Oasis Inc

NATIONAL VOLUNTEER CAREGIVER PROGRAM

COMMUNITY CARE CORPS: EXPANSION AND REFINEMENT OF VOLUNTEER ASSISTANCE MODELS

IMPACT AID PROGRAM TITLE VIII SECTION 8003 AND SECTION 8007(A)

IMPACT AID PROGRAM TITLE VIII SECTION 8003

IMPACT AID PROGRAM, TITLE VIII, SECTION 8003

IMPACT AID PROGRAM TITLE VIII SECTION 8003

IMPACT AID PROGRAM TITLE VIII SECTION 8003

DEVELOPMENT OF PAR2 PEPDUCINS AS A NOVEL NASH TREATMENT

PURCHASE LAND AND PROVIDE TECHNICAL ASSISTANCE TO FARMERS TO INCREASE CAPITAL AND MARKET ACCESS.

INTEGRATED MAT FOR FAMILIES AFFECTED BY OPIOID USE DISORDER - PROJECT NAME: INTEGRATED MAT FOR FAMILIES AFFECTED BY OPIOID USE DISORDER. SUMMARY: THE OASIS CENTER OF THE ROGUE VALLEY (OASIS) PROPOSES A FAMILY-CENTERED PROGRAM OF INTEGRATED PRIMARY CARE, BEHAVIORAL HEALTH, AND RECOVERY SUPPORT SERVICES FOR PARENTING ADULTS WITH OPIOID USE DISORDER (OUD) AND THEIR CHILDREN IN SOUTHERN OREGON. TARGETED OUTREACH WILL BE PROVIDED TO HIGH-RISK POPULATIONS INCLUDING UNHOUSED, HOSPITALIZED, AND RECENTLY INCARCERATED INDIVIDUALS. A MAJORITY OF OASIS FAMILIES LIVE IN POVERTY, AND APPROXIMATELY ONE-THIRD ARE CHILD WELFARE INVOLVED AND ONE-THIRD ARE COMMUNITY JUSTICE INVOLVED. OREGON IS RANKED FIRST NATIONALLY FOR ILLICIT DRUG ABUSE IN THE PAST YEAR, AND LAST IN THE NATION IN RESIDENTS NEEDING, BUT NOT RECEIVING, SUBSTANCE USE DISORDER TREATMENT (MHACBO). 18.6% OF OASIS CLIENTS IDENTIFY ETHNICITY AS OTHER THAN WHITE. OUD AND OVERDOSE DEATHS ARE SEVERE PROBLEMS IN OREGON AND IN THE OASIS SERVICE AREA IN PARTICULAR. THE OREGON HEALTH AUTHORITY (OHA) REPORTS (2018, THE MOST RECENT COUNTY-SPECIFIC DATA) OVERDOSE HOSPITALIZATIONS IN JACKSON AND JOSEPHINE COUNTIES WERE 112.0 AND 136.2 PER 100,000 COMPARED TO 97.0 PER 100,000 FOR THE STATE. THE 3-YEAR (2016-2018) DRUG OVERDOSE DEATH RATES FOR THE COUNTIES WERE 30.5 AND 27.5 PER 100,000 RESIDENTS RESPECTIVELY, ALMOST THREE TIMES HIGHER THAN THE STATEWIDE RATE OF 13.2 PER 100,000. THERE IS A SPIKE IN OVERDOSE DEATHS ATTRIBUTED TO GREATER DANGER FROM FENTANYL IN THE DRUG SUPPLY. IN JACKSON COUNTY FATAL OVERDOSES INCREASED 115% FROM 2020 TO 2021 (JCME). THIS PROJECT RESPONDS TO URGENT NEEDS IN JACKSON COUNTY: TO INCREASE COMMUNITY OUD RECOVERY CAPACITY, MITIGATE THE IMPACTS OF SUBSTANCE USE AND OVERDOSE ON INDIVIDUALS AND FAMILIES, SUPPORT CHILDREN’S HEALTHY DEVELOPMENT, AND REDUCE THE NEGATIVE INTERGENERATIONAL IMPACTS OF OUD. THE PROJECT GOALS ARE 1) DECREASE ILLICIT OPIOID USE, 2) INCREASE ACCESS AND ENGAGEMENT WITH MEDICATION FOR OPIOID USE DISORDER (MOUD), 3) REDUCE OVERDOSE AND DIVERSION RISK BY ADULTS WITH OUD, 4) REDUCE THE IMPACT OF ADDICTION ON FAMILY MEMBERS OF CLIENTS WITH OUD, 5) INCREASE TREATMENT RETENTION THROUGH INTEGRATED PRIMARY AND BEHAVIORAL HEALTH CARE, WELLNESS ACTIVITIES, AND EMPLOYMENT AND HOUSING SUPPORT, 6) INCREASE LONG-TERM FUNDING MECHANISMS FOR CLINIC SUSTAINABILITY. STRATEGIES AND INVENTIONS INCLUDE HIRING AN ADDITIONAL PHYSICIAN TO MANAGE MEDICATION AND TO SUPPORT PATIENTS WITH OPIOID USE DISORDER (MOUD FOR OUD) AND THEIR YOUNG CHILDREN, HIRE A COMMUNITY HEALTH COORDINATOR TO SUPPORT HARM REDUCTION ACTIVITIES, CARE COORDINATE FOR LARGE OASIS HEPATITIS C COHORT, AND FACILITATE A HIGH-SYSTEM INVOLVED MULTI-DISCIPLINARY TEAM (MDT) OF COMMUNITY PARTNERS. ADDITIONALLY, OASIS PROPOSES HIRING A CHILDREN’S COORDINATOR TO PROVIDE TARGETED PARENTING SUPPORT AND TO ENSURE CHILDREN OF PARENTS WITH OUD RECEIVE FULL ARRAY OF SUPPORTIVE AND HEALTH-RELATED SERVICES. OASIS WILL ALSO HIRE A BILINGUAL PEER SUPPORT SPECIALIST FOR OUTREACH, ENGAGEMENT, AND RECOVERY SUPPORT AND WILL EMBED AN EMPLOYMENT SUPPORT SPECIALIST WITHIN THE CLINIC TO SUPPORT PARENTS WITH BARRIERS TO EMPLOYMENT. THIS FIVE-YEAR PROJECT WILL SERVE 50 UNDUPLICATED ADULTS AND THEIR FAMILIES DURING EACH YEAR OF THE PROJECT FOR A TOTAL UNDUPLICATED NUMBER SERVED OF 250 ADULTS. THIS PROPOSAL HAS A STRONG FOCUS ON IMPROVING ACCESS TO DIVERSE POPULATIONS, PROVIDING TRAUMA-INFORMED CARE, AND WORKING CLOSELY WITH COMMUNITY PARTNERS TO SERVE FAMILIES IMPACTED BY OUD. SERVICES WILL BE PROVIDED BY OASIS OR ONSITE THROUGH EMBEDDED PROVIDERS FROM ONTRACK ROGUE VALLEY, NATHAN BEARD JOB DEVELOPMENT, MAX’S MISSION, AND OTHER COMMUNITY PROVIDERS.

DEVELOPMENT OF PAR2 INHIBITORS FOR THE TREATMENT OF NONALCOHOLIC STEATOHEPATITIS

LIPID RECEPTOR GPR31 AS A TARGET FOR ANTI-THROMBOTIC AND STROKE THERAPY - DESPITE PREVALENT USE OF ANTI-PLATELET AND ANTI-LIPID THERAPIES, STROKE REMAINS THE THIRD MAJOR CAUSE OF DEATH AND IS THE LEADING CAUSE OF ADULT DISABILITY IN THE US WITH AN ESTIMATED COST IN THE RANGE OF $34 BILLION ANNUALLY. APPROXIMATELY 20% OF THE ANNUAL 795,000 STROKE PATIENTS DIE WITHIN ONE YEAR AND 15-30% ARE PERMANENTLY DISABLED. ANTIPLATELET THERAPY IS MAINLY USED FOR PRIMARY PREVENTION OF ACUTE ISCHEMIC STROKE IN CEREBROVASCULAR DISEASE. BIOACTIVE FATTY ACIDS ARE A NEW CLASS OF MOLECULAR TARGETS THAT HOLD GREAT THERAPEUTIC POTENTIAL BECAUSE OF THEIR DIVERSE ROLE AS SIGNALING MOLECULES THAT REGULATE METABOLISM AND INFLAMMATION. THE OXIDATION OF ARACHIDONIC ACID BY 12-LOX RESULTS IN THE PRODUCTION OF A NUMBER OF BIOACTIVE LIPIDS INCLUDING THE METABOLITE 12(S)-HETE. THE LIPID RECEPTOR GPR31, AN ORPHAN CLASS A GPCR, IS A 12(S)- HETE RECEPTOR RECENTLY SHOWN TO BE INVOLVED IN INFLAMMATORY SIGNALING. WE RECENTLY DISCOVERED THAT GPR31 MEDIATES 12(S)-HETE PROTHROMBOTIC SIGNALING IN PLATELETS AND PROMOTES GLUTAMATE-INDUCED OXIDATIVE TOXICITY IN NEURONAL CELLS. THEREFORE, WE PROPOSE THAT TARGETING GPR31 MAY PROVIDE A THERAPEUTIC PATH TOWARDS DEVELOPMENT OF A SAFE AND EFFECTIVE ANTIPLATELET THERAPY THAT IS COUPLED WITH SECONDARY NEUROPROTECTIVE EFFECTS FOR MITIGATING AGAINST THE ACUTE NEUROLOGIC SEQUELA OF STROKE TO PROVIDE A MORE EFFECTIVE AND SAFER ALTERNATIVE OPTION OR ADJUNCT TO FIBRINOLYTIC THERAPY. WE HAVE RECENTLY SUCCEEDED IN IDENTIFYING THE FIRST EFFECTIVE GPR31 ANTAGONIST USING OUR CELL-PENETRATING, MEMBRANE-TETHERED, PEPDUCIN TECHNOLOGY TO BE VALIDATED IN THESE PRECLINICAL IND-ENABLING STUDIES AS AN ANTI-PLATELET AND ANTI-STROKE AGENT. WE SHOW HERE THAT THIS I3-LOOP DERIVED GPR31 LIPOPEPTIDE HAS POTENT ANTIPLATELET ACTIVITY AND NEARLY COMPLETELY SUPPRESSES ARTERIAL THROMBOSIS WITHOUT AN EFFECT ON HEMOSTASIS IN MICE. PRELIMINARY DATA WITH THE GPR310 PEPDUCIN SHOWS A HIGHLY SIGNIFICANT REDUCTION IN STROKE INFARCT AREA IN MICE SIMILAR TO THE PROTECTIVE EFFECT OF GPR31-DEFICIENCY. FURTHERMORE, WE PROVIDE EVIDENCE FOR A DIRECT NEUROPROTECTIVE EFFECT OF THE GPR310 PEPDUCIN ON HT22 NEURONAL CELLS SUBJECTED TO GLUTAMATE MEDIATED OXIDATIVE STRESS. THE GOAL OF THIS PHASE 2 STTR PROJECT IS TO DEVELOP THE GPR310 PEPDUCIN AS A COLLABORATIVE EFFORT BETWEEN OASIS PHARMACEUTICALS (LEXINGTON, MA), TUFTS MEDICAL CENTER (BOSTON, MA) THAT WOULD PROVIDE A ROBUST IND DATA PACKAGE REQUIRED TO ADVANCE THE INITIAL COMMERCIAL DEVELOPMENT OF THE FIRST GPR31 INHIBITOR AS A DUAL ANTIPLATELET, ANTI-STROKE DRUG. THIS DRUG DEVELOPMENT PROGRAM WOULD ESTABLISH THE SCIENTIFIC MERIT OF THE GPR31 TARGET BY ACCOMPLISHING THE MAJOR MILESTONES AT THE END OF 2 YEARS OF GLP SAFETY/PHARMACOLOGY AND EFFICACY IN STROKE MODELS ± THROMBOLYTIC THERAPY TO SUPPORT A PHASE I FIRST-IN-HUMAN CLINICAL TRIAL.

SUPPORTIVE HOUSING FOR PERSONS WITH DISABILITIES

TAS::89 0336::TAS RECOVERY WATER CARBON NANOTUBES FOR REVERSE OSMOSIS MEMBRANES THAT REQUIRE LESS ENERGY AND HAVE MANY TIMES HIGHER FLUX. COULD DR

DEVELOPMENT OF PAR2 PEPDUCINS FOR THE TREATMENT OF ATOPIC DERMATITIS

PAR2 PEPDUCINS AS A NOVEL TREATMENT OF IDIOPATHIC PULMONARY FIBROSIS

PURPOSE: THE CONTINUUM OF CARE (COC) PROGRAM IS DESIGNED TO PROMOTE COMMUNITY-WIDE COMMITMENT TO THE GOAL OF ENDING HOMELESSNESS; PROVIDE FUNDING FOR EFFORTS BY NONPROFIT PROVIDERS, STATES, AND LOCAL GOVERNMENTS TO QUICKLY HOUSE HOMELESS INDIVIDUALS AND FAMILIES WHILE MINIMIZING THE TRAUMA AND DISLOCATION CAUSED TO HOMELESS INDIVIDUALS, FAMILIES, AND COMMUNITIES BY HOMELESSNESS; PROMOTE ACCESS TO AND EFFECTIVE UTILIZATION OF MAINSTREAM PROGRAMS BY HOMELESS INDIVIDUALS AND FAMILIES; AND OPTIMIZE SELF-SUFFICIENCY AMONG INDIVIDUALS AND FAMILIES EXPERIENCING HOMELESSNESS. THE COC PROGRAM INCLUDES GRANTS THAT ARE AVAILABLE TO SPECIFIC SUBPOPULATIONS OF PEOPLE EXPERIENCING HOMELESSNESS. THE GRANTS SPECIFICALLY SERVE YOUTH, DEFINED AS HOUSEHOLDS WHERE NO PERSON IS OVER THE AGE OF 24 UNDER THE YOUTH HOMELESS DEMONSTRATION PROGRAM (YHDP). THE GOAL OF THE YOUTH HOMELESSNESS DEMONSTRATION PROGRAM (YHDP) IS TO SUPPORT THE DEVELOPMENT AND IMPLEMENTATION OF A COORDINATED COMMUNITY APPROACH TO PREVENTING AND ENDING YOUTH HOMELESSNESS AND SHARING THAT EXPERIENCE WITH AND MOBILIZING COMMUNITIES AROUND THE COUNTRY TOWARD THE SAME END. THE NOTICE OF FUNDING OPPORTUNITY (NOFO) FOR NEW YHDP GRANTS IS FOUND AT HTTPS://WWW.HUD.GOV/PROGRAM_OFFICES/COMM_PLANNING/YHDP (CHOOSE THE MOST RECENT YHDP NOFO LISTED). THE NOFO FOR YHDP RENEWALS AND REPLACEMENTS IS FOUND AT HTTPS://WWW.HUD.GOV/PROGRAM_OFFICES/COMM_PLANNING/COC/COMPETITION (CHOOSE THE MOST RECENT COC/YHDP RENEWAL OR REPLACEMENT NOFO LISTED).; ACTIVITIES TO BE PERFORMED: THESE GRANTS MAY BE USED TO PAY FOR THE ELIGIBLE COSTS USED TO ESTABLISH AND OPERATE PROJECTS UNDER FIVE PROGRAM COMPONENTS: 1. PERMANENT HOUSING, WHICH INCLUDES PERMANENT SUPPORTIVE HOUSING FOR PERSONS WITH DISABILITIES, AND RAPID REHOUSING; 2. TRANSITIONAL HOUSING; 3. SUPPORTIVE SERVICES ONLY; 4. HOMELESS MANAGEMENT INFORMATION SYSTEMS (HMIS); AND 5. HOMELESSNESS PREVENTION (IN SOME CASES). ELIGIBLE COSTS WITHIN THESE PROJECTS INCLUDE: 1. LEASING OF A STRUCTURE OR STRUCTURES, OR PORTIONS THEREOF, TO PROVIDE HOUSING OR SUPPORTIVE SERVICES; 2. RENTAL ASSISTANCE, WHICH MAY BE SHORT-TERM, MEDIUM-TERM, OR LONG-TERM, AS WELL AS TENANT-BASED, PROJECT-BASED, OR SPONSOR-BASED, FOR TRANSITIONAL OR PERMANENT HOUSING; 3. SUPPORTIVE SERVICES TO ASSIST PROGRAM PARTICIPANTS OBTAIN AND MAINTAIN HOUSING; 4. OPERATING COSTS OF SUPPORTIVE HOUSING; 5. COSTS OF IMPLEMENTING AND OPERATING HMIS; 6. PROJECT ADMINISTRATIVE COSTS; 7. RELOCATION COSTS; AND 8. INDIRECT COSTS IN ACCORDANCE WITH 2 CFR PARTS 200, AS APPLICABLE. IN ADDITION TO USING GRANT FUNDS FOR THE ELIGIBLE COSTS DESCRIBED ABOVE, RECIPIENTS AND SUBRECIPIENTS IN CONTINUUMS OF CARE DESIGNATED AS HIGH PERFORMING COMMUNITIES MAY ALSO USE GRANT FUNDS TO PROVIDE HOUSING RELOCATION AND STABILIZATION SERVICES AND SHORT- AND/OR MEDIUM-TERM RENTAL ASSISTANCE TO YOUTH AT RISK OF HOMELESSNESS AS SET FORTH IN 24 CFR 576.103 AND 24 CFR 576.104, IF NECESSARY TO PREVENT YOUTH FROM BECOMING HOMELESS. NO ASSISTANCE PROVIDED UNDER PROGRAM (OR ANY STATE OR LOCAL GOVERNMENT FUNDS USED TO SUPPLEMENT THIS ASSISTANCE) MAY BE USED TO REPLACE STATE OR LOCAL FUNDS PREVIOUSLY USED, OR DESIGNATED FOR USE, TO ASSIST HOMELESS PERSONS OR PERSONS AT-RISK OF HOMELESSNESS.; EXPECTED OUTCOMES: DECREASE IN THE NUMBER OF YOUTH EXPERIENCING HOMELESSNESS, MORE SPECIFICALLY USING PERFORMANCE INDICATORS SUCH AS THE LENGTH OF TIME HOMELESS, RETURNS TO HOMELESSNESS OVER TIME, AND EXITS TO PERMANENT HOUSING. COC PERFORMANCE PROFILE REPORTS CAN BE FOUND AT: HTTPS://WWW.HUDEXCHANGE.INFO/PROGRAMS/COC/COC-PERFORMANCE-PROFILE-REPORTS/; INTENDED BENEFICIARIES: YOUTH DEFINED AS HOUSEHOLDS WHERE NO PERSON IS OVER THE AGE OF 24; SUBRECIPIENT ACTIVITIES: THE SUBRECIPIENT ACTIVITIES ARE UNKNOWN AT THE TIME OF AWARD

PHASE II OF VEROFY: A NEW TOOL TO IMPROVE PRODUCTIVITY FOR STRESS RESEARCH

CONTINUUM OF CARE PROGRAM

CONTINUUM OF CARE PROGRAM

CONTINUUM OF CARE PROGRAM

CONTINUUM OF CARE PROGRAM

OASIS CENTER'S PREVENTION PROGRAM

YOUTH - YOUNG OFFENDER

JUSTICE FOR VICTIMS PARTNERSHIP BETWEEN VICTIM SERVICE PROVIDER OASIS SHELTER HOME AND THE CURRY COUNTY DISTRICT ATTORNEY'S OFFICE IN CURRY COUNTY OREGON.

TLP

VIRTUAL HEALTHY HABITS: AN INNOVATIVE APPROACH TO NUTRITION EDUCATION, HANDS-ON MEAL PREPARATION AND SOCIALIZING FOR OLDER ADULTS

THIS AWARD FUNDS THE APPROVED 2023?24 RSVP PROGRAM. YOUR 2023?24 STATUTORY MATCH IS 30% AND YOUR BUDGETARY MATCH IS 30.0%. THIS AWARD REDUCES THE 2023-24 PROGRAM YEAR BY THREE MONTHS FOR THE PURPOSE OF ALIGNING THE AWARD WITH NON?STIPEND PROGRAM START DATES. THE 2024-25 PROGRAM YEAR GRANT WILL HAVE AN APRIL 1 START DATE.

COMMUNITY PROJECT FUNDING/CONGRESSIONALLY DIRECTED SPENDING - CONSTRUCTION

TRANSITIONAL LIVING PROGRAM FOR RUNAWAY AND HOMELESS YOUTH

THIS AWARD FUNDS THE APPROVED 2023-24 RSVP PROGRAM. YOUR 2023-24 STATUTORY MATCH IS 30% AND YOUR BUDGETARY MATCH IS 30.0%.

THE PROJECT FOCUSES ON ADDRESSING RECIDIVISM AMONG YOUTH EXITING THE JUVENILE JUSTICE SYSTEM IN LOUISIANA BY PROVIDING THE YOUTH OASIS RESILIENT FUTURES PROGRAM. THIS IS A COMMUNITY-BASED REENTRY PROGRAM SUPPORTING THE SUCCESSFUL TRANSITION OF YOUTH (AGES 1622) BACK INTO THEIR COMMUNITIES. SERVICES INCLUDE PRE-RELEASE CASE MANAGEMENT, HOUSING ASSISTANCE, SKILL-BUILDING ACROSS SIX DOMAINS, AND COMMUNITY LINKAGES TO MEET INDIVIDUAL NEEDS.

YOUTH OASIS TRANSITIONAL LIVING PROGRAM

PURPOSE: THE CONTINUUM OF CARE (COC) PROGRAM IS DESIGNED TO PROMOTE COMMUNITY-WIDE COMMITMENT TO THE GOAL OF ENDING HOMELESSNESS; PROVIDE FUNDING FOR EFFORTS BY NONPROFIT PROVIDERS, STATES, AND LOCAL GOVERNMENTS TO QUICKLY HOUSE HOMELESS INDIVIDUALS AND FAMILIES WHILE MINIMIZING THE TRAUMA AND DISLOCATION CAUSED TO HOMELESS INDIVIDUALS, FAMILIES, AND COMMUNITIES BY HOMELESSNESS; PROMOTE ACCESS TO AND EFFECTIVE UTILIZATION OF MAINSTREAM PROGRAMS BY HOMELESS INDIVIDUALS AND FAMILIES; AND OPTIMIZE SELF-SUFFICIENCY AMONG INDIVIDUALS AND FAMILIES EXPERIENCING HOMELESSNESS. THE COC PROGRAM INCLUDES GRANTS THAT ARE AVAILABLE TO SPECIFIC SUBPOPULATIONS OF PEOPLE EXPERIENCING HOMELESSNESS. THE GRANTS SPECIFICALLY SERVE YOUTH, DEFINED AS HOUSEHOLDS WHERE NO PERSON IS OVER THE AGE OF 24 UNDER THE YOUTH HOMELESS DEMONSTRATION PROGRAM (YHDP). THE GOAL OF THE YOUTH HOMELESSNESS DEMONSTRATION PROGRAM (YHDP) IS TO SUPPORT THE DEVELOPMENT AND IMPLEMENTATION OF A COORDINATED COMMUNITY APPROACH TO PREVENTING AND ENDING YOUTH HOMELESSNESS AND SHARING THAT EXPERIENCE WITH AND MOBILIZING COMMUNITIES AROUND THE COUNTRY TOWARD THE SAME END. THE NOTICE OF FUNDING OPPORTUNITY (NOFO) FOR NEW YHDP GRANTS IS FOUND AT HTTPS://WWW.HUD.GOV/PROGRAM_OFFICES/COMM_PLANNING/YHDP (CHOOSE THE MOST RECENT YHDP NOFO LISTED). THE NOFO FOR YHDP RENEWALS AND REPLACEMENTS IS FOUND AT HTTPS://WWW.HUD.GOV/PROGRAM_OFFICES/COMM_PLANNING/COC/COMPETITION (CHOOSE THE MOST RECENT COC/YHDP RENEWAL OR REPLACEMENT NOFO LISTED).; ACTIVITIES TO BE PERFORMED: THESE GRANTS MAY BE USED TO PAY FOR THE ELIGIBLE COSTS USED TO ESTABLISH AND OPERATE PROJECTS UNDER FIVE PROGRAM COMPONENTS: 1. PERMANENT HOUSING, WHICH INCLUDES PERMANENT SUPPORTIVE HOUSING FOR PERSONS WITH DISABILITIES, AND RAPID REHOUSING; 2. TRANSITIONAL HOUSING; 3. SUPPORTIVE SERVICES ONLY; 4. HOMELESS MANAGEMENT INFORMATION SYSTEMS (HMIS); AND 5. HOMELESSNESS PREVENTION (IN SOME CASES). ELIGIBLE COSTS WITHIN THESE PROJECTS INCLUDE: 1. LEASING OF A STRUCTURE OR STRUCTURES, OR PORTIONS THEREOF, TO PROVIDE HOUSING OR SUPPORTIVE SERVICES; 2. RENTAL ASSISTANCE, WHICH MAY BE SHORT-TERM, MEDIUM-TERM, OR LONG-TERM, AS WELL AS TENANT-BASED, PROJECT-BASED, OR SPONSOR-BASED, FOR TRANSITIONAL OR PERMANENT HOUSING; 3. SUPPORTIVE SERVICES TO ASSIST PROGRAM PARTICIPANTS OBTAIN AND MAINTAIN HOUSING; 4. OPERATING COSTS OF SUPPORTIVE HOUSING; 5. COSTS OF IMPLEMENTING AND OPERATING HMIS; 6. PROJECT ADMINISTRATIVE COSTS; 7. RELOCATION COSTS; AND 8. INDIRECT COSTS IN ACCORDANCE WITH 2 CFR PARTS 200, AS APPLICABLE. IN ADDITION TO USING GRANT FUNDS FOR THE ELIGIBLE COSTS DESCRIBED ABOVE, RECIPIENTS AND SUBRECIPIENTS IN CONTINUUMS OF CARE DESIGNATED AS HIGH PERFORMING COMMUNITIES MAY ALSO USE GRANT FUNDS TO PROVIDE HOUSING RELOCATION AND STABILIZATION SERVICES AND SHORT- AND/OR MEDIUM-TERM RENTAL ASSISTANCE TO YOUTH AT RISK OF HOMELESSNESS AS SET FORTH IN 24 CFR 576.103 AND 24 CFR 576.104, IF NECESSARY TO PREVENT YOUTH FROM BECOMING HOMELESS. NO ASSISTANCE PROVIDED UNDER PROGRAM (OR ANY STATE OR LOCAL GOVERNMENT FUNDS USED TO SUPPLEMENT THIS ASSISTANCE) MAY BE USED TO REPLACE STATE OR LOCAL FUNDS PREVIOUSLY USED, OR DESIGNATED FOR USE, TO ASSIST HOMELESS PERSONS OR PERSONS AT-RISK OF HOMELESSNESS.; EXPECTED OUTCOMES: DECREASE IN THE NUMBER OF YOUTH EXPERIENCING HOMELESSNESS, MORE SPECIFICALLY USING PERFORMANCE INDICATORS SUCH AS THE LENGTH OF TIME HOMELESS, RETURNS TO HOMELESSNESS OVER TIME, AND EXITS TO PERMANENT HOUSING. COC PERFORMANCE PROFILE REPORTS CAN BE FOUND AT: HTTPS://WWW.HUDEXCHANGE.INFO/PROGRAMS/COC/COC-PERFORMANCE-PROFILE-REPORTS/; INTENDED BENEFICIARIES: YOUTH DEFINED AS HOUSEHOLDS WHERE NO PERSON IS OVER THE AGE OF 24; SUBRECIPIENT ACTIVITIES: THE SUBRECIPIENT ACTIVITIES ARE UNKNOWN AT THE TIME OF AWARD

PROVIDING ALL ASPECTS OF THE BASIC CENTER PROGRAM FOR RUNAWAY,HOMELESS AND STREET YOUTH AND YOUTH AT-RISK OF SUCH IN MIDDLE TENNESSEE.

CONTINUUM OF CARE PROGRAM

CONTINUUM OF CARE PROGRAM

CONTINUUM OF CARE PROGRAM

PURPOSE: THE CONTINUUM OF CARE (COC) PROGRAM IS DESIGNED TO PROMOTE COMMUNITY-WIDE COMMITMENT TO THE GOAL OF ENDING HOMELESSNESS; PROVIDE FUNDING FOR EFFORTS BY NONPROFIT PROVIDERS, STATES, AND LOCAL GOVERNMENTS TO QUICKLY HOUSE HOMELESS INDIVIDUALS AND FAMILIES WHILE MINIMIZING THE TRAUMA AND DISLOCATION CAUSED TO HOMELESS INDIVIDUALS, FAMILIES, AND COMMUNITIES BY HOMELESSNESS; PROMOTE ACCESS TO AND EFFECTIVE UTILIZATION OF MAINSTREAM PROGRAMS BY HOMELESS INDIVIDUALS AND FAMILIES; AND OPTIMIZE SELF-SUFFICIENCY AMONG INDIVIDUALS AND FAMILIES EXPERIENCING HOMELESSNESS. THE MOST RECENT COC AWARD ANNOUNCEMENT LISTING AWARDS BY STATE AND COC IS ACCESSIBLE AT HTTPS://WWW.HUD.GOV/PROGRAM_OFFICES/COMM_PLANNING/COC/AWARDS. SELECT THE LINK UNDER THE FUNDING AND AWARD INFORMATION SECTION FOR THE APPROPRIATE FISCAL YEAR.; ACTIVITIES TO BE PERFORMED: CONTINUUM OF CARE PROGRAM FUNDS MAY BE USED TO PAY FOR THE ELIGIBLE COSTS USED TO ESTABLISH AND OPERATE PROJECTS UNDER FIVE PROGRAM COMPONENTS: (1) PERMANENT HOUSING, WHICH INCLUDES PERMANENT SUPPORTIVE HOUSING FOR PERSONS WITH DISABILITIES, AND RAPID REHOUSING; (2) TRANSITIONAL HOUSING; (3) SUPPORTIVE SERVICES ONLY; (4) HOMELESS MANAGEMENT INFORMATION SYSTEMS (HMIS), AND (5) IN SOME CASES, HOMELESSNESS PREVENTION. THIRTEEN TYPES OF ASSISTANCE MAY BE PROVIDED THROUGH THE CONTINUUM OF CARE (COC) PROGRAM: (1) COC PLANNING ACTIVITIES/COSTS FOR DESIGNING AND CARRYING OUT A COLLABORATIVE PROCESS FOR THE DEVELOPMENT OF AN APPLICATION TO HUD; (2) UNITED FUNDING AGENCY (UFA) COSTS FOR FISCAL CONTROL AND ACCOUNTING NECESSARY TO ASSURE THE PROPER DISBURSAL OF, AND ACCOUNTING FOR, FEDERAL FUNDS AWARDED TO SUBRECIPIENTS UNDER THE CONTINUUM OF CARE PROGRAM, (3) ACQUISITION OF REAL PROPERTY (INCLUDING STRUCTURES) FOR USE IN THE PROVISION OF HOUSING OR SUPPORTIVE SERVICES; (4) REHABILITATION OF STRUCTURES TO PROVIDE HOUSING OR SUPPORTIVE SERVICES; (5) NEW CONSTRUCTION, INCLUDING THE BUILDING OF A NEW STRUCTURE OR BUILDING AN ADDITION TO AN EXISTING STRUCTURE FOR USE AS SUPPORTIVE HOUSING; (6) LEASING OF A STRUCTURE OR STRUCTURES, OR PORTIONS THEREOF, TO PROVIDE HOUSING OR SUPPORTIVE SERVICES; (7) RENTAL ASSISTANCE, WHICH MAY BE SHORT-TERM, MEDIUM-TERM, OR LONG-TERM, AS WELL AS TENANT-BASED, PROJECT-BASED, OR SPONSOR-BASED, FOR TRANSITIONAL OR PERMANENT HOUSING; (8) SUPPORTIVE SERVICES TO ASSIST PROGRAM PARTICIPANTS OBTAIN AND MAINTAIN HOUSING; (9) OPERATING COSTS OF SUPPORTIVE HOUSING; (10) COSTS OF IMPLEMENTING AND OPERATING HMIS; (11) PROJECT ADMINISTRATIVE COSTS; (12) RELOCATION COSTS; AND (13) INDIRECT COSTS IN ACCORDANCE WITH 2 CFR PARTS 200, AS APPLICABLE. IN ADDITION TO USING GRANT FUNDS FOR THE ELIGIBLE COSTS DESCRIBED ABOVE, RECIPIENTS AND SUBRECIPIENTS IN CONTINUUMS OF CARE DESIGNATED AS HIGH PERFORMING COMMUNITIES MAY ALSO USE GRANT FUNDS TO PROVIDE HOUSING RELOCATION AND STABILIZATION SERVICES AND SHORT- AND/OR MEDIUM-TERM RENTAL ASSISTANCE TO INDIVIDUALS AND FAMILIES AT RISK OF HOMELESSNESS AS SET FORTH IN 24 CFR 576.103 AND 24 CFR 576.104, IF NECESSARY TO PREVENT THE INDIVIDUAL OR FAMILY FROM BECOMING HOMELESS. LIMITATION ON USE OF FUNDS: NO ASSISTANCE PROVIDED UNDER PROGRAM (OR ANY STATE OR LOCAL GOVERNMENT FUNDS USED TO SUPPLEMENT THIS ASSISTANCE) MAY BE USED TO REPLACE STATE OR LOCAL FUNDS PREVIOUSLY USED, OR DESIGNATED FOR USE, TO ASSIST HOMELESS PERSONS OR PERSONS AT-RISK OF HOMELESSNESS.; EXPECTED OUTCOMES: DECREASE IN THE NUMBER INDIVIDUALS AND FAMILIES EXPERIENCING HOMELESSNESS, MORE SPECIFICALLY USING PERFORMANCE INDICATORS SUCH AS THE LENGTH OF TIME HOMELESS, RETURNS TO HOMELESSNESS OVER TIME, AND EXITS TO PERMANENT HOUSING. COC PERFORMANCE PROFILE REPORTS CAN BE FOUND AT HTTPS://WWW.HUDEXCHANGE.INFO/PROGRAMS/COC/COC-PERFORMANCE-PROFILE-REPORTS/.; INTENDED BENEFICIARIES: INDIVIDUALS AND FAMILIES EXPERIENCING HOMELESSNESS.; SUBRECIPIENT ACTIVITIES: THE SUBRECIPIENT ACTIVITIES ARE UNKNOWN AT THE TIME OF AWARD.

PIERCE COUNTY BASIC CENTER PROGRAM (THE LOFT)

OASIS CENTER EMERGENCY SHELTER (BCP)

PROVIDING ALL ASPECTS OF THE BASIC CENTER PROGRAM FOR RUNAWAY,HOMELESS AND STREET YOUTH AND YOUTH AT-RISK OF SUCH IN MIDDLE TENNESSEE.

BASIC CENTER PROGRAM

THE GOAL OF THE PROJECT IS TOCOMPLEMENT AND EXPAND THE EXISTING MOMS & KIDS PROGRAM BY IMPROVING STEPPING STONES NETWORKS CAPABILITY AND CAPACITY TO PROVIDE RAPID REHOUSING. OUTCOMES TO INCLUDE ADDITION OF A HOUSING NAVIGATOR, NEW HOUSING PARTNERSHIPS, GROWTH IN NUMBER OF FAMILIES HOUSED, AND GROWTH IN NUMBER OF PROGRAM GRADUATES.

AN ESTIMATED 450 RSVP VOLUNTEERS WILL SERVE AS TUTORS IN PUBLIC SCHOOLS IN ST. LOUIS CITY, ST. LOUIS COUNTY, ST. CHARLES COUNTY AND JEFFERSON COUNTY. ALL 450 RSVP VOLUNTEERS WILL BE PLACED IN OUTCOME ASSIGNMENTS. BUILDING ON ITS PROVEN MODEL AND EXPERTISE IN ENGAGING OLDER ADULT VOLUNTEERS, OASIS WILL ADDRESS THE PRIMARY FOCUS AREA OF EDUCATION TO IMPROVE EDUCATIONAL OUTCOMES FOR ECONOMICALLY DISADVANTAGED AND ACADEMICALLY AT-RISK CHILDREN. TO MEET THIS NEED, OVER THE COURSE OF THREE YEARS, OASIS WILL RECRUIT, TRAIN, AND PLACE 450 UNDUPLICATED RSVP VOLUNTEERS WHO WILL SERVE DIRECTLY IN SCHOOLS (VOLUNTEER STATIONS) PROVIDING LITERACY TUTORING AND MENTORING SUPPORT TO 925 STUDENTS IN THE PROPOSED SERVICE AREA. THESE VOLUNTEERS WILL PROVIDE MORE THAN 36,000 HOURS OF SERVICE PER YEAR. OF THE STUDENTS SERVED BY YEAR THREE, 80 PERCENT OF THOSE STUDENTS (740) WILL SHOW IMPROVED ACADEMIC PERFORMANCE IN LITERACY AS MEASURED BY PRE- AND POST-TESTS. THE OASIS RSVP PROGRAM WILL MEET THE CRITICAL COMMUNITY NEED OF IMPROVING STUDENTS' ACADEMIC PERFORMANCE IN LITERACY WHILE STRENGTHENING SCHOOL COMMUNITIES THROUGH THE PRESENCE OF CARING, WELL-TRAINED, OLDER ADULT VOLUNTEERS. THE CNCS FEDERAL INVESTMENT OF $198,147 WILL BE SUPPLEMENTED BY $88,095 FROM FUNDING FROM CORPORATIONS AND FOUNDATION.

YOUTH OASIS BASIC CENTER PROGRAM

YOUTH OASIS TRANSITIONAL LIVING HOME FOR PREGNANT AND PARENTING YOUTH

BASIC CENTER PROGRAM

YOUTH OASIS EMERGENCY SHELTER AND DROP-IN CENTER

CONTINUUM OF CARE PROGRAM

CONTINUUM OF CARE PROGRAM

CONTINUUM OF CARE PROGRAM

MISSOURI FALLS PREVENTION INITIATIVE

REAP RENEWABLE ENERGY SYSTEM (RES) GRANT UNRESTRICTED AMOUNT

MISSOURI FALLS PREVENTION INITIATIVE

THE COFFEE OASIS - SERRA HOUSE

SBIR PHASE II: HIGH PERMEABILITY THIN-FILM NANOCOMPOSITE MEMBRANES FOR REVERSE OSMOSIS DESALINATION

AN ESTIMATED 375 RSVP VOLUNTEERS WILL SERVE. OF THIS NUMBER, 353 RSVP VOLUNTEERS WILL BE PLACED IN OUTCOME ASSIGNMENTS. THEIR ACTIVITIES WILL BE TUTORING IN PUBLIC SCHOOLS IN ST. LOUIS CITY, ST. LOUIS COUNTY AND ST. CHARLES COUNTY, RECRUITING VOLUNTEERS, AND COACHING CHILDREN IN K-3 GRADES HEALTHY LIFELONG HABITS. THE PRIMARY FOCUS AREA OF THIS PROJECT IS EDUCATION. AT THE END OF THE THREE-YEAR GRANT, OUT OF 706 K-3 STUDENTS, 413 WILL HAVE IMPROVED ACADEMIC PERFORMANCE AS MEASURED BY READING ASSESSMENTS USED BY THE INDIVIDUAL SCHOOL DISTRICTS SUCH AS FOUNTAS AND PINNELL, GATES MCGINITIE, OR IREADY DIAGNOSTIC. THE CNCS FEDERAL INVESTMENT OF $115,628 WILL BE SUPPLEMENTED BY $49,697 FROM FUNDING FROM CORPORATIONS AND FOUNDATIONS. THE OASIS INSTITUTE (OASIS), A 501 (C) (3) ORGANIZATION, IS PROPOSING TO CONTINUE A SENIOR CORPS RETIRED AND SENIOR VOLUNTEER PROGRAM (RSVP) IN ST. LOUIS CITY, ST. LOUIS COUNTY AND ST. CHARLES COUNTY IN MISSOURI. THE MISSION OF OASIS IS TO PROMOTE HEALTHY AGING THROUGH LIFELONG LEARNING, ACTIVE LIFESTYLES, AND VOLUNTEER ENGAGEMENT. THE OASIS ST. LOUIS RSVP PROGRAM WILL RECRUIT, TRAIN, AND PLACE 375 VOLUNTEERS WHO ARE 55 AND OLDER BY THE THIRD YEAR OF PROGRAM OPERATIONS. BUILDING ON ITS PROVEN MODEL AND EXPERTISE IN ENGAGING OLDER ADULT VOLUNTEERS, OASIS WILL ADDRESS THE PRIMARY FOCUS AREA OF EDUCATION TO IMPROVE EDUCATIONAL OUTCOMES FOR ECONOMICALLY DISADVANTAGED AND ACADEMICALLY AT-RISK CHILDREN. THERE IS CONSENSUS AMONG EDUCATION EXPERTS THAT IT IS CRITICALLY IMPORTANT FOR CHILDREN TO READ AT GRADE LEVEL BY THE END OF THIRD GRADE. RESEARCH HAS DEMONSTRATED THE CORRELATION BETWEEN A STUDENT'S READING ABILITY AT THIS POINT AND HIS OR HER SUBSEQUENT ACADEMIC SUCCESS. THOUSANDS OF STUDENTS IN MISSOURI INCLUDING STUDENTS IN THE SERVICE AREA OF THE OASIS ST. LOUIS RSVP PROGRAM FAIL TO MEET THIS BENCHMARK. ON THE ENGLISH/LANGUAGE ARTS PORTION OF THE 2016 MISSOURI ASSESSMENT PROGRAM (MAP), 57.8 PERCENT OF ALL THIRD GRADERS IN THE STATE FELL BELOW THE PROFICIENT LEVEL. THE OASIS ST. LOUIS RSVP PROGRAM WILL CONTINUE TO MEET THE CRITICAL COMMUNITY NEED OF IMPROVING STUDENTS' ACADEMIC PERFORMANCE IN LITERACY WHILE STRENGTHENING SCHOOL COMMUNITIES THROUGH THE PRESENCE OF CARING, WELL- TRAINED, OLDER ADULT VOLUNTEERS. TO MEET THIS NEED, OVER THE COURSE OF THREE YEARS, OASIS WILL RECRUIT, TRAIN, AND PLACE AT LEAST 375 UNDUPLICATED RSVP VOLUNTEERS WITH 353 SERVING DIRECTLY IN SCHOOLS (VOLUNTEER STATIONS) PROVIDING LITERACY TUTORING AND SUPPORT TO 706 STUDENTS. OF THE STUDENTS BEING SERVED BY YEAR THREE, 90% OR 635 STUDENTS WILL COMPLETE THE PROGRAM AND 65% OF STUDENTS OR 413 STUDENTS WILL SHOW IMPROVED ACADEMIC PERFORMANCE IN LITERACY AS MEASURED BY PRE- AND POST-TESTS. OVER THE THREE-YEAR GRANT PERIOD, UNDUPLICATED VOLUNTEERS WILL PROVIDE MORE THAN 30,091 HOURS OF SERVICE.

PROVIDING ALL ASPECTS OF THE STREET OUTREACH PROGRAM FOR RUNAWAY,HOMELESS AND STREET YOUTH AND YOUTH AT-RISK OF HOMELESSNESS IN MIDDLE TENNESSEE.

STREET OUTREACH PROGRAM

COMPASSION CAPITAL FUND (CCF) COMMUNITIES EMPOWERING YOUTH PROGRAM

PURPOSE: ECONOMIC DEVELOPMENT INITIATIVE, COMMUNITY PROJECT FUNDING/CONGRESSIONAL DIRECTED SPENDING AWARDS ARE AUTHORIZED UNDER THE CONSOLIDATED APPROPRIATIONS ACT, 2022 PUBLIC LAW 117-328 AND THE EXPLANATORY STATEMENT FOR DIVISION L OF THAT ACT. PROJECTS SELECTED FOR COMMUNITY PROJECT FUNDING/CONGRESSIONAL DIRECTED SPENDING ARE LISTED IN THE JOINT EXPLANATORY STATEMENT (JES) THAT ACCOMPANIES A SPECIFIC FISCAL YEAR’S APPROPRIATIONS ACT OR CONGRESSIONAL RECORD. THE JES LISTS PROJECT, RECIPIENT, STATE, AMOUNT AND CONGRESSIONAL SPONSOR.; ACTIVITIES TO BE PERFORMED: ECONOMIC DEVELOPMENT INITIATIVE, COMMUNITY PROJECT FUNDING/CONGRESSIONALLY DIRECTED SPENDING AWARD PROJECTS INCLUDE A WIDE VARIETY OF ACTIVITIES THAT RESULT IN ECONOMIC DEVELOPMENT OR COMMUNITY DEVELOPMENT OUTCOMES. HUD WILL NOT KNOW THE FULL SCOPE OF THE PROJECT UNTIL THE RECIPIENT SUBMITS THE REQUIRED PROJECT NARRATIVE AND CONFIRMS ALIGNMENT WITH THE LANGUAGE AS PROVIDED IN THE CONGRESSIONAL RECORD. TO FIND THE DETAILS OF THE GRANT AWARD AS WRITTEN WITHIN THE CONGRESSIONAL RECORD USE THE FOLLOWING LINK AND PATH SELECTIONS TO GET TO THE DESCRIPTION OF THE ECONOMIC DEVELOPMENT INITIATIVE, COMMUNITY PROJECT FUNDING GRANTS HTTPS://WWW.HUD.GOV/PROGRAM_OFFICES/COMM_PLANNING/EDI-GRANTS, SELECT THE FISCAL YEAR OF INTEREST, SCROLL DOWN TO PROGRAM LAWS AND REGULATIONS, UNDER FISCAL YEAR 20XX CONSOLIDATED APPROPRIATIONS ACT, 20XX: CONGRESSIONAL RECORD (JOINT EXPLANATORY STATEMENT).; EXPECTED OUTCOMES: COMPLETION OF THE PROJECT AS DESCRIBED IN THE JOINT EXPLANATORY STATEMENT (JES) PROJECT DESCRIPTION AND SUBSEQUENT APPROVED PROJECT NARRATIVE.; INTENDED BENEFICIARIES: THE PROJECT BENEFICIARIES ARE THE INDIVIDUALS AND/OR ORGANIZATIONS THAT ARE AWARDED GRANT FUNDS OR SERVED BY THE ENTITIES THAT ARE AWARDED GRANT FUNDS AS IDENTIFIED IN THE JES RECIPIENT OR PROJECT DESCRIPTION SECTIONS.; SUBRECIPIENT ACTIVITIES: THE SUBRECIPIENT ACTIVITIES ARE UNKNOWN AT THE TIME OF AWARD.

DEVELOPMENT OF PAR2 PEPDUCINS FOR THE TREATMENT OF COPD - CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD), WHICH INCLUDES CHRONIC BRONCHITIS AND EMPHYSEMA, AFFLICTS 16 MILLION AMERICANS AND IS THE THIRD LEADING CAUSE OF DISEASE-RELATED DEATH IN THE US. THE STANDARD-OF-CARE TREATMENT FOR COPD LUNG DISEASE IS TYPICALLY SYMPTOMATIC RELIEF WITH BRONCHODILATOR THERAPY. AS LEUKOCYTE INFILTRATION IS THE CRUX OF THE DISEASE, PATIENTS ARE ALSO TREATED WITH ANTI-INFLAMMATORY DRUGS THAT SUPPRESS TISSUE DAMAGE AND CYTOKINE RELEASE. HOWEVER, MAJOR CHALLENGES REMAIN WITH USE OF IMMUNOSUPPRESSANTS WHICH INCREASE THE RISK OF PNEUMONIA AND OTHER SIDE EFFECTS, AND GENERALLY LEAVE THE PATIENT WITH A POOR QUALITY OF LIFE WITH DIMINISHING LUNG FUNCTION, NOT TO MENTION HIGH COST. THEREFORE, NEW DISEASE-MODIFYING TREATMENT OPTIONS ARE IN GREAT DEMAND FOR COPD PATIENTS. OASIS PHARMACEUTICALS AND THEIR COLLABORATORS AT TUFTS MEDICAL CENTER HAVE FOCUSED THEIR EFFORTS ON A NOVEL TARGET—PROTEASE-ACTIVATED RECEPTOR-2 (PAR2), RECENTLY DISCOVERED AS AN IMPORTANT MEDIATOR IN THE PATHOGENESIS OF COPD. PAR2 IS A MAJOR CELL SURFACE RECEPTOR FOR ELASTASE AND OTHER PROTEASES THAT ARE UPREGULATED IN LUNG BRONCHIAL AND ALVEOLAR EPITHELIAL CELLS, MUCUS-PRODUCING GOBLET CELLS, AND INFLAMMATORY CELLS DURING PROGRESSION OF COPD. THE CELL-PENETRATING, LIPIDATED PAR2 INHIBITOR OA-235I, WAS DEVELOPED USING OUR PROPRIETARY PEPDUCINTM TECHNOLOGY. PEPDUCINTM TECHNOLOGY OFFERS A UNIQUE OPPORTUNITY TO TARGET THE INTRACELLULAR SURFACE OF RECALCITRANT G-PROTEIN COUPLED RECEPTORS (GPCRS) SUCH AS PAR2 WITH EXQUISITE SPECIFICITY, POTENCY AND LONG HALF-LIVES, WITH PROLONGED DRUG EXPOSURE TO THE TARGET TISSUE, NAMELY LUNG. OA-235I IS AN ADVANCED DRUG CANDIDATE THAT BLOCKS DAMAGING PAR2 SIGNALING IN PRECLINICAL MODELS OF COPD. OASIS PHARMACEUTICALS SUCCESSFULLY FORMULATED AND PRODUCED CGMP OA-235I AT 98% PURITY AND HIGH STABILITY. IN PILOT IN VIVO EFFICACY STUDIES, OA-235I SIGNIFICANTLY REDUCED EMPHYSEMA AND INFLAMMATION IN ELASTASE-COPD MODELS BY ≥50%. OA-235I WAS SAFE AND TOLERATED IN 28-DAY REPEAT DOSE GLP TOXICOLOGY STUDIES IN TWO SPECIES WITH NO EVIDENCE OF ORGAN TOXICITY OR ANY LABORATORY ABNORMALITIES AT HIGH MULTIPLES OF THE THERAPEUTIC DOSE. PHASE I WILL VALIDATE THE THERAPEUTIC POTENTIAL OF DAILY THROUGH ONCE-WEEKLY OA-235I IN COPD MODELS AND IN TISSUE CULTURE AND CHARACTERIZE PAR2 INFLAMMATORY RESPONSES IN PRIMARY TISSUES FROM COPD PATIENTS AND HEALTHY CONTROLS. THE FINAL MILESTONE WILL BE TO CONDUCT A PREIND MEETING TO DESIGN A FIRST-IN- COPD PATIENT CLINICAL TRIAL OF REPEAT DOSE OA-235I WITH THE FDA DIVISION OF PULMONARY, ALLERGY AND CRITICAL CARE (DPACC). THE TRANSLATIONAL STUDIES IN THIS APPLICATION WILL THEREFORE PROVIDE A RAPID PRECLINICAL VALIDATION AND ACCELERATE THE COMMERCIALIZATION OF OA-235I FOR THE TREATMENT OF COPD PATIENTS.

PROVIDING ALL ASPECTS OF THE STREET OUTREACH PROGRAM FOR RUNAWAY,HOMELESS AND STREET YOUTH AND YOUTH AT-RISK OF HOMELESSNESS IN MIDDLE TENNESSEE.

OASIS CENTER, INC.'S STREET OUTREACH PROGRAM

THE STEPPING STONES NETWORK MOMS & KIDS PROGRAM PROVIDES LONG-TERM WRAP AROUND SERVICES FOR SEX TRAFFICKING VICTIMS WHO ARE MOTHERS WITH CHILDREN IN CHICAGO, IL AND SURROUNDING AREAS. SERVICES TREAT BOTH MOTHER AND CHILD AS CLIENT IN FACILITATING THEIR ROAD TO RECOVERY WHILE PROTECTING THEM FROM ADDITIONAL EXPLOITATION. THE GOAL OF THE PROPOSED PROJECT IS TO STRENGTHEN AND EXPAND THE STEPPING STONES NETWORK MOMS & KIDS PROGRAM TO INCREASE THE IMPACT OF THE EXISTING LONG-TERM PROGRAM AND PRODUCE GRADUATES. OBJECTIVES FOR THE PROJECT INCLUDE PROGRAM GRADUATES WHO ARE: (A) LIVING INDEPENDENTLY IN A SAFE ENVIRONMENT AND MAINTAINING A SAFE CIRCLE OF SUPPORT, (B) ESTABLISHING ECONOMIC INDEPENDENCE VIA PURSUING WORK OR EDUCATION CONSISTENTLY, (C) REMAINING FREE FROM THE CYCLE OF EXPLOITATION, (D) CHILDREN’S ACE (ADVERSE CHILDHOOD EXPERIENCES) SCORES ARE LOWER THAN THE SCORES OF THEIR PARENT(S), AND (E) BASK (BEHAVIORS, ATTITUDES, SKILLS & KNOWLEDGE) SCORES MEASURE AND SHOW IMPROVEMENT IN LIFE SKILLS, HOLISTIC HEALTH, HOME MANAGEMENT, PARENTING, RELATIONSHIPS, TRAUMA RESOLUTION AND ADDICTION RECOVERY. PER PRIORITY CONSIDERATION A, GRANT FUNDED ACTIVITIES WILL PROVIDE HIGHER PRIORITY ACCESS FOR BLACK WOMEN AND CHILDREN ADVERSELY AFFECTED BY INEQUALITY AND LACK OF STABLE FAMILY SYSTEMS. PARTICIPANTS WILL BE (1) LIVING AWAY FROM HIGH VIOLENCE LOCATIONS IN A SAFER ENVIRONMENT; (2) PROVIDED STABLE, FULL OR PARTIALLY SUBSIDIZED INDEPENDENT HOUSING FOR UP TO 24 MONTHS NEAR THE SSN ADULT & CHILD DEVELOPMENT CENTER; (3) PROVIDED CONSISTENT, DAILY FACE-TO-FACE SERVICES FOR BOTH ADULTS AND CHILDREN TO DEVELOP LIFE SKILLS, BREAK THE CYCLE OF TRAUMA, AND BE PROVIDED WITH ECONOMIC OPPORTUNITY; AND (4) MAINTAINING AND EXPANDING A SAFE CIRCLE OF SUPPORT AND A SENSE OF COMMUNITY, WHILE HELPING ONE ANOTHER THROUGH SURVIVOR-LED MENTORSHIP.

BASIC CENTER PROGRAM

AN ESTIMATED 83 RSVP VOLUNTEERS WILL SERVE AS TUTORS IN PUBLIC SCHOOLS IN THE FULTON 58 SCHOOL DISTRICT, NORTH CALLAWAY R-1, SOUTH CALLAWAY R-2, PILOT GROVE C-IV AND NEW BLOOMFIELD R-3 SCHOOL DISTRICTS. ALL 83 RSVP VOLUNTEERS WILL BE PLACED IN OUTCOME ASSIGNMENTS. BUILDING ON ITS PROVEN MODEL AND EXPERTISE IN ENGAGING OLDER ADULT VOLUNTEERS, OASIS WILL ADDRESS THE PRIMARY FOCUS AREA OF EDUCATION TO IMPROVE EDUCATIONAL OUTCOMES FOR ECONOMICALLY DISADVANTAGED AND ACADEMICALLY AT-RISK CHILDREN. TO MEET THIS NEED, OVER THE COURSE OF THREE YEARS, OASIS WILL RECRUIT, TRAIN, AND PLACE 83 UNDUPLICATED RSVP VOLUNTEERS WHO WILL SERVE DIRECTLY IN SCHOOLS (VOLUNTEER STATIONS) PROVIDING LITERACY TUTORING AND MENTORING SUPPORT TO 150 STUDENTS IN THE PROPOSED SERVICE AREA. THESE VOLUNTEERS WILL PROVIDE MORE THAN 6,640 HOURS OF SERVICE PER SCHOOL YEAR. OF THE STUDENTS SERVED BY YEAR THREE, 150 STUDENTS WILL COMPLETE THE PROGRAM AND 80 PERCENT OF THOSE STUDENTS (120) WILL SHOW IMPROVED ACADEMIC PERFORMANCE IN LITERACY AS MEASURED BY PRE-AND POST READING TESTS. CALLAWAY COUNTY RSVP PROGRAM WILL MEET THE CRITICAL COMMUNITY NEED OF IMPROVING STUDENTS' ACADEMIC PERFORMANCE IN LITERACY WHILE STRENGTHENING SCHOOL COMMUNITIES THROUGH THE PRESENCE OF CARING, WELL-TRAINED, OLDER ADULT VOLUNTEERS. THE CNCS FEDERAL INVESTMENT OF $82,500 WILL BE SUPPLEMENTED BY $9,575 FROM FUNDING FROM CORPORATIONS AND FOUNDATIONS.

BASIC CENTER PROGRAM

DEVELOPMENT OF LIVER HOMING PAR2 PEPDUCINS FOR THE TREATMENT OF HEPATOCELLULAR CARCINOMA - HEPATOCELLULAR CARCINOMA (HCC) HAS BECOME THE SECOND LEADING CAUSE OF CANCER-RELATED DEATH IN THE WORLD, WITH A 72% MORTALITY RATE IN THE US. THE RISE IN INCIDENCE OF HCC IS DUE TO A STEADY INCREASE IN THE MAJOR RISK FACTORS OF LIVER FIBROSIS, CIRRHOSIS, AND HEPATITIS B/C, WITH LIMITED EFFICACY CONFERRED BY EXISTING TREATMENTS AT ADVANCED STAGES OF THE DISEASE. SYSTEMIC THERAPY WITH TYROSINE KINASE INHIBITORS, MOST NOTABLY SORAFENIB, IS NOW RECOMMENDED BY MOST GUIDELINES FOR THOSE PATIENTS NOT ELIGIBLE FOR LIVER RESECTION. THE VAST MAJORITY OF HCCS OCCUR WITH UNDERLYING HEPATIC DAMAGE (CHARACTERIZED BY PATHOLOGICAL VASCULAR, INFLAMMATORY AND PRO- FIBROTIC RESPONSES); AND A HIGHLY ABNORMAL TUMOR MICROENVIRONMENT (TME) WITH EXUBERANT ANGIOGENESIS, IMMUNOSUPPRESSION, AND FIBROSIS. SORAFENIB MONOTHERAPY DOES NOT EFFECTIVELY OVERCOME THESE ABNORMALITIES IN THE DAMAGED LIVER AND THE TME. ACCORDINGLY, THERE REMAINS A HIGH UNMET MEDICAL NEED FOR NEW APPROACHES FOR THE TREATMENT OF HCC. AN EMERGING NEW TARGET IN HCC IS THE G PROTEIN-COUPLED, PROTEASE-ACTIVATED RECEPTOR 2 (PAR2). PAR2 IS A SIGNALING RECEPTOR FOR COAGULATION AND TUMOR-ASSOCIATED PROTEASES THAT IS HIGHLY ABUNDANT IN VARIOUS LIVER CELLS (HEPATOCYTES, ENDOTHELIUM, STELLATE CELLS, INFLAMMATORY CELLS) WHICH CONTROLS FIBROTIC, INFLAMMATORY AND METABOLIC PROCESSES THAT LEAD TOWARDS SEVERE NASH, LIVER CIRRHOSIS AND HCC. PAR2 EXPRESSION IN HCC TUMORS IS SIGNIFICANTLY CORRELATED WITH POOR SURVIVAL, POOR DIFFERENTIATION AND ADVANCED TUMOR-NODE-METASTASIS STAGE. WE FOUND THAT HEPATIC PAR2 EXPRESSION WAS GREATLY ENHANCED IN PATIENTS (N=108) WITH HIGH LEVELS OF LIVER FIBROSIS AND CIRRHOSIS. IN ADDITION TO BEING INVOLVED IN FIBROSIS AND INFLAMMATION, PAR2 ACTIVATES A NUMBER OF HEPATIC CANCER PROMOTING PATHWAYS INCLUDING GI-PI3K, TGFB, PHOSPHO-AKT AND RAF-MAPK SIGNALING TO STIMULATE CANCER CELL MIGRATION/INVASION, EMT, METASTASIS, ANTI-APOPTOTIC SURVIVAL, PROLIFERATION, ANGIOGENESIS, AND PROMOTION OF A PERMISSIVE TUMOR MICROENVIRONMENT. PILOT DATA INDICATE THAT PAR2 PEPDUCIN TREATMENT MAY POTENTIALLY SUPPRESS HCC TUMOR DEVELOPMENT THAT WILL BE VALIDATED IN DETAIL USING IN VITRO AND IN VIVO HEPATOCELLULAR MOUSE MODELS OF TUMOR GROWTH AND SURVIVAL. AIMS 1 AND 2 OUTLINE BRIDGING STUDIES AS A COLLABORATIVE EFFORT BETWEEN OASIS PHARMACEUTICALS (LEXINGTON, MA) AND TUFTS (BOSTON, MA) THAT WOULD PROVIDE KEY FEASIBILITY MILESTONES TO ADVANCE THE CLINICAL DEVELOPMENT OF PAR2 PEPDUCIN INTO THE HCC INDICATION. THE MAJOR MILESTONES AT THE END OF THE 6 MONTHS IS EFFICACY IN HCC MOUSE MODELS (SIGNIFICANT SUPPRESSION OF TUMOR GROWTH AND IMPROVED SURVIVAL) (AIM 1), AND 28-DAY SAFETY/TOXICITY ASSESSMENTS (>10-FOLD THERAPEUTIC SAFETY INDEX) OF COMBINATION THERAPY WITH SORAFENIB (AIM 2). IF THIS PHASE I STTR STUDY IS SUCCESSFUL IN ACCOMPLISHING THE OUTLINED EFFICACY AND SAFETY MILESTONES, THIS WOULD PROVIDE THE BASIS FOR A PREIND MEETING WITH THE FDA, IND SUBMISSION, AND INITIATING A PHASE 1 CLINICAL TRIAL IN HCC PATIENTS.

REAP IRA RES GRANT UNRESTRICTED (FY 25)

PIERCE COUNTY STREET OUTREACH PROGRAM

DEVELOPMENT OF PAR4 PEPDUCINS AS A NOVEL ANTITHROMBOTIC TREATMENT

LIPID RECEPTOR GPR31 AS A TARGET FOR ANTI-THROMBOTIC AND STROKE THERAPY - DESPITE PREVALENT USE OF ANTI-PLATELET AND ANTI-LIPID THERAPIES, STROKE REMAINS THE THIRD MAJOR CAUSE OF DEATH AND IS THE LEADING CAUSE OF ADULT DISABILITY IN THE US WITH AN ESTIMATED COST IN THE RANGE OF $34 BILLION ANNUALLY. APPROXIMATELY 20% OF THE ANNUAL 795,000 STROKE PATIENTS DIE WITHIN ONE YEAR AND 15-30% ARE PERMANENTLY DISABLED. ANTIPLATELET THERAPY IS MAINLY USED FOR PRIMARY PREVENTION OF ACUTE ISCHEMIC STROKE IN CEREBROVASCULAR DISEASE. BIOACTIVE FATTY ACIDS ARE A NEW CLASS OF MOLECULAR TARGETS THAT HOLD GREAT THERAPEUTIC POTENTIAL BECAUSE OF THEIR DIVERSE ROLE AS SIGNALING MOLECULES THAT REGULATE METABOLISM AND INFLAMMATION. THE OXIDATION OF ARACHIDONIC ACID BY 12-LOX RESULTS IN THE PRODUCTION OF A NUMBER OF BIOACTIVE LIPIDS INCLUDING THE METABOLITE 12(S)-HETE. THE LIPID RECEPTOR GPR31, AN ORPHAN CLASS A GPCR, IS A 12(S)- HETE RECEPTOR RECENTLY SHOWN TO BE INVOLVED IN INFLAMMATORY SIGNALING. WE RECENTLY DISCOVERED THAT GPR31 MEDIATES 12(S)-HETE PROTHROMBOTIC SIGNALING IN PLATELETS AND PROMOTES GLUTAMATE-INDUCED OXIDATIVE TOXICITY NEURONAL CELLS. THEREFORE, WE PROPOSE THAT TARGETING GPR31 MAY PROVIDE A THERAPEUTIC PATH TOWARDS DEVELOPMENT OF A SAFE AND EFFECTIVE ANTIPLATELET THERAPY THAT IS COUPLED WITH SECONDARY NEUROPROTECTIVE EFFECTS FOR MITIGATING AGAINST THE ACUTE NEUROLOGIC SEQUELA OF STROKE TO PROVIDE A MORE EFFECTIVE AND SAFER ALTERNATIVE OPTION OR ADJUNCT TO FIBRINOLYTIC THERAPY. WE HAVE RECENTLY SUCCEEDED IN IDENTIFYING THE FIRST EFFECTIVE GPR31 ANTAGONIST USING OUR CELL-PENETRATING, MEMBRANE-TETHERED, PEPDUCIN TECHNOLOGY TO BE VALIDATED IN THESE PRECLINICAL FEASIBILITY STUDIES AS AN ANTI-PLATELET AND ANTI-STROKE AGENT. WE SHOW HERE THAT THIS I3-LOOP DERIVED GPR31 LIPOPEPTIDE HAS POTENT ANTIPLATELET ACTIVITY AND NEARLY COMPLETELY SUPPRESSES ARTERIAL THROMBOSIS WITHOUT AN EFFECT ON HEMOSTASIS IN MICE. PRELIMINARY DATA WITH THE GPR310 PEPDUCIN INDICATES A SIGNIFICANT REDUCTION IN ATHEROSCLEROTIC LESION BURDEN IN APOE-/- MICE. FURTHERMORE, WE PROVIDE EVIDENCE FOR A DIRECT NEUROPROTECTIVE EFFECT OF THE GPR310 PEPDUCIN ON HT22 NEURONAL CELLS SUBJECTED TO GLUTAMATE MEDIATED OXIDATIVE STRESS. THE GOAL OF THIS PHASE I STTR PROJECT IS TO DEVELOP THE GPR310 PEPDUCIN AS A COLLABORATIVE EFFORT BETWEEN OASIS PHARMACEUTICALS (LEXINGTON, MA), TUFTS MEDICAL CENTER (BOSTON, MA) AND ARONORA (PORTLAND, OR) THAT WOULD PROVIDE KEY EARLY MILESTONES TO ADVANCE THE INITIAL COMMERCIAL DEVELOPMENT OF THE FIRST GPR31 INHIBITOR AS A DUAL ANTIPLATELET, ANTI-STROKE DRUG. THIS FEASIBILITY STUDY WOULD ESTABLISH THE SCIENTIFIC MERIT OF THE PROPOSED PROGRAM BY ACCOMPLISHING THE MAJOR MILESTONES AT THE END OF THE 6 MONTHS OF SAFETY AND EFFICACY IN A STROKE MODEL AND PK/PD CORRELATIONS IN TWO SPECIES.

ENGAGES PERSONS 55 AND OLDER IN VOLUNTEER SERVICE IN THEIR COMMUNITIES

OASIS CENTER'S BASIC CENTER PROGRAM PROVIDES EMERGENCY SHELTER, COUNSELING SERVICES, AND COMPREHENSIVE SUPPORT TO ELIGIBLE RUNAWAY AND HOMELESS YOUTH UNDER THE AGE OF 18. - THE BASIC CENTER PROGRAM (BCP) (CY) PROVIDES TEMPORARY SHELTER AND COUNSELING SERVICES TO YOUTH WHO HAVE LEFT HOME WITHOUT PERMISSION OF THEIR PARENTS OR GUARDIANS, HAVE BEEN FORCED TO LEAVE HOME, OR OTHER HOMELESS YOUTH WHO MIGHT OTHERWISE END UP IN THE LAW ENFORCEMENT OR IN THE CHILD WELFARE, MENTAL HEALTH, OR JUVENILE JUSTICE SYSTEMS. BCPS WORK TO ESTABLISH OR STRENGTHEN COMMUNITY-BASED PROGRAMS THAT MEET THE IMMEDIATE NEEDS OF RUNAWAY AND HOMELESS YOUTH AND THEIR FAMILIES. BCPS PROVIDE YOUTH UNDER 18 YEARS OF AGE WITH EMERGENCY SHELTER, FOOD, CLOTHING, COUNSELING AND REFERRALS FOR HEALTH CARE. BCPS CAN PROVIDE UP TO 21 DAYS OF SHELTER FOR YOUTH AND SEEK TO REUNITE YOUNG PEOPLE WITH THEIR FAMILIES, WHENEVER POSSIBLE, OR TO LOCATE APPROPRIATE ALTERNATIVE PLACEMENTS.

YOUTH HOMELESSNESS DEMONSTRATION PROGRAM

AN ESTIMATED 83 RSVP VOLUNTEERS WILL SERVE AS TUTORS IN PUBLIC SCHOOLS IN CHILLICOTHE R-2, LIVINGSTON COUNTY R-3 AND SOUTHWEST LIVINGSTON COUNTY R-1 SCHOOL DISTRICTS. ALL 83 RSVP VOLUNTEERS WILL BE PLACED IN OUTCOME ASSIGNMENTS. BUILDING ON ITS PROVEN MODEL AND EXPERTISE IN ENGAGING OLDER ADULT VOLUNTEERS, OASIS WILL ADDRESS THE PRIMARY FOCUS AREA OF EDUCATION TO IMPROVE EDUCATIONAL OUTCOMES FOR ECONOMICALLY DISADVANTAGED AND ACADEMICALLY AT-RISK CHILDREN. TO MEET THIS NEED, OVER THE COURSE OF THREE YEARS, OASIS WILL RECRUIT, TRAIN, AND PLACE 83 UNDUPLICATED RSVP VOLUNTEERS WHO WILL SERVE DIRECTLY IN SCHOOLS (VOLUNTEER STATIONS) PROVIDING LITERACY TUTORING AND MENTORING SUPPORT TO 166 STUDENTS IN THE PROPOSED SERVICE AREA. THESE VOLUNTEERS WILL PROVIDE MORE THAN 6,640 HOURS OF SERVICE PER SCHOOL YEAR. OF THE STUDENTS SERVED BY YEAR THREE, 150 STUDENTS WILL COMPLETE THE PROGRAM AND 80 PERCENT OF THOSE STUDENTS (120) WILL SHOW IMPROVED ACADEMIC PERFORMANCE IN LITERACY AS MEASURED BY PRE-AND POST READING TESTS. LIVINGSTON COUNTY RSVP PROGRAM WILL MEET THE CRITICAL COMMUNITY NEED OF IMPROVING STUDENTS' ACADEMIC PERFORMANCE IN LITERACY WHILE STRENGTHENING SCHOOL COMMUNITIES THROUGH THE PRESENCE OF CARING, WELL-TRAINED, OLDER ADULT VOLUNTEERS. THE CNCS FEDERAL INVESTMENT OF $82,500 WILL BE SUPPLEMENTED BY $9,575 FROM FUNDING FROM CORPORATIONS AND FOUNDATION.

VEROFY: A NEW TOOL TO IMPROVE PRODUCTIVITY AND REDUCE COSTS FOR STRESS RESEARCH

HOMELESS ASSISTANCE

IMPACT AID SCHOOL CONSTRUCTION FORMULA GRANTS RECOVERY ACT

COMMUNITY PROJECT FUNDING/CONGRESSIONALLY DIRECTED SPENDING - CONSTRUCTION - PROJECT ABSTRACT: OASIS CENTER OF THE ROGUE VALLEY, IS A NONPROFIT MEDICAL CLINIC LOCATED IN MEDFORD OREGON, PROVIDING INTEGRATED SOCIAL AND MEDICAL SERVICES TO SUPPORT PARENTS WITH SUBSTANCE ABUSE DISORDERS AND THEIR YOUNG CHILDREN, AS WELL AS PREGNANT WOMEN WITH SUBSTANCE USE DISORDERS. THE OASIS CENTER WAS FOUNDED IN 2019 AS AN INNOVATIVE PROGRAM TO MEET THE UNIQUE NEEDS OF HIGH-RISK POPULATIONS: APPROXIMATELY ONE-THIRD OF OASIS PATIENTS HAVE CRIMINAL JUSTICE AND/OR CHILD WELFARE INVOLVEMENT, APPROXIMATELY 95% LIVE IN POVERTY, AND ALL OASIS ADULTS ARE AFFECTED BY SUBSTANCE USE DISORDERS, AND ALL OASIS CHILDREN HAVE A PARENT AFFECTED BY SUBSTANCE USE DISORDERS AND A MAJORITY WERE SUBSTANCE EXPOSED IN UTERO. THE SERVICES PROVIDED BY THE OASIS CENTER INCLUDE PRENATAL CARE, PEDIATRIC CARE, PRIMARY CARE, MEDICATION ASSISTED TREATMENT FOR OPIOID USE DISORDER, PEER SUPPORT, IMMUNIZATIONS, WOMEN’S HEALTH CARE, BEHAVIORAL HEALTH, CHILD WATCH, AND OTHER FAMILY SUPPORT SERVICES. THE OASIS CENTER IS ALSO DEVELOPING EMERGENCY HOUSING TO SHELTER UNHOUSED AND UNSAFELY HOUSED PREGNANT WOMEN WITH SUBSTANCE USE DISORDERS ON THE WAITLIST FOR RESIDENTIAL. THE RAPID GROWTH OF OASIS NECESSITATED A RELOCATION, AND THIS PROPOSED PROJECT INVOLVES THE RENOVATION AND IMPROVEMENTS TO THREE EXISTING BUILDINGS TO DEVELOP A COHESIVE MULTI-BUILDING FAMILY-CENTERED CAMPUS WHICH WILL SUPPORT FAMILIES IMPACTED BY SUBSTANCE USE DISORDERS, AS WELL AS IMPROVE A BLIGHTED NEIGHBORHOOD. OASIS HAS SECURED FUNDING FOR THE THREE BUILDINGS AND COMPLETED A PHASE 1 RENOVATION OF THE CLINIC TO BUILD EXAM ROOMS, AND A PHASE 1 RENOVATION OF THE EMERGENCY LODGING APARTMENTS TO SHELTER UNHOUSED AND UNSAFELY HOUSED PREGNANT WOMEN IN NEED OF RESIDENTIAL SUBSTANCE USE DISORDER TREATMENT. THERE IS STILL A SIGNIFICANT AMOUNT OF WORK NEEDED TO COMPLETE THE OASIS CAMPUS. THIS GRANT FUNDING REQUEST INCLUDES ARCHITECTURE AND RENOVATION COSTS TO IMPROVE THE INTERIOR AND EXTERIOR OF THE EXISTING BUILD INGS – ACTIVITIES OF THIS PROJECT WILL ADD OFFICE SPACE, IMPROVE AND EXPAND SERVICE DELIVERY AREAS, REPLACE WINDOWS, REPAIR SIDING AND THE ROOF, PAVE THE PARKING LOT, CREATE A WALKWAY FROM THE EMERGENCY HOUSING TO THE CLINIC, BEAUTIFY THE AREAS WITH LANDSCAPING, AND CREATE TWO ADA BATHROOMS. THE ENTIRE CAMPUS WILL BE PAINTED TO UNIFY THE BUILDINGS INTO ONE CAMPUS. THIS CLINIC IS A COMMUNITY RESOURCE FOR A HIGH-RISK POPULATION AND SERVES FAMILIES IN NEED. THE INVESTMENT IN THE UNIQUE SERVICES OF OASIS IMPROVES THE LIVES OF FAMILIES TODAY, AND IN THE FUTURE.

STREET OUTREACH PROGRAM

RECOVERY ACT - HIGH FLUX ULTRA LOW PRESSURE BWRO NANOCOMPOSITE MEMBRANE

REAL-TIME SALIVARY TESTOSTERONE AND EXTENSION TO MOBILE APPLICATION AND MULTIPLE BIOMARKER QUANTIFICATION CAPABILITY

AN ESTIMATED 75 RSVP VOLUNTEERS WILL SERVE AS TUTORS IN PUBLIC SCHOOLS IN EAST ST. LOUIS, CAHOKIA, AND BROOKLYN SCHOOL DISTRICTS. THE PRIMARY FOCUS AREA OF THIS PROJECT IS EDUCATION. AT THE END OF THE THREE-YEAR GRANT, 150 OUT OF 255 K-3 STUDENTS WILL HAVE IMPROVED ACADEMIC PERFORMANCE AS MEASURED BY READING ASSESSMENTS USED BY THE INDIVIDUAL SCHOOL DISTRICTS SUCH AS FOUNTAS AND PINNELL, GATES MCGINITIE, OR IREADY DIAGNOSTIC. THE CNCS FEDERAL INVESTMENT OF $75,000 WILL BE SUPPLEMENTED BY $13,753 FROM FUNDING FROM CORPORATIONS AND FOUNDATIONS. THE OASIS INSTITUTE (OASIS), A 501 (C) (3) ORGANIZATION, IS PROPOSING TO IMPLEMENT A SENIOR CORPS RETIRED AND SENIOR VOLUNTEER PROGRAM (RSVP) IN SOUTHERN ILLINOIS, SPECIFICALLY EAST ST. LOUIS, CAHOKIA AND BROOKLYN SCHOOL DISTRICTS (IL-1X). THE MISSION OF OASIS IS TO PROMOTE HEALTHY AGING THROUGH LIFELONG LEARNING, ACTIVE LIFESTYLES, AND VOLUNTEER ENGAGEMENT. THE OASIS SOUTHERN ILLINOIS RSVP PROGRAM WILL RECRUIT, TRAIN, AND PLACE 75 VOLUNTEERS WHO ARE 55 AND OLDER BY THE THIRD YEAR OF PROGRAM OPERATIONS. BUILDING ON ITS PROVEN MODEL AND EXPERTISE IN ENGAGING OLDER ADULT VOLUNTEERS, OASIS WILL ADDRESS THE PRIMARY FOCUS AREA OF EDUCATION TO IMPROVE EDUCATIONAL OUTCOMES FOR ECONOMICALLY DISADVANTAGED AND ACADEMICALLY AT-RISK CHILDREN. THERE IS CONSENSUS AMONG EDUCATION EXPERTS THAT IT IS CRITICALLY IMPORTANT FOR CHILDREN TO READ AT GRADE LEVEL BY THE END OF THIRD GRADE. RESEARCH HAS DEMONSTRATED THE CORRELATION BETWEEN A STUDENT'S READING ABILITY AT THIS POINT AND HIS OR HER SUBSEQUENT ACADEMIC SUCCESS. ILLINOISREPORTCARD.COM IN 2016-2017, THE STATE'S OFFICIAL SOURCE FOR INFORMATION ABOUT PUBLIC SCHOOLS IN ILLINOIS SHOWS 53.8 PERCENT AND 59.5 PERCENT OF THIRD GRADERS IN EAST ST. LOUIS AND AT LALUMIER ELEMENTARY IN CAHOKIA SCHOOL DISTRICTS RESPECTIVELY DO NOT DEMONSTRATE READINESS FOR THE FOURTH GRADE IN ENGLISH LANGUAGE ARTS; 83.3 PERCENT OF THIRD GRADERS AT LOVEJOY ELEMENTARY IN BROOKLYN SCHOOL DISTRICT DID NOT DEMONSTRATE READINESS TO ADVANCE IN ENGLISH LANGUAGE ARTS. TO MEET THIS NEED, OVER THE COURSE OF THREE YEARS, OASIS WILL RECRUIT, TRAIN, AND PLACE 75 UNDUPLICATED RSVP VOLUNTEERS WHO WILL SERVE DIRECTLY IN SCHOOLS (VOLUNTEER STATIONS) PROVIDING LITERACY TUTORING AND SUPPORT TO 255 STUDENTS IN THE PROPOSED SERVICE AREA. THESE VOLUNTEERS WILL PROVIDE MORE THAN 14,280 HOURS OF SERVICE. OF THE STUDENTS SERVED BY YEAR THREE, 90 PERCENT OF STUDENTS (230) WILL COMPLETE THE PROGRAM AND 65 PERCENT OF THOSE STUDENTS (150) WILL SHOW IMPROVED ACADEMIC PERFORMANCE IN LITERACY AS MEASURED BY PRE- AND POST-TESTS. THE OASIS SOUTHERN ILLINOIS RSVP PROGRAM WILL MEET THE CRITICAL COMMUNITY NEED OF IMPROVING STUDENTS' ACADEMIC PERFORMANCE IN LITERACY WHILE STRENGTHENING SCHOOL COMMUNITIES THROUGH THE PRESENCE OF CARING, WELL-TRAINED, OLDER ADULT VOLUNTEERS.

HOMELESS ASSISTANCE

HOMELESS ASSISTANCE

HOMELESS ASSISTANCE

HOMELESS ASSISTANCE

HOMELESS ASSISTANCE

BASIC CENTER PROGRAM FOR RUNAWAY AND HOMELESS YOUTH (BCP)

CONTINUUM OF CARE PROGRAM

AN ESTIMATED 75 RSVP VOLUNTEERS WILL SERVE AS TUTORS IN PUBLIC SCHOOLS IN FRANKLIN COUNTY INCLUDING NEW HAVEN SD, WASHINGTON SD, MERAMEC VALLEY R-3, SULLIVAN, ST. CLAIR R-8 AND UNION R-6 AND FRANKLIN COUNTY R-3 SCHOOL DISTRICTS. ALL 75 RSVP VOLUNTEERS WILL BE PLACED IN OUTCOME ASSIGNMENTS. BUILDING ON ITS PROVEN MODEL AND EXPERTISE IN ENGAGING OLDER ADULT VOLUNTEERS, OASIS WILL ADDRESS THE PRIMARY FOCUS AREA OF EDUCATION TO IMPROVE EDUCATIONAL OUTCOMES FOR ECONOMICALLY DISADVANTAGED AND ACADEMICALLY AT-RISK CHILDREN. TO MEET THIS NEED, OVER THE COURSE OF THREE YEARS, OASIS WILL RECRUIT, TRAIN, AND PLACE 75 UNDUPLICATED RSVP VOLUNTEERS WHO WILL SERVE DIRECTLY IN SCHOOLS (VOLUNTEER STATIONS) PROVIDING LITERACY TUTORING AND MENTORING SUPPORT TO 230 STUDENTS IN THE PROPOSED SERVICE AREA. THESE VOLUNTEERS WILL PROVIDE MORE THAN 6,640 HOURS OF SERVICE PER SCHOOL YEAR. OF THE STUDENTS SERVED BY YEAR THREE, 230 STUDENTS WILL COMPLETE THE PROGRAM AND 80 PERCENT OF THOSE STUDENTS (184) WILL SHOW IMPROVED ACADEMIC PERFORMANCE IN LITERACY AS MEASURED BY PRE- AND POST-READING TESTS. FRANKLIN COUNTY RSVP PROGRAM WILL MEET THE CRITICAL COMMUNITY NEED OF IMPROVING STUDENTS' ACADEMIC PERFORMANCE IN LITERACY WHILE STRENGTHENING SCHOOL COMMUNITIES THROUGH THE PRESENCE OF CARING, WELL-TRAINED, OLDER ADULT VOLUNTEERS. THE CNCS FEDERAL INVESTMENT OF $75,000 WILL BE SUPPLEMENTED BY $8,333 FROM FUNDING FROM CORPORATIONS AND FOUNDATIONS.

CONTINUUM OF CARE PROGRAM

CONTINUUM OF CARE PROGRAM

CONTINUUM OF CARE PROGRAM

FORMULA GRANTS TO LEAS

STREET OUTREACH

MULTIFAMILY HOUSING SERVICE COORDINATORS

FORMULA GRANTS TO LEAS

FORMULA GRANTS TO LEAS

FORMULA GRANTS TO LEAS

FORMULA GRANTS TO LEAS

BUDGET SHIFT: OAG OASES UNION OF VEGETABLE PRODUCERS

FORMULA GRANTS TO LEAS

PURPOSE: THE CONTINUUM OF CARE (COC) PROGRAM IS DESIGNED TO PROMOTE COMMUNITY-WIDE COMMITMENT TO THE GOAL OF ENDING HOMELESSNESS; PROVIDE FUNDING FOR EFFORTS BY NONPROFIT PROVIDERS, STATES, AND LOCAL GOVERNMENTS TO QUICKLY HOUSE HOMELESS INDIVIDUALS AND FAMILIES WHILE MINIMIZING THE TRAUMA AND DISLOCATION CAUSED TO HOMELESS INDIVIDUALS, FAMILIES, AND COMMUNITIES BY HOMELESSNESS; PROMOTE ACCESS TO AND EFFECTIVE UTILIZATION OF MAINSTREAM PROGRAMS BY HOMELESS INDIVIDUALS AND FAMILIES; AND OPTIMIZE SELF-SUFFICIENCY AMONG INDIVIDUALS AND FAMILIES EXPERIENCING HOMELESSNESS. THE COC PROGRAM INCLUDES GRANTS THAT ARE AVAILABLE TO SPECIFIC SUBPOPULATIONS OF PEOPLE EXPERIENCING HOMELESSNESS. THE GRANTS SPECIFICALLY SERVE YOUTH, DEFINED AS HOUSEHOLDS WHERE NO PERSON IS OVER THE AGE OF 24 UNDER THE YOUTH HOMELESS DEMONSTRATION PROGRAM (YHDP). THE GOAL OF THE YOUTH HOMELESSNESS DEMONSTRATION PROGRAM (YHDP) IS TO SUPPORT THE DEVELOPMENT AND IMPLEMENTATION OF A COORDINATED COMMUNITY APPROACH TO PREVENTING AND ENDING YOUTH HOMELESSNESS AND SHARING THAT EXPERIENCE WITH AND MOBILIZING COMMUNITIES AROUND THE COUNTRY TOWARD THE SAME END. THE NOTICE OF FUNDING OPPORTUNITY (NOFO) FOR NEW YHDP GRANTS IS FOUND AT HTTPS://WWW.HUD.GOV/PROGRAM_OFFICES/COMM_PLANNING/YHDP (CHOOSE THE MOST RECENT YHDP NOFO LISTED). THE NOFO FOR YHDP RENEWALS AND REPLACEMENTS IS FOUND AT HTTPS://WWW.HUD.GOV/PROGRAM_OFFICES/COMM_PLANNING/COC/COMPETITION (CHOOSE THE MOST RECENT COC/YHDP RENEWAL OR REPLACEMENT NOFO LISTED).; ACTIVITIES TO BE PERFORMED: THESE GRANTS MAY BE USED TO PAY FOR THE ELIGIBLE COSTS USED TO ESTABLISH AND OPERATE PROJECTS UNDER FIVE PROGRAM COMPONENTS: 1. PERMANENT HOUSING, WHICH INCLUDES PERMANENT SUPPORTIVE HOUSING FOR PERSONS WITH DISABILITIES, AND RAPID REHOUSING; 2. TRANSITIONAL HOUSING; 3. SUPPORTIVE SERVICES ONLY; 4. HOMELESS MANAGEMENT INFORMATION SYSTEMS (HMIS); AND 5. HOMELESSNESS PREVENTION (IN SOME CASES). ELIGIBLE COSTS WITHIN THESE PROJECTS INCLUDE: 1. LEASING OF A STRUCTURE OR STRUCTURES, OR PORTIONS THEREOF, TO PROVIDE HOUSING OR SUPPORTIVE SERVICES; 2. RENTAL ASSISTANCE, WHICH MAY BE SHORT-TERM, MEDIUM-TERM, OR LONG-TERM, AS WELL AS TENANT-BASED, PROJECT-BASED, OR SPONSOR-BASED, FOR TRANSITIONAL OR PERMANENT HOUSING; 3. SUPPORTIVE SERVICES TO ASSIST PROGRAM PARTICIPANTS OBTAIN AND MAINTAIN HOUSING; 4. OPERATING COSTS OF SUPPORTIVE HOUSING; 5. COSTS OF IMPLEMENTING AND OPERATING HMIS; 6. PROJECT ADMINISTRATIVE COSTS; 7. RELOCATION COSTS; AND 8. INDIRECT COSTS IN ACCORDANCE WITH 2 CFR PARTS 200, AS APPLICABLE. IN ADDITION TO USING GRANT FUNDS FOR THE ELIGIBLE COSTS DESCRIBED ABOVE, RECIPIENTS AND SUBRECIPIENTS IN CONTINUUMS OF CARE DESIGNATED AS HIGH PERFORMING COMMUNITIES MAY ALSO USE GRANT FUNDS TO PROVIDE HOUSING RELOCATION AND STABILIZATION SERVICES AND SHORT- AND/OR MEDIUM-TERM RENTAL ASSISTANCE TO YOUTH AT RISK OF HOMELESSNESS AS SET FORTH IN 24 CFR 576.103 AND 24 CFR 576.104, IF NECESSARY TO PREVENT YOUTH FROM BECOMING HOMELESS. NO ASSISTANCE PROVIDED UNDER PROGRAM (OR ANY STATE OR LOCAL GOVERNMENT FUNDS USED TO SUPPLEMENT THIS ASSISTANCE) MAY BE USED TO REPLACE STATE OR LOCAL FUNDS PREVIOUSLY USED, OR DESIGNATED FOR USE, TO ASSIST HOMELESS PERSONS OR PERSONS AT-RISK OF HOMELESSNESS.; EXPECTED OUTCOMES: DECREASE IN THE NUMBER OF YOUTH EXPERIENCING HOMELESSNESS, MORE SPECIFICALLY USING PERFORMANCE INDICATORS SUCH AS THE LENGTH OF TIME HOMELESS, RETURNS TO HOMELESSNESS OVER TIME, AND EXITS TO PERMANENT HOUSING. COC PERFORMANCE PROFILE REPORTS CAN BE FOUND AT: HTTPS://WWW.HUDEXCHANGE.INFO/PROGRAMS/COC/COC-PERFORMANCE-PROFILE-REPORTS/; INTENDED BENEFICIARIES: YOUTH DEFINED AS HOUSEHOLDS WHERE NO PERSON IS OVER THE AGE OF 24; SUBRECIPIENT ACTIVITIES: THE SUBRECIPIENT ACTIVITIES ARE UNKNOWN AT THE TIME OF AWARD

CONTINUUM OF CARE PROGRAM

THIS AWARD FUNDS THE APPROVED 2023-24 RSVP PROGRAM. YOUR 2023-24 STATUTORY MATCH IS 30% AND YOUR BUDGETARY MATCH IS 30.0%.

SBIR PHASE I: NANOCOMPOSITE MEMBRANES FOR SOLVENT-RESISTANT NANOFILTRATION AND REVERSE OSMOSIS

SBIR PHASE I: HIGH PERMEABILITY THIN-FILM NANOCOMPOSITE MEMBRANES FOR REVERSE OSMOSIS DESALINATION

CONTINUUM OF CARE PROGRAM

THIS AWARD FUNDS THE APPROVED 2022-23 RSVP PROGRAM. YOUR 2022-23 STATUTORY MATCH IS 30% AND YOUR BUDGETARY MATCH IS 30.0%.

CONTINUUM OF CARE PROGRAM

VALUE- ADDED AGRICULTURAL PRODUCT MARKET DEVELOPMENT GRANTS

NATURAL MIXTURES FROM EXPIRED HUMAN PLATELETS FOR PERIODONTAL TISSUE ENGINEERING

URBAN OASIS PROJECT WILL INCREASE LOCAL PRODUCE SALES AT NEW AND EXISTING FARMERS MARKETS IN SOUTH FLORIDA. THE PROJECT WILL FOCUS ON THE GENERATION OF PRINT AND DIGITAL MARKETING AND PROMOTION MATERIALS SUCH AS QUARTERLY PRINT CAMPAIGNS SOCIAL MEDIA ONLINE PROMOTION AND A WEEKLY ENEWSLETTER. THE PROJECT WILL BENEFIT CONSUMERS AND INCREASE SALES FOR AGRICULTURAL PRODUCERS.

REAP RENEWABLE ENERGY SYSTEM (RES) GRANT UNRESTRICTED AMOUNT

AN ESTIMATED 75 RSVP VOLUNTEERS WILL SERVE AS TUTORS IN PUBLIC SCHOOLS IN LINN COUNTY INCLUDING MARCELINE R-5, BUCKLIN R-2, MEADVILLE R-4, BROOKFIELD R-3 AND LINN COUNTY R-1 SCHOOL DISTRICTS. ALL 75 RSVP VOLUNTEERS WILL BE PLACED IN OUTCOME ASSIGNMENTS. BUILDING ON ITS PROVEN MODEL AND EXPERTISE IN ENGAGING OLDER ADULT VOLUNTEERS, OASIS WILL ADDRESS THE PRIMARY FOCUS AREA OF EDUCATION TO IMPROVE EDUCATIONAL OUTCOMES FOR ECONOMICALLY DISADVANTAGED AND ACADEMICALLY AT-RISK CHILDREN. TO MEET THIS NEED, OVER THE COURSE OF THREE YEARS, OASIS WILL RECRUIT, TRAIN, AND PLACE 75 UNDUPLICATED RSVP VOLUNTEERS WHO WILL SERVE DIRECTLY IN SCHOOLS (VOLUNTEER STATIONS) PROVIDING LITERACY TUTORING AND MENTORING SUPPORT TO 230 STUDENTS IN THE PROPOSED SERVICE AREA. THESE VOLUNTEERS WILL PROVIDE MORE THAN 6,640 HOURS OF SERVICE PER SCHOOL YEAR. OF THE STUDENTS SERVED BY YEAR THREE, 230 STUDENTS WILL COMPLETE THE PROGRAM AND 80 PERCENT OF THOSE STUDENTS (184) WILL SHOW IMPROVED ACADEMIC PERFORMANCE IN LITERACY AS MEASURED BY PRE- AND POST-READING TESTS. LINN COUNTY RSVP PROGRAM WILL MEET THE CRITICAL COMMUNITY NEED OF IMPROVING STUDENTS' ACADEMIC PERFORMANCE IN LITERACY WHILE STRENGTHENING SCHOOL COMMUNITIES THROUGH THE PRESENCE OF CARING, WELL-TRAINED, OLDER ADULT VOLUNTEERS. THE CNCS FEDERAL INVESTMENT OF $75,000 WILL BE SUPPLEMENTED BY $8,333 FROM MATCH FUNDING FROM THE NORMAN J. STUPP FOUNDATION, SAIGH FOUNDATION, DOLLAR GENERAL LITERACY FOUNDATION AND PARTNER REVENUE.

URBAN OASIS BUILDING NEW LOCAL FOOD MAR

AN ESTIMATED 75 RSVP VOLUNTEERS WILL SERVE. OF THIS NUMBER, 75 RSVP VOLUNTEERS WILL BE PLACED IN OUTCOME ASSIGNMENTS. THEIR ACTIVITY WILL BE TUTORING IN PUBLIC SCHOOLS IN JEFFERSON COUNTY. THE PRIMARY FOCUS AREA OF THIS PROJECT IS EDUCATION. AT THE END OF THE THREE-YEAR GRANT, 150 K-3 STUDENTS WILL HAVE IMPROVED ACADEMIC PERFORMANCE AS MEASURED BY READING ASSESSMENTS USED BY THE INDIVIDUAL SCHOOL DISTRICTS SUCH AS FOUNTAS AND PINNELL, GATES MCGINITIE, OR IREADY DIAGNOSTIC. THE CNCS FEDERAL INVESTMENT OF $74,617 WILL BE SUPPLEMENTED BY $8,351 FROM FUNDING FROM CORPORATIONS AND FOUNDATIONS. THE OASIS INSTITUTE (OASIS), A 501 (C) (3) ORGANIZATION, IS PROPOSING TO IMPLEMENT A SENIOR CORPS RETIRED AND SENIOR VOLUNTEER PROGRAM (RSVP) IN JEFFERSON COUNTY, MISSOURI (MO-29). THE MISSION OF OASIS IS TO PROMOTE HEALTHY AGING THROUGH LIFELONG LEARNING, ACTIVE LIFESTYLES, AND VOLUNTEER ENGAGEMENT. THE OASIS JEFFERSON COUNTY RSVP PROGRAM WILL RECRUIT, TRAIN, AND PLACE VOLUNTEERS WHO ARE 55 AND OLDER BY THE THIRD YEAR OF PROGRAM OPERATIONS. BUILDING ON ITS PROVEN MODEL AND EXPERTISE IN ENGAGING OLDER ADULT VOLUNTEERS, OASIS WILL ADDRESS THE PRIMARY FOCUS AREA OF EDUCATION TO IMPROVE EDUCATIONAL OUTCOMES FOR ECONOMICALLY DISADVANTAGED AND ACADEMICALLY AT-RISK CHILDREN. THERE IS CONSENSUS AMONG EDUCATION EXPERTS THAT IT IS CRITICALLY IMPORTANT FOR CHILDREN TO READ AT GRADE LEVEL BY THE END OF THIRD GRADE. RESEARCH HAS DEMONSTRATED THE CORRELATION BETWEEN A STUDENT'S READING ABILITY AT THIS POINT AND HIS OR HER SUBSEQUENT ACADEMIC SUCCESS. HOWEVER, NATIONALLY MILLIONS OF STUDENTS FAIL TO MEET THIS BENCHMARK EACH YEAR, AS DO THOUSANDS OF STUDENTS IN MISSOURI AND IN THE PROPOSED RSVP SERVICE AREAS. ON THE 2015 NATIONAL ASSESSMENT OF EDUCATIONAL PROGRESS (NAEP) READING EXAM, 63.7 PERCENT OF 4TH GRADERS IN MISSOURI WERE NOT READING AT THE "PROFICIENT" LEVEL. ON THE ENGLISH/LANGUAGE ARTS PORTION OF THE 2016 MISSOURI ASSESSMENT PROGRAM (MAP), 39.3 PERCENT OF ALL THIRD GRADERS IN THE STATE FELL BELOW THE PROFICIENT LEVEL. IN JEFFERSON COUNTY, 50.7 PERCENT OF THIRD GRADERS ARE NOT PROFICIENT IN READING. TO MEET THIS NEED, OVER THE COURSE OF THREE YEARS, OASIS WILL RECRUIT, TRAIN, AND PLACE 75 UNDUPLICATED RSVP VOLUNTEERS WHO WILL SERVE DIRECTLY IN 19 SCHOOLS (VOLUNTEER STATIONS) PROVIDING LITERACY TUTORING AND SUPPORT TO 255 STUDENTS THE PROPOSED SERVICE AREA. THESE VOLUNTEERS WILL PROVIDE MORE THAN 5,040 HOURS OF SERVICE. OF THE STUDENTS SERVED BY YEAR THREE, 90 PERCENT OF STUDENTS (230) WILL COMPLETE THE PROGRAM AND 65 PERCENT OF STUDENTS (150) WILL SHOW IMPROVED ACADEMIC PERFORMANCE IN LITERACY AS MEASURED BY PRE- AND POST-TESTS. THE OASIS JEFFERSON COUNTY RSVP PROGRAM WILL MEET THE CRITICAL COMMUNITY NEED OF IMPROVING STUDENTS' ACADEMIC PERFORMANCE IN LITERACY WHILE STRENGTHENING SCHOOL COMMUNITIES THROUGH THE PRESENCE OF CARING, WELL- TRAINED, OLDER ADULT VOLUNTEERS.

AMERICORPS NATIONAL

VALUE- ADDED AGRICULTURAL PRODUCT MARKET DEVELOPMENT GRANTS

BUILD SUSTAINABLE PARTNERSHIPS AMONG GOVERNMENT STAKEHOLDERS AND CIVIL SOCIETY ORGANIZATIONS TO WORK TOGETHER TO COMBAT HUMAN TRAFFICKING THROUGH AWARENESS RAISING CAMPAIGNS, TRAINING, AND MENTORSHIP

REAP RENEWABLE ENERGY SYSTEM (RES) GRANT UNRESTRICTED AMOUNT

CONTINUUM OF CARE PROGRAM

HOMELESS ASSISTANCE

THIS AWARD FUNDS THE APPROVED 2024?25 RSVP PROGRAM. YOUR 2024?25 STATUTORY MATCH IS 0% AND YOUR BUDGETARY MATCH IS 0%. THIS AWARD IS APPROVED TO ADD $2,500 IN ONE-TIME ADDITIONAL FUNDS FOR TRAVEL RELATED TO TRAINING IN FY 24.

PROMOTE ECONOMIC AND SOCIAL INDEPENDENCE IN YOUNG WOMEN THROUGH TRAINING IN COMMERCIALLY DEMANDED PROFESSIONS,ENTREPRENEURSHIP, CIVICS AND LEADERSHIP

THIS GRANT SUPPORTS THE COSTS INCURRED TO IMPLEMENT MEASURES TO RESPOND TO THE NOVEL CORONAVIRUS 2019 (COVID-19), WHICH MAY INCLUDE WORKPLACE SAFETY, MARKET PIVOTS, RETROFITTING FACILITIES, TRANSPORTATION, WORKER HOUSING, AND MEDICAL EXPENSES. IT PROVIDES NEEDED RELIEF TO THE FOOD PROCESSORS, DISTRIBUTORS, FARMERS MARKETS, AND PRODUCERS FOR THEIR COSTS INCURRED BETWEEN JANUARY 27, 2020, THE DATE UPON WHICH THE PUBLIC HEALTH EMERGENCY WAS DECLARED BY THE U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICE (HHS) UNDER SECTION 319 OF THE PUBLIC HEALTH SERVICE ACT, AND DECEMBER 31, 2021. BENEFICIARIES INCLUDE THE EMPLOYEES OF THE FOOD PROCESSORS, DISTRIBUTORS, FARMERS MARKETS, AND PRODUCERS.

SEC 9007 REAP-RENEW ENERGY SYSTEMS GRANTS, $20,000 OR LESS (MAN)

SEC 9007 REAP-RENEW ENERGY SYSTEMS GRANTS, $20,000 OR LESS (MAN)

TO SUPPORT THE CREATION AND INSTALLATION OF OUTDOOR PORTRAIT MURALS BASED ON THE IDENTITIES AND EXPERIENCES OF LOCAL YOUTH.

SEC. 9007 REAP-RENEW ENERGY SYS GRANTS (MAN)

SEC 9007 REAP-RENEW ENERGY SYSTEMS GRANTS, $20,000 OR LESS (MAN)

THIS GRANT SUPPORTS THE COSTS INCURRED TO IMPLEMENT MEASURES TO RESPOND TO THE NOVEL CORONAVIRUS 2019 (COVID-19), WHICH MAY INCLUDE WORKPLACE SAFETY, MARKET PIVOTS, RETROFITTING FACILITIES, TRANSPORTATION, WORKER HOUSING, AND MEDICAL EXPENSES. IT PROVIDES NEEDED RELIEF TO THE FOOD PROCESSORS, DISTRIBUTORS, FARMERS MARKETS, AND PRODUCERS FOR THEIR COSTS INCURRED BETWEEN JANUARY 27, 2020, THE DATE UPON WHICH THE PUBLIC HEALTH EMERGENCY WAS DECLARED BY THE U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICE (HHS) UNDER SECTION 319 OF THE PUBLIC HEALTH SERVICE ACT, AND DECEMBER 31, 2021. BENEFICIARIES INCLUDE THE EMPLOYEES OF THE FOOD PROCESSORS, DISTRIBUTORS, FARMERS MARKETS, AND PRODUCERS.

UNKNOWN TITLE

CONTINUUM OF CARE PROGRAM

SEC 9007 REAP-RENEW ENERGY EFFICIENCY IMPROVE GRANTS, $20,000 OR LESS (MAN)

OASIS YOUTH CONTINUUM OF SERVICES: BASIC CENTER

EXECUTIVE SUMMARY AN ESTIMATED 75 RSVP VOLUNTEERS WILL SERVE AS TUTORS IN PUBLIC SCHOOLS IN AUDRAIN COUNTY INCLUDING MEXICO, VAN-FAR R-1 AND COMMUNITY R-6 SCHOOL DISTRICTS. ALL 75 RSVP VOLUNTEERS WILL BE PLACED IN OUTCOME ASSIGNMENTS. BUILDING ON ITS PROVEN MODEL AND EXPERTISE IN ENGAGING OLDER ADULT VOLUNTEERS, OASIS WILL ADDRESS THE PRIMARY FOCUS AREA OF EDUCATION TO IMPROVE EDUCATIONAL OUTCOMES FOR ECONOMICALLY DISADVANTAGED AND ACADEMICALLY AT-RISK CHILDREN. TO MEET THIS NEED, OVER THE COURSE OF THREE YEARS, OASIS WILL RECRUIT, TRAIN, AND PLACE 75 UNDUPLICATED RSVP VOLUNTEERS WHO WILL SERVE DIRECTLY IN SCHOOLS (VOLUNTEER STATIONS) PROVIDING LITERACY TUTORING AND MENTORING SUPPORT TO 230 STUDENTS IN THE PROPOSED SERVICE AREA. THESE VOLUNTEERS WILL PROVIDE MORE THAN 6,640 HOURS OF SERVICE PER SCHOOL YEAR. OF THE STUDENTS SERVED BY YEAR THREE, 230 STUDENTS WILL COMPLETE THE PROGRAM AND 80 PERCENT OF THOSE STUDENTS (184) WILL SHOW IMPROVED ACADEMIC PERFORMANCE IN LITERACY AS MEASURED BY PRE-AND POST READING TESTS. AUDRAIN COUNTY RSVP PROGRAM WILL MEET THE CRITICAL COMMUNITY NEED OF IMPROVING STUDENTS' ACADEMIC PERFORMANCE IN LITERACY WHILE STRENGTHENING SCHOOL COMMUNITIES THROUGH THE PRESENCE OF CARING, WELL-TRAINED, OLDER ADULT VOLUNTEERS. THE CNCS FEDERAL INVESTMENT OF $75,000 WILL BE SUPPLEMENTED BY $8,333 FROM FUNDING FROM CORPORATIONS AND FOUNDATIONS.

REAP RENEWABLE ENERGY SYSTEM (RES) GRANT UNRESTRICTED AMOUNT