Aim Inc

CLASS 8 TRUCK FRIGHT EFFICIENCY IMPROVEMENT PROJECT

TO PROVIDE EMERGENCY AGRICULTURE, NUTRITION, WATER, SANITATION AND HYGIENE, ECONOMIC RECOVERY AND MARKET SYSTEMS, HEALTH, AND FOOD ASSISTANCE ACTIVITIES IN DRC

NEW AWARD TO PROVIDE FOOD ASSISTANCE AND SERVICES IN THE HEALTH, NUTRITION, AND WASH SECTORS TO AFFECTED POPULATIONS IN BORNO AND YOBE STATES.

TO PROVIDE VITAL MULTI-SECTORAL SUPPORT ACTIVITES FOR INTERNALLY DISPLACED PEOPLE (IDPS) IN THE DEMOCRATIC REPUBLIC OF THE CONGO (DRC).

EMERGENCY FOOD PROGRAM IN NIGERIA

NEW AWARD NUMBER: DE-EE0009860 TITLE: DAIMLER TRUCKS NORTH AMERICA SUPERTRUCK 3 PROJECT: ULTRA-EFFICIENT LONG-HAUL HYDROGEN FUEL CELL TRACTOR AWARD RECIPIENT: DAIMLER TRUCKS NORTH AMERICA LLC

IMPROVING TRANSPORTATION EFFICIENCY THROUGH INTEGRATED VEHICLE, ENGINE, AND POWERTRAIN RESEAERC - SUPERTRUCK II

HEALTH CENTER CLUSTER

HEALTH CENTER CLUSTER

24-MONTH AWARD TO SUPPORT MULTI-SECTORAL RESPONSE IN NIGERIA

OVC FY 10 VOCA VICTIM COMPENSATION FORMULA

AWARDING AGENCY: U.S. AGENCY FOR INTERNATIONAL DEVELOPMENT CFDA LISTING / ASSISTANCE LISTING: 98.001 – USAID FOREIGN ASSISTANCE FOR PROGRAMS OVERSEAS CFDA NARRATIVE EXCERPT: THE PURPOSE OF USAID’S BUREAU FOR HUMANITARIAN ASSISTANCE (BHA) IS TO PROVIDE LIFE-SAVING HUMANITARIAN ASSISTANCE—INCLUDING FOOD, WATER, SHELTER, EMERGENCY HEALTHCARE, AND OTHER CRITICAL AID— TO THE WORLD’S MOST VULNERABLE AND HARDEST-TO-REACH POPULATION AFFECTED BY NATURAL, MAN-MADE AND COMPLEX DISASTER. BHA IS THE LEAD FEDERAL COORDINATOR FOR INTERNATIONAL DISASTER ASSISTANCE, HARNESSING THE EXPERTISE AND UNIQUE CAPACITIES OF OTHER U.S. GOVERNMENT, NON-U.S. ENTITIES & PUBLIC INTERNATIONAL ORGANIZATIONS TO EFFECTIVELY RESPOND TO NATURAL DISASTERS, COMPLEX CRISES AND FOOD INSECURITY AROUND THE WORLD. RECIPIENT: ACTION CONTRE LA FAIM (ACF) THIS AWARD WILL PROVIDE FINANCIAL SUPPORT TO ACTION CONTRE LA FAIM FOR A PROGRAM ENTITLED, “MULTISECTOR EMERGENCY RESPONSE AND CRISIS RESILIENCE TO THE CONFLICT-AFFECTED POPULATIONS IN CABO DELGADO” IN MOZAMBIQUE. THE GOAL IS TO RESPOND TO THE CONFLICT-AFFECTED POPULATIONS NEEDS IN THE CABO DELGADO PROVINCE THROUGH LIVE-SAVING AND SUSTAINING INTERVENTIONS TO BUILD COMMUNITIES RESILIENCE. THE TOTAL NUMBER OF BENEFICIARIES THAT WILL BE SUPPORTED UNDER THIS AWARD IS 36,283 INDIVIDUALS.

HEALTH CARE INNOVATION CHALLENGE: A PROGRAM TO ADVANCE THE TRIPLE AIM FOR SERIOUSLY MENTALLY ILL POPULATIONS

TO PROVIDE EMERGENCY MULTI-SECTORAL SERVICES TO CONFLICT-AFFECTED POPULATIONS IN NORTHEAST NIGERIA.

TO PROVIDE MULTI-SECTOR SUPPORT TO CONFLICT-AFFECTED POPULATIONS IN BURKINA FASO.

NEW EMERGENCY AWARD TO ACF IN MADAGASCAR.

DOE HEAVY TRUCK ENGINE PROGRAM

OVC FY 09 VOCA VICTIM COMPENSATION FORMULA GRANT PROGRAM

TO APPROVE A NEW EMERGENCY AWARD IN THE KASAIS DRC AND OBLIGATE $11,348,259 IN FY20 IDA/OCO FUNDS

AIMS COMMUNITY COLLEGE CARES ACT HIGHER EDUCATION EMERGENCY RELIEF FUND INSTITUTIONAL FUNDS

FOR A NEW AWARD IN HEALTH, ECONOMIC RECOVERY AND MARKET SYSTEMS, FOOD ASSISTANCE, NUTRITION, AND WATER, SANITATION, AND HYGIENE.

FY08 VOCA COMPENSATION GRANT PROGRAM

TO PROVIDE FOOD AND AGRICULTURE ASSISTANCE IN DRC

OVC FY 11 VOCA VICTIM COMPENSATION FORMULA

BELT: BLACKS & EXACERBATIONS ON LABA VS. TIOTROPIUM

TO PROVIDE EMERGENCY HEALTH, NUTRITION, AND WATER, SANITATION, AND HYGIENE SERVICES TO CONFLICT-AFFECTED POPULATIONS IN NORTHEAST NIGERIA

THIS PROJECT WILL SUPPORT VOCA VICTIM COMPENSATION PROGRAMS ACROSS THE NATION THAT PROVIDE CRUCIAL FINANCIAL ASSISTANCE TO HUNDREDS OF THOUSANDS OF CRIME VICTIMS EACH YEAR.

TO PROVIDE FOOD, AGRICULTURE, AND NUTRITION EMERGENCY ASSISTANCE TO MARGINALIZED PEOPLE IN DRC

PURCHASE LAND AND PROVIDE TECHNICAL ASSISTANCE TO FARMERS TO INCREASE CAPITAL AND MARKET ACCESS.

CARES ACT HIGHER EDUCATION EMERGENCY RELIEF FUND

HYDROGEN TO THE HIGHWAYS

THE GRANT AWARD PROVIDES FUNDS FROM THE CRIME VICTIMS FUND TO ENHANCE STATE VICTIM COMPENSATION PAYMENTS TO ELIGIBLE CRIME VICTIMS. VICTIMS OF CRIME ACT (VOCA) COMPENSATION FUNDS PROVIDE FINANCIAL ASSISTANCE TO FEDERAL AND STATE VICTIMS OF CRIME. NC/NCF

THIS AWARD WILL SUPPORT THE RECONCILIATION AND PROSPERITY IN IRAQ THROUGH AMERICAN-STYLE HIGHER EDUCATION PROJECT.

HEALTH AND NUTRITION SUPPORT FOR BURKINA FASO.

OVC FY 12 VOCA VICTIM COMPENSATION FORMULA

EMERGENCY RESPONSE TO FOOD INSECURITY OF POPULATION AFFECTED BY THE CRISIS IN THE KASAI REGIONS

THE PURPOSE OF THIS AWARD IS TO PROVIDE ACTION CONTRE LA FAIM (ACF) FUNDING IN THE AMOUNT OF $3 015 031 OVER A PERIOD OF TWELVE MONTHS FROM JULY 1

NEW AWARD (GRANT) TO PROVIDE FINANCIAL SUPPORT TO ACTION CONTRE LA FAIM FOR A PROGRAM ENTITLED, “MULTI SECTORAL EMERGENCY RESPONSE TO THE 2020/21 SEVERE DROUGHT CRISIS IN SOUTHERN MADAGASCAR” IN MADAGASCAR.

BANGLADESH FOOD SECURITY PROGRAM

ACF 1 YEAR AWARD FOR FOOD ASSISTANCE, HEALTH, NUTRITION AND WASH SUPPORT TO VULNERABLE POPULATIONS IN CAR.

SECURING THE PEACE IN IRAQ BY EDUCATING A NEW GENERATION OF LEADERS

CHAD EMERGENCY RESPONSE AND EARLY RECOVERY ACTIVITIES FOR KANEM PROVINCE

TO IMPROVE SUPPLY AND PROVIDE ACCESS TO A BUFFER STOCK OF READY TO USE THERAPEUTIC FOOD TO HUMANITARIAN PARTNERS IN NORTHEAST NIGERIA

DE-EE0008804 DAIMLER TRUCKS NORTH AMERICA LLC ''DEVELOPMENT AND COMMERCIALIZATION OF HEAVY-DUTY BATTERY-ELECTRIC TRUCKS UNDER DIVERSE CLIMATE CONDITIONS''

OVC FY15 VOCA VICTIM COMPENSATION FORMULA

EMERGENCY FOOD SECURITY PROGRAM IN DRC

EMERGENCY FOOD SECURITY AND LIVELIHOOD SUPPORT FOR AFFECTED POPULATION IN DJUGU TERRITORY, ITURI PROVINCE DRC

FY24 IDA EMERGENCY ASSISTANCE AND RAPID RESPONSE TO IMPROVE ACCESS TO HEALTH, NUTRITION, PROTECTION AND WASH SERVICES IN THE FAR NORTH REGION OF CAMEROON

EMERGENCY FOOD SECURITY PROGRAM IN HAITI

EFSP PROGRAM IN HAITI

THIS PROJECT WILL PROVIDE SUPPORT TO AMERICAN-STYLE HIGHER EDUCATION IN IRAQ.

EMERGENCY FOOD SECURITY PROGRAM - DRC

NEW 15-MONTH AWARD IN IDA FUNDS TO SUPPORT NUTRITION ACTIVITIES IN BORNO, ADAMAWA, & YOBE STATES OF NORTHEAST NIGERIA.

THE GRANT AWARD PROVIDES FUNDS FROM THE CRIME VICTIMS FUND TO ENHANCE STATE VICTIM COMPENSATION PAYMENTS TO ELIGIBLE CRIME VICTIMS. VICTIMS OF CRIME ACT (VOCA) COMPENSATION FUNDS PROVIDE FINANCIAL ASSISTANCE TO FEDERAL AND STATE VICTIMS OF CRIME. NC/NCF

SUSTAINABLE CONDOM SOLUTIONS PROJECT (SCSP)

DEVELOPMENT OF A NOVEL ORAL ANTIBIOTIC FOR THE TREATMENT OF DRUG RESISTANT GONORRHEA - PROJECT SUMMARY / ABSTRACT THE CDC HAS IDENTIFIED NEISSERIA GONORRHOEAE AS A PATHOGEN OF THE HIGHEST THREAT LEVEL (“URGENT THREAT”) TO THE US PUBLIC HEALTH. CURRENTLY THERE IS ONLY A SINGLE RECOMMENDED AGENT REMAINING ON THE CDC TREATMENT GUIDELINES, AN INTRAMUSCULAR INJECTION OF THE EXTENDED SPECTRUM CEPHALOSPORIN, CEFTRIAXONE. HOWEVER, IN THE PAST DECADE, REPORTS OF RESISTANCE TO CEFTRIAXONE HAVE APPEARED ACROSS THE GLOBE. IF ONE OF THESE STRAINS WERE TO DISSEMINATE WIDELY, WE WOULD BE FACING AN ERA OF UNTREATABLE GONORRHEA. UNTREATED INFECTIONS CAN CAUSE SERIOUS AND LIFE-THREATENING SEQUELAE. THUS, DEVELOPING NEW ANTIBIOTICS WITHOUT CROSS-RESISTANCE TO THE CURRENT THERAPEUTICS IS OF CRITICAL IMPORTANCE TO PUBLIC HEALTH. BETWEEN 20 AND 40% OF INDIVIDUALS INFECTED WITH N. GONORRHOEAE ARE CO-INFECTED WITH CHLAMYDIA TRACHOMATIS, A PREDOMINANTLY ASYMPTOMATIC INFECTION THAT CAN HAVE DEVASTATING LONG-TERM EFFECTS ON REPRODUCTIVE HEALTH AND FERTILITY IF NOT TREATED. CEFTRIAXONE IS NOT ACTIVE AGAINST C. TRACHOMATIS AND THE CLINICAL SIGNS AND SYMPTOMS OF GONORRHEA AND CHLAMYDIA ARE INDISTINGUISHABLE FROM ONE ANOTHER. THEREFORE, UNLESS CHLAMYDIA CAN BE EXCLUDED BY A LABORATORY DIAGNOSIS, EMPIRIC TREATMENT FOR GONORRHEA TYPICALLY INVOLVES ADMINISTRATION OF TWO DIFFERENT CLASSES OF ANTIBIOTICS IN ORDER TO COVER BOTH PATHOGENS. A SINGLE ORAL ANTIBIOTIC EFFECTIVE AGAINST BOTH INFECTIONS WOULD CHANGE THE CURRENT TREATMENT PARADIGM, IMPROVING ADHERENCE TO TREATMENT AS WELL AS REDUCING THE IMPACT THAT DUAL ANTIBIOTIC THERAPY CAN HAVE ON PROMOTING RESISTANCE IN CO-INFECTING PATHOGENS AND COMMENSAL ORGANISMS. FURTHERMORE, AS AN ORAL ANTIBIOTIC, IT WOULD PROVIDE A MUCH-NEEDED TREATMENT OPTION TO PATIENTS AND PHYSICIANS AND ALLOW FOR EXPEDITED PARTNER THERAPY. AIMMAX THERAPEUTICS HAS DISCOVERED A NOVEL ANTIBIOTIC WITH ACTIVITY AGAINST N. GONORRHOEAE THAT IS COMPARABLE TO CEFTRIAXONE. IT HAS DEMONSTRATED POTENT ACTIVITY AGAINST MULTIDRUG- AND PAN-RESISTANT N. GONORRHOEAE ISOLATES, INCLUDING ISOLATES RESISTANT TO CEFTRIAXONE, WITH NO EVIDENCE OF CROSS-RESISTANCE TO EXISTING CLASSES. THE OVERALL GOAL OF THIS PROPOSED FASTTRACK SBIR APPLICATION IS TO DEVELOP A NOVEL ORAL ANTIBIOTIC FOR THE TREATMENT OF GONORRHEA AS THE TOP PRIORITY, AND IF SUITABLE, FOR THE TREATMENT OF CHLAMYDIA ALSO, THE TWO MOST COMMON BACTERIAL SEXUALLY TRANSMITTED INFECTIONS IN THE US. THE STUDIES PROPOSED HEREIN WILL CONFIRM THE SUITABILITY OF THIS NEW CLASS OF ANTIBIOTIC FOR THE TREATMENT OF GONORRHEA AND CHLAMYDIA, IDENTIFY A FORMULATION THAT DELIVERS OPTIMAL ORAL BIOAVAILABILITY AND PLASMA EXPOSURE TO PROVIDE EFFECTIVE TREATMENT, AND ADVANCE DEVELOPMENT TOWARDS FILING OF AN IND. RISING ANTIBIOTIC RESISTANCE COMBINED WITH EASE OF TRANSMISSION, RISKS FOR OUTBREAKS, AND LACK OF SECOND-LINE TREATMENT OPTIONS, ALL POINT TO THE CRITICAL NEED TO IDENTIFY NEW ANTIBIOTICS FOR THE TREATMENT OF GONORRHEA AND EXPEDITIOUSLY ADVANCE THEIR DEVELOPMENT TO THE CLINIC.

OVC FY16 VOCA VICTIM COMPENSATION FORMULA

OVC FY 20 VOCA VICTIM COMPENSATION FORMULA

HIGHER EDUCATION EMERGENCY RELIEF FUND ASSISTING STUDENTS AND INSTITUTIONS AFFECTED BY COVID-19.

TO APPROVE A NEW AWARD TO ACF FOR HEALTH, NUTRITION, FOOD ASSISTANCE, AND COORDINATION IN MADAGASCAR AND OBLIGATE $3.1 MILLION IN FY24 IDA. THE OBJECTIVE OF THIS PROGRAM IS TO CONTRIBUTE TO THE FOOD AND NUTRITION SECURITY OF THE MOST VULNERABLE POPULATIONS – ESPECIALLY CHILDREN UNDER FIVE – AFFECTED BY THE DROUGHT THROUGH INCREASED ACCESS TO FOOD AND NUTRITION AND HEALTH SERVICES.

AWARDING AGENCY: U.S. AGENCY FOR INTERNATIONAL DEVELOPMENT CFDA LISTING / ASSISTANCE LISTING: 98.001 – USAID FOREIGN ASSISTANCE FOR PROGRAMS OVERSEAS CFDA NARRATIVE EXCERPT: THE PURPOSE OF USAID’S BUREAU FOR HUMANITARIAN ASSISTANCE (BHA) IS TO PROVIDE LIFE-SAVING HUMANITARIAN ASSISTANCE—INCLUDING FOOD, WATER, SHELTER, EMERGENCY HEALTHCARE, AND OTHER CRITICAL AID— TO THE WORLD’S MOST VULNERABLE AND HARDEST-TO-REACH POPULATION AFFECTED BY NATURAL, MAN-MADE AND COMPLEX DISASTER. BHA IS THE LEAD FEDERAL COORDINATOR FOR INTERNATIONAL DISASTER ASSISTANCE, HARNESSING THE EXPERTISE AND UNIQUE CAPACITIES OF OTHER U.S. GOVERNMENT, NON-U.S. ENTITIES & PUBLIC INTERNATIONAL ORGANIZATIONS TO EFFECTIVELY RESPOND TO NATURAL DISASTERS, COMPLEX CRISES AND FOOD INSECURITY AROUND THE WORLD. BHA TAKES A HOLISTIC LOOK AT HUMANITARIAN AID, PROVIDING ASSISTANCE BEFORE, DURING AND AFTER A CRISIS—FROM READINESS AND RESPONSE TO RELIEF AND RECOVERY. THIS INCLUDES NON-EMERGENCY PROGRAMMING THAT IS FOUNDATIONAL TO LINKING HUMANITARIAN ASSISTANCE TO LONG-TERM DEVELOPMENT AND THE JOURNEY TO SELF-RELIANCE. RECIPIENT – ACTION CONTRE LA FAIME (ACF) THIS AWARD WILL PROVIDE FINANCIAL SUPPORT TO ACTION CONTRE LA FAIM FOR A PROGRAM ENTITLED, “STABILIZING CRISIS-AFFECTED AND VULNERABLE HOUSEHOLDS IN MWENEZI AND CHIREDZI DISTRICTS, ZIMBABWE, THROUGH STRENGTHENED LIVELIHOODS” IN ZIMBABWE. THE GOAL IS TO STRENGTHEN RESILIENT LIVELIHOODS AND SELF-RELIANCE OF HOUSEHOLDS VULNERABLE TO THE MULTIFACETED CRISIS IN ZIMBABWE THROUGH IMPROVED HOUSEHOLD PRODUCTION, ACCESS TO DIVERSIFIED INCOME SOURCES, SANITATION AND WATER SERVICES, AND ANTICIPATORY ACTIONS TO POTENTIAL CRISES IN RURAL AREAS OF MWENEZI AND CHIREDZI DISTRICTS. THE TOTAL NUMBER OF BENEFICIARIES THAT WILL BE SUPPORTED UNDER THIS AWARD IS 32,895 INDIVIDUALS.

RECOVERY ACT - OVC FY09 VOCA VICTIM COMPENSATION FORMULA GRANT PROGRAM

ENHANCING SELF-RELIANCE OF VULNERABLE REFUGEES AND HOST COMMUNITIES THROUGH INTEGRATED LIVELIHOODS AND MENTAL HEALTH AND PSYCHOSOCIAL SUPPORT IN JORDAN

NEW $3M IDA (FD-X23) FUNDED (ER4) 15-MONTH AWARD TO ACF ZIMBABWE, SUPPORTING AGRICULTURE, ERMS, AND WASH SERVICES IN GOKWE NORTH AND KARIBA DISTRICTS.

DESCRIPTION:THIS AGREEMENT PROVIDES FUNDING TO THE CITY OF EPHRAIM TO IMPLEMENT ITS PROJECT TO INCREASE RESILIENCY OF THEIR WATER SYSTEM AS DIRECTED IN THE 2022 CONSOLIDATED APPROPRIATIONS ACT OR AS IDENTIFIED IN AN APPROVED TECHNICAL CORRECTION IF ONE HAS BEEN APPROVED FOR THIS PROJECT. ACTIVITIES:THE ACTIVITIES TO BE PERFORMED INCLUDE THE EXECUTION AND IMPLEMENTATION OF A DRINKING WATER INFRASTRUCTURE CONSTRUCTION PROJECT. WORKPLAN ACTIVITIES CONSIST OF CONSTRUCTION OF A REPLACEMENT WATERLINE UP EPHRAIM'S CANYON AND TO CONNECT TO RELEVANT WATER TANKS. SUBRECIPIENT:NO SUBAWARDS ARE INCLUDED IN THIS ASSISTANCE AGREEMENT.OUTCOMES:THE ANTICIPATED DELIVERABLES INCLUDE REPLACED AGING WATERLINES. THE EXPECTED OUTCOMES INCLUDE LESS WATERLINE BREAKAGE. THE INTENDED BENEFICIARIES INCLUDE RESIDENTS OF EPHRAIM

NEW AWARD TO SUPPORT ECONOMIC RECOVERY AND MARKET SYSTEMS; RISK MANAGEMENT POLICY AND PRACTICE; AND WATER, SANITATION, AND HYGIENE IN DISASTER-AFFECTED COMMUNITIES.

ACF HAITI 202E

IMPROVING THE LIVING CONDITIONS AND WELLBEING OF THE POPULATIONS IMPACYED BY THE MOSUL CRISIS THROUGH AN INTEGRATED LIVELIHOODS, WASH AND PROTECTION ACTION.

HIGHER EDUCATION EMERGENCY RELIEF FUND ASSISTING STUDENTS AND INSTITUTIONS AFFECTED BY COVID-19.

COMMUNITY SYSTEM STRENGTHENING FOR REDUCING VULNERABILITY, RESTORING ECONOMIC SUSTAINABILITY, AND IMPROVING RECOVERY FROM COVID-19 IN ZIMBABWE

STRENGTHENING AMERICAN-STYLE HIGHER EDUCATION IN IRAQ - CAREER PLANNING FOR IRAQ`S RE-ENGAGING STUDENTS WITH CAMPUS-BASED LEARNING PROJECT.

OVC FY13 VOCA VICTIM COMPENSATION FORMULA

THIS AWARD SUPPORTS THE SECURING THE PEACE IN IRAQ THROUGH SUPPORT TO AMERICAN-STYLE HIGHER EDUCATION PROJECT.

INNOVATIVE HUMANITARIAN LOGISTICS COOPERATION, “INNOV LOG”

IMPROVE EXISTING AIRPORT

HUMANITARIAN ASSISTANCE SUPPORT THROUGH ERMS, WASH, AND PROTECTION.

OPERATIONAL AND SURGE SUPPORT FOR CRISIS-AFFECTED NATIONAL COORDINATION PLATFORMS (NCP) THROUGH THE GLOBAL WASH CLUSTER (GWC) FIELD SUPPORT TEAM (FST)

PREPARE FOR, MITIGATE, AND ADDRESS THE IMPACT OF COVID-19 ON THE SOCIO-ECONOMIC STATUS AND MENTAL WELLBEING OF VULNERABLE REFUGEES AND HOST COMMUNITY MEMBERS IN JORDAN.

SYNTHOPLATE: INTRAVENOUS HEMOSTATIC NANOTECHNOLOGY TO MITIGATE BLEEDING IN THROMBOCYTOPENIA - PROJECT SUMMARY/ABSTRACT THE NORMAL PLATELET COUNT IN HUMAN BLOOD IS 150,000-400,000/ΜL, AND THESE PLATELETS ARE RESPONSIBLE FOR EFFICIENT HEMOSTATIC SURVEILLANCE AND BLEEDING MITIGATION IN THE BODY. THROMBOCYTOPENIA (TCP, LOW PLATELET COUNT) IS A CONDITION CAUSED BY A DECREASE IN PLATELET PRODUCTION, INCREASE IN PLATELET DESTRUCTION OR CONSUMPTION, OR INCREASE IN SPLENIC SEQUESTRATION. THE AGE-ADJUSTED PREVALENCE OF IMMUNE THROMBOCYTOPENIC PURPURA (ITP) IS ESTIMATED TO BE 3.3 PER 100,000 PERSONS IN THE USA, WHILE DRUG-INDUCED TCP AFFECTS 1-2 PER 100,000 PERSONS. THE MAJORITY (>95%) OF TCP CASES RESULT FROM AUTOIMMUNE DISORDERS OR ARE INDUCED BY CHEMO- AND RADIOTHERAPIES AS WELL AS OTHER PHARMACEUTICALS. AT PLATELET COUNTS <50,000/ΜL, SURGICAL PROCEDURES ARE COMPLICATED BY HIGH BLEEDING RISKS AND ANY MINOR INJURY MAY LEAD TO EXCESSIVE BLEEDING. AT COUNTS <10,000/ΜL, SPONTANEOUS BLEEDING BECOMES A MAJOR CONCERN. THEREFORE, FREQUENT THERAPEUTIC AND PROPHYLACTIC PLATELET TRANSFUSIONS ARE REQUIRED TO INCREASE PLATELET COUNTS AND MITIGATE BLEEDING RISKS. HOWEVER, THE AVAILABILITY OF NATURAL PLATELET PRODUCTS IS SEVERELY LIMITED BY A NEAR-STATIC POOL OF DONORS AND A VERY SHORT SHELF-LIFE (3-5 DAYS) DUE TO HIGH RISKS OF BACTERIAL CONTAMINATION AND STORAGE-RELATED PLATELET ACTIVATION AND DEGRANULATION. THEREFORE, THERE EXISTS A SIGNIFICANT UNMET CLINICAL NEED FOR A THERAPEUTIC AGENT THAT CAN MITIGATE BLEEDING COMPLICATIONS INTRAVENOUSLY IN TCP PATIENTS, WHILE ALLOWING REDUCED CONTAMINATION AND LONG SHELF-LIFE WITHOUT COMPROMISING FUNCTION. TO THIS END, WE HAVE DEVELOPED A SYNTHETIC HEMOSTATIC NANOTECHNOLOGY, CALLED SYNTHOPLATETM, THAT MIMICS PLATELET’S ABILITY TO ADHERE AND AGGREGATE SPECIFICALLY AT A SITE OF INJURY IN THE BODY. IN PHASE I OF THIS SBIR, WE DEMONSTRATED PLATELET-MIMETIC HEMOSTATIC FUNCTIONS IN VITRO AS WELL AS IN VIVO IN PROOF-OF-CONCEPT TCP MURINE MODELS OF BLEEDING. BUILDING ON THIS IN THE PROPOSED PHASE II STUDIES, WE AIM TO: 1) ESTABLISH APPROPRIATE CLINICAL BIOMARKERS FOR MONITORING SP EFFICACY IN THROMBOCYTOPENIC (TCP) PATIENT BLOOD SAMPLES, 2) DETERMINE THE EFFECTIVE PHARMACODYNAMIC (PD) DOSING WINDOW OF SYNTHOPLATETM IN A RABBIT BLEEDING MODEL OF THROMBOCYTOPENIA, AND 3) ESTABLISH THE PHARMACOKINETIC (PK) PROFILE OF SP IN HEALTHY AND THROMBOCYTOPENIC (TCP) RABBITS. ALTOGETHER, THESE EXPERIMENTS WILL ESTABLISH AND CORRELATE PK WITH EX VIVO FUNCTIONAL ASSAYS AND IN VIVO PD TO GUIDE CLINICAL EVALUATION. SUCCESS IN THIS PHASE II PROPOSAL WILL BE USED TO GENERATE A TARGET PRODUCT PROFILE (TPP), WHICH WILL GUIDE CLINICAL PROTOCOL DESIGN, AS WELL AS AID IN RAISING FOLLOW-ON-FUNDING AND PARTNERSHIPS FOR PRODUCT DEVELOPMENT FROM MULTIPLE POTENTIAL SOURCES. BUILDING ON THESE RESULTS, PHASE III WILL IMPLEMENT DEFINED DOSAGE GUIDELINES FOR IND-ENABLING PHARM/TOX STUDIES WITH GMP-MANUFACTURED SP AND THEREBY PROGRESS TOWARDS SUBMITTING AN IND APPLICATION FOR CLINICAL EVALUATION.

THIS AWARD WILL SUPPORT THE INCREASING SOCIAL INCLUSION TO IMPROVE ACCESS AND EXCELLENCE IN IRAQI HIGHER EDUCATION PROJECT.

HIGHER ORDER STRUCTURE ANALYSIS OF PROTEIN THERAPEUTICS BY COVALENT LABELING MS

CONGRESSIONALLY DIRECTED SPENDING FOR CONSTRUCTION PROJECTS

COMMUNITY PROJECT FUNDING/CONGRESSIONALLY DIRECTED SPENDING - CONSTRUCTION - IT TAKES PHILLY/THE BLACK DOCTORS COVID19 CONSORTIUM (BDCC) REQUESTS $2,000,000 IN FUNDING FROM U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES CONGRESSIONALLY DIRECTED SPENDING (CDS): CONSTRUCTION PROJECTS TO SUPPORT THE CONSTRUCTION OF A NEW PEDIATRIC HEALTH CENTER, ALA STANFORD HEALTH EQUITY PEDIATRICS CENTER, TO BE BUILT AT THE FORMER SITE OF THE HISTORIC CARMAN GARDENS SKATING RINK. THIS PROJECT WOULD BE PHYSICALLY LOCATED AT 3225 GERMANTOWN AVE, PHILADELPHIA, PA 19140. THE COST FOR THE TOTAL PROJECT IS $4,819,846. THE EXISTING MASONRY STRUCTURE IS 10,000 SQUARE FEET. THE FINISHED PROJECT WILL FEATURE CLINAL AREAS ROOMS FOR PHLEBOTOMY AND RADIOLOGY. BDCC WILL LEASE THE PROPERTY THAT IS OWNED BY GERMANTOWN LIBERTY ACQUISITIONS, LLC. THE OWNERS AGREES THAT BDCC WILL MAKE CERTAIN IMPROVEMENTS TO THE PROPERTY TO BE DESCRIBE WITHIN THIS APPLICATION TO HRSA CDS. CONSTRUCTION FOR THE NEWLY RENOVATED ALA STANFORD HEATH EQUITY PEDIATRIC CENTER WILL ALLOW US TO PROVIDE HIGH QUALITY, CULTURALLY COMPETENT AND COMPASSIONATE HEALTHCARE SERVICES TO THE SURROUNDING NORTH PHILADELPHIA NEIGHBORHOODS IN AN EFFORT TO ADDRESS HEALTH DISPARITIES AND TO DECREASE MORBIDITY AND MORTALITY RATES AMONG AFRICAN-AMERICANS AND OTHER PERSONS OF COLOR AND THE BROADER COMMUNITY UNDER THE CLINICAL GUIDANCE OF TOP TIER MEDICAL PROFESSIONALS OF COLOR. CDS FUNDING WILL BE UTILIZED TO SUPPORT CONSTRUCTION AND RENOVATIONS ACTIVITY THAT WILL PRODUCE THE MEDICAL FACILITY, INCLUDING THE MATERIALS THAT NEED TO BE ACCOUNTED FOR DURING CONSTRUCTION. THE CONSTRUCTION ACTIVITIES AND PURCHASES INCLUDE: DEMOLITION, CONCRETE, METALS, WOODS, PLASTICS, COMPOSITES, THERMAL AND MOISTURE PROTECTIONS, CREATING OPENINGS AND FINISHES, KITCHEN EQUIPMENT, MEDICAL EQUIPMENT, FURNISHINGS, FIRE SUPPRESSION, PLUMBING, HVAC, ELECTRICAL, COMMUNICATIONS, ELECTRIC SAFETY, AND SECURITY. THE ESTIMATED PROJECT COMPLETION DATE IS JULY 2023. IN JUNE 2022, BDCC WILL SIGN A LEASE AGREEMENT, WHICH THEY ARE CURRE NTLY NEGOTIATING, WITH GERMANTOWN LIBERTY ACQUISITIONS, LLC TENANT FOR A PERIOD OF 15 YEARS FROM THE SUBSTANTIAL COMPLETION OF CERTAIN IMPROVEMENTS TO THE EXISTING BUILDING. - THE ANTICIPATED CONSTRUCTION DRAWINGS WILL BE COMPLETED BY THE CONTRACTED CONSTRUCTION COMPANY AND ARCHITECTS. IN JULY 2022, BIDDING PERIOD WILL BEGIN FOR CONTRACTORS AND WILL CONCLUDE IN SEPTEMBER 2022. THE WHITE BOX CONSTRUCTION IS PLANNED TO BEGIN IN OCTOBER 2022 AND WILL CONCLUDE IN MAY 2023. THE FIT OUT OF BUILDING WILL BEGIN IMMEDIATELY AFTER THE CONSTRUCTION WRAPS UP. BDCC STAFF WILL BE RESPONSIBLE FOR MANAGING THE TIMELINE’S ACTIVITIES IN PARTNERSHIP WITH THE PROPERTY OWNER AND THE SELECTED CONTRACTOR. BDCC ESTIMATES EQUIPMENT TOTAL COST TO BE $2,013,696. EQUIPMENT PURCHASES INCLUDE: COMMERCIAL-GRADE MICROWAVE, DISPOSALS, REFRIGERATOR, FIXED X-RAY, PORTABLE X-RAY, MAMMOGRAPHY MACHINE, ULTRASOUND MACHINE, COMMERCIAL KITCHEN FIXTURES, MAGNETIC RESONANCE IMAGING (MRI) MACHINE, AND FURNITURE.

USAID FOREIGN ASSISTANCE FOR PROGRAMS OVERSEAS

TRADE ADJUSTMENT ASSISTANCE COMMUNITY COLLEGE AND CAREER TRAINING

EMERGENCY PROVISION OF WATER, SANITATION, HYGIENE, HEALTH, AND NUTRITION SERVICES TO CONFLICT-AFFECTED POPULATIONS IN CETRAL AFRICAN REPUBLIC.

EMERGENCY FOOD ASSISTANCE AND LIVELIHOOD SUPPORT IN EAST REGION OF BURKINA FASO

NOVEL TETRAHEDRON BEAM CT FOR POINT-OF-CARE IMAGING IN EAR, NOSE AND THROAT IMAGING - ABSTRACT POINT-OF-CARE IMAGING IS HIGHLY DESIRED IN OTOLARYNGOLOGIC CLINICS FOR THE DIAGNOSIS OF EAR, NOSE AND THROAT (ENT) DISEASES INCLUDING CANCERS. DUE TO LIMITED IMAGE QUALITY, CURRENT CONE-BEAM CT (CBCT) PRODUCTS ACT NOT AS A SUBSTITUTE BUT RATHER AS A COMPLEMENT TO DIAGNOSTIC MULTI-SLICE CT (MSCT) IN MAXILLOFACIAL AND ENT IMAGING. THE EMERGING MULTI-SOURCE X-RAY SOURCE TECHNOLOGY SUGGESTS NEW DESIGNS OF CT SYSTEMS THAT MAY HAVE FASTER IMAGING SPEED, IMPROVED IMAGE QUALITY, REDUCED RADIATION EXPOSURE, AND COMPACT GEOMETRIES. TETRAHEDRON BEAM COMPUTED TOMOGRAPHY (TBCT) IS A COMPACT VOLUMETRIC CT BASED ON LINEAR ARRAY MULTI- PIXEL X-RAY SOURCES WHICH CAN PRODUCE DIAGNOSTIC-QUALITY VOLUMETRIC IMAGES BUT IN A MUCH MORE COMPACT GEOMETRY THAN CBCT. DURING PHASE I STUDY, WE SUCCESSFULLY DEVELOPED A BENCHTOP ENT-TBCT SYSTEM USING A MULTI-PIXEL THERMIONIC EMISSION X-RAY (MPTEX) SOURCE DEVELOPED IN-HOUSE AND A STATE-OF-ART COMMERCIAL PHOTON-COUNTING DETECTOR (PCD), AND DEMONSTRATED THE SUPERIOR IMAGE QUALITY THAT TBCT CAN ACHIEVE. DURING THE PHASE II STUDY, WE WILL FURTHER REFINE THE MPTEX SOURCE AND DEVELOP A CLINICAL PROTOTYPE SYSTEM. TO ACHIEVE THIS GOAL, WE PROPOSE TO PERFORM STUDIES TO ACHIEVE THE FOLLOWING SPECIFIC AIMS (SA): SA 1: TO DEVELOP A ROTATABLE SEALED MPTEX SOURCE; SA 2: TO DEVELOP A CLINICAL ENT-TBCT PROTOTYPE ON A ROTATING GANTRY; AND SA 3: TO DEVELOP ADVANCED IMAGE RECONSTRUCTION ALGORITHM AND PERFORM BENCHMARK IMAGING STUDIES. THE OUTCOME OF THIS RESEARCH WILL BE A HIGHLY EFFECTIVE POINT-OF-CARE DIAGNOSTIC IMAGING MODALITY FOR OTOLARYNGOLOGIC CLINICS. FUTURE COMMERCIALIZATION OF THE ENT-TBCT SYSTEM WILL IMPROVE THE QUALITY AND EFFICACY BY SUPPORTING PROMPT DIAGNOSIS AND TREATMENT OF ENT CANCERS AND OTHER DISEASES.

TO DELIVER MULTI-SECTOR HUMANITARIAN ASSISTANCE IN CAR.

PREPARE FOR, MITIGATE, AND ADDRESS THE IMPACT OF COVID-19 ON THE SOCIO-ECONOMIC STATUS AND MENTAL WELLBEING OF VULNERABLE REFUGEES AND HOST COMMUNITY MEMBERS IN JORDAN.

EMERGENCY ASSISTANCE TO AFFECTED POPULATION IN THE HAITI EARTHQUAKE.

DESCRIPTION:EPA'S CERCLA SECTION 128(A) GRANT PROGRAM FUNDS ACTIVITIES THAT ESTABLISH OR ENHANCE THE CAPACITY OF STATE AND TRIBAL RESPONSE PROGRAMS. THE GOALS OF THIS FUNDING ARE TO PROVIDE FINANCIAL SUPPORT FOR THE ELEMENTS OF AN EFFECTIVE STATE OR TRIBAL RESPONSE PROGRAM, AS SPECIFIED IN CERCLA SECTION 128, AND TO ENSURE THAT STATES AND TRIBES MAINTAIN A PUBLIC RECORD OF SITES INCLUDED IN THEIR PROGRAMS. THE INFRASTRUCTURE INVESTMENT AND JOBS ACT ('IIJA') PROVIDED ADDITIONAL FUNDING TO CARRY OUT THE SECTION 128(A) GRANT PROGRAM. THE PURPOSE OF THIS AWARD IS TO ENHANCE THE CAPACITY OF THE NATIVE VILLAGE OF NAPAIMUTE'S BROWNFIELDS RESPONSE PROGRAM TO MEET THE SECTION 128(A) ELEMENTS. THE NATIVE VILLAGE OF NAPAIMUTE WILL OVERSEE AND PERFORM PLANNING, ASSESSMENT, AND QAPP PREPARATION. THE NATIVE VILLAGE OF NAPAIMUTE WILL BE HIRING A FIELD TECHNICIAN TO ASSIST WITH BROWNFIELD TASKS AND FIELD WORK IN REMOTE MINING SITES THAT IS PLANNED FOR SPRING/SUMMER 2024. THE NATIVE VILLAGE OF NAPAIMUTE WILL BE ASSESSING THESE REMOTE, ABANDONED MINING SITES TO DETERMINE THE POSSIBLE CONTAMINATION AND ENSURE THAT THEIR VILLAGE AND VILLAGES DOWNSTREAM AREN'T AFFECTED BY THE PERCEIVED LEGACY CONTAMINATION.ACTIVITIES:THE NATIVE VILLAGE OF NAPAIMUTE WILL PERFORM THE FOLLOWING ACTIVITIES: TIMELY SURVEY AND INVENTORY OF BROWNFIELD SITES, WHICH ARE PROPERTIES WHOSE EXPANSION, REDEVELOPMENT, OR REUSE MAY BE COMPLICATED BY THE PRESENCE OF HAZARDOUS SUBSTANCES. IT ALSO INCLUDES OVERSIGHT AND ENFORCEMENT AUTHORITIES TO ENSURE THAT RESPONSE ACTIONS PROTECT HUMAN HEALTH AND THE ENVIRONMENT; RESOURCES TO PROVIDE MEANINGFUL PUBLIC INVOLVEMENT; MECHANISMS FOR APPROVAL OF CLEANUP PLANS, AND VERIFICATION OF COMPLETE RESPONSES. THE OBJECTIVE OF THIS PROJECT IS TO ASSIST IN REMEDIATING AND REUSING BROWNFIELDS SITES THROUGHOUT THE TRIBE'S TRADITIONAL LANDS. SUBRECIPIENT:NO SUBAWARDS ARE INCLUDED IN THIS ASSISTANCE AGREEMENT.OUTCOMES:THE NATIVE VILLAGE OF NAPAIMUTE WILL BEGIN TO INVESTIGATE ABANDONED MINING SITES IN REMOTE AREAS IN THE REGION AND IN NEARBY VILLAGES TO ADDRESS PERCEIVED CONTAMINATION AND TO UPDATE THEIR SITE INVENTORY, PUBLIC RECORD, AND THEIR PRIORITIZED SITES LIST.. THEY WILL MEET WITH COMMUNITY MEMBERS, PROVIDE OUTREACH MATERIALS TO INFORM TRIBAL MEMBERS ABOUT THE PROGRAM, PRESENT INFORMATION AT TRIBAL COUNCIL MEETINGS, AND COORDINATE WITH PARTNER AGENCIES AND ORGANIZATIONS TO CONTINUE TO PROGRESS ON ADDRESSING BROWNFIELDS SITES.

OVC FY17 VOCA VICTIM COMPENSATION FORMULA

VULNERABLE REFUGEES AND HOST COMMUNITIES HAVE IMPROVED RESILIENCE AND ECONOMIC AND MENTAL WELLBEING

WASH CAPACITY BUILDING IN THE MIDDLE EAST.

HUMANITARIAN ASSISTANCE

COMMUNITY CARE OF BROOKLYN NAVIGATOR: ADDRESSING HEALTH EQUITY THROUGH COMMUNITY-BASED BEHAVIORAL HEALTH, SOCIAL SERVICE AND CARE COORDINATION SUPPORT. - PROJECT NAME: COMMUNITY CARE OF BROOKLYN NAVIGATOR: ADDRESSING HEALTH EQUITY THROUGH COMMUNITY-BASED BEHAVIORAL HEALTH, SOCIAL SERVICE AND CARE COORDINATION SUPPORT MAIMONIDES MEDICAL CENTER, IN PARTNERSHIP WITH THE BROOKLYN HEALTH HOME, HAS LAUNCHED THE COMMUNITY CARE OF BROOKLYN (CCB) NAVIGATOR, A CENTRALIZED VIRTUAL NAVIGATION CENTER BRINGING TOGETHER THE MEDICAL, BEHAVIORAL, AND SOCIAL SERVICE PROVIDERS ACROSS OUR NETWORK. THE CCB NAVIGATOR WAS DEVELOPED IN RESPONSE TO A SALIENT NEED TO SIMPLIFY THE PROCESS BY WHICH COMMUNITY MEMBERS ARE CONNECTED TO THE CARE THEY WANT AND NEED. IN HEALTH AND SOCIAL SERVICES SYSTEMS THAT ARE OFTEN SILOED AND FRAGMENTED, IT CAN BE INCREDIBLY CHALLENGING TO A FIND A SERVICE THAT CHECKS ALL THE BOXES: RIGHT TYPE OF CARE, ELIGIBILITY CRITERIA, AND INSURANCE COVERAGE. THE GOAL OF THIS PROJECT IS TO EXPAND CARE MANAGEMENT TO DRIVE OPTIMAL UTILIZATION OF HEALTHCARE AND COMMUNITY RESOURCES, AND USE THIS PROOF OF CONCEPT TO ENGAGE PAYORS IN SUPPORTING CARE MANAGEMENT THAT FALLS OUTSIDE OF EXISTING PAYMENT STREAMS. THE OBJECTIVES ARE: 1) TO COMPLETE THE BUILDOUT OF A CENTRALIZED NAVIGATION RESOURCE FOR INDIVIDUALS, THEIR FAMILIES, AND PROVIDERS UTILIZING A WEB-BASED PLATFORM TO STREAMLINE THE REFERRAL PROCESS AND REDUCE THE ADMINISTRATIVE BURDEN ON THE REFERRING PROVIDERS, 2) DEPLOY A MODEL OF RIGHT-SIZED CARE MANAGEMENT FOR INDIVIDUALS REGARDLESS OF PAYMENT, AND 3) IMPROVE BROOKLYNITES' QUALITY OF LIFE BY REDUCING BARRIERS TO ADDRESS HEALTH EQUITY. THE ANTICIPATED OUTCOMES INCLUDE: 1) INCREASED CONNECTIONS TO COMMUNITY-BASED CARE AND RESOURCES AND 2) INCREASED ENGAGEMENT IN PRIMARY/SPECIALTY/OUTPATIENT PHYSICAL AND BEHAVIORAL HEALTH CARE. THE CCB NAVIGATOR SERVES AS ONE-STOP SHOP FOR ALL REFERRALS WITHIN OUR GROWING NETWORK AND IS COMPRISED OF THREE PRIMARY COMPONENTS: A LIVING GUIDE OF RESOURCES FROM ACROSS THE NETWORK HOUSED IN A WEB-BASED PLATFORM, A PERSON-CENTERED CARE MANAGEMENT NEEDS ASSESSMENT AND MATCHING TOOL, AND THE NAVIGATION CENTER STAFF. THE CCB NAVIGATOR RECEIVES REFERRALS FROM CCB IPA PRACTICES, MAIMONIDES CLINICAL DEPARTMENTS, CBO PARTNERS, OTHER BROOKLYN-BASED HOSPITALS, AND THE COMMUNITY AT-LARGE. NAVIGATORS CONDUCT AN ASSESSMENT WITH PARTICIPANTS OVER THE PHONE, UTILIZING THE MMC TRANSLATION SERVICES AS NEEDED, FOCUSING ON BEHAVIORAL HEALTH AND SOCIAL DETERMINANTS OF HEALTH (FOOD AND HOUSING SECURITY, EMPLOYMENTS, EDUCATION, LEGAL, ETC.) AND, WITH THE SUPPORT OF TRAINED CARE COORDINATORS, CONNECT THEM TO OVER 200 SERVICES ALREADY AVAILABLE IN THEIR COMMUNITY. OUR AIM IN CONDUCTING ASSESSMENTS IS NOT STRICTLY THE COLLECTION OF INFORMATION REGARDING THE PERSON'S HEALTH, BUT ALSO AS A FIRST STEP IN THE DEVELOPMENT OF THE EMPATHETIC AND THERAPEUTIC RELATIONSHIP BETWEEN OUR TEAM AND THE PEOPLE WE SERVE. THE CCB NAVIGATOR AIMS TO DEVELOP AND EMBED AN INTEGRATED APPROACH TO CARE MANAGEMENT THROUGHOUT MAIMONIDES AND THE COMMUNITIES IT SERVES. THROUGH THE CONTINUED COLLABORATION WITH OUR COMMUNITY AND PROVIDER PARTNERS, AND PROVISION OF THIS RESOURCE, THIS INITIATIVE AIMS TO REACH APPROXIMATELY 7000 BROOKLYNITES AND THEIR FAMILIES WITH SIGNIFICANT BEHAVIORAL HEALTH AND SOCIAL NEEDS OVER THE COURSE OF THE PROPOSED FUNDING YEAR. WE WILL SCREEN/ASSESS AT LEAST 50% (3500) OF THE INDIVIDUALS REFERRED TO THE CCB NAVIGATOR AND SUCCESSFULLY CONNECT 75% (2625) OF ASSESSED INDIVIDUALS TO CARE COORDINATION AND/OR COMMUNITY-BASED SERVICES. THE TEAM OF CARE NAVIGATORS WILL FOLLOW UP AND CONFIRM CONNECTION TO CARE FOR ALL INDIVIDUALS ASSESSED AND REFERRED TO CARE.

OVC FY 2021 VOCA COMPENSATION PROGRAM

TAS::89 0222::TAS NEW PHASE I 2010 SBIR; TITLE: A 17 GHZ HIGH GRADIENT LINAC HAVING MOLYBDENUM SURFACES IN THE PEAK ELECTRIC FIELD, DARK CURRENT INT

TEEN PREGNANCY PREVENTION PROGRAM - YOUTHRISE (RESPONSIBILITY, INTEGRITY, SELF-CONTROL = EMPOWERMENT) - NEED FOR THE PROJECT: AIMING FOR HEALTHY FAMILIES (AFHF) IS A COMMUNITY-BASED, NON-PROFIT ORGANIZATION THAT PROPOSES TO IMPLEMENT A TEEN PREGNANCY PREVENTION (TPP) AND POSITIVE YOUTH DEVELOPMENT PROGRAM (PYD). FOR 20 YEARS, AFHF HAS SERVED THOUSANDS OF YOUTH TO PROMOTE PREVENTION INITIATIVES. THE PROJECT NAME IS YOUTH RISE (RESPONSIBILITY, INTEGRITY, SELF-CONTROL = EMPOWERMENT). THE PROJECT WILL SERVE VULNERABLE YOUTH IN RURAL AND UNDER-SERVED COUNTIES IN THE NORTHEAST CORNER OF MISSISSIPPI (MS): LEE, PRENTISS, AND PONTOTOC. IN THESE TARGET COUNTIES NEARLY A QUARTER (22%) OF THE YOUTH LIVE IN POVERTY, COMPARED TO 17% NATIONALLY. ALL THREE COUNTIES HAVE HIGH SCHOOL DROPOUT RATES THAT EXCEED THE NATION’S 6%: LEE-9%, PRENTISS-9 % AND PONTOTOC- 9.2%. SPECIFIC TO TEEN SEXUAL BEHAVIORS, MS RANKS #1 OUT OF 50 STATES WITH THE HIGHEST TEEN BIRTH RATES AND #12 FOR THE MOST SEXUALLY ACTIVE YOUTH. ALL PROJECT TARGET COUNTIES HAVE TEEN BIRTH RATES (PER 1,000) THAT EXCEED THE NATIONAL RATE OF 16.7. TWO OF THE COUNTIES HAVE BIRTH RATES THAT NEARLY DOUBLE, WHILE ONE COUNTY HAS A BIRTH RATE THAT MORE THAN DOUBLES THE NATION: LEE (30.6), AND PRENTISS (29.8) AND PONTOTOC (40.5). MS RANKS AS #1 HAVING THE HIGHEST STD RATE IN THE NATION. PROPOSED SERVICES: THE GOAL OF YOUTH RISE IS TO REDUCE TEEN PREGNANCIES AND STDS/HIV BY EDUCATING YOUTH ON HOW TO VOLUNTARILY REFRAIN FROM RISKY SEXUAL ACTIVITY. THE YOUTH RISE PROGRAM SEEKS TO IMPLEMENT THE FOUR KEY ELEMENTS OF A TPP SCALE-UP PROJECT THAT ARE CRITICAL FOR AN EFFECTIVE TPP PROGRAM: 1) EVIDENCE BASED 2) COMMUNITY MOBILIZATION 3) REFERRALS TO OTHER SERVICES 4) SAFE AND SUPPORTIVE ENVIRONMENTS. THE PROJECT FOCUSES ON ADDRESSING RISK FACTORS AT THE YOUTH, FAMILY, AND COMMUNITY LEVEL. HIGH SCHOOL YOUTH WILL RECEIVE 10 HOURS OF PROPOSED LOVE NOTES 4.0 SRA EBP (LN) AND/OR MIND MATTERS CURRICULUM WITH INCLUSIVE PYD ACTIVITIES. BOTH CURRICULA ARE EVIDENCE BASED AND INCLUDE HEALTHY RELATIONSHIP SKILLS TRAINING. FAMILIES/CAREGIVERS WILL BE ENGAGED IN 60 MINUTES OF PARENT SUPPORT EDUCATION TO STRENGTHEN FAMILY COMMUNICATION. PROJECT COMMUNITY MOBILIZATION ACTIVITIES WILL BE UTILIZED TO STRENGTHEN CAPACITY WITHIN THE TARGET COMMUNITIES. A QUALIFIED EVALUATION TEAM WILL WORK WITH AFHF STAFF TO COLLECT, TRACK, AND MONITOR PERFORMANCE MEASURE DATA AND EVALUATE FIDELITY, QUALITY AND PROGRESS TOWARD PROJECT GOALS AND OBJECTIVES. TARGET POPULATION: THE PROJECT WILL SERVE 850 YOUTH, ANNUALLY, IN LEE, PRENTISS AND PONTOTOC COUNTIES THROUGH A PARTNERSHIP WITH FIVE SCHOOL DISTRICTS: BALDWYN, BOONEVILLE, LEE, PRENTISS, AND PONTOTOC AND OTHER UNIQUE SETTINGS: ADOLESCENT RESIDENTIAL TREATMENT CENTER, FAITH-BASED ORGANIZATION, COMMUNITY MENTAL HEALTH ORGANIZATION SERVING ADOLESCENTS AND JUVENILE DETENTION CENTER/YOUTH COURT. THE PROJECT TARGETS YOUTH AGES 14-18 IN GRADES 9-12. YOUTH OF ALL RACES AND ETHNICITIES WILL PARTICIPATE WITH AN ESTIMATED 30% BEING MINORITY ETHNICITIES. AT LEAST 85 FAMILIES/CAREGIVERS OF PROJECT YOUTH WILL PARTICIPATE IN ACTIVITIES ANNUALLY.

HUMANITARIAN ASSISTANCE

REDUCING COMMUNITY VULNERABILITY IN ZIMBABWE

NATIVE WOMEN'S SOCIETY OF THE GREAT PLAINS

COMMUNITY PROJECT GRANTS CONGRESSIONALLY DELEGATED

DUAL ANTIPLATELET THERAPY TRIAL: RESEARCH PROJECT GRANT (R01)

IMPLEMENTATION OF THE ¿MUJERES DE ORO¿ (WOMEN OF GOLD) GLOBAL DEVELOPMENT ALLIANCE (GDA) ACTIVITY TO PROMOTE A GENDER EQUALITY DEVELOPMENT STRATEGY THROUGH THE POLITICAL, CULTURAL AND ECONOMIC EMPOWERMENT OF WOMEN AND GIRLS IN BAJO CAUCA, ANTIOQUEÑO REGIONS.

THE HENRY MILLER RECLAMATION DISTRICT NO. 2131, LOCATED IN CENTRAL CALIFORNIA, WILL MODERNIZE THE PICK ANDERSON PUMP STATION AT THE NORTH END OF THE DISTRICTS SURFACE WATER CONVEYANCE SYSTEM. THE PROJECT INCLUDES UPGRADING TWO EXISTING SPILL STRUCTURES WITH AUTOMATIC GATES AND FLOW METERS, CONSTRUCTING A LONG-CRESTED WEIR, AND INSTALLING THREE NEW PUMPS. THE PROJECT ALSO INCLUDES LINING 5,560 FEET OF EARTHEN CANALS WITH A GEOMEMBRANE LINER AND CEMENT, AND THREE NEW SUPERVISORY CONTROL AND DATA ACQUISITION SITES FOR REMOTE MONITORING AND AUTOMATED PUMPING CONTROL. THE PROJECT IS EXPECTED TO RESULT IN ANNUAL WATER SAVINGS OF 3,162 ACRE-FEET, CURRENTLY LOST TO SEEPAGE, OVER-PUMPING, AND OPERATIONAL SPILLS. CONSERVED WATER WILL REDUCE THE NEED FOR DEEP WELL PUMPING AND ALLOW WATER TO REMAIN IN THE SAN JOAQUIN RIVER.

HUMANITARIAN ASSISTANCE

EMERGENCY FOOD AND LIVELIHOOD ASSISTANCES IN BURKINA FASO.

STUDENT SUPPORT SERVICES REGULAR PROGRAM

CENTRAL AFRICAN REPUBLIC EMERGENCY FOOD ASSISTANCE PROGRAM AND AGRICULTURAL RECOVERY FOR CONFLICT AFFECTED POPULATIONS

SYNTHOPLATE-ENRICHED PLASMA FOR ENHANCED HEMOSTATIC RESUSCITATION IN TRAUMA

TO SUPPORT DROUGHT-AFFECTED POPULATIONS IN MADAGASCAR WITH AGRICULTURE, NUTRITION, AND WATER ASSISTANCE.

HEAVY TRUCK ENGINE PROGRAM

OVC FY 09 VOCA VICTIM COMPENSATION FORMULA GRANT

ENGLISH LANGUAGE ACQUISITION: NATIONAL PROFESSIONAL DEVELOPMENT PROGRAM

STUDENT SUPPORT SERVICES STEM PROGRAM

YOUTH RISE (RESPONSIBILITY, INTEGRITY, SELF-CONTROL = EMPOWERMENT)

GRANT TO IMC FOR HEALTH, NUTRITION, PROTECTION IN CHAD

AMERICAN RESCUE PLAN ACT FUNDING FOR HEALTH CENTERS

KOOPMAN OPERATOR THEORETIC METHODS FOR EFFICIENT TRAINING AND ANALYSIS OF DEEP NEURAL NETWORKS

LIGHT-DUTY FUEL CELL ELECTRIC VEHICLE VALIDATION DATA

SEXUAL RISK AVOIDANCE EDUCATION PROGRAM - YOUTH RISE

NON-OPIOID PAIN MANAGEMENT INITIATIVE IN THE EMERGENCY DEPARTMENT.

STUDENT SUPPORT SERVICES PROGRAM

TO PROVIDE EMERGENCY NUTRITION, HEALTH, WATER, SANITATION & HYGIENE RESPONSE FOR CONFLICT-AFFECTED POPULATIONS IN CENTRAL AFRICAN REPUBLIC.

THE SEXUAL RISK AVOIDANCE EDUCATION (SRAE) PROGRAM

STUDENT SUPPORT SERVICES PROGRAM

EMERGENCY NUTRITION, CHILD CARE PRACTICES/IYCF REINFORCEMENT AND PSYCHOSOCIAL SUPPORT TO SOUTH SUDANESE REFUGEES & HOST COMMUNITY IN GAMBELLA

HUMANITARIAN ASSISTANCE

STUDENT SUPPORT SERVICES PROGRAM

HIGHER EDUCATION EMERGENCY RELIEF FUND ASSISTING STUDENTS AND INSTITUTIONS AFFECTED BY COVID-19.

TAS::57 3600::TAS 'ANALYSIS OF SPATIALLY EXTENDED DYNAMICAL SYSTEMS WITH APPLICATIONS TO AGENT-BASED MODELS'

FIELD SUPPORT TEAM FOR WASH HUMANITARIAN RESPONSE

STUDENT SUPPORT SERVICES PROGRAM

AWARDING AGENCY: U.S. AGENCY FOR INTERNATIONAL DEVELOPMENT CFDA LISTING / ASSISTANCE LISTING: 98.008 - USAID FOOD FOR PEACE EMERGENCY PROGRAM CFDA NARRATIVE EXCERPT: THE PURPOSE OF USAID’S BUREAU FOR HUMANITARIAN ASSISTANCE (BHA) FOOD FOR PEACE EMERGENCY PROGRAM (EP) IS TO PROVIDE LIFE-SAVING HUMANITARIAN ASSISTANCE—TO IMPROVE ACCESS, AVAILABILITY OF FOOD IN FOOD INSECURE ENVIRONMENTS AND HARDEST-TO-REACH POPULATION AFFECTED BY NATURAL, MAN-MADE AND COMPLEX DISASTER. THE PRIORITY OF TITLE II EMERGENCY PROGRAMS IS TO PREVENT HUNGER AND MALNUTRITION IN FOOD INSECURE AREAS IN AFFECTED COUNTRIES. BHA IS THE LEAD FEDERAL COORDINATOR FOR INTERNATIONAL DISASTER ASSISTANCE, HARNESSING THE EXPERTISE AND UNIQUE CAPACITIES OF OTHER U.S., NON-U.S. ENTITIES & PUBLIC INTERNATIONAL ORGANIZATIONS (PIOS) TO EFFECTIVELY RESPOND TO NATURAL DISASTERS, COMPLEX CRISES BY PROVIDING EMERGENCY AND FOOD ASSISTANCE AROUND THE WORLD. RECIPIENT – ACTION CONTRE LA FAIM (ACF) THE PURPOSE OF THIS AWARD IS TO PROVIDE FINANCIAL SUPPORT TO ACF’S PROGRAM IN NIGERIA. USAID FUNDS UNDER THIS AWARD WILL BE USED TO PROVIDE A CONTRIBUTION OF IN-KIND (EMERGENCY FD, RUTF SPRD POUCH-150/92 G) TO ACF IN NIGERIA FOR 15 MONTHS. THIS AWARD CONTAINS A CASH COMPONENT AND AN IN-KIND COMPONENT. USAID FUNDS UNDER THE AWARD WILL ONLY BE USED FOR THE APPROVED ITSH AND SECTION 202(E) FUNDING LEVEL OF $1,010,065. OF THIS, $370,894 WILL BE PROVIDED IN ITSH AND $639,171 WILL BE PROVIDED IN SECTION 202(E) RESOURCES. USAID’S IN-KIND CONTRIBUTION OF 1,031 MT OF EMERGENCY FD, RUTF SPRD POUCH-150/92 G VALUED AT $3,489,935 (INCLUDING $3,257,960 IN COMMODITY VALUE, AND $231,975 FOR OCEAN FREIGHT).

HUMANITARIAN ASSISTANCE

HEALTH INFRASTRUCTURE INVESTMENT PROGRAM

ECONOMIC DEVELOPMENT INITIATIVE, COMMUNITY PROJECT FUNDING, AND MISCELLANEOUS GRANTS

TO PROVIDE WATER SANITATION AND HYGIENE PROMOTION FOR INTERNALLY DISPLACE PERSONS AND THEIR HOST COMMUNITY IN EASTERN CHAD.

HUMANITARIAN ASSISTANCE

MYHEALTHYPREGNANCY MOBILE HEALTH APP: COMBINING BEHAVIORAL SCIENCE AND MACHINE LEARNING FOR RISK COMMUNICATION DURING THE PERIPARTUM PERIOD

RESPONSE TO NUTRITIONAL EMERGENCY, BAHR EL GAZEL REGION, CHAD.

COVID ASSISTANCE

HUMANITARIAN ASSISTANCE

CONTRIBUTE TO THE REDUCTION OF THE RISK OF MORBIDITY, MORTALITY AMONGST SOUTH SUDANESE REFUGEES AND HOST COMMUNITY POPULATION IN GAMBELLA.

EMERGENCY WATER, SNAITATION AND HYGIENE RESPONSE FOR RESIDENTS, IDPS AND RETURNED POPULATION AFFECTED BY THE HUMANITARIAN CRISIS IN BOSSANGOA, CAR

SUPPORT SOUTH SUDANESE REFUGEES AND HOST COMMUNITY POPULATION IN GAMBELLA AND BENISHANGUL GUMUZ REGIONS.

GOBBLEFIELD DITCH PIPING AND EPHRAIM TUNNEL IMPROVEMENTS

YOUTH RISE - RESPONSIBILITY, INTEGRITY, SELF-CONTROL = EMPOWERMENT: A SEXUAL RISK AVOIDANCE EDUCATION PROGRAM

OVC FY 19 VOCA VICTIM COMPENSATION FORMULA

THE NATIVE VILLAGE OF PAIMIUT IS A FEDERALLY RECOGNIZED AND DISPLACED TRIBE ON THE SOUTHWESTERN BERING SEA COAST. THE NATIVE VILLAGE OF PAIMIUT IS BECOMING A REGIONAL LEADER AND INNOVATOR IN ALASKA ON TRIBAL JUSTICE AND TECHNICAL ASSISTANCE FOR OTHER TRIBES, TRIBAL COURTS, AND INTERAGENCY AGREEMENTS AND PARTNERSHIPS. THE SHORTAGE OF LAW ENFORCEMENT AND PUBLIC SAFETY STAFF HAS BECOME ENDEMIC IN RURAL ALASKA AND NEEDS ADDRESSING. PARTNERSHIPS LIKE OURS WILL BECOME THE NORM. IN ADDITION, WE FEEL THAT ALL FEDERAL AGENCIES SHOULD LOOK TO INNOVATIVE COMMUNITY-BASED, INTERTRIBAL AND INTERAGENCY SOLUTIONS LIKE OURS. THE NATIVE VILLAGE OF PAIMIUT IS APPLYING FOR FUNDING ON BEHALF OF THE TRIBE AS WELL AS ITS PARTNER IN LAW ENFORCEMENT, THE CITY OF HOOPER BAY VILLAGE POLICE OFFICER PROGRAM. GRANT FUNDS WILL BE USED TO EXPAND AND FACILITATE ADDITIONAL PROGRAMS, SERVICES, AND TRAINING, AND CHILD AND FAMILY COUNSELING WILL TO ENSURE WE CAN MEET TRIBAL JUSTICE AND PUBLIC SAFETY PRIORITIES WITHIN THE SHARED COMMUNITY OF HOOPER BAY.

SBIR PHASE II: MANUFACTURING AND CHARACTERIZATION OF A SYNTHETIC PLATELET (SYNTHOPLATETM) TECHNOLOGY

RENOVATION OF THE WHITE MOUNTIAN APACHE TRIBES DETENTION CENTER

A NOVEL PLATELET-INSPIRED NANOTECHNOLOGY TO RESTORE HEMOSTASIS IN PATIENTS ON ANTIPLATELET AGENTS - PROJECT SUMMARY/ABSTRACT ANTIPLATELET THERAPY WITH P2Y12 INHIBITORS (CLOPIDOGREL, TICAGRELOR ETC.) IS WIDELY USED TO PREVENT THROMBOTIC EVENTS IN PATIENTS WITH CARDIOVASCULAR DISEASE. HOWEVER, THESE AGENTS SIGNIFICANTLY INCREASE THE RISK OF BLEEDING COMPLICATIONS, IMPACTING OVER 1.4 MILLION LIVES ANNUALLY IN THE UNITED STATES. THE LACK OF SPECIFIC REVERSAL AGENTS OFTEN LEADS TO DELAYED SURGICAL INTERVENTIONS AND SIGNIFICANT COMPLICATIONS, INCLUDING INCREASED TRANSFUSIONS, IN- HOSPITAL COMPLICATIONS, HIGHER MORTALITY, AND PROLONGED HOSPITAL STAYS. BLEEDING MANAGEMENT IS PARTICULARLY PROBLEMATIC IN PATIENTS WITH TRAUMATIC BRAIN INJURY (TBI), WITH 10-31% OF TBI PATIENTS TAKING P2Y12 INHIBITORS PRIOR TO ADMISSION. TBI PATIENTS ON P2Y12 INHIBITORS HAVE A SIGNIFICANTLY INCREASED RISK OF INTRACRANIAL HEMORRHAGE AND MORTALITY, WITH A 50-60% INCREASED RISK OF SEVERE BLEEDING AND A 6-8-FOLD INCREASED 30-DAY MORTALITY WHEN REVERSAL OF ANTIPLATELET THERAPY IS NOT POSSIBLE. CURRENT HEMOSTATIC AGENTS, SUCH AS PROTHROMBIN COMPLEX CONCENTRATES, FIBRINOGEN CONCENTRATES, AND RECOMBINANT ACTIVATED FACTOR VII, ARE INEFFECTIVE IN RESCUING HEMOSTASIS IN THE PRESENCE OF P2Y12 INHIBITORS, LEAVING PLATELET TRANSFUSIONS AS THE ONLY STANDARD OF CARE. HOWEVER, PLATELET TRANSFUSIONS HAVE SIGNIFICANT LIMITATIONS, INCLUDING LIMITED EFFICACY, DONOR DEPENDENCE, SHORT SHELF-LIFE, IMMUNE RESPONSES, AND REFRACTORINESS. THERE IS A CRITICAL UNMET NEED FOR A READILY AVAILABLE, DONOR- INDEPENDENT THERAPEUTIC THAT CAN EFFECTIVELY RESTORE HEMOSTATIC FUNCTION IN TBI PATIENTS ON P2Y12 INHIBITORS. WE HYPOTHESIZE THAT SYNTHOPLATE (SP), A PLATELET-INSPIRED SYNTHETIC HEMOSTATIC NANOPARTICLE, CAN RESTORE HEMOSTASIS IN TBI PATIENTS ON P2Y12 INHIBITORS BY ENHANCING PLATELET ADHESION AND AGGREGATION AT THE INJURY SITE, THEREBY REDUCING HEMORRHAGE AND MORTALITY. OUR PRELIMINARY DATA DEMONSTRATE SP'S EFFICACY IN IMPROVING CLOT FORMATION UNDER P2Y12 INHIBITION IN VITRO, REDUCING BLEEDING BY 80%, AND ENHANCING SURVIVAL IN PRECLINICAL MODELS OF P2Y12 INHIBITOR-INDUCED HEMORRHAGE. AIM 1 WILL ESTABLISH SP'S DOSE-RESPONSE RELATIONSHIP IN CLINICALLY RELEVANT RAT MODELS OF P2Y12 INHIBITOR-INDUCED BLEEDING, INCLUDING TBI, EXAMINING BLOOD LOSS, HEMODYNAMICS, PLATELET FUNCTION, HEMOSTATIC OUTPUT AND NEUROLOGICAL OUTCOMES. AIM 2 WILL DETERMINE SP'S SAFETY PROFILE, PHARMACOKINETICS, AND ANY DRUG-DRUG INTERACTIONS IN THE PRESENCE OF P2Y12 INHIBITORS, IDENTIFYING THE THERAPEUTIC WINDOW AND INFORMING CLINICAL DOSING STRATEGIES. AIM 3 WILL DEVELOP A COMPREHENSIVE CLINICAL DEVELOPMENT PLAN, DEFINING THE REGULATORY PATHWAY, AND PHASE 1 TRIAL DESIGN FOR THE TARGET TBI POPULATION. THIS WORK WILL DELIVER A ROBUST PRECLINICAL EFFICACY, SAFETY, AND PHARMACOKINETIC PACKAGE, AND A STRATEGIC CLINICAL ROADMAP TO ADVANCE SP TO IND FILING AND CLINICAL EVALUATION IN THIS VULNERABLE TBI POPULATION WITH A SUBSTANTIAL UNMET NEED. BY REDUCING INTRACRANIAL HEMORRHAGE AND MORTALITY, SP HAS THE POTENTIAL TO TRANSFORM MANAGEMENT OF TBI IN THE SETTING OF P2Y12 INHIBITORS AND SIGNIFICANTLY IMPROVE PATIENT OUTCOMES. ESTABLISHING PROOF-OF-CONCEPT IN TBI WILL ENABLE FUTURE EXPANSION TO OTHER INDICATIONS WHERE P2Y12 INHIBITOR-ASSOCIATED BLEEDING IS A MAJOR CONCERN.

NUTRITIONAL AND PSYCHOSOCIAL SUPPORT FOR THE SOUTH SUDANESE REFUGEES IN GAMBELLA REGION, ETHIOPIA

HIGHER EDUCATION EMERGENCY RELIEF FUND ASSISTING STUDENTS AND INSTITUTIONS AFFECTED BY COVID-19.

A CHOPPERTON RF SOURCE FOR HIGH GRADIENT ACCELERATOR RESEARCH

TRIO - STUDENT SUPPORT SERVICES - STUDENT SUPPORT SERVICES PROGRAM

NEW AWARD (GRANT) TO ACTION CONTRE LA FAIM (ACF) TO SUPPORT THE IMPLEMENTATION OF AGRICULTURE & FOOD SECURITY AND WASH PROGRAM ENTITLED, "MULTISECTOR EMERGENCY INTERVENTION FOR VULNERABLE ZIMBABWEANS AFFECTED BY PROTRACTED DROUGHT AND SOCIOECONOMIC CRISIS" IN ZIMBABWE.

THIS AWARD WILL PROVIDE HEALTH AND WASH SERVICES TO COVID-19 AFFECTED POPULATIONS.

BUILD RESPONSE CAPACITY IN NUTRITION ON BOGANDE AND MANNE DISTRICTS IN BURKINA FASO

HUMANITARIAN ASSISTANCE

YOUTH RISE (RESPONSIBILITY, INTEGRITY, SELF-CONTROL = EMPOWERMENT)

MAM'OUT PROJECT: EVALUATION OF INNOVATIVE APPROACHES TO PREVENT ACUTE MALNUTRITIO

IMPROVE EXISTING AIRPORT

THE GRANT AWARD PROVIDES FUNDS FROM THE CRIME VICTIMS FUND TO ENHANCE STATE VICTIM COMPENSATION PAYMENTS TO ELIGIBLE CRIME VICTIMS. VICTIMS OF CRIME ACT (VOCA) COMPENSATION FUNDS PROVIDE FINANCIAL ASSISTANCE TO FEDERAL AND STATE VICTIMS OF CRIME. NC/NCF

NUTRITION PROGRAM IN CHAD

INDIAN COMMUNITY DEVELOPMENT BLOCK GRANT (ICDBG)

YOUTH RISE - RESPONSIBILITY, INTEGRITY, SELF-CONTROL = EMPOWERMENT: A TEEN PREGNANCY PREVENTION PROGRAM

COVID19 RELATED EXPENSES

THIS GRANT PROGRAM SUPPORTS THE DEVELOPMENT AND OPERATION OF NONPROFIT, NONGOVERNMENTAL TRIBAL DOMESTIC VIOLENCE, AND SEXUAL ASSAULT COALITIONS. RECOGNIZED TRIBAL COALITIONS MAY USE FUNDING FROM THE TRIBAL COALITIONS PROGRAM TO: 1) INCREASE AWARENESS OF DOMESTIC VIOLENCE AND SEXUAL ASSAULT AGAINST INDIAN OR NATIVE HAWAIIAN WOMEN; 2) ENHANCE THE RESPONSE TO VIOLENCE AGAINST INDIAN OR NATIVE HAWAIIAN WOMEN AT THE FEDERAL, STATE, AND TRIBAL LEVELS; 3) IDENTIFY AND PROVIDE TECHNICAL ASSISTANCE TO COALITION MEMBERSHIP AND TRIBAL COMMUNITIES OR NATIVE HAWAIIAN COMMUNITIES TO ENHANCE ACCESS TO ESSENTIAL SERVICES TO INDIAN OR NATIVE HAWAIIAN WOMEN VICTIMIZED BY DOMESTIC AND SEXUAL VIOLENCE, INCLUDING SEX TRAFFICKING; AND 4) ASSIST INDIAN TRIBES OR NATIVE HAWAIIAN COMMUNITIES IN DEVELOPING AND PROMOTING STATE, LOCAL, AND TRIBAL LEGISLATION AND POLICIES THAT ENHANCE BEST PRACTICES FOR RESPONDING TO VIOLENT CRIMES AGAINST INDIAN OR NATIVE HAWAIIAN WOMEN, INCLUDING THE CRIMES OF DOMESTIC VIOLENCE, DATING VIOLENCE, SEXUAL ASSAULT, SEX TRAFFICKING, AND STALKING. WITH THIS FUNDING, THE NATIVE WOMEN'S SOCIETY OF THE GREAT PLAINS (NWSGP) INCLUDES MEMBERSHIP ORIGINATING FROM THE 30 TRIBES LOCATED IN THE ORIGINAL BOUNDARIES OF THE GREAT SIOUX NATION. NWSGP WILL SERVE 9 FEDERALLY RECOGNIZED TRIBES IN SOUTH DAKOTA AS WELL AS TRIBAL COMMUNITIES LOCATED IN RURAL, SUBURBAN, AND THE URBAN AREAS. NWSGP WILL PROVIDE MEMBERS, ALLIES, AND TRIBAL GOVERNMENTS WITH SERVICES, TRAINING AND TECHNICAL ASSISTANCE SUPPORT FOR CAPACITY BUILDING, EDUCATION, PREVENTION, PUBLIC AWARENESS, POLICY AND SYSTEMS CHANGE, AND INFORMATION TO COMBAT DOMESTIC VIOLENCE, SEXUAL ASSAULT AND TRAFFICKING OF NATIVE WOMEN.NWSGP WILL 1.) INCREASE THE CAPACITY AND STABILITY OF MEMBER ORGANIZATIONS TO PROVIDE ADVOCACY AND RELATED SERVICES TO WOMEN VICTIMS BY DOMESTIC VIOLENCE, SEXUAL ASSAULT, DATING VIOLENCE AND STALKING IN THEIR RESPECTIVE TRIBAL COMMUNITIES BY SUPPORTING AND ENHANCING THE KNOWLEDGE AND SKILLS OF STAFF AND PROVIDING NETWORKING AMONG MEMBERS; 2.) PROVIDE TRAINING AND TECHNICAL ASSISTANCE TO MEMBER ORGANIZATIONS; 3) PROVIDE TRAINING TO LAW ENFORCEMENT, HEALTH PROFESSIONALS AND PROGRAM STAFF IN THE AREA OF SEXUAL ASSAULT SO THAT A COORDINATED COMMUNITY RESPONSE CAN BE IDENTIFIED IN EACH COMMUNITY; AND 4.) PROVIDE PUBLIC EDUCATION AND ENHANCE AWARENESS IN THE LOCAL COMMUNITIES ON DOMESTIC VIOLENCE, SEXUAL ASSAULT, STALKING AND DATING VIOLENCE AND HOW TO ACCESS SERVICES FOR VICTIMS. THE TIMING FOR PERFORMANCE OF THIS AWARD IS 12 MONTHS.

GRADIENT ENHANCEMENT RESEARCH FOR LINEAR ACCELERATOR STRUCTURES

PESBART: EFFECTS OF PHYSICAL ENVIRONMENT AND STRESS IN BLACKS IN RELATION TO ASTH

INCREASE OUTREACH, EXPAND TRAINING TO VETERANS, HAWAIIANS, AND ECONOMICALLY DISADVANTAGED POPULATION

HIGHER EDUCATION EMERGENCY RELIEF FUND ASSISTING STUDENTS AND INSTITUTIONS AFFECTED BY COVID-19.

FISCAL YEAR 2017 CONSOLIDATED GRANT PROGRAM TO ADDRESS CHILDREN AND YOUTH EXPERIENCING DOMESTIC AND SEXUAL ASSAULT AND ENGAGE MEN AND BOYS AS ALLIES

HUMANITARIAN ASSISTANCE

IMPROVE EXISTING AIRPORT

NUTRITIONAL AND PSYCHOCIAL SUPPORT FOR THE REGISTERED REFUGEE CAMPS IN KUTUPALONG AND NAYAPARA AND SURROUNDING COMMUNITIES IN UKIAH AND TEKNAF UPAZIL

INTEGRATED WASH & NUTRITION RESPONSE TO DROUGHT IN SOUTHERN OF MADAGASCAR

HEERF SAARP GRANT FOR UNDERFUNDED INSTITUTION, NOT RECEIVED FAIR ALLOCATION OF HEERF III

THE BROOKLYN PARENTING CENTER - THE BROOKLYN PARENTING CENTER WILL ADDRESS THE LACK OF COMPREHENSIVE INTEGRATED DEVELOPMENTAL, BEHAVIORAL AND MENTAL HEALTH SERVICES FOR FAMILIES DURING THE FIRST THOUSAND DAYS OF LIFE, FROM CONCEPTION TO AGE 2, IN THE BOROUGH OF BROOKLYN, NEW YORK. TO ADDRESS THIS GAP IN SERVICES, THE BROOKLYN PARENTING CENTER WILL OFFER AN INNOVATIVE, RESILIENCE-BASED PROGRAM FOR FAMILIES AND OUR SURROUNDING COMMUNITIES. THIS PROGRAM INTEGRATES A TRAUMA INFORMED PSYCHOSOCIAL APPROACH TO FAMILIES FROM CONCEPTION WITHIN THE OBGYN OFFICE, THE POSTPARTUM RECOVERY UNIT AND THE PEDIATRIC PRIMARY CARE SETTING, AND AIMS TO EXPAND ACCESS TO EARLY CHILDHOOD AND PARENTAL MENTAL HEALTH SERVICES TO A VULNERABLE POPULATION OF CHILDREN AND FAMILIES WHO ARE AT RISK OF ADVERSE HEALTH OUTCOMES. ADDITIONALLY, THE BROOKLYN PARENTING CENTER WILL IDENTIFY AND ADDRESS PSYCHOSOCIAL RISK FACTORS THROUGH ROUTINE SOCIAL NEEDS SCREENING AND REFERRALS TO COMMUNITY-BASED PARTNERS. THE PARENTING CENTER AIMS TO BEGIN UPSTREAM AT CONCEPTION AND FOLLOW A FAMILY THROUGH THE CTICIAL PERIOD OF BRAIN DEVELOPMENT IN THE FIRST TWO YEARS OF LIFE. THE GOALS OF THE PROJECT INCLUDE 1)INCREASE THE CAPACITY OF MAIMONIDES HOSPITAL TO REDUCE UNMET SOCIAL AND EMOTIONAL NEEDS IN THE FIRST THOUSAND DAYS OF LIFE, 2) DECREASE MATERNAL PERINATAL MOOD DISORDERS BY INTEGRATING A PREVENTIVE MODEL OF PSYCHOSOCIAL CARE WITH CLINICAL MENTAL HEALTH SPECIALISTS IN THE FIRST THOUSAND DAYS, AND 3) CONNECT FAMILIES TO LOCAL COMMUNITY BASED ORGANIZATIONS THAT ARE ABLE TO ADDRESS UNMET SOCIAL NEEDS IN THE FIRST THOUSAND DAYS OF LIFE. THE OBJECTIVES OF THE PROJECT ARE TO 1) SCREEN 80% OF PATIENTS IN THE PRENATAL PERIOD (80% OF 1500=1200 PATIENTS) AND 80% OF PATIENTS IN THE POSTPARTUM PERIOD (80% OF 6,660=5280) FOR A) SOCIAL NEEDS, B) MENTAL HEALTH AND C) ADVERSE CHILDHOOD EXPERIENCES, 2) ENROLL 1,000 FAMILIES IN THE BROOKLYN PARENTING CENTER BY PROVIDING INTEGRATED MENTAL HEALTH IN THE PRENATAL, POSTPARTUM AND INFANT PERIOD WITH CLINICAL MENTAL HEALTH PROVIDERS, AND 3) REFER 500 FAMILIES TO COMMUNITY BASED ORGANIZATIONS BASED ON NEEDS ASSESSED THROUGH SCREENING TOOLS

GRADIENT ENHANCEMENT RESEARCH FOR LINEAR ACCELERATOR STRUCTURES

ADDRESSING UNDERNUTRITION AND WASH NEEDS DURING EL NINO INDUCED DROUGHT IN ZIMBABWE

ENVIRONMENTAL COMPLIANCE, ENGINEERING AND DESIGN FOR THE ARROYO CANAL FISH SCREEN AND SACK DAM FISH PASSAGE PROJECT

NATIVE VILLAGE OF NAPAIMUTE FUNDING FOR PARTNERS FOR FISHERIES MONITORING PROGRAM

"METAMODEL ANALYSIS FOR AGENT-BASED MODELS: SCALES, UNCERTAINTY, DATA ANALYSIS", JAN 08

THE PURPOSE OF THE ACTIVITY IS TO CONTRIBUTE TO RECONCILIATION AMONG VICTIMS, EX-COMBATANTS, AND HOST COMMUNITIES IN FOUR MUNICIPALITIES AFFECTED BY CONFLICT BY STRENGTHENING ATTITUDES AND SKILLS ASSOCIATED WITH A CULTURE OF PEACE AND A PACIFIC COEXISTENCE.

THE PURPOSE OF THIS AWARD IS TO PROVIDE ACF/F FUNDING IN THE AMOUNT OF $622 594.00 OVER A 10 MONTH PERIOD EFFECT UPON THE AGREEMENT OFFICER'S SIGNATU

SOUTHWEST WELL CONSTRUCTION AND WATER DELIVERY INFRASTRUCTURE

DEVELOPMENT OF A NOVEL INJECTABLE ANTIBIOTIC TO TREAT SERIOUS MULTIDRUG-RESISTANT GRAM-POSITIVE INFECTIONS - PROJECT SUMMARY / ABSTRACT WITHIN THE PAST DECADES, THE PREVALENCE OF ANTIBIOTIC-RESISTANT (AMR) GRAM-POSITIVE INFECTIONS HAVE INCREASED, AND GRAM-POSITIVE BACTERIA CAUSE THE MAJORITY OF NOSOCOMIAL INFECTIONS. IT WAS ESTIMATED THAT IN 2019 THERE WERE 4.95 MILLION DEATHS ASSOCIATED WITH AMR AND 1.27 MILLION DEATHS DIRECTLY ATTRIBUTABLE TO AMR. IN HIGH INCOME COUNTRIES, STAPHYLOCOCCUS AUREUS WAS THE MOST FREQUENT PATHOGEN, ACCOUNTING FOR 26.1% OF THE DEATHS ATTRIBUTABLE TO AMR. TWO OF THE MOST PREVALENT AND/OR DIFFICULT-TO-TREAT PATHOGENS INCLUDE METHICILLIN RESISTANT S. AUREUS (MRSA) AND VANCOMYCIN-RESISTANT ENTEROCOCCUS (VRE); BOTH ARE ON THE LIST OF WHO AND CDC PRIORITY PATHOGENS WHICH INFORMS THE VITAL NEED FOR NEW AND EFFECTIVE ANTIBIOTICS. UNFORTUNATELY, THESE PATHOGENS CONTINUE TO DEVELOP NEW MULTI-DRUG RESISTANCE PATTERNS REDUCING THERAPEUTIC OPTIONS. FURTHERMORE, THE COVID- 19 PANDEMIC HAS SIGNIFICANTLY INCREASED THE RATES OF ANTIMICROBIAL RESISTANCE, AND NOVEL THERAPEUTICS WILL BE NEEDED IN THE FUTURE TO COMBAT THESE SERIOUS AND PREVALENT HOSPITAL ACQUIRED INFECTIONS. AIMMAX THERAPEUTICS HAS DISCOVERED A NOVEL ANTIBIOTIC, AMX-2005, WITH BROAD SPECTRUM AND BEST-IN-CLASS ACTIVITY AGAINST MRSA AND VRE WITH POTENCY SUPERIOR TO LINEZOLID AND NO CROSS-RESISTANCE TO VANCOMYCIN. THIS ANTIBIOTIC HAS DEMONSTRATED RAPID BACTERICIDAL ACTIVITY IN IN VITRO TIME-KILL ASSAYS AT CONCENTRATIONS AS LOW AS 2X THE MIC AS WELL AS BACTERICIDAL EFFICACY IN THE IN VIVO MURINE NEUTROPENIC THIGH INFECTION MODEL. AMX-2005 SHOWS THE POTENTIAL TO BE A NEXT GENERATION THERAPEUTIC FROM A CLASS WITH AN ESTABLISHED HISTORY OF CLINICAL SAFETY AND LOW RATES OF RESISTANCE. COLLECTIVELY, THESE DATA PROVIDE A STRONG FOUNDATION OF SUPPORT FOR THIS PROPOSAL. THE OVERALL GOAL OF THIS PROPOSED PHASE 1 SBIR APPLICATION IS TO DEVELOP A NOVEL INTRAVENOUS FORMULATION OF AMX-2005 AND GENERATE PROOF-OF-CONCEPT DATA TO SUPPORT THE DEVELOPMENT OF A THERAPEUTIC FOR DIFFICULT-TO-TREAT INDICATIONS WITH HIGH UNMET NEEDS. IN AIM 1, WE WILL CONDUCT FURTHER IN VITRO MICROBIOLOGY STUDIES TO INVESTIGATE ACTIVITY AND ATTRIBUTES ESSENTIAL TO SUCCESSFUL THERAPEUTICS FOR SERIOUS INFECTIONS, INCLUDING AN EVALUATION OF THE POTENTIAL FOR RESISTANCE DEVELOPMENT. IN AIM 2, WE WILL DEVELOP A NOVEL IV FORMULATION OF AMX-2005 THROUGH THE USE OF INNOVATIVE MODERN EXCIPIENTS AND FORMULATION TECHNOLOGY. OUR TOP TWO FORMULATIONS WILL THEN UNDERGO RIGOROUS SAFETY ASSESSMENTS INCLUDING IN VITRO COMPATIBILITY TESTS WITH PLASMA AND BLOOD, VEIN IRRITATION STUDY AT THE INJECTION SITE TO ENSURE SAFETY AND TOLERABILITY OF THE LEAD IV FORMULATION, FOLLOWED BY DETERMINATION OF MAXIMUM TOLERATED DOSE IN MICE. THE PK PROFILES OF THE TOP FORMULATION WILL BE ASSESSED TO DETERMINE THE MOST SUITABLE DOSING REGIMENS FOR EFFICACY STUDIES IN AIM 3, WHERE WE WILL ASSESS THE ACTIVITY AND POTENCY OF FORMULATED IV AMX-2005 IN MICE MODELS OF SEPTICEMIA AND THIGH INFECTION AGAINST MDR STRAINS OF MRSA OR VRE. FINALLY, WE WILL CONDUCT A MOUSE PK STUDY TO ASSESS TISSUE CONCENTRATIONS OF AMX-2005. IF SUCCESSFUL, THESE DATA WILL INFORM INDICATION SELECTION AND A TARGET PRODUCT PROFILE TO SUPPORT A SUBSEQUENT PHASE 2 SBIR APPLICATION IN WHICH BOTH IV AND ORAL DOSAGE FORMS OF AMX-2005 WILL BE DEVELOPED.

NUTRITIONAL AND MENTAL HEALTH SUPPORT FOR THE REGISTERED REFUGEE CAMPS IN KUTUPALONG AND NAYAPARA AND SURROUNDING VULNERABLE COMMUNITIES IN UKIAH AND

OPTIMIZATION AND CHARACTERIZATION OF NOVEL ANTIFUNGAL PEPTIDES - PROJECT SUMMARY / ABSTRACT INVASIVE CANDIDIASIS IS A DISEASE ASSOCIATED WITH SIGNIFICANT MORBIDITY AND MORTALITY, WITH ONLY 3 CLASSES OF ANTIFUNGALS AVAILABLE FOR TREATMENT. WHILE CANDIDA ALBICANS REMAINS THE MOST COMMON SPECIES ASSOCIATED WITH THIS DISEASE, OTHER NON-ALBICANS CANDIDA SPECIES ARE EMERGING OR GROWING IN PREVALENCE. THE GLOBAL EMERGENCE OF CANDIDA AURIS, A SPECIES WITH A HIGH RATE OF MULTI-DRUG RESISTANCE CAPABLE OF NOSOCOMIAL TRANSMISSION, AND REPORTS OF CANDIDA GLABRATA INFECTIONS RESISTANT TO BOTH AZOLES AND ECHINOCANDINS, HIGHLIGHT THE CRITICAL NEED FOR NEW CLASSES OF ANTIFUNGAL DRUGS THAT CAN COMBAT RESISTANCE AND TREAT INVASIVE FUNGAL DISEASES. AIMMAX THERAPEUTICS IS DEVELOPING A NOVEL CLASS OF PROMISING ANTIFUNGAL PEPTIDES THAT ARE DIFFERENTIATED FROM OTHER ANTIMICROBIAL PEPTIDES IN DEVELOPMENT. PEPTIDES HAVE BEEN CONSIDERED AS PROMISING THERAPEUTICS BECAUSE OF THEIR NOVEL MECHANISMS OF ACTION, RAPID CIDALITY, LOW PROPENSITY FOR RESISTANCE DEVELOPMENT AND LOW POTENTIAL FOR DRUG-DRUG INTERACTIONS. HOWEVER, THERE ARE CERTAIN LIABILITIES ASSOCIATED WITH HISTORICAL ANTIMICROBIAL PEPTIDES AS SYSTEMIC THERAPEUTICS, INCLUDING PROPENSITY FOR LYSIS OF HUMAN CELL MEMBRANES CAUSING TOXICITY AND DEGRADATION BY CIRCULATING PROTEASES AND PEPTIDASES. OUR PRELIMINARY STUDIES HAVE SHOWN THAT: 1) SEVERAL OF THE AIMMAX PEPTIDES HAVE ANTIFUNGAL ACTIVITY ACROSS CANDIDA SPECIES, INCLUDING ACTIVITY AGAINST RESISTANT STRAINS, 2) THIS ACTIVITY IS RAPIDLY FUNGICIDAL IN NATURE, 3) THERE IS NO CELL LYSIS OR INTRACELLULAR CYTOTOXICITY AGAINST HUMAN CELLS AND THEY ARE WELL-TOLERATED FOLLOWING REPEAT DOSING IN VIVO, 4) THEY ARE SALT TOLERANT AND RETAIN ACTIVITY UNDER PHYSIOLOGICAL CONDITIONS, AND 5) THEY CAN BE MODIFIED TO INCREASE STABILITY AGAINST PROTEOLYTIC DEGRADATION AND DEMONSTRATE GOOD PLASMA EXPOSURE IN VIVO. THE OBJECTIVE OF THIS PROPOSAL IS TO OPTIMIZE THE PEPTIDES BY ENHANCING ANTIFUNGAL ACTIVITY AND MICROBIOLOGICAL PROFILE, WHILE MAINTAINING SAFETY (NO TOXICITY) AND MINIMIZING PROTEOLYTIC INSTABILITY AND UNDESIRABLE PHYSICOCHEMICAL PROPERTIES. THESE STUDIES ARE ESSENTIAL TO SELECT POTENT ANTIFUNGAL PEPTIDES TO COMBAT RESISTANCE AND ENSURE THAT THEY ARE “DRUGGABLE” FOR FURTHER DEVELOPMENT. THE OBJECTIVES OF THE PROPOSAL WILL BE ACHIEVED BY RATIONAL PEPTIDE DESIGN AND STRUCTURE-ACTIVITY RELATIONSHIP ANALYSIS USING DATA FROM A SERIES OF IN VITRO AND IN VIVO SCREENING ASSESSMENTS. PEPTIDES SELECTED BASED ON PRE-DETERMINED CRITERIA WILL UNDERGO EXPANDED EVALUATIONS. TOGETHER, THESE STUDIES WILL FORM THE BASIS OF CANDIDATE SELECTION FOR FURTHER DEVELOPMENT AND IND-ENABLING WORK IN A PHASE 2 SBIR APPLICATION. THE ULTIMATE GOAL OF THIS PROGRAM IS TO DEVELOP A BROAD- SPECTRUM ANTIFUNGAL DRUG THAT WILL ADDRESS THE RISING THREAT OF DRUG RESISTANCE IN CANDIDA SPECIES AND PROVIDE AN ALTERNATIVE TREATMENT OPTION FOR LIFE-THREATENING INVASIVE CANDIDIASIS.

HIGHER EDUCATION EMERGENCY RELIEF FUND ASSISTING STUDENTS AFFECTED BY COVID-19.

FY 2024 BEHAVIORAL HEALTH SERVICE EXPANSION - THE WAIMANALO HEALTH CENTER (WHC) IS REQUESTING $600,000 TO SIGNIFICANTLY ENHANCE ITS CAPACITY TO ADDRESS THE NEEDS OF THE UNDERSERVED PATIENT POPULATIONS OF WAIMANALO AND THE KO’OLAUPOKO AREA BY EXPANDING BEHAVIORAL HEALTH SERVICES TO THE COMMUNITY. THE COMMUNITY OF WAIMANALO IS LOCATED ON THE EAST SIDE OF THE ISLAND OF OAHU AND IS NOT ONLY DEFINED BY ITS GEOGRAPHICAL FEATURES BUT ALSO BY THE CHALLENGES AND OPPORTUNITIES THAT ARISE FROM ITS UNIQUE POPULATION. ALTHOUGH WHC SERVES PATIENTS REPRESENTING ALL AREAS OF THE ISLAND, COMMUNITY-BASED EFFORTS FOCUS ON THE LARGE NATIVE HAWAIIAN POPULATION OF WAIMANALO. THIS AREA INCLUDES 7,249 WAIMANALO RESIDENTS WHO ARE NATIVE HAWAIIAN OR PART-HAWAIIAN, APPROXIMATELY 66% OF THE POPULATION OF WAIMANALO. WAIMANALO REPRESENTS ONE OF THE MOST CONCENTRATED AREAS OF HAWAIIANS IN THE STATE. FUNDING WILL SUPPORT THE HIRING OF AN ADDITIONAL BEHAVIORAL HEALTH (BH) PROVIDER, WHO WILL ASSIST WHC’S MOBILE MEDICINE TEAM IN SERVING THOSE WHO ARE HOUSELESS AT SHELTERS, PARKS, CAMPS TO DELIVER BEHAVIORAL HEALTH SERVICES ON-SITE. THE BH PROVIDER WILL ALSO EXPAND BEHAVIORAL HEALTH SERVICES BY ADDING EVENING HOURS ON FOUR WEEKDAYS. WHC’S CURRENT PSYCHIATRY SERVICES ARE AT FULL CAPACITY, AS PATIENTS ARE NEEDING TO WAIT A MONTH OR LONGER FOR A NEW PATIENT APPOINTMENT. WHC PLANS TO HIRE AN ADDITIONAL PSYCHIATRIST FOR 8 HOURS A WEEK TO REDUCE WAIT TIMES AND INCREASE ACCESS, AS THERE ARE LIMITED PSYCHIATRISTS ACCEPTING MEDICARE AND MEDICAID INSURANCE PLANS. THE PSYCHIATRIST WILL ALSO FUNCTION AS A CONSULTANT TO THE INTEGRATED PRIMARY CARE TEAM, THEREBY IMPROVING THE SKILLS IN PRESCRIBING PSYCHIATRIC MEDICATIONS FOR PRIMARY CARE PROVIDERS. FUNDING WILL ALSO SUPPORT THE HIRING OF A BEHAVIORAL HEALTH ADMINISTRATIVE ASSISTANT, WHO WILL ASSIST WITH SCHEDULING BEHAVIORAL HEALTH APPOINTMENTS, COORDINATING WITH PRIMARY CARE TEAM MEMBERS, COLLABORATING WITH INTENSIVE DRUG TREATMENT PROVIDERS AND PSYCHIATRIC HOSPITALS, AND ASSISTING WITH R EFERRALS. WHC WILL ALSO HIRE ANOTHER PRIMARY CARE PROVIDER WHO IS ABLE TO PROVIDE FDA APPROVED MEDICATIONS FOR THE TREATMENT OF ADDICTION, SUCH AS BUPRENORPHINE, NALOXONE AND NALTREXONE. THE ADDITIONAL PRIMARY CARE PROVIDER WILL HELP WITH INCREASING ACCESS TO PRIMARY CARE SERVICES AND BEHAVIORAL HEALTH SERVICES. DURING PRIMARY CARE SERVICES, WHC ROUTINELY SCREENS FOR MENTAL HEALTH AND SUBSTANCE USE DISORDERS AND THERE IS AN AUTOMATIC WARM HAND-OFF TO BEHAVIORAL HEALTH SERVICES FOR POSITIVE SCREENS. WHC WILL ALSO HIRE A CARE MANAGER, WHO WILL ASSIST PATIENTS WITH MENTAL HEALTH AND SUBSTANCE USE DISORDERS BY REDUCING BARRIERS TO CARE. THIS WILL INCLUDE HELPING WITH UNSTABLE HOUSING, FINANCIAL STRAIN, LIMITED ACCESS TO TRANSPORTATION, AND COORDINATING WITH WHC STAFF AND COMMUNITY PROVIDERS TO DEVELOP AN INTEGRATED AND COMPREHENSIVE PLAN OF CARE FOR OUR MOST COMPLEX PATIENTS.

INDIAN COMMUNITY DEVELOPMENT BLOCK GRANT PROGRAM

WASH’EM PROJECT BUILD A PROCESS DESIGNED TO HELP HUMANITARIANS DESIGN RAPID, EVIDENCE-BASED AND CONTEXT-SPECIFIC HYGIENE BEHAVIOUR CHANGE PROGRAMMES.

TRANSPORTATION EQUIPMENT

HEALTH CENTER CORONAVIRUS AID, RELIEF, AND ECONOMIC SECURITY (CARES) ACT FUNDING