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TO PROVIDE EMERGENCY HUMANITARIAN COORDINATION, NUTRITION, HEALTH, PROTECTION AND WASH SERVICES IN SOUTH SUDAN

PROPEL ADAPT SEEKS TO ADDRESS POLICY, ADVOCACY, FINANCING, AND GOVERNANCE CHALLENGES IN FRAGILE SETTINGS THAT CAUSE BARRIERS TO CARE.

THIS ACTION ESTABLISHES A NEW AWARD FOR HEALTH, NUTRITION, PROTECTION, WATER, SANITATION, AND HYGIENE, AND MULTI-PURPOSE CASH ASSISTANCE IN NORTHERN ETHIOPIA.

TO PROVIDE HUMANITARIAN CASH BASED FOOD ASSISTANCE TO VULNERABLE HOUSEHOLDS IN NORTHERN ETHIOPIA.

TO PROVIDE ASSISTANCE IN SOUTH SUDAN THROUGH THE AG/FS, HEALTH, HCIM, HPSA, NUTRITION, PROTECTION, AND WASH.

TO PROVIDE INTEGRATED LIFE-SAVING AND EARLY RECOVERY RESPONSES TO CONFLICT AND NATURAL DISASTER-AFFECTED COMMUNITIES IN ETHIOPIA

APPPROVE NEW IDA FUNDS FOR HAITI/CE

TO PROVIDE FOOD ASSISTANCE, NUTRITION, WASH, AGRICULTURE IN ISIOLO AND MANDERA COUNTIES, KENYA.

BIOMATERIAL MANUFACTURING SUITE IN SUPPORT OF NIH/NIAID AND THE GLOBAL INFECTIOUS DISEASE RESEARCH COMMUNITY - BIOMATERIAL MANUFACTURING SUITE IN SUPPORT OF NIH/NIAID AND THE GLOBAL INFECTIOUS DISEASE RESEARCH COMMUNITY PROJECT DIRECTOR: REBECCA BRADFORD, MBA, MS, PMP® PROJECT SUMMARY THE PROJECT IS TO CONSTRUCT AND COMMISSION A BIOMATERIAL MANUFACTURING SUITE (BMS) AS AN EXPANSION WITHIN THE HIGH CONTAINMENT FACILITY (HCF) CURRENTLY UNDER DESIGN AT THE AMERICAN TYPE CULTURE COLLECTION (ATCC). ATCC IS A NON-PROFIT ENTITY IN MANASSAS, VIRGINIA, SERVING THE FEDERAL GOVERNMENT FOR OVER 50 YEARS THROUGH OUR FEDERAL SOLUTIONS (AFS) DIVISION. THE PROPOSED AIM OF THE BMS IS TO PROVIDE MODERN AND REPRODUCIBLE LARGE-SCALE BIOMATERIAL MANUFACTURING CAPABILITIES FOR PRIORITY PATHOGENS. RESIDING WITHIN THE SOON-TO-BE-BUILT HCF, THE BMS WILL OFFER THE NATIONAL INSTITUTE OF HEALTH AND THE NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES (NIH/NIAID) HIGH-THROUGHPUT AND RAPID DEVELOPMENT PIPELINES FOR BIOMATERIALS OF PUBLIC HEALTH CONCERN, INCLUDING THOSE OF EPIDEMIC OR PANDEMIC POTENTIAL. THE BMS WILL DIRECTLY SUPPORT FEDERAL AGENCIES AND THE INFECTIOUS DISEASE RESEARCH COMMUNITIES BY OPTIMIZING PATHOGENIC ORGANISMS’ GROWTH, PRODUCTION, AND CHARACTERIZATION FOR DOWNSTREAM USE. BY FUNDING THE BMS WITHIN THE PLANNED FACILITY, AFS CAN ENHANCE OUR SUPPORT TO NIH/NIAID THROUGH OUR ABILITY TO OFFER LARGE-SCALE STOCKS OF WELL-CHARACTERIZED CHALLENGE MATERIALS AT NO COST TO THE RESEARCH COMMUNITY THROUGH AFS MANAGED PROGRAMS, INCLUDING BEI RESOURCES. IN TURN, THIS WILL ACCELERATE INFECTIOUS DISEASE RESEARCH FOR VACCINE AND THERAPEUTIC DEVELOPMENT IN OUTBREAK SITUATIONS AND SERVE AS BIOLOGICAL STANDARDS FOR DEVELOPING DETECTION ASSAYS. AFS’ CURRENT MODULAR 7,500 FT2 HCF WAS BUILT IN 2007 AS A TEMPORARY SOLUTION TO FACILITATE THE EXPANDING NEEDS OF AFS’ HEALTH AND HUMAN SERVICES (HHS) PROGRAMS. THE FACILITY IS NOW OVER- EXTENDED WITH RESPECT TO LIFESPAN, CAPACITY, AND CAPABILITIES. AFS DUTIFULLY MAINTAINS THE UPKEEP OF THE CURRENT HCF TO SUPPORT THE EXTENSIVE NIH/NIAID REQUESTS FOR BIOLOGICAL PRODUCTS TO ADVANCE OUR MEDICAL COUNTERMEASURES AND ARSENAL AGAINST VARIANTS FOR THE RECENT ONSLAUGHT OF THE COVID- 19 PANDEMIC. AS A NON-PROFIT ORGANIZATION, ATCC HAS COMMITTED SEVERAL MILLION DOLLARS TO DESIGN AND CONSTRUCT A NEW HCF TO ENHANCE AND MODERNIZE OUR SUPPORT TO NIH. THE EXPLICIT GOAL OF THIS FUNDING IS TO INCLUDE THE DESIGN, CONSTRUCTION, AND COMMISSIONING OF THE BMS WITHIN THE FACILITY FOOTPRINT TO PROVIDE CRITICAL BIOLOGICAL MANUFACTURING CAPABILITIES IN THE BIOMEDICAL SPACE TO ACCELERATE TRANSLATIONAL RESEARCH FOR VACCINE AND THERAPEUTIC DEVELOPMENT.

ATCC'S HIGH CONTAINMENT FACILITY RENOVATIONS IN SUPPORT OF NIAID AND PANDEMIC PREPAREDNESS - PROJECT SUMMARY: THE PROPOSED PROJECT AIMS TO RENOVATE ATCC'S HIGH CONTAINMENT FACILITY (HCF) AT THE AMERICAN TYPE CULTURE COLLECTION (ATCC) IN MANASSAS, VIRGINIA. ATCC'S 7,500 FT2 BIOCONTAINMENT FACILITY WAS BUILT IN 2007 WITH FUNDING FROM NIAID AND HAS BEEN DEDICATED TO DEVELOPING INFECTIOUS DISEASE STRAINS AND REAGENTS NEEDED TO RAPIDLY ADVANCE DIAGNOSTICS, VACCINES, AND THERAPEUTICS AGAINST PRIORITY PATHOGENS. SINCE 2003, ATCC HAS PARTNERED WITH NIAID TO CENTRALIZE AND PROVIDE CRITICAL SCIENTIFIC RESOURCES THROUGH THE BIODEFENSE AND EMERGING INFECTIONS RESOURCES (BEI RESOURCES) PROGRAM. THE NIAID ESTABLISHED BEI RESOURCES TO PROVIDE THE GLOBAL RESEARCH COMMUNITY WITH REAGENTS, TOOLS, AND INFORMATION FOR STUDYING CATEGORY A, B, AND C PRIORITY PATHOGENS, EMERGING INFECTIOUS DISEASE AGENTS, AND OTHER MICROBIOLOGICAL MATERIALS RELEVANT TO HUMAN HEALTH. OVER THE PAST 18 YEARS, ATCC HAS PROVIDED OVER 1,360,000 REAGENTS TO OVER 14,000 INVESTIGATORS AT 3,740 INSTITUTIONS IN 119 COUNTRIES SPANNING OVER 500 HUMAN PATHOGENS IN NIAID'S PRIORITY PORTFOLIO. DURING THIS PERIOD, BEI RESOURCES HAS PROVIDED CRITICAL MATERIALS FOR VITAL DISEASE OUTBREAKS, INCLUDING H1N1, MERS, EBOLA, AND ZIKA. OVER THE PAST TWO YEARS, ATCC HAS RAPIDLY CREATED MORE THAN 690 SARS-COV-2 PRODUCTS; ACQUIRED, PRODUCED, AND AUTHENTICATED MORE THAN 165 STOCKS OF SARS-COV-2 FOR BOTH GENERAL RESEARCH AND CHALLENGE STUDIES; AND SHIPPED MORE THAN 86,000 RESEARCH REAGENTS TO OVER 2,800 RESEARCHERS IN MORE THAN 70 COUNTRIES FOR THE DEVELOPMENT OF COUNTERMEASURES AND BASIC RESEARCH. THE MATERIAL PROVIDED BY BEI RESOURCES HAS BEEN CITED IN MORE THAN 1,800 SARS-COV-2 PUBLICATIONS SINCE FEBRUARY OF 2020. IN ADDITION, ATCC HAS FOSTERED COLLABORATION AND PARTNERSHIPS ACROSS NIAID PROGRAMS AND EXTERNAL WORKING GROUPS TO SHARE RESOURCES, INFORMATION, AND DATA TO ACCELERATE DISCOVERIES AND HARMONIZE SCIENTIFIC APPROACHES FOR PANDEMIC RESPONSE AND PREPAREDNESS. ATCC'S HIGH CONTAINMENT FACILITY HOUSES LABORATORIES ESSENTIAL FOR BSL-3 AND SELECT AGENT INFECTIOUS DISEASE RESEARCH, PRODUCT DEVELOPMENT, AND LARGE-SCALE REAGENT PRODUCTION FOR THE RESEARCH COMMUNITY. THIS PROPOSAL AIMS TO RENOVATE AND UPGRADE THE HVAC, DECONTAMINATION, AND SECURITY SYSTEMS. THE RENOVATIONS ALSO INCLUDE UPGRADES TO FIXED EQUIPMENT AND INTERIOR FINISHING IN THE FACILITY. THE RENOVATIONS WILL MODERNIZE THE FACILITY FOR USE BY 40 PH.D. ATCC SCIENTISTS, COLLABORATORS, AND LABORATORY SUPPORT STAFF. THE PRODUCTS AND SERVICES DEVELOPED IN THE FACILITY WILL SUPPORT THOUSANDS OF SCIENTISTS GLOBALLY EACH YEAR TO PREPARE AND RESPOND TO PANDEMICS. ATCC IS SEEKING THIS OPPORTUNITY FOR ENGAGEMENT WITH THE NIAID TO INVEST IN THIS FACILITY WHICH HAS BEEN FOUNDATIONAL FOR THE NATION'S PANDEMIC RESPONSE AND PREPAREDNESS.

TO MAXIMIZE THE POTENTIAL THAT HUMANITARIAN CASH AND VOUCHER ASSISTANCE CAN BRING TO CRISIS CONTEXTS

USAID FOREIGN ASSISTANCE FOR PROGRAMS OVERSEAS

THE PROJECT AIMS TO PREVENT NUTRITION RELATED MORTALITY AND MORBIDITY AMONG IDPS AND RETURNEES IN SOMALI AND OROMIYA REGIONS, THROUGH QUALITY EMERGENCY RESPONSE.

EMERGENCY FOOD SECURITY PROGRAM

HUMANITARIAN ASSISTANCE

THIS IS A NEW 24-MONTH AWARD FOR "PROMOTING BETTER NUTRITION OUTCOMES WITH TECHNICAL SUPPORT FOR DATA, PREPAREDNESS, RESPONSE, AND RECOVERY" IN WORLDWIDE.

NEIGHBORHOOD STABILIZATION PRG

TO CONTRIBUTE TO THE REDUCTION OF THE RISK OF MORBIDITY AND MORTALITY AMONG SOUTH SUDANESE REFUGEE AND HOST COMMUNITY POPULATION IN THE GAMBELLA REGION, ETHIOPIA.

AN ASSISTANCE AWARD TO SUPPORT HUMANITARIAN STAFF, IN PARTICULAR NATIONAL STAFF AND WOMEN, TO IMPROVE THEIR SKILLS AND COMPETENCIES TO ASSUME LEADERSHIP AND DECISION-MAKING ROLES; AND THUS, ADVANCE THE LOCALIZATION AGENDA.

BUILDING KNOWLEDGE, CAPACITY AND SKILLS IN CASH TRANSFER PROGRAMMING IN THE UNITED STATES HUMANITARIAN SECTOR

TO CONTRIBUTE TO THE REDUCTION OF THE RISK OF MORBIDITY AND MORTALITY AMONG SOUTH SUDANESE REFUGEES AND HOST COMMUNITY POPULATION IN THE GAMBELLA REGION, ETHIOPIA

TO ALLEVIATE THE EFFECTS OF DROUGHT, SAVE LIVES, PREVENT THE DEPLETION OF HOUSEHOLD ASSETS AND LIVELIHOODS, AND ACCELERATE THE RECOVERY OF VULNERABLE COMMUNITIES THROUGH IMPLEMENTATION OF LIFE-SAVING INTERVENTIONS INWASH, NUTRITION, AGRICULTURE, AND FOOD ASSISTANCE IN BARINGO COUNTY IN KENYA.

TO CONTRIBUTE TO THE REDUCTION OF THE RISK OF MORBIDITY AND MORTALITY AMONG SOUTH SUDANESE REFUGEE AND HOST COMMUNITY POPULATIONS IN THE GAMBELLA.

ENTITLED CITIES

ENTITLED CITIES

FOSTER CHANGES TO INCREASE THE SCALE AND QUALITY OF CVA, BY ENABLING INFORMATION SHARING AND COLLABORATION, INCREASING ACCESS TO AND USE OF EVIDENCE, AND STRENGTHENING THE SKILLS AND KNOWLEDGE OF HUMANITARIAN PRACTITIONERS.

IMPROVED HEALTH AND NUTRITION STATUS AMONG SOUTH SUDANESE REFUGEES IN UGANDA.

INTEGRATED WASH, NUTRITION AND AGRIC & FOOD SECURITY FOR VULNERABLE COMMUNITIES IN KENYA

EMERGENCY ASSISTANCE TO VULNERABLE POPULATIONS IN NIGER

TO ENHANCE ACCOUNTABILITY OF HUMANITARIAN NUTRITION ORGANIZATIONS TOWARDS GBV AND GENDER EQUALITY.

HUMANITARIAN ASSISTANCE

TO ENHANCE ACCOUNTABILITY OF HUMANITARIAN NUTRITION ORGANIZATIONS TOWARDS GENDER BASED VIOLENCE (GBV) AND GENDER EQUALITY.

NEW 12 MONTH AWARD TO IMPROVE NUTRITION INFORMATION SYSTEMS (NIS)

HUMANITARIAN ASSISTANCE

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AGRICULTURAL RESEARCH SERVICE - AMERICAN TYPE CULTURE COLLECTION BIOLOGICAL REPOSITORY PARTNERSHIP - THE NATIONAL BIO- AND AGRO-DEFENSE FACILITY (NBAF) WILL BE THE PREMIER CENTER OF SCIENTIFIC EXCELLENCE FOR THE STUDY OF TRANSBOUNDARY, EMERGING AND ZOONOTIC ANIMAL DISEASES IN THE UNITED STATES. RESEARCH CONDUCTED AT THE PLUM ISLAND DISEASE CENTER (PIADC) WILL TRANSITION TO NBAF ALONG WITH THE PIADC BIOLOGICAL COLLECTION. THIS COLLABORATIVE AGREEMENT BETWEEN ARS AND AMERICAN TYPE CULTURE COLLECTION (ATCC) WILL ESTABLISH A REMOTE REPOSITORY FOR BIOLOGICAL MATERIAL SUPPORTING THE ARS-NBAF IN PARTNERSHIP. THE MATERIAL WILL BE EXPANDED, PRESERVED AND WHEN APPROPRIATE, DISTRIBUTED BACK TO ARS OR OTHER ENTITIES.

CITIES RECOVERY

THE COOPERATOR WILL, USING ITS INDEPENDENT JUDGMENT AND EXPERTISE, SUPPORT THE PROJECT THROUGH A MIXED METHODS EVALUATION IMPLEMENTED THROUGH A FOUR-PHASED APPROACH: EVALUATION DESIGN; TOOL DEVELOPMENT; DATA COLLECTION; AND DATA ANALYSIS, REPORTING, AND INTEGRATION OF FINDINGS. THE COOPERATOR WILL ASSESS ANY CHANGES IN THE CAPACITIES OF GRANTEES TO ADDRESS COMMUNITY NEEDS RELATED TO DIGITAL INCLUSION, COMMUNITY MEMORY, OR TRANSFORMING SCHOOL LIBRARY PRACTICE. THIS PROJECT IS INTENDED TO HELP THE LIBRARY AND ARCHIVE FIELDS, THE PUBLIC, IMLS, AND OTHER STAKEHOLDERS BETTER UNDERSTAND THE EFFICACY OF VARIOUS METHODS THAT CAN BUILD THE CAPACITY OF LIBRARIES AND ARCHIVES TO ADDRESS SPECIFIC ISSUES IMPORTANT TO THEIR COMMUNITIES. PRIMARY AUDIENCES FOR THIS PROJECT ARE THE APP MENTOR ORGANIZATIONS, THE APP GRANTEES, THE BROADER LIBRARY AND ARCHIVES PROFESSIONS, THE PUBLIC, AND IMLS

STTR PHASE I: TRANSFER TRAINING DEVICE TO REDUCE FALLS AND INCREASE MOBILITY IN OLDER ADULTS -THE BROADER IMPACT/COMMERCIAL POTENTIAL OF THIS SMALL BUSINESS TECHNOLOGY TRANSFER (STTR) PHASE I PROJECT IS A NOVEL WALKER WITH ACTIVE CORRECTIVE FEEDBACK AND TRAINING PROTOCOLS ENABLING PATIENTS THE ABILITY TO RELIABLY AND REPEATEDLY TRANSITION FROM A SEATED POSITION TO A STANDING POSTURE. FALLS AMONG ELDERLY ADULTS ARE THE LEADING CAUSE OF INJURY RESULTING IN 3 MILLION EMERGENCY ROOM VISITS AND 800,000 HOSPITALIZATIONS. THESE ACCIDENTS ACCOUNT FOR $50 BILLION IN DIRECT MEDICAL COSTS EACH YEAR. THIS PROJECT AIMS TO DEVELOP A NOVEL DEVICE WHICH DIRECTLY IMPROVES THE SIT-TO-STAND (STS) TRANSFER PHASE WHICH ACCOUNTS FOR 41% OF FALLS IN ELDERLY AND/OR COGNITIVELY IMPAIRED ADULTS. OVER HALF OF INDIVIDUALS USING WALKERS CURRENTLY DO NOT RECEIVE THE PROPER ASSISTIVE-DEVICE UTILIZATION TRAINING DUE TO VARYING THERAPIST TECHNIQUES, COMMUNICATION, ENVIRONMENT, OR THE PATIENT'S COGNITIVE ABILITIES. THIS SMALL BUSINESS TECHNOLOGY TRANSFER (STTR) PHASE I PROJECT AIMS TO DEVELOP A DEVICE FOR ENSURING A SAFER AND MORE CONSISTENT TRANSITION FROM A SIT-TO-STAND POSTURE IN PATIENTS USING FRONT-WHEEL WALKERS. CURRENT SIT-TO-STAND TRAINING RELIES SOLELY UPON VERBAL THERAPIST INSTRUCTION OR DEMONSTRATION AND OFTEN RESULTS IN LACK OF CONSISTENCY IN DELIVERY. THE PROPOSED DEVICE INTEGRATES BIOMECHANICAL MEASUREMENTS, TRAINED THERAPIST OBSERVATIONS, AND PATIENT AUDITORY AND VISUAL FEEDBACK, IN CONJUNCTION WITH AN EDUCATIONAL AND TRAINING PROTOCOL, TO ENSURE PROPER PATIENT BIOMECHANICS, IN A SEMI-AUTONOMOUS MANNER. A PROTOTYPE SYSTEM WILL BE DEVELOPED AND VALIDATED IN A PATIENT PROOF OF CONCEPT STUDY DEMONSTRATING CONSISTENT AND RELIABLE POSTURE CHANGES IN ORDER TO SIGNIFICANTLY REDUCE THE RISKS FOR FALLS AND INJURIES, WHILE REDUCING EMOTIONAL AND PHYSICAL DEMANDS ON PATIENTS AND CAREGIVERS. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

THE COOPERATOR WILL, USING ITS INDEPENDENT JUDGMENT AND EXPERTISE, SUPPORT THE PROJECT THROUGH A MIXED METHODS EVALUATION IMPLEMENTED THROUGH A FOUR-PHASED APPROACH: EVALUATION DESIGN; TOOL DEVELOPMENT; DATA COLLECTION; AND DATA ANALYSIS, REPORTING, AND INTEGRATION OF FINDINGS. THE COOPERATOR WILL ASSESS ANY CHANGES IN THE CAPACITIES OF GRANTEES TO ADDRESS COMMUNITY NEEDS RELATED TO DIGITAL INCLUSION, COMMUNITY MEMORY, OR TRANSFORMING SCHOOL LIBRARY PRACTICE. THIS PROJECT IS INTENDED TO HELP THE LIBRARY AND ARCHIVE FIELDS, THE PUBLIC, IMLS, AND OTHER STAKEHOLDERS BETTER UNDERSTAND THE EFFICACY OF VARIOUS METHODS THAT CAN BUILD THE CAPACITY OF LIBRARIES AND ARCHIVES TO ADDRESS SPECIFIC ISSUES IMPORTANT TO THEIR COMMUNITIES. PRIMARY AUDIENCES FOR THIS PROJECT ARE THE APP MENTOR ORGANIZATIONS, THE APP GRANTEES, THE BROADER LIBRARY AND ARCHIVES PROFESSIONS, THE PUBLIC, AND IMLS

GENOME-WIDE MAPPING (GWM) OF HOST PROTEOME: PAN ALPHAVIRUS PROTEOME INTERACTIONS FOR DISCOVERY OF BROAD-SPECTRUM COUNTERMEASURES

VALUE- ADDED AGRICULTURAL PRODUCT MARKET DEVELOPMENT GRANTS

WASTE DISPOSAL GRANTS - REGULAR

HOST-BASED ANTI-MICROBIAL PEPTIDES (AMP) AS THERAPEUTIC STRATEGIES FOR ALPHAVIRUS INFECTIONS

RURAL COOPERATIVE DEVELOPMENT INITIATIVE GRANTS

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NUTRIACTION+ STRENGTHENING LOCALLY LED EMERGENCY NUTRITION RESPONSE FOR HUMANITARIAN AND PUBLIC HEALTH EMERGENCIES

REDUCING HEALTH RISK EXPOSURES FROM FLOODING IN MUNCIE INDIANA

INITIAL FUNDING FOR START-UP