University Of Richmond

CARES ACT: EMERGENCY FINANCIAL AID GRANTS TO STUDENTS

UR CARES: EMERGENCY RELIEF - INSTITUTIONAL ALLOCATION

DISABILITY AND REHABILITATION RESEARCH PROGRAM: VR-ROI PROJECT: ESTIMATING RETURN ON INVESTMENT IN STATE VOCATIONAL REHABILITATION PROGRAMS

NATIONAL CENTER FOR EDUCATION RESEARCH

TAS::89 0222::TAS NUCLEAR AND PARTICLE PHYSICS RESEARCH

CAREER: SELECTION PIPELINE FOR ANCIENT AND MODERN GENOMES: IMPROVING ACCESS TO GENOMIC METHODS FOR STUDYING HUMAN ADAPTATIONS -AS MODERN HUMANS DISPERSED INTO NEW ENVIRONMENTS AROUND THE GLOBE, DIRECTIONAL SELECTION PLAYED AN IMPORTANT ROLE IN SHAPING THE GENETIC VARIANTS PRESENT ACROSS DIFFERENT POPULATIONS. MANY DIVERSE AND UNIQUE ADAPTATIONS EXIST, OFTEN PLAYING A LARGE ROLE IN HUMAN HEALTH AND CULTURE. TOOLS THAT CAPTURE GENOMIC PATTERNS OF SELECTION ARE INSTRUMENTAL FOR DETERMINING HOW DIRECTIONAL SELECTION HAS IMPACTED MODERN HUMAN POPULATIONS, AND RAPID ADVANCES IN SEQUENCING TECHNOLOGY HAVE GREATLY EXPANDED THE NUMBER OF ANCIENT AND PRESENT-DAY HUMAN GENOMES FOR STUDY. HOWEVER, THE NUMBER OF RESEARCHERS WITH THE BIOINFORMATIC EXPERTISE NEEDED TO USE THESE TOOLS IS LIMITED, AND REFINED DEMOGRAPHIC MODELS TO BETTER INFORM SELECTION INFERENCES ARE NOT WIDELY AVAILABLE FOR DIFFERENT HUMAN POPULATIONS. THIS PROJECT WILL DEVELOP SOFTWARE INFRASTRUCTURE FOR STUDYING ADAPTATIONS IN MODERN HUMANS USING ANCIENT AND PRESENT-DAY GENOMIC DATASETS THAT CAN BE IMPLEMENTED BY RESEARCHERS WITH LOW COMPUTATIONAL EXPERTISE. THIS PROJECT WILL IMPLEMENT THE PIPELINE IN COURSE-BASED UNDERGRADUATE RESEARCH EXPERIENCES (CURES) TO ACCELERATE DETECTION AND CHARACTERIZATION OF POSITIVE SELECTION IN GENOMIC REGIONS OF INTEREST FOR WORLDWIDE HUMAN POPULATIONS. IN ADDITION, THIS PROJECT WILL PROVIDE APPLIED COMPUTING TRAINING TO UNDERGRADUATE STUDENTS AND PROFESSIONAL DEVELOPMENT RELATED TO THE SELECTION SOFTWARE FOR HIGHER EDUCATION BIOLOGY FACULTY, WHICH WILL HELP MORE STUDENTS ACROSS THE NATION GAIN GENOMICS-BASED RESEARCH SKILLS. IN TOTAL, THIS PROJECT WILL SUPPORT FUTURE RESEARCHERS BY TRAINING ONE POSTDOCTORAL FELLOW, TWO POST-BACCALAUREATE STUDENTS, AND TEN UNDERGRADUATE RESEARCH STUDENTS, AS WELL AS APPROXIMATELY 60 UNDERGRADUATE STUDENTS AND 30 HIGHER EDUCATION BIOLOGY FACULTY IN RELATED DATA SCIENCE SHORT COURSES AND GENOMICS WORKSHOPS. THIS PROJECT WILL DEVELOP SOFTWARE INFRASTRUCTURE ESTABLISHING A FLEXIBLE, MODULARIZED, AND ACCESSIBLE SELECTION PIPELINE INCORPORATING ANCIENT AND PRESENT-DAY HUMAN GENOMIC DATASETS THAT CAN BE IMPLEMENTED BY RESEARCHERS WITH LIMITED COMPUTATIONAL BACKGROUND. A RELIABLE DEMOGRAPHIC MODEL FOR EAST AND SOUTHEAST ASIANS WILL BE CREATED AND INCORPORATED INTO THIS PIPELINE, AND THIS TOOL WILL BE USED TO CHARACTERIZE SELECTION AT PUTATIVELY ADAPTED GENES IN EAST AND SOUTHEAST ASIANS, WHICH WILL BE BENEFICIAL TO FURTHER RESEARCH ON HUMAN HEALTH AND EVOLUTIONARY HISTORY. TO FACILITATE DATA SCIENCE AND RESEARCH SKILLS ACROSS THE FUTURE STEM WORKFORCE, THIS RESEARCH WILL BE INTEGRATED WITH EDUCATION IN THE FOLLOWING WAYS. FIRST, UNDERGRADUATE STUDENTS WILL CONDUCT ORIGINAL RESEARCH PROJECTS USING THE SELECTION PIPELINE THROUGH INDEPENDENT SUMMER RESEARCH OR AN UPPER-LEVEL BIOLOGY COURSE. SECOND, THIS PROJECT WILL CREATE WORKSHOPS FOR HIGHER EDUCATION FACULTY FOCUSED ON THE CURRICULUM AND IMPLEMENTATION OF THE SELECTION PIPELINE AS A CURE, EXTENDING THIS OPPORTUNITY TO MORE UNDERGRADUATES ACROSS THE NATION. THIRD, THIS PROJECT WILL DEVELOP A ONE-WEEK APPLIED COMPUTING SHORT COURSE FOR UNIVERSITY OF RICHMOND SUMMER RESEARCH STUDENTS THAT WILL PROVIDE COMPUTING TRAINING TO THE FUTURE STEM WORKFORCE. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

COLLABORATIVE RESEARCH: LEVEL II PREPARING UNDERGRADUATES FOR RESEARCH IN STEM-RELATED FIELDS USING ELECTROPHYSIOLOGY (PURSUE)

THE AMAZON RAINFOREST PROVIDES ECOSYSTEM SERVICES TO 33 MILLION PEOPLE INCLUDING 1.5 MILLION INDIGENOUS PEOPLE FROM 385 DIFFERENT GROUPS LIVING WITHIN THE BIOME BOUNDARY. HERE WE BUILD OFF THE OUTCOMES OF TWO WORKSHOPS IN THE CENTRAL .....

NEW; A THEORETICAL INVESTIGATION OF THE STRUCTURE AND REACTIVITY OF THE MOLECULAR CONSTITUENTS OF OIL SAND AND OIL SHALE; PI: CAROL A. PARISH

FIELD INITIATED

MRI: ACQUISITION OF APPARATUS TO STUDY THE "EXPRESSION" OF THE PARENTAL BRAIN

HOW BRIGHT IS THE RADIO SKY? A 310 MHZ ABSOLUTE MAP -IT IS IMPORTANT TO OBSERVE ALL OF THE LIGHT THAT COMES TO US FROM ASTRONOMICAL SOURCES IN THE UNIVERSE, INCLUDING THE KINDS OF LIGHT THAT HUMAN EYES CANNOT SEE, LIKE THE LONGER WAVELENGTH OF LIGHT CALLED RADIO WAVES.? IN ADDITION TO THE RADIO WAVES THAT COME FROM BRIGHT OBJECTS IN SPACE THAT WE KNOW ABOUT, THERE IS ALSO DIFFUSE RADIO EMISSION WHICH COMES FROM EVERY DIRECTION IN THE SKY.? THIS DIFFUSE RADIO EMISSION CAN ONLY BE PROPERLY UNDERSTOOD BY OBSERVING IT OVER LARGE PORTIONS OF THE SKY AT DIFFERENT RADIO WAVELENGTHS.? THIS PROJECT WILL MAKE A NEW, MODERN MAP OF THESE SIGNALS BY UTILIZING THE UNIQUE FEATURES OF THE ROBERT C. BYRD GREEN BANK TELESCOPE ALONG WITH ADVANCED CUSTOM INSTRUMENTATION DEVELOPED SPECIFICALLY FOR THIS PROJECT.? THE INVESTIGATORS WILL LEVERAGE CUTTING-EDGE RADIO RECEIVER TECHNOLOGY AND CONTEMPORARY COMPUTING CAPABILITIES TO ACHIEVE UNPRECEDENTED ACCURACY.? THE RESULTING PICTURE OF THE RADIO EMISSION COMING FROM OUR UNIVERSE WILL BE AVAILABLE TO THE ASTRONOMICAL COMMUNITY AS AN IMPORTANT RESOURCE. THIS PROJECT WILL ALSO PROVIDE ESSENTIAL DIRECT TRAINING OPPORTUNITIES FOR RESEARCHERS AND STUDENTS. ? THIS PROJECT WILL PRODUCE A NEW MAP OF THE ABSOLUTE SKY BRIGHTNESS AT 310 MHZ, WITH ANGULAR RESOLUTION FINER THAN GALACTIC FEATURES AS WELL AS POLARIZATION INFORMATION. THE RESULTING MAP WILL BE THE FIRST SUCH LARGE-SCALE, ABSOLUTELY CALIBRATED RADIO MAP TO BE MADE IN 40 YEARS AND THE ONLY ONE EVER WHERE AN ABSOLUTE ZERO-LEVEL CALIBRATION IS THE PRIMARY GOAL.? THIS MAP OF THE WHOLE SKY NORTH OF -47 DEGREES DECLINATION, WITH ALL GALACTIC LATITUDES OBSERVED, WILL ALLOW A DETERMINATION, FOR THE FIRST TIME IN A SYSTEMATICALLY RELIABLE WAY, OF THE ABSOLUTE LEVEL OF DIFFUSE RADIO EMISSION IN THE UNIVERSE AND FROM GALACTIC STRUCTURE.? IT WILL PROVIDE AN IMPORTANT NEW RESOURCE FOR UNDERSTANDING AND CONSTRAINING ALMOST ALL GALACTIC AND EXTRAGALACTIC PHENOMENA THAT MANIFEST IN, OR DEPEND ON THE UNDERSTANDING OF, DIFFUSE RADIO EMISSION. THESE INCLUDE COSMIC MICROWAVE BACKGROUND STUDIES, 21-CM COSMOLOGY, COSMIC RAY PROPAGATION, MAGNETIC FIELD STRUCTURES, SUPERNOVA REMNANT AND PULSAR SEARCHES, COMPOSITION OF THE INTERSTELLAR MEDIUM, FINER SCALE RADIO STRUCTURE, TRACERS FOR GALACTIC PHENOMENA AT OTHER WAVELENGTHS, INVESTIGATIONS OF THE RADIO SYNCHROTRON BACKGROUND, AND MANY MORE.? THE INVESTIGATORS WILL DEPLOY A CUSTOM, NOVEL POLARIZATION-SENSITIVE RECEIVER AND LOW SIDELOBE, HIGH EDGE-TAPER FEED ON THE GREEN BANK TELESCOPE.? THE NOVEL RECEIVER TECHNOLOGIES THAT WILL BE DEPLOYED AND CHARACTERIZED HAVE THE POTENTIAL TO YIELD IMPORTANT APPLICATIONS IN RADIO ASTRONOMY.? THIS PROJECT WILL PROVIDE ESSENTIAL DIRECT TRAINING FOR POSTDOCTORAL RESEARCHERS AND UNDERGRADUATE STUDENTS, AS WELL AS MANY POTENTIAL RESEARCH OPPORTUNITIES FOR GRADUATE STUDENTS GIVEN THE WIDE VARIETY OF ASTROPHYSICAL INVESTIGATIONS IT WILL ENABLE. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

CAREER: THEORETICAL STUDIES OF THE RELATIONSHIPS BETWEEN BONDING PREFERENCES IN INORGANIC MOLECULES, THEIR OLIGOMERS, AND EXTENDED SOLIDS - FOCUSING

NA-121.1 "NUCLEAR STEWARDSHIP RESEARCH"

LIPID MODULATION OF POTASSIUM CHANNELS

THE SYNTHESIS AND BIOLOGICAL EVALUATION OF PYRROLE CONTAINING MARINE NATURAL PROD

CAREER: STUDY AND DESIGN OF MODULAR AMINOPHOSPHINE LIGANDS FOR CROSS-COUPLING REACTIONS

NUCLEAR STEWARD RESEARCH AT THE UNIVERSITY OF RICHMOND

CAREER: MACROMOLECULAR RECOGNITION AND DIFFERENTIAL ION CHANNEL FUNCTIONING

BRC-BIO: MECHANISTIC INSIGHTS INTO AMPA RECEPTOR TRAFFICKING DURING LONG-TERM POTENTIATION -THIS PROJECT WILL EXPLORE MOLECULES INVOLVED IN MEMORY FORMATION, A PROCESS THAT RELIES ON PRECISELY ORCHESTRATED COMMUNICATION BETWEEN NEURONS. SPECIFICALLY, THIS WORK WILL FOCUS ON HOW NEURONS POPULATE THEIR MEMBRANES WITH RECEPTORS, KNOWN AS ?AMPA? RECEPTORS, THAT CAN RESPOND TO NEUROTRANSMITTERS. THIS PROCESS REQUIRES INTRACELLULAR MEMBRANE VESICLES TO FUSE WITH THE PLASMA MEMBRANE OF NEURONS. THOUGH MEMBRANE FUSION HAS BEEN STUDIED FOR DECADES, THE REGULATION OF MEMBRANE FUSION IN AMPA RECEPTOR (AMPAR) DELIVERY IS STILL POORLY UNDERSTOOD. THIS PROJECT WILL DESCRIBE KEY STEPS IN THE DELIVERY PROCESS AND AIMS TO IDENTIFY NOVEL PROTEINS INVOLVED IN RECEPTOR TRAFFICKING DURING LEARNING AND MEMORY. TOGETHER, THESE AIMS WILL ADVANCE THE UNDERSTANDING OF HOW MEMORIES FORM. THIS WORK WILL BE PERFORMED PRIMARILY BY UNDERGRADUATES, BOTH IN MENTORED RESEARCH PROJECTS AND IN A COURSE-BASED UNDERGRADUATE RESEARCH EXPERIENCE (CURE). THESE EFFORTS WILL SIGNIFICANTLY EXPAND THE TRAINING OPPORTUNITIES AVAILABLE TO UNDERGRADUATE STUDENTS. AT THE NEURONAL SYNAPSE, MEMBRANE FUSION IS NOT ONLY ESSENTIAL FOR THE DELIVERY OF NEUROTRANSMITTER MOLECULES BUT ALSO FOR THE INSERTION OF NEUROTRANSMITTER RECEPTORS INTO THE PLASMA MEMBRANE. THOUGH MEMBRANE FUSION INVOLVED IN THE DELIVERY OF NEUROTRANSMITTERS IS WELL-CHARACTERIZED, COMPARATIVELY LITTLE IS KNOWN ABOUT THE REGULATION OF NEUROTRANSMITTER RECEPTOR DELIVERY. MEMBRANE FUSION DURING AMPAR INSERTION INTO THE PLASMA MEMBRANE IS DRIVEN BY SNARE PROTEINS, INCLUDING SYNTAXIN-3, SYNAPTOBREVIN-2, AND SNAP-47 (S47). THIS PROJECT WILL INVESTIGATE THE ROLE OF S47, SPECIFICALLY FOCUSING ON ITS POORLY CHARACTERIZED N-TERMINAL AND LINKER DOMAINS. AN IN VITRO FUSION ASSAY WILL BE USED TO DESCRIBE THE FUNCTION OF THE UNCHARACTERIZED S47 DOMAINS, AND SINGLE-PARTICLE CRYO-ELECTRON MICROSCOPY (CRYOEM) WILL BE USED TO SOLVE THE STRUCTURE OF THE SNARE PROTEIN COMPLEX INVOLVED IN AMPAR EXOCYTOSIS. THESE DATA WILL PROVIDE INSIGHT INTO THE REGULATION OF MEMBRANE FUSION DURING AMPAR DELIVERY TO THE PLASMA MEMBRANE. ADDITIONALLY, AN ALPHAFOLD MULTIMER SCREEN OF POSTSYNAPTIC PROTEINS WILL BE COMBINED WITH IN VITRO VALIDATION OF PROTEIN-PROTEIN INTERACTIONS TO IDENTIFY NEW PROTEIN REGULATORS OF AMPAR TRAFFICKING. COMBINED, THESE AIMS WILL ADVANCE OUR UNDERSTANDING OF THE REGULATION OF SYNAPTIC PLASTICITY AND MEMORY FORMATION. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

MYOSIN-XIX AND THE MOLECULAR MECHANISM OF ACTIN-BASED MITOCHONDRIAL ORGANIZATION

CLAAI : CENTER FOR LIBERAL ARTS AND AI [CLAAI WILL BRING TOGETHER RESEARCHERS, STUDENTS, AND PEDAGOGY EXPERTS WORKING WITHIN SMALL LIBERAL ARTS COLLEGES TO STUDY THE SOCIAL, CULTURAL, AND LEGAL POSSIBILITIES AND CHALLENGES OF AI. WE WILL (1) DEVELOP COLLABORATIVE RESEARCH THROUGH RESEARCH FELLOWSHIPS, (2) EXPAND COURSE OFFERINGS ON THE ETHICAL ISSUES THAT ARISE WITHIN AI AND WAYS WE CAN USE AI TO ADDRESS PRESSING SOCIAL ISSUES THROUGH COURSE TRANSFORMATION AND PROFESSIONAL DEVELOPMENT GRANTS, AND (3) EXPAND ACCESS TO AI METHODS THROUGH IN-PERSON AND DIGITAL WORKSHOPS AND TALKS, AND (4) SUPPORT KNOWLEDGE SHARING AND CREATION WITHIN AND BEYOND RICHMOND BY BUILDING ON UR?S STRENGTH IN VISUAL AI. WITH UR AS THE CENTRAL NODE, CLAAI WILL BE A NETWORKED COLLABORATION WITH THE ASSOCIATED COLLEGES OF THE SOUTH (ACS), A CONSORTIUM OF 16 SMALL LIBERAL ARTS COLLEGES IN THE SOUTHERN UNITED STATES INCLUDING HISTORICALLY BLACK COLLEGES, RELIGIOUSLY-AFFILIATED INSTITUTIONS, AND NONSECTARIAN-PRIVATE INSTITUTIONS FROM TEXAS TO VIRGINIA.]

NA-121.1 NUCLEAR STEWARDSHIP RESEARCH

RUI: UNDERSTANDING STEROID REGULATION OF IONOTROPIC GLUTAMATE RECEPTORS

IDENTIFYING AND CHARACTERIZING HEME TOLERANCE GENES IN THE TSETSE SYMBIONT SODALIS GLOSSINIDIUS

DECONSTRUCTING DEPRESSOGENIC SUSCEPTIBILITY AND EMOTIONAL RESILIENCE IN RATS

STEWARDSHIP SCIENCE AT THE UNIVERSITY OF RICHMOND

INVESTIGATION OF BLOOD FITNESS GENES IN THE TSETSE FLY SYMBIONT SODALIS GLOSSINIDIUS - PROJECT SUMMARY/ABSTRACT: TSETSE FLIES (GENUS: GLOSSINA) ARE CYCLIC VECTORS OF PROTOZOAN AFRICAN TRYPANOSOMES (TRYPANOSOMA SP.), THE CAUSATIVE AGENTS OF HUMAN AND ANIMAL AFRICAN TRYPANOSOMIASES, WHICH IMPART A SIGNIFICANT HEALTH AND SOCIOECONOMIC BURDEN IN SUB-SAHARAN AFRICA. WHILE ONLY A SMALL PERCENTAGE OF TSETSE ARE INFECTED WITH TRYPANOSOMES, THEY ALL HOUSE A MIXED POPULATION OF INDIGENOUS ENDOSYMBIOTIC BACTERIA, INCLUDING SODALIS GLOSSINIDIUS. S. GLOSSINIDIUS RESIDES IN TSETSE’S MIDGUT, WHICH IS EXPOSED TO LARGE AMOUNTS OF IMBIBED BLOOD. THE CENTRAL HYPOTHESIS UNDERLYING THE WORK PROPOSED IN THIS APPLICATION IS THAT S. GLOSSINIDIUS COLONIZATION OF THE TSETSE GUT REQUIRES EXPRESSION OF A SUITE OF GENES THAT ENABLES THE BACTERIUM TO ACCESS NUTRIENTS FROM AND SURVIVE WITHIN THIS BLOOD-RICH ENVIRONMENT. THE SCIENTIFIC GOALS OF THIS PROJECT ARE TO EXAMINE THESE HYPOTHESES. IN SPECIFIC AIM 1, S. GLOSSINIDIUS TRANSPOSON LIBRARIES WILL BE SCREENED FOR CANDIDATE GENES THAT CONTRIBUTE TO FITNESS IN BLOOD. IN SPECIFIC AIM 2, CLEAN MUTATIONS IN THE CANDIDATE BLOOD FITNESS GENES WILL BE GENERATED AND THE MUTANTS WILL BE CHARACTERIZED FOR IN VITRO GROWTH AND SURVIVAL PHENOTYPES IN BLOOD COMPONENTS. IN SPECIFIC AIM 3, THE S. GLOSSINIDIUS STRAINS WITH NULL MUTATIONS IN BLOOD FITNESS GENES WILL BE TESTED FOR THEIR ABILITY TO COLONIZE THE TSETSE FLIES. BECAUSE A POSITIVE CORRELATION EXISTS BETWEEN THE DENSITY OF S. GLOSSINIDIUS AND THE PREVALENCE OF TRYPANOSOME INFECTION IN TSETSE’S MIDGUT, A MORE COMPLETE UNDERSTANDING OF THE SODALIS-TSETSE SYMBIOSIS WILL HAVE SIGNIFICANT

UNIVERSITY COORDINATED COMMUNITY RESPONSE: THE CAMPUS ALLIANCE TO END VIOLENCE

TRACKING ADAPTIVE EVOLUTION IN REAL TIME IN AN INVASIVE FRUIT FLY - PROJECT SUMMARY INVASIVE SPECIES, WHICH CAN CARRY DISEASES, DECIMATE FOOD CROPS AND THREATEN BIODIVERSITY, ARE IMMENSELY SUCCESSFUL IN NEW ENVIRONMENTS, BUT THE BIOLOGICAL MECHANISMS THAT ENABLE THEIR SPREAD REMAIN ELUSIVE. SOME INVASIVE SPECIES SHOW SIGNS OF RAPID ADAPTATION TO NEW HABITATS, BUT FEW STUDIES HAVE CAPTURED POST-INVASION ADAPTATION IN REAL TIME. ADDITIONALLY, INVASIVE SPECIES COLONIZING MULTIPLE HABITATS SIMULTANEOUSLY OFFER THE OPPORTUNITY TO STUDY THE LONGSTANDING QUESTION OF WHETHER EVOLUTION IS PREDICTABLE. TO UNDERSTAND HOW QUICKLY AND PREDICTABLY ORGANISMS ADAPT TO NEWLY COLONIZED ENVIRONMENTS, DETAILED GENOMIC STUDIES OF REPEATED INCIPIENT INVASIONS ARE NECESSARY. IN THIS STUDY, WE WILL GENETICALLY AND PHENOTYPICALLY CHARACTERIZE NORTH AMERICAN POPULATIONS OF THE AFRICAN FIG FLY, ZAPRIONUS INDIANUS, TO TEST FOR LOCAL ADAPTATION AND PARALLEL EVOLUTION IN ITS ONGOING INVASION. THIS TRACTABLE MODEL ORGANISM ARRIVED IN NORTH AMERICA LESS THAN TWO DECADES AGO AND RAPIDLY SPREAD. OUR DATA SUGGEST IT IS LOCALLY EXTIRPATED FROM TEMPERATE HABITATS EACH WINTER AND RE-COLONIZES THESE LOCALES EACH SPRING. OUR CENTRAL HYPOTHESIS IS THAT Z. INDIANUS UNDERGOES PREDICTABLE POST-COLONIZATION ADAPTATION ACROSS MULTIPLE LOCATIONS AND YEARS, RESULTING IN REPEATED CHANGES IN ALLELE FREQUENCIES AND ECOLOGICALLY RELEVANT PHENOTYPES. TO TEST THIS HYPOTHESIS, WE WILL COLLECT, SEQUENCE, AND PHENOTYPE ISOLATES FROM ALONG THE EAST COAST OF NORTH AMERICA AND FROM TWO FOCAL VIRGINIA ORCHARDS OVER MULTIPLE YEARS. IN AIM 1, WE WILL QUANTIFY GENETIC AND PHENOTYPIC VARIATION IN NORTH AMERICAN POPULATIONS BY GENERATING POOLED SEQUENCING OF POPULATIONS COLLECTED ALONG A LATITUDINAL GRADIENT TO TEST FOR CLINALLY VARYING POLYMORPHISMS OVER TWO SAMPLING YEARS. WE WILL ALSO PHENOTYPE LINES COLLECTED AT DIFFERENT LATITUDES TO TEST FOR CLINAL DIFFERENCES IN MORPHOLOGICAL, LIFE-HISTORY, AND STRESS TOLERANCE PHENOTYPES. REPEATED CLINAL AND PHENOTYPIC DIFFERENTIATION WOULD PRESENT EVIDENCE FOR RAPID ADAPTATION TO LOCAL ENVIRONMENTS. IN AIM 2, WE WILL SAMPLE AND SEQUENCE FLIES FROM TWO GEOGRAPHICALLY SEPARATE VIRGINIA ORCHARDS OVER THREE GROWING SEASONS TO TEST FOR ALLELES AND PHENOTYPES THAT PREDICTABLY CHANGE FOLLOWING INVASION. THESE EXPERIMENTS WILL ALLOW US TO IDENTIFY THE GENOMIC TARGETS OF POST-INVASION ADAPTATION AND QUANTIFY THE PREDICTABILITY OF EVOLUTION. IN AIM 3, WE WILL CHARACTERIZE THE PUTATIVE TARGET OF A RECENT SELECTIVE SWEEP IN NORTH AMERICAN FLIES: A 600 KB HAPLOTYPE THAT IS COMMON IN VIRGINIA, INTERMEDIATE FREQUENCY IN FLORIDA, AND NOT FOUND IN AFRICA. WE WILL GENERATE OUTBRED POPULATIONS FIXED FOR ALTERNATE ALLELES AND PERFORM RNASEQ TO TEST FOR DIFFERENTIAL GENE EXPRESSION ASSOCIATED WITH ALTERNATE HAPLOTYPES. PHENOTYPING EXPERIMENTS WILL EXPLORE THE POTENTIAL FUNCTIONAL TARGETS OF THIS SWEEP, ALLOWING US TO DISSECT THE BIOLOGICAL FUNCTION OF A GENOMIC SIGNAL OF SELECTION. COLLECTIVELY, THESE EXPERIMENTS WILL TAKE A MULTIPRONGED APPROACH TO TEST FOR POST-INVASION ADAPTATION AND PARALLEL EVOLUTION IN REAL TIME. THIS STUDY WILL PROVIDE A FRAMEWORK TO UNDERSTANDING RAPID ADAPTATION TO NOVEL ENVIRONMENTS AND PREDICTING EVOLUTIONARY TRAJECTORIES OF FUTURE INVASIVE SPECIES, WHICH MAY LEAD TO SOLUTIONS TO CONTROL THEIR SPREAD.

RUI-ARTS. DECIPHERING THE HIDDEN DIVERSITY OF THE NEOTROPICAL FROG GENUS ELACHISTOCLEIS (ANURA, MICROHYLIDAE)

RUI: ELUCIDATING THE SIGNALING INTERACTIONS THAT CONTROL SPINAL CORD FATE SPECIFICATION

RUI: THEORETICAL STUDIES OF NON-COVALENT INTERACTIONS AND CHEMICAL BONDING TRANSITIONS ACROSS PHASES IN INORGANIC SYSTEMS, AND INVESTIGATIONS OF OTHER MODES OF WEAK BONDING

RUI: TOWARDS A BETTER UNDERSTANDING OF POLYRADICAL ELECTRONIC STRUCTURE: HARNESSING ORGANIC BUILDING BLOCKS FOR THE DESIGN OF MOLECULAR MAGNETS -IN THIS RUI PROJECT, FUNDED BY THE CHEMICAL MECHANISM, FUNCTION, AND PROPERTIES PROGRAM OF THE CHEMISTRY DIVISION, PROFESSOR CAROL PARISH OF THE DEPARTMENT OF CHEMISTRY AT THE UNIVERSITY OF RICHMOND WILL DEVELOP MODELS TO BETTER UNDERSTAND THE FUNDAMENTAL BEHAVIOR OF NON-METALLIC MOLECULE-BASED MAGNETS. MAGNETIC MATERIALS ARE CRITICALLY IMPORTANT IN THE DEVELOPMENT AND MANUFACTURE OF DEVICES FOR NAVIGATION, IMAGING, SENSING, RECORDING AND GEOLOCATION. MAGNETS ARE WIDELY USED IN APPLICATIONS RANGING FROM ELECTRIC MOTORS, TO HARD DRIVE DATA STORAGE, TO SOUND AND VIDEO RECORDING, TO MEDICAL IMAGING. THE MOST COMMON MAGNETS IN USE TODAY ARE METAL ALLOYS THAT EXTEND ACROSS LARGE, EXTENDED LATTICES. THESE CONVENTIONAL MAGNETS ARE RIGID, BULKY AND HEAVY. MAGNETS FORMED FROM ORGANIC MATERIALS ARE EXTREMELY FLEXIBLE, MALLEABLE AND LIGHTWEIGHT; HOWEVER, THEY ARE LESS WELL UNDERSTOOD. THIS PROJECT WILL HARNESS PROFESSOR PARISH?S EXPERTISE IN THE PROPER CHARACTERIZATION OF MOLECULES WITH UNPAIRED ELECTRONS TO DESIGN BETTER MATERIALS FOR MAGNETIC APPLICATIONS. THE RESEARCH WILL ADDRESS THREE MAJOR QUESTIONS IN MATERIALS SCIENCE: (1) HOW DO REMARKABLE PROPERTIES OF MATTER EMERGE FROM COMPLEX RELATIONSHIPS AT THE ATOMIC, MAGNETIC, AND ELECTRONIC LEVEL? (2) HOW DO WE CONTROL MATERIAL PROCESSES AT THE LEVEL OF ELECTRONS? (3) HOW DO WE DESIGN REVOLUTIONARY NEW FORMS OF MATTER WITH TAILORED PROPERTIES? THE PROJECT IS HIGHLY INTERDISCIPLINARY, UTILIZING CONCEPTS FROM PHYSICAL, MATERIALS AND ORGANIC CHEMISTRY, AND WILL PROVIDE AN IDEAL ENVIRONMENT IN WHICH TO EDUCATE AND TRAIN THE NEXT GENERATION OF SCIENTISTS. THE PROJECT TEAM WILL USE HIGHLY CORRELATED, MULTIREFERENCE METHODS TO CHARACTERIZE THE GROUND AND EXCITED STATES OF A VARIETY OF DI AND POLYRADICAL MOLECULES THAT SERVE AS MODELS FOR THE DEVELOPMENT OF MOLECULAR MAGNETS. PROFESSOR PARISH AND HER RESEARCH GROUP WILL CHARACTERIZE THE ELECTRONIC STRUCTURE AND MAGNETIC PROPERTIES OF THESE POLYRADICALS, AND USE THIS DATA, ALONG WITH MAGNETIC PROPERTIES OBTAINED FROM EXPERIMENTAL MEASUREMENTS, TO DEVELOP A PREDICTIVE MODEL FOR MOLECULAR MAGNETISM IN ORGANIC POLYRADICALS. THE RESULTS FROM THESE STUDIES WILL PROVIDE FUNDAMENTAL INFORMATION TO SUPPORT THE DESIGN OF ORGANIC MAGNETS THAT WILL BE MORE FLEXIBLE AND LIGHTER THAN CONVENTIONAL METAL-BASED MAGNETS WITH A SMALLER, LESS TOXIC ENVIRONMENTAL FOOTPRINT. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

RUI: THE ROLE OF PROTEIN DYNAMICS IN CATALYSIS AND SUBUNIT COOPERATIVITY

BRC-BIO: LOOKING BEYOND THE CALORIE: NUTRITIONAL ECOLOGY IN A GENERALIST PREDATOR -CALORIES ARE OFTEN TREATED AS THE PRIMARY UNIT OF NUTRITION, BUT A GROWING BODY OF EVIDENCE SUGGESTS THAT THE SPECIFIC NUTRIENT COMPOSITION OF FOOD MAY BE A MORE IMPORTANT DRIVER OF FORAGING BEHAVIOR IN WILDLIFE. BECAUSE NUTRIENT COMPOSITION VARIES WITH ENVIRONMENTAL CONDITIONS, CLIMATE CHANGE IS LIKELY TO AFFECT NUTRIENT CONTENT OF FOOD. FOR PREDATORS, THIS MEANS THAT A CHANGING CLIMATE COULD ALTER THE NUTRITION OF THEIR PREY, AND THEREFORE, WHAT PREY THEY SELECT. HOWEVER, WITHOUT BASELINE KNOWLEDGE OF HOW NUTRIENTS SHIFT IN RESPONSE TO CHANGING ENVIRONMENTAL CONDITIONS, IT IS DIFFICULT TO MAKE PREDICTIONS ABOUT PREDATOR BEHAVIOR. SONGBIRDS ARE COMMON PREDATORS IN MANY ECOSYSTEMS THAT PREY ON A VARIETY OF INSECTS AND CAN EASILY BE CAPTURED AND OBSERVED FOR BEHAVIORAL STUDIES. THIS PROJECT WILL 1) ASSESS MACRONUTRIENTS (PROTEIN, CARBOHYDRATE, LIPID) IN PREY AND IDENTIFY SPECIFIC RATIOS OF MACRONUTRIENTS THAT MAXIMIZE NESTLING GROWTH, 2) EXAMINE HOW THE NUTRITIONAL VALUE OF PREY CHANGES WHEN REARED IN EXPERIMENTALLY MANIPULATED ENVIRONMENTAL CONDITIONS, AND 3) EXAMINE WHETHER CHANGES IN NUTRITION AFFECT BIRDS? PREFERENCE FOR PREY. BECAUSE INSECTS ARE CONSUMED BY MANY ANIMALS OUTSIDE OF BIRDS, THIS WORK WILL HAVE CONSERVATION IMPLICATIONS FOR A WIDE RANGE OF TAXA. THE RESEARCH TEAM WILL INCLUDE UNDERGRADUATE STUDENTS ENROLLED IN RELEVANT BIOLOGY COURSES AND PAID UNDERGRADUATE ASSISTANTS. STUDENTS WILL DEVELOP INDEPENDENT PROJECTS RELATED TO THE BROADER THEME AND TRAVEL TO NATIONAL CONFERENCES TO PRESENT THEIR WORK. THIS RESEARCH EXPERIENCE WILL EQUIP PARTICIPANTS WITH SKILLS IN LABORATORY AND FIELD WORK AND BUILD STUDENTS? CONFIDENCE TO PERSIST IN STEM CAREERS. USING A COMBINATION OF MANIPULATIVE LABORATORY EXPERIMENTS AND AN EXISTING NETWORK OF 100 EASTERN BLUEBIRD NEST-BOXES, THE RESEARCHERS WILL EXAMINE HOW ENVIRONMENTAL CONDITIONS AFFECT PREY NUTRIENT COMPOSITION AND WHETHER THESE CHANGES IMPACT PREDATOR PREFERENCE. THIS WORK WILL TEST THE USE OF THE NUTRITIONAL GEOMETRIC FRAMEWORK: A TOOL FOR ASSESSING NUTRITION BY UTILIZING RATIOS OF NUTRIENTS TO MODEL HOW FOODS ARE COMBINED TO REACH MULTIDIMENSIONAL NUTRITIONAL TARGETS THAT MAXIMIZE ORGANISM PERFORMANCE. THIS FRAMEWORK IS USEFUL IN MODELING HOW DIET CHANGES AS DIFFERENT FOOD ITEMS CHANGE IN AVAILABILITY OR QUALITY. BY MEASURING THE IMPACT OF PREY MACRONUTRIENTS ON NESTLING DEVELOPMENT IN OBJECTIVE 1, THE RESEARCHERS WILL IDENTIFY MULTIDIMENSIONAL NUTRITIONAL TARGETS THAT MAXIMIZE GROWTH IN NESTLINGS. IN OBJECTIVE 2, THESE DATA WILL BE USED TO TEST WHETHER THE ENVIRONMENTAL CONDITIONS OF PREY MEANINGFULLY IMPACT THEIR NUTRIENT CONTENT. ALTHOUGH SOME STUDIES INVESTIGATE HOW NUTRIENTS CHANGE IN RESPONSE TO TEMPERATURE OR DIET SHIFTS, VERY FEW EXAMINE THESE IN COMBINATION, EVEN THOUGH CLIMATE CHANGE IS PREDICTED TO SIMULTANEOUSLY AFFECT BOTH. EXPERIMENTS IN OBJECTIVE 2 MANIPULATING DIET AND REARING TEMPERATURE WILL ADVANCE OUR UNDERSTANDING OF HOW MULTIPLE ENVIRONMENTAL CHANGES INTERACT TO DETERMINE NUTRITIONAL VALUE. FINALLY IN OBJECTIVE 3, RESEARCHERS WILL EXAMINE BLUEBIRD NUTRITIONAL PREFERENCES USING FIELD-BASED CHOICE ASSAYS WITH NUTRITIONALLY ALTERED INSECT PREY. THE EXPERIMENTS IN THIS PROJECT WILL ADVANCE BASIC SCIENCE OF NUTRITIONAL ECOLOGY BY EXAMINING HYPOTHESES FROM THE NUTRITIONAL GEOMETRIC FRAMEWORK AND LIFE HISTORY THEORY, THE OUTCOMES OF WHICH WILL INFORM CONSERVATION APPLICATIONS. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

ENZYMATIC AND MOTOR PROPERTIES OF MYOSIN 19

SODALIS GLOSSINIDIUS IRON ACQUISITION

NUCLEAR STRUCTURE RESEARCH AT RICHMOND

INVESTIGATING THE REGULATION OF DED1 IN TRANSLATION AND RNA STORAGE

PGVIS: DIGITAL PUBLIC HUMANITIES SOFTWARE FOR VISUALIZING IMAGE COLLECTIONS [THE PHOTOGRAMMAR VISUALIZATION SOFTWARE (PGVIS) IS AN OPEN-SOURCE TOOL FOR THE VISUALIZATION AND EXPLORATION OF IMAGE COLLECTIONS. PGVIS WILL ALLOW ANYONE WITH A COLLECTION OF DIGITAL IMAGES AND ASSOCIATED METADATA TO CREATE, WITH NO PRIOR PROGRAMMING EXPERIENCE, THEIR OWN DIGITAL PUBLIC HUMANITIES PROJECTS IN THE FORM OF PUBLIC WEBSITES. IN ADDITION TO THE SOFTWARE, THE PROJECT WILL PRODUCE SIX CASE STUDIES THAT WILL MODEL AND HIGHLIGHT HOW THE SOFTWARE CAN BE USED IN A VARIETY OF DIFFERENT DOMAINS, DATA SIZES, AND TYPES OF INSTITUTIONS.]

NUCLEAR STRUCTURE RESEARCH AT RICHMOND

RUI: COMPUTATIONAL DEVELOPMENTAL BILINGUALISM: A SELF-ORGANIZING MODEL OF BILINGUAL LEXICAL ACQUISITION

DEVELOPMENT OF NON-TOXIC CARBON DOTS AS BONE-SPECIFIC CARRIER FOR DRUG DELIVERY

TESTING THE THERAPEUTIC POTENTIAL OF CARBON NANODOTS IN BONE MINERALIZATION DISEASES

RUI: ARTS. REVISION OF THE POORLY KNOWN FROG GENUS CHIASMOCLEIS (ANURA, MICROHYLIDAE)

STEWARDSHIP SCIENCE AT THE UNIVERSITY OF RICHMOND

RUI: CHARACTERIZING PYROLYSIS AND COMBUSTION PATHWAYS FOR ASPHALTENE MODEL COMPOUNDS

MRI-R2: ACQUISITION OF A COMPUTER CLUSTER FOR UNDERGRADUATE RESEARCH AND TEACHING IN COMPUTATIONAL CHEMISTRY

COLLABORATIVE RESEARCH: ATOL: PORTOL - THE PORIFERA TREE OF LIFE PROJECT

RUI: A THEORETICAL INVESTIGATION OF MULTIREFERENCE DIRADICAL MOLECULES

RUI: COLLABORATIVE RESEARCH: MULTIREFERENCE STUDIES OF ORGANIC POLYRADICALS, RADICAL REACTIONS AND GRAPHENE NANORIBBONS

RUI: EXPLORING HALOGEN BONDING AS A FUNDAMENTAL INTERACTION TOWARD THE DEVELOPMENT OF NANOPARTICLE-BASED SCREENING METHODS FOR EXPLOSIVE MOLECULE DETECTION

RUI: CHEMICAL INVESTIGATIONS INTO THE BIOACTIVITY OF THE DNA LESION 8-OXO-2'-DEOXYGUANOSINE

RUI: XEROGEL-BASED AMPEROMETRIC BIOSENSORS INCORPORATING NANOPARTICLE NETWORKS - ADAPTABLE TEMPLATES FOR CLINICALLY RELEVANT MEASUREMENTS

RUI: CHEMICAL INVESTIGATIONS INTO THE BIOACTIVITY OF THE DNA LESION 8-OXO-2'-DEOXYGUANOSINE

RUI: NANOPARTICLE FILM ASSEMBLIES: INTERFACES FOR CONTROLLING THE NANOSCALE ADSORPTION ENVIRONMENT AND ELECTROCHEMICAL BEHAVIOR OF IMMOBILIZED REDOX

NUCLEAR AND PARTICLE PHYSICS RESEARCH

NUCLEAR STEWARDSHIP RESEARCH

IBSS-EX: SBP: RUI: AN INTERDISCIPLINARY APPROACH FOR INCREASING FEMALE INVOLVEMENT AND ACHIEVEMENT IN STEM

HIGH PERFORMANCE COMPUTER FOR BIOMEDICAL RESEARCH - PROJECT SUMMARY THE UNIVERSITY OF RICHMOND (UR) IS A RESEARCH-INTENSIVE PREDOMINANTLY UNDERGRADUATE INSTITUTION (PUI). OUR FACULTY ARE COMMITTED TO PRODUCING CUTTING-EDGE RESEARCH WHILE ALSO PROVIDING PROFESSIONALLY MEANINGFUL TRAINING TO OUR STUDENTS. UNUSUAL FOR A PUI, WE CURRENTLY HAVE FIVE NIH-FUNDED PIS (MAJOR USERS) WORKING ON A VARIETY OF IMPORTANT BIOMEDICAL PROJECTS. THESE FACULTY, TOGETHER WITH SIX OTHER FACULTY (MINOR USERS), HAVE LEADING RESEARCH PROGRAMS IN NEUROSCIENCE, GENOMICS, CANCER, OSTEOPOROSIS, QUANTITATIVE BIOLOGY AND COMPUTATIONAL CHEMISTRY. THESE PROGRAMS DEPEND ON ACCESS TO COMPUTE CYCLES, BUT UR DOES NOT CURRENTLY HAVE AN INSTITUTIONALLY SUPPORTED COMPUTE RESOURCE. OUR FACULTY HAVE BEEN SUPPORTING THEIR WORK USING LAPTOPS, DESKTOPS, BORROWING COMPUTE CYCLES FROM COLLABORATORS, USING CLOUD RESOURCES AND SUPERCOMPUTER CENTERS. AS THE IMPORTANCE OF COMPUTING IN BIOMEDICAL RESEARCH INCREASES, THIS DEFICIENCY IS LIMITING THE SIZE AND NATURE OF THE PROJECTS THAT OUR FACULTY CAN ENVISION AND COMPLETE, PREVENTING THEM FROM ACHIEVING THEIR FULL POTENTIAL OR ENGAGING STUDENTS AS DEEPLY AS THEY COULD. THE ADDITION OF A NINE-NODE, HIGH-PERFORMANCE, SHARED COMPUTATIONAL RESOURCE CONTAINING CPUS, GPUS, LARGE AMOUNTS OF RAM, AND RAID-PROTECTED STORAGE WILL ENABLE OUR FACULTY AND THEIR STUDENTS TO PERFORM STATE-OF-THE-ART COMPUTATIONS. THIS HARDWARE WILL BE USED TO PERFORM GENOMIC ANALYSIS OF TICK-BORNE DISEASES, AND TO STUDY THE EVOLUTION OF HUMAN DEMOGRAPHICS AND POPULATIONS. THE HARDWARE WILL ALSO SUPPORT IMAGE AND/OR VIDEO ANALYSIS RELATED TO AN RNA HELICASE IMPORTANT IN TRANSLATION, A CARBON NANODOT DRUG DELIVERY SYSTEM, AND THE DEVELOPMENT OF A RODENT BASED BEHAVIORAL MODEL OF EFFORT-BASED REWARDS. THE RESOURCE WILL ALSO BE USED FOR MOLECULAR DYNAMICS SIMULATIONS THAT WILL UNRAVEL THE STRUCTURE-FUNCTION RELATIONSHIP IN VOLTAGE AND NON-VOLTAGE GATED POTASSIUM ION CHANNELS, RNA HELICASE, PROTEINS THAT MEDIATE CANCER PROGRESSION, THE BINDING AFFINITY OF CARBON NANODOTS WITH MINERALIZED BONES, AND AMYLOID PRECURSOR PROTEIN WITH A MOTOR PROTEIN, AND THE DESIGN OF A NOVEL DNA POLYMERASE. ACCESS TO THE REQUESTED RESOURCE WILL ALLOW OUR FACULTY AND STUDENTS TO SPEND LESS TIME WAITING FOR NUMERICAL RESULTS AND MORE TIME FORMULATING IMPORTANT NEW QUESTIONS AND GENERATING ACCURATE ANSWERS. THE INNOVATIVE RESEARCH WILL HAVE A DIRECT IMPACT ON HUMAN HEALTH.

RUI: CHEMICAL INVESTIGATIONS INTO THE BIOACTIVITY OF THE DNA LESION 8-OXO-2'-DEOXYGUANOSINE

COLLABORATIVE PROPOSAL: PREPARING UNDERGRADUATES FOR RESEARCH IN STEM-RELATED FIELDS USING ELECTROPHYSIOLOGY (PURSUE)

THE PURPOSE OF THIS AGREEMENT IS TO IMPROVE AN ARTIFICIAL DIET-BASED REARING SYSTEM FOR EMERALD ASH BORER (EAB) AND THE PARASITOIDS BEING RELEASED TO CONTROL IT. THIS PROJECT SUPPORTS EFFORTS TO REAR AND RELEASE BIOLOGICAL CONTROL AGENTS TO SLOW THE SPREAD AND RATE OF DAMAGE CAUSED BY EAB. HUNDREDS OF THOUSANDS OF PARASITOID WASPS ARE REARED UNDER LABORATORY CONDITIONS AT THE EAB BIOCONTROL REARING FACILITY IN BRIGHTON, MI AND DISTRIBUTED TO INFESTED AREAS FOR RELEASE. CURRENT REARING EFFORTS REQUIRE LIVE WOOD AND FOLIAGE TO MAINTAIN EAB REARING, WHICH IS DIFFICULT AND COSTLY. RELEASE OF BIOCONTROL AGENTS IS KEY TO THE RESTORATION OF ASH TREES AND MAINTENANCE OF FOREST ECOSYSTEMS ACROSS A LARGE PORTION OF THE UNITED STATES. STUDIES CONDUCTED FOR THIS AGREEMENT AIM TO INCREASE NEONATE TO LATE INSTAR LARVAL SURVIVAL ON EXTRUDED DIET, DEVELOP METHODS FOR EAB ADULT REARING ON DIET AND SUCCESSFUL PARASITISM OF DIET-REARED EAB LARVAE. ACTIVITIES TO BE PERFORMED: THE RECIPIENT WILL PROVIDE THREE TECHNICIANS (TWO FULL-TIME AND ONE PART-TIME). ONE FULL-TIME AND ONE PART-TIME TECHNICIAN WILL BE BASED AT THE APHIS EAB BIOCONTROL REARING FACILITY IN BRIGHTON, MI. ACTIVITIES WILL INCLUDE CONDUCTING RESEARCH EXAMINING EXTRUDED ARTIFICIAL DIET AND DEVELOPING EAB ADULT REARING METHODS AND DEVELOPING METHODS TO INCREASE PARASITISM RATES OF DIET-REARED EAB. THE OTHER FULL-TIME TECHNICIAN WILL BE STATIONED AT THE FOREST PEST METHODS LABORATORY. THEY WILL RUN THE EXTRUDER AND PRODUCE EXTRUDED DIETS FOR TESTING IN BRIGHTON. THE PRINCIPAL INVESTIGATOR WILL, IN COOPERATION WITH THE APHIS PROJECT MANAGER, PROVIDE A DETAILED PROJECT WORK PLAN, SUPERVISE THE TECHNICIANS, PURCHASE SUPPLIES, AND WRITE REPORTS. THE TECHNICIANS, PROJECT MANAGER, AND RECIPIENT WILL HAVE WEEKLY VIRTUAL MEETINGS TO DISCUSS PROGRESS AND FUTURE PLANNING THROUGHOUT THE PROJECT. DELIVERABLES AND EXPECTED OUTCOMES: A TWIN-SCREW EXTRUDED DIET REARING METHOD TO PRODUCE ADULT EAB AND A TESTABLE PROTOCOL TO DETERMINE WHETHER DIET-REARED EAB CAN BE INCORPORATED INTO THE MASS-REARING PROCEDURES. A METHOD TO INCREASE PARASITISM RATES AND REDUCE LABOR TIME SPENT ON MAKING PARASITOID EXPOSURES. METHODS THAT INCREASE THE NUMBER OF THIRD AND FOURTH INSTARS PRODUCED FOR PARASITOID EXPOSURES. INTENDED BENEFICIARY(IES): EFFORTS WILL BENEFIT U.S. STATE AND GOVERNMENT AGENCIES WHO RELY ON ASH FORESTS, FOREST HEALTH AND ASH TREES IN URBAN LANDSCAPES, TRIBAL COMMUNITIES WHO UTILIZE ASH TREE MATERIALS IN TRADITIONAL CRAFTS, AS WELL AS THE U.S. PUBLIC WHO VISIT FORESTS CONTAINING ASH TREES AND/OR WHO OWN ASH TREES.

COLLABORATIVE RESEARCH: AN INTERDISCIPLINARY APPROACH TO UNDERSTAND SELFISH PARENTAL CARE OF EGG AND LARVAE IN MIXED-SPECIES COMMUNAL NEST BREEDING FRESHWATER FISHES

THE PRIMARY PURPOSE OF THIS AGREEMENT IS TO DEVELOP AND IMPRVE AN ARTIFICIAL-DIET-BASED REARING SYSTEM FOR IMMATURE STAGES OF THE EMERALD ASH BORER (EAB) AND ITS BIOLOGICAL CONTROL AGENTS.

RETRAINING AUTOMATIC BIASES RELATED TO PROBLEM DRINKING IN COLLEGE STUDENTS

RUI: PREPARING FOR THE ERA OF COSMIC MICROWAVE BACKGROUND POLARIMETRY

FINDING POLYGLUTAMINE DISEASE AND RESCUE MECHANISMS USING PROTEOMIC ANALYSIS.

COLLABORATIVE RESEARCH: RUI: EVALUATING THE MOLECULAR GENETIC PATHWAYS RESPONSIBLE FOR STABLE HOST: SYMBIONT INTERACTIONS IN SPONGE:ALGAL ASSOCIATIO

RUI: REACTION ACCELERATION, MEDIATION, AND CATALYSIS BY IN SITU SILYLATION

COLLABORATIVE RESEARCH: RUI: LINKING THERMAL TOLERANCE TO INVASION DYNAMICS: CLIMATE AND PHYSIOLOGICAL CAPACITY AS REGULATORS OF GEOGRAPHICAL SPREAD

COLLABORATIVE RESEARCH: RUI: DYNAMIC LEARNING IN COMPARATIVE COURTS: A CROSS-NATIONAL ANALYSIS OF JUDICIAL DECISION MAKING IN CANADA, THE UNITED STATES, AND THE UNITED KINGDOM

THE PURPOSE OF THIS AGREEMENT IS TO DEVELOP MOLECULAR DIAGNOSTIC TOOLS AND INVESTIGATE POPULATION GENETICS OF INVASIVE PEST INSECTS AND THEIR BIOCONTROL AGENTS, WHICH ARE DETAILED INTO FIVE SECTIONS. THIS AGREEMENT INVOLVES (1) CONDUCTING ANNUAL SPONGY MOTH SURVEY AND EVALUATE BATCH-PROCESSING STRATEGIES, (2) DETERMINATION OF LOSS OF FLIGHT IN HYBRID PROGENIES BETWEEN AGM AND EGM, (3) DEVELOPMENT OF A QPCR ASSAY FOR DETECTING EGG PARASITOIDS OF SPOTTED LANTERNFLY, (4) CONDUCT ANNUAL SURVEY OF OVAVESICULA POPILLIAE IN JAPANESE BEETLE SAMPLES, AND (5) ADDITIONAL SUPPORT FOR MOLECULAR IDENTIFICATION OF FOREST AND AGRICULTURAL PESTS. SPONGY MOTH, JAPANESE BEETLE AND SPOTTED LANTERNFLY ARE INVASIVE PESTS THAT CAUSE SIGNIFICANT ECONOMIC AND ECOLOGICAL DAMAGE TO AGRICULTURE AND NATURAL RESOURCES. THE STAKEHOLDERS FOR THIS WORK ARE BROAD. THERE ARE NO SUBAGREEMENTS.

MRI: ACQUISITION OF A COMPUTING CLUSTER FOR ASTROPHYSICS AND NUCLEAR PHYSICS RESEARCH AT THE UNIVERSITY OF RICHMOND

UNDERGRADUATE INTERNATIONAL STUDIES AND FOREIGN LANGUAGE

RUI: SINGLE MOLECULE METROLOGY IN SCANNING PROBE MICROSCOPY THROUGH CORRECTION OF FAST TIME SCALE POSITIONAL ERRORS

THE PURPOSE OF THIS AGREEMENT IS TO SAFEGUARD U.S. NURSERY PRODUCTION THROUGH THE DEVELOPMENT OF PEST MANAGEMENT TOOLS THAT WILL MINIMIZE THE INCIDENCE, SEVERITY, AND SPREAD OF BOX TREE MOTH (BTM) ON BOXWOOD PLANTS. THIS AGREEMENT FOCUSES ON DEVELOPING A METHOD TO MASS REAR BTM ON LOW-COST ARTIFICIAL DIET THAT DOES NOT REQUIRE LARGE NUMBERS OF EXPENSIVE BOXWOOD PLANTS, AND TO PROVIDE LARGE NUMBERS OF BTM LIFE STAGES FOR RESEARCH ON CONTROL OR ERADICATION OF THE PEST. THIS AGREEMENT WILL ALSO SUPPORT EFFORTS TO SCREEN PESTICIDES AGAINST THE PEST. IN ADDITION, THIS AGREEMENT WILL SUPPORT REARING OF ASIAN LONGHORNED BEETLE (ALB) AND CAPS LURE PRODUCTION.

COLLABORATIVE RESEARCH: IMPLEMENTING MULTI-INSTITUTIONAL CLASSROOM-BASED UNDERGRADUATE RESEARCH EXPERIENCES TO STUDY THE IMPACT OF ENVIRONMENTAL CHANGES ON SALAMANDER POPULATIONS

UBM-GROUP: STUDYING CELL RESPONSE TO INPUT SIGNALS AS THE BASIS FOR INTERDISCIPLINARY TRAINING FOR UNDERGRADUATES IN BIOLOGICAL AND MATHEMATICAL SCIE

THE PRIMARY PURPOSE OF THIS AGREEMENT IS TO IMPROVE AN ARTIFICIAL DIET-BASED REARING SYSTEM FOR EMERALD ASH BORER (EAB) AND THE PARA SITOIDS BEING RELEASED TO CONTROL IT. THIS PROJECT SUPPORTS EFFORTS TO REAR AND RELEASE BIOLOGICAL CONTROL AGENTS TO SLOW THE SPREAD AND RATE OF DAMAGE CAUSED BY EAB. HUNDREDS OF THOUSANDS OF PARASITOID WASPS ARE REARED UNDER LABORATORY CONDITIONS AT THE EAB BIOCO NTROL REARING FACILITY IN BRIGHTON, MI AND DISTRIBUTED TO INFESTED AREAS FOR RELEASE. CURRENT REARING EFFORTS REQUIRE LIVE WOOD AND FOLIAGE TO MAINTAIN EAB REARING, WHICH IS DIFFICULT AND COSTLY. RELEASE OF BIOCONTROL AGENTS IS KEY TO THE RESTORATION OF ASH TREES AND MAINTENANCE OF FOREST ECOSYSTEMS ACROSS A LARGE PORTION OF THE UNITED STATES. STUDIES CONDUCTED FOR THIS AGREEMENT AIM TO INCREASE NEONATE TO LATE INSTAR LARVAL SURVIVAL ON EXTRUDED DIET, DEVELOPMENT OF METHODS FOR LARGE-SCALE PRODUCTION OF EAB LARVAE, AND SUCCESSFUL PARASITISM OF DIET-REARED EAB LARVAE. THE RECIPIENT WILL PROVIDE TWO TECHNICIANS (ONE FULL-TIME AND ONE PART-TIME) WHO WILL BE BASED AT THE APHIS EAB BIOCONTROL REARING FACILITY IN BRIGHTON, MI. ACTIVITIES WILL INCLUDE CONDUCTING RESEARCH EXAMINING VARIOUS ARTIFICIAL DIETS AND DIET PRESENTATION METHODS. TESTING EXTRUDED DIETS THAT WILL BE PRODUCED AT THE FPML AND SHIPPED TO BRIGHTON FOR TESTING. DESIGNING, BUILDING AND TESTING PROTOTYPE PARASITOID CAGES TO PROMOTE EGG LAYING ON EAB LARVAE IN ARTIFICIAL DIET. THE PRINCIPAL INVESTIGATOR WILL, IN COOPERATION WITH THE APHIS PROJECT MANAGER, PROVIDE A DETAILED PROJECT WORK PLAN, SUPERVISE THE TECHNICIANS, PURCHASE SUPPLIES, AND WRITE REPORTS. THE TECHNICIANS, PROJECT MANAGER, AND RECIPIENT WILL HAVE WEEKLY VIRTUAL MEETINGS TO DISCUSS PROGRESS AND FUTURE PLANNING THROUGHOUT THE PROJECT. DELIVERABLES AND EXPECTED OUTCOMES WILL BE PROGRESS TOWARDS A DIET PRESE NTATION AND NEONATE INFESTATION METHOD THAT CAN BE USED IN MASS-REARING, A METHOD TO INCREASE THE NUMBER OF THIRD AND FOURTH INSTARS PRODUCED FOR PARASITOID EXPOSURES, PROGRESS TOWARDS CONSISTENT PARASITISM OF EAB LARVAE REARED AND EXPOSED IN TWIN-SCREW EXTRUDED DIET, AND A METHOD TO ENHANCE PARASITISM OF DIET REARED EAB LARVAE THAT CAN BE USED AT THE MASS REARING FACILITY. EFFORTS WILL BENEFIT U.S. STATE AND GOVERNMENT AGENCIES WHO RELY ON ASH FORESTS, FOREST HEALTH AND ASH TREES IN URBAN LANDSCAPES, TRIBAL COMMUNITIES WHO UTILIZE ASH TREE MATERIALS IN TRADITIONAL CRAFTS, AS WELL AS THE U.S. PUBLIC WHO VISIT FORESTS CONTAINING ASH TREES AND/OR WHO OWN ASH TREES.

THE PRIMARY PURPOSE OF THIS AGREEMENT IS TO IMPROVE AN ARTIFICIAL DIET-BASED REARING SYSTEM FOR EMERALD ASH BORER (EAB) AND THE PARA SITOIDS BEING RELEASED TO CONTROL IT. THIS PROJECT SUPPORTS EFFORTS TO REAR AND RELEASE BIOLOGICAL CONTROL AGENTS TO SLOW THE SPREAD AND RATE OF DAMAGE CAUSED BY EAB. HUNDREDS OF THOUSANDS OF PARASITOID WASPS ARE REARED UNDER LABORATORY CONDITIONS AT THE EAB BIOCO NTROL REARING FACILITY IN BRIGHTON, MI AND DISTRIBUTED TO INFESTED AREAS FOR RELEASE. CURRENT REARING EFFORTS REQUIRE LIVE WOOD AND FOLIAGE TO MAINTAIN EAB REARING, WHICH IS DIFFICULT AND COSTLY. RELEASE OF BIOCONTROL AGENTS IS KEY TO THE RESTORATION OF ASH TREES AND MAINTENANCE OF FOREST ECOSYSTEMS ACROSS A LARGE PORTION OF THE UNITED STATES. STUDIES CONDUCTED FOR THIS AGREEMENT AIM TO INCREASE NEONATE TO LATE INSTAR LARVAL SURVIVAL THROUGH DIET NUTRITION AND TEXTURE OPTIMIZATION AND DEVELOPMENT OF A USEFUL LARVAL DIET PRESENTATION METHOD. THE OPTIMIZED DIET AND PRESENTATION METHOD WILL BE USED TO MAXIMIZE PARASITOID PRODUCTION FOR RELEASE TO CONTROL EAB.

RUI: COSMIC MICROWAVE BACKGROUND POLARIZATION ANALYSIS WITH UNDERGRADUATES

COLLABORATIVE RESEARCH: ROLE OF FLEXIBLE DESIGN AND INSTRUCTOR SUPPORTS IN IMPLEMENTING SUSTAINABLE COURSE-BASED RESEARCH EXPERIENCES ACROSS DIVERSE INSTITUTION TYPES

THE PRIMARY PURPOSE OF THIS AGREEMENT IS TO IMPROVE AN ARTIFICIALDIET-BASED REARING SYSTEM FOR EMERALD ASH BORER (EAB) AND THE PARASITOIDS BEING RELEASED TO CONTROL IT. THIS PROJECT SUPPORTS EFFORTS TO REAR AND RELEASE BIOLOGICAL CONTROL AGENTS TO SLOW THESPREAD AND RATE OF DAMAGE CAUSED BY EAB. HUNDREDS OF THOUSANDS OFPARASITOID WASPS ARE REARED UNDER LABORATORY CONDITIONS AT THE EAB BIOCONTROL REARING FACILITY IN BRIGHTON, MI AND DISTRIBUTED TO INFESTED AREAS FOR RELEASE. CURRENT REARING EFFORTS REQUIRE LIVE WOOD ANDFOLIAGE TO MAINTAIN EAB REARING, WHICH IS DIFFICULT AND COSTLY. RELEASEOF BIOCONTROL AGENTS IS KEY TO THE RESTORATION OF ASH TREES ANDMAINTENANCE OF FOREST ECOSYSTEMS ACROSS A LARGE PORTION OF THE UNITEDSTATES. STUDIES CONDUCTED FOR THIS AGREEMENT AIM TO INCREASE EGG TO LATEINSTAR LARVAL SURVIVAL THROUGH DIET NUTRITION AND TEXTURE OPTIMIZATIONAND DEVELOPMENT OF A USEFUL LARVAL DIET PRESENTATION METHOD. THEOPTIMIZED DIET AND PRESENTATION METHOD WILL BE USED TO MAXIMIZEPARASITOID PRODUCTION FOR RELEASE TO CONTROL EAB.

BASELINE SURVEYS FOR AMPHIBIANS AND PROTHONOTARY WARBLERS AT FORT A.P. HILL, VIRGINIA.

FULBRIGHT-HAYS - FACULTY RESEARCH ABROAD

DEVELOPING/IMPROVING A REARING SYSTEM FOR EMERALD ASH BORER

RESEARCH AND DEVELOPMENT ON A REARING SYSTEM FOR EMERALD ASHBORER

COLLABORATIVE RESEARCH: THE PROPER SCALE FOR ENVIRONMENTAL MARKETS WITH APPLICATION TO NITROGEN TRADING IN THE NEUSE RIVER BASIN

THE PURPOSE OF THIS AGREEMENT IS TO SAFEGUARD U.S. NURSERY PRODUCTIONTHROUGH THE DEVELOPMENT OF PEST MANAGEMENT TOOLS THAT WILL MINIMIZE THEINCIDENCE, SEVERITY, AND SPREAD OF BOX TREE MOTH ON BOXWOOD PLANTS. THISAGREEMENT FOCUSES ON PROACTIVELY DEVELOPING A METHOD TO STERILIZE MOTHSBY IRRADIATION IN PREPARATION FOR A POTENTIAL STERILE RELEASE PROGRAM TOCONTROL OR ERADICATE THE PEST. A STERILE INSECT PROGRAM WORKS BYFLOODING WILD POPULATIONS OF THE PEST WITH STERILIZED, LAB-REARED ADULTMALES THAT MATE WITH WILD FEMALES, RENDERING THEIR EGGS INVIABLE ANDREDUCING THE NUMBER OF DESTRUCTIVE CATERPILLARS IN THE FOLLOWINGGENERATIONS. THIS AGREEMENT WILL LEAD TO SELECTION OF THE APPROPRIATEDOSE OF RADIATION. IN CONJUNCTION WITH STERILIZING THE MOTHS, A STERILEINSECT RELEASE PROGRAM ALSO REQUIRES EFFICIENT REARING OF LARGE NUMBERSOF THE MOTHS FOR IRRADIATION AND RELEASE. THIS AGREEMENT ALSO FOCUSES ONDEVELOPING A LOW-COST SUBSTITUTE FOOD FOR BOX TREE MOTH CATERPILLARSTHAT DOES NOT REQUIRE LARGE NUMBERS OF EXPENSIVE BOXWOOD PLANTS.

DISTANT VIEWING TOOLKIT (DVT) FOR THE CULTURAL ANALYSIS OF MOVING IMAGES

EMSW21-MCTP: LONG-TERM UNDERGRADUATE RESEARCH EXPERIENCE (LURE)

THE PRIMARY PURPOSE OF THIS AGREEMENT IS TO SUPPORT REARING OF SEVERAL INVASIVE SPECIES THAT ARE USED IN PROJECTS TO SAFEGUARD NURSERY PRODUCTION, TEST FUMIGATION OPTIONS, SUPPORT MOLECULAR DIAGNOSTICS, AID DETECTOR DOG TRAINING, AND FOR OUTREACH DISPLAYS USED FOR EARLY DETECTION TRAINING. ACTIVITIES TO BE PERFORMED: THE RECIPIENT WILL PROVIDE ONE TECHNICIAN WHO WILL REAR TWO COLONIES OF BOX TREE MOTH: ONE COLONY USING PLANT MATERIAL TO SUPPORT BIOLOGICAL CONTROL STUDIES AND ONE COLONY REARED USING DIET WHICH WILL SUPPORT ALL OTHER STUDIES. THE TECHNICIAN WILL REAR A ROBUST COLONY OF EUROPEAN GRAPEVINE MOTH (EGVM) AND PROVIDE INSECTS FOR TESTING AND TREATMENT AS NEEDED. THEY WILL MAINTAIN QUALITY CONTROL METRICS FOR THE EGVM COLONY TO ENSURE HIGH QUALITY INSECTS CONTINUE TO BE PRODUCED. THEY WILL ALSO ASSIST WITH ASIAN LONGHORNED BEETLE (ALB) AND SPONGY MOTH (SM) REARING AND SUPPLY HIGH QUALITY INSECTS FOR VARIOUS ONGOING RESEARCH PROJECTS. THE PRINCIPAL INVESTIGATOR WILL, IN COOPERATION WITH THE APHIS PROJECT MANAGER, PROVIDE A DETAILED PROJECT WORK PLAN, SUPERVISE THE TECHNICIAN, PURCHASE SUPPLIES, AND WRITE REPORTS. DELIVERABLES AND EXPECTED OUTCOMES: THE GOAL OF THE AWARD IS 1) TO PROVIDE A RELIABLE SUPPLY OF BTM LIFE STAGES TO SUPPORT BIOCONTROL RESEARCH AND OTHER INTEGRATED PEST MANAGEMENT STUDIES, 2) TO PRODUCE ALB LIFE STAGES TO SUPPORT RESEARCH AND OUTREACH AND, 3) TO PRODUCE SPONGY MOTH LIFE STAGES TO SUPPORT RESEARCH AND PRODUCTION OF RIKER MOUNTS FOR EARLY DETECTION TRAINING. THE EXPECTED OUTCOME WILL BE SEVERAL ROBUST HIGH-QUALITY COLONIES OF I NSECTS WITH ADEQUATE NUMBERS OF EXPERIMENTAL INSECTS PROVIDED FOR RESEARCH. INTENDED BENEFICIARY(IES): THE PRIMARY BENEFICIARIES OF THIS AGREEMENT ARE THE U.S. NURSERY INDUSTRY IN 44 STATES THAT PRODUCE BOX TREES, SCIENTIST WITHIN SCIENCE AND TECHNOLOGY THAT CONDUCT INTEGRATED PEST MANAGEMENT RESEARCH, DETECTOR DOG TRAINING PROGRAMS AND STAKEHOLDERS THAT USE INVASIVE SPECIES RIKER MOUNTS FOR IDENTIFICATION TRAINING.

NUCLEAR STRUCTURE RESEARCH AT RICHMOND

COLLABORATIVE RESEARCH: WOMEN'S EMPOWERMENT, FOOD SECURITY AND FARM PRODUCTIVITY

NATURAL RESOURCE CONDITION ASSESSMENT: FORT MONROE NATIONAL MONUMENT (VIRGINIA), HARRIET TUBMAN UNDERGROUND RAILROAD NATIONAL MONUMENT (MARYLAND)

THE PURPOSE OF THIS AGREEMENT IS TO SAFEGUARD U.S. NURSERY PRODUCTION THROUGH THE DEVELOPMENT OF PEST MANAGEMENT TOOLS THAT WILL MINIMIZE THE INCIDENCE, SEVERITY, AND SPREAD OF BOX TREE MOTH (BTM) ON BOXWOOD PLANTS. THIS AGREEMENT FOCUSES ON DEVELOPING A METHOD TO MASS REAR BTM ON LOW-COST ARTIFICIAL DIET THAT DOES NOT REQUIRE LARGE NUMBERS OF EXPENSIVE BOXWOOD PLANTS, AND TO PROVIDE LARGE NUMBERS OF BTM LIFE STAGES FOR PESTICIDE STUDIES AND BIOCONTROL RESEARCH. THE RECIPIENT WILL PROVIDE ONE TECHNICIAN WHO WILL REAR BOX TREE MOTH IN CAGES, CARE FOR BOX TREE PLANTS IN A GREENHOUSE, CONDUCT THE RESEARCH ON ALTERNATE FOODS AS LAID OUT IN THE WORK PLAN, RECORD AND ENTER DATA ONTO PAPER AND ELECTRONIC DATA FILES, AND SUMMARIZE THE DATA. THE PRINCIPAL INVESTIGATOR WILL, IN COOPERATION WITH THE APHIS PROJECT MANAGER, PROVIDE A DETAILED PROJECT WORK PLAN, SUPERVISE THE TECHNICIANS, AND PURCHASE SUPPLIES. THE TECHNICIANS WILL ALSO SUPPORT PESTICIDE SCREENING ACTIVITIES AS LAID OUT IN A SEPARATE AGREEMENT WITH RUTGERS UNIVERSITY. THE GOAL OF THE AWARD IS TO PROVIDE BTM LIFE STAGES FOR RESEARCH ON REARING, PESTICIDE STUDIES AND BIOCONTROL EFFORTS AND TO MAKE PROGRESS TOWARDS DEVELOPMENT OF A SUBSTITUTE FOOD (ARTIFICIAL DIET) TO ENABLE LOW-COST, EFFICIENT LABORATORY REARING OF LARGE NUMBERS OF BTM. THE DELIVERABLE WILL BE ADEQUATE NUMBERS OF EXPERIMENTAL INSECTS PROVIDED FOR REARING AND PESTICIDE RESEARCH, AND DATA AND REPORTS ON RESULTS OF REARING TRIALS IN WHICH BTM CATERPILLARS ARE OFFERED MIXTURES OF INGREDIENTS AS FOOD. THE MAIN EXPECTED OUTCOME IS AN OPTIMIZED LARVAL DIET AND PROGRESS TOWARDS INCORPORATING THE DIET INTO THE REARING SYSTEM. THE PRIMARY BENEFICIARY OF THIS AGREEMENT IS THE U.S. NURSERY INDUSTRY IN 44 STATES THAT PRODUCE BOX TREES.

POPULATION PERSISTENCE AT AN INVASION FRONT: CLIMATIC LIMITATIONS ON THE SPREAD OF THE GYPSY MOTH

THE PRIMARY PURPOSE OF THIS AGREEMENT IS TO SUPPORT REARING PROJECTS FOR SEVERAL INVASIVE SPECIES TO SAFEGUARD NURSERY PRODUCTION, DEVELOP REARING SYSTEMS AND AID IN MAKING LURES FOR PEST DETECTION. THIS AGREEMENT FOCUSES ON DEVELOPING A METHOD TO MASS REAR BTM ON ARTIFICIAL DIET THAT DOES NOT REQUIRE LARGE NUMBERS OF EXPENSIVE BOXWOOD PLANTS, AND TO PROVIDE LARGE NUMBERS OF BTM LIFE STAGES FOR RESEARCH ON CONTROL OR ERADICATION OF THE PEST. THIS AGREEMENT WILL ALSO SUPPORT REARING SYSTEM DEVELOPMENT FOR EMERALD ASH BORER (EAB), REARING OF ASIAN LONGHORNED BEETLE (ALB) AND SPONGY MOTH AND CAPS LURE PRODUCTION. THE RECIPIENT WILL PROVIDE ONE TECHNICIAN WHO WILL REAR BOX TREE MOTH IN CAGES, CARE FOR BOX TREE PLANTS IN A GREENHOUSE, CONDUCT THE RESEARCH ON ARTIFICIAL DIET AS LAID OUT IN THE WORK PLAN, RECORD AND ENTER DATA ONTO PAPER AND ELECTRONIC DATA FILES, AND SUMMARIZE THE DATA. THE TECHNICIAN WILL ALSO ASSIST WITH ALB REARING, SPONGY MOTH PUPAL SORTING, CAPS LURE PRODUCTION AND EAB DIET MAKING. THE PRINCIPAL INVESTIGATOR WILL, IN COOPERATION WITH THE APHIS PROJECT MANAGER, PROVIDE A DETAILED PROJECT WORK PLAN, SUPERVISE THE TECHNICIAN, PURCHASE SUPPLIES, AND WRITE R EPORTS. THE GOAL OF THE AWARD IS TO PROVIDE BTM LIFE STAGES FOR RESEARCH ON REARING AND PESTICIDES AND TO MAKE PROGRESS TOWARDS DEVELOPMENT OF A SUBSTITUTE FOOD (ARTIFICIAL DIET) TO ENABLE LOW-COST, EFFICIENT LABORATORY REARING OF LARGE NUMBERS OF BTM. THE DELIVERABLE WILL BE ADEQUATE NUMBERS OF EXPERIMENTAL INSECTS PROVIDED FOR REARING AND PESTICIDE RESEARCH, AND DATA AND REPORTS ON RESULTS OF REARING TRIALS IN WHICH BTM CATERPILLARS ARE OFFERED MIXTURES OF INGREDIENTS AS FOOD. IN ADDITION, THE ALB AND SPONGY MOTH COLONIES WILL BE MAINTAINED, SEVERAL VERSIONS OF A TESTABLE EAB DIET WILL BE MADE AND CAPS LURE PRODUCTION WILL BE FULFILLED. THE PRIMARY BENEFICIARY OF THIS AGREEMENT IS THE U.S. NURSERY INDUSTRY IN 44 STATES THAT PRODUCE BOX TREES.

PROTOTYPING A DIGITAL TOOL FOR COMPUTER-ASSISTED ANNOTATION AND ANALYSIS OF MUSIC PERFORMANCE [VAST TROVES OF BOTH SOUND RECORDINGS AND MUSICAL SCORES HAVE BECOME WIDELY AVAILABLE IN THE DIGITAL ERA, BUT DRAWING CONNECTIONS BETWEEN THESE TWO MEDIUMS TO DEVELOP INSIGHTS ABOUT PERFORMANCE STYLE AND ARTISTIC EXPRESSION HAS REMAINED DIFFICULT AND TIME-CONSUMING. THIS PROJECT DEVELOPS A PROTOTYPE OF AN OPEN-SOURCE SOFTWARE TOOL TO FACILITATE STUDYING RECORDED MUSIC PERFORMANCES. OUR TOOL WILL ASSIST MUSIC SCHOLARS, ARCHIVISTS, AND ENTHUSIASTS IN COMPLEX MUSICAL ANALYSIS BY BOTH STREAMLINING THEIR WORKFLOWS AND EXPANDING THEIR CAPABILITIES, ENHANCED BY ADVANCED AI TECHNOLOGIES AND AN EASY-TO-USE GRAPHICAL INTERFACE, WITHOUT REQUIRING PROGRAMMING EXPERIENCE. TO OPTIMIZE USABILITY, OUR SOFTWARE DESIGN WILL BE INFORMED BY REAL-WORLD EXPERTS AND PROSPECTIVE USERS. THIS TOOL WILL ENABLE USERS TO EXAMINE PERFORMANCES AND SCORES IN A SINGLE INTEGRATED PROCESS, SCALE UP EXISTING RESEARCH, AND OPEN UP TRANSFORMATIVE NEW APPROACHES TO MUSICOLOGY AND MUSIC THEORY RESEARCH.]

BOX TREE MOTH SIT DEVELOPMENT

RUI: THEORETICAL NUCLEAR STRUCTURE STUDIES AT THE UNIVERSITY OF RICHMOND

RAPID - ABNORMAL BLEACHING IN CLIONA VARIANS IN THE FLORIDA KEYS: CONSEQUENCES FOR CORAL REEF HEALTH.

THIS AWARD WILL SUPPORT THE APEX OFFICER TRAINING SIMULATOR TO FURTHER THEIR EDUCATION WITH TRAINING AND RESOURCES FOR OUR OFFICERS AND THE COMMUNITY WE SERVE. THE INITIAL AND ONGOING ANNUAL TRAINING WILL ONLY ENHANCE THE WAY OUR OFFICERS INTERACT WITH AND COMMUNICATE WITH THE COMMUNITY WE SERVE AND PROTECT, AS WELL AS KEEP THE OFFICERS’ SKILLS AT A HIGHER LEVEL.

FULBRIGHT-HAYS - FACULTY RESEARCH ABROAD

REVSYS: RUI: DIVERSITY BEYOND MORPHOLOGY: A REVISION OF THE FROG GENUS LEPTODACTYLUS (AMPHIBIA, ANURA, LEPTODACTYLIDAE).

THE PURPOSE OF THIS AGREEMENT IS TO GENERATE DATA THAT SUPPORTS A NEW POST-HARVEST PHYTOSANITARY IRRADIATION TREATMENT FOR TWO-SPOT COTTON LEAFHOPPER, A DESTRUCTIVE AND INVASIVE PEST OF MANY AGRICULTURAL COMMODITIES, PARTICULARLY OKRA, EGGPLANT, AND COTTON. ADULT TWO-SPOT COTTON LEAFHOPPERS CAN DEPOSIT EGGS INTO OKRA FRUIT, WHICH INTRODUCES A RISK FOR DISPERSAL FROM ITS CURRENT RANGE TO KEY COTTON GROWING REGIONS IN THE UNITED STATES. DEVELOPING A NEW TREATMENT OPTION WILL IMPROVE PLANT PROTECTION AND QUARANTINE’S ABILITY TO LIMIT TWO-SPOT COTTON LEAFHOPPER SPREAD AND PROTECT AGRICULTURAL COMMODITIES WITHIN THE UNITED STATES. ACTIVITIES TO BE PERFORMED: ALL WORK WILL BE CONDUCTED WITHIN A SECURE QUARANTINE FACILITY AT THE FOREST PEST METHODS LABORATORY IN BUZZARDS BAY, MA, AND USING A LABORATORY TWO-SPOT COTTON LEAFHOPPER COLONY. INITIAL TESTING WILL FOCUS ON IDENTIFYING AN IRRADIATION TREATMENT DOSE THAT KILLS 99.9968% OF INDIVIDUALS, A STANDARD MEASURE FOR ESTABLISHING QUARANTINE SECURITY. FOR EACH LIFE STAGE OF THE TWO-SPOT COTTON LEAFHOPPER (EGGS, NYMPHS, AND ADULTS), 1000 INDIVIDUALS WILL BE EXPOSED TO ONE OF FIVE IRRADIATION DOSES RANGING FROM 0 TO 400 GY (200 INDIVIDUALS TESTED PER TREATMENT DOSE). AFTER IRRADIATION TREATMENT, INDIVIDUAL INSECTS WILL BE HELD AND MONITORED FOR (1) SURVIVAL TO ADULT EMERGENCE AND (2) PRODUCTION OF EGGS, WHICH WILL INDICATE IF THE TREATMENT HAD A STERILIZING EFFECT. DOSE RESPONSE CURVES WILL BE USED TO DETERMINE THE IRRADIATION DOSE THAT CAUSES 99.9968% MORTALITY AND STERILITY FOR EACH LIFE STAGE. FOR THE MOST RADIO-TOLERANT LIFE STAGE, ADDITIONAL TESTING WILL BE PERFORMED TO VALIDATE THE MINIMUM IRRADIATION TREATMENT DOSE THAT PROVIDES QUARANTINE SECURITY. A MINIMUM OF 10,000 INDIVIDUALS FROM THE LABORATORY COLONY WILL BE EXPOSED TO THE CANDIDATE TREATMENT DOSE, AND INSECTS WILL AGAIN BE MONITORED FOR SURVIVAL. DELIVERABLES AND EXPECTED OUTCOMES: DATA THAT IDENTIFIES THE MINIMUM IRRADIATION TREATMENT DOSE NEEDED TO KILL 99.9968% OF TSCL INDIVIDUALS. LARGE-SCALE VALIDATION DATASET TO CONFIRM THAT THE IDENTIFIED IRRADIATION TREATMENT DOSE WILL PROVIDE ACCEPTABLE QUARANTINE SECURITY LEVELS. THESE DATA WILL SUPPORT THE ADDITION OF A NEW TREATMENT SCHEDULE FOR TWO-SPOT COTTON LEAFHOPPER TO THE USDA TREATMENT MANUAL. INTENDED BENEFICIARY(IES): FLORIDA OKRA PRODUCERS AND EXPORTERS: IN MIAMI-DADE COUNTY, FLORIDA, WHERE TWO-SPOT COTTON LEAFHOPPER PRESSURE IS HIGH, OKRA (ABELMOSCHUS ESCULENTUS) IS A PREFERRED HOST PLANT FOR TSCL. OKRA IS AN IMPORTANT CROP COMMODITY FOR THE REGION; IT IS GROWN ON AN ESTIMATED 1,000 – 1,500 ACRES ACROSS MIAMI-DADE COUNTY, AND FRESH PODS ARE SOLD NATIONWIDE. IF QUARANTINE RESTRICTIONS FOR TWO-SPOT COTTON LEAFHOPPER ARE IMPLEMENTED IN FLORIDA, HAVING DATA-SUPPORTED PHYTOSANITARY TREATMENTS WILL BE CRITICAL FOR ENSURING THAT THIS MARKET REMAINS OPEN BOTH DOMESTICALLY AND INTERNATIONALLY. COTTON PRODUCERS: TWO-SPOT COTTON LEAFHOPPER IS A DEVASTATING PEST OF MULTIPLE CROPS, INCLUDING COTTON. PREVENTING ITS SPREAD WILL BENEFIT COTTON PRODUCERS WHO OPERATE OUTSIDE OF ITS CURRENT RANGE. FOR EXAMPLE, MORE THAN 150,000 ACRES IN COTTON ARE PLANTED ANNUALLY IN CALIFORNIA, A STATE THAT DOES NOT CURRENTLY HAVE TWO-SPOT COTTON LEAFHOPPER.

LANDSCAPES OF THE AMERICAN PAST: VISUALIZING EMANCIPATION

AMERICA?S MUSIC SCENES IN THE AGE OF SOCIAL MEDIA

2014 SPRING TOPOLOGY AND DYNAMICS CONFERENCE

EVALUATING POTENTIAL NATIONAL NATURAL LANDMARKS (NNL)

CPS: SMALL: COLLABORATIVE RESEARCH: TOWARDS SECURE, PRIVACY-PRESERVING, VERIFIABLE CYBERPHYSICAL SYSTEMS

FIELD-INITIATED PROGRAM

CONFERENCE PROPOSAL: THE RADIO SYNCHROTRON BACKGROUND

COLLABORATIVE RESEARCH: SIMULATION OF SYSTEMATIC EFFECTS IN INTERFEROMETRY FOR STUDIES OF THE COSMIC MICROWAVE BACKGROUND

CONFERENCE: VIRGINIA OPERATOR THEORY AND COMPLEX ANALYSIS MEETING -THIS AWARD SUPPORTS THE VIRGINIA OPERATOR THEORY AND COMPLEX ANALYSIS MEETING, TO BE HELD AT THE UNIVERSITY OF RICHMOND IN FALL 2023, FALL 2024, AND FALL 2025. ESTABLISHED IN 1992, THE VIRGINIA OPERATOR THEORY AND COMPLEX ANALYSIS MEETING IS A ONE-DAY EVENT WHICH CONVENES RESEARCHERS IN VIRGINIA, NORTH CAROLINA, AND NEIGHBORING STATES WORKING IN VARIOUS FIELDS BOTH WITHIN AND ADJACENT TO THE MATHEMATICAL DISCIPLINE OF ANALYSIS. SUBJECTS TO BE DISCUSSED INCLUDE CORE AREAS OF ANALYSIS AS WELL AS EMERGING APPLICATION DOMAINS SUCH AS QUANTUM COMPUTING. THE EVENT AFFORDS EARLY CAREER RESEARCHERS, ESPECIALLY GRADUATE STUDENTS, OPPORTUNITIES TO MEET NEW MATHEMATICAL COLLEAGUES AND TO DISSEMINATE THEIR RESEARCH IDEAS TO A WIDER AUDIENCE. AT THE SAME TIME, THE SMALL SIZE OF THESE EVENTS FOSTERS COMMUNITY INTERACTION AND PROMOTES INCREASED DIALOGUE AND NETWORKING FOR THE BENEFIT OF ALL PARTICIPANTS. THE VIRGINIA OPERATOR THEORY AND COMPLEX ANALYSIS MEETING IS A REGIONAL MEETING OF MATHEMATICIANS WORKING IN THE FIELDS OF OPERATOR THEORY, COMPLEX ANALYSIS, BANACH SPACES, AND OPERATOR ALGEBRAS. THE MEETING ALSO PLACES EMPHASIS ON NEW CONNECTIONS AND INTERACTIONS BETWEEN THESE SUBJECTS AND ADJACENT AND EMERGING FIELDS SUCH AS QUANTUM COMPUTING AND MATHEMATICAL PHYSICS. THE CONFERENCE OFFERS A WELCOMING ENVIRONMENT FOR PEOPLE NEW TO THE DISCIPLINE OF ANALYSIS AND TO MATHEMATICS AND PROMOTES THE EXCHANGE OF IDEAS AMONG RESEARCHERS IN ANALYSIS AND RELATED FIELDS IN THE MID-ATLANTIC AND SOUTHEAST REGIONS. HTTPS://VOTCAM.WORDPRESS.COM THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

PURPOSE: TO SUPPORT THE COMMISSIONING AND PRESENTATION OF MULTIDISCIPLINARY PERFORMANCES.

CONFERENCE: SOUTHEASTERN ANALYSIS MEETING -THE SOUTHEASTERN ANALYSIS MEETING (SEAM) IS A CONFERENCE TO BE HELD AT THE UNIVERSITY OF RICHMOND (RICHMOND, VIRGINIA) ON THE WEEKEND OF MARCH 13 - 15, 2026. THE SEAM HAS BEEN HELD ANNUALLY AT A UNIVERSITY IN THE SOUTHEASTERN UNITED STATES SINCE 1985. IT HAS ESTABLISHED ITSELF AS A LEADING NATIONAL VENUE FOR MATHEMATICAL ANALYSIS, WITH A MISSION OF FACILITATING INTERACTION AND COLLABORATION BETWEEN RESEARCHERS AT ALL CAREER STAGES. IT ENCOURAGES RESEARCH AND EDUCATION IN THE FIELD OF ANALYSIS. THE PROGRAM OF SEAM INCLUDES PLENARY TALKS BY SIX SELECTED PARTICIPANTS AND 20-MINUTE CONTRIBUTED TALKS OPEN TO ALL PARTICIPANTS AS WELL AS PROFESSIONAL DEVELOPMENT ACTIVITIES SUCH AS PROBLEM SESSIONS FOR EARLY CAREER RESEARCHERS. THIS FORMAT FOSTERS COLLEGIALITY AND A VIBRANT ENVIRONMENT THAT ENCOURAGES THE EXCHANGE OF IDEAS, NETWORKING, AND THE FORMATION AND DEVELOPMENT OF COLLABORATIONS. HISTORICALLY, THE TOPICS OF THE MAIN LECTURES HAVE REFLECTED THE MAJOR CURRENT DEVELOPMENTS IN ANALYSIS, EMPHASIZING THE MEETING?S TRADITIONAL THEMES. THIS SEAM WILL FEATURE SIX PLENARY TALKS ON SUBJECTS SUCH AS GEOMETRIC FUNCTION THEORY, HARMONIC ANALYSIS, PARTIAL DIFFERENTIAL EQUATIONS, AND THE ANALYSIS OF THE SCHR?DINGER EQUATION, CONVEX GEOMETRY AND OPTIMAL CONTROL, OPERATOR THEORY AND OPERATOR ALGEBRAS, AND MULTI-DIMENSIONAL COMPLEX ANALYSIS. THE WEBSITE OF THE CONFERENCE IS HTTPS://SITES.GOOGLE.COM/VIEW/SEAM42/HOME . THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

FINITE FIELDS AND THEIR APPLICATIONS AT SIMON FRASER UNIVERSITY

RAPID: EFFECTS OF HURRICANE IRMA ON SHALLOW-WATER MARINE ECOSYSTEMS: ASSESSING RESILIENCY OF SPONGE AND MACROINVERTEBRATE COMMUNITIES IN THE FLORIDA KEYS

INVESTIGATION OF IRON ACQUISITION GENES IN SODALIS GLOSSINIDIUS USING NEW TOOLS.

STUDENT TRAVEL SUPPORT FOR THE 2017 IEEE INTERNATIONAL SYMPOSIUM ON PERFORMANCE ANALYSIS OF SYSTEMS AND SOFTWARE (ISPASS-2017)

P19AC00084

NATURAL RESOURCE CONDITION ASSESSMENT: PETE & BOWA

DISABILITY REHABILITATION RESEARCH PROJECTS

EXECUTE A BALANCED SCIENCE PROGRAM BASED ON DISCIPLINE-SPECIFIC GUIDANCE FROM THE NATIONAL ACADEMIES OF SCIENCES ENGINEERING AND MEDICINE ADMINISTRATION PRIORITIES AND DIRECTION FROM CONGRESS. PARTICIPATE AS A KEY PARTNER AND ENABLER IN THE AGENCY S EXPLORATION INITIATIVE FOCUSING ON SCIENTIFIC RESEARCH OF ON AND FROM THE MOON LUNAR ORBIT MARS AND BEYOND. ADVANCE DISCOVERY IN EMERGING FIELDS BY IDENTIFYING AND EXPLOITING CROSS-DISCIPLINARY OPPORTUNITIES BETWEEN TRADITIONAL SCIENCE DISCIPLINES DEVELOP A DIRECTORATE-WIDE TARGET-USER FOCUSED APPROACH TO APPLIED PROGRAMS INCLUDING EARTH SCIENCE APPLICATIONS SPACE WEATHER PLANETARY DEFENSE AND SPACE SITUATIONAL AWARENESS.

POPULATION PERSISTENCE AT AN INVASION FRONT: CLIMATIC LIMITATIONS ON THE SPREAD OF THE GYPSY MOTH

NUCLEAR STEWARD RESEARCH AT THE UNIVERSITY OF RICHMOND