Centre College Of Kentucky

INSTITUTIONAL USE ACCORDING TO GUIDELINES SET FORTH BY THE DEPARTMENT OF EDUCATION FOR EXPENSES ASSOCIATED WITH THE DISRUPTION OF CAMPUS ACTIVITIES RELATED TO COVID-19.

CENTRE COLLEGE FUNDING CERTIFICATION AND AGREEMENT

RENOVATION OF STUDENT/FACULTY RESEARCH SPACES AT CENTRE COLLEGE

IMPLEMENTING SUICIDE PREVENTION WITH SUPPORT FROM SAMHSA AT CENTRE COLLEGE - WE WILL SERVE UNDERGRADUATES, AGED 17 TO 24, ON OUR RESIDENTIAL CAMPUS. IN ACADEMIC YEAR, 2020-2021,19% OF STUDENTS IN COUNSELING REPORTED SUICIDAL IDEATION. BY FALL 2021, 22.1% REPORTED SUICIDAL IDEATION. THERE WERE 4 KNOWN SUICIDE ATTEMPTS. OUR PROJECT CREATES A ROBUST INFRASTRUCTURE FOR STUDENT SUPPORT, INTENSIFIES SCREENINGS FOR STUDENT MENTAL HEALTH ISSUES, AND TRAINS CAMPUS STAKEHOLDERS USING EVIDENCE-BASED MODELS. APPROXIMATELY 58% OF CENTRE UNDERGRADUATES ARE FROM KENTUCKY. THE RACIAL AND ETHNIC MAKEUP OF THE STUDENT BODY IS 75.98% CAUCASIAN, 6.74% BLACK OR AFRICAN AMERICAN, 7.58% ASIAN/PACIFIC ISLANDER, 4.09% TWO OR MORE RACES, 5.3% UNKNOWN, .23% AMERICAN INDIAN OR ALASKA NATIVE, AND .08% NATIVE HAWAIIAN. 7.4% OF STUDENTS IDENTIFY AS HISPANIC (OF ANY RACE). APPROXIMATELY 11% IDENTIFY AS LGBTQ+ BASED ON ESTIMATES FROM THE CENTRE PRIDE ALLIANCE, A STUDENT ORGANIZATION. ALL STUDENTS AT CENTRE SPEAK ENGLISH PROFICIENTLY, THOUGH IT MAY NOT BE A STUDENT’S FIRST LANGUAGE. NONE OF OUR STUDENTS ARE CURRENTLY U.S. MILITARY VETERANS. FROM A SOCIOECONOMIC PERSPECTIVE, 21% OF OUR CURRENT STUDENTS ARE PELL GRANT ELIGIBLE. FROM A CLINICAL PERSPECTIVE, OUR STUDENTS DEMONSTRATE MENTAL HEALTH ISSUES SUCH AS ANXIETY, DEPRESSION, DISORDERED EATING, SUBSTANCE MISUSE, AND SUICIDAL IDEATION. WE HAVE PARTNERED WITH JED CAMPUS TO IMPLEMENT A 4-YEAR PLAN TO REDUCE SUICIDAL IDEATION AND PREVENT SUICIDE ON OUR CAMPUS. JED’S FRAMEWORK ACTS AS OUR ROADMAP. WITH A GRANT FROM SAMHSA, WE WILL ADDRESS INFRASTRUCTURE GAPS BY HIRING STAFF TO CREATE A STAFFING AND ADMINISTRATIVE INFRASTRUCTURE THAT ENHANCES OUR ABILITY TO ASSESS AND IDENTIFY STUDENTS AT RISK; DEVELOP A CAMPUS-WIDE HEALTH EDUCATION PROGRAM DRAWN FROM EVIDENCE-BASED PRACTICES THAT PROMOTES MENTAL HEALTH AWARENESS, INCREASES HELP-SEEKING BEHAVIOR; AND EFFECTIVELY USES SCREENING TO MORE AT-RISK STUDENTS PRIOR TO CRISIS. PROJECT GOALS AND MEASURABLE OBJECTIVES: - INCREASE THE CAPACITY OF THE CENTRE COMMUNITY TO RECOGNIZE AND RESPOND TO STUDENTS AT RISK OF SUICIDE BY CREATING A STAFFING AND ADMINISTRATIVE INFRASTRUCTURE THAT MAY IMPROVE SUICIDE PREVENTION. O SEVEN OBJECTIVES LISTED IN THE NARRATIVE WILL GUIDE OUR WORK AND MEASURE OUR PROGRESS AND IMPACT. - DEVELOP A CAMPUS-WIDE HEALTH EDUCATION PROGRAM FOR STUDENTS, FACULTY, AND STAFF, DRAWING FROM EVIDENCE-BASED PRACTICES THAT MAY PREVENT SUICIDE, INCREASE MENTAL HEALTH AWARENESS, DECREASE SUBSTANCE MISUSE AND INCREASE HELP-SEEKING BEHAVIOR. 1 O TWELVE OBJECTIVES LISTED IN THE NARRATIVE WILL GUIDE OUR WORK AND MEASURE OUR PROGRESS AND IMPACT. - INCREASE AWARENESS OF AND ACCESS TO ONLINE MENTAL HEALTH RESOURCES INCLUDING MENTAL HEALTH SCREENS THAT MAY INCREASE HELP-SEEKING BEHAVIOR AND PREVENT SUICIDE. O THREE OBJECTIVES LISTED IN THE NARRATIVE WILL GUIDE OUR WORK AND MEASURE OUR PROGRESS AND IMPACT. EACH YEAR, OVER 1,300 PEOPLE WILL BE SERVED. OVER THE 3-YEAR PROJECT WE ESTIMATE SERVING 4,000 UNDERGRADUATES IN TOTAL.

COLLABORATIVE RESEARCH: SYMBIOSIS AND REPERCUSSIONS OF EXTREME ECOLOGICAL SPECIFICITY

COLLABORATIVE RESEARCH: RUI: STRUCTURE-FUNCTION RELATIONSHIPS AND EFFICIENCY OF BACTERIAL FLAGELLAR MOTORS USING COMPUTATIONAL FLUID DYNAMICS AND DIRECTED EVOLUTION EXPERIMENTS -BACTERIA ARE AMONG THE OLDEST ORGANISMS ON EARTH. THROUGH BIOLOGICAL EVOLUTION, MANY BACTERIA HAVE ACQUIRED A BIOMECHANICAL FLAGELLUM CONSISTING OF A HELICAL APPENDAGE THAT IS ROTATED BY A MOLECULAR MOTOR TO MOVE THEM THROUGH THEIR FLUID ENVIRONMENT. FLAGELLAR GENETIC ORGANIZATION, REGULATION, AND STRUCTURE ARE BROADLY CONSERVED ACROSS BACTERIAL SPECIES, AND FLAGELLA PLAY VITAL ROLES IN THE BACTERIAL LIFE CYCLE, INCLUDING IN HOST-MICROBE INTERACTIONS. THUS, UNDERSTANDING BACTERIAL MOTILITY HAS BROAD IMPLICATIONS IN MEDICINE, IN BIOLOGY, AND IN THE DEVELOPMENT OF MICRO-ROBOTIC SWIMMERS. THIS RESEARCH AIMS TO UNDERSTAND HOW THE ENERGY EFFICIENCY OF THE BACTERIAL MOTOR HAS INFLUENCED THE EVOLUTIONARY DEVELOPMENT OF THE BACTERIAL MOTILITY SYSTEM. THE PROJECT WILL CREATE PRECISELY CALIBRATED COMPUTATIONAL TOOLS TO STUDY VARIANTS OF THE MEDICALLY IMPORTANT ORGANISM PSEUDOMONAS AERUGINOSA WITH DIFFERENT MOTOR PROPERTIES. THE ENERGY EFFICIENCY OF EACH VARIANT WILL BE MEASURED AND ASSOCIATED WITH STRUCTURAL CHANGES IN MOTOR COMPONENTS. THE COMPUTATIONAL TOOLS AND A LIBRARY OF THESE MOTOR VARIANTS WILL BE MADE PUBLICLY AVAILABLE SO THAT OTHER RESEARCHERS MAY USE THEM FOR RELATED RESEARCH. THE EXPERIMENTS AND COMPUTATIONS REQUIRED FOR THIS WORK WILL ALL BE CONDUCTED IN TANDEM WITH UNDERGRADUATE STUDENTS, WITH THE GOAL THAT MANY OF THEM, INCLUDING STUDENTS FROM UNDERREPRESENTED BACKGROUNDS, WILL PURSUE CAREERS IN INTERDISCIPLINARY SCIENTIFIC RESEARCH. RECENT WORK HAS UNCOVERED THE MOLECULAR STRUCTURE OF THE STATOR UNIT RESPONSIBLE FOR GENERATING TORQUE IN THE BACTERIAL FLAGELLAR MOTOR. THIS PROJECT AIMS TO CHARACTERIZE THE RELATIONSHIPS BETWEEN SPECIFIC STRUCTURAL PROPERTIES OF THE BACTERIAL STATOR AND ITS ENERGY EFFICIENCY. STRAINS OF P. AERUGINOSA WITH SUBOPTIMAL STATORS WILL BE CREATED AND USED IN DIRECTED EVOLUTION EXPERIMENTS TO SELECT FOR VARIANT STRAINS WITH IMPROVED MOTILITY. QUANTITATIVE MICROSCOPY WILL BE USED TO MEASURE BACTERIAL MOTION AS THEY MOVE THROUGH DIFFERENT FLUID ENVIRONMENTS. EXPERIMENTALLY DETERMINED TRAJECTORIES WILL BE INPUT INTO PRECISELY CALIBRATED COMPUTATIONAL FLUID DYNAMICS SIMULATIONS TO DETERMINE THE ENERGY EFFICIENCY OF THE STATOR. THE DETERMINATION OF SEQUENCE AND STRUCTURAL FEATURES OF EVOLVED STATORS WITH DIFFERENT ENERGY EFFICIENCIES WILL PROVIDE INSIGHTS INTO THE RELATIONSHIP BETWEEN THE MECHANICAL PROPERTIES AND BIOMOLECULAR STRUCTURES OF NANOMOTORS. ADDITIONALLY, TO STUDY HOW THE PRESENCE OF A NEARBY BOUNDARY AFFECTS THE SWIMMING EFFICIENCY OF THE EVOLVED STRAINS, MOTILITY EXPERIMENTS WILL BE PERFORMED NEAR SMOOTH SURFACES AND SURFACES WITH TUNABLE VISCOSITY AND ELECTROSTATIC PROPERTIES. THE SURFACES WILL BE CONSTRUCTED FROM LIPIDS AND PROTEINS TO MIMIC THE ENVIRONMENTS THAT P. AERUGINOSA COMMONLY ENCOUNTERS IN ITS NATURAL ENVIRONMENT AS IT UNDERGOES MOTILE-TO-SESSILE TRANSITIONS. THE CALIBRATION MEASUREMENTS WILL ALLOW OTHER RESEARCHERS TO CREATE ADDITIONAL PRECISELY CALIBRATED COMPUTATIONAL FLUID DYNAMICS MODELS AND DEVELOP SIMILAR COMPUTATIONAL PROBES AS USED IN THIS PROJECT. THE PUBLICLY AVAILABLE LIBRARY OF EVOLVED MOTOR VARIANTS AND THE STRUCTURE-FUNCTION MAP FOR THE STATOR WILL DEEPEN THE UNDERSTANDING OF THE RELATIONSHIP BETWEEN MOTOR PROTEINS AND MOTOR PERFORMANCE. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

PHENOTYPE ANALYSIS OF TYROSINE HYDROXYLASE NEURONS IN RAT AND HUMAN CORTICES

CAPTURING NEW VOICES AND PERSPECTIVES: HUMANITIES PROJECTS AT THE CENTRE COLLEGE LIBRARY DELAYED BY COVID-19 [CENTRE COLLEGE SEEKS TO FUND THE NEW ROLE OF CATALOGING AND METADATA LIBRARIAN IN ITS GRACE DOHERTY LIBRARY, SO THAT OTHER LIBRARY STAFF CAN COMPLETE DELAYED PROJECTS IN THE ARCHIVES AND DIGITAL HUMANITIES RELATED TO CAPTURING NEW VOICES AND PERSPECTIVES. ULTIMATELY, THIS PROJECT WILL MAKE MORE RESOURCES IN THE HUMANITIES SEARCHABLE AND ACCESSIBLE TO STUDENTS AND SCHOLARS. THE HIRING FOR THIS POSITION WAS DELAYED BY THE PANDEMIC. THIS LED TO A BACKLOG OF WORK AND HINDERED RESEARCH IN THE HUMANITIES FIELDS.] [PURPOSE: TO HIRE AND FUND A NEW CATALOGING AND METADATA LIBRARIAN IN THE CENTRE COLLEGE LIBRARY. ACTIVITIES TO BE PERFORMED: THE COLLEGE WILL HIRE ANEW LIBRARIAN WHO WILL ADDRESS A BACKLOG IN ITS CAMPUS LIBRARY OF OVER 2,150 LOCAL AUTHORS AND 2,544 LOCAL MATERIALS FOR WHICH CATALOGING WAS POSTPONED BECAUSE OF THE NOVEL CORONAVIRUS PANDEMIC. WHEN CATALOGUED, THE NEW LIBRARIAN WILL MAKE THESE MATERIALS SEARCHABLE SO THAT THEY CAN BE USED IN THE COLLEGE?S COURSES AND IN STUDENT AND FACULTY RESEARCH. HAVING THE LIBRARIAN ON HAND WILL FREE OTHER LIBRARY STAFF TO COMPLETE DELAYED HUMANITIES PROJECTS IN THE COLLEGE?S ARCHIVES AND DIGITAL HUMANITIES COLLECTIONS. EXPECTED OUTCOMES: THIS PROJECT WILL MAKE MORE RESOURCES IN THE HUMANITIES ACCESSIBLE AND SEARCHABLE, PARTICULARLY ONES THAT HIGHLIGHT PREVIOUSLY UNDERREPRESENTED VOICES. INTENDED BENEFICIARIES: PRIMARY BENEFICIARIES WILL BE THE RECIPIENT?S APPROXIMATELY 1,400 ENROLLED UNDERGRADUATE STUDENTS. MORE EXPANSIVELY, THE RECIPIENT MAINTAINS A PARTNERSHIP WITH THE KENTUCKY STATE DIGITAL ARCHIVES, AND THROUGH THE WEBSITE OF THOSE ARCHIVES THE COLLECTIONS IN THE RECIPIENT?S LIBRARY ARE ACCESSIBLE GLOBALLY. SUBRECIPIENT ACTIVITIES: THE RECIPIENT DOES NOT INTEND TO SUBAWARD FUNDS.]

COLLABORATIVE RESEARCH: TRANSFORMING ORGANIC CHEMISTRY INSTRUCTION THROUGH FACULTY WORKSHOPS AND A COMMUNITY OF PRACTICE

THIS ACTION APPROVES AN AWARD IN THE AMOUNT OF $24,998 TO CENTRE COLLEGE OF KENTUCKY TO IMPLEMENT A HIGHLY VISIBLE CAMPUS COMPOSTING SYSTEM FROM FOOD

KENTUCKY BLUEGRASS WEEK: SHARING CENTRAL KENTUCKY CULTURE WITH THE YAMAGUCHI PREFECTURE

NEH ENDURING QUESTIONS COURSE ON CITIZENSHIP

FY 2015 SUMMER UNDERGRADUATE RESEARCH FELLOWSHIP -GAITHERSBURG MML/MATSCI/NCNR & MML/CHEMBIO

FY 2017 SUMMER UNDERGRADUATE RESEARCH FELLOWSHIP MATSCI/NCNR

REMEMBERING OUR PAST: PRESERVING THE SOUL OF SECOND STREET THROUGH DIGITAL IMAGES