Coi Inc

STREAMBANK STABILIZATION FOR DSRS 47-01-24-5133-404 THRU 405, 25 SITES IN UNICOI COUNTY, TN.

A PORTABLE PET INSERT SYSTEM FOR SIMULTANEOUS TOF-PET AND MR BRAIN IMAGING - 1 PROJECT SUMMARY 2 3 NEUROLOGICAL AND MENTAL HEALTH DISORDERS COST THE UNITED STATES MORE THAN 800 BILLION EACH YEAR. ACQUIRING BOTH 4 PET AND MRI IMAGES IS CRITICAL IN CHARACTERIZING CONDITIONS SUCH AS BRAIN TUMORS, EPILEPSY, ALZHEIMER’S DISEASE, 5 AND DEPRESSION. TODAY, MOST PATIENTS MUST UNDERGO TWO SEPARATE STUDIES ON PET/CT AND MRI SYSTEMS TO 6 ACQUIRE PET AND MRI DATA, WHICH IS INCONVENIENT FOR BOTH THE PATIENT AND REFERRING PHYSICIAN AND LEADS TO 7 SOFTWARE-BASED IMAGE FUSION ERROR, EXTRA RADIATION EXPOSURE FROM THE CT SCAN, AND TYPICALLY WEEKS OF DELAY TO 8 ACQUIRE BOTH PIECES OF INFORMATION NECESSARY TO MAKE INFORMED DECISIONS ABOUT THE DISEASE TREATMENT. HYBRID 9 PET/MRI CAN ACQUIRE PET AND MRI STUDIES SIMULTANEOUSLY, AVOIDING THE STATED ISSUES WITH TWO SEPARATE STUDIES. 10 UNFORTUNATELY, THE ACCESS TO PET/MRI IS LIMITED BY THE HIGH COST OF THE COMMERCIAL PERMANENTLY-INTEGRATED 11 PET+MRI SYSTEMS, WHICH IS ABOUT $5M FOR PURCHASING THE SYSTEM PLUS A $1.5-2M ROOM RENOVATION COST. TODAY, 12 ONLY ABOUT 50 INTEGRATED PET/MRI SYSTEMS ARE INSTALLED IN THE US COMPARED TO 13,500 INSTALLED MRI SYSTEMS. 13 MOREOVER, CURRENT WHOLE-BODY PET/CT AND PET/MRI SYSTEMS ARE LIMITED IN SPATIAL RESOLUTION AND PHOTON 14 SENSITIVITY ACHIEVABLE FOR BRAIN IMAGING. TO ADDRESS THESE NEEDS, PETCOIL IS DEVELOPING A PORTABLE TOF-PET 15 SYSTEM THAT CAN BE INSERTED INTO (AND REMOVED FROM) ANY MRI SYSTEM TO LOWER THE COST TO ACHIEVE SIMULTANEOUS 16 PET/MR BRAIN IMAGING BY UP TO 10-FOLD COMPARED TO PROCURING A PERMANENTLY-INTEGRATED PET/MRI SYSTEM. IT CAN 17 BE USED WITH MULTIPLE MRI SYSTEMS FOR DIFFERENT APPLICATIONS (E.G., CLINICAL AND RESEARCH) OR EMPLOYED AS A 18 PORTABLE STAND-ALONE SYSTEM TO PROVIDE FLEXIBLE PET IMAGING CAPABILITY. MOREOVER, THE PET SYSTEM WILL ACHIEVE 19 OVER 3 TIMES HIGHER PHOTON SENSITIVITY AND OVER 4 TIMES FINER VOLUMETRIC SPATIAL RESOLUTION COMPARED TO STATE-OF- 20 THE-ART PET/MRI SYSTEMS. IN PHASE I, WE HAVE DEVELOPED A PARTIAL PET RING OF DETECTOR MODULES BASED ON A 21 SCALABLE DETECTOR MODULE DESIGN AND VERIFIED ITS PERFORMANCE AND MRI COMPATIBILITY. IN PHASE II, WE WILL CONTINUE 22 OUR COLLABORATION WITH DR. CRAIG LEVIN AT STANFORD UNIVERSITY TO DEVELOP THE FULL PET INSERT SYSTEM (AIM 1), VALIDATE 23 THE PERFORMANCE AND MRI COMPATIBILITY OF THE PET INSERT (AIM 2), AND CONDUCT FIRST-IN-HUMAN PILOT STUDIES TO 24 VALIDATE THE CLINICAL IMAGE QUALITY ACQUIRED WITH THE PET INSERT (AIM 3). THE OUTCOME OF PHASE II WILL BE THE FIRST 25 COMMERCIAL PROTOTYPE RADIOFREQUENCY (RF)-PENETRABLE TOF-PET INSERT FOR SIMULTANEOUS PET/MR AND VALIDATION 26 OF ITS IMAGE QUALITY IN CLINICAL PILOT STUDIES OF NEUROLOGICAL DISORDERS. THE DATA COLLECTED IN THE FIRST-IN-HUMAN STUDY 27 WILL FORM THE BASIS OF THE 510(K) SUBMISSION OF THE DEVICE. WE CONTEND THAT THE PROPOSED PET INSERT, WHICH ALLOWS 28 INSTITUTIONS WITH AT LEAST ONE MRI SYSTEM TO ACHIEVE PET/MRI WITH UP TO 10-FOLD LOWER COST AND SUPERIOR PET 29 IMAGE QUALITY COMPARED TO CURRENT PERMANENTLY-INTEGRATED PET/MR PRODUCTS OFFERED ON THE MARKET, WILL FACILITATE 30 DISSEMINATION OF AND ACCESS TO PET/MRI FOR STUDYING NEUROLOGICAL AND MENTAL HEALTH DISORDERS.

COMMERCIALIZATION READINESS FOR A PORTABLE PET INSERT SYSTEM FOR SIMULTANEOUS TOF-PET AND MR BRAIN IMAGING - PROJECT SUMMARY NEUROLOGICAL AND MENTAL HEALTH DISORDERS COST THE UNITED STATES MORE THAN $800 BILLION EACH YEAR. ALZHEIMER’S DISEASE (AD) ALONE COSTS THE U.S. AN ESTIMATED $345 BILLION IN 2023. THE RECENT APPROVAL OF ANTI-AMYLOID TREATMENTS FOR AD UNDERSCORES THE URGENCY FOR EARLY DIAGNOSIS. ACCURATE DIAGNOSIS OF VARIOUS NEUROLOGICAL AND MENTAL HEALTH DISORDERS, INCLUDING BRAIN TUMORS, EPILEPSY, ALZHEIMER’S DISEASE, AND DEPRESSION, OFTEN REQUIRES BOTH PET AND MRI SCANS, TYPICALLY INVOLVING SEPARATE PET/CT AND MRI PROCEDURES. THIS SEQUENTIAL APPROACH NOT ONLY CAUSES PATIENT INCONVENIENCE AND DELAYED DIAGNOSIS, BUT IT ALSO LEADS TO IMAGE FUSION ERROR AND ADDITIONAL RADIATION EXPOSURE FROM THE CT SCAN. HYBRID PET/MRI SYSTEMS, CAPABLE OF SIMULTANEOUS PET AND MRI SCANNING, PRESENT A SOLUTION TO THESE CHALLENGES. HOWEVER, THEIR ADOPTION IS HINDERED BY THE PROHIBITIVE COSTS OF CURRENT PERMANENTLY-INTEGRATED SYSTEMS, WHICH INCLUDES APPROXIMATELY $5 MILLION FOR PURCHASING THE SYSTEM, PLUS AN ADDITIONAL $1.5-2 MILLION FOR ROOM RENOVATIONS. IN THE U.S., ONLY ABOUT 60 INTEGRATED PET/MRI SYSTEMS ARE IN USE, COMPARED TO 13,500 MRI SYSTEMS. EXISTING WHOLE-BODY PET/CT AND PET/MRI SYSTEMS ARE ALSO LIMITED IN SPATIAL RESOLUTION AND PHOTON SENSITIVITY NEEDED FOR BRAIN IMAGING. PETCOIL IS ADDRESSING THESE CHALLENGES BY COMMERCIALIZING A PORTABLE, BRAIN-DEDICATED PET SYSTEM THAT CAN BE INSERTED INTO (AND REMOVED FROM) ANY MRI SYSTEM TO LOWER THE COST TO ACHIEVE SIMULTANEOUS PET/MRI BY 10-FOLD COMPARED TO CURRENT PERMANENTLY-INTEGRATED PET/MRI SYSTEM. THE PETCOIL INSERT SYSTEM ALSO ACHIEVES OVER 3 TIMES HIGHER PHOTON SENSITIVITY AND OVER 4 TIMES FINER VOLUMETRIC SPATIAL RESOLUTION OVER CURRENT PET/MRI SYSTEMS, ENHANCING LESION DETECTION AND QUANTIFICATION IN BRAINS. IN PHASE II, WE DEVELOPED A FUNCTIONAL PET INSERT PROTOTYPE. THE CURRENT CRP PROGRAM FOCUSES ON OPTIMIZING THE DESIGN FOR MASS PRODUCTION AND PREPARING FOR REGULATORY SUBMISSION, WITH THREE SPECIFIC AIMS: (1) COLLABORATE WITH A PRODUCT DEVELOPMENT FIRM TO FINALIZE THE INDUSTRIAL DESIGN AND MANUFACTURING PROCESS FOR THE PRODUCTION UNIT. (2) VERIFY AND VALIDATE THE SAFETY AND PERFORMANCE OF THE PRODUCTION UNIT FOR REGULATORY SUBMISSION IN COLLABORATION WITH STANFORD UNIVERSITY. (3) WORK WITH A SEASONED CONSULTANT TO DEVELOP A REGULATORY STRATEGY AND PREPARE FOR THE FDA SUBMISSION. THIS INCLUDES HOLDING PRE- SUBMISSION MEETINGS WITH THE FDA, COMPILING THE REQUIRED MATERIALS, AND SUBMITTING THE REGULATORY APPLICATION. THIS CRP PROGRAM WILL CULMINATE IN A PRODUCTION-READY BRAIN PET INSERT, SET FOR MANUFACTURING AND REGULATORY SUBMISSION, POISED TO ENABLE WIDESPREAD DISSEMINATION OF PET/MRI TECHNOLOGY FOR CHARACTERIZING NEUROLOGICAL AND MENTAL HEALTH DISORDERS.

SAC-COVID: AN FDA-APPROVED PHASE III CLINICAL TRIAL EVALUATING THE SAFETY AND THERAPEUTIC EFFICACY OF CD24FC IN SEVERE COVID-19 PATIENTS

CD24 AS THERAPEUTIC TARGET FOR MULTIPLE SCLEROSIS-PHASE II COMPETING RENEWAL

TAS::89 0227::TAS RECOVERY; NEW PHASE I SBIR: RECOVERY ACT; TITLE: RECOVERY ACT - MULTI-PROTOCOL ENERGY MANAGEMENT GATEWAY FOR HOME-AREA NETWORKS; PI

A PHASE IIA TRIAL FOR THE SAFETY AND TOLERABILITY OF CD24FC IN PROPHYLAXIS OF GRAFT VS HOST DISEASE.

FAMILY TREATMENT COURT - 24JO

HIDALGO COUNTY IRRIGATION DISTRICT (HCID) LOCATED IN THE CITY OF MISSION, HIDALGO COUNTY, TEXAS WILL CONSTRUCT A NEW PUMP STATION TO INCREASE RELIABILITY AND FLEXIBILITY TO DIVERT WATER FROM THE RIO GRANDE RIVER DURING PERIODS OF DROUGHT. HCIDS CURRENT RIVER LIFT STATION SUFFERS OPERATIONAL LIMITATIONS DUE TO PERSISTENT LOW WATER LEVELS. SOUTH TEXAS RIO GRANDE IS EXPERIENCING THE WORST DROUGHT CONDITIONS IN 25 YEARS, AND THE LOW RIVER LEVELS ARE EXACERBATED BY THE CURRENT DROUGHT. HCID PROVIDES WATER TO AGRICULTURAL PRODUCERS, AQUA SPECIAL UTILITY DISTRICT FOR MUNICIPAL POTABLE WATER NEEDS, MOORE AIRFIELD FEDERAL RESEARCH FACILITY, AND FRONTERA GENERATION FOR POWER. THIS PROJECT IS SUPPORTED BY THE REGION M WATER PLANNING GROUPS 2021 WATER PLAN THAT FOCUSES ON WATER MANAGEMENT STRATEGIES AND DROUGHT PLANNING.

MULTISCALE BIOINSPIRED ENHANCEMENT OF NATURAL-FIBER COMPOSITES FOR GREEN VEHICLES

24TH CIRCUIT FAMILY AND ADULT TREATMENT COURT EXPANSION - THE 24TH JUDICIAL CIRCUIT ADULT AND FAMILY TREATMENT COURT ARE COLLABORATING FOR APPLICATION OF A SAMHSA GRANT TO EXPAND SUBSTANCE USE DISORDER TREATMENT CAPACITY IN ADULT AND FAMILY TREATMENT COURTS. WHILE THE ADULT TREATMENT COURT HAS BEEN OPERATIONAL SINCE 2007, IT HAS ONLY BEEN SUSTAINED USING A MODEST STATE BUDGET AND NO FEDERAL GRANTS HAVE BEEN APPLIED FOR. THE FAMILY TREATMENT COURT IS NOW IN THE FIFTH BUDGET YEAR OF A SIMILAR SAMHSA GRANT WHICH WAS RECEIVED IN 2019 FOR PROGRAM DEVELOPMENT AND WILL RELY ON GRANT FUNDING TO CONTINUE PROVIDING SUPPORTED ACCESS TO PREVENTION, HARM REDUCTION, TREATMENT AND RECOVERY SUPPORT SERVICES. OVERALL GOAL OF THE PROJECT IS TO ENSURE MORE INDIVIDUALS INVOLVED IN THE LEGAL SYSTEM HAVE ACCESS TO CO-OCCURRING SUBSTANCE USE DISORDER TREATMENT. MISSOURI'S DEPARTMENT OF MENTAL HEALTH MAINTAINS INDIVIDUAL COUNTY PROFILES IN REGARD TO SUBSTANCE USE AND MENTAL HEALTH IN THE COMMUNITY. THE 24TH CIRCUIT SERVES ST FRANCOIS, STE GENEVIEVE, MADISON, AND WASHINGTON COUNTY MISSOURI. COLLECTIVE STATISTICS OF THOSE FOUR COUNTIES INDICATE THERE WERE 772 DRUG CONVICTIONS AND OUT-OF-HOME PLACEMENTS RELATED TO SUBSTANCES USE IN 2023. IT WAS ALSO REPORTED ALL FOUR COUNTIES COMBINED SAW ONLY 105 TREATMENT COURT PARTICIPANTS IN THAT SAME YEAR; MEANING ONLY 13.6% OF THOSE INDIVIDUALS ENTERED INTO A PROGRAM THAT COULD PROVIDE STRUCTURED SUPPORT TO HELP MEET THEIR NEEDS. THE ADULT TREATMENT COURT CURRENTLY SERVES 27 PARTICIPANTS, DOWN FROM 36 WITHIN THE LAST BUDGET YEAR DUE TO 9 SUCCESSFUL PROGRAM COMPLETIONS, WHILE FAMILY TREATMENT COURT CURRENTLY SERVES 11 PARTICIPANTS, DOWN FROM 29 WITHIN THE LAST BUDGET YEAR DUE TO 8 SUCCESSFUL PROGRAM COMPLETIONS. THE PROJECT STRIVES TO BE ABLE TO SERVE A MINIMUM NUMBER OF 40 INDIVIDUALS PER YEAR, TOTALING AT LEAST 200 BY PROJECT END WITH THE HOPES OF REUNIFYING PARENTS AND CHILDREN INTO SAFE AND SOBER HOMES AND REDUCING RECIDIVISM OF CRIMINAL OFFENSES RELATED TO SUBSTANCE USE OR UNTREATED MENTAL HEALTH. A MEASURABLE OBJECTIVE TO MEET THE GOALS OF INCREASING PARTICIPATION IS FOR KEY PROJECT STAFF TO BECOME MORE INVOLVED IN COMMUNITY COLLABORATION TO ENSURE A LARGER PERCENTAGE OF THESE CASES ARE BEING REFERRED FOR PROGRAMMING. IF WE CAN EDUCATE REFERRAL SOURCES ABOUT THE BENEFITS OF THE PROGRAM AND STREAMLINE THE REFERRAL PROCESS, WE HAVE THE POTENTIAL TO REDUCE THE AMOUNT OF TIME IT TAKES FROM POINT OF INCIDENT TO START OF SUBSTANCE USE AND CO-OCCURRING DISORDER TREATMENT.

CD24 TARGETING FOR MULTIPLE SCLEROSIS: A FIRST-IN-HUMAN PHASE I STUDY

A PORTABLE PET INSERT SYSTEM FOR SIMULTANEOUS TOF-PET AND MR BRAIN IMAGING

PHASE IIB TRIAL OF CD24FC FOR GVHD PROPHYLAXIS, IND 127,363 (01/29/2016)

ASSISTED HOUSING STABILITY AND ENERGY AND GREEN RETROFIT INVESTMENTS PROGRAM (RECOVERY ACT FUNDED)

OTHER-TECH

COMMUNITY INFRASTRUCTURE

TITLE: WORKING TOGETHER TO REDUCE YOUTH SUBSTANCE ABUSE IN UNICOI COUNTY. THE COMMUNITY INITIATIVE WILL REDUCE SUBSTANCE ABUSE AMONG YOUTH AGES 12-17 AND EDUCATE ADULTS ON THE DANGERS OF YOUTH USE.

STREAMBANK STABILIZATION FOR DSR 5110-401 AT MCINTURFF SPRINS ROAD IN UNICOI COUNTY, TN. EZFG ID 6000014323

ARTS-CULTURE-TOURISM

ASSISTANCE TO FIREFIGHTERS GRANTS

REAL-TIME MOTION CORRECTION METHOD FOR A PORTABLE, HIGH-RESOLUTION TOF PET SCANNER FOR IMAGING THE BRAIN, HEAD, AND NECK - HEAD AND NECK CANCER (HNC), INCLUDING CANCERS OF THE ORAL CAVITY AND OROPHARYNX, IS THE SIXTH MOST COMMON CANCER AND THE NINTH LEADING CAUSE OF CANCER-RELATED DEATHS GLOBALLY. DESPITE ADVANCES IN PET IMAGING, A CRITICAL TOOL IN STAGING AND TREATMENT PLANNING, THE DETECTION OF CERVICAL LYMPH NODE METASTASES REMAINS CHALLENGING DUE TO THE LIMITED RESOLUTION OF CONVENTIONAL WHOLE-BODY PET SCANNERS. THIS LIMITATION RESULTS IN HIGH FALSE-NEGATIVE RATES, PARTICULARLY FOR SMALL (<7 MM) METASTASES IN CLINICALLY NODE-NEGATIVE PATIENTS. DUE TO THE HIGH PREVALENCE (20-30%) OF OCCULT LYMPH NODE METASTASES, MANY HNC PATIENTS UNDERGO ELECTIVE NECK DISSECTIONS TO REMOVE POTENTIALLY AFFECTED NODES, DESPITE THE ASSOCIATED RISKS AND MORBIDITY. ADDRESSING THIS UNMET NEED, THE HEAD PETCOIL IS A PORTABLE, HIGH-RESOLUTION, TIME-OF-FLIGHT (TOF) PET SYSTEM DESIGNED FOR BRAIN, HEAD, AND NECK IMAGING. COMPARED TO CONVENTIONAL PET SYSTEMS, THE HEAD PETCOIL OFFERS NEARLY SIX TIMES FINER SPATIAL RESOLUTION AND THREE TIMES HIGHER PHOTON SENSITIVITY, IMPROVING THE DETECTION OF TUMORS AND SMALL LYMPH NODE METASTASIS. TO REALIZE THIS IMPROVED RESOLUTION IN PATIENT STUDIES, IT IS CRITICAL TO CORRECT FOR IMAGE BLURRING DUE TO HEAD MOTION, WHICH CAN CAUSE DISPLACEMENTS THAT RANGE FROM 2 TO 5 MM. THIS PHASE I PROJECT AIMS TO DEVELOP AND VALIDATE REAL-TIME MOTION CORRECTION SOFTWARE FOR THE HEAD PETCOIL. AIM 1 IS TO DEVELOP ULTRA-FAST DATA PROCESSING AND IMAGE RECONSTRUCTION SOFTWARE CAPABLE OF GENERATING SHORT TIMEFRAME (1-5 SECONDS) PET IMAGES IN REAL TIME DURING DATA ACQUISITION. AIM 2 IS TO CREATE REAL-TIME MOTION ESTIMATION AND CORRECTION SOFTWARE TO CALCULATE MOTION FROM SHORT TIMEFRAME IMAGES AND PRODUCE MOTION-CORRECTED IMAGES WITHIN 5 MINUTES AFTER SCAN COMPLETION. AIM 3 WILL VERIFY THE ACCURACY OF THE MOTION CORRECTION METHOD USING PHANTOMS WITH SIMULATED HEAD MOTION. THE GOAL IS TO ENSURE MOTION-CORRECTED IMAGES MEET PERFORMANCE METRICS (E.G., SPATIAL RESOLUTION, CONTRAST-TO-NOISE RATIO) COMPARABLE TO STATIC IMAGES. BY THE END OF PHASE I, A ROBUST SOFTWARE PACKAGE CAPABLE OF GENERATING MOTION-CORRECTED IMAGES FOR THE PORTABLE, HIGH-RESOLUTION TOF PET SYSTEM WITHIN 5 MINUTES POST- SCAN WILL BE DELIVERED. PHASE II WILL REFINE THE REAL-TIME MOTION CORRECTION SOFTWARE IN IMAGING HNC PATIENTS AND COMPARE THE DIAGNOSTIC ACCURACY OF THE HEAD PETCOIL TO COMMERCIAL WHOLE-BODY PET SYSTEMS. THE HEAD PETCOIL HAS THE POTENTIAL TO TRANSFORM HNC IMAGING BY IMPROVING EARLY-STAGE DISEASE DETECTION, ENHANCING TREATMENT PLANNING, AND EXPANDING ACCESS TO ADVANCED TOF PET IMAGING.

TRANSFORMING PROSTATE CANCER DIAGNOSIS: FEASIBILITY TESTING OF A NOVEL SYSTEM FOR INTEGRATED ENDORECTAL MRI AND IN-BORE BIOPSY - PROJECT ABSTRACT THE DEVELOPMENT OF THE NOVEL OMNECOIL SYSTEM ALIGNS WITH THE NCI’S MISSION TO HELP PEOPLE LIVE LONGER, HEALTHIER LIVES BY PROVIDING A FASTER, MORE EFFICIENT, AND MORE ACCURATE DIAGNOSTIC TEST FOR THE ESTIMATED 1.4 MILLION MEN WHO DEVELOP PROSTATE CANCER EACH YEAR. THE OMNECOIL SYSTEM CONSISTS OF A DISPOSABLE 20 CM LONG ENDORECTAL COIL AND MULTICHANNEL NEEDLE GUIDE WITH A REUSABLE CLAMP STAND, EMBEDDED ELECTRONICS, AND BASEPLATE. THIS DYNAMIC, INNOVATIVE SYSTEM CAN WORK WITH ANY STANDARD MRI SCANNER, AND CAN BE USED BY RADIOLOGISTS OR UROLOGISTS TO PERFORM ENDORECTAL MRI AND IN-BORE MRI TARGETED BIOPSY OF THE PROSTATE AS A SINGLE PROCEDURE. THE GOAL OF THIS STTR PROJECT IS TO TAKE THE SYSTEM FROM THE CURRENT TESTED LABORATORY PROTOTYPE THROUGH A FEASIBILITY STUDY. THE HYPOTHESIS THAT OMNECOIL WILL ALLOW ENDORECTAL MRI AND IN-BORE MRI TARGETED BIOPSY OF THE PROSTATE IN ONE PROCEDURE, WITH COMPARABLE PERFORMANCE TO SINGLE CHANNEL IN-BORE MRI-TARGETED BIOPSY WILL BE TESTED VIA THE FOLLOWING AIMS: 1) CONFIRM THAT THE OMNECOIL SYSTEM ALLOWS FOR ENDORECTAL IMAGING AND IN-BORE TARGETED BIOPSY; AND 2) INVESTIGATE THE CANCER DETECTION RATE FOR THE OMNECOIL SYSTEM. THE INVESTIGATORS WILL RECRUIT 30 MEN WITH A SUSPICIOUS TARGET ON MRI (PI-RADS SCORE OF 4 OR 5) BUT NO SIGNIFICANT CANCER (PRIOR TRUS BIOPSY NEGATIVE OR GLEASON SCORE 6 CANCER ONLY) TO UNDERGO ENDORECTAL MRI WITH MRI- GUIDED BIOPSY USING THE OMNECOIL SYSTEM IN AN IRB AND IDE APPROVED STUDY AT OUR PARTNER RESEARCH INSTITUTION, OREGON HEALTH AND SCIENCE UNIVERSITY (OHSU). SUCCESS WILL BE DEFINED AS THE ACQUISITION OF DIAGNOSTIC TISSUE SAMPLES, AS DETERMINED BY PATHOLOGICAL REVIEW ESTABLISHING IF THE SAMPLES ARE ADEQUATE OR INADEQUATE FOR DIAGNOSIS. FOR CANCER DETECTION, INVESTIGATORS WILL MEASURE THE PERCENTAGE OF CANCER CONTAINING BIOPSIES OF SUSPICIOUS TARGETS. RESULTS ARE ANTICIPATED TO SHOW THE OMNECOIL SYSTEM ALLOWS FOR COMBINED IMAGING AND BIOPSY OF SUSPECTED CANCER SITES IN THE PROSTATE WITH COMPARABLE PERFORMANCE TO SINGLE-CHANNEL IN-BORE BIOPSY, THE BEST CURRENTLY AVAILABLE APPROACH. THESE RESULTS WOULD PROVIDE SUFFICIENT EVIDENCE OF CLINICAL FEASIBILITY TO JUSTIFY CONTINUED PRODUCT DEVELOPMENT AS WELL AS A PHASE II SINGLE-ARM MULTICENTER PIVOTAL TRIAL OF 150 SUBJECTS TO DEMONSTRATE CLINICAL EFFECTIVENESS. THE COMMERCIAL OPPORTUNITY IS PROMISING WITH A SUBMARKET OF 12,500 REPEAT BIOPSY PROCEDURES PER YEAR. AT A PRICE OF $1000 PER DISPOSABLE UNIT, THIS YIELDS A SERVICEABLE OBTAINABLE MARKET IN THE U.S. OF $12.5M AND AN ANNUAL GLOBAL MARKET AS $4B. INITIAL CUSTOMERS FOR THE OMNECOIL SYSTEM WILL BE RADIOLOGISTS AT U.S. ACADEMIC CENTERS, WORKING COLLABORATIVELY WITH THEIR INSTITUTIONAL UROLOGY COLLEAGUES.

CINDI STUDY: A PHASE II CLINICAL TRIAL TO COMBINE CD24FC WITH IPILIMUMAB AND NIVOLUMAB TO DECREASE IMMUNE RELATED ADVERSE EVENTS (IRAE)

TARGETING ENDOGENOUS SIALIDASES FOR TREATMENT OF ENDOTOXIC SHOCK

KITCHEN INCUBATOR

PURPOSE: THE VOLUNTEER INCOME TAX ASSISTANCE (VITA) GRANT WAS ESTABLISHED AS A MATCHING GRANT PROGRAM TO PROVIDE FUNDING FOR ORGANIZATIONS WHO SUPPORT COMMUNITY VOLUNTEER INCOME TAX ASSISTANCE. ACTIVITIES TO BE PERFORMED: THE VITA GRANT PROGRAM PROVIDES FINANCIAL SUPPORT TO ORGANIZATIONS WHO 1) EXTEND SERVICES TO UNDERSERVED POPULATIONS IN HARDEST TO REACH AREAS BOTH URBAN AND NON-URBAN; 2) INCREASE THE CAPACITY TO FILE RETURNS ELECTRONICALLY; 3) HEIGHTEN QUALITY CONTROL; 4) ENHANCE TRAINING OF VOLUNTEERS; AND 5) SIGNIFICANTLY IMPROVE THE ACCURACY RATE OF RETURNS PREPARED AT VITA SITES. END GOAL/EXPECTED OUTCOMES: VITA GRANT RECIPIENTS ARE EXPECTED TO 1) FOLLOW EXISTING GUIDANCE GOVERNING VITA SITE OPERATIONS; 2) ENSURE AT LEAST 90% OF RETURNS PREPARED ARE FOR INDIVIDUALS WHOSE INCOME IS EQUAL TO OR LESS THAN THE MAXIMUM EARNED INCOME TAX CREDIT (EITC) THRESHOLDS; 2) FILE ALL ELIGIBLE RETURNS ELECTRONICALLY; 3) ACHIEVE 100% OF THEIR RETURN PRODUCTION GOALS; 4) BECOME MORE EFFICIENT WITH GRANT FUNDS; AND 5) SHOW INCREMENTAL INCREASES IN RETURN PREPARATION EACH YEAR. INTENDED BENEFICIARIES: TAXPAYERS WHO ARE LOW TO MODERATE INCOME INDIVIDUALS, PERSONS WITH DISABILITIES, THOSE FOR WHOM ENGLISH IS A SECOND LANGUAGE, NATIVE AMERICANS, INDIVIDUALS LIVING IN RURAL AREAS, MEMBERS OF THE ARMED FORCES AND THEIR FAMILIES, AND THE ELDERLY. SUBRECIPIENT ACTIVITIES: SUBRECIPIENTS MAY BE UTILIZED BY GRANT RECIPIENTS TO HELP DELIVER KEY ELEMENTS OF THE PROGRAM AND MUST ADHERE TO GRANT PROGRAM GUIDELINES. BROADBAND: SPECIFIC ACTIVITIES RELATING TO BROADBAND USAGE ARE NOT KNOWN AT THE TIME OF AWARD.

PURPOSE: THE VOLUNTEER INCOME TAX ASSISTANCE (VITA) GRANT WAS ESTABLISHED AS A MATCHING GRANT PROGRAM TO PROVIDE FUNDING FOR ORGANIZATIONS WHO SUPPORT COMMUNITY VOLUNTEER INCOME TAX ASSISTANCE. ACTIVITIES TO BE PERFORMED: THE VITA GRANT PROGRAM PROVIDES FINANCIAL SUPPORT TO ORGANIZATIONS WHO 1) EXTEND SERVICES TO UNDERSERVED POPULATIONS IN HARDEST TO REACH AREAS BOTH URBAN AND NON-URBAN; 2) INCREASE THE CAPACITY TO FILE RETURNS ELECTRONICALLY; 3) HEIGHTEN QUALITY CONTROL; 4) ENHANCE TRAINING OF VOLUNTEERS; AND 5) SIGNIFICANTLY IMPROVE THE ACCURACY RATE OF RETURNS PREPARED AT VITA SITES. END GOAL/EXPECTED OUTCOMES: VITA GRANT RECIPIENTS ARE EXPECTED TO 1) FOLLOW EXISTING GUIDANCE GOVERNING VITA SITE OPERATIONS; 2) ENSURE AT LEAST 90% OF RETURNS PREPARED ARE FOR INDIVIDUALS WHOSE INCOME IS EQUAL TO OR LESS THAN THE MAXIMUM EARNED INCOME TAX CREDIT (EITC) THRESHOLDS; 2) FILE ALL ELIGIBLE RETURNS ELECTRONICALLY; 3) ACHIEVE 100% OF THEIR RETURN PRODUCTION GOALS; 4) BECOME MORE EFFICIENT WITH GRANT FUNDS; AND 5) SHOW INCREMENTAL INCREASES IN RETURN PREPARATION EACH YEAR. INTENDED BENEFICIARIES: TAXPAYERS WHO ARE LOW TO MODERATE INCOME INDIVIDUALS, PERSONS WITH DISABILITIES, THOSE FOR WHOM ENGLISH IS A SECOND LANGUAGE, NATIVE AMERICANS, INDIVIDUALS LIVING IN RURAL AREAS, MEMBERS OF THE ARMED FORCES AND THEIR FAMILIES, AND THE ELDERLY. SUBRECIPIENT ACTIVITIES: SUBRECIPIENTS MAY BE UTILIZED BY GRANT RECIPIENTS TO HELP DELIVER KEY ELEMENTS OF THE PROGRAM AND MUST ADHERE TO GRANT PROGRAM GUIDELINES. BROADBAND: SPECIFIC ACTIVITIES RELATING TO BROADBAND USAGE ARE NOT KNOWN AT THE TIME OF AWARD.

PURPOSE: THE VOLUNTEER INCOME TAX ASSISTANCE (VITA) GRANT WAS ESTABLISHED AS A MATCHING GRANT PROGRAM TO PROVIDE FUNDING FOR ORGANIZATIONS WHO SUPPORT COMMUNITY VOLUNTEER INCOME TAX ASSISTANCE. ACTIVITIES TO BE PERFORMED: THE VITA GRANT PROGRAM PROVIDES FINANCIAL SUPPORT TO ORGANIZATIONS WHO 1) EXTEND SERVICES TO UNDERSERVED POPULATIONS IN HARDEST TO REACH AREAS BOTH URBAN AND NON-URBAN; 2) INCREASE THE CAPACITY TO FILE RETURNS ELECTRONICALLY; 3) HEIGHTEN QUALITY CONTROL; 4) ENHANCE TRAINING OF VOLUNTEERS; AND 5) SIGNIFICANTLY IMPROVE THE ACCURACY RATE OF RETURNS PREPARED AT VITA SITES. END GOAL/EXPECTED OUTCOMES: VITA GRANT RECIPIENTS ARE EXPECTED TO 1) FOLLOW EXISTING GUIDANCE GOVERNING VITA SITE OPERATIONS; 2) ENSURE AT LEAST 90% OF RETURNS PREPARED ARE FOR INDIVIDUALS WHOSE INCOME IS EQUAL TO OR LESS THAN THE MAXIMUM EARNED INCOME TAX CREDIT (EITC) THRESHOLDS; 2) FILE ALL ELIGIBLE RETURNS ELECTRONICALLY; 3) ACHIEVE 100% OF THEIR RETURN PRODUCTION GOALS; 4) BECOME MORE EFFICIENT WITH GRANT FUNDS; AND 5) SHOW INCREMENTAL INCREASES IN RETURN PREPARATION EACH YEAR. INTENDED BENEFICIARIES: TAXPAYERS WHO ARE LOW TO MODERATE INCOME INDIVIDUALS, PERSONS WITH DISABILITIES, THOSE FOR WHOM ENGLISH IS A SECOND LANGUAGE, NATIVE AMERICANS, INDIVIDUALS LIVING IN RURAL AREAS, MEMBERS OF THE ARMED FORCES AND THEIR FAMILIES, AND THE ELDERLY. SUBRECIPIENT ACTIVITIES: SUBRECIPIENTS MAY BE UTILIZED BY GRANT RECIPIENTS TO HELP DELIVER KEY ELEMENTS OF THE PROGRAM AND MUST ADHERE TO GRANT PROGRAM GUIDELINES. BROADBAND: SPECIFIC ACTIVITIES RELATING TO BROADBAND USAGE ARE NOT KNOWN AT THE TIME OF AWARD.

THE LEVEL II GRANT WILL ALLOW PACOIMA BEAUTIFUL PARTNERS TO TAKE ACTION TO REDUCE RISK FROM TWO OF THE IDENTIFIED COMMUNITY PRIORITIES: AUTOMOTIVE S

DISTANCE LEARNING GRANT

EVALUATION OF THERAPEUTIC EFFICACY AND SAFETY OF NOVEL SMALL RNA TARGET DELIVERY PLATFORM IN VIVO.

SBIR PHASE I: PROSTATE CANCER DIAGNOSIS WITH AN INTEGRATED ENDORECTAL MRI AND TARGETED TRANSRECTAL BIOPSY

ST. FRANCOIS COUNTY, MISSOURI DRUG-FREE COMMUNITIES SUPPORT YOUTH SUBSTANCE USE PREVENTION PROJECT - ST. FRANCOIS COUNTY COMMUNITY PARTNERSHIP IN SOUTHEAST MISSOURI WILL UTILIZE THE STRATEGIC PREVENTION FRAMEWORK TO PLAN AND IMPLEMENT PROGRAMS TO PREVENT AND REDUCE YOUTH USE OF ALCOHOL AND TOBACCO. THE COALITION WILL MEET MONTHLY TO ACHIEVE ITS GOALS OF INCREASING COMMUNITY COLLABORATION AND REDUCING YOUTH SUBSTANCE USE. OBJECTIVES FOR THIS PROJECT ARE:  STRENGTHEN THE CAPACITY OF THE COALITION BY INCREASING MEMBERSHIP  DEVELOP FOUR ACTION COMMITTEES WITHIN THE COALITION TO ACHIEVE CERTAIN TASKS AND MILESTONES RELATED TO REDUCING YOUTH SUBSTANCE USE  INCREASE YOUTH PARTICIPATION IN THE COALITION  DEVELOP A YOUTH COALITION  INCREASE THE CAPACITY OF THE COALITION AND THE YOUTH COALITION BY DELIVERING TRAINING OPPORTUNITIES TO MEMBERS  IMPLEMENT THE EVIDENCE-BASED PROGRAM TOO GOOD FOR DRUGS IN LOCAL SCHOOLS  INCREASE YOUTH PERCEPTION OF RISK ASSOCIATED WITH ALCOHOL AND TOBACCO USE  IMPLEMENT THE PREVENTION PLUS WELLNESS PROGRAM IN LOCAL SCHOOLS  CONDUCT A RESPONSIBLE VENDOR CAMPAIGN  INCREASE PARENTAL PERCEPTION OF RISK ASSOCIATED WITH YOUTH VAPING THROUGH IMPLEMENTATION OF THE CATCH MY BREATH CAMPAIGN PROGRESS TOWARD GOALS AND OBJECTIVES WILL BE MEASURED BI-ANNUALLY THROUGH THE MISSOURI STUDENT SURVEY. CORE MEASURES THAT WILL BE COLLECTED ARE 1) PAST 30-DAY USE OF ALCOHOL, TOBACCO, MARIJUANA, AND PRESCRIPTION DRUGS; 2) PERCEPTION OF RISK AMONG YOUTH RESPONDENTS; 3) PERCEPTION OF PARENTAL DISAPPROVAL AMONG YOUTH RESPONDENTS; AND 4) PERCEPTION OF PEER DISAPPROVAL AMONG YOUTH RESPONDENTS. IN ADDITION TO THE MISSOURI STUDENT SURVEY, THE COALITION WILL COLLECT DATA THROUGHOUT THE YEAR DURING EVIDENCE-BASED EDUCATION SESSIONS. THE COALITION WILL REPORT ITS PROGRESS TO THE CENTERS FOR DISEASE CONTROL EACH YEAR BY COMPLETING PROGRESS REPORTS AND OTHER REPORTS LOCATED ON THE OFFICE OF NATIONAL DRUG CONTROL POLICY WEBSITE.

STAFFING FOR ADEQUATE FIRE AND EMERGENCY RESPONSE (SAFER)

ASSISTANCE TO FIREFIGHTERS GRANT

STTR PHASE I: FUNGAL EXPRESSION OF ANTIMICROBIAL PEPTIDES FOR ADDITION TO ANIMAL FEED

SBIR PHASE I: COMBINED ENDORECTAL PROSTATIC MAGNETIC RESONANCE IMAGING AND BIOPSY DEVICE TO ENABLE SINGLE COMBINED PROCEDURES

IMPACT AID PROGRAM TITLE VIII SECTION 8002

SBIR PHASE I: EXPERCOIN REPUBLICS: PROTOCOL FOR AI-POWERED DECENTRALIZED LEARNING ECONOMIES ON BLOCKCHAIN

A RANDOMIZED, PLACEBO-CONTROLLED, SINGLE-BLINDED CLINICAL TRIAL TO ASSESS SAFETY AND EFFICACY OF CD24FC IN CONTROLLING CARDIOVASCULAR DISEASE RISKS OF HIV-INFECTED PATIENTS

IMPACT AID PROGRAM, TITLE VII, SECTION 7002

IMPACT AID PROGRAM, TITLE VII, SECTION 7002

MULTI-FUNCTIONAL ADAPTIVE BIOMIMETIC HIGH ENERGY-DENSITY BATTERY ENCLOSURE

IMPACT AID PROGRAM, TITLE VII, SECTION 7002

IMPACT AID PROGRAM, TITLE VII, SECTION 7002

IMPACT AID PROGRAM, TITLE VII, SECTION 7002

IMPACT AID PROGRAM, TITLE VII, SECTION 7002

UNKNOWN TITLE

IMPACT AID PROGRAM TITLE VIII SECTION 8002

UNKNOWN TITLE

UNKNOWN TITLE

IMPACT AID PROGRAM TITLE VIII SECTION 8002

DEVELOPING A DIAGNOSTIC BLOOD TEST FOR SARCOIDOSIS

IMPACT AID PROGRAM, TITLE VIII, SECTION 8002

IMPACT AID PROGRAM, TITLE VIII, SECTION 8002

IMPACT AID PROGRAM, TITLE VIII, SECTION 8002

IMPACT AID PROGRAM, TITLE VIII, SECTION 8002

IMPACT AID PROGRAM TITLE VIII SECTION 8002

UNKNOWN TITLE

IMPACT AID PROGRAM, TITLE VIII, SECTION 8002

IMPACT AID PROGRAM, TITLE VIII, SECTION 8002

DOMESTIC WATER GRANTS - REGULAR

CANAL REHABILITATION AND REGULATION PROJECT

NOVEL THERAPEUTICS FOR SEPSIS

TARGETING HOST RESPONSE TO DAMP FOR THERAPY OF RHEUMATOID ARTHRITIS

306A EMERGENCY COMMUNITY WATER ASSISTANCE GRANTS - LIMIT $150,000 - REGULAR

CRRSAA FUNDING

ASSISTANCE TO FIREFIGHTERS GRANT

SECTOR-BASED STRATEGIES

BUSINESS INCUBATOR

TECHNICAL ASSISTANCE AWARD

CHP

RURAL BUSINESS DEVELOPMENT GRANTS - DISASTER (RBDG E DISASTER) GRANTS

MERCADO PACOIMA - LOCALLY GROWN PRODUCE, HARVESTING A CULTURE OF SUSTAINABILITY

TECHNICAL ASSISTANCE AWARD

ST. FRANCOIS COUNTY WILL JOIN WITH JEFFERSON COUNTY AND WASHINGTON COUNTY TO DEVELOP A MASTER PLAN FOR MANAGING THE MULTIPLE SITES CONTAMINATED WITH

REAP RENEWABLE ENERGY SYSTEM (RES) GRANT UNRESTRICTED AMOUNT

CARES ACT

RURAL HOUSING PRESERVATION GRANTS

PURPOSE: THE FAMILY SELF-SUFFICIENCY PROGRAM (FSS) IS GOVERNED BY SECTION 23 OF THE 1937 HOUSING ACT. THE PURPOSE OF FSS AWARDS IS TO FUND THE SALARIES AND FRINGE FOR FSS COORDINATORS, WHO ARE RESPONSIBLE FOR IMPLEMENTING FSS FOR RESIDENTS OF PUBLIC HOUSING, HOUSING CHOICE VOUCHERS (HCV), AND PROJECT-BASED RENTAL ASSISTANCE (PBRA) PROPERTIES. FSS FUNDS APPROXIMATELY 900 PROGRAMS RUN BY PUBLIC HOUSING AUTHORITIES (PHAS) AND PBRA PROPERTY OWNERS ACROSS THE COUNTRY. RENEWAL APPLICANTS ARE PRIORITIZED BY STATUTE.; ACTIVITIES TO BE PERFORMED: FUNDS UNDER FSS GRANTS ARE USED SOLELY TO FUND SALARY AND FRINGE BENEFITS FOR FSS COORDINATORS. RESPONSIBILITIES OF FSS COORDINATORS UNDER THE AWARD INCLUDE, BUT ARE NOT LIMITED TO, ENROLLING, AND MAINTAINING FAMILIES IN THE PROGRAM, WORKING WITH FAMILIES TO PREPARE INDIVIDUAL TRAINING AND SERVICES PLANS (ITSPS), AND BUILDING PARTNERSHIPS WITH EMPLOYERS AND SERVICE PROVIDERS IN THE COMMUNITY. THE REQUIRED NUMBER OF PARTICIPATING FAMILIES THAT A GRANTEE MUST MAINTAIN IS OUTLINED IN THE FUNDING NOTICE AND IS BASED ON THE NUMBER OF COORDINATORS FOR WHICH A GRANTEE RECEIVES FUNDING. GENERALLY, THE GRANTEE MUST HIRE/RETAIN ONE FULL-TIME EQUIVALENT (FTE) FSS PROGRAM COORDINATOR FOR EACH FUNDED POSITION. FOR THE FIRST FULL-TIME FSS COORDINATOR POSITION FUNDED BY HUD, PROGRAMS MUST SERVE AT LEAST 25 PARTICIPATING FAMILIES IN FSS DURING THE PERIOD OF PERFORMANCE (THE CALENDAR YEAR FOLLOWING THE APPROPRIATION), AND THIS NUMBER INCREASES BY 50 FAMILIES FOR EACH ADDITIONAL FUNDED COORDINATOR AFTER THE FIRST.; EXPECTED OUTCOMES: GRANTEES WILL HIRE/RETAIN THE NUMBER OF COORDINATORS FOR WHICH THEY ARE FUNDED. THESE COORDINATORS WILL SERVE AT LEAST THE MINIMUM NUMBER OF PARTICIPANTS REQUIRED BY THE GRANT. OVER THE 5-7 YEARS OF THEIR CONTRACT OF PARTICIPATION, PARTICIPANTS WILL BECOME EMPLOYED OR IMPROVE THEIR EMPLOYMENT AND WAGES AND MEET OTHER INDIVIDUAL GOALS.; INTENDED BENEFICIARIES: THE INTENDED BENEFICIARIES OF FSS ARE FAMILIES CURRENTLY RESIDING IN PUBLIC HOUSING (SECTION 9), FAMILIES CURRENTLY PARTICIPATING IN THE HOUSING CHOICE VOUCHER (SECTION 8) PROGRAM, AND THOSE LIVING IN PROJECT-BASED RENTAL ASSISTANCE (PBRA) PROPERTIES. ; SUBRECIPIENT ACTIVITIES: THE RECIPIENT DOES NOT INTEND TO SUBAWARD FUNDS.

PURPOSE: THE FAMILY SELF-SUFFICIENCY PROGRAM (FSS) IS GOVERNED BY SECTION 23 OF THE 1937 HOUSING ACT. THE PURPOSE OF FSS AWARDS IS TO FUND THE SALARIES AND FRINGE FOR FSS COORDINATORS, WHO ARE RESPONSIBLE FOR IMPLEMENTING FSS FOR RESIDENTS OF PUBLIC HOUSING, HOUSING CHOICE VOUCHERS (HCV), AND PROJECT-BASED RENTAL ASSISTANCE (PBRA) PROPERTIES. FSS FUNDS APPROXIMATELY 900 PROGRAMS RUN BY PUBLIC HOUSING AUTHORITIES (PHAS) AND PBRA PROPERTY OWNERS ACROSS THE COUNTRY. RENEWAL APPLICANTS ARE PRIORITIZED BY STATUTE.; ACTIVITIES TO BE PERFORMED: FUNDS UNDER FSS GRANTS ARE USED SOLELY TO FUND SALARY AND FRINGE BENEFITS FOR FSS COORDINATORS. RESPONSIBILITIES OF FSS COORDINATORS UNDER THE AWARD INCLUDE, BUT ARE NOT LIMITED TO, ENROLLING, AND MAINTAINING FAMILIES IN THE PROGRAM, WORKING WITH FAMILIES TO PREPARE INDIVIDUAL TRAINING AND SERVICES PLANS (ITSPS), AND BUILDING PARTNERSHIPS WITH EMPLOYERS AND SERVICE PROVIDERS IN THE COMMUNITY. THE REQUIRED NUMBER OF PARTICIPATING FAMILIES THAT A GRANTEE MUST MAINTAIN IS OUTLINED IN THE FUNDING NOTICE AND IS BASED ON THE NUMBER OF COORDINATORS FOR WHICH A GRANTEE RECEIVES FUNDING. GENERALLY, THE GRANTEE MUST HIRE/RETAIN ONE FULL-TIME EQUIVALENT (FTE) FSS PROGRAM COORDINATOR FOR EACH FUNDED POSITION. FOR THE FIRST FULL-TIME FSS COORDINATOR POSITION FUNDED BY HUD, PROGRAMS MUST SERVE AT LEAST 25 PARTICIPATING FAMILIES IN FSS DURING THE PERIOD OF PERFORMANCE (THE CALENDAR YEAR FOLLOWING THE APPROPRIATION), AND THIS NUMBER INCREASES BY 50 FAMILIES FOR EACH ADDITIONAL FUNDED COORDINATOR AFTER THE FIRST.; EXPECTED OUTCOMES: GRANTEES WILL HIRE/RETAIN THE NUMBER OF COORDINATORS FOR WHICH THEY ARE FUNDED. THESE COORDINATORS WILL SERVE AT LEAST THE MINIMUM NUMBER OF PARTICIPANTS REQUIRED BY THE GRANT. OVER THE 5-7 YEARS OF THEIR CONTRACT OF PARTICIPATION, PARTICIPANTS WILL BECOME EMPLOYED OR IMPROVE THEIR EMPLOYMENT AND WAGES AND MEET OTHER INDIVIDUAL GOALS.; INTENDED BENEFICIARIES: THE INTENDED BENEFICIARIES OF FSS ARE FAMILIES CURRENTLY RESIDING IN PUBLIC HOUSING (SECTION 9), FAMILIES CURRENTLY PARTICIPATING IN THE HOUSING CHOICE VOUCHER (SECTION 8) PROGRAM, AND THOSE LIVING IN PROJECT-BASED RENTAL ASSISTANCE (PBRA) PROPERTIES. ; SUBRECIPIENT ACTIVITIES: THE RECIPIENT DOES NOT INTEND TO SUBAWARD FUNDS.

FAMILY SELF-SUFFICIENCY PROGRAM

PURPOSE: THE FAMILY SELF-SUFFICIENCY PROGRAM (FSS) IS GOVERNED BY SECTION 306 OF THE ECONOMIC GROWTH, REGULATORY RELIEF, AND CONSUMER PROTECTION ACT (PUBLIC LAW NO: 115-174). THE PURPOSE OF FSS AWARDS IS TO FUND THE SALARIES AND FRINGE FOR FSS COORDINATORS, WHO ARE RESPONSIBLE FOR IMPLEMENTING FSS FOR RESIDENTS OF PUBLIC HOUSING, HOUSING CHOICE VOUCHERS (HCV), AND PROJECT-BASED RENTAL ASSISTANCE (PBRA) PROPERTIES. FSS FUNDS MORE THAN 800 PROGRAMS RUN BY PUBLIC HOUSING AUTHORITIES (PHAS) AND PBRA PROPERTY OWNERS ACROSS THE COUNTRY. RENEWAL APPLICANTS ARE PRIORITIZED BY STATUTE, AND NEW AWARD SELECTION IS MADE BY LOTTERY.; ACTIVITIES TO BE PERFORMED: FUNDS UNDER FSS GRANTS ARE USED SOLELY TO FUND SALARY AND FRINGE BENEFITS FOR FSS COORDINATORS. RESPONSIBILITIES OF FSS COORDINATORS UNDER THE AWARD INCLUDE, BUT ARE NOT LIMITED TO, ENROLLING, AND MAINTAINING THE MINIMUM NUMBER OF FAMILIES IN THE PROGRAM, WORKING WITH FAMILIES TO PREPARE INDIVIDUAL TRAINING AND SERVICES PLANS (ITSPS), AND BUILDING PARTNERSHIPS WITH EMPLOYERS AND SERVICE PROVIDERS IN THE COMMUNITY. THE REQUIRED NUMBER OF PARTICIPATING FAMILIES THAT A PROGRAM MUST MAINTAIN IS OUTLINED IN THE NOTICE OF FUNDING OPPORTUNITY (NOFO) AND IS BASED ON THE NUMBER OF COORDINATORS FOR WHICH A GRANTEE RECEIVES FUNDING. GENERALLY, THE GRANTEE MUST HIRE/RETAIN ONE FULL-TIME EQUIVALENT (FTE) FSS PROGRAM COORDINATOR FOR EACH FUNDED POSITION. FOR THE FIRST FULL-TIME FSS COORDINATOR POSITION FUNDED BY HUD, PROGRAMS MUST SERVE AT LEAST 25 PARTICIPATING FAMILIES IN FSS DURING THE PERIOD OF PERFORMANCE (THE CALENDAR YEAR FOLLOWING THE APPROPRIATION), AND THIS NUMBER INCREASES BY 50 FAMILIES FOR EACH ADDITIONAL FUNDED COORDINATOR AFTER THE FIRST.; EXPECTED OUTCOMES: GRANTEES WILL HIRE/RETAIN THE NUMBER OF COORDINATORS FOR WHICH THEY ARE FUNDED. THESE COORDINATORS WILL SERVE AT LEAST THE MINIMUM NUMBER OF PARTICIPANTS REQUIRED BY THE GRANT. OVER THE 5-7 YEARS OF THEIR CONTRACT OF PARTICIPATION, PARTICIPANTS WILL BECOME EMPLOYED OR IMPROVE THEIR EMPLOYMENT AND WAGES AND MEET OTHER INDIVIDUAL GOALS.; INTENDED BENEFICIARIES: THE INTENDED BENEFICIARIES OF FSS ARE FAMILIES CURRENTLY RESIDING IN PUBLIC HOUSING (SECTION 9), FAMILIES CURRENTLY PARTICIPATING IN THE HOUSING CHOICE VOUCHER (SECTION 8) PROGRAM, AND THOSE LIVING IN PROJECT-BASED RENTAL ASSISTANCE (PBRA) PROPERTIES.; SUBRECIPIENT ACTIVITIES: THE RECIPIENT DOES NOT INTEND TO SUBAWARD FUNDS.

FAMILY SELF-SUFFICIENCY PROGRAM

FAMILY SELF-SUFFICIENCY PROGRAM

RBDG RURAL BUSINESS COOP RURAL ENTERPRISE GRANT

TOURISM DEVELOPMENT

COMMUNITY FACILITY 2019 DISASTER GRANTS - TORNADOES FLOODS OTHER

RURAL BUSINESS ENTERPRISE GRANTS

SEC. 9007 REAP-ENERGY EFFICIENCY IMPROVEMENTS GRANTS (MAN)

REAP RENEWABLE ENERGY SYSTEM (RES) GRANT UNRESTRICTED AMOUNT

FAMILY SELF-SUFFICIENCY PROGRAM

FAMILY SELF-SUFFICIENCY PROGRAM

FAMILY SELF-SUFFICIENCY PROGRAM

FY 2009 RECOVERY ACT JAG PROGRAM

COMMUNITY FACILITIES - ECONOMIC IMPACT INITIATIVE GRANTS

RURAL BUSINESS ENTERPRISE GRANTS

COMMUNITY FACILITIES - ECONOMIC IMPACT INITIATIVE GRANTS

FAMILY SELF-SUFFICIENCY PROGRAM

FAMILY SELF-SUFFICIENCY PROGRAM

FAMILY SELF-SUFFICIENCY PROGRAM

COMMUNITY FACILITY GRANTS

ASSISTANCE TO FIREFIGHTERS GRANTS

RBDG RURAL BUSINESS COOP RURAL ENTERPRISE GRANT

RURAL BUSINESS ENTERPRISE GRANTS

THIS GRANT SUPPORTS THE COSTS INCURRED TO IMPLEMENT MEASURES TO RESPOND TO THE NOVEL CORONAVIRUS 2019 (COVID-19), WHICH MAY INCLUDE WORKPLACE SAFETY, MARKET PIVOTS, RETROFITTING FACILITIES, TRANSPORTATION, WORKER HOUSING, AND MEDICAL EXPENSES. IT PROVIDES NEEDED RELIEF TO THE FOOD PROCESSORS, DISTRIBUTORS, FARMERS MARKETS, AND PRODUCERS FOR THEIR COSTS INCURRED BETWEEN JANUARY 27, 2020, THE DATE UPON WHICH THE PUBLIC HEALTH EMERGENCY WAS DECLARED BY THE U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICE (HHS) UNDER SECTION 319 OF THE PUBLIC HEALTH SERVICE ACT, AND DECEMBER 31, 2021. BENEFICIARIES INCLUDE THE EMPLOYEES OF THE FOOD PROCESSORS, DISTRIBUTORS, FARMERS MARKETS, AND PRODUCERS.

TO SUPPORT MUSEO AL AIRE LIBRE (OPEN AIR MUSEUM), A SERIES OF OUTDOOR URBAN AND PUBLIC ART PROJECTS.

ASSESSMENT AND MITIGATION OF HAWKSBILL CONSUMPTION IN ECUADOR'S JAMBELI ARCHIPELAGO.

UNICOI INVESTIGATIVE UNIT

PURPOSE: TO SUPPORT THE CREATION OF MURALS AT THE COIT ROAD FARMERS MARKET.

TO HELP BRING TO PORTUGAL US PROFESSOR DONALD CASE FOR THE KEY-NOTE SPEECH AT THE IV ENCONTRO IBERICO EDIBCIC AT THE UNIVERSIDADE DE COIMBRA NOVE

AMERICAN THEATER PLAY IN ENGLISH BY STUDENTS OF LYCEE MAGENDIE AMERICAN SECTION BORDEAUX. FOR THE PAST SEVEN YEARS STUDENTS HAVE PREPARED AND PER

GRANT AMENDED TO EXTEND THE GRANT PERIOD UNTIL SEPTEMBER 30 2010. THE CONFERENCE DATES POSTPONED TO AUGUST 2010

LINING OF THE 4B CAANL AND SOLAR POWERED MONITORING STATION

COMMUNITY FACILITY 2019 DISASTER GRANTS - TORNADOES FLOODS OTHER

RENEWABLE ENERGY GRANTS

FY23 FUNDING

DOMESTIC WATER GRANTS - REGULAR

ASSISTANCE TO FIREFIGHTERS GRANT