCE CONVENES LEADING EXPERTS WITH THE INTENT TO ADVANCE THE FIELD OF GEOLOGIC HYDROGEN AND TRAIN THE NEXT GENERATION OF SCIENTISTS AND ENGINEERS. THE PROJECT WILL BROADEN PARTICIPATION BY PRIORITIZING STUDENTS AND EARLY-CAREER RESEARCHERS, STRENGTHENING THE U.S. WORKFORCE, AND FOSTERING CROSS-DISCIPLINARY PARTNERSHIPS THAT CAN INFORM RESEARCH, INNOVATION, AND DECISION MAKING. THE 2026 GORDON RESEARCH CONFERENCE ON GEOLOGIC HYDROGEN WILL FEATURE DISCUSSION-CENTERED SESSIONS ACROSS THE FULL GEOLOGIC HYDROGEN SYSTEM. THE TECHNICAL PROGRAM COVERS NINE SESSIONS INCLUDING HYDROGEN AS A POTENTIAL PRIMARY ENERGY SOURCE; HYDROGEN GEOBIOCHEMISTRY; SOURCE ROCKS; MIGRATION AND ACCUMULATION MECHANISMS; MONITORING METHODS AND DETECTION; EXPLORATION; EXTRACTION; STIMULATED GEOLOGIC HYDROGEN PRODUCTION, AS WELL AS CRITICAL CONSIDERATIONS OF SAFETY, ENVIRONMENT, ECONOMICS, AND ECOSYSTEM IMPACTS. THE CONFERENCE IS DESIGNED TO SYNTHESIZE INSIGHTS FROM WIDE-RANGING TECHNOLOGY ROADMAP EFFORTS AND RECENT U.S. INVESTMENTS IN STIMULATED GEOLOGIC HYDROGEN PRODUCTION, WHILE MAINTAINING THE GORDON RESEARCH CONFERENCE STANDARD OF PRESENTING CUTTING-EDGE RESULTS. POSTER AND NETWORKING SESSIONS WILL FURTHER PROMOTE KNOWLEDGE EXCHANGE. A CAREER DEVELOPMENT SESSION AND A MENTOR-MENTEE PROGRAM LED BY THE ASSOCIATION OF GEOLOGICAL HYDROGEN WILL FOSTER WORKFORCE DEVELOPMENT AND CONTRIBUTE TO BUILDING A DURABLE GEOLOGIC HYDROGEN COMMUNITY. THESE EFFORTS ALIGN WITH NSF PRIORITIES IN EMPOWERING STEM TALENT TO FULLY PARTICIPATE IN THE CRITICAL SCIENCE AND ENGINEERING NEEDS, BENEFITING SOCIETY BY TRANSLATING KNOWLEDGE INTO SOLUTIONS, AND EXPANDING AND STRENGTHENING THE SPEED AND SCALE OF EMERGING RESEARCH AND COMMUNITIES. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

CONFERENCE: 2025 INTERIOR OF THE EARTH GORDON RESEARCH CONFERENCE AND SEMINAR -THIS PROPOSAL WILL SUPPORT THE PARTICIPATION OF EARLY CAREER SCIENTISTS IN THE JUNE 2025 INTERIOR OF THE EARTH GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR. THESE MEETINGS WILL FOCUS ON THE IMPACTS OF VOLATILES, IN PARTICULAR WATER AND CARBON, ON PROCESSES IN THE EARTH?S INTERIOR. THESE IMPACTS INCLUDE THE SOFTENING AND MELTING OF MANTLE ROCKS, WITH CONSEQUENCES ON TECTONIC PLATES AND THE CIRCULATION OF MANTLE MATERIAL, AND HOW THE PROPERTIES OF EARTH?S INTERIOR HAVE EVOLVED OVER TIME. THESE MEETINGS WILL EXAMINE HOW VOLATILES CYCLE BETWEEN THE EARTH?S INTERIOR TO ITS ATMOSPHERE, AND THE WATER AND ICE RESERVOIRS AT ITS SURFACE, INCLUDING PROCESSES SUCH AS VOLCANISM AND EROSION AND WEATHERING. ANOTHER TOPIC WILL BE HOW THE STRENGTH OF MANTLE ROCKS AFFECTS SOLID EARTH DEFORMATION IN RESPONSE TO THE CHANGING MASSES OF ICE SHEETS, WHICH IMPACTS PREDICTIONS OF SEA-LEVEL CHANGE. THIS FUNDING WILL ENABLE EARLY CAREER SCIENTISTS TO LEARN FROM AND CONTRIBUTE TO THE PRESENTATIONS AND DISCUSSIONS AT THESE MEETINGS, AND TO BUILD THEIR RESEARCH NETWORKS. BY ENGAGING NEW RESEARCHERS IN THE COMMUNITY THAT STUDIES THE EARTH?S INTERIOR, THIS PROPOSAL WOULD CONTRIBUTE TO WORKFORCE DEVELOPMENT AND PROMOTE PARTICIPATION IN RESEARCH DIRECTIONS SUPPORTED BY THE NSF DIVISION OF EARTH SCIENCES. THIS PROPOSAL WILL PROVIDE FUNDING FOR THE REGISTRATION FEES OF EARLY CAREER SCIENTISTS FOR THE 2025 INTERIOR OF THE EARTH GORDON RESEARCH CONFERENCE (GRC) AND GORDON RESEARCH SEMINAR (GRS). THE GRS, DESIGNED FOR EARLY CAREER SCIENTISTS, IS SCHEDULED FOR JUNE 21-22, 2025, AND THE GRC, OPEN TO RESEARCHERS AT ALL CAREER LEVELS, WILL TAKE PLACE FROM JUNE 22-27, 2025. THESE MEETINGS WILL BE HELD AT MOUNT HOLYOKE COLLEGE IN SOUTH HADLEY, MA. THE THEME OF THE 2025 INTERIOR OF THE EARTH GRC IS VOLATILES, MELT AND VISCOSITY: CONSEQUENCES FOR MANTLE EVOLUTION AND CLIMATE SYSTEM INTERACTION. THE MEETING WILL EXPLORE THE CUTTING-EDGE OF KNOWLEDGE REGARDING: THE DISTRIBUTIONS OF VOLATILES AND MELT IN THE MANTLE; THE NATURE OF MANTLE VISCOSITY, INCLUDING WHETHER IT IS INTRINSICALLY FREQUENCY-DEPENDENT OR SIMPLY SPATIALLY VARIABLE; HOW VOLATILES AND PARTIAL MELT FEED BACK INTO VISCOSITY; THE CYCLING OF VOLATILES IN THE MANTLE, INCLUDING SUBDUCTION ZONE PROCESSES; AND HOW METASOMATISM ALTERS AND POTENTIALLY STORES VOLATILES IN THE OCEANIC AND CONTINENTAL LITHOSPHERE. THE MEETING WILL ALSO EXAMINE THE PROCESSES THAT DOMINATE THE CYCLING OF VOLATILES BETWEEN THE EARTH?S INTERIOR AND ITS CLIMATE SYSTEM, INCLUDING ITS ATMOSPHERE, OCEANS AND ICE SHEETS. KEY TOPICS INCLUDE: THE IMPACT OF VOLATILES ON CRUSTAL MAGMA STORAGE AND VOLCANIC ERUPTIONS, BOTH ON EARTH AND ON OTHER PLANETARY BODIES; THE INTERPLAY OF MAGMATISM AND SURFACE EROSION IN REGULATING ATMOSPHERIC CARBON IN THE RECENT PLATE TECTONIC REGIME; AND THE POTENTIAL ROLE OF MANTLE OVERTURN IN ATMOSPHERIC EVOLUTION BILLIONS OF YEARS AGO. ANOTHER FOCUS WILL BE THE ROLE OF MANTLE VISCOSITY IN DETERMINING HOW THE SOLID EARTH RESPONDS TO CHANGING MASS LOADS SUCH AS ICE SHEETS AND SEA-LEVEL. THE 2025 INTERIOR OF THE EARTH GRC WILL EXPLORE THESE FASCINATING AND INTERWOVEN PROCESSES BY INTEGRATING PERSPECTIVES INCLUDING GEOCHEMISTRY, PETROLOGY, GEODYNAMICS, SEISMOLOGY, GEODESY, MAGNETOTELLURICS, ROCK DEFORMATION, MINERAL PHYSICS, PALEOMAGNETISM, AND GEOLOGY. THE MEETING WILL INCLUDE MORNING AND EVENING SESSIONS WITH TALKS AND DISCUSSION, ENGAGING POSTER SESSIONS, AND FREE AFTERNOONS TO PROMOTE INTERACTION AMONG PARTICIPANTS. THE THEME OF THE 2025 INTERIOR OF THE EARTH GRS IS COUPLED SURFACE-INTERIOR INTERACTIONS: THE ROLE OF VOLATILES IN SUBDUCTION AND ERUPTION PROCESSES. THE GRS WILL INCLUDE A KEYNOTE TALK, TALKS AND POSTERS BASED ON SUBMITTED ABSTRACTS, AND A PANEL ON SCIENCE COMMUNICATION METHODS AND CAREERS. STUDENTS AND POST-DOCS ATTENDING THE GRS WILL BE ENCOURAGED TO PARTICIPATE IN THE GRC. A KEY BROADER IMPACT OF THESE MEETINGS WILL BE TO ENGAGE AND SUPPORT EARLY CAREER SCIENTISTS IN STUDY OF THE EARTH?S INTERIOR AND ITS LINKS TO THE CLIMATE SYSTEM, INCLUDING RESEARCHERS FROM UNDERREPRESENTED GROUPS, AND VARIED COUNTRIES AND INSTITUTIONS. WE WILL IMPLEMENT STRATEGIES TO CREATE AN INCLUSIVE MEETING ENVIRONMENT, WHERE EVERYONE IS FREE TO SHARE THEIR IDEAS IN PLENARY DISCUSSIONS, POSTER SESSIONS, MEALS, FREE AFTERNOONS, AND A ?POWER HOUR? DISCUSSION FOCUSED ON CAREERS AND COMMUNITY-BUILDING. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

2025 BIOLOGY OF AGING GORDON RESEARCH CONFERENCE AND SEMINAR - PROJECT SUMMARY THIS APPLICATION REQUESTS FUNDS TO SUPPORT THE 2025 GORDON RESEARCH CONFERENCE (GRC) ON THE BIOLOGY OF AGING, TO BE HELD AT THE RENAISSANCE TUSCANY IL CIOCCO IN BARGA (ITALY) ON AUGUST 3 – 8, 2025, AND THE GORDON RESEARCH SEMINAR (GRS), WHICH WILL BE HELD AT THE SAME LOCATION ON AUGUST 2 – 3, 2025, IMMEDIATELY PRIOR TO THE GRC. THIS WILL BE THE SEVENTEENTH BIOLOGY OF AGING MEETING SINCE ITS ORIGIN IN 1962. THIS MEETING IS UNIQUE IN ITS DIVERSITY, REFLECTED IN THE THEME OF THE 2025 CONFERENCE: “BIOLOGY OF AGING ACROSS SCALES: MOLECULAR, CELLULAR, ORGANISMAL”. OVER RECENT DECADES, THE FIELD HAS MADE REMARKABLE PROGRESS IN ELUCIDATING THE KEY HALLMARKS OF AGING AT INCREASINGLY REFINED MOLECULAR AND CELLULAR LEVELS. THESE ADVANCES HAVE FOSTERED A PARADIGM SHIFT IN OUR UNDERSTANDING OF AGING, REVEALING IT TO BE A MALLEABLE PROCESS AMENABLE TO INTERVENTION. THIS PLASTICITY EXTENDS BEYOND CELLULAR MODELS AND INVERTEBRATES, ENCOMPASSING A WIDE RANGE OF VERTEBRATES AND EVEN HUMANS. AT THE SAME TIME, RAPID TECHNOLOGICAL INNOVATIONS AND THE DIVERSIFICATION OF EXPERIMENTALLY TRACTABLE MODEL ORGANISMS HAVE ENABLED RESEARCHERS TO EXAMINE AGING FROM A MORE HOLISTIC PERSPECTIVE. WE NOW HAVE A FAR MORE NUANCED PORTRAIT OF AGING, OFFERING UNPRECEDENTED INSIGHTS INTO THE INTRICATE INTERPLAY BETWEEN THE IMMUNE SYSTEM, THE BRAIN, THE GENOME, AND THE AGING PROCESS ITSELF. THIS HAS ALSO OPENED NEW AVENUES FOR POTENTIAL THERAPEUTIC INTERVENTIONS ACROSS VARIOUS BIOLOGICAL SCALES. BIOLOGY OF AGING GRC WILL HIGHLIGHT SOME OF THESE EMERGING TOP-DOWN APPROACHES TO UNDERSTANDING AGING WITH A FOCUS ON REPRODUCTIVE AGING, INTERTISSUE SIGNALING, EPI/GENETICS, AND COMPARATIVE BIOLOGY. OUR GOAL IS TO REMAIN THE PREMIER FORUM FOR COALESCING THE FIELD AND FOSTERING THE DISCUSSION OF CONCEPTS AND PRESENTATION OF UNPUBLISHED RESEARCH AT THE FOREFRONT OF DISCOVERY RELATED TO SYSTEMIC AGING. FUNDS ARE REQUESTED TO HELP COVER EXPENSES OF INVITED SPEAKERS, MERITORIOUS JUNIOR SCIENTISTS AND MINORITY TRAINEES WHO WILL BENEFIT FROM FORMAL AND INFORMAL INTERACTIONS WITH SENIOR SCIENTISTS, TO PRESENT THEIR RESEARCH FINDINGS, RECEIVE FEEDBACK FROM EXPERTS IN THE FIELD, AND EXCHANGE IDEAS FOR SHAPING THE FIELD. INVITED SPEAKERS INCLUDE ESTABLISHED AS WELL AS OUTSTANDING EARLY CAREER SCIENTISTS SELECTED FOR THE QUALITY OF THEIR SCIENCE AND ABILITY TO STIMULATE DEBATE. WE WILL PROVIDE A FORUM FOR BOTH FORMAL AND INFORMAL INTERACTIONS BETWEEN TRAINEES AND FACULTY AT ALL STAGES TO PROMOTE THE EXCHANGE OF IDEAS AND COLLABORATIVE SYNERGIES AROUND REPRODUCTIVE AGING. POSTER AND ORAL PRESENTATIONS WILL EXAMINE AGING AT THE MOLECULAR, CELLULAR AND ORGANISMAL LEVEL, INCLUDING ITS MOLECULAR DRIVERS, AND THE EFFECTS OF GENETIC AND ENVIRONMENTAL FACTORS ON RELEVANT CELLULAR/SYSTEM PROPERTIES, INTERACTIONS, AND INTERVENTIONS ACROSS DIVERSE MODEL SYSTEMS RANGING FROM WORMS TO HUMANS. THIS UNIQUE CONFERENCE WILL BRING TOGETHER SCIENTISTS TACKLING THIS PROBLEM FROM FUNDAMENTAL TO CLINICAL ANGLES TO BRAINSTORM CREATIVE WAYS TO BUILD AND STRENGTHEN THE FIELD.

CONFERENCE: 2025 CHEMICAL OCEANOGRAPHY GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR -THIS AWARD WILL PROVIDE TRAVEL AND REGISTRATION SUPPORT FOR ATTENDEES OF THE 2025 GORDON RESEARCH CONFERENCE (GRC) IN CHEMICAL OCEANOGRAPHY AND THE ASSOCIATED GORDON RESEARCH SEMINAR. THE FIELD OF CHEMICAL OCEANOGRAPHY ADDRESSES MANY ISSUES OF BROADER SOCIETAL IMPORTANCE, SUCH AS THE FATE OF HUMAN INPUTS TO THE OCEAN, SUSTAINABILITY OF OCEAN ECOSYSTEMS, AND THE SCIENTIFIC UNDERPINNINGS OF PROPER MANAGEMENT OF COASTAL AND OPEN OCEANS. THE CHEMICAL OCEANOGRAPHY GRC BRINGS TOGETHER SCIENTISTS FROM ALL CAREER STAGES AND DIFFERENT PARTS OF THE CHEMICAL OCEANOGRAPHY RESEARCH FIELD TO DISCUSS THEIR NEWEST IDEAS. THE GORDON RESEARCH SEMINAR IS A TWO-DAY WORKSHOP PRIOR TO THE GRC MEETING, FOCUSED ON MENTORING AND COHORT-BUILDING AMONG RESEARCHERS NEW TO THE FIELD. THE 2025 GORDON RESEARCH CONFERENCE WILL BE HELD IN JULY 2025 AT SOUTHERN NEW HAMPSHIRE UNIVERSITY. THE THEME OF THIS YEAR?S CONFERENCE IS ?FINGERPRINTS IN THE OCEAN,? REFLECTING HOW THE DISCIPLINE OF CHEMICAL OCEANOGRAPHY USES CHEMICAL FINGERPRINTS LEFT BY PHYSICAL, CHEMICAL, BIOLOGICAL, AND GEOLOGICAL PROCESSES TO UNDERSTAND THE OCEAN. NINE TOPICAL SESSIONS WILL SHOWCASE RESEARCH ADVANCES IN THE CHEMICAL TOOLS USED BY THE SCIENTIFIC COMMUNITY TO STUDY THE OCEAN AND HOW IT IS CHANGING. THE SESSIONS COVER COASTAL BIOGEOCHEMICAL PROCESSES, NATURAL AND ANTHROPOGENIC CARBON CYCLING, INSIGHTS FROM AUTONOMOUS OBSERVATIONS, MOLECULAR CHEMICAL OCEANOGRAPHY, TRACE ELEMENTS AND ISOTOPES, BIOGEOCHEMICAL MODELLING, A SESSION DEVOTED TO MARINE CARBON DIOXIDE REMOVAL (MCDR), AND WHAT SEDIMENTS TELL US ABOUT PAST AND PRESENT BIOGEOCHEMICAL CYCLING. INTEREST IN MCDR HAS EXPANDED RAPIDLY IN ACADEMIC, GOVERNMENTAL, AND ENTREPRENEURIAL CIRCLES, AND CHEMICAL OCEANOGRAPHERS ARE UNIQUELY QUALIFIED TO ADDRESS THE FUNDAMENTAL BASES FOR MCDR STRATEGIES. THIS YEAR?S CONFERENCE WILL PROVIDE A FORUM FOR EXAMINING SEVERAL OF THESE STRATEGIES IN THE CONTEXT OF OTHER FUNDAMENTAL ADVANCES IN CHEMICAL OCEANOGRAPHY. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

CONFERENCE: 2026 OCEAN MIXING GRC/GRS: COMPETING ENERGY CASCADES AND THEIR IMPLICATIONS FOR OCEAN MIXING ACROSS A SPECTRUM OF ENVIRONMENTS -THIS PROJECT IS TO SUPPORT THE GORDON RESEARCH CONFERENCE ON OCEAN MIXING AND THE GORDON RESEARCH SEMINAR FOR EARLY CAREER SCIENTISTS. THE CONFERENCE AND SEMINAR WILL PROVIDE A FORUM TO IMPROVE THE UNDERSTANDING OF TURBULENT MIXING IN THE OCEAN, INCLUDING THE INTERACTIONS ACROSS SCALES, AND THE APPLICATIONS TO PROBLEMS SUCH AS WEATHER PREDICTION AND OCEAN FORECASTS AND SOLUTIONS. THE GORDON RESEARCH CONFERENCE FORMAT IS DESIGNED TO GENERATE VIGOROUS DISCUSSION AND FOSTER NEW COLLABORATIONS, STIMULATING NEW UNDERSTANDING. THE CHAIRS, VICE CHAIRS, AND DISCUSSION LEADERS HAVE A DEEP FAMILIARITY WITH THE FIELD AND AS SUCH HAVE DESIGNED A PROGRAM THAT HIGHLIGHTS CUTTING-EDGE RESEARCH IN OCEAN MIXING. THE CONFERENCE WILL STRENGTHEN THE CONNECTION BETWEEN FUNDAMENTAL STUDIES OF OCEAN MIXING AND APPLICATIONS TO SOCIETALLY RELEVANT PROBLEMS SUCH AS PREDICTABILITY OF CURRENTS AND WEATHER, FISHERIES, AND THE UTILIZATION OF OCEAN RESOURCES SUCH AS MINERALS IN THE SEABED. IT WILL ALSO LEAD TO WORKFORCE DEVELOPMENT BY PROMOTING NEW INTERACTIONS BETWEEN PEOPLE WORKING ON DIFFERENT ASPECTS OF OCEAN MIXING, USING DIFFERENT APPROACHES, AND AT VARIED CAREER LEVELS, THROUGH FOCUSED DISCUSSIONS AND FACILITATED INFORMAL NETWORKING ACTIVITIES. NSF SUPPORT WILL BE EXPLICITLY USED TO SUPPORT ATTENDANCE OF EARLY CAREER SCIENTISTS. OCEAN MIXING IS TIME-VARIABLE MOTION WHICH INCREASES FLUXES OF TRACERS ABOVE LEVELS SET BY MOLECULAR DIFFUSION, ENCOMPASSES A WIDE VARIETY OF PROCESSES TAKING PLACE OVER A LARGE RANGE OF SCALES, FROM THE 10-100 KILOMETER SCALES OF MESOSCALE GEOSTROPHIC EDDIES DOWN TO THE SMALLEST SCALES OF ISOTROPIC TURBULENCE. BETWEEN THESE SCALES MANY DIFFERENT INSTABILITY PROCESSES EXCITE MOTIONS WHICH LEAD TO MIXING. THESE PROCESSES, EXCEPT FOR THE LARGEST MESOSCALE EDDIES, HAVE IN COMMON SCALES WHICH ARE TOO SMALL TO EXPLICITLY SIMULATE, REQUIRING PARAMETERIZATIONS OF THEIR IMPACT ON TRACER FLUXES TO ACCURATELY CAPTURE THEIR EFFECT ON THE LARGE-SCALE OCEAN. THE DEVELOPMENT OF PARAMETERIZATIONS REQUIRES EXPERTS IN DIFFERENT ASPECTS OF OCEAN MIXING - OBSERVATIONS, THEORY, PROCESS SIMULATION, LABORATORY EXPERIMENTS, REGIONAL AND GLOBAL SCALE MODELING - TO WORK TOGETHER. THE GORDON RESEARCH CONFERENCE IS INTENDED TO STIMULATE THIS COLLABORATION BETWEEN SCIENTISTS USING DIFFERENT APPROACHES AND FOCUSED ON DIFFERENT SCALES, TO BETTER UNDERSTAND THE DIFFICULT PROBLEM OF OCEAN TURBULENCE. WHILE OCEAN MIXING IS STILL POORLY UNDERSTOOD, IT HAS IMPORTANT IMPACTS IN MANY AREAS OF RELEVANCE. SMALL-SCALE MIXING PROCESSES ARE RECOGNIZED TO PLAY AN IMPORTANT ROLE IN SETTING THE STRATIFICATION OF THE OCEAN, FLUXES OF HEAT AND CHEMICAL CONSTITUENTS BETWEEN THE OCEAN AND ADJACENT ATMOSPHERE OR ICE, FLUXES OF NUTRIENTS INTO THE EUPHOTIC ZONE, AND OCEAN OVERTURNING LEADING TO IMPACTS ON THE PREDICTABILITY OF CURRENTS AND WEATHER, FISHERIES, AND THE UTILIZATION OF OCEAN RESOURCES SUCH AS MINERALS IN THE SEABED. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

2023 BIOLOGY OF AGING GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR - PROJECT SUMMARY THIS APPLICATION REQUESTS FUNDS TO SUPPORT THE 2023 GORDON RESEARCH CONFERENCE (GRC) ON THE BIOLOGY OF AGING, TO BE HELD AT REY DON JAIME GRAND HOTEL IN CASTELLDEFELS (SPAIN) ON JULY 2–7, 2023, AND THE GORDON RESEARCH SEMINAR (GRS), WHICH WILL BE HELD AT THE SAME LOCATION ON JULY 1–2, 2023, IMMEDIATELY PRIOR TO THE GRC. THIS WILL BE THE SIXTEENTH BIOLOGY OF AGING MEETING SINCE ITS ORIGIN IN 1962. WHILE GERIATRICS AND GERONTOLOGY SOCIETIES AND THEIR CONFERENCES HAVE FOCUSED ON THE MEDICAL, SOCIAL, AND PSYCHOLOGICAL CONSEQUENCES OF AGING, IN THE MOST RECENT TWO DECADES THERE HAS BEEN AN EXPLOSION OF KNOWLEDGE ON UNDERLYING MECHANISMS OF THE AGING PROCESS. WHILE THE BIOLOGY OF AGING IS STILL A RELATIVELY NEW FIELD, THIS GRC HAS BECOME THE PREMIER FORUM FOR UNPUBLISHED DATA PRESENTATION AND DISCUSSIONS, RESULTING IN A MEETING WHERE ONE CAN VIEW EXCITING CURRENT SCIENCE AND SEE THE FUTURE DIRECTIONS OF THE FIELD. THIS MEETING IS UNIQUE IN ITS DIVERSITY, REFLECTED IN THE THEME OF THE 2023 CONFERENCE: “EVOLVING CONCEPTS OF ORGANISMAL AGING”. AGING RESEARCH OVER THE PAST DECADES HAS MADE GREAT STRIDES TO IDENTIFY KEY HALLMARKS OF AGING AT AN INCREASINGLY DETAILED MOLECULAR AND CELLULAR RESOLUTION. THESE ADVANCES HAVE LED TO THE GROWING RECOGNITION THAT AGING IS MALLEABLE AND SUBJECT TO INTERVENTIONS NOT JUST AT THE CELLULAR LEVEL OR IN INVERTEBRATES BUT POSSIBLY IN A RANGE OF VERTEBRATES AND EVEN HUMANS. AT THE SAME TIME, RAPID ADVANCES IN TECHNOLOGY AND THE EXPANSION OF THE EXPERIMENTALLY TRACTABLE MODEL ORGANISMS HAVE FACILITATED THE STUDY OF AGING FROM AN EVER-BROADER PERSPECTIVE OF ENTIRE COMPLEX ORGANISMS. THESE STUDIES PAINT A MUCH MORE INTRICATE PICTURE OF SYSTEMIC AGING, AND THEY OFFER UNPRECEDENTED NEW INSIGHT INTO INTERACTIONS BETWEEN HOST DEFENSE, THE CENTRAL NERVOUS SYSTEM, MICROBIOTA, AND THE PROCESS OF AGING. THIS GRC WILL HIGHLIGHT SOME OF THESE EMERGING TOP-DOWN APPROACHES TO UNDERSTANDING AGING WITH A FOCUS ON IMMUNE AGING, NEURAL CONTROL, AND THE MICROBIOME. PARTICIPATING SCIENTISTS WILL PRESENT BASIC STUDIES IN INVERTEBRATE MODEL ORGANISMS, AS WELL AS STUDIES IN HIGHER ORGANISMS. APPROPRIATELY, THE TALKS AND POSTERS WILL REFLECT THE DIVERSITY OF THE BIOLOGY OF AGING BY RANGING FROM MOLECULAR STUDIES TO UNDERSTANDING HOW AGING IMPACTS NUMEROUS CELLULAR AND ORGAN SYSTEMS AND ORGANISMS. WE WILL ALSO HEAR EXCITING WORK ON INTERVENTIONS TO MODULATE AGING. THE MEETING WILL INCORPORATE A PANEL DISCUSSION, MENTORING LUNCH, AND NUMEROUS NETWORKING OPPORTUNITIES. OUR MULTIFACETED APPROACH TO MEET THE OBJECTIVES OF THIS MEETING INCLUDE: I) A PROGRAM RICH IN SCIENTIFIC DIVERSITY OF TOPIC AND APPROACH; II) AN ATMOSPHERE TO PROMOTE INTERDISCIPLINARY COLLABORATIONS AND STIMULATE SCIENTIFIC EXCHANGE; III) MENTORING OPPORTUNITIES TO PROMOTE INTERACTIONS BETWEEN JUNIOR INVESTIGATORS AND SENIOR, ESTABLISHED INVESTIGATORS; AND IV) SUPPORT OF INDIVIDUAL DIVERSITY IN PARTICIPATION.

CONFERENCE: 2024 CLIMATE ENGINEERING GRC AND GRS -THE 2024 GORDON RESEARCH CONFERENCE (GRC) ON CLIMATE ENGINEERING (CE) WILL BE HELD FEBRUARY 18-23, 2024 IN LUCCA, ITALY. THE CONFERENCE WILL FEATURE BOTH SENIOR AND JUNIOR SCIENTISTS WHO RECENTLY HAVE BEEN ACTIVE IN THE FIELD AND ARE LEADING NEW RESEARCH DIRECTIONS IN CLIMATE ENGINEERING RESEARCH. SCIENTISTS AND ENGINEERS SPANNING RESEARCHERS WHO DID SOME OF THE FIRST WORK IN THIS AREA TO STUDENTS CURRENTLY BASING THEIR GRADUATE RESEARCH IN CLIMATE ENGINEERING ARE ANTICIPATED TO ATTEND. THE GORDON RESEARCH SEMINAR (GRS), DESIGNED FOR YOUNG SCIENTISTS, WILL PRECEDE THE GRC AT THE SAME LOCATION ON FEBRUARY 17 AND 18. THIS GRANT IS FOR PARTIAL SUPPORT OF US-BASED INVITED SPEAKERS, DISCUSSION LEADERS AND OTHERS, IN PARTICULAR EARLY-CAREER SCIENTISTS, TO ATTEND THE GRS AND GRC. AREAS TO BE DISCUSSED INCLUDE: THE ENGINEERING AND TECHNICAL FEASIBILITY OF CLIMATE ENGINEERING APPROACHES; HOW IMPLEMENTATION OF CE WOULD AFFECT CLIMATE IMPACTS; DETECTABILITY AND INTERPRETATION OF IMPACTS, INCLUDING SOCIETAL AND ECOLOGICAL CONSIDERATIONS; AND APPROACHES FOR DESIGNING INJECTION STRATEGIES AND CE SCENARIOS TO STUDY THE OUTCOMES OF DIFFERENT CE APPLICATIONS UNDER DIFFERENT CLIMATE SCENARIOS. RESEARCH TO BE DISCUSSED ALSO INCLUDES IMPROVING CONFIDENCE IN EARTH SYSTEM MODELS THROUGH EVALUATION WITH OBSERVATIONS AND MODEL INTERCOMPARISONS. THE STUDY OF CLIMATE ENGINEERING IS BY NATURE INTERDISCIPLINARY, RELYING ON INFORMATION EXCHANGE AND IN-DEPTH DISCUSSIONS BETWEEN DIFFERENT GROUPS, AS PROVIDED BY THE GRC AND GRS. CLIMATE CHANGE IS CONTINUING TO CAUSE LARGE-SCALE IMPACTS AND EXTREME EVENTS ALL OVER THE WORLD. CLIMATE ENGINEERING VIA SOLAR RADIATION MODIFICATION (SRM) MAY BE THE ONLY OPTION TO SUSTAIN GLOBAL TEMPERATURES IN THE NEAR TERM. HOWEVER, UNDERSTANDING OF THE FEASIBILITY AND IMPACTS OF DIFFERENT SRM APPROACHES IS STILL VERY LIMITED, WHICH IS LIMITING ABILITY TO MAKE WELL-INFORMED DECISIONS ABOUT THEIR POSSIBLE USE. FURTHERMORE, THE NEEDED TECHNOLOGIES HAVE NOT BEEN DEVELOPED. THERE IS THEREFORE AN URGENT NEED TO ACCELERATE CLIMATE ENGINEERING RESEARCH, IDEALLY BRINGING FRAGMENTED RESEARCH AREAS TOGETHER TOWARDS MORE FOCUSED WORK. THE GRC AND GRS ARE EXCELLENT VENUES TO DISCUSS CUTTING-EDGE CE RESEARCH AND IDEAS AND TO INTEGRATE AN INTERDISCIPLINARY GROUP OF SCIENTISTS TO MOVE THE RESEARCH FORWARD. THIS 2024 GRC/GRS FOR CLIMATE ENGINEERING IS LOCATED IN ITALY, WITH THE PURPOSE OF ALLOWING RESEARCHERS FROM ALL OVER THE WORLD, AND IN PARTICULAR FROM DEVELOPING COUNTRIES, TO MORE EASILY ATTEND. THE GRS WILL PLAY AN IMPORTANT ROLE IN INTRODUCING AND INTEGRATING EARLY CAREER SCIENTISTS AND STUDENTS INTO CRITICAL TOPIC AREAS OF CE RESEARCH. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

2021 STRESS PROTEINS IN GROWTH, DEVELOPMENT, AND DISEASE GRC/GRS - PROJECT SUMMARY THE VIABILITY OF CELLS, TISSUES, AND ORGANISMS CRITICALLY DEPEND ON THE MAINTENANCE OF PROTEIN HOMEOSTASIS (PROTEOSTASIS) AND THUS, CONSTANT ADAPTATION OF THE CELLULAR PROTEOME TO EXTERNAL AND INTERNAL ALTERATIONS MUST BE MADE TO SUSTAIN HEALTH. PHYSIOLOGICAL CHALLENGES INCLUDING TRANSITIONS THROUGH NORMAL DEVELOPMENTAL STAGES, FLUCTUATING ENVIRONMENTAL CONDITIONS BRINGING ACUTE STRESS CONDITIONS SUCH AS TEMPERATURE, OXIDATION AND INFLAMMATION STRESS, OR CHRONIC STRESS CONDITIONS CAUSED BY DNA MUTATIONS OR AGING MUST BE MANAGED. ALL THESE INCIDENTS CONSTITUTE RISK FACTORS PROVOKING A LOSS OF CELLULAR HOMEOSTASIS THAT CAN LEAD TO PROTEIN MISFOLDING/AGGREGATION AND, FINALLY, CELL DEATH. SUCH A DECLINE IN PROTEOSTASIS IS ESPECIALLY PROMINENT DURING AGING AND IN CERTAIN DISEASE SETTINGS INCLUDING NEURODEGENERATION, CANCER, CARDIOVASCULAR, OR METABOLIC (E.G. DIABETES). THUS, THE ABILITY OF CELLS TO SENSE AND RESPOND TO CHANGING CONDITIONS INCLUDING STRESS IS CRITICAL FOR NORMAL CELL GROWTH AND DEVELOPMENT AS WELL AS PROTECTING ORGANISMS AGAINST AGING DISEASES. A GROWING BODY OF EVIDENCE ILLUSTRATES THAT CELLS USE AN ELABORATE PROTEIN QUALITY CONTROL NETWORK TO ADAPT TO CHANGING CONDITIONS INCLUDING SPECIFIC SIGNALING REGIMES, TRANSCRIPTIONAL AND TRANSLATIONAL REPROGRAMMING, AND ACTIVATION OF CELLULAR QUALITY CONTROL SYSTEMS SUCH AS PROTEOLYTIC AND MOLECULAR CHAPERONES PATHWAYS. THESE NOT ONLY ENSURE A HEALTHY AND FUNCTIONAL PROTEOME BUT ALSO ASSIST TO PREVENT THE ACCUMULATION OF TOXIC MISFOLDED AND AGGREGATED PROTEINS KNOWN TO PLAY A CRITICAL ROLE IN LIFE-SPAN REGULATION AND AGING-RELATED DISORDERS SUCH AS ALZHEIMER'S, PARKINSON'S, HUNTINGTON'S DISEASES AS WELL AS PRION-BASED DISEASE. THE 2021 GRC ON "STRESS PROTEINS IN GROWTH, DEVELOPMENT AND DISEASE" TO BE HELD JULY 18-23, 2021 AT REY DON JAIME GRAND HOTEL IN SPAIN IS THE 11TH IN THIS SUCCESSFUL SERIES AND WILL HIGHLIGHT THE MOST RECENT CUTTING EDGE ADVANCES IN THE FIELD OF PROTEOSTASIS BIOLOGY RANGING FROM UNDERLYING BASIC MECHANISMS OF STRESS PROGRAMS AND OF PROTEIN QUALITY CONTROL SYSTEMS UP TO INTERVENTION STRATEGIES ALONG WITH HOW AGING INTERSECTS WITH EACH. SPECIAL EMPHASIS WILL BE PLACED ON NOVEL ASPECTS REGARDING STRESS SIGNALING, REGULATION OF GENE EXPRESSION AND PROTEIN TRANSLATION, PHASE SEPARATION AND OTHER SPECIFIC DEPOSITS OF PROTEINS UNDER AGING AND STRESS, ELIMINATION STRATEGIES OF TOXIC PROTEIN SPECIES, AND THE ROLE OF ORGANELLE STRESS RESPONSES TO PATHOLOGY. ADDITIONALLY, WE WILL CONTINUE A SUCCESSFUL MEETING INNOVATION: A GRS WILL OCCUR FROM JULY 17-18TH TO PROMOTE THE DEVELOPMENT OF JUNIOR INVESTIGATORS IN THE FIELD. POSTER TEASER TALKS, CAREER ROUNDTABLE DISCUSSIONS, AND A POWERHOUR FOCUSED ON WOMEN INVESTIGATORS WILL COMPLETE THIS CONFERENCE. THE FORMAL SCIENTIFIC PROGRAM, LIMITED ATTENDANCE, AND ORGANIZED BUT INFORMAL OPPORTUNITIES FOR INTERACTION MAKE THIS MEETING A PREEMINENT CONFERENCE AT THE FOREFRONT OF SCIENCE PROMOTING A DEEPER UNDERSTANDING OF THE IMPACT OF STRESS PROTEINS IN HUMAN AGING, HEALTH, AND DISEASE AND THE DEVELOPMENT OF EFFICIENT COUNTERMEASURES. THE CHAIR IS DR. BRAIN C. FREEMAN AND THE VICE-CHAIR IS DR. HARM H. KAMPINGA.

CONFERENCE: 2024 ROCK DEFORMATION GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR -THIS PROJECT PROVIDES TRAVEL AND REGISTRATION COSTS FOR GRADUATE STUDENTS, EARLY CAREER RESEARCHERS AND PRESENTERS TO ATTEND THE 2024 GORDON RESEARCH CONFERENCE AND SEMINAR ON ROCK DEFORMATION. THE CONFERENCE WILL BE HELD FROM AUGUST 3RD TO AUGUST 9TH, 2024 AT BATES COLLEGE IN LEWISTON, MAINE. THE GORDON RESEARCH CONFERENCES AND SEMINARS PROVIDE AN INTERNATIONAL FORUM FOR THE PRESENTATION AND DISCUSSION OF FRONTIER SCIENTIFIC RESEARCH. THE PRESENTATIONS AND DISCUSSIONS WILL SPAN A VARIETY OF TOPICS PERTAINING TO ROCK DEFORMATION, INCLUDING MECHANICS OF ICY MATERIALS, DEFORMATION OF NEAR-SURFACE MATERIALS, FAULT HETEROGENEITY AND SLIP BEHAVIOR, EARTHQUAKE PROCESSES AND HAZARDS, THE BRITTLE-DUCTILE TRANSITION, DEEP SUBDUCTION PROCESSES, LOWER CRUSTAL DYNAMICS, AND MANTLE RHEOLOGY. THE GORDON RESEARCH CONFERENCES AND SEMINARS PROVIDE A UNIQUE OPPORTUNITY FOR EARLY-CAREER SCIENTISTS TO COME TOGETHER IN A HIGHLY STIMULATING AND NON-INTIMIDATING ENVIRONMENT TO DISCUSS CURRENT RESEARCH AND BUILD NETWORKS THAT CAN LEAD TO A LIFETIME OF COLLABORATION AND SCIENTIFIC ACHIEVEMENT. IN ADDITION, THE PROJECT WILL CONTRIBUTE TO BROADENING OF PARTICIPATION OF UNDERREPRESENTED GROUPS IN SCIENCE, TECHNOLOGY, AND MATHEMATICS (STEM) THROUGH RECRUITMENT OF PARTICIPANTS FROM UNDERREPRESENTED GROUPS. THE GORDON RESEARCH CONFERENCE AND ASSOCIATED GORDON RESEARCH SEMINAR WILL FOSTER DEVELOPMENT OF NEW RESEARCH DIRECTIONS IN ROCK DEFORMATION AND WILL CONTRIBUTE TO THE DEVELOPMENT OF A DIVERSE AND GLOBALLY COMPETITIVE STEM WORKFORCE. THE CONFERENCE PROGRAM INCLUDES TOPICS OF SOCIETAL RELEVANCE THAT BEAR ON THE UNDERSTANDING OF GEOLOGIC HAZARDS SUCH AS EARTHQUAKES AND LANDSLIDES, CLIMATE HAZARDS SUCH AS GLACIAL MOTION, AND GREEN ENERGY SOLUTIONS SUCH AS GEOTHERMAL ENERGY EXTRACTION. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

GRC ON UNDERGRADUATE BIOLOGY EDUCATION RESEARCH: IMPROVING DIVERSITY, EQUITY, AND LEARNING

2024 GEOBIOLOGY GORDON RESEARCH CONFERENCE AND SEMINAR

CONFERENCE: 2026 GEOBIOLOGY GORDON RESEARCH CONFERENCE AND SEMINAR -THIS PROJECT SUPPORTS THE PARTICIPATION OF EARLY CAREER SCIENTISTS IN THE 2026 GEOBIOLOGY GORDON RESEARCH SEMINAR AND GORDON RESEARCH CONFERENCE. GEOBIOLOGY IS THE STUDY OF INTERACTIONS BETWEEN LIFE AND THE PHYSICAL EARTH, BOTH IN THE MODERN AND ANCIENT WORLDS. IT MERGES THE DISCIPLINES OF PALEONTOLOGY, SEDIMENTOLOGY, MICROBIOLOGY, CHEMISTRY, AND GEOLOGY. AT THE HEART OF THE FIELD OF GEOBIOLOGY IS HOW THE LIVING PLANET AND ITS CHANGES OVER TIME ARE DOCUMENTED, UNDERSTOOD, AND INTERPRETED. THIS, IN TURN, LEADS TO QUESTIONS OF WHAT CONTROLS THE VARIETY OF METABOLISMS ON THE PLANET TODAY, AS WELL AS THE ROLE THAT MICROBES PLAY IN THE FORMATION AND CHANGE OF EARTH?S SURFACE. THROUGHOUT THIS CONFERENCE, PARTICIPANTS WILL EXPLORE THE PHYSIOLOGICAL LIMITS OF LIFE, THE ROLE THAT MICROBIAL POPULATIONS PLAY IN KEY PROCESSES INCLUDING THE FORMATION OF MINERALS (ESPECIALLY THOSE CRITICAL TO HUMANS), THE LINKS BETWEEN MICROBES AND GEOCHEMICAL PROCESSES, AND EMERGING ANALYTICAL/NUMERICAL TOOLS TO FURTHER INVESTIGATE THESE IDEAS. THE 2026 GORDON RESEARCH CONFERENCE WILL ENABLE THE EXCHANGE OF IDEAS, TOOLS, AND EXPERTISE TO PROMOTE COLLABORATION AMONG SCIENTISTS TO HELP HUMAN SOCIETY AND BUILD A MORE COHESIVE STEM WORKFORCE. THE CONFERENCE WILL HIGHLIGHT OPEN QUESTIONS, APPLICATIONS OF GEOBIOLOGICAL TECHNIQUES TO PRIVATE INDUSTRY, AND NEW EXPERIMENTAL APPROACHES IN THE FIELD. THIS CONFERENCE WILL GATHER ~150 SCIENTISTS, STUDENTS, AND POSTDOCTORAL RESEARCH FELLOWS WITHIN THE FIELD OF GEOBIOLOGY. THE SCIENTIFIC SESSIONS ARE CENTERED AROUND NINE THEMES, EACH OF WHICH IS KEY TO UNDERSTANDING THE ROLE OF LIFE ON A LIVING PLANET. THIS CONFERENCE AND THE ACCOMPANYING GORDON RESEARCH SEMINAR (WHICH FOCUSES SOLELY ON GRADUATE STUDENTS AND POSTDOCTORAL SCHOLARS) WILL INCLUDE SESSIONS WITH INVITED SPEAKERS, DISCUSSION LEADERS, AND POSTER SESSIONS. PARTICIPANTS ATTEND ALL SESSIONS AND EAT ALL MEALS IN SUCCESSION TOGETHER TO ENSURE A FOCUSED MEETING AND FOSTER INTERACTIONS AMONG ACTIVE AND JUNIOR SCIENTISTS. ANTICIPATED OUTCOMES INCLUDE ADVANCES IN ANALYTICAL/NUMERICAL TOOLS, AS WELL AS MORE UNIFORM DATA QUALITY STANDARDS IN VARIOUS SUBDISCIPLINES. THE FORMAT OF THE CONFERENCE, THE RANGE OF TOPICS, AND THE INTERACTIVE COMMUNITY OF PEOPLE ENGAGED IN ACTIVE RESEARCH WILL FOSTER INCREASED PARTICIPATION IN GEOBIOLOGY. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

CONFERENCE: 2024 GEOBIOLOGY GRC/GRS -THIS FUNDING SUPPORTS THE GEOBIOLOGY GORDON RESEARCH SEMINAR (GRS) AND GORDON RESEARCH CONFERENCE (GRC) IN GALVESTON, TX FROM JANUARY 13 TO 19, 2024. THE FIELD OF GEOBIOLOGY INVESTIGATES LIFE AND THE ENVIRONMENT OVER EARTH HISTORY, INCLUDING BOTH MODERN PHENOMENA AND SOCIETALLY-RELEVANT IMPACTS ON THE FUTURE. IN RECENT YEARS, THE FIELD HAS PRODUCED A STRONG COHORT OF GEOBIOLOGISTS, AND THE GRS AND GRC SERVE TO STRENGTHEN THE COMMUNITY AND ENHANCE COMMUNICATION ACROSS SUBGROUPS AND DISCIPLINES. THE 2024 GEOBIOLOGY GRS AND GRC OFFERS NUMEROUS FORMAL AND INFORMAL OPPORTUNITIES TO SOCIALIZE AND NETWORK. THE SETTING AND SIZE (60 AND 200 PARTICIPANTS MAXIMUM) PROMOTE CONNECTIONS BETWEEN JUNIOR AND SENIOR COLLEAGUES. THE FUNDING WILL SUPPORT THE ATTENDANCE OF 25 PARTICIPANTS, PRIORITIZING SCIENTISTS WHO ARE EARLY CAREER AND FROM UNDERREPRESENTED BACKGROUNDS. THE 2024 CONFERENCE WILL BRING TOGETHER THESE DIVERSE SCIENTISTS WHO WORK IN DIFFERENT GEOBIOLOGY DISCIPLINES TO ENABLE THE EXCHANGE OF IDEAS, TOOLS, AND EXPERTISE TO PROMOTE FURTHER CROSS-POLLINATION AND DEVELOPMENT OF THESE DISCIPLINES. GEOBIOLOGY USES THE TOOLS OF PALEONTOLOGY, GEOLOGY, GEOCHEMISTRY, MICROBIOLOGY, AND ENGINEERING BUT IS SEPARATED FROM THESE MORE TRADITIONAL DISCIPLINES BY AN INTEREST IN THE COMPLEX RELATIONSHIPS AND FEEDBACKS AMONG BIOLOGICAL, CHEMICAL, AND PHYSICAL PROCESSES, LARGE SPATIAL SCALES, AND EVOLUTIONARY TIMESCALES. THE CONFERENCE FACILITATES INTERACTIONS AMONG SUB-DISCIPLINES TO UNDERSTAND THE ONGOING CO-EVOLUTION OF LIFE AND THE ENVIRONMENT. THE SESSIONS FOR GEOBIOLOGY GRC/GRS 2024 FOCUS ON ADDRESSING THE OUTSTANDING QUESTIONS IN THE FIELD, AND HOW GEOBIOLOGISTS CAN USE THEIR KNOWLEDGE TO MITIGATE ANTHROPOGENIC PROBLEMS AND UNDERSTAND LIFE?S IMPACTS ON EARTH AND BEYOND. GORDON RESEARCH CONFERENCES ENCOURAGE OPEN AND HONEST INTELLECTUAL DEBATE AS PART OF A WELCOMING, INCLUSIVE ATMOSPHERE AND EACH SESSION CHAIR FOSTERS RIGOROUS ANALYSIS OF ALL SCIENCE IN A MANNER RESPECTFUL TO ALL CONFEREES. THESE INTERACTIONS ADVANCE DISCOVERY AND UNDERSTANDING ACROSS GEOBIOLOGY WHILE PROMOTING MENTORSHIP, TRAINING AND COMMUNITY. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

2024 ALCOHOL AND THE NERVOUS SYSTEM GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR - PROJECT SUMMARY/ABSTRACT THIS R13 APPLICATION REQUESTS SUPPORT FOR THE GORDON RESEARCH CONFERENCE (GRC) AND THE ASSOCIATED GRS ON ALCOHOL AND THE NERVOUS SYSTEM THAT WILL TAKE PLACE IN FEBRUARY 2024 AND 2026 MEETINGS AT THE HOTEL GALVEZ IN GALVESTON, TX. IT SEEKS TO BUILD ON THE PREVIOUS SUCCESSES OF THE ALCOHOL AND THE NERVOUS SYSTEM GRCS AS THIS MEETING HAS BECOME CRITICAL FOR BUDDING BASIC AND TRANSLATIONAL ALCOHOL RESEARCHERS. IT ALSO PROVIDES A FORUM FOR INTERACTIONS BETWEEN TRAINEES, EARLY CAREER AND SENIOR AND ESTABLISHED SCIENTISTS AND ONE THAT IS HIGHLY VALUABLE FOR EXCHANGE OF NEW IDEA AND CONCEPTS. THE MAIN GOAL OF THIS MEETING IS TO PROMOTE MEANINGFUL DISCUSSION OF RESEARCH DEVELOPMENTS, BUILD NEW SCIENTIFIC COLLABORATIONS, AND MOVE FORWARD THE NEXT GENERATION OF SCIENTIFIC ADVANCES IN ALCOHOL NEUROSCIENCE RESEARCH. ANOTHER GOAL IS TO INTEGRATE PRECLINICAL AND CLINICAL ALCOHOL RESEARCH ACROSS MULTIPLE DOMAINS TO FURTHER ENRICH THE ADVANCEMENT OF KNOWLEDGE REGARDING TRANSLATIONAL AND CLINICAL NEUROSCIENCE OF ALCOHOL. TO ACCOMPLISH THESE GOALS, WE PROPOSE: 1) TO PROVIDE A FORUM TO PROMOTE OPEN DISCUSSION OF CUTTING-EDGE RESEARCH AT THE FOREFRONT OF ALCOHOL EFFECTS ON THE NERVOUS SYSTEM AND RELATED NEUROSCIENCE AREAS; 2) TO INTRODUCE BREAKTHROUGH NEUROSCIENCE APPROACHES THAT FACILITATE THE UNDERSTANDING OF BRAIN MECHANISMS DRIVING ALCOHOL DRINKING AND ALCOHOL MISUSE AS WELL AS MECHANISMS INVOLVED IN THE PATHOPHYSIOLOGY OF ALCOHOL EXPOSURE DURING DEVELOPMENT; 3) TO PROMOTE INTERACTION BETWEEN YOUNG AND SENIOR INVESTIGATORS AND EXCHANGE OF IDEAS THAT SHAPE THE FUTURE DIRECTIONS OF THE ALCOHOL NEUROSCIENCE COMMUNITY; 4) TO FOSTER DEVELOPMENT OF THE NEXT GENERATION OF DIVERSE GROUP OF ALCOHOL RESEARCHERS BY ENCOURAGING THE PARTICIPATION OF STUDENTS AND POSTDOCTORAL FELLOWS BOTH IN THE ALCOHOL AND ITS RELATED RESEARCH FIELDS. THIS CONFERENCE WILL FOCUS ON PRESENTATION OF CUTTING-EDGE UNPUBLISHED SCIENCE THAT IS AT THE FOREFRONT OF THE FIELD. THE UNIQUE STRUCTURE OF THE MEETING INTEGRATES AND ENCOURAGES DISCUSSION WITHIN THE SESSIONS AND PROVIDES AMPLE OPPORTUNITIES FOR EXCHANGE OF IDEAS AT THE POSTER SESSIONS AND DURING SHARED MEAL TIMES. THIS R13 IS IMPORTANT AS IT WILL ALLOW SUPPORT OF THE REGISTRATION FEES AND/OR TRAVEL SUPPORT FOR PARTICIPANTS, INCLUDING, JUNIOR INVESTIGATORS, POSTDOCTORAL FELLOWS AND/OR GRADUATE STUDENTS FOR THE GRC AND THE ASSOCIATED GRS. HISTORICALLY, THIS APPROACH ALLOWED FOR A HIGH LEVEL OF PARTICIPATION FROM TRAINEES MAKING THIS CONFERENCE AN OUTSTANDING NETWORKING OPPORTUNITY THAT IS OF GREAT VALUE TO CAREER DEVELOPMENT. THE INCLUSION OF A DIVERSE GROUP OF TRAINEES AND THE ESTABLISHMENT OF AN ENVIRONMENT THAT WELCOMES FREE EXCHANGE OF IDEAS ADDS TREMENDOUS VALUE TO THE ENVIRONMENT OF THIS DYNAMIC CONFERENCE. THIS GRC FILLS A CRITICAL NEED FOR A CONTINUING MEETING THAT UNIQUELY SHARES ALCOHOL NEUROSCIENCE RESEARCH AT THE FOREFRONT OF THE FIELD BY RENOWNED ALCOHOL RESEARCHERS AND THOSE THAT ARE STARTING THEIR ALCOHOL RESEARCH CAREERS. WE ENVISION THE GRC AND ASSOCIATED GRS TO SIGNIFICANTLY ADVANCE OUR UNDERSTANDING OF THE NEUROSCIENCE OF ALCOHOL ADDICTION WITHIN A FRAMEWORK INTENDED TO HAVE IMPLICATIONS AND CONSIDERATIONS FOR THE TREATMENT OF ALCOHOL USE DISORDER.

CONFERENCE: 2025 CARBON CAPTURE, UTILIZATION AND STORAGE GRC/GRS -THE GORDON RESEARCH CONFERENCE ON CARBON CAPTURE, UTILIZATION AND STORAGE (GRC-CCUS) IS ORGANIZED TO EXPLORE AND DISSEMINATE EMERGING ADVANCES WITH RESPECT TO CREATING SUSTAINABLE CARBON MANAGEMENT SOLUTIONS. THIS CONFERENCE ADDRESSES THE URGENT ECOLOGICAL AND ENVIRONMENTAL NEED TO ADVANCE SUSTAINABLE CARBON MANAGEMENT SOLUTIONS TO MEET THE GROWING NEED FOR ENERGY AND RESOURCES WHILE LIMITING DETRIMENTAL ENVIRONMENTAL IMPACTS. THE CONFERENCE IS FORWARD ? LOOKING AND IS ORGANIZED TO DISSEMINATE EMERGING ADVANCES IN HARNESSING NATURAL RESOURCES INCLUDING SOIL, WATER, AND BIOMASS TO AID IN CARBON MANAGEMENT. THE CONFERENCE PROVIDES A PLATFORM TO EDUCATE SCIENTISTS AND ENGINEERS ACROSS THE CAREER PIPELINE ON THE LATEST ADVANCES IN ENGINEERED AND NATURAL SOLUTIONS TO CAPTURE, CONVERT, STORE, AND REMOVE CO2 EMISSIONS FOR A SUSTAINABLE FUTURE. THE CONFERENCE SERVES AS PLATFORM TO DISCUSS EMERGING SCIENTIFIC AND TECHNOLOGICAL ADVANCES FOR MANAGING RISING CO2 EMISSIONS. TOPICS RANGING FROM THE FUNDAMENTALS OF CARBON TRANSFORMATIONS TO THE ROLE OF BIOMASS, SOIL, AND WATER RESOURCES IN CARBON MANAGEMENT, INDUSTRIAL DECARBONIZATION, AND SCALE ? UP AND DEPLOYMENT WILL BE DISCUSSED. THE CONFERENCE IS DESIGNED TO BROADEN PARTICIPATION OF A WIDE RANGE OF STAKEHOLDERS IN ADVANCING AND CO-CREATING TRANSFORMATIVE CARBON MANAGEMENT SOLUTIONS. THESE STAKEHOLDERS INCLUDE STUDENTS, EARLY CAREER RESEARCHERS, FACULTY MEMBERS, INDUSTRY AND NATIONAL LABORATORY REPRESENTATIVES. INTERNATIONAL ENGAGEMENT AND COLLABORATIONS WILL BE FOSTERED TO EDUCATE AND TRAIN THE NEXT GENERATION OF LEADERS IN ADVANCING SUSTAINABLE ENGINEERED AND NATURAL CARBON MANAGEMENT SOLUTIONS. EARLY CAREER RESEARCHERS WILL HAVE THE OPPORTUNITY TO DISSEMINATE THEIR FINDINGS, AND SEEK TRAINING AND MENTORING THROUGH THE GORDON RESEARCH SEMINAR (GRS). NEW SCIENTIFIC AND TECHNOLOGICAL INSIGHTS FROM SCALING UP SOLUTIONS WILL INFORM THE COMMUNITY ON OPPORTUNITIES AND CHALLENGES IN UNLOCKING THE PATH TO COMMERCIAL IMPACT. NEW KNOWLEDGE ASSOCIATED WITH SOCIAL ACCEPTANCE AND GOVERNANCE OF CARBON MANAGEMENT SOLUTIONS WILL BE SHARED AT THIS CONFERENCE. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

CONFERENCE: INTERIOR OF THE EARTH GORDON RESEARCH CONFERENCE AND SEMINAR -THIS AWARD WILL PARTIALLY SUPPORT THE 2023 INTERIOR OF THE EARTH GORDON RESEARCH CONFERENCE (GRC). THIS GRC WILL BE THE 13TH IN A SERIES OF INTERIOR OF THE EARTH CONFERENCES THAT FOCUS ON THE STRUCTURE, DYNAMICS, AND EVOLUTION OF THE EARTH?S INTERIOR. THIS MEETING WILL BRING TOGETHER SCIENTISTS FROM A WIDE RANGE OF SUBDISCIPLINES WITHIN EARTH SCIENCES, INCLUDING GEOCHEMISTRY, GEODYNAMICS, MINERAL PHYSICS, ROCK DEFORMATION, SEISMOLOGY, AND PETROLOGY. WE HAVE REQUESTED FUNDS TO HELP SUPPORT TRAVEL COSTS OF EARLY-CAREER CONFERENCE PARTICIPANTS (GRADUATE STUDENTS, POSTDOCTORAL SCIENTISTS, AND EARLY-CAREER FACULTY). THE GRC WILL TAKE PLACE AT MOUNT HOLYOKE COLLEGE IN SOUTH HADLEY, MASSACHUSETTS FROM JUNE 18-23, 2023 AND WILL BE HELD IN CONJUNCTION WITH A GORDON RESEARCH SEMINAR (GRS) FROM JUNE 17-18 AT THE SAME VENUE. THE GRS IS AIMED AT AN AUDIENCE OF GRADUATE STUDENTS AND POSTDOCTORAL SCHOLARS AND PROVIDES A UNIQUE ENVIRONMENT FOR THESE EARLY-CAREER SCIENTISTS TO PRESENT AND EXCHANGE STATE OF THE ART IDEAS AND RESULTS. THE TRAVEL SUPPORT PROVIDED BY THIS AWARD WILL HELP TO FUND CONFERENCE ATTENDANCE FOR EARLY-CAREER SCIENTISTS TO ATTEND THE GRS AND/OR THE GRC. THE THEME OF THE 2023 GRC IS ?MATERIAL PROPERTIES OF THE MANTLE AND CORE AND THEIR CONSTRAINTS, CAUSES AND CONSEQUENCES FOR EARTH EVOLUTION.? THIS THEME WILL ENGAGE SCIENTISTS WHO WORK ON A RANGE OF DEPTHS WITHIN THE EARTH, FROM THE LITHOSPHERIC MANTLE TO THE CORE, AND WILL ENABLE DISCUSSION ON THE STRUCTURE AND DYNAMICS OF THE EARTH?S INTERIOR THROUGH THE PRISM OF THE PROPERTIES OF THE MATERIALS THAT MAKE UP ITS MANTLE AND CORE. UNDERSTANDING THESE PROPERTIES ? FOR EXAMPLE, RHEOLOGY, COMPOSITION, ELASTICITY, AND THERMAL BEHAVIOR ? IS KEY FOR UNDERSTANDING THE INNER WORKINGS OF OUR PLANET. THE CONFERENCE WILL ENCOMPASS KEYNOTE TALKS THAT EMPHASIZE NEW (UNPUBLISHED RESULTS) AS WELL AS POSTER PRESENTATIONS, WHICH WILL PROVIDE THE OPPORTUNITY FOR PARTICIPANTS (PARTICULARLY EARLY-CAREER SCIENTISTS) TO PRESENT THEIR WORK IN POSTER FORMAT. NETWORKING BY YOUNGER SCIENTISTS WILL BE GREATLY FACILITATED BY THE PRECEDING GRS, WHICH HAS THE THEME ?EVOLUTION OF THE INTERIOR STRUCTURE OF EARTH FROM THE MAGMA OCEAN STAGE TO THE PRESENT.? IN CONSTRUCTING THE PROGRAM AND IN ADVERTISING FOR THE MEETING, WE HAVE BEEN CONSCIOUS OF DIVERSITY ALONG A NUMBER OF DIMENSIONS. WE HAVE PLACED PARTICULAR EMPHASIS ON GIVING SPEAKING OPPORTUNITIES TO EARLY-CAREER SCIENTISTS; HAVING A SIGNIFICANT PROPORTION OF EARLY-CAREER RESEARCHERS AND FIRST-TIME ATTENDEES AS KEYNOTE SPEAKERS AND DISCUSSION LEADERS WILL ENCOURAGE GREATER PARTICIPATION ACROSS THE GLOBAL COMMUNITY OF DEEP EARTH RESEARCHERS. THE PRECEDING GRS MEETING WILL INCLUDE A MENTORSHIP SESSION THAT FOCUSES ON COMMUNICATION AND CAREERS IN EARTH SCIENCE. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

CONFERENCE: 2025 COASTAL OCEAN DYNAMICS GRC/GRS -THE GORDON RESEARCH CONFERENCES ORGANIZATION HAS A LONG HISTORY OF PROVIDING A FORUM FOR THE PRESENTATION AND DISCUSSION OF CUTTING-EDGE RESEARCH IN A VARIETY OF SCIENCE AND ENGINEERING FIELDS, INCLUDING IN COASTAL OCEAN DYNAMICS. THIS GRANT WILL PROVIDE A PARTIAL CONTRIBUTION TOWARD ATTENDEE COSTS FOR THE GORDON RESEARCH SEMINAR (GRS) AND GORDON RESEARCH CONFERENCE (GRC) ON COASTAL OCEAN DYNAMICS TO BE HELD AT COLBY-SAWYER COLLEGE IN NEW LONDON, NEW HAMPSHIRE, FROM JUNE 7?8 AND 8?13, 2025, RESPECTIVELY. THIS GRC, CONVENED EVERY TWO YEARS, BRINGS TOGETHER ACADEMIC AND FEDERAL RESEARCHERS TO SHARE THE LATEST ADVANCES AND IDENTIFY NEW CHALLENGES IN COASTAL PHYSICAL OCEANOGRAPHY AND RELATED DYNAMICS. NSF HAS A LONG TRACK RECORD OF SUPPORTING ATTENDEE PARTICIPATION IN THIS GRC AND THE FUNDS WILL BE USED TO SUPPORT THE ATTENDANCE OF US BASED STUDENTS, POSTDOCS, OTHER EARLY CAREER RESEARCHERS, INVITED SPEAKERS AND DISCUSSION LEADERS, AND OTHER MID-CAREER AND SENIOR RESEARCHERS SERVING AS MENTORS. THIS GRC AND GRS SUPPORT SCIENTIFIC ADVANCEMENT AND WORKFORCE DEVELOPMENT THAT SUPPORT SOCIETAL WELL-BEING. COASTAL OCEANS PLAY IMPORTANT ROLES IN THE EARTH SYSTEM, FOR EXAMPLE BY TRANSFORMING FRESHWATER DISCHARGES FROM LAND AND BY DISSIPATING TIDAL ENERGY. UNDERSTANDING PHYSICAL OCEANOGRAPHIC AND RELATED PROCESSES OCCURRING IN COASTAL OCEANS IS NECESSARY TO LINK OCEAN OBSERVATIONS, MODELS, AND PREDICTIONS TO SOCIETAL NEEDS. BY FOSTERING COLLABORATION AMONG EXPERTS AND MENTORING OF EARLY-CAREER SCIENTISTS, THE CONFERENCE DRIVES INNOVATIONS IN OCEAN MODELING, OBSERVATION, AND PREDICTION, IMPROVING OUR UNDERSTANDING OF COASTAL SYSTEMS, CONTRIBUTING TO DISASTER PREPAREDNESS AND RESOURCE MANAGEMENT, AND BENEFITING COASTAL COMMUNITIES. THE GRC CHAIRS AND VICE-CHAIRS, ELECTED BY ATTENDEES AT PREVIOUS GRCS, HAVE DESIGNED THE PROGRAMS FOR THE 2025 GRC AND GRS ON COASTAL OCEAN DYNAMICS TO FACILITATE INTELLECTUAL EXCHANGES BETWEEN RESEARCHERS WORKING IN COMPLEMENTARY AREAS OF COASTAL PHYSICAL OCEANOGRAPHY AND LEAD TO NEW COLLABORATIONS. THE GRC PLENARY TALKS, GIVEN BY INVITED SPEAKERS SELECTED BY THE PROGRAM COMMITTEE, WILL COVER TOPICS INCLUDING COASTAL OCEAN PREDICTION, NOVEL OBSERVING TECHNIQUES, AND MACHINE LEARNING. SCHEDULED SESSION TOPICS ARE: COASTAL EXTREMES, LOW-LATITUDE REGIONS, OCEAN ? COASTAL SEAS INTERACTIONS, MID-LATITUDE REGIONS, PHYSICAL-BIOGEOCHEMICAL PROCESSES, HIGH-LATITUDE REGIONS, OBSERVING AND PREDICTING MULTI-SCALE DYNAMICS IN THE OCEAN, THE GLOBAL COASTAL OCEAN, AND TECHNIQUES AND TECHNOLOGIES FOR COASTAL OCEANS. THE POSTER SESSIONS ARE OPEN TO PRESENTATIONS ON ANY COASTAL PHYSICAL OCEANOGRAPHIC OR RELATED TOPIC. DISCUSSION LEADERS HAVE BEEN RECRUITED TO STIMULATE AND MODERATE DISCUSSION AFTER EACH SESSION. AS SESSION CHAIRS, THE DISCUSSION LEADERS WORK IN ADVANCE WITH THE SPEAKERS TO ENSURE PRESENTATIONS ADDRESS NEW, THOUGHT-PROVOKING MATERIAL AND MINIMIZE REVIEW OF EXISTING WORK. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

2017 GORDON RESEARCH CONFERENCE ON CATCHMENT SCIENCE: INTERACTIONS OF HYDROLOGY, BIOLOGY & GEOCHEMISTRY

CONFERENCE: 2026 GRANULAR MATTER GORDON RESEARCH CONFERENCE AND SEMINAR -THIS AWARD SUPPORTS U.S.-BASED SCIENTISTS IN ATTENDING THE 2026 GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR ON GRANULAR MATTER. GRANULAR MATTER ENCOMPASSES ANY SYSTEM WITH DISCRETE PARTICLES AS A SUBSTANTIAL COMPONENT. THIS INCLUDES MATERIALS LIKE SAND, SOIL, MUD, AND ALGAL BLOOMS. THE CONFERENCE MEETINGS WILL ACCELERATE UNDERSTANDING OF GRANULAR MATERIALS ACROSS DISCIPLINES, INCLUDING GEOSCIENCES, PHYSICS, MATERIALS SCIENCE, ENGINEERING, MATHEMATICS, AND BIOLOGY. GRANULAR MATTER RESEARCH HAS PRACTICAL IMPORTANCE, SUCH AS FOR LANDSLIDE PREDICTION AND INDUSTRIAL PROCESSES. CONFERENCE SESSIONS WILL ADDRESS THE PHYSICS OF GRANULAR MATTER, GRAINS IN THE NATURAL WORLD (SAND, SNOW), BIOLOGICAL MATERIALS, ARTIFICIAL INTELLIGENCE, MANUFACTURING, AND MORE. THESE TOPICS WILL DRAW ATTENDEES AND SPEAKERS FROM ACADEMIA, INDUSTRY, AND GOVERNMENT LABS. THE MEETING FORMAT WILL EMPHASIZE PRESENTATION OF NEW, UNPUBLISHED WORK, FOLLOWED BY OPEN DISCUSSION. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

UNDERGRADUATE BIOLOGY EDUCATION RESEARCH GORDON RESEARCH CONFERENCE PROPOSAL: ACHIEVING WIDESPREAD IMPROVEMENT IN UNDERGRADUATE EDUCATION

2019 CATCHMENT SCIENCE IN THE AGE OF BIG DATA GRC/GRS, ANDOVER, NH, JUNE 23-28, 2019

2026 GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR ON MULTIFUNCTIONAL MATERIALS AND STRUCTURES; VENTURA, CALIFORNIA; 25-30 JANUARY 2026 -THIS AWARD WILL SUPPORT THE 2026 GORDON RESEARCH CONFERENCE (GRC) ON MULTIFUNCTIONAL MATERIALS AND STRUCTURES, FOCUSED ON THE THEME ENABLING MULTIFUNCTIONALITY THROUGH AI-INFORMED MATERIAL DISCOVERY AND SYSTEM DESIGN, ALONG WITH THE ACCOMPANYING GORDON RESEARCH SEMINAR (GRS) TAILORED FOR GRADUATE STUDENTS, POSTDOCTORAL SCHOLARS, AND JUNIOR RESEARCHERS. THE EVENTS ARE CO-LOCATED, WITH THE GRS SCHEDULED FOR 24-25 JANUARY 2026, FOLLOWED BY THE GRC FROM 25-30 JANUARY 2026. THE CONFERENCE WILL BRING TOGETHER RESEARCHERS AND PRACTITIONERS FROM ACROSS ACADEMIA, INDUSTRY, AND GOVERNMENT TO EXCHANGE INSIGHTS, SHARE RECENT ADVANCES, AND STRENGTHEN INTERDISCIPLINARY COLLABORATION IN EMERGING AREAS OF MULTIFUNCTIONAL MATERIALS RESEARCH. SUPPORT PROVIDED THROUGH THIS AWARD WILL ENABLE EARLY-CAREER RESEARCHERS TO ATTEND AND PARTICIPATE IN BOTH EVENTS, ENHANCING TECHNICAL DIALOGUE AND SCIENTIFIC EXCHANGE WITHIN THE FIELD. OUTCOMES ARE EXPECTED TO INCLUDE NEW APPROACHES TO INTEGRATING INTELLIGENT MATERIALS SYSTEMS WITH COMPUTATIONAL DESIGN AND MACHINE LEARNING TOOLS, AS WELL AS COLLABORATIVE EFFORTS THAT DRIVE INNOVATION ACROSS DISCIPLINES. THE CONFERENCE AND SEMINAR WILL EXPLORE SCIENTIFIC CHALLENGES CENTRAL TO MULTIFUNCTIONAL MATERIALS AND STRUCTURES THAT EXHIBIT ADAPTABLE, ACTIVE, AND RECONFIGURABLE BEHAVIOR. TECHNICAL FOCUS AREAS INCLUDE: (A) INFORMATICS-DRIVEN DISCOVERY OF MATERIALS AND STRUCTURES, (B) DATA-GUIDED MODELING AND INTEGRATED SYSTEM DESIGN, (C) DEVELOPMENT OF INTELLIGENT AND PROGRAMMABLE MATERIALS, (D) RESEARCH INTO SYNTHETIC AND BIO-INTEGRATED MATERIAL SYSTEMS, AND (E) ADVANCING MULTIFUNCTIONAL TECHNOLOGIES TO HIGHER TECHNICAL READINESS LEVELS. THE MEETINGS WILL DRAW A WIDE RANGE OF RESEARCHERS WITH EXPERTISE IN MECHANICS, MATERIALS SCIENCE, CHEMISTRY, PHYSICS, COMPUTATIONAL ENGINEERING, AND SYSTEM DESIGN. DISCUSSIONS WILL TARGET KEY ISSUES IN THE FIELD AND FOSTER ACTIONABLE IDEAS TO PROPEL PROGRESS IN ENGINEERING MULTIFUNCTIONALITY FOR REAL-WORLD APPLICATIONS IN ENERGY, SAFETY, SUSTAINABILITY, AND ADVANCED MANUFACTURING. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

CONFERENCE: 2024 GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR ON MULTIFUNCTIONAL MATERIALS AND STRUCTURES; VENTURA, CALIFORNIA; JANUARY 27-FEBRUARY 2, 2024 -THIS AWARD WILL SUPPORT THE 2024 GORDON RESEARCH CONFERENCE (GRC) ON MULTIFUNCTIONAL MATERIALS AND STRUCTURES ON THE THEME OF DISCOVERY OF RECONFIGURABLE, HYBRID AND SUSTAINABLE MATERIALS AND THE ACCOMPANYING GORDON RESEARCH SEMINAR (GRS) ON THE THEME OF MORPHOLOGY AND HIERARCHY IN MULTIFUNCTIONAL MATERIALS DESIGN. THE GRC WILL BE HELD IN VENTURA, CALIFORNIA, ON JANUARY 28 ? FEBRUARY 2, 2024, PRECEDED BY THE INAUGURAL GRS THAT WILL TAKE PLACE AT THE SAME LOCATION ON JANUARY 27 ? 28, 2024. THE GRC ON MULTIFUNCTIONAL MATERIALS AND STRUCTURES IS A LEADING TECHNICAL FORUM ON THE LATEST DEVELOPMENTS IN THE FIELD, BRINGING TOGETHER A DIVERSE GROUP OF RESEARCHERS TO DISCUSS RECENT ADVANCES AND UNPUBLISHED RESEARCH, SPAWN NEW IDEAS, AND FOSTER PRODUCTIVE INTERDISCIPLINARY COLLABORATIONS. THE INAUGURAL GRS WILL BE ORGANIZED AND ATTENDED EXCLUSIVELY BY GRADUATE STUDENTS, POST-DOCTORAL SCHOLARS, AND JUNIOR RESEARCHERS. FUNDING THROUGH THIS AWARD WILL INCREASE THE NUMBER OF GRADUATE STUDENT AND POST-DOCTORAL SCHOLAR PARTICIPANTS TO PREPARE THE NEXT GENERATION OF SCIENTIFIC LEADERS IN THIS FIELD. THE POTENTIAL SOCIETAL BENEFITS AND IMPACT OF MULTIFUNCTIONALITY INCLUDE MATERIALS SUSTAINABILITY AND ENERGY RESOURCE MANAGEMENT THROUGH LIFETIME EXTENSIONS OF ENGINEERED COMPONENTS THAT ARE ENABLED BY NEW MULTIFUNCTIONAL RESPONSE, EMBEDDED END-OF-LIFE FUNCTIONALITIES, SAFER SYSTEMS THROUGH ADAPTIVE AND SELF-AWARENESS CAPABILITIES AND IMPROVED ENERGY EFFICIENCY. THE CONFERENCE OUTCOMES ARE EXPECTED TO INCLUDE NOVEL CONCEPTS AND MECHANISMS FOR ACHIEVING HYBRID MULTIFUNCTIONAL MATERIALS NOT POSSIBLE BEFORE, AS WELL AS NEW COLLABORATIONS AND WAYS OF COLLABORATING ACROSS DISCIPLINES. THIS CONFERENCE AND THE ADJACENT SEMINAR SEEK TO ADDRESS FUNDAMENTAL SCIENTIFIC ISSUES ASSOCIATED WITH (A) MATERIAL AND STRUCTURAL MULTIFUNCTIONALITY, SHAPE RECONFIGURABILITY AND ADAPTIVITY, (B) DISCOVERY AND SYNTHESIS OF HYBRID MULTIFUNCTIONAL MATERIALS THROUGH THEORY AND RECENT DEVELOPMENTS IN MACHINE LEARNING AND DATA SCIENCES, (C) COMPUTABLE AND IRREGULAR MATERIALS AND MATERIALS FAR FROM EQUILIBRIUM, (D) LIVING ENGINEERING MATERIAL SYSTEMS AND ACTIVE MATTER, AND (E) HYBRID, SOLID-LIQUID MULTIFUNCTIONAL MATERIALS AND MATERIAL REGENERATION AND SUSTAINABILITY. THE CONFERENCE WILL PRESENT KEY SCIENTIFIC ISSUES AND BOTTLENECKS IN MAKING MAJOR ADVANCES IN THESE INNOVATIVE RESEARCH AREAS, WITH PROSPECTIVE IMPACTS TO A BROAD RANGE OF APPLICATIONS. RESEARCHERS FROM A VIBRANT INTERNATIONAL COMMUNITY OF SCIENTISTS AND ENGINEERS, AND A WIDE RANGE OF DISCIPLINES ENCOMPASSING PHYSICS, MECHANICS, MATERIALS SCIENCE, ENGINEERING SCIENCE, CHEMISTRY, BIOLOGY, MATHEMATICS, AND COMPUTATIONAL SCIENCE AND ENGINEERING, WILL ADDRESS THE ISSUES ASSOCIATED WITH ENVISIONING, DESIGNING, AND CREATING SYNTHETIC MULTIFUNCTIONAL MATERIALS AND STRUCTURES. THEY WILL IDENTIFY GAPS AND PRESENT POTENTIAL SOLUTIONS ON THE INTEGRATION OF NOVEL FUNCTIONALITIES INTO ENGINEERING MATERIAL SYSTEMS AND STRUCTURES. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

WE REQUEST NASA FUNDS TO HELP SUPPORT THE 2019 GORDON RESEARCH CONFERENCE (GRC) ON ORIGINS OF SOLAR SYSTEMS. THIS HIGHLY INTERDISCIPLINARY BIENNIAL MEETING BRINGS TOGETHER RESEARCHERS FROM DIVERSE COMMUNITIES (ASTRONOMY COSMOCHEMISTRY PLANETARY SCIENCE) TO DISCUSS CUTTING-EDGE PROBLEMS REGARDING THE ORIGIN AND EVOLUTION OF PLANETARY SYSTEMS (OUR OWN SOLAR SYSTEM AND EXOPLANETS). THE 2019 CONFERENCE HAS THE THEME METEORITICAL SPACECRAFT AND ASTROPHYSICAL PERSPECTIVES ON THE ASSEMBLY AND COMPOSITION OF PLANETS. THERE WILL BE CONSIDERABLE FOCUS ON EXCITING RECENT RESULTS FROM BOTH STATE-OF-THE-ART ASTRONOMICAL FACILITIES (E.G. THE ATACAMA LARGE MILLIMETER ARRAY ALMA) AND SPACECRAFT (E.G. NEW HORIZONS OSIRIS-REX HAYABUSA2 TESS). IMMEDIATELY PRECEDING THE GRC THIS YEAR WILL BE AN ASSOCIATED GORDON RESEARCH SEMINAR (GRS) SUBTITLED THE COMPOSITION AND ASSEMBLY OF PLANETS. THE GRS IS A POSTDOC-ORGANIZED TWO-DAY SEMINAR FOR YOUNG SCIENTISTS I.E. GRADUATE STUDENTS AND POSTDOCS. IT IS AIMED AT PROVIDE A UNIQUE FORUM FOR YOUNG SCIENTISTS TO PRESENT NEW DATA AND EXCHANGE INNOVATIVE IDEAS ACROSS THE FIELDS REPRESENTED BY THE GRC AND PROVIDE THE EARLY CAREER PARTICIPANTS WITH THE BACKGROUND INFORMATION NEEDED TO GET THE MOST OUT OF THE GRC. THE ORIGINS GRC IS DIRECTLY RELEVANT TO NASA S 2018 STRATEGIC PLAN IN PARTICULAR STRATEGIC OBJECTIVE 1.1. MOREOVER ITS GOALS ARE COMMENSURATE WITH AND RELEVANT TO THE GOALS OF THE EMERGING WORLDS HABITABLE WORLDS AND EXOPLANETS RESEARCH PROGRAMS AS WELL AS TO THE AFOREMENTIONED ONGOING NASA MISSIONS. NASA FUNDING FOR THIS CONFERENCE SUPPORTS THE PARTICIPATION OF PIS IN A MEETING THAT IS VECTORED EXACTLY TOWARD THE GOALS OF THESE PROGRAMS PROVIDING MAXIMUM BENEFIT TO NASA FOR THE TRAVEL COSTS REQUIRED AND ALSO GREATLY ENABLES EARLY CAREER SCIENTISTS TO ATTEND HELPING TO MOLD THE NEXT GENERATION OF INTERDISCIPLINARY RESEARCHERS.

2018 PHYSICS RESEARCH AND EDUCATION GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SYMPOSIUM

CONFERENCE: 2025 ATMOSPHERIC CHEMISTRY GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR -THIS PROJECT SUPPORTS THE 2025 GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR ON ATMOSPHERIC CHEMISTRY. THE THEME OF THE CONFERENCE IS ?UNDERSTANDING THE ATMOSPHERE VIA MOLECULAR PROCESSES AND GLOBAL IMPACTS.? THIS CONFERENCE BRINGS TOGETHER RESEARCHERS FROM UNIVERSITIES, GOVERNMENT LABORATORIES, AND PRIVATE RESEARCH INSTITUTES, TO PROMOTE THE DISCUSSION OF INFORMATION AND IDEAS ON TOPICS OF CONTEMPORARY INTEREST IN ATMOSPHERIC CHEMISTRY. THE CONFERENCE CONCENTRATES ON THE LATEST DEVELOPMENTS IN THE FIELD, INCLUDING THE FUNDAMENTAL UNDERSTANDING OF CHEMICAL PROCESSES FROM THE MOLECULAR LEVEL TO GLOBAL IMPACTS ON EARTH AND SPACE. THE INTELLECTUAL MERIT OF THIS SYMPOSIUM LIES IN BRINGING TOGETHER LEADERS AND SCHOLARS COVERING A BROAD RANGE OF RESEARCH IN THE FIELD OF ATMOSPHERIC CHEMISTRY, INCLUDING RESEARCH ON THE SOURCES, SINKS, TRANSPORT, TRANSFORMATION AND IMPACTS OF GASES AND AEROSOLS IN THE ATMOSPHERE THROUGH MODELS, OBSERVATIONS, AND EXPERIMENTS. THIS CONFERENCE WILL HAVE SESSIONS ON THE FOLLOWING TOPICS: ATMOSPHERIC CHEMISTRY AS A DRIVER AND CONSEQUENCE OF CLIMATE CHANGE, CHEMISTRY IN THE REMOTE AND BIOGENIC ENVIRONMENTS, MULTIPHASE PROCESSES IN ATMOSPHERIC CHEMISTRY, NEW INSIGHTS INTO REACTIVE NITROGEN, PINNING DOWN OUR UNDERSTANDING OF CHEMICAL MECHANISMS, EXPLORING KNOWN AND EMERGING AIR POLLUTANTS, CHALLENGES IN INDOOR AIR CHEMISTRY, FIRES FUELING ATMOSPHERIC CHEMISTRY, AND ATMOSPHERIC COMPOSITION FROM SPACE. THE BROADER IMPACTS OF THE SYMPOSIUM DERIVE FROM THE EXCHANGE OF IDEAS THAT HELP TO FOCUS THE RESEARCH COMMUNITY ON THE MOST PRESSING QUESTIONS IN ATMOSPHERIC CHEMISTRY. YOUNG SCIENTISTS ARE INVITED TO THE GORDON RESEARCH SEMINAR THAT IMMEDIATELY PRECEDES THE CONFERENCE. THE GORDON RESEARCH SEMINAR PROVIDES AN OPPORTUNITY FOR YOUNG SCIENTISTS TO MEET, NETWORK, AND EXCHANGE IDEAS WITH LEADERS IN THE ATMOSPHERIC SCIENCES. THE GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR ON ATMOSPHERIC CHEMISTRY CREATE A BROAD INTELLECTUAL IMPACT ON THE ATMOSPHERIC SCIENTIFIC COMMUNITY. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

GRC ENVIRONMENTAL NANOTECHNOLOGY: PREVENTING AND SOLVING PROBLEMS WITH ENVIRONMENTAL NANOTECHNOLOGY

2017 ENVIRONMENTAL NANOTECHNOLOGY GORDON RESEARCH CONFERENCE AND SEMINAR: A PLATFORM FOR CUTTING EDGE RESEARCH IN NANOTECHNOLOGY APPLICATIONS AND IMPLICATIONS

NEURAL MECHANISMS OF ACOUSTIC COMMUNICATION GORDON RESEARCH CONFERENCE -THIS AWARD WILL PROVIDE SUPPORT TO STUDENTS, POST-DOCTORAL FELLOWS AND JUNIOR SCIENTISTS TO ATTEND THE 2022 GORDON RESEARCH CONFERENCE ON THE NEURAL BASIS OF ACOUSTIC COMMUNICATION (NMAC). DIFFERENT SPECIES OFTEN FEATURE DISTINCT COMMUNICATION STRATEGIES FOR THE PRODUCTION AND PERCEPTION OF ACOUSTIC SOCIAL SIGNALS, AND A COMPARATIVE APPROACH TO THE STUDY OF THE NEURAL MECHANISMS UNDERLYING ACOUSTIC COMMUNICATION CAN LEND INSIGHT INTO GENERAL MECHANISMS OF NEURAL FUNCTION. A MAJOR CHALLENGE IN THE STUDY OF ACOUSTIC COMMUNICATION IS THE SEGREGATION OF INFORMATION BETWEEN HUMAN AND NONHUMAN RESEARCH AS WELL AS THE ISOLATED COMMUNITIES THAT FOCUS ON INDIVIDUAL MODEL SYSTEMS. THE NMAC IS A NEW SCIENTIFIC MEETING CREATED TO BRING TOGETHER A HIGHLY INTERDISCIPLINARY GROUP OF RESEARCHERS TO BETTER UNDERSTAND HOW THE BRAIN ENCODES AND PRODUCES ACOUSTIC SIGNALS. THIS MEETING WILL BRING TOGETHER OUTSTANDING SENIOR AND JUNIOR SCIENTISTS FOR DISCUSSIONS OF THE RECENT ADVANCES IN THE FIELD. THE NMAC CONFERENCE WILL HELP TO REVEAL NEW PRINCIPLES CONCERNING ACOUSTIC COMMUNICATION. TOPICS OF THIS INAUGURAL PROGRAM INCLUDE VOCAL DEVELOPMENT AND LEARNING, VOCAL INTERACTIONS, AUDITORY SPECIALIZATIONS, GENOMICS, PREDICTIVE CODING, AND CORTICAL MECHANISMS OF VOCAL PRODUCTION. THE COMPARATIVE APPROACH THAT IS AT THE HEART OF NEUROETHOLOGY, WILL FACILITATE THE IDENTIFICATION OF COMMON PRINCIPLES OF BRAIN ORGANIZATION AND FUNCTION THAT UNDERLIE ACOUSTIC COMMUNICATION. THE RESULTS PRESENTED AT THE MEETING WILL HAVE THE POTENTIAL TO GUIDE FUTURE DEVELOPMENTS IN MULTIPLE AREAS, INCLUDING NEURAL INSPIRED DESIGN OF ENGINEERED SYSTEMS THAT WILL HAVE CONSIDERABLE SOCIETAL BENEFITS. THE VALUE OF THIS MEETING DERIVES FROM ITS SMALL SIZE, WHICH PROMOTES INTERACTIONS BETWEEN PARTICIPANTS, AND THE ASSEMBLY OF MANY TOP SCIENTISTS WHOSE RESEARCH SPANS NEUROBIOLOGY, ANIMAL BEHAVIOR AND HUMAN CLINICAL DISORDERS. IT SPANS A WIDE VARIETY OF EXPERIMENTAL SYSTEMS AND FOCUSES ON AREAS OF EXCEPTIONAL ACTIVITY OR PROMISE. THIS COMBINATION LEADS TO FRUITFUL COMPARATIVE ANALYSES, RAISES NEW QUESTIONS ABOUT UNDERLYING MECHANISMS AND OFTEN LEADS TO NEW COLLABORATIONS. BY MAXIMIZING BOTH FORMAL DISCUSSION AND INFORMAL INTERACTIONS, THE NMAC WILL HIGHLIGHT EXCITING NEW DEVELOPMENTS IN STUDY OF THE COMMUNICATION PROCESSES THAT ARE ESSENTIAL FOR ANIMAL BEHAVIOR AND ALSO LIE AT THE HEART OF DISORDERS. WITH RESPECT TO BROADER IMPACTS, THIS MEETING WILL BENEFIT THE LARGER COMMUNITY IN MULTIPLE WAYS. FIRST, IT WILL HELP TRAIN AND INSPIRE THE NEXT GENERATION OF SCIENTISTS, BY EXPOSING STUDENTS AND POSTDOCTORAL FELLOWS TO EXCITING SCIENCE AND SCIENTISTS. SECOND, MENTORING SESSIONS, BOTH FORMAL AND INFORMAL, AS WELL AS PROFESSIONAL DEVELOPMENT SESSIONS FOR JUNIOR RESEARCHERS, WILL BE ORGANIZED FOR THE BENEFIT OF JUNIOR RESEARCHERS TO HELP THEM MAKE INFORMED CHOICES ABOUT SCIENTIFIC CAREERS IN ACADEMIA AND BEYOND. FINALLY, A CONCERTED EFFORT WILL BE MADE TO RECRUIT SCIENTISTS FROM UNDER-REPRESENTED GROUPS. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

THE 2017 GORDON RESEARCH CONFERENCE (GRC) ON THE ORIGINS OF SOLAR SYSTEMS WILL BE HELD JUNE 18-JUNE 23 2017. THIS MEETING BRINGS TOGETHER SCIENTISTS FROM THE FIELDS OF ASTRONOMY AND ASTROPHYSICS COSMOCHEMISTRY PLANETARY SCIENCE AND EARTH SCIENCES TO DISCUSS FRONTIER RESEARCH FOCUSED ON UNDERSTANDING THE FORMATION OF PLANETS AND PLANETARY SYSTEMS. THE FOCUS ON THIS YEAR WILL BE UNDER THE SUBTITLE MAKING A HABITABLE PLANET . THIS TOPIC IS WELL SUPPORTED BY NASA S CURRENT SCIENCE FOCUS UNDER NASA S SCIENCE VISION AND PLAN. THE ORIGINS GRC HAS A LONG HISTORY OF FUELING NEW DISCOVERIES AND INSPIRING CROSS-DISCIPLINARY RESEARCH DEDICATED TOWARD THIS GOAL. THIS PROPOSAL REQUESTS FUNDS TO SUPPORT THE MISSION OF BRINGING TOGETHER SCIENTISTS FROM ACROSS MANY DISCIPLINES TO DISCUSS THE LATEST RESEARCH IN THE FIELD OF PLANET FORMATION IDENTIFY INNOVATIVE AVENUES OF EXPLORATION AND EXPOSE INVESTIGATORS TO NEW SUBJECT AREAS. AS AN INNOVATION THIS YEAR WE WILL HOLD A GRADUATE RESEARCH SEMINAR (GRS) DURING THE DAY AND A HALF BEFORE THE CONFERENCE AND A POWER HOUR DURING THE MAIN CONFERENCE. THE GRS IS STUDENT RUN AND WILL INCLUDE TALKS BY PEERS A KEYNOTE BY A SENIOR SPEAKER AND A SESSION ON EARLY CAREER ADVICE. THUS WE EXPECT TO HAVE A GREATER NUMBER OF EARLY CAREER PARTICIPANTS IN THIS YEARS MEETING WITH EXPANDED OPPORTUNITY FOR PARTICIPATING IN THE TRAINING OF THE NEXT GENERATION OF NASA SCIENTISTS.

WORKSHOP: NEUROBIOLOGY OF COGNITION: CIRCUITS, DYNAMICS, ACTION AND PERCEPTION GRC & GRS

2024 NEUROBIOLOGY OF BRAIN DISORDERS GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR - THE SPECIFIC AIMS OF THE 2024 NEUROBIOLOGY OF THE BRAIN DISORDERS GORDON RESEARCH CONFERENCE (GRC) AND THE GORDON RESEARCH SEMINAR (GRS) ARE TO PROMOTE DIALOGUE AMONG ESTABLISHED AND EMERGING LEADERS IN NEURODEGENERATIVE DISEASE. THE CO-CHAIRS, DRS. KAREN DUFF AND CHRIS SHAW, IN CONSULTATION WITH PAST CHAIRS, AND THE 2026 VICE CHAIRS (DRS. HEMALI PHATNANI AND MICHAEL WARD) HAVE PLANNED NINE ORAL SESSIONS THAT WILL FOCUS ON THE CURRENT AND FUTURE LANDSCAPE OF RESEARCH FOR THE MAJOR NEURODEGENERATIVE DISEASES, INCLUDING HOW GENETICS IS INFORMING ON DISEASE MECHANISMS, HOW GENOMICS APPROACHES (INCLUDING BIOINFORMATICS) ARE BEING USED TO ADD MORE MECHANISTIC INSIGHT INTO GENETIC FINDINGS, HOW BIOMARKERS ARE BEING USED TO UNDERSTAND MECHANISMS, DIAGNOSE AND MONITOR DISEASE AND THE STATUS OF THERAPEUTICS, FOR DISEASES, INCLUDING SOME NEW THERAPEUTIC APPROACHES THAT ARE BEING DEVELOPED AND APPLIED TO ADDRESS UNMET NEEDS. IN ADDITION TO THESE SESSIONS THERE BE FOCUSED SESSIONS DISCUSSING THE CURRENT UNDERSTANDING OF ALZHEIMER’S DISEASE AND RELATED DEMENTIAS (AD/ADRD), FTD (INCLUDING TAU AND TDP RELATED DEMENTIAS), PD (INCLUDING LBD) AND ALS, AS WELL AS AGING AND HOW IT IMPACTS THESE DISEASES. THE GRC WILL BE PRECEDED BY A GRS TO FACILITATE THE PRESENTATION AND DISCUSSION OF FRONTIER RESEARCH BY TRAINEES. AS THE CHAIRS AND CO-CHAIRS PLACE THE HIGHEST PRIORITY ON PARTICIPATION BY TRAINEES AND EARLY-CAREER INDIVIDUALS, SHORT TALKS WILL BE SELECTED FROM SUBMITTED ABSTRACTS TO COMPLEMENT INVITED SPEAKERS. WE WILL MAKE EVERY EFFORT TO INCREASE THE PARTICIPATION OF UNDER-REPRESENTED MINORITIES AMONG CONFERENCE PARTICIPANTS AND SPEAKERS. CONFERENCE PARTICIPANTS WILL INTERACT INFORMALLY IN A COLLEGIAL ATMOSPHERE AND HAVE AMPLE FREE TIME, PROVIDING IDEAL SETTINGS FOR PARTICIPANTS TO BRAINSTORM AND ESTABLISH INTERDISCIPLINARY COLLABORATIONS. THE SIGNIFICANCE OF THIS GRC IS TO PROVIDE A UNIQUE FORUM FOR THE INTERNATIONAL COMMUNITY WORKING ON THE NEUROBIOLOGY OF BRAIN DISORDERS, ESPECIALLY AD/ADRD, TO DISCUSS THE LATEST ADVANCES AND THE FUTURE CHALLENGES IN THE FIELD OF NEURODEGENERATION AND AGING-RELATED BRAIN DISORDERS. THE RELEVANCE OF THIS APPLICATION TO PUBLIC HEALTH IS THAT THE DISCUSSIONS WILL DEFINE THE MOST IMPORTANT QUESTIONS FOR AD/ADRD, FTD, PD AND ALS, SPANNING BASIC BIOLOGY AND DISEASE MECHANISMS AND AID THE DEVELOPMENT OF NOVEL THERAPEUTIC STRATEGIES. THE LONG-TERM GOAL OF THIS GRC IS TO PROVIDE A CONSISTENT PLATFORM FOR THIS COMMUNITY TO MEET EVERY TWO YEARS TO DISSEMINATE THE MOST RECENT DISCOVERIES AND FORMULATE THE MOST IMPORTANT QUESTIONS CONCERNING THE CURRENT STATE-OF-THE-ART RESEARCH ON AGE-RELATED NEURODEGENERATIVE DISEASES.

2016 AND 2018 VISUAL SYSTEMS DEVELOPMENT GORDON RESEARCH CONFERENCE & GORDON RESEARCH SEMINAR

CONFERENCE: 2025 GEOCHRONOLOGY GORDON RESEARCH CONFERENCE AND SEMINAR: TIMING, TEMPO AND DRIVERS OF EARTH'S CLIMATE -THIS AWARD SUPPORTS CONFERENCE PARTICIPANTS IN THE 2025 GORDON RESEARCH CONFERENCE ON GEOCHRONOLOGY AND ASSOCIATED GORDON RESEARCH SEMINAR ON GEOCHRONOLOGY. GEOCHRONOLOGY INVOLVES THE DATING OF GEOLOGIC MATERIALS SUCH AS ROCKS, SEDIMENTS AND FOSSILS. THE FIELD OF GEOCHRONOLOGY STRIVES TO QUANTIFY GEOLOGICAL TIME, TO PROVIDE AGE MODELS FOR GEOLOGICAL RECORDS, AND TO CONSTRAIN THE RATES AND DURATIONS OF FUNDAMENTAL GEOLOGICAL PROCESSES AND PHENOMENA. THE PURPOSE OF THIS YEAR?S CONFERENCE IS TO IDENTIFY OPPORTUNITIES AND CHALLENGES FOR FUTURE RESEARCH BY BRINGING TOGETHER GEOCHRONOLOGISTS (RESEARCHERS WHO MEASURE THE AGES OF GEOLOGIC MATERIALS) WITH A BROAD RANGE OF OTHER SCIENTISTS WHOSE RESEARCH RELIES ON APPLICATIONS OF GEOCHRONOLOGY TO IMPROVE UNDERSTANDING OF THE TIMING, TEMPO, AND DRIVERS OF EARTH?S CLIMATE. THE APPLICATION OF GEOCHRONOLOGY TO THE TIMING, TEMPO, AND DRIVERS OF CLIMATE HAS WIDE-RANGING IMPLICATIONS FOR THE RESILIENCE OF LIFE ON OUR PLANET AND GEOCHEMICAL PROCESSES GOVERNING SOLID EARTH-BIOSPHERE INTERACTIONS. BY ENGAGING NEW RESEARCHERS WITHIN THE GEOCHRONOLOGY COMMUNITY, THIS CONFERENCE WILL CONTRIBUTE TO WORKFORCE DEVELOPMENT IN GEOCHRONOLOGY AND ALLIED FIELDS, AS WELL AS PROMOTE BROAD PARTICIPATION IN RESEARCH DIRECTIONS SUPPORTED BY THE NSF DIRECTORATE FOR GEOSCIENCES. THIS AWARD PROVIDES SUPPORT FOR EARLY-CAREER RESEARCHERS AND PARTICIPANTS FROM INSTITUTIONS WITH INSUFFICIENT FUNDS TO ATTEND THE 2025 GORDON RESEARCH CONFERENCE ON GEOCHRONOLOGY FROM AUGUST 17-22, 2025, AND THE COMPANION GORDON RESEARCH SEMINAR ON GEOCHRONOLOGY FROM AUGUST 16-17, 2025, IN SUNDAY RIVER, MAINE. THE CONFERENCE SESSIONS RANGE FROM LONGER TIMESCALES? E.G., PLANETARY HABITABILITY, CLIMATE EXTREMES IN EARTH HISTORY? TO SHORT TIMESCALES, E.G., CLIMATE AND HOMININ EVOLUTION, HUMAN-INDUCED CLIMATE CHANGE, GLACIER AND LANDSCAPE RECORDS OF PAST CLIMATE. THE OVERARCHING GOAL IS TO INFORM GEOCHRONOLOGISTS OF SPECIFIC AREAS IN WHICH FURTHER RESEARCH AND DEVELOPMENT WILL BE MOST FRUITFUL, AND TO INFORM NON-GEOCHRONOLOGISTS OF THE CAPABILITIES AND LIMITATIONS OF THE DIVERSE GEOCHRONOMETERS APPLICABLE TO THEIR RESEARCH PROBLEMS. THIS AWARD IS CO-FUNDED BY PROGRAMS IN THE DIVISIONS OF EARTH SCIENCES (EAR), OCEAN SCIENCES(OCE), AND ATMOSPHERIC AND GEOSPACE (AGS) SCIENCES, AS WELL AS THE OFFICE OF POLAR PROGRAMS (OPP). THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

2017 PHYSICS RESEARCH & EDUCATION: RELATIVITY AND GRAVITATION: CONTEMPORARY RESEARCH AND TEACHING OF EINSTEIN'S PHYSICS GORDON RESEARCH CONFERENCE

GRC-PHYSICS RESEARCH & EDUCATION: THE COMPLEX INTERSECTION OF BIOLOGY AND PHYSICS

CONFERENCE: 2024 MULTISCALE PLANT VASCULAR BIOLOGY GORDON RESEARCH CONFERENCE AND SEMINAR -THIS AWARD SUPPORTS THE ATTENDANCE OF APPROXIMATELY 75 RESEARCH SCIENTISTS, MOSTLY THOSE AT EARLY STAGES OF THEIR CAREER, AT THE GORDON RESEARCH CONFERENCE AND SEMINAR (GRC/GRS) ON MULTISCALE PLANT VASCULAR BIOLOGY, TWO LINKED MEETINGS HELD IN PORTLAND, MAINE, USA FROM JUNE 8-14, 2024. THE GOALS OF THESE MEETING ARE TO (A) SHARE THE MOST CURRENT AND IMPACTFUL RESEARCH IN PLANT VASCULAR BIOLOGY AT A RANGE OF SCALES, WHICH INCLUDES EVERYTHING FROM GENE NETWORKS AND PROTEINS TO GLOBAL CLIMATE CHANGE MODELS; AND (B) BUILD A REPRESENTATIVE, INCLUSIVE AND EQUITABLE SCIENTIFIC COMMUNITY TO ENSURE THAT RESEARCH IN THIS FIELD CONTINUES TO ADVANCE FOR THE BENEFIT OF SOCIETY AS A WHOLE. BECAUSE PLANTS SERVE AS A CRITICAL LINK BETWEEN THE EARTH'S SOILS AND OUR ATMOSPHERE, AN UNDERSTANDING OF PLANT VASCULAR BIOLOGY UNDERPINS SOME OF THE MOST URGENT SOCIETAL AND ENVIRONMENTAL CHALLENGES OF THE 21ST CENTURY. THESE INCLUDE IMPROVED GLOBAL FOOD SECURITY, REDUCED AGRICULTURAL WATER CONSUMPTION, INCREASED BIOENERGY PRODUCTION, ENHANCED CARBON STORAGE IN NATURAL ECOSYSTEMS, AND BIOREMEDIATION (I.E., DECONTAMINATION) OF CONTAMINATED SOILS. THE TWO-DAY GRS THAT PRECEDES THE FULL GRC IS RESTRICTED TO VERY EARLY CAREER SCIENTISTS (I.E., DOCTORAL STUDENTS AND POSTDOCTORAL RESEARCHERS) AND INCLUDES A CAREER MENTORING PANEL. THUS, ONE OF THE PRIMARY EXPECTED OUTCOMES OF THIS CONFERENCE IS TO DEVELOP A MORE DIVERSE (I.E., DEMOGRAPHICALLY-REPRESENTATIVE), INCLUSIVE AND EQUITABLE WORKFORCE IN PLANT BIOLOGY WHO ARE PREPARED PROFESSIONALLY TO TACKLE THESE CHALLENGES. THE OPEN SHARING OF CURRENT SCIENTIFIC RESULTS AT THESE MEETINGS IS EXPECTED TO LEAD TO NEW DIRECTIONS AND PRODUCTIVE COLLABORATIONS. THEMES FOR THE 2024 GRC AND GRS MULTISCALE PLANT VASCULAR BIOLOGY ARE PLANT VASCULATURE AND THE SOIL-PLANT-ATMOSPHERE CONTINUUM AND PLANT RESILIENCE TO STRESS, RESPECTIVELY. THE 2024 GRC PROGRAM INCLUDES 31 SPEAKERS AND DISCUSSION LEADERS ORGANIZED IN SESSIONS ON PLANT VASCULAR DEVELOPMENT; STOMATAL CONTROL AND REGULATION; THE ROLE OF THE ROOT MICROBIOME AND MUTUALISMS ON THE ABILITY OF PLANTS TO TOLERATE ABIOTIC STRESS; COMPUTATIONAL AND IMAGING TECHNIQUES FOR IMPROVED PLANT PHENOTYPING; THE ROLE OF VASCULAR BIOLOGY IN SUSTAINABLE CROPPING SYSTEMS; HYDRAULICS FROM THE RHIZOSPHERE TO LANDSCAPE; PHLOEM TRANSPORT AND WITHIN-PLANT CARBON DYNAMICS; AND PLANT VASCULAR FUNCTION IN A CHANGING CLIMATE. SPECIAL EMPHASES THIS YEAR INCLUDE THE TRANSFER OF CARBON COMPOUNDS AS WELL AS WATER, INCLUDING BIDIRECTIONAL TRANSFER (E.G., INTO THE SOIL VS. SOIL-TO-ATMOSPHERE); THE IMPORTANCE OF THE SOIL-ROOT BIOTIC INTERFACE; AND GREATER REPRESENTATION OF WORK IN AGRICULTURAL AND INTENSIVELY-MANAGED SYSTEMS. GRC/GRS STRUCTURE INCLUDES AMPLE TIME FOR DISCUSSION, ALL OF WHICH OCCURS UNDER AN ?OFF-THE-RECORD? POLICY IN ORDER TO FOSTER THE MOST UP-TO-DATE AND FORWARD-LOOKING EXCHANGE OF IDEAS. IT IS EXPECTED THAT MULTIPLE COLLABORATIONS WILL DEVELOP FROM THESE MEETINGS THAT WILL MEANINGFULLY ADVANCE THE FIELD. COLLECTIVELY, ATTENDEES WILL IDENTIFY THE MOST PRESSING GAPS IN OUR UNDERSTANDING OF PLANT VASCULAR BIOLOGY AND THUS THE HIGHEST PRIORITIES FOR RESEARCH, AS WELL AS THE MOST EFFECTIVE AND PROMISING TECHNIQUES TO ADDRESS THEM. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

2019 INTERIOR OF THE EARTH GRC/GRS

2019 ENVIRONMENTAL NANOTECHNOLOGY GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR

CONFERENCE: 2008 METABOLIC BASIS OF ECOLOGY GRC & GRS: METABOLIC THEORY OF ECOLOGY, TO BE HELD JULY 5-11, 2008 AT THE UNIVERSITY OF NEW ENGLAND.

2025 CORNEA AND OCULAR SURFACE BIOLOGY, PATHOLOGY AND REGENERATION GORDON RESEARCH CONFERENCE - PROJECT SUMMARY THE OCULAR SURFACE IS COMPRISED OF THE CORNEA, CONJUNCTIVA, EYELIDS AND ASSOCIATED GLANDS THAT ARE RESPONSIBLE FOR SECRETION OF THE TEAR FILM. DYSGENESIS OR DISRUPTION OF THE HOMEOSTASIS OF ANY OF THESE STRUCTURES CAN LEAD TO CORNEAL AND OCULAR SURFACE DISEASES, WHICH CAN RESULT IN LOSS OF EYESIGHT OR CAUSE BLINDNESS. UNDERSTANDING THE GENESIS OF THE OCULAR SURFACE TISSUES, AND ITS NORMAL FUNCTION AND REPAIR AFTER DISEASE OR TRAUMA, IS CRUCIAL FOR IDENTIFYING DISEASE-ASSOCIATED GENES AND NOVEL DRUGS THAT MAY LEAD TO INNOVATIVE THERAPIES THAT ARE ESSENTIAL FOR MAINTAINING VISUAL HEALTH. WE REQUEST SUPPORT FOR THE GORDON RESEARCH CONFERENCE AND SEMINAR OF THE CORNEA AND OCULAR SURFACE BIOLOGY, PATHOLOGY AND REGENERATION (GRC-COSBPR), FEBRUARY 16-21, 2025, AT FOUR POINTS SHERATON-HOLIDAY EXPRESS IN VENTURA, CALIFORNIA. THE GOAL OF THE 2025 GRC-COSBPR IS TO BRING TOGETHER INTERNATIONAL LEADERS IN THE FIELD AND PROVIDE A FORUM FOR THE MOST RECENT, CUTTING-EDGE BASIC, TRANSLATIONAL AND CLINICAL RESEARCH FOCUSED ON EXPEDITING TRANSLATION OF FINDINGS FROM BENCH TO BEDSIDE. BUILDING ON THE STRONG TRACK RECORD FROM THE PAST SIX MEETINGS, WE PLAN 9 SCIENTIFIC SESSIONS ON KEY PARADIGM SHIFTING INNOVATIONS IN OCULAR SURFACE BIOLOGY, PATHOLOGY, AND TISSUE REPAIR. THE SESSION TITLES ARE: 1. NOVEL APPROACHES TO DATA ACQUISITION AND ANALYSIS; 2. CELLULAR INTERACTIONS, THE EXTRACELLULAR MATRIX, AND MORPHOGENESIS; 3. GENOMICS AND GENE REGULATION; 4. ADVANCES IN CORNEA AND OCULAR SURFACE WOUND REPAIR; 5. MECHANISMS OF OCULAR SURFACE DISEASE AND DISORDERS; 6. STEM CELLS OF THE OCULAR SURFACE; 7. INFLAMMATION AND REGENERATION OF THE OCULAR SURFACE; 8. SICKNESS AND HEALTH OF THE CORNEA AND OCULAR SURFACE; 9. TRANSLATION OF OCULAR SURFACE RESEARCH INTO NOVEL THERAPIES. WE ARE ORGANIZING A DIVERSE, GENDER-BALANCED MEETING WITH SPEAKERS INVITED FROM NORTH AND LATIN AMERICA, UNITED KINGDOM, ISRAEL, ASIA (JAPAN, INDIA, CHINA), AND AUSTRALIA. SPECIAL EMPHASIS WILL BE GIVEN TO INCREASE DIVERSITY BY INVITING WOMEN AND UNDERREPRESENTED MINORITIES (URMS). EACH SESSION WILL BE CO- MODERATED BY AN EARLY CAREER SCIENTIST PAIRED WITH AN ESTABLISHED RESEARCHER. THE SESSIONS WILL INCLUDE EXTENDED TIME FOR DISCUSSIONS. A PORTION OF EACH SESSION IS UNCOMMITTED TO SELECT SPEAKERS FROM SUBMITTED ABSTRACTS, PARTICULARLY GRADUATE STUDENTS, POSTDOCS, CLINICIAN TRAINEES, EARLY CAREER INVESTIGATORS, AND URMS. THE GRC CONFERENCE WILL INCLUDE A “POWER HOUR” TO DISCUSS CHALLENGES WOMEN AND UNDERREPRESENTED MINORITIES FACE IN SCIENCE AND ISSUES OF DIVERSITY AND INCLUSION. THE 2025 GRC-COSBPR MEETING WILL BE ADVERTISED BY THE GRC AND THE PROGRAM UPDATES WILL BE POSTED ON THE WEBSITE AND VIA SOCIAL MEDIA SUCH AS X (TWITTER) AND FACEBOOK TO INCREASE VISIBILITY AMONG JUNIOR SCIENTISTS AND TRAINEES. WE BELIEVE OUR PROGRAM IS ALIGNED WITH THE SCIENTIFIC GOALS OF NEI AND ITS SUPPORT WILL ENABLE US TO PROVIDE A HIGH QUALITY AND SUCCESSFUL MEETING.

2024 OCEAN MIXING GRC GRS

CONFERENCE: 2023 CHEMISTRY EDUCATION RESEARCH AND PRACTICE GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR -THIS PROJECT SEEKS TO SERVE THE NATIONAL INTEREST BY ADVANCING AND PROPAGATING KNOWLEDGE OF CHEMISTRY TEACHING AND LEARNING AS WELL AS THE APPLICATION OF THIS KNOWLEDGE IN UNDERGRADUATE CHEMISTRY LEARNING ENVIRONMENTS. THE SUMMER 2023 GORDON RESEARCH CONFERENCE (GRC) AND GORDON RESEARCH SEMINAR (GRS) ON CHEMISTRY EDUCATION RESEARCH AND PRACTICE (CERP) WILL FEATURE CUTTING-EDGE CHEMISTRY EDUCATION RESEARCH. THEY WILL BRING RESEARCHERS AND CHEMISTRY TEACHING SCHOLARS TOGETHER TO DISCUSS RECENT METHODS AND FINDINGS AS WELL AS APPLICATIONS OF THE RESEARCH IN INSTRUCTIONAL PRACTICE. THE 2023 CERP GRC BUILDS ON A SUCCESSFUL TRADITION OF GRCS WHILE IT INNOVATES IN THE AREAS OF DIVERSITY, EQUITY, INCLUSION, AND BELONGING. COVID-19 AND RECENT SOCIAL MOVEMENTS HAVE PROMPTED AN INCREASED AMOUNT OF SCHOLARSHIP ON EQUITY, SOCIAL JUSTICE, AND INCLUSION IN CHEMISTRY TEACHING AND LEARNING. THE CONFERENCE ORGANIZERS WILL LEVERAGE THIS NEW SCHOLARSHIP, RECRUIT SPEAKERS AND CONFEREES FROM GROUPS AND INSTITUTIONS THAT HAVE BEEN TRADITIONALLY UNDERREPRESENTED IN THE CHEMICAL SCIENCES, AND HIGHLIGHT A PROGRAMMATIC FOCUS ON DIVERSITY, EQUITY, INCLUSION, AND BELONGING. 2023 ALSO MARKS THE FIRST YEAR OF A CERP GRS CONVENING, WHICH WILL PROVIDE UNIQUE PROFESSIONAL DEVELOPMENT OPPORTUNITIES FOR NEW AND EARLY SCHOLARS WHO CONDUCT CHEMISTRY EDUCATION RESEARCH. THESE SCHOLARS ARE NOT ONLY THE NEXT GENERATION OF CHEMISTRY EDUCATION RESEARCHERS, BUT THEY ARE ALSO AMONG THE NEXT GENERATION OF COLLEGE AND UNIVERSITY FACULTY. BY PARTICIPATING IN THE GRS AND GRC, THEY WILL BUILD THE NECESSARY PROFESSIONAL AND COMMUNAL NETWORKS TO SUPPORT RESEARCH-BASED REFORMS IN CHEMISTRY TEACHING AND LEARNING. FOR THE FIELD OF CHEMISTRY EDUCATION, THE COMBINED 2023 GRC AND GRS ON CERP WILL ADVANCE ACCESS, QUALITY, AND REFORM IN UNDERGRADUATE CHEMISTRY TEACHING AND LEARNING. THE SUMMER 2023 GORDON RESEARCH CONFERENCE AND SEMINAR ON CHEMISTRY EDUCATION RESEARCH AND PRACTICE (CERP) WILL: (1) STIMULATE MORE AND BETTER CHEMISTRY EDUCATION RESEARCH AND SCHOLARLY TEACHING IN CHEMISTRY WITH INCREASED COORDINATION AMONG RESEARCH PROGRAMS AND THE INTENTIONAL IMPLEMENTATION OF EVIDENCE-BASED TEACHING INNOVATIONS; (2) BUILD A MORE DIVERSIFIED GROUP OF SCHOLARS CARRYING OUT CHEMISTRY EDUCATION RESEARCH AND SCHOLARLY TEACHING IN CHEMISTRY; AND (3) BROADEN EARLY SCHOLARS? EXPERTISE IN FRAMING RESEARCH QUESTIONS, EMPLOYING DIVERSE RESEARCH METHODS, AND APPLYING THEORETICAL ORIENTATIONS BY DELIBERATELY ORGANIZING SESSIONS ON THE ALIGNMENT AMONG THESE CORE RESEARCH SKILLS. THESE THREE GOALS WILL BE ATTAINED THROUGH A CAREFULLY DESIGNED PROGRAM AND DIVERSE AND HIGHLY QUALIFIED SPEAKER AND DISCUSSION LEADER SELECTION COMPLEMENTED BY THE INTIMATE CONFERENCE ENVIRONMENT AFFORDED BY A GRC AND A GRS. SPECIFICALLY, THE GRS PROVIDES A SPECIAL OPPORTUNITY FOR GRADUATE STUDENTS AND POSTDOCTORAL FELLOWS TO FORM PROFESSIONAL NETWORKS, RECEIVE FEEDBACK ON THEIR WORK, AND ENGAGE WITH LEADERS IN THE FIELD FROM OUTSIDE OF THEIR OWN RESEARCH GROUPS. THE GRC PROGRAM INCLUDES TRANSFORMATIVE CONCEPTS, PARTICULARLY IN THE AREAS OF DIVERSITY, EQUITY, INCLUSION, AND BELONGING AS WELL AS SCHOLARLY RESPONSES TO THE COVID-19 PANDEMIC?S EFFECT ON CHEMISTRY EDUCATION RESEARCH AND PRACTICE. THE STRUCTURE AND CONTENT OF THE GORDON RESEARCH SEMINAR AND CONFERENCE ON CHEMISTRY EDUCATION RESEARCH AND PRACTICE ARE CAREFULLY CONCEIVED AND ORGANIZED TO ACHIEVE ITS THREE GOALS. MORE BROADLY, THE DIVERSE GROUP OF SPEAKERS AND DISCUSSION LEADERS, THE INAUGURAL CERP GRS, AND THE GRC POWER HOUR WILL CONTRIBUTE TO ALL CONFEREES? DEVELOPMENT AND BUILD AWARENESS TO SUPPORT THOSE WHO HAVE BEEN HISTORICALLY EXCLUDED IN SCIENCE. ADDITIONALLY, THE CONCURRENT PROGRAMMING AND NETWORKING SEGMENTS WILL FURTHER CONVERSATIONS ABOUT UNCONSCIOUS BIAS, MENTORING AND SPONSORSHIP, AND STRATEGIES FOR ADDRESSING HARASSMENT AND INAPPROPRIATE BEHAVIOR. SUCH DISCUSSIONS AND INTERACTIONS WILL HELP SEED THE CULTURE CHANGE NEEDED TO SUPPORT THE PROFESSIONAL GROWTH OF ALL CHEMISTS. THE NSF IUSE: EDU PROGRAM SUPPORTS RESEARCH AND DEVELOPMENT PROJECTS TO IMPROVE THE EFFECTIVENESS OF STEM EDUCATION FOR ALL STUDENTS. THROUGH THE ENGAGED STUDENT LEARNING TRACK, THE PROGRAM SUPPORTS THE CREATION, EXPLORATION, AND IMPLEMENTATION OF PROMISING PRACTICES AND TOOLS. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

2017 & 2019 GLYCOBIOLOGY GORDON RESEARCH CONFERENCE & GORDON RESEARCH SEMINAR

CONFERENCE: 2023 CHEMICAL OCEANOGRAPHY GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR -THE CHEMICAL OCEANOGRAPHY GORDON RESEARCH CONFERENCE BRINGS TOGETHER MEMBERS OF THE SCIENTIFIC COMMUNITY, GRADUATE STUDENTS, POSTDOCS, AND EARLY CAREER SCIENTISTS TO DISCUSS NEW, CUTTING-EDGE RESEARCH IN CHEMICAL OCEANOGRAPHY AND MARINE CHEMISTRY. THE NATIONAL SCIENCE FOUNDATION, ALONG WITH THE GORDON RESEARCH CONFERENCE, WILL CO-SPONSOR THE PARTICIPATION OF 15 DISCUSSION LEADERS AND SPEAKERS AS WELL AS 20 GRADUATE STUDENTS, POSTDOCS, OR EARLY CAREER INVESTIGATORS ATTENDING THIS CONFERENCE. IN ADDITION, THIS AWARD WILL SUPPORT EARLY CAREER PARTICIPANTS (POSTDOCS AND STUDENTS) ATTENDING THE GORDON RESEARCH SEMINAR (GRS), A 2-DAY WORKSHOP HELD PRIOR TO THE GRC MEETING THAT AIMS TO BUILD A COHORT OF EARLY CAREER CHEMICAL OCEANOGRAPHERS. THE 2023 GORDON RESEARCH CONFERENCE ON CHEMICAL OCEANOGRAPHY WILL BE HELD AT SOUTHERN NEW HAMPSHIRE UNIVERSITY ON JULY 16-21, 2023. THE PRIMARY GOAL OF THE CONFERENCE IS TO PROVIDE A FORUM THAT BRINGS TOGETHER SCIENTISTS WHO ARE LEADING CONTRIBUTORS IN THE FIELD OF MARINE CHEMISTRY ALONG WITH GRADUATE STUDENTS AND POSTDOCS TO EXCHANGE IDEAS ON NEW, INNOVATIVE RESEARCH. PRESENTATIONS AND DISCUSSIONS AT THE 2023 GORDON RESEARCH CONFERENCE WILL REVOLVE AROUND THE THEME OF TRACERS IN THE SEA? WITH A FOCUS ON THE MOLECULES, ELEMENTS, AND ISOTOPES THAT ARE USED AS TRACERS OF BIOGEOCHEMICAL AND PHYSICAL PROCESSES IN THE PAST AND THE PRESENT OCEAN. SESSION TOPICS AT THE 2023 GORDON RESEARCH CONFERENCE INCLUDE: (1) TRACERS OF BIOGEOCHEMICAL PROCESSES IN THE SEA; (2) GEOCHEMICAL PROXIES; (3) VERTICAL EXPORT; (4) LIFE AT THE MARGINS AND ITS INFLUENCE ON OCEAN CHEMISTRY; (5) EMERGING ANTHROPOGENIC IMPACTS ON OCEAN CHEMISTRY; (6) ANTHROPOGENIC TRACERS IN THE SEA; (7) GASES IN THE OCEAN?S INTERIOR; AND (8) CONTROLS ON DISSOLVED ORGANIC MATTER ACCUMULATION. THERE WILL ALSO BE A SESSION ON LATE-BREAKING TOPICS. THE CHEMICAL OCEANOGRAPHY GORDON RESEARCH CONFERENCE HAS BECOME RECOGNIZED AS AN IMPORTANT VENUE TO EXCHANGE IDEAS IN THE INTERDISCIPLINARY FIELD OF MARINE CHEMISTRY AND TO FORGE NEW SCIENTIFIC COLLABORATIONS. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

TAS::57 3600::TAS "2020 MULTIFUNCTIONAL MATERIALS AND STRUCTURES GORDON RESEARCH CONFERENCES,"

2015 INTERIOR OF THE EARTH GRC/GRS

2010 PROPROTEIN PROCESSING TRAFFICKING AND SECRETION; GORDON RESEARCH CONFERENC

2009 INSULIN-LIKE GROWTH FACTORS IN PHYSIOLOGY AND DISEASE GORDON RESEARCH CONFER

CANNABINOID

2023 LUNG DEVELOPMENT, INJURY AND REPAIR GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR - PROJECT SUMMARY: THE 2023 LUNG DEVELOPMENT, INJURY AND REPAIR GORDON RESEARCH CONFERENCE (GRC) AND ASSOCIATED GORDON RESEARCH SEMINAR (GRS) WILL BE HELD AUGUST 12-18, 2023 IN WATERVILLE VALLEY, NH. THE THEME FOR THE 2023 LUNG GRC IS "POST-COVID RETURN TO RESPIRATORY HEALTH". THE 2023 LUNG GRC COMES AT A CRITICAL TIME, BECAUSE POST-ACUTE COVID-19 SYNDROME INCLUDING CHRONIC CONSEQUENCE OF SEVERE LUNG INJURIES WILL BE COMING INTO FOCUS, HEIGHTENING OUR NEED TO UNDERSTAND AND COMBAT THE DYSFUNCTIONAL REPAIR AND REMODELING THAT FOLLOWS SEVERE INJURY. ACCORDING TO STATISTICS FROM THE WORLD HEALTH ORGANIZATION, THE GLOBAL BURDEN OF LUNG DISEASE CONTINUES TO RISE, WITH >4 MILLION DEATHS ANNUALLY WORLDWIDE ATTRIBUTED TO CHRONIC RESPIRATORY DISEASES, INCLUDING COPD, ASTHMA, AND PULMONARY FIBROSIS. WHILE BASIC SCIENTIFIC RESEARCH IS MAKING SUBSTANTIAL STRIDES FORWARD IN UNDERSTANDING MOLECULAR, CELLULAR AND TISSUE LEVEL MECHANISMS DRIVING RESPIRATORY DISEASES, TRANSLATION OF THESE FINDINGS TOWARD EARLY DETECTION AND EFFECTIVE REPAIR AND RESTORATION OF LUNG FUNCTION IN CHRONIC RESPIRATORY DISEASES REMAINS A MAJOR BARRIER. MEETING THIS CHALLENGE REQUIRES THE INTEGRATION OF KNOWLEDGE FROM EXPERTS SPANNING LUNG DEVELOPMENT, MOLECULAR AND CELL BIOLOGY, GENOMICS AND EPIGENOMICS, PHYSIOLOGY, BIOENGINEERING, MATRIX BIOLOGY AS WELL AS PHYSICIANS AND TRANSLATIONAL EXPERTS IMMERSED IN THE DIAGNOSIS AND TREATMENT OF HUMAN DISEASE. LUNG GRC/GRS 2023 WILL BRING DIVERSE EXPERTS TOGETHER TO DISSEMINATE AND DEBATE THE LATEST FINDINGS IN THE FIELDS OF LUNG DEVELOPMENT, INJURY AND REPAIR, AND TO FORMULATE NEW IDEAS, COLLABORATIONS AND APPROACHES THAT WILL TRANSLATE BIOLOGIC DISCOVERIES TOWARD MEANINGFUL ADVANCES IN RESPIRATORY MEDICINE. A MAJOR EMPHASIS OF THE LUNG GRC AND GRS IS TO STRENGTHEN THE PIPELINE OF SCIENTISTS AND CLINICIANS FOCUSED ON LUNG DEVELOPMENT, INJURY AND REPAIR. FUNDS FROM THIS R13 WILL BE SPECIFICALLY TARGETED TO PROMOTE PARTICIPATION IN THE CONFERENCE BY WOMEN, UNDER-REPRESENTED MINORITIES AND PEOPLE WITH DISABILITIES, GRADUATE STUDENTS, POSTDOCTORAL FELLOWS, AND EARLY CAREER INVESTIGATORS. THE UNIQUE ATTRIBUTES OF THE GRC (OPEN SCIENTIFIC EXCHANGE, SECLUDED LOCATION TO MAXIMIZE ENGAGEMENT, TRADITION TO SHARE UNPUBLISHED DATA, ABUNDANT TIME FOR DISCUSSION) AND GRS (CLOSE TRAINEE INTERACTIONS WITH PEERS AND MENTORS) PROVIDE AN OPPORTUNITY FOR FORMAL AND INFORMAL INTERACTIONS AND COLLABORATIONS THAT ARE LIKELY TO HAVE SIGNIFICANT AND SUSTAINED IMPACT ON THE FIELD. THE 2023 LUNG DEVELOPMENT, INJURY AND REPAIR GRC/GRS WILL THUS PROMOTE ACCELERATED PROGRESS IN UNDERSTANDING AND TREATING CHRONIC LUNG DISEASES, AND HELP TO ENSURE THE VITALITY AND GROWTH OF A DIVERSE PIPELINE OF CLINICIANS AND SCIENTISTS CAPABLE OF ADDRESSING THE GROWING BURDEN OF LUNG DISEASES.

2018 AUDITORY SYSTEM GORDON RESEARCH CONFERENCE & GORDON RESEARCH SEMINAR

2016 THE AUDITORY SYSTEM GORDON RESEARCH CONFERENCE & GORDON RESEARCH SEMINAR

2011 CATECHOLAMINES GORDON RESEARCH CONFERENCE

2009 CATECHOLAMINES GORDON RESEARCH CONFERENCE

CONFERENCE: 2024 ENVIRONMENTAL SCIENCES: WATER GORDON RESEARCH CONFERENCE -THIS GRANT WILL SUPPORT THE ENVIRONMENTAL SCIENCES: WATER GORDON RESEARCH CONFERENCE AT HOLDERNESS, NEW HAMPSHIRE. THE THEME OF THE 2024 CONFERENCE IS ADDRESSING CURRENT CHALLENGES IN AQUATIC SCIENCES THROUGH INNOVATIVE SOLUTIONS. THE WEEK-LONG CONFERENCE WILL FOCUS ON THREE MAJOR THEMES: 1) CHEMICAL AND BIOLOGICAL EXPOSURES; 2) ENVIRONMENTAL AND HUMAN HEALTH IMPACTS; AND 3) INNOVATIVE SOLUTIONS FOR THE MANAGEMENT OF WATER RESOURCES. THE FOCUS ON IMPROVING WATER QUALITY WILL BENEFIT BOTH HUMAN AND ECOLOGICAL HEALTH. THE IMMERSIVE FORMAT OF THE CONFERENCE WILL FACILITATE NETWORKING AND COLLABORATIVE EXCHANGE AMONG PARTICIPANTS. THE DEVELOPMENT OF THE NEXT GENERATION OF ENVIRONMENTAL SCIENCE LEADERS WILL BE FOSTERED THROUGH INTERACTIONS WITH LEADING RESEARCHERS IN ACADEMIA, INDUSTRY, AND GOVERNMENT. DIVERSITY AND INCLUSION IN THE DISCIPLINE WILL BE ENHANCED THROUGH SCHOLARSHIPS FOR ATTENDEES FROM UNDERSERVED GROUPS. EDUCATIONAL AND CAREER DEVELOPMENT SUCCESS WILL BE ASSESSED BY SURVEYS OF ALL PARTICIPANTS AT THE END OF THE CONFERENCE. THE GOAL OF THIS PROJECT IS TO SUPPORT THE ENVIRONMENTAL SCIENCES: WATER GORDON RESEARCH CONFERENCE, TO BE HELD JUNE 2024 IN HOLDERNESS, NEW HAMPSHIRE. THE CONFERENCE WILL FEATURE A PROGRAM OF THOUGHT-PROVOKING RESEARCH THAT STRIVES TO ADDRESS TODAY'S MOST PRESSING ENVIRONMENTAL CHALLENGES. SOLUTIONS TO THESE CHALLENGES RELY ON RESEARCH AT THE INTERSECTIONS OF TRADITIONAL DISCIPLINES, WHICH WILL BE FOSTERED BY BRINGING TOGETHER 190 PARTICIPANTS TO DISCUSS INNOVATIONS IN WATER QUALITY SCIENCE. THE IMMERSIVE FORMAT WILL ENABLE MEANINGFUL NETWORKING AND EXCHANGES OF IDEAS AMONG CONFERENCE PARTICIPANTS. STUDENT AND POST-DOCTORAL RESEARCH TRAINEES WILL BE FULLY ENGAGED IN THIS IMMERSIVE SCIENTIFIC CONFERENCE. THEIR DEVELOPMENT AS RESEARCHERS WILL BE FOSTERED THROUGH INTERACTIONS WITH LEADING RESEARCHERS IN ACADEMIA, INDUSTRY, AND GOVERNMENT. ALL INVITED PRESENTERS WILL BE FIRST TIME SPEAKERS AT THE MEETING, WHICH WILL ADVANCE THE NEXT GENERATION OF ENVIRONMENTAL SCIENCE LEADERS. THE MEETING WILL FOSTER DIVERSITY AND INCLUSION IN THE DISCIPLINE THROUGH SCHOLARSHIPS FOR ATTENDEES FROM UNDERSERVED GROUPS. THE SUCCESS AND IMPACTS OF THE CONFERENCE WILL BE ENHANCED THROUGH NEW APPROACHES TO FOSTERING NETWORKING AND SOCIAL INTERACTIONS ACROSS CAREER STAGES THROUGH THE ESTABLISHMENT OF MENTORING GROUPS AND STRUCTURED SOCIAL INTERACTIONS. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

2017 ENVIRONMENTAL NANOTECHNOLOGY GRC/GRS

2020 INDUSTRIAL ECOLOGY GRC; NEWRY MAINE, JUNE 13-19, 2020

SYSTEMS CHEMISTRY FROM CONCEPTS TO CONCEPTIONS GORDON RESEARCH CONFERENCE

2017 INTERIOR OF THE EARTH GRC/GRS

2024 OCEAN MIXING GORDON RESEARCH CONFERENCE AND SEMINAR

CONFERENCE: 2024 GORDON RESEARCH CONFERENCE ON OCEAN MIXING: UNDERSTANDING THE ROLE OF OCEAN MIXING ACROSS SCALES ON CLIMATE, ECOSYSTEMS, AND OCEAN SOLUTIONS TO SOCIETAL PROBLEMS -THIS GRANT IS TO SUPPORT THE 2024 GORDON RESEARCH CONFERENCE (GRC) ON OCEAN MIXING, AS WELL AS THE GORDON RESEARCH SEMINAR (GRS) FOR EARLY CAREER SCIENTISTS. THESE WILL PROVIDE A FORUM TO IMPROVE THE BROADER COMMUNITY?S UNDERSTANDING OF TURBULENT MIXING IN THE OCEAN, INCLUDING THE INTERACTIONS ACROSS SCALES, AND PRACTICAL APPLICATIONS. OCEAN MIXING HAS IMPORTANT IMPACTS IN MANY AREAS OF SOCIETAL RELEVANCE, INCLUDING CLIMATE (E.G. OCEAN HEAT AND CARBON UPTAKE, THE MERIDIONAL OVERTURNING CIRCULATION), WEATHER (E.G. HURRICANE INTENSITY), POLLUTION (E.G. MARINE PLASTICS) AND ECOSYSTEMS (E.G. HYPOXIA). MORE RECENTLY, AS THE POSSIBLE ROLE OF THE OCEAN IN MITIGATING CLIMATE AND ECOSYSTEM CHANGES IS BEING EXPLORED, CHANGES TO MIXING RESULTING FROM OCEAN RENEWABLE ENERGY AND INFLUENCE OF OCEAN MIXING ON ENHANCED OCEAN CARBON DIOXIDE REMOVAL MUST ALSO BE CONSIDERED. THE 2024 GRC WILL MAKE THE CONNECTION BETWEEN FUNDAMENTAL STUDIES OF OCEAN MIXING AND THESE IMPORTANT IMPACTS AND APPLICATIONS. THE GRC FORMAT IS DESIGNED TO GENERATE VIGOROUS DISCUSSION AND FOSTER NEW COLLABORATIONS, STIMULATING NEW UNDERSTANDING. THE GRC WILL STRENGTHEN THE CONNECTION BETWEEN FUNDAMENTAL STUDIES OF OCEAN MIXING AND APPLICATIONS TO SOCIETALLY RELEVANT PROBLEMS, WITH CONSEQUENT BENEFITS TO SOCIETY. THE GRC WILL ALSO FOSTER AN INCLUSIVE OCEAN MIXING COMMUNITY BY PROMOTING NEW INTERACTIONS BETWEEN PEOPLE WORKING ON DIFFERENT ASPECTS, USING DIFFERENT APPROACHES, AND AT VARIED CAREER LEVELS, THROUGH FOCUSED DISCUSSIONS AND FACILITATED INFORMAL NETWORKING ACTIVITIES. THE GRS WILL ENABLE THE FULL PARTICIPATION OF EARLY CAREER SCIENTISTS IN THIS COMMUNITY, CONTRIBUTING TO WORKFORCE DEVELOPMENT. NSF SUPPORT WILL HELP TO ELIMINATE FINANCIAL BARRIERS TO PARTICIPATION, BY SUPPORTING ATTENDANCE OF EARLY CAREER SCIENTISTS AND SCIENTISTS FROM HISTORICALLY UNDER-REPRESENTED GROUPS. OCEAN MIXING, WHICH CAN LOOSELY BE DEFINED AS TIME-VARIABLE MOTION WHICH INCREASES FLUXES OF TRACERS ABOVE LEVELS SET BY MOLECULAR DIFFUSION, ENCOMPASSES A WIDE VARIETY OF PROCESSES TAKING PLACE OVER A LARGE RANGE OF SCALES, FROM MESOSCALE GEOSTROPHIC EDDIES TO ISOTROPIC TURBULENCE. BETWEEN THESE SCALES MANY DIFFERENT INSTABILITY PROCESSES EXCITE MOTIONS WHICH LEAD TO MIXING. ALL THESE PROCESSES, EXCEPT FOR THE LARGEST MESOSCALE EDDIES, OCCUR ON SCALES TOO SMALL TO EXPLICITLY SIMULATE IN THE OCEAN COMPONENT OF CLIMATE MODELS, REQUIRING PARAMETERIZATIONS OF THEIR IMPACT ON TRACER FLUXES TO ACCURATELY CAPTURE THEIR EFFECT ON THE LARGE SCALE OCEAN. THE DEVELOPMENT OF PARAMETERIZATIONS REQUIRES EXPERTS IN DIFFERENT ASPECTS OF OCEAN MIXING - OBSERVATIONS, THEORY, PROCESS SIMULATION, LABORATORY EXPERIMENTS, REGIONAL AND CLIMATE MODELING - TO WORK TOGETHER. THE GRC STIMULATES THIS COLLABORATION BETWEEN SCIENTISTS USING DIFFERENT APPROACHES AND FOCUSED ON DIFFERENT SCALES, TO BETTER UNDERSTAND OCEAN MIXING. THE GRS PROVIDES A FORUM FOR EARLY CAREER SCIENTISTS TO NETWORK WITH THEIR PEERS AND ENGAGE IN PROFESSIONAL DEVELOPMENT PRIOR TO THE MAIN CONFERENCE. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

2015 UNDERGRADUATE BIOLOGY EDUCATION RESEARCH GORDON RESEARCH CONFERENCE

2009 MOLECULAR PHARMACOLOGY GORDON RESEARCH CONFERENCE

2025 EPITHELIAL DIFFERENTIATION AND KERATINIZATION GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR - PROJECT SUMMARY THE 2025 GORDON RESEARCH CONFERENCE ON EPITHELIAL DIFFERENTIATION AND KERATINIZATION (GRC-EDK) IS THE LEADING INTERNATIONAL MEETING IN THE FIELD OF EPITHELIAL BIOLOGY. SINCE ITS INCEPTION IN 1979, THE BIENNIAL GRC-EDK HAS CONTRIBUTED TO SCIENTIFIC ADVANCES AND SHAPED THERAPEUTIC APPROACHES FOR TREATING SKIN CONDITIONS. FOR OVER FOUR DECADES, THE GRC-EDK HAS HAD A HIGH LEVEL OF ATTENDANCE, THE CONSISTENT PARTICIPATION OF WORLD-RENOWNED EXPERTS IN THE FIELD, AND HIGHLY FAVORABLE REVIEWS FROM CONFERENCE ATTENDEES. THE 2025 GRC-EDK CONFERENCE IS ENTITLED EPITHELIAL DEVELOPMENT, AGING, DISEASE, AND REGENERATION ACROSS CELLS AND SYSTEMS AND WILL TAKE PLACE IN VENTURA BEACH, CALIFORNIA, FROM JUNE 1-6, 2025. THE 2025 GRC-EDK WILL CELEBRATE ITS 46TH YEAR, CONTINUING ITS TRADITION OF ADDRESSING CUTTING-EDGE BASIC QUESTIONS IN EPITHELIAL BIOLOGY AND WAYS OF TRANSLATING THESE DISCOVERIES INTO DISEASE TREATMENT. IT WILL SHOWCASE RECENT CONCEPTUAL AND TECHNOLOGICAL ADVANCES COMPRISING STEM CELL BIOLOGY, REGENERATIVE MEDICINE, CANCER, IMMUNITY, AGING, EPIGENETICS, SKIN DISEASES, NOVEL SINGLE-CELL AND SPATIAL TRANSCRIPTOMICS TECHNOLOGIES, AND GLOBAL GENOMICS. GRC-EDK ALSO ACTS AS A PLATFORM TO SUPPORT THE CAREERS OF A FULL RANGE OF INVESTIGATORS, INCLUDING WOMEN AND MEN, YOUNG INVESTIGATORS, AND INVESTIGATORS FROM DIFFERENT CULTURAL AND ETHNIC BACKGROUNDS. MORE THAN 15% OF THE INVITED SPEAKERS ARE FROM FIELDS BEYOND THE IMMEDIATE SCOPE OF THE CONFERENCE, 85% DID NOT PRESENT AT THE PREVIOUS MEETING, AND OVER 30% OF SPEAKERS WILL BE SELECTED FROM ABSTRACT SUBMISSIONS TO ENSURE PLENTIFUL OPPORTUNITIES FOR JUNIOR FACULTY AND TRAINEES. THE RELATIVELY SECLUDED LOCATION FOR THE 2025 GRC-EDK AND THE ALLOCATED INFORMAL AFTERNOON PERIODS ARE CHOSEN TO MAXIMIZE THE POTENTIAL FOR IN-DEPTH SCIENTIFIC DISCUSSIONS, MENTORING, AND THE INITIATION OF COLLABORATIONS AMONG CONFERENCE PARTICIPANTS. THE POWER HOUR IS AN IMPORTANT PART OF THE GRC-EDK MEETING AND WILL ENCOURAGE DISCUSSIONS ON OVERCOMING DISCRIMINATION AND FACILITATING DIVERSITY AND INCLUSION IN THE SCIENTIFIC COMMUNITY. THE COMMITMENT TO NURTURING THE NEXT GENERATION OF SCIENTISTS WILL CONTINUE WITH THE 6TH GORDON RESEARCH SEMINAR ON EPITHELIAL DIFFERENTIATION AND KERATINIZATION (GRS-EDK), SCHEDULED AT THE SAME LOCATION AND JUST BEFORE THE MAIN CONFERENCE FROM MAY 31-JUNE 1, 2025. THIS SEMINAR IS ORGANIZED BY AND FOR TRAINEES AND OFFERS A SUPPORTIVE ENVIRONMENT FOR PRESENTING RESEARCH, NETWORKING, AND FOSTERING COLLABORATIONS. A CAREER MENTORING PANEL AT THE GRS-EDK WILL ADDRESS KEY TOPICS SUCH AS CAREER DEVELOPMENT, CHOICES BETWEEN ACADEMIA AND INDUSTRY, AND THE CRITICAL IMPORTANCE OF DIVERSITY IN SCIENCE. TAKEN TOGETHER, THE 2025 GRC/GRS-EDK EXEMPLIFIES THE NIAMS INSTITUTE'S STRATEGY WITH THE FOLLOWING MAIN OBJECTIVES: (I) TO ADVANCE PIONEERING RESEARCH IN SKIN BIOLOGY, (II) TO FACILITATE THE TRANSITION OF SCIENTIFIC DISCOVERIES TO CLINICAL PRACTICE, AND (III) TO SUPPORT THE PROFESSIONAL DEVELOPMENT OF EARLY-CAREER SCIENTISTS AND TRAINEES TO SUSTAIN INNOVATION IN THE FIELD.

FUNDS ARE REQUESTED TO PARTIALLY SUPPORT THE 2020 GORDON CONFERENCE ON THE ORIGINS OF LIFE (GRC) AND THE 2020 GORDON RESEARCH SEMINAR (GRS) ON THE ORIGINS OF LIFE

2014 COLLOIDAL SEMICONDUCTOR NANOCRYSTALS GORDON RESEARCH CONFERENCE, JULY 20-25, 2014

2013 INTERIOR OF THE EARTH GRC/GRS

2020 MULTISCALE PLANT VASCULAR BIOLOGY GRC/GRS, NEWRY, MAINE, JUNE 7-12,2020

2012 PHYSICS RESEARCH & EDUCATION GRC

2024 EPITHELIAL STEM CELLS AND NICHES GORDON RESEARCH CONFERENCE AND SEMINAR - ABSTRACT ADULT EPITHELIA REGENERATE DURING ADULT LIFE DUE TO THE CONSTANT ACTIVITY OF STEM CELL POOLS. STEM CELLS MAINTAIN TISSUE HOMEOSTASIS AND REPAIR INJURY BY CLOSE COMMUNICATION WITH THEIR TISSUE ENVIRONMENT, KNOWN AS "NICHE.” NICHES ARE COMPLEX, STRUCTURED ARRAYS OF DIFFERENT CELL TYPES THAT GUIDE TISSUE STEM CELL DYNAMICS. THE ULTIMATE GOAL OF UNDERSTANDING EPITHELIAL STEM CELL REGULATION IS TO REPAIR OR REPLACE CELLS OR ORGANS DAMAGED BY INJURY, DISEASE, AND AGING. THE STRATEGIES VARY FROM GENERATING CELL TYPES AND TISSUES IN A DISH FOR TRANSPLANTATION PURPOSES TO DIRECTLY STIMULATING THE DAMAGED ORGAN IN THE LIVING ORGANISM. THIS FIELD HAS BEEN EXPONENTIALLY GROWING FOR THE PAST DECADE. TISSUES SUCH AS HUMAN SKIN AND CORNEA HAVE ALREADY BEEN GROWN IN 3D CULTURES AND USED IN CLINICS TO FIGHT OTHERWISE INCURABLE MEDICAL CONDITIONS. THE GRC ON EPITHELIAL STEM CELLS AND NICHES WILL FOCUS ON COMPARATIVE PRINCIPLES OF ADULT EPITHELIAL STEM CELL DYNAMICS AND NICHE SIGNALING IN THE HOMEOSTASIS OF DIFFERENT TISSUES. THIS CONFERENCE WILL INCLUDE WORK ON THE MOLECULAR CONTROL OF STEM CELL FUNCTION FROM THE EPIDERMIS AND ITS APPENDAGES, INTESTINE, LUNG, MAMMARY GLAND, CORNEA, PROSTATE, AND EMERGING WORK FROM OTHER EPITHELIAL TISSUES. ALL MODEL ORGANISMS ARE WELCOME. THIS GRC HAS HELD MEETINGS IN 2016, 2018, AND 2022. WE WILL CONTINUE TO BRING IN BOTH NEW AND VETERAN SPEAKERS TO ALLOW A VARIETY OF PARTICIPANTS TO CONTRIBUTE TO THIS EXCITING MEETING OVER THE COMING YEARS. IN PARTICULAR, FOR THE 2024 MEETING, WE HAVE BUILT A SCIENTIFIC PROGRAM THAT EMPHASIZES KEY CUTTING-EDGE AREAS IN EPITHELIAL BIOLOGY, INCLUDING ORGANOID TECHNIQUES, IMAGING AND SINGLE- CELL ANALYSIS, BIOENGINEERING, METABOLISM, MODELING DISEASE, AND MECHANOBIOLOGY. IN ADDITION, WE WILL SUPPORT THE ATTENDANCE OF GRADUATE STUDENTS, POSTDOCS, AND EARLY CAREER SCIENTISTS AS THEY MAKE THEIR WAY INTO THIS EXCITING FIELD OF STUDY BY HOSTING A GRS IN THE TWO DAYS PRIOR TO THIS GRC. A CRITICAL FEATURE OF THE GRC’S SCIENTIFIC MISSION IS TO ENGAGE THE NEXT GENERATION OF SCIENTISTS. WE ARE CONTINUING OUR TWO-DAY GORDON RESEARCH SEMINAR (GRS) FOR GRADUATE STUDENTS AND POSTDOCTORAL FELLOWS THAT WILL PRECEDE THIS GRC. THE GRS WILL ALLOW STUDENTS AND FELLOWS TO SHARE AND DISCUSS UNPUBLISHED DATA AND TECHNICAL BREAKTHROUGHS, FAVORING COLLABORATIVE EFFORTS AND SPARKING PROVOCATIVE HYPOTHESES TO BE DISCUSSED ON THE FLOOR OF THE MAIN CONFERENCE. FURTHERMORE, THE PARTICIPANTS WILL HAVE THE OPPORTUNITY TO ESTABLISH TIGHT PROFESSIONAL RELATIONSHIPS FROM WHICH THEY WILL BENEFIT THROUGHOUT THEIR CAREERS. GRS PARTICIPANTS WILL BE EXPECTED TO STAY FOR THE GRC, FURTHER CONTRIBUTING TO THE EDUCATIONAL VALUE OF THIS CONFERENCE.

THE LACTIC ACID BACTERIA BIOLOGY, SYMBIOSES AND APPLICATIONS GRC IS A PREMIER, INTERNATIONAL SCIENTIFIC CONFERENCE FOCUSED ON ADVANCING THE FRONTIERS OF SCIENCE THROUGH THE PRESENTATION OF CUTTING-EDGE AND UNPUBLISHED RESEARCH, PRIORITIZING TIME FOR DISCUSSION AFTER EACH TALK AND FOSTERING INFORMAL INTERACTIONS AMONG SCIENTISTS OF ALL CAREER STAGES. THE CONFERENCE PROGRAM INCLUDES A DIVERSE RANGE OF SPEAKERS AND DISCUSSION LEADERS FROM INSTITUTIONS AND ORGANIZATIONS WORLDWIDE, CONCENTRATING ON THE LATEST DEVELOPMENTS IN THE FIELD. THE CONFERENCE IS FIVE DAYS LONG AND HELD IN A REMOTE LOCATION TO INCREASE THE SENSE OF CAMARADERIE AND CREATE SCIENTIFIC COMMUNITIES, WITH LASTING COLLABORATIONS AND FRIENDSHIPS. IN ADDITION TO PREMIER TALKS, THE CONFERENCE HAS DESIGNATED TIME FOR POSTER SESSIONS FROM INDIVIDUALS OF ALL CAREER STAGES, AND AFTERNOON FREE TIME AND COMMUNAL MEALS ALLOW FOR INFORMAL NETWORKING OPPORTUNITIES WITH LEADERS IN THE FIELD.THIS GRC WILL BE THE FIRST OF ITS KIND TO EXPLORE MULTIDISCIPLINARY RESEARCH IN LACTIC ACID BACTERIA (LAB). WHILE CLASSICALLY ASSOCIATED WITH FOOD FERMENTATIONS SUCH AS YOGURTS AND SOURDOUGH BREADS, LAB ARE NOW RECOGNIZED AS BEING CRITICAL MEMBERS OF DIFFERENT ECOSYSTEMS INCLUDING THE BENEFICIAL MICROBIOMES OF HUMANS, ANIMALS, AND INSECTS, WITH MAJOR IMPORTANCE IN FOOD, MEDICINE, AND INDUSTRY. LAB WERE AMONG THE FIRST MICROORGANISMS ISOLATED AND CHARACTERIZED BY PASTEUR, LISTER, AND OTHER PIONEERING MICROBIOLOGISTS. LAB WERE ALSO KEY MODEL ORGANISMS USED IN THE DEVELOPMENT OF MOLECULAR BIOLOGY AND INDUSTRIAL MICROBIOLOGY, PROVIDING FUNDAMENTAL ADVANCEMENTS IN GENETICS, METABOLISM AND THE DISCOVERY OF CRISPR-CAS SYSTEMS. THESE ACHIEVEMENTS RESULTED FROM INTERDISCIPLINARY SCIENCE INVOLVING EXPERTISE IN BOTH APPLIED AND FUNDAMENTAL RESEARCH. THE PURPOSE OF THIS MEETING IS TO BRING TOGETHER EXPERTS IN MULTIPLE DISCIPLINES TO IDENTIFY, DEVELOP, AND COORDINATE NEW RESEARCH DIRECTIONS USING LAB.THIS CONFERENCE WILL BE HELD IN VENTURA, CALIFORNIA, USA, FROM JULY 23 TO 28, 2023. SESSION TOPICS COVER KEY AREAS INCLUDING LAB DIVERSITY AND EVOLUTION, EXTRACELLULAR COMPOSITION AND CELL SURFACE BIOLOGY, DNA ACQUISITION AND PHAGE DEFENSE, ECOLOGY AND SYSTEMS BIOLOGY. A MAJOR FOCUS IS THE DIVERSE APPLICATIONS OF LAB TO ADDRESS THE MAJOR HEALTH, FOOD SECURITY, AND ENVIRONMENTAL CHALLENGES OF THE TWENTY-FIRST CENTURY. THE MEETING WILL PROVIDE THE LATEST UNPUBLISHED EXCITING RESEARCH DISCOVERIES FROM BOTH SENIOR INVESTIGATORS IN THE FIELD AS WELL AS EARLY-STAGE INVESTIGATORS. THERE WILL BE A STRONG EMPHASIS ON LIVELY DISCUSSION FOLLOWING EACH TALK, WITH AN EMPHASIS ON QUESTIONS FROM STUDENTS AND POSTDOCTORAL FELLOWS. BOTH THE POSTER SESSIONS AND AMPLE FREE TIME WILL PROVIDE AN ATMOSPHERE THAT FAVORS INFORMAL SCIENTIFIC EXCHANGES, FOSTERING THE DEVELOPMENT OF NEW IDEAS AND COLLABORATIONS.AN IMPORTANT GOAL OF THE GRC IS TO CULTIVATE THE NEXT GENERATION OF SCIENTIFIC LEADERS INCLUDING JUNIOR INVESTIGATORS, POSTDOCTORAL FELLOWS AND G,RADUATE STUDENTS BY PROVIDING A HIGHLY INTERACTIVE AND SUPPORTIVE ENVIRONMENT TO EXCHANGE IDEAS WITH CURRENT LEADERS IN THE FIELD. ALL ATTENDEES WILL HAVE THE OPPORTUNITY TO PRESENT POSTERS AND THE BEST ABSTRACTS WILL BE SELECTED FOR SHORT ORAL PRESENTATIONS IN THE REGULAR PROGRAM. THE PROGRAM WILL ALSO INCLUDE A POWER HOUR OPEN TO ALL PARTICIPANTS, WHICH IS DESIGNED TO INCREASE AWARENESS BY DISCUSSING ISSUES THAT WOMEN AND MINORITIES FACE IN THEIR SCIENTIFIC CAREERS. WE ENCOURAGE A COLLEGIAL AND SUPPORTIVE ATMOSPHERE AT THIS CONFERENCE, WITH ORGANIZED DISCUSSION SESSIONS AND OPPORTUNITIES FOR INFORMAL GATHERINGS IN THE AFTERNOONS AND EVENINGS. THIS BEAUTIFUL CALIFORNIA SUMMERTIME SETTING PROVIDES AN IDEAL ENVIRONMENT FOR SCIENTISTS FROM DIFFERENT DISCIPLINES TO EXCHANGE IDEAS, BRAINSTORM AND FOSTER CROSS-DISCIPLINARY COLLABORATIONS.

2024 LYSOSOMES AND ENDOCYTOSIS GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR - PROJECT SUMMARY NIH SUPPORTED RESEARCH AIMS TO ADVANCE OUR UNDERSTANDING OF BIOLOGICAL SYSTEMS, IMPROVE THE CONTROL OF DISEASE, AND ENHANCE HEALTH. DESPITE THE WELL-RECOGNIZED IMPORTANCE OF CONNECTING RESEARCHERS WORKING AT THE FOREFRONT OF FUNDAMENTAL CELL BIOLOGY WITH THOSE STUDYING THE PATHOGENESIS AND EVENTUAL TREATMENT OF DISEASE, CONFERENCES THAT BRIDGE THESE APPROACHES ARE REMARKABLY SCANT. THE 2024 GORDON RESEARCH CONFERENCE ON LYSOSOMES AND ENDOCYTOSIS WILL BE PARTICULARLY IMPACTFUL IN THIS AREA, WITH A THEME OF “MECHANISMS, MOLECULES AND THERAPEUTIC OPPORTUNITIES ACROSS THE ENDOLYSOSOMAL SYSTEM” AND A DISTINCTIVE FOCUS ON NEURODEGENERATIVE DISEASE INCLUDING ALZHEIMER’S DISEASE AND ALZHEIMER’S DISEASE RELATED DEMENTIAS (AD/ADRD). THIS CONFERENCE WILL FACILITATE INTERACTION AND COLLABORATION BETWEEN CELL BIOLOGISTS, NEUROSCIENTISTS, GENETICISTS, NEUROLOGISTS, AND OTHERS IN RELATED BIOMEDICAL FIELDS AND AT DIFFERENT STAGES OF THEIR CAREER. BY BRINGING TOGETHER THE LEADING EXPERTS WORKING TO UNDERSTAND NORMAL AND PATHOLOGIC FUNCTION ACROSS THE ENDOLYSOSOMAL SYSTEM, THE LYSOSOMES AND ENDOCYTOSIS GRC/GRS WILL BE A UNIQUE OPPORTUNITY TO DISSEMINATE KNOWLEDGE, FOSTER INTERDISCIPLINARY INTERACTIONS AND LEARNING, AND PROVIDE OUTSTANDING NETWORKING AND MENTORSHIP OPPORTUNITIES. THE GRC IS PRECEDED BY THE GORDON RESEARCH SEMINAR (GRS), A UNIQUE FORUM FOR TRAINEES AND EARLY CAREER SCIENTISTS TO PRESENT AND EXCHANGE NEW DATA AND CUTTING-EDGE IDEAS. THE GOALS OF THE LYSOSOMES AND ENDOCYTOSIS GRC/GRS ARE TO 1) PROVIDE A COMPREHENSIVE AND INTEGRATED PLATFORM FOR DISSEMINATING THE LATEST DISCOVERIES RELATED TO THE FUNCTION AND PHYSIOLOGY OF THE ENDOLYSOSOMAL SYSTEM; 2) BUILD BRIDGES BETWEEN BASIC AND DISEASE-FOCUSED RESEARCHERS; AND 3) FOSTER DISCUSSION OF NEW CONCEPTS, HYPOTHESES, TECHNICAL APPROACHES, AND RESEARCH COLLABORATIONS. AN IMPORTANT ASPECT OF THIS IS TO PROVIDE CAREER DEVELOPMENT OPPORTUNITIES FOR NEW FACULTY AND TRAINEES, ALONG WITH OPPORTUNITIES FOR WOMEN AND OTHERS FROM UNDERREPRESENTED GROUPS TO INTERACT WITH ESTABLISHED AND SUCCESSFUL SCIENTISTS. THESE GOALS WILL BE ACCOMPLISHED BY A BROAD-BASED AND INCLUSIVE SPEAKING PROGRAM, POSTER SESSIONS AT WHICH ALL ATTENDEES ARE ENCOURAGED TO PRESENT, AND INTENTIONAL EFFORTS TO ENCOURAGE DISCUSSION AND SOCIAL INTERACTION OUTSIDE OF PRESENTATIONS TO ALLOW FOR EXCHANGE OF IDEAS AND DEVELOPMENT OF COLLABORATIONS AND FUTURE TRAINING OPPORTUNITIES. THIS MEETING IS THE PREEMINENT INTERNATIONAL CONFERENCE FOR ADVANCING RESEARCH ON THE ENDOLYSOSOMAL SYSTEM AND WILL HIGHLIGHT THE LATEST IN NEW UNDERSTANDING OF ENDO-LYSOSOMAL FUNCTION WITH A PARTICULAR EMPHASIS ON HOW DEFECTS ACROSS THE ENDOLYSOSOMAL SYSTEM CONTRIBUTE TO THE TRIGGERING AND PROGRESSION OF NEURODEGENERATIVE DISEASES AND ESPECIALLY ALZHEIMER’S DISEASE AND RELATED DEMENTIAS (AD/ADRD).

2019 CARBON CAPTURE, UTILIZATION AND STORAGE GRC/GRS

2025 CELL BIOLOGY OF MEGAKARYOCYTES AND PLATELETS GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR - PROJECT SUMMARY THE GORDON RESEARCH CONFERENCE (GRC) AND GORDON RESEARCH SEMINAR (GRS) ON THE CELL BIOLOGY OF MEGAKARYOCYTES AND PLATELETS IS THE PREMIER INTERNATIONAL MEETING IN THE FIELD. EVERY OTHER YEAR, THIS CONFERENCE BRINGS TOGETHER ESTABLISHED AND JUNIOR INVESTIGATORS, GRADUATE AND POSTDOCTORAL TRAINEES, AS WELL AS INTERESTED INDUSTRY SCIENTISTS TO COMMUNICATE AND DISCUSS UNPUBLISHED DATA THAT ARE CRITICAL TO THE DEVELOPMENT AND DISORDERS OF THE MEGAKARYOCYTE LINEAGE. THE 2025 CONFERENCE, THE 10TH OF THIS GRC/GRS SERIES, WILL PROVIDE A COLLEGIAL AND OPEN SETTING TO FACILITATE NETWORKING, PROMOTE DISCUSSION AND FOSTER COLLABORATIONS AMONG CURRENT AND EMERGING LEADERS OF THE FIELD. THE LONG-TERM SCIENTIFIC MISSION OF THE CONFERENCE IS TO BRIDGE THE GAP BETWEEN RESEARCHERS WORKING ON VARIOUS ASPECTS OF THE LINEAGE, INCLUDING HEMATOPOIETIC STEM CELLS, MEGAKARYOCYTES, AND PLATELETS. THIS MISSION IS MORE RELEVANT THAN EVER, AS THE INTERDEPENDENCE BETWEEN EACH CELL TYPE BECOMES INCREASINGLY CLEAR, SUCH AS THE ROLE OF MEGAKARYOCYTES IN STEM CELL DEVELOPMENT, AND THE IMPACT OF INFLAMMATION ON MEGAKARYOCYTE GROWTH AND PLATELET PRODUCTION. MORE SPECIFICALLY, THE 2025 CONFERENCE AIMS TO: 1. HIGHLIGHT THE EXTRAORDINARY PROGRESS BEING MADE IN OUR UNDERSTANDING OF PLATELET FUNCTION IN THE CONTEXT OF HEMOSTASIS, THROMBOSIS, AND INHERITED PLATELET DISORDERS. 2. DISCUSS THE LATEST UNPUBLISHED RESEARCH ON THE ENGINEERING OF IN VITRO GENERATED PLATELETS. 3. LINK THE MEGAKARYOCYTE/PLATELET LINEAGE TO IMMUNITY AND INFLAMMATION. 4. REDEFINE THE LINEAGE AND THE BONE MARROW NICHE. 5. EXAMINE STATE-OF-THE-ART STUDIES THAT PUSH THE FIELD INTO NEW DIRECTIONS, INCLUDING MOLECULAR MECHANISMS REGULATING PLATELET PRODUCTION AND VASCULAR INTERACTIONS. TO ENCOURAGE INTERACTION BETWEEN RESEARCHERS, WE HAVE COMBINED MEGAKARYOCYTE AND PLATELET PRESENTATIONS IN THE SAME SESSIONS. IN ADDITION, 10 HIGH RANKING ABSTRACTS WILL BE SELECTED FOR SHORT ORAL PRESENTATIONS THROUGHOUT THE CONFERENCE.

2013 CANNABINOID FUNCTION IN THE CNS GORDON RESEARCH CONFERENCE & GORDON RESEARCH

2013 CATCHMENT SCIENCE GRC/GRS, JUNE 16-21, 2013 AT PROCTOR ACADEMY, ANDOVER, NEW HAMPSHIRE

CAS-CLIMATE: CONFERENCE: 2023 CARBON CAPTURE, UTILIZATION, AND STORAGE GRC AND GRS: TRANSFORMATIVE SCIENCE FOR THE NEW CARBON ECONOMY -THE 2023 GORDON RESEARCH CONFERENCE AND SEMINAR IN CARBON CAPTURE, UTILIZATION, AND STORAGE (GRC- CCUS) WILL PROVIDE A PLATFORM TO DISCUSS TRANSFORMATIVE SCIENTIFIC ADVANCES FOR THE NEW EMERGING CARBON ECONOMY. THE CONFERENCE WILL PROVIDE AN INTEGRATED AND INCLUSIVE PLATFORM WHERE EARLY CAREER RESEARCHERS, ESTABLISHED SCIENTISTS AND ENGINEERS, AND ACADEMICS COME TOGETHER TO DISCUSS NATURAL AND ENGINEERED CARBON MANAGEMENT SOLUTIONS THAT WILL DELIVER MEANINGFUL SOCIETAL AND ECOLOGICAL IMPACTS. THE CONFERENCE IS DESIGNED TO HELP EDUCATE THE PIPELINE OF EMERGING TALENT ON CARBON MANAGEMENT SOLUTIONS. IN THIS CONTEXT, THE ASSOCIATED CARBON CAPTURE, UTILIZATION AND STORAGE GORDON RESEARCH SEMINAR (GRS) WILL PROVIDE A FORUM FOR MENTORING AND TRAINING THE NEXT GENERATION WORKFORCE TO ADVANCE SUSTAINABILITY SOLUTIONS TO CAPTURE, CONVERT, STORE, AND REMOVE CO2 EMISSIONS FROM FLUE GAS EMISSIONS, AIR, AND OCEAN. THE CONFERENCE COMPELLING PROGRAM INCLUDES SPEAKERS AND DISCUSSION LEADERS FROM DIVERSE BACKGROUNDS WITH EXPERTISE RANGING FROM FUNDAMENTAL CHEMICAL INTERACTIONS TO POLICY. THE 2023 GRC-CCUS AND GRS WILL SERVE AS FORUMS TO DISCUSS TRANSFORMATIVE SCIENTIFIC AND TECHNOLOGIES ADVANCES FOR SCALABLE REALIZATION OF CARBON MANAGEMENT SOLUTIONS. THESE EVENTS WILL ADDRESS OPPORTUNITIES AND CHALLENGES AT THE FOREFRONT OF ADVANCING NATURAL AND ENGINEERED CARBON MANAGEMENT SOLUTIONS WHILE CONSIDERING THE EMERGENCE OF LOW COST, RENEWABLE ENERGY RESOURCES, AND THE NEED TO ADDRESS ENVIRONMENTAL JUSTICE CONSIDERATIONS. THE CONFERENCE AND SEMINAR WILL PROVIDE INSIGHTS INTO APPROACHES TO UNLOCK VALUE IN NEGATIVE EMISSIONS TECHNOLOGIES, DELIVER ADDITIONALLY CO-BENEFITS, AND ENSURE PERMANENCE IN STORAGE, ALL WHILE LEARNING FROM TECHNOLOGIES THAT ARE BEING DEPLOYED. THE CONFERENCE AND SEMINAR WILL FOSTER INTERNATIONAL COLLABORATIONS TO TRAIN THE NEXT GENERATION OF RESEARCHERS ON ADVANCING TRANSFORMATIVE CARBON MANAGEMENT SOLUTIONS. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

CANNABINOID FUNCTION IN THE CNS: FROM MOLECULES TO DISEASE MECHANISMS

2018 ENERGETIC MATERIALS GORDON RESEARCH CONFERENCE RESEARCH AREA 1.A.I: CHEMICAL SCIENCES - (3) MOLECULAR STRUCTURE AND DYNAMICS (DR. JAMES K. PARK

2010 GENES & BEHAVIOR

2022 ANGIOTENSIN GRC/GRS - PROJECT SUMMARY THE RENIN ANGIOTENSIN ALDOSTERONE SYSTEM (RAAS) IS A KEY REGULATOR OF CARDIOVASCULAR (CV) FUNCTION, FLUID ELECTROLYTE BALANCE, AND HOMEOSTASIS, AND IT INFLUENCES MANY SYSTEMS INCLUDING THE RENAL, NEUROENDOCRINE, AND IMMUNE SYSTEMS. PERTURBATIONS OF THE RAAS TRIGGER A CASCADE OF EVENTS, INCLUDING GENERATION OF VASOACTIVE MEDIATORS, OXIDATIVE STRESS, INFLAMMATORY RESPONSES, AND TISSUE REMODELING, THUS CONTRIBUTING TO END-ORGAN PATHOLOGY AND DISEASE. IN THE 2022 GRC ON ANG, WE WILL DISCUSS THE MOST RECENT, CUTTING-EDGE DISCOVERIES IN THE FIELD AND SHARE INSIGHTS ON EMERGING NEW AREAS BEYOND THE CV SYSTEM SUCH AS THE ROLE OF THE RAAS IN ADIPOSE BIOLOGY, BONE MARROW REGULATION, LIVER FUNCTION, NEUROCOGNITION, AND IMMUNE RESPONSES. THE CONFERENCE WILL FOCUS ON THE LATEST ADVANCES OF THE RAAS FROM DISCOVERY SCIENCE TO CLINICAL IMPACT. A HIGHLIGHT IN 2022 WILL BE THE CELEBRATION OF 22 YEARS OF THE DISCOVERY OF ACE2. ACE2 IS A MULTIFUNCTIONAL PROTEIN, THAT NOT ONLY IS CV PROTECTIVE BY GENERATING ANG-(1-7) AND ANG-(1-9) FROM ANG II AND ANG I RESPECTIVELY, BUT IT IS ALSO, TISSUE INJURIOUS BY ACTING AS THE RECEPTOR FOR THE SARS-COV-2, THE ETIOLOGIC AGENT OF THE CURRENT WORLDWIDE COVID-19 PANDEMIC. THE ENIGMAS OF ACE2 AS A KEY ENZYME IN THE PROTECTIVE ARM OF THE RAAS WILL BE A HIGHLIGHT. THE ROLE OF ACE2 AS A MAJOR MEDIATOR AND POTENTIAL THERAPEUTIC TARGET IN COVID-19 WILL BE DEBATED ALONG WITH THE CONTROVERSIES ON THE PROGRESSION OF COVID-19 INFECTION AND LONG-TERM OUTCOMES IN POPULATIONS TREATED WITH ACE INHIBITORS AND/OR ANGIOTENSIN RECEPTOR BLOCKERS. THE 2022 GRC ON ANG WILL FURTHER FEATURE NOVEL TOPICS INCLUDING SEX-DIFFERENCES IN THE REGULATION AND CHANGES OF THE RAAS DURING THE LIFE COURSE (FETAL PROGRAMMING, KIDNEY DEVELOPMENT, AND AGING) WILL BE FURTHER ADDRESSED. IN LINE WITH PRECISION MEDICINE BEING THE NEXT FRONTIER IN CLINICAL MEDICINE, THE MEETING WILL ALSO HIGHLIGHT NEW ADVANCES IN THE PHARMACOGENOMICS, PROTEOMICS, AND METABOLOMICS OF THE RAAS IN HUMAN DISEASES. PRECEDING THE GRC, WE WILL HAVE THE 2022 GORDON RESEARCH SEMINAR (GRS), A SPECIAL FORUM FOR GRADUATE STUDENTS, POSTDOCTORAL FELLOWS, EARLY CAREER RESEARCHERS AND OTHER JUNIOR SCIENTISTS TO PRESENT AND EXCHANGE NEW DATA AND CUTTING-EDGE IDEAS. THE 2022 GRS WILL FOCUS ON RECENT ADVANCES IN RAAS STUDIES BEYOND THE CLASSICAL PARADIGMS, INCLUDING NEW FUNCTIONS OF RECEPTORS FROM THIS SYSTEM AND PROVIDING TRAINEES WITH AN ENHANCED UNDERSTANDING OF CURRENT TOOLS TO AID THEIR RESEARCH, AND COVER A WIDE RANGE OF TOPICS INCLUDING THE IMMUNE SYSTEM, SEX DIFFERENCES AND AGING. ADDITIONALLY, THE MENTORSHIP SESSIONS WILL ADDRESS THE INTERPLAY BETWEEN ACADEMIA AND INDUSTRY AND DISCUSS APPROACHES TO TRANSLATE SCIENTIFIC DISCOVERIES TO THE CLINIC AND HOW TO OPTIMIZE IMPACT. THE AIMS ARE ALIGNED WITH THE NHLBI, NIDDK AND NIAID MISSIONS AND INITIATIVE AND THE SCIENTIFIC THEMES THAT WILL BE COVERED ARE OF DIRECT RELEVANCE TO THESE INSTITUTES. NIH FUNDS REQUESTED WILL HELP ATTRACT YOUNG INVESTIGATORS AND TRAINEES, INCLUDING FROM UNDERREPRESENTED GROUPS WITH LIMITED OPPORTUNITIES TO JOINT TOP NATIONAL AND INTERNATIONAL EXPERTS IN THE RAAS FOR NETWORKING AMONG RESEARCHERS, CLINICIANS, YOUNG INVESTIGATORS AND TRAINEES.

2017 CILIA, MUCUS AND MUCOCILIARY INTERACTIONS GORDON RESEARCH CONFERENCE & GORDON RESEARCH SEMINAR

2017 UNDERGRADUATE BIOLOGY EDUCATION RESEARCH (UBER): IMPROVING DIVERSITY, EQUITY, AND LEARNING GORDON RESEARCH CONFERENCE

2024 VISUAL SYSTEM DEVELOPMENT GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR - PROJECT SUMMARY THE 2024 GORDON RESEARCH CONFERENCE (GRC) AND GORDON RESEARCH SEMINAR (GRS) ON VISUAL SYSTEM DEVELOPMENT ARE A PAIRED SET OF BIENNIAL MEETINGS THAT BRING TOGETHER INVESTIGATORS STUDYING DEVELOPMENT, DISEASE AND EVOLUTION OF THE VISUAL SYSTEM. OVER THE YEARS, THESE MEETINGS HAVE PROVIDED AN EXCITING AND UNIQUE FORUM IN WHICH TO EXPLORE THE SIMILARITIES AND DIFFERENCES UNDERLYING VISUAL SYSTEM DEVELOPMENT AND FUNCTION ACROSS A BROAD RANGE OF SPECIES. THE GOAL OF THESE MEETINGS IS TO FOSTER AN APPRECIATION OF COMMON PRINCIPLES THAT MEDIATE THE CONSTRUCTION AND FUNCTION OF THE VISUAL SYSTEM IN DIVERSE ORGANISMS, AND TO SHARE THE LATEST EXCITING NEW IDEAS AND FINDINGS ON THIS TOPIC. BY INCLUDING SESSIONS THAT HIGHLIGHT EMERGING TOPICS WITH TRANSLATIONAL IMPACT, SUCH AS “RETINAL REGENERATION AND REPAIR”, “DEVELOPMENT AND DYSFUNCTION OF THE PRIMATE RETINA” AND “RETINAL DISEASE AND AGING”, THE MEETING WILL ALSO EXPAND ITS SCOPE AND STIMULATE CROSS-TALK BETWEEN DEVELOPMENTAL BIOLOGISTS AND INVESTIGATORS FOCUSED ON TRANSLATIONAL ASPECTS OF VISION SCIENCE. THE GRS PROVIDES A UNIQUE PLATFORM FOR STUDENTS AND POSTDOCTORAL RESEARCH FELLOWS IN THE VISUAL RESEARCH FIELD TO SHARE CURRENT, UNPUBLISHED RESEARCH AMONGST THEIR PEERS. THE FORMAT OF THE GRC AND GRS MEETINGS PROVIDES A HIGHLY INTERACTIVE AND STIMULATING VENUE FOR CROSS- FERTILIZATION OF IDEAS AND DEVELOPING NEW COLLABORATION. THE VISUAL SYSTEM DEVELOPMENT GRC HAS ESTABLISHED A REPUTATION AS THE LEADING CONFERENCE IN ITS FIELD AND IS THE ONLY MEETING ON THE TOPIC THAT BRINGS TOGETHER VISION RESEARCHERS WORKING ON THE FULL RANGE OF EXPERIMENTAL SYSTEMS IN THE FIELD, RANGING FROM DROSOPHILA TO HUMAN. THE CURRENT PROPOSAL REQUESTS FUNDS TO HELP DEFRAY CONFERENCE FEES FOR ATTENDEES AT BOTH MEETINGS. THE VISUAL SYSTEM GRC AND GRS WILL FEATURE SCIENTISTS AT THE CUTTING EDGE OF THE FIELD, WITH CAREFUL ATTENTION TAKEN TO ENSURE GENDER, ETHNIC, AND GEOGRAPHIC DIVERSITY, AND TO INCLUDE SCIENTISTS AT ALL STAGES OF THEIR CAREERS.

2012 CORNEA, BIOLOGY & PATHOBIOLOGY GRC

2014 THE AUDITORY SYSTEM GORDON RESEARCH CONFERENCE & GORDON RESEARCH SEMINAR

2024 INTERMEDIATE FILAMENTS GORDON RESEARCH CONFERENCE AND SEMINAR - SUMMARY INTERMEDIATE FILAMENT (IF) PROTEINS ARE ENCODED BY OVER 70 DISTINCT GENES, PLACING THEM AMONG THE LARGEST GENE FAMILIES IN HUMANS. MEMBERS OF THE IF PROTEIN FAMILY HAVE DIVERSE FUNCTIONS IN VIRTUALLY ALL CELL TYPES. THEY SERVE AS CRITICAL COMPONENTS OF THE CYTOSKELETON AND NUCLEOSKELETON AND ACT AS SENSORS, MODULATORS, AND INTEGRATORS OF OTHER KEY STRUCTURAL AND REGULATORY PROTEINS. MUTATIONS IN GENES ENCODING IF PROTEINS CAUSE A WIDE RANGE OF DISEASES, INCLUDING SKIN DISEASES, MUSCULAR DYSTROPHY, CARDIOMYOPATHY, PREMATURE AGING SYNDROMES, AND NEURODEGENERATIVE DISORDERS. ABNORMAL ASSEMBLIES OF IFS ARE HALLMARKS OF AND BIOMARKERS FOR CANCER NEURODEGENERATIVE DISORDERS, AND LIVER DISEASES. GIVEN THE DIVERSE FUNCTIONS OF IF PROTEINS, THEIR INTERACTIONS WITH OTHER CELLULAR COMPONENTS, AND THEIR DISEASE RELEVANCE, CLOSE COLLABORATIONS BETWEEN BASIC RESEARCHERS AND TRANSLATIONAL INVESTIGATORS SPANNING MULTIPLE DISCIPLINES ARE NECESSARY TO OVERCOME CURRENT CHALLENGES IN THE FIELD. BRINGING TOGETHER SUCH DIVERSE SCIENTISTS WILL PROVIDE NEW INSIGHTS INTO THE PHYSIOLOGICAL FUNCTIONS OF IFS AND FOSTER THE DEVELOPMENT OF NOVEL THERAPEUTIC APPROACHES FOR IF-RELATED DISEASES. TOWARDS THIS GOAL, THIS APPLICATION REQUESTS FUNDS TO SUPPORT THE JUNE 2024 GORDON RESEARCH CONFERENCE (GRC) AND GORDON RESEARCH SEMINAR (GRS) ON IFS TO BE HELD AT REY DON JAIME GRAND HOTEL, LOCATED JUST OUTSIDE BARCELONA IN CASTELLDEFELS, SPAIN. WE HAVE ORGANIZED A STIMULATING PROGRAM OF SCIENTIFIC SESSIONS IN AN ENVIRONMENT THAT IS CONDUCIVE TO CONCENTRATED DISCUSSION AND DEBATE, AS WELL AS INFORMAL INTERACTIONS AND NETWORKING. THE SPEAKERS AND OTHER ATTENDEES WILL BE ESTABLISHED, MID-CAREER, AND EARLY-CAREER SCIENTISTS AS WELL AS STUDENTS AND TRAINEES FROM DIVERSE BACKGROUNDS REPRESENTING MULTIPLE DISCIPLINES. AIM 1 IS TO PROVIDE AN INTERDISCIPLINARY FORUM FOR THE DISCUSSION OF THE BEST AND MOST RECENT RESEARCH ON IFS, AND THEIR RELATIONSHIP TO CELL PHYSIOLOGY AND DISEASE. AIM 2 IS TO HIGHLIGHT NOVEL SCIENTIFIC THEMES RELEVANT TO IF RESEARCH, WHICH WILL BE ACCOMPLISHED BY INCLUDING NOVEL SCIENTIFIC SESSIONS AND INVITING SEVERAL SPEAKERS OUTSIDE OF THE TRADITIONAL IF COMMUNITY TO PROMOTE NEW IDEAS AND APPROACHES. AIM 3 IS TO PROMOTE FORMAL AND INFORMAL SCIENTIFIC EXCHANGES ON IF BIOLOGY BETWEEN INVESTIGATORS ACROSS THE WHOLE CAREER SPECTRUM. GRADUATE STUDENTS AND POSTDOCTORAL RESEARCHERS WILL ALSO BE ABLE TO PARTICIPATE IN THE GRS IMMEDIATELY PRIOR TO THE GRC. THE GRS IS RUN SOLELY BY GRADUATE STUDENTS AND POSTDOCTORAL SCIENTISTS STUDYING IFS. TO ENHANCE INTERACTIONS, EACH DAY OF THE GRC AND GRS WILL PROVIDE NUMEROUS OPPORTUNITIES FOR INFORMAL EXCHANGES AMONG PARTICIPANTS, INCLUDING SHARED MEALS, FREE AFTERNOONS, POSTER SESSIONS, AND EVENING SOCIAL TIMES. THE BROAD LONG-TERM OBJECTIVES OF THE GRC AND GRS ARE TO GROW THE IF COMMUNITY AND TO PROVIDE FORUMS FOR THE EXCHANGE OF IDEAS AMONG SCIENTISTS AT ALL CAREER STAGES INTERESTED IN IFS, A FAMILY OF PROTEINS THAT ARE UNDERSTUDIED DESPITE THEIR SIGNIFICANT IMPACT ON MAJOR AREAS OF PUBLIC HEALTH.

2016 NEUROBIOLOGY OF BRAIN DISORDERS GORDON RESEARCH CONFERENCE AND SEMINAR

2009 OXIDATIVE STRESS AND DISEASE GORDON RESEARCH CONFERENCE

2022 OCEAN MIXING GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR

2009 PHYSICAL METALLURGY: INTEGRATING COMPUTATIONAL MATERIALS SCIENCE AND ENGINEERING GORDON CONFERENCE

NEW; TITLE: 2011 PLANT METABOLIC ENGINEERING GRC/GRS, JULY 24-29, 2011; PI: NATALIA DOUDAREVA

2022 OCEAN MIXING GORDON RESEARCH CONFERENCE AND SEMINAR

CONFERENCE: 2025 ENVIRONMENTAL NANOTECHNOLOGY GRC -THIS NSF AWARD SUPPORTS THE 2025 ENVIRONMENTAL NANOTECHNOLOGY GORDON RESEARCH CONFERENCE THAT WILL BE HELD IN NEWRY, MAINE JUNE 1-6,2025. THIS CONFERENCE WILL EXPLORE CURRENT, UNPUBLISHED, STATE-OF-THE ART RESEARCH ON THE APPLICATIONS OF NANOTECHNOLOGY FOR 1) WATER AND FOOD PRODUCTION, 2) ENERGY DEVELOPMENT; AND 3) PROTECTION OF HUMAN AND ENVIRONMENTAL HEALTH. OPPORTUNITY EXISTS TO CREATE NOVEL MATERIALS BASED ON THE ENHANCED CATALYTIC, OPTICAL, MAGNETIC AND ELECTRICAL PROPERTIES OF NANOMATERIALS ACROSS A VARIETY OF SECTORS FROM HUMAN HEALTH TO WATER PURIFICATION, REMEDIATION, SENSING, ENERGY PRODUCTION, AND SECURITY. CHALLENGING AND REWARDING WORK MUST BE DONE TO SEIZE THIS OPPORTUNITY WHILE DESIGNING NANOTECHNOLOGY WITH THE ENVIRONMENT IN MIND. THE CONFERENCE ATTENDEES WILL INCLUDE ENVIRONMENTAL ENGINEERS, ENVIRONMENTAL SCIENTISTS, CHEMISTS, POLICYMAKERS, AND OTHER STAKEHOLDERS. ATTENDEES WILL EXCHANGE IDEAS AND PROMOTE THE DEVELOPMENT OF NEW CONVERGENT RESEARCH CONCEPTS FOCUSED ON THE ENVIRONMENTAL APPLICATIONS OF NANOTECHNOLOGY. FORMAL AND INFORMAL DISCUSSIONS FACILITATED BY ATTENDANCE AT THIS CONFERENCE WILL PROMOTE FURTHER DEVELOPMENT OF THE ENVIRONMENTAL NANOTECHNOLOGY FIELD. FACE-TO-FACE INTERACTIONS BETWEEN CONFERENCE ATTENDEES WILL FACILITATE TRANSDISCIPLINARY RESEARCH ACTIVITIES. NSF FUNDING WILL ENABLE THE CONFERENCE ORGANIZER TO PROVIDE TRAVEL GRANTS TO INVITED SPEAKERS, POST-DOCTORAL SCHOLARS, GRADUATE STUDENTS, AND JUNIOR FACULTY. THE SPECIFIC OBJECTIVES OF THE CONFERENCE ARE TO 1) PROVIDE A FORUM FOR GENERATIONS OF IDEAS REGARDING THE USE OF NANOTECHNOLOGY TO BENEFIT THE ENVIRONMENT AND SOCIETY THROUGH TECHNOLOGY DEVELOPMENT, AND 2) TO GENERATE IDEAS AND RESEARCH PROGRAMS THAT WILL FOMENT PREVENTION OF POTENTIAL ENVIRONMENTAL HARMS THAT MAY RESULT FROM INDISCRIMINATE DEVELOPMENT AND USE OF NANOTECHNOLOGY. THESE OBJECTIVES WILL BE ADDRESSED IN TECHNICAL SESSIONS, VIA SUBMITTED POSTERS, AND THROUGH COLLABORATIVE ACTIVITIES. THIS AWARD WILL ENABLE THE CONFERENCE ORGANIZER TO PROVIDE TRAVEL GRANTS TO INVITED SPEAKERS, POST-DOCTORAL SCHOLARS, GRADUATE STUDENTS, AND JUNIOR FACULTY. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

2022 GORDON RESEARCH CONFERENCE ON OCEAN MIXING: THE IMPACT OF OCEAN MIXING ON THE EARTH, OCEAN AND ATMOSPHERE SYSTEMS, CLIMATE AND SOCIETY -THIS PROJECT PROVIDES PARTIAL SUPPORT FOR THE 2022 GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR ON OCEAN MIXING. TURBULENT MIXING RESULTS FROM COMPLEX AND CHAOTIC MOTIONS THAT SPAN A LARGE RANGE OF SPATIAL AND TEMPORAL SCALES. AS SUCH, IT IS PARTICULARLY CHALLENGING TO MEASURE AND MODEL, YET IT HAS VAST AND IMPORTANT CONSEQUENCES. IN THE OCEAN, TURBULENT MIXING CONTROLS TRANSPORT OF HEAT, FRESHWATER, DISSOLVED GASSES, AND POLLUTANTS. IT IS CRUCIAL FOR OCEAN BIOLOGY BECAUSE IT BOTH DETERMINES THE FLOW FIELD FOR THE SMALLEST PLANKTON, AND IT SETS LARGE-SCALE GRADIENTS OF NUTRIENT AVAILABILITY. IT IS ALSO CENTRAL TO UNDERSTANDING THE ENERGETICS OF THE OCEAN AND REDUCING THE UNCERTAINTIES IN GLOBAL CIRCULATION AND CLIMATE MODELS: RECENT WORK HAS SHOWN THAT THE SPATIAL AND TEMPORAL NON-HOMOGENEITY IN DEEP-OCEAN MIXING MAY PLAY A CRITICAL ROLE IN CLIMATE; UNDERSTANDING THE PHYSICS THAT DRIVES THE DISTRIBUTION OF DEEP-OCEAN MIXING INTENSITY IS CRITICAL. YET EVEN AFTER A HALF A CENTURY OF EFFORTS TO UNDERSTAND ITS GLOBAL DISTRIBUTION, OBSERVATIONS ARE STILL SPARSE; A VARIETY OF DIRECT AND INDIRECT METHODS ARE STILL NEEDED TO CHARACTERIZE THE DYNAMICAL PROCESSES THAT LEAD TO TURBULENCE, AND INFERENCES OF MIXING FROM LARGER SCALE BUDGETS. AS SUCH, THE PHYSICS OF OCEAN MIXING IS ACTIVELY STUDIED USING A VARIETY OF OBSERVATIONAL TECHNIQUES (DIRECT MEASURE OF VELOCITY AND TEMPERATURE FLUCTUATIONS AT THE SMALLEST (MM) SCALES, INFERENCES FROM LARGE-SCALE TURBULENT OVERTURNS, OBSERVATIONS OF NET MIXING BY PURPOSEFUL DYE RELEASE) NUMERICAL AND THEORETICAL APPROACHES, AS WELL AS LABORATORY EXPERIMENTS. FINALLY, THE CONSEQUENCES OF MIXING FOR LARGER SCALE CLIMATE MODELS (WHICH DO NOT DIRECTLY RESOLVE MIXING) ARE ADDRESSED BY TURNING DYNAMICAL INSIGHTS OF THE PREVIOUSLY MENTIONED WORK INTO PRACTICAL PARAMETERIZATIONS. AS A CONCRETE EXAMPLE, USING DIFFERENT MIXING SCHEMES IN NUMERICAL CLIMATE MODELS CHANGES PREDICTED TROPICAL OCEAN TEMPERATURES BY MORE THAN A DEGREE AND PREDICTED SEA LEVEL RISE BY MORE THAN 30 CM. MIXING IS ONE OF THE GREATEST SOURCES OF UNCERTAINTY PLAGUING TODAY?S MODELS WITH IMPACT OF GREAT SOCIETAL RELEVANCE. A REGULARLY HELD GRC ON OCEAN MIXING PROVIDES A NEEDED FORUM TO IMPROVE THE BROADER COMMUNITY?S UNDERSTANDING OF TURBULENT MIXING IN THE OCEAN, AND WITH IT A VARIETY OF DEEP AND BROAD IMPLICATIONS FOR EVERYTHING FROM CLIMATE CHANGE TO GLOBAL NUTRIENT PATTERNS THAT UNDERLIE OUR FISHERIES. THE GRC FORMAT ENCOURAGES PRECISELY THE SORT OF INTERDISCIPLINARY THINKING AND COLLABORATION THAT IS SO VITAL TO ADDRESSING THESE SOCIETAL ISSUES. THIS GRC, IN PARTICULAR, HELPS OUR SCIENTIFIC COMMUNITY BE THE MOST VIBRANT & INCLUSIVE IT CAN BE. THE OCEAN MIXING HAS HISTORICALLY SUFFERED FROM POOR DIVERSITY, WHICH, WHILE IMPROVED IN RECENT YEARS, STILL NEEDS AN INFLUX OF NEW PEOPLE, A BROADENING OF TIES AMONGST DOMESTIC AND INTERNATIONAL COLLABORATORS, AND INCREASED INTERDISCIPLINARY INTERACTIONS. NSF SUPPORT WILL EXPLICITLY BE USED TO EXPAND THE DEMOGRAPHIC, PROFESSIONAL AND GEOGRAPHIC DIVERSITY OF PARTICIPANTS BY SUPPORTING ATTENDANCE OF UNDER-REPRESENTED AND UNDER-RESOURCED GROUPS WHO STAND TO BENEFIT FROM THE INTELLECTUAL ENVIRONMENT AND NETWORKING OPPORTUNITIES OF THE GRC FORMAT. THE PURPOSE AND SCOPE OF THIS GORDON RESEARCH CONFERENCE IS TO PROVIDE A FORUM FOR DISCUSSION OF THE RAPIDLY EVOLVING FIELD OF OCEAN MIXING. EMPHASIS IS THREEFOLD: OBSERVATIONS OF MIXING IN THE WORLD, NEW INSIGHTS INTO DYNAMICS THAT CONTROL MIXING RATES, AND IMPACTS OF MIXING ON REGIONAL AND GLOBAL CIRCULATION AND BUDGETS. THE LATTER TWO INCLUDE DEVELOPMENT OF PARAMETERIZATIONS TO TURN DYNAMICAL INSIGHTS INTO USEFUL THINGS TO INCLUDE IN REGIONAL MODELS AND GLOBAL NUMERICAL CLIMATE MODELS. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

SUPPORT FOR THE 2018 GORDON RESEARCH CONFERENCE ON ENVIRONMENTAL SCIENCES: WATER TO HELD JUNE 24-29, 2018 IN HOLDERNESS, NH

2017 CLIMATE ENGINEERING GORDON RESEARCH CONFERENCE (GRC) TO BE HELD ON JULY 23-28, 2017 AT SUNDAY RIVER IN NEWRY, ME

2016 GORDON RESEARCH CONFERENCE ON ENVIRONMENTAL SCIENCES: WATER: OPPORTUNITIES FOR AQUATIC SCIENCES TO IMPACT A CHANGING WORLD

2011 INTERIOR OF THE EARTH GORDON RESEARCH CONFERENCE

2026 PLASMINOGEN ACTIVATION AND EXTRACELLULAR PROTEOLYSIS GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR - THE 2026 GORDON RESEARCH CONFERENCE (GRC) ON PLASMINOGEN ACTIVATION AND EXTRACELLULAR PROTEOLYSIS AND THE ASSOCIATED GORDON GRADUATE RESEARCH SEMINAR (GRS) ARE PAIRED CONFERENCES HELD SEQUENTIALLY AT THE SAME LOCATION IN VENTURA, CA. THE GRS WILL TAKE PLACE ON FEBRUARY 7-8, AND THE GRC ON FEBRUARY 8-13, 2026. THE GRC HAS BEEN HELD CONTINUOUSLY EVERY TWO YEARS SINCE 1990 AND ENJOYS AN OUTSTANDING INTERNATIONAL REPUTATION. IN THIS 20TH GRC, WE WILL DISCUSS BREAKTHROUGH FINDINGS IN PLASMINOGEN ACTIVATION AND EXTRACELLULAR PROTEOLYSIS IN AREAS SUCH AS VASCULAR BIOLOGY, CENTRAL NERVOUS SYSTEM FUNCTION AND DYSFUNCTION, TRAUMA, TISSUE HOMEOSTASIS AND REGENERATION, HEMATOPOIESIS, ANGIOGENESIS, STEM CELL BIOLOGY, METABOLISM AND OBESITY, TUMOR BIOLOGY, CARDIOVASCULAR FUNCTION, AND AGING. FOR THE 2026 GRC MEETING, EMPHASIS WILL BE PLACED ON BRINGING TOGETHER THE BIOMEDICAL PRACTICE WITH THE BIOLOGY OF PLASMINOGEN ACTIVATION AND OTHER EXTRACELLULAR PROTEASES, THEIR EFFECTORS AND ASSOCIATED PATHWAYS, AS THEY ARE RELEVANT TO MULTIPLE DISEASES AND DISORDERS. BASIC AND PHYSICIAN SCIENTISTS WILL DISCUSS THE RELEVANT CLINICAL NEEDS AND POSSIBLE THERAPEUTIC STRATEGIES THAT CAN BE ACCOMMODATED USING THE KNOWLEDGE GENERATED THROUGH BASIC SCIENCE. EARLY AND MID-CAREER INVESTIGATORS IN THE FIELD WILL HAVE THE CHANCE TO PRESENT AND DISCUSS THEIR NEW AND EXCITING FINDINGS ALONGSIDE SENIOR, ESTABLISHED RESEARCHERS. BASIC RESEARCH, TECHNOLOGICAL ADVANCES, AND CUTTING-EDGE THERAPEUTIC APPROACHES IN THE FIELD OF EXTRACELLULAR PROTEASES WILL BE DEBATED AND DISCUSSED, WITH THE EXPECTATION THAT NEW COLLABORATIONS AND SCIENTIFIC DISCOVERIES WILL DEVELOP FROM THESE IN-PERSON INTERACTIONS. RESEARCH THEMES OF THE 2026 GRC ON PLASMINOGEN ACTIVATION AND EXTRACELLULAR PROTEOLYSIS WILL CAPTURE THE MOST EXCITING AREAS OF CONTEMPORARY CUTTING-EDGE RESEARCH IN THE FIELD. EMERGING ROLES FOR MOLECULES OF THE FIBRINOLYTIC SYSTEM AND OTHER PROTEASES IN PATHOLOGIC SETTINGS SUCH AS CANCER, CARDIO- AND CEREBROVASCULAR DISEASE, METABOLIC COMPLICATIONS, AGING, TRAUMA, AND NEUROLOGICAL DISEASES WILL BE PRESENTED. THE DEVELOPMENT AND APPLICATION OF NOVEL TECHNOLOGIES IN THE FIELD WILL ALSO BE DISCUSSED. EACH SESSION WILL INCLUDE A DISCUSSION OF HOW BASIC RESEARCH IN OUR FIELD CAN HELP CONQUER HUMAN DISEASE. THE ASSOCIATED GRS WILL PROVIDE A VENUE FOR PRE- AND POSTDOCTORAL TRAINEES TO DISCUSS THEIR RESEARCH IN A COLLABORATIVE AND STIMULATING ENVIRONMENT TO HELP BUILD THEIR INFORMAL NETWORK OF PEERS AND COLLEAGUES. WE EXPECT THAT THE 2026 PLASMINOGEN ACTIVATION AND EXTRACELLULAR PROTEOLYSIS GRC AND GRS WILL BRING TOGETHER A GROUP OF HIGHLY MOTIVATED AND INTERACTIVE PARTICIPANTS WITH DIFFERENT SCIENTIFIC BACKGROUNDS TO ENGAGE IN INTENSIVE DISCUSSIONS AT THE FRONTIER OF RESEARCH RELATED TO THE PLASMINOGEN ACTIVATION SYSTEM AND ASSOCIATED EXTRACELLULAR PROTEASES IN AN “OFF-THE-RECORD” FASHION. THE INFORMATION GAINED FROM THIS MEETING WILL ADVANCE THE PLASMINOGEN ACTIVATION/EXTRACELLULAR PROTEOLYSIS FIELD BY TEACHING US ABOUT ADDITIONAL DIRECT AND NUANCED ROLES FOR THESE PROTEINS, WHICH SHOULD IN TURN STIMULATE THE DEVELOPMENT OF NEW APPLICATIONS AND STRATEGIES TO IMPROVE THE DIAGNOSIS, PREVENTION, AND TREATMENT OF A WIDE RANGE OF DISEASES.

2026 LYSOSOMES AND ENDOCYTOSIS GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR - PROJECT SUMMARY NIH SUPPORTED RESEARCH AIMS TO ADVANCE OUR UNDERSTANDING OF BIOLOGICAL SYSTEMS, IMPROVE THE CONTROL OF DISEASE, AND ENHANCE HEALTH. IT IS WELL-RECOGNIZED THAT CONNECTING INVESTIGATORS WITH COMPLEMENTARY EXPERTISE’S IN FUNDAMENTAL CELL BIOLOGY, BIOCHEMISTRY, GENETICS, STATE OF THE ART IMAGING WITH THOSE DEVELOPING AVENUES FOR THE TREATMENT OF DISEASE ARE ESSENTIAL TO GET EFFECTIVE ADVANCES. THIS GRANT PROPOSAL SEEKS SUPPORT FOR THE 2026 GORDON RESEARCH CONFERENCE (GRC) AND ASSOCIATED GORDON RESEARCH SEMINAR (GRS) ON LYSOSOMES AND ENDOCYTOSIS, WITH A CENTRAL THEME OF “ENDOSOMES AND LYSOSOMES IN ACTION ACROSS CELLS, TISSUES AND DISEASE STATES”. AS THE FIELD OF LYSOSOMES AND ENDOCYTOSIS EVOLVES WITH INCREASING RESEARCH IN THIS AGING RELATED TOPICS, THE 2026 MEETING WILL PLACE AN IMPORTANT EMPHASIS ON NEURODEGENERATIVE DISEASE, SPECIFICALLY ALZHEIMER DISEASE AND RELATED AGING DISORDERS. EXPLORING AT THE CELLULAR, MOLECULAR AND STRUCTURAL LEVELS HOW DEFECTS IN LYSOSOMAL AND ENDOCYTIC PROCESSES CONTRIBUTE TO DISEASE ONSET AND PROGRESSION ARE ESSENTIAL FUNDAMENTS FOR THERAPEUTICAL INTERVENTION. ENDOSOMES AND LYSOSOMES ARE CRITICAL COMPONENTS OF THE ENDOMEMBRANE SYSTEM, ORCHESTRATING ESSENTIAL CELLULAR PROCESSES INCLUDING CARGO SORTING, DEGRADATION, MEMBRANE TRAFFICKING, AND SIGNALING. THEIR COORDINATED ACTIVITY ENSURES PROPER CELLULAR HOMEOSTASIS AND ADAPTABILITY ACROSS A WIDE RANGE OF CELL TYPES AND TISSUE ENVIRONMENTS. EMERGING EVIDENCE HIGHLIGHTS THEIR DYNAMIC AND CONTEXT-DEPENDENT ROLES IN DEVELOPMENT, IMMUNITY, METABOLISM, AND CELL FATE DETERMINATION. NOTABLY, DYSREGULATION OF ENDO-LYSOSOMAL PATHWAYS IS INCREASINGLY RECOGNIZED AS A CENTRAL CONTRIBUTOR TO THE PATHOGENESIS OF NUMEROUS DISEASES, INCLUDING NEURODEGENERATIVE DISORDERS, CANCERS, METABOLIC SYNDROMES, AND LYSOSOMAL STORAGE DISEASES. THE GRC WILL BRING TOGETHER INTERNATIONALLY RECOGNIZED EXPERTS AND EMERGING SCIENTISTS TO PRESENT UNPUBLISHED DATA, STIMULATE DISCUSSION, AND DEVELOP NEW COLLABORATIONS. THE GRS, HELD PRIOR TO THE MAIN CONFERENCE, WILL OFFER A FOCUSED ENVIRONMENT FOR TRAINEES AND JUNIOR RESEARCHERS TO PRESENT THEIR WORK AND BUILD PROFESSIONAL NETWORKS TO BOOST THEIR CAREERS.

2026 MEMBRANE TRANSPORT PROTEINS GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR - PROJECT SUMMARY THE 2026 GORDON RESEARCH CONFERENCE ON MEMBRANE TRANSPORT PROTEINS, “THE DYNAMIC MEMBRANE TRANSPORTER: GATEWAYS TO HEALTH & DISEASE,” WILL CONVENE ~200 INVESTIGATORS FROM ACADEMIA, INDUSTRY, AND MEDICINE AT THE RENAISSANCE TUSCANY IL CIOCCO, JUNE 14–19 (TRAINEE-LED GRS, JUNE 13–14). THIS LOCATION FACILITATES PARTICIPATION BY A BROAD INTERNATIONAL COMMUNITY OF SCIENTIST, TRAINEES, AND EARLY-CAREER SCIENTISTS WORKING ON MEMBRANE TRANSPORT PROTEINS. THE BROADER SCIENTIFIC EXCHANGE DIRECTLY BENEFITS PUBLIC HEALTH IN THE UNITED STATES BY SPEEDING ADVANCES IN THE UNDERSTANDING OF DISEASE MECHANISMS, THE DEVELOPMENT OF NEW DRUGS, AND THE IDENTIFICATION OF PROMISING THERAPEUTIC STRATEGIES. IT ALSO ENSURES THAT THE UNITED STATES RESEARCHERS REMAIN FULLY ENGAGED WITH THE DISCOVERIES, TECHNOLOGIES, AND RESEARCH SHAPING DRUG DISCOVERY IN THIS IMPORTANT FIELD. MEMBRANE TRANSPORTERS COMPRISE ROUGHLY 10 % OF THE HUMAN GENOME, YET FEWER THAN 4 % ARE CLINICALLY EXPLOITED, DESPITE THEIR CENTRAL ROLES IN PREVALENT DISORDERS, INCLUDING AUTISM, DEPRESSION, ADHD, ADDICTION, AND DIABETES, AND IN RARE DISEASES SUCH AS CHRISTIANSON SYNDROME AND MUCOVISCIDOSIS. BREAKTHROUGHS IN CRYO-EM, AI-DRIVEN STRUCTURE PREDICTION, LIVE-CELL BIOSENSORS, AND HUMAN-DERIVED DISEASE MODELS NOW MAKE IT POSSIBLE TO TRANSLATE FUNDAMENTAL TRANSPORTER BIOLOGY INTO FIRST-IN-CLASS THERAPEUTICS, CREATING A TIMELY NEED FOR A FORUM THAT SEAMLESSLY LINKS MOLECULAR MECHANISMS TO CLINICAL APPLICATIONS. THE PROGRAM’S NINE THEMED SESSIONS AND TWO PLENARY LECTURES DELIBERATELY PAIR STRUCTURAL AND MECHANISTIC DISCOVERIES WITH PRECLINICAL AND CLINICAL PERSPECTIVES, COVERING TOPICS FROM VESICULAR NEUROTRANSMITTER LOADING AND BLOOD–BRAIN-BARRIER GATEWAYS TO ABC/OCT1-MEDIATED DRUG DISPOSITION. INTERWOVEN “TECHNOLOGY SPOTLIGHT” TALKS AND “REALITY-CHECK” PANELS WILL SHOWCASE STATE-OF-THE-ART METHODS WHILE CANDIDLY ADDRESSING THEIR LIMITATIONS, ESTABLISHING RIGOROUS, FIELD-WIDE STANDARDS. A 1.5-DAY, TRAINEE-RUN GORDON RESEARCH SEMINAR, ANCHORED BY KEYNOTE MENTORS DRS. SARA JONES AND WALTER BORON, PLUS MENTORING INNOVATIONS SUCH AS “SCIENTIST SPEED-DATING” LUNCHES AND THE FORUM BREAKING THE MOLD: OVERCOMING BARRIERS TO CAREER ADVANCEMENT WILL FOSTER AN INCLUSIVE, SUPPORTIVE ENVIRONMENT THAT CULTIVATES THE NEXT GENERATION OF TRANSPORTER SCIENTISTS. GUIDED BY THREE SPECIFIC AIMS, CATALYZING TRANSLATIONAL SCIENCE, ELEVATING RIGOR AND REPRODUCIBILITY, AND BUILDING A GLOBAL WORKFORCE, THE CONFERENCE IS POISED TO REVEAL NEW TRANSPORTER LIGANDS, BIOMARKERS, AND DRUG-DELIVERY STRATEGIES; TO DISSEMINATE BEST-PRACTICE METHODOLOGIES; AND TO LAUNCH ENDURING MENTORSHIP NETWORKS. BY UNITING SILOED DISCIPLINES IN A CONFIDENTIAL, OFF-THE-RECORD ENVIRONMENT THAT ENCOURAGES PRESENTATION OF UNPUBLISHED DATA, THE 2026 GRC WILL ACCELERATE TRANSPORTER-BASED SOLUTIONS FOR SOME OF TODAY’S MOST URGENT UNMET MEDICAL NEEDS.

2019 CHEMICAL OCEANOGRAPHY GORDON RESEARCH CONFERENCE: DISCOVERING CHEMICAL PROCESSES AND MECHANISMS IN A CHANGING OCEAN

2020 CORNEA AND OCULAR SURFACE BIOLOGY AND PATHOLOGY GRC/GRS

NANOSCALE SCIENCE AND ENGINEERING FOR AGRICULTURE & FOOD SYSTEMS: ADVANCING FOOD SECURITY, NUTRITION & HEALTH,AGRICULTURAL PRODUCTIVITY & ENVIRONMENT

2021 GORDON RESEARCH CONFERENCE AND SEMINAR ON GEOCHRONOLOGY: EVOLUTION OF THE LITHOSPHERE

THIS PROPOSAL SEEKS FUNDING SUPPORT FOR THE UPCOMING GEOBIOLOGY GORDON RESEARCH SEMINAR (GRS) AND GORDON RESEARCH CONFERENCE (GRC). THE GRC WILL BE CHAIRED BY DR. ALEXANDRA TURCHYN AND CO-CHAIRED BY DR. BOSWELL WING .

2008 GORDON RESEARCH CONFERENCE ON ENVIRONMENTAL SCIENCES: WATER

2022 IMMUNOENGINEERING GORDON RESEARCH CONFERENCE - ABSTRACT: GORDON RESEARCH CONFERENCE FOR IMMUNOENGINEERING, JULY 2022 IMMUNOENGINEERING IS A YOUNG AND VIBRANT FIELD THAT SEEKS TO IMPROVE HUMAN HEALTH VIA CUTTING-EDGE ANALYSIS, MANIPULATION, AND ENGINEERING OF THE IMMUNE SYSTEM. GROUNDED IN DECADES OF WORK IN FUNDAMENTAL IMMUNOLOGY, THE PAST DECADE HAS SEEN A SPIKE IN INTEGRATION OF PRINCIPLES FROM ENGINEERING AND THE PHYSICAL SCIENCES INTO IMMUNOLOGICAL RESEARCH AND ALREADY INCLUDES BREAKTHROUGH IMMUNOTHERAPIES FOR CANCER. HOWEVER, THE IMMUNOENGINEERING COMMUNITY DOES NOT YET HAVE A FLAGSHIP CONFERENCE THAT BRINGS TOGETHER ALL OF ITS DIFFERENT SUB-UNITS. WORKSHOPS HELD AT INDIVIDUAL UNIVERSITIES AND SYMPOSIA WITHIN LARGER CONFERENCES HAVE BEEN WELL ATTENDED, BUT AN INTERNATIONALLY ACCESSIBLE AND DISCUSSION-FOCUSED CONFERENCE THAT SUPPORTS NETWORKING BETWEEN GENERATIONS OF RESEARCHERS AND ACROSS FIELDS HAS BEEN MISSING. SUCH A CONFERENCE IS NEEDED TO BRING TOGETHER LEADERS, NEW INVESTIGATORS, AND TRAINEES FROM DISPARATE FIELDS FOR THE FIRST TIME, TO ADVANCE BOTH TRANSLATIONAL AND FUNDAMENTAL SCIENCE AND TO PROVIDE A FOCAL POINT FOR COLLABORATIVE RELATIONSHIPS, CAREER GUIDANCE, AND MENTORING OF TRAINEES IN THIS FIELD. THEREFORE, THIS PROPOSAL REQUESTS PARTIAL SUPPORT FOR AN INTERNATIONAL MEETING ON IMMUNOENGINEERING AS PART OF THE GORDON RESEARCH CONFERENCE (GRC) SERIES, TO BE HELD IN VENTURA, CA IN JULY 2022. THE SPECIFIC AIMS OF THE CONFERENCE ARE (I) TO INCREASE OUR UNDERSTANDING OF THE FUNDAMENTAL MECHANISMS OF IMMUNOENGINERRING AT THREE LEVELS — BASIC RESEARCH, TRANSLATIONAL STUDIES, AND CLINICAL PRACTICE — BY PROMOTING ENGAGEMENT AND LONG-TERM RELATIONSHIPS ACROSS FIELDS, (II) TO ADVANCE THE CAREERS OF NEW INVESTIGATORS AND TRAINEES IN THE FIELD OF IMMUNOENGINEERING BY SHOWCASING THEIR WORK AND FACILITATING NETWORKING WITH SENIOR INVESTIGATORS AND PEER MENTORS, AND (III) TO ENHANCE DIVERSITY, EQUITY, AND INCLUSION AMONG NEW INVESTIGATORS AND TRAINEES IN IMMUNOENGINEERING VIA STRONG REPRESENTATION AT THE MEETING. THE PROGRAM WILL HAVE A KEYNOTE ADDRESS AND NINE SESSIONS THAT BROADLY ADDRESS GROWTH AREAS OF IMMUNOENGINEERING, MOLECULARLY ENGINEERED IMMUNOTHERAPIES, BIOMATERIALS FOR VACCINES AND IMMUNOMODULATION, SYSTEMS AND COMPUTATIONAL IMMUNOLOGY, IN VITRO MODELS OF IMMUNITY, MICRO-TECHNOLOGIES TO ASSESS IMMUNE CELL FUNCTION, CELLULAR IMMUNOEINEERING, AND TRANSFORMATIVE TOOLS FOR IMMUNOLOGICAL RESEARCH. EACH SESSION WILL FEATURE 1-2 SHORT TALKS SELECTED FROM ABSTRACTS TO HIGHLIGHT WORK BY EARLY STAGE INVESTIGATORS, AS WELL AS POSTER SESSIONS AND AN INNOVATIVE LUNCH-BASED NETWORKING STRATEGY. WE WILL IMPLEMENT STRATEGIES TO INCREASE PARTICIPATION OF WOMAN AND HISTORICALLY UNDERREPRESENTED MINORITIES BY SETTING ASIDE SPECIFIC FUNDING FOR SUCH INDIVIDUALS, TARGETED ADVERTISING, AND ENSURING THAT THEY ARE WELL REPRESENTED IN THE SHORT TALKS. THUS, THE 2022 IMMUNOENGINEERING GRC WILL SET THE STAGE FOR THE ADVANCEMENT OF KNOWLEDGE AND TRANSLATION IN IMMUNOENGINEERING BY PROMOTING ENGAGEMENT AND LONG-TERM RELATIONSHIPS ACROSS FIELDS, WHILE SUPPORTING A DIVERSE BASE OF YOUNG INVESTIGATORS TO ENSURE ITS FUTURE STRENGTH.

2021 MITOCHONDRIA IN HEALTH AND DISEASE GORDON RESEARCH CONFERENCE - PROJECT SUMMARY THIS APPLICATION SEEKS PARTIAL FUNDS TO SUPPORT THE GORDON RESEARCH CONFERENCE (GRC) ON MITOCHONDRIA IN HEALTH AND DISEASE TO BE HELD AUGUST 8-13, 2021. THIS IS THE SECOND IN A NEW SERIES OF GRCS, WHICH EMERGED FROM THE GROWING AWARENESS WITHIN THE MITOCHONDRIAL COMMUNITY OF THE NEED FOR A FORUM TO CAPTURE AND INTEGRATE A WIDE RANGE OF RAPIDLY EVOLVING AREAS OF MITOCHONDRIAL BIOLOGY FROM THE PERSPECTIVE OF BOTH BASIC AND TRANSLATIONAL SCIENCE. THE GRC FORMAT IS PARTICULARLY SUITED FOR THIS FORUM BECAUSE IT PROVIDES A SETTING WHERE CUTTING EDGE UNPUBLISHED FINDINGS ARE PRESENTED IN AN INCLUSIVE ENVIRONMENT THAT ATTRACTS EXPERTS ACROSS LABS WORLDWIDE FOR A FIVE-DAY CONFERENCE. TIME FOR DISCUSSIONS AND NETWORKING ARE RIGOROUSLY PROTECTED AND ENCOURAGED IN EVERY SCIENTIFIC SESSION AND THROUGH FREE TIMES IN THE AFTERNOONS. A SETTING WHERE OPEN DISCUSSION TAKES PLACE ENCOURAGES COLLABORATION AND IS CRUCIAL TO ADVANCING THE FRONTIERS OF MITOCHONDRIAL SCIENCE. IN ADDITION TO ACCELERATING MITOCHONDRIAL RESEARCH AND PROMOTING CROSS-DISCIPLINARY COLLABORATIONS, THE CONFERENCE IS COMMITTED TO ENHANCE VISIBILITY AND PARTICIPATION OF WOMEN SCIENTISTS AND MINORITIES. AS SUCH, 44% OF CONFIRMED SPEAKERS AND 44% OF DISCUSSION LEADERS IN THE CONFERENCE PROGRAM ARE WOMEN. IN ADDITION, SHORT TALKS FROM ABSTRACTS WILL BE PRIORITIZED TO FEATURE RESEARCH BY EARLY CAREER SCIENTISTS, TRAINEES, WOMEN AND MINORITIES. MOREOVER, A GRC-SPONSORED POWER HOUR, WHICH IS AN OPEN COMMUNICATION FORUM, IS SCHEDULED EARLY DURING THE CONFERENCE TO DISCUSS CHALLENGES SURROUNDING DIVERSITY IN SCIENCE. ANOTHER CONFERENCE OBJECTIVE IS TO TRAIN GRADUATE STUDENTS AND POSTDOCS IN MITOCHONDRIAL SCIENCE AND PROVIDE NETWORKING AND INFORMAL MENTORING OPPORTUNITIES TO ENRICH THEIR CAREER DEVELOPMENT. THE FORMAT OF THE 2021 CONFERENCE CONSISTS OF 9 SCIENTIFIC SESSIONS EACH COMPOSED OF 3 FULL TALKS AND ONE SHORT TALK SELECTED FROM ABSTRACTS, AS WELL AS 4 TWO-HOUR POSTER SESSIONS. THE SCIENTIFIC SESSIONS WILL HAVE AN INTEGRATIVE FOCUS ON NOVEL MOLECULAR, CELLULAR AND ORGANISMAL ASPECTS OF MITOCHONDRIAL BIOENERGETICS AND METABOLISM, REDOX REGULATION, GENOME INTEGRITY, PROTEIN BIOGENESIS, AND PROTEOSTASIS, AND MITOCHONDRIA-BASED CROSSTALK MECHANISMS VIA CARRIER SYSTEMS AS WELL AS INTERORGANELLAR COMMUNICATIONS. EACH SESSION HAS A MIXTURE OF TALKS RANGING FROM FUNDAMENTAL BIOLOGIC MECHANISMS TO PHYSIOLOGY/PATHOPHYSIOLOGY. AS SUCH, THE PROGRAM INCLUDES HIGHLY DIVERSE TOPICS WHILE FEATURING FRONTIERS OF KNOWLEDGE GAINED FROM A BROAD RANGE OF APPROACHES, EXPERIMENTAL SYSTEMS AND TISSUE TYPES, AS WELL AS INVESTIGATION OF MULTIPLE DISEASES INVOLVING ALTERATIONS IN MITOCHONDRIAL FUNCTION. THE SCIENTIFIC SESSIONS FEATURE OUTSTANDING MITOCHONDRIAL BIOLOGISTS RANGING FROM ESTABLISHED INVESTIGATORS TO EARLY CAREER SCIENTISTS WHOSE CUTTING-EDGE RESEARCH HAS HAD HIGH IMPACT IN THE FIELDS OF AGING, CANCER, DIABETES AND OBESITY, CARDIOVASCULAR DISEASE, NEURODEGENERATION, AND INBORN ERRORS OF METABOLISM. GIVEN THE COLLECTIVE BREADTH OF EXPERTISE AND RESEARCH INTERESTS WITHIN THE MITOCHONDRIAL COMMUNITY, WE BELIEVE OUR PROGRAM WILL CATALYZE PRODUCTIVE CROSS-DISCIPLINARY INTERACTIONS TO PROPEL THE FIELD FORWARD.

GORDON CONFERENCE ON RENEWABLE ENERGY: SOLAR FUELS

THREE DIMENSIONAL ELECTRON MICROSCOPY GORDON RESEARCH CONFERENCE

2013/2015 GLYCOBIOLOGY GORDON RESEARCH CONFERENCE & GORDON RESEARCH SEMINAR

2011 CHEMICAL OCEANOGRAPHY GORDON RESEARCH CONFERENCE

2020 NEURAL MECHANISMS OF ACOUSTIC COMMUNICATION GORDON RESEARCH CONFERENCE AND SEMINAR

2017 CHEMICAL OCEANOGRAPHY GORDON RESEARCH CONFERENCE: SYNTHESIZING MULTIFACETED DATA IN CHEMICAL OCEANOGRAPHY

2024 AUTOPHAGY IN STRESS, DEVELOPMENT AND DISEASE GORDON RESEARCH CONFERENCE - PROJECT SUMMARY THIS PROPOSAL REQUESTS PARTIAL SUPPORT FOR THE GORDON RESEARCH CONFERENCE (GRC) ON AUTOPHAGY TO BE HELD IN BARGA, ITALY, MARCH 10-14, 2024. AUTOPHAGY IS A FUNDAMENTAL CELLULAR HOMEOSTATIC MECHANISM AFFECTING MANY DEVELOPMENTAL PROCESSES, AS WELL NUMEROUS AGE-RELATED HUMAN DISEASES SUCH AS NEURODEGENERATION AND INFLAMMATION. GROWING EVIDENCE ALSO SUGGESTS AUTOPHAGY AS A MAJOR MOLECULAR MECHANISM OF AGING, WARRANTING ITS MECHANISTIC STUDY. THE BROAD AND LONG-TERM GOAL OF THIS GRC SERIES IS TO HIGHLIGHT THE EXPANDING ROLE AND REGULATION OF AUTOPHAGY IN PHYSIOLOGICAL AND PATHOLOGICAL PROCESSES THAT UNDERLIE HUMAN AGING AND DISEASES. THE SPECIFIC AIMS OF THE 2024 GRC MEETING WILL BE TO CONVENE 40 INVITED SPEAKERS AND DISCUSSION LEADERS IN KEY AREAS OF AUTOPHAGY RESEARCH ALONG WITH 200 PARTICIPANTS FOR A FIVE-DAY CONFERENCE. THE GRC WILL BE PRECEDED BY A GORDON RESEARCH SEMINAR (GRS) DESIGNED TO ENHANCE THE PARTICIPATION OF JUNIOR INVESTIGATORS. THE PROGRAM WILL INCLUDE A KEYNOTE SESSION WITH KEYNOTE ADDRESS FROM THREE WORLD LEADERS WHO HAVE MADE SEMINAL CONNECTIONS BETWEEN MOLECULAR MECHANISMS AND PHYSIOLOGICAL PROCESSES. THE CONFERENCE WILL ALSO FEATURE EIGHT SESSIONS THAT ADDRESS CURRENT ISSUES RELATING TO AGING, NEURODEGENERATION, CANCER, INFLAMMATION, IMMUNITY, BULK AND SELECTIVE AUTOPHAGY MECHANISMS, MEMBRANE DYNAMICS, AND LYSOSOMAL SECRETION AND REPAIR. IN ADDITION, 20 SHORT TALKS WILL BE SELECTED FROM SUBMITTED ABSTRACTS AND GRS PRESENTATIONS, AND TWO POSTER SESSIONS WILL PERMIT ALL PARTICIPANTS TO CONTRIBUTE TO THESE TOPICS. THE SIGNIFICANCE OF THIS APPLICATION IS THAT THE GRC ON AUTOPHAGY HAS BECOME THE MOST IMPORTANT VENUE THAT CRITICALLY INFLUENCES, DIRECTS AND DRIVES RESEARCH IN THE INTERNATIONAL COMMUNITY OF AUTOPHAGY RESEARCHERS. GRC MEETINGS BRING TOGETHER A BROAD GROUP OF INVESTIGATORS WHO ARE AT THE FOREFRONT OF THE AUTOPHAGY RESEARCH AND ALLIED FIELDS, AND PROVIDE AMPLE OPPORTUNITIES FOR JUNIOR SCIENTISTS AND TRAINEES TO PRESENT THEIR WORK AND EXCHANGE IDEAS WITH LEADERS IN THE FIELD, THUS NURTURING THE NEXT GENERATION OF AUTOPHAGY RESEARCH LEADERS, FOLLOWING IN THE FOOTSTEPS OF THE 2016 NOBEL PRIZE WINNER YOSHINORI OHSUMI, WHO DISCOVERED THE MOLECULAR MECHANISMS OF AUTOPHAGY. THE HEALTH RELATEDNESS OF THIS APPLICATION IS THAT AUTOPHAGY DIRECTLY IMPACTS A WIDE SPECTRUM OF HUMAN HEALTH AND DISEASES RELATED TO AGING, SUCH CHRONIC INFLAMMATION AND NEURODEGENERATION. THE RESEARCH HIGHLIGHTED BY GRC MEETINGS ON AUTOPHAGY WILL LEAD TO A GREATER MOLECULAR UNDERSTANDING OF A CRITICAL PROCESS AND HELP DEVELOP NEW APPROACHES TO TREAT AGE-RELATED DISEASES AND IMPROVE HEALTHSPAN.

CONFERENCE: 2025 APPLIED AND ENVIRONMENTAL MICROBIOLOGY GRC -MICROORGANISMS ARE PRESENT VIRTUALLY EVERYWHERE ON EARTH. MICROBES CARRY OUT PROCESSES THAT MAKE EARTH HABITABLE AND HELP TO MAINTAIN PLANT, HUMAN, AND ANIMAL HEALTH. IN OTHER WORDS, AN UNDERSTANDING OF MICROORGANISMS AND THEIR ACTIVITIES IS CRITICAL TO SUSTAIN CLEAN AIR AND WATER, TO MAINTAIN FOOD SECURITY AND TO PREVENT HUMAN DISEASE. THIS GRANT WILL SUPPORT THE PARTICIPATION OF EARLY-CAREER SCIENTISTS IN THE GORDON CONFERENCE ON APPLIED AND ENVIRONMENTAL MICROBIOLOGY (GRC-AEM)AT MOUNT HOLYOKE COLLEGE, JULY 13-18, 2025. ESTABLISHED IN 1950, THE GRC-AEM BRINGS TOGETHER SCIENTISTS TO ADDRESS RESEARCH ON THE IMPORTANCE OF MICROBES IN HUMAN HEALTH, INTERACTIONS OF MICROBES WITH ANIMALS AND PLANTS, TERRESTRIAL AND AQUATIC BIOGEOCHEMICAL CYCLES, BIOREMEDIATION OF CONTAMINATED LAND AND WATER, PRODUCTION OF BIOFUELS, AND USE OF MICROBES AS BIOCATALYSTS IN INDUSTRY. AREAS OF MICROBIOLOGICAL RESEARCH COVERED BY THE GRC-AEM HAVE AN IMMENSE SOCIETAL IMPACT ON THE ENVIRONMENT AND MANKIND AND THUS THIS GRC REMAINS HIGHLY TOPICAL AND A VERY VIBRANT RESEARCH FIELD. THE MAIN GOALS OF THE GRC-AEM ARE TO PROVIDE AN OPEN FORUM FOR THE PRESENTATION AND DISCUSSION OF THE LATEST RESEARCH FINDINGS ON ENVIRONMENTAL AND APPLIED APPLICATIONS OF MICROORGANISMS FROM THE SINGLE CELL TO THE ECOSYSTEM LEVEL. THE GRC AEM WILL ADDRESS CRITICAL OR EVEN CONTROVERSIAL ISSUES FOR THE DEVELOPMENT OF NEW TECHNOLOGIES. THE 2025 CONFERENCE SUBTITLED BRIDGING SCALES TO UNVEIL THE POWER OF ENVIRONMENTAL MICROBIOLOGY. THE CONFERENCE HAS A STRONG TRACK RECORD OF STIMULATING CUTTING EDGE AND INNOVATIVE RESEARCH BY SCIENTISTS IN ACADEMIA, RESEARCH INSTITUTES/FOUNDATIONS AND GOVERNMENT AND INDUSTRIAL LABORATORIES. THERE WILL BE A GORDON RESEARCH SEMINAR (GRS-AEM) ASSOCIATED WITH THE GRC-AEM FOCUSSED ON EXPLORING COMPLEX NETWORKS OF MICROBIAL COMMUNITIES, WHICH WILL BE EXCLUSIVELY FOR PHD STUDENTS AND POSTDOCTORAL RESEARCHERS. THE GRC-AEM PROGRAM WILL ALSO HAVE SEVERAL POSTER TALKS BY EARLY-CAREER RESEARCHERS CHOSEN FROM POSTER ABSTRACT SUBMISSIONS. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

MOLECULAR & CELLULAR NEUROBIOLOGY 2008 GORDON RESEARCH CONFERENCE

2018 CARDIAC REGULATORY MECHANISMS GORDON RESEARCH CONFERENCE AND GORDON RESEARCH SEMINAR

2015 STRESS PROTEINS IN GROWTH, DEVELOPMENT AND DISEASE GRC