Prism

NCORP OF THE CAROLINAS (GREENVILLE HEALTH SYSTEM NCORP)

COMMUNITY PROJECT FUNDING/CONGRESSIONALLY DIRECTED SPENDING - CONSTRUCTION - AS PRISMA HEALTH–UPSTATE (PRISMA HEALTH) IS A PRIMARY HEALTH CARE PROVIDER FOR THE MAJORITY OF UPSTATE SOUTH CAROLINA RESIDENTS, MAINTAINING APPROPRIATE CAPACITY AND SERVICES FOR THIS REGION IS CRITICAL. PRISMA HEALTH CAN ACCOMPLISH THIS BY ENSURING THAT THE RIGHT HEALTHCARE IS AVAILABLE IN THE RIGHT SETTINGS. THIS PROJECT WILL CREATE HOSPITAL CAPACITY AND SPACE TO PERFORM ROUTINE OUTPATIENT CARDIOVASCULAR PROCEDURES IN A COST EFFECTIVE AND APPROPRIATE SETTING. ACCORDING TO THE SC DEPARTMENT OF HEALTH AND ENVIRONMENTAL CONTROL (DHEC), HEART DISEASE IS SOUTH CAROLINA’S LEADING CAUSE OF DEATH. 11,385 SOUTH CAROLINIANS DIED FROM HEART DISEASE IN 2020 AND ACCOUNTED FOR 75,886 HOSPITALIZATIONS DURING THAT SAME TIME, WITH TOTAL HOSPITALIZATION CHARGES OF MORE THAN $6.8 BILLION. CURRENTLY THE MAJORITY OF BOTH HIGH AND LOW ACUITY CARDIOVASCULAR PROCEDURES ARE PERFORMED AT PRISMA HEALTH’S GREENVILLE MEMORIAL HOSPITAL (GMH). HOWEVER, RISING HEART DISEASE PREVALENCE, AN AGING POPULATION, AND HIGHER ACUITY HAS LED TO AN INCREASE IN OVERALL HOSPITAL UTILIZATION FOR CARDIAC PATIENTS, PUTTING A SIGNIFICANT CAPACITY CONSTRAINT ON THE GMH FACILITIES. CARDIOVASCULAR OUTPATIENT PROCEDURES IN GREENVILLE COUNTY ARE EXPECTED TO GROW 16% BY 2026 AND 32% BY 2029. AS THE PRIMARY HEALTH SYSTEM IN THE UPSTATE, IT IS IMPERATIVE THAT WE ARE PREPARED TO MEET THIS DEMAND. THE PROJECT CONSISTS OF RENOVATING 4,000 SQUARE FEET AND EXPANDING 4,400 SQUARE FEET OF SPACE ON THE FIRST FLOOR OF PRISMA HEALTH–UPSTATE’S PATEWOOD HOSPITAL, FOR A TOTAL OF 8,400 SQUARE FEET, TO BUILD OUT TWO PROCEDURAL ELECTROPHYSIOLOGY LABS AND A PREP AND RECOVERY AREA. THIS WILL ALLOW PRISMA HEALTH TO SHIFT LOWER RISK CARDIOVASCULAR PROCEDURES FROM PRISMA HEALTH’S GREENVILLE MEMORIAL HOSPITAL (GMH) TO ITS PATEWOOD HOSPITAL AND COMPLEMENT PATEWOOD’S CURRENT SERVICE PORTFOLIO OF OFFERING OUTPATIENT/SHORT-STAY, LOW-RISK SERVICES. THE PROJECT WILL PROVIDE LEADING-EDGE TECHNOLOGY AND ADVANCED TREATMENT MODA LITIES TO ADDRESS THE PUBLIC HEALTH HEART DISEASE CRISIS, WHILE FREEING UP NEEDED SPACE FOR HIGHER ACUITY CARDIOVASCULAR INTERVENTIONS AND TREATMENTS AT GMH. SHIFTING ROUTINE OUTPATIENT PROCEDURES TO PATEWOOD HOSPITAL WILL NOT ONLY CREATE CAPACITY AT GMH BUT WILL OPTIMIZE THE DELIVERY OF CARE BY CREATING THE ABILITY TO ADAPT THE STAFFING LEVELS AT EACH LOCATION TO THE LEVEL OF PROCEDURE COMPLEXITY.

ELIMINATING DISPARITIES IN PERINATAL HEALTH

ELIMINATING DISPARITIES IN PERINATAL HEALTH

GREENVILLE SC CCOP

MODERNIZING ONCOLOGY SERVICES INFRASTRUCTURE FOR ENHANCED HEALTHCARE ACCESS - AS PRISMA HEALTH–UPSTATE (PRISMA HEALTH) IS A PRIMARY HEALTH CARE PROVIDER FOR RESIDENTS THROUGHOUT UPSTATE SOUTH CAROLINA, MAINTAINING APPROPRIATE CANCER TREATMENT CAPACITY AND ACCESS TO MODERN RADIATION ONCOLOGY SERVICES IS CRITICAL. PRISMA HEALTH CAN ACCOMPLISH THIS BY ENSURING PATIENTS HAVE ACCESS TO ADVANCED TREATMENT TECHNOLOGY CLOSE TO HOME. THIS PROJECT WILL MODERNIZE RADIATION ONCOLOGY SERVICES AT THE PRISMA HEALTH CANCER INSTITUTE BY REPLACING AN AGING VARIAN TRILOGY LINEAR ACCELERATOR WITH A NEW VARIAN TRUEBEAM LINEAR ACCELERATOR EQUIPPED WITH HYPERSIGHT IMAGING, RAPID ARC DYNAMIC TREATMENT DELIVERY, AND ALIGNRT SURFACE-GUIDED RADIATION THERAPY TECHNOLOGY. CANCER INCIDENCE CONTINUES TO RISE AS SOUTH CAROLINA’S POPULATION GROWS, THE POPULATION AGES, AND PATIENTS LIVE LONGER FOLLOWING A CANCER DIAGNOSIS. RADIATION THERAPY REMAINS A PRIMARY COMPONENT OF CANCER CARE, WITH MORE THAN HALF OF CANCER PATIENTS RECEIVING RADIATION AT SOME POINT DURING TREATMENT. THE PRISMA HEALTH CANCER INSTITUTE SERVES PATIENTS FROM GREENVILLE COUNTY AND SURROUNDING COMMUNITIES THROUGHOUT THE UPSTATE, MANY OF WHOM TRAVEL SIGNIFICANT DISTANCES FOR SPECIALIZED ONCOLOGY SERVICES. ALTHOUGH THE EXISTING TRILOGY ACCELERATOR CONTINUES TO PROVIDE SAFE, EFFECTIVE, AND GUIDELINE-SUPPORTED TREATMENT, ITS OLDER TECHNOLOGY LIMITS THE NUMBER OF PATIENTS WHO CAN BENEFIT FROM NEWER IMAGING, TREATMENT-PLANNING, AND PATIENT-POSITIONING CAPABILITIES. REPLACING THE SYSTEM IS NECESSARY TO MEET INCREASING DEMAND, REDUCE THE RISK OF EQUIPMENT-RELATED INTERRUPTIONS, AND PRESERVE ACCESS TO ADVANCED CANCER CARE THROUGHOUT THE REGION. THE $5,000,000 PROJECT CONSISTS OF PURCHASING ONE VARIAN TRUEBEAM LINEAR ACCELERATOR SYSTEM AND ONE VISION RT ALIGNRT SURFACE-GUIDED RADIATION THERAPY SYSTEM, INCLUDING APPLICABLE SHIPPING AND TAX, FOR THE PRISMA HEALTH CANCER INSTITUTE AT 900 WEST FARIS ROAD, GREENVILLE, SOUTH CAROLINA. HYPERSIGHT IMAGING WILL IMPROVE VISUALIZATION OF PATIENT ANATOMY IMMEDIATELY BEFORE TREATMENT, ALLOWING CLINICIANS TO CONFIRM TUMOR LOCATION AND PATIENT POSITIONING WITH GREATER PRECISION. RAPID ARC DYNAMIC WILL ALLOW PHYSICIANS, DOSIMETRISTS, AND MEDICAL PHYSICISTS TO DEVELOP HIGHLY CUSTOMIZED TREATMENT PLANS THAT CONFORM RADIATION DOSE TO COMPLEX TUMORS WHILE REDUCING EXPOSURE TO SURROUNDING HEALTHY TISSUES. ALIGNRT WILL CONTINUOUSLY MONITOR PATIENT POSITION DURING TREATMENT USING THREE-DIMENSIONAL SURFACE MAPPING, IMPROVING ACCURACY AND REDUCING THE NEED FOR ADDITIONAL RADIATION-BASED IMAGING. ONCE OPERATING AT FULL CAPACITY, THE NEW SYSTEM HAS THE POTENTIAL TO DELIVER APPROXIMATELY 10,000 RADIATION TREATMENTS ANNUALLY. MORE EFFICIENT TREATMENT DELIVERY WILL CREATE ADDITIONAL APPOINTMENT AVAILABILITY, ALLOW MORE PATIENTS TO BEGIN TREATMENT SOONER, AND EXPAND ACCESS TO SPECIALIZED TREATMENT TECHNIQUES. THE PROJECT WILL ALSO IMPROVE EQUIPMENT RELIABILITY, SYSTEM UPTIME, CYBERSECURITY PROTECTIONS, AND LONG-TERM MANUFACTURER SUPPORT. TOGETHER, THESE IMPROVEMENTS WILL STRENGTHEN PRISMA HEALTH’S RADIATION ONCOLOGY INFRASTRUCTURE, REDUCE TREATMENT INTERRUPTIONS, IMPROVE THE PATIENT EXPERIENCE, AND PROVIDE RESIDENTS THROUGHOUT UPSTATE SOUTH CAROLINA WITH RELIABLE ACCESS TO ADVANCED CANCER TREATMENT FOR THE NEXT DECADE.

HEALTHY START INITIATIVE-ELIMINATING RACIAL/ETHNIC DISPARITIES

SUPPORT VACCINATION AGAINST COVID-19 IN PERU.

RURAL COMMUNITIES OPIOID RESPONSE PROGRAM - MEDICATION ASSISTED TREATMENT ACCESS - ADDRESS: 605 GROVE ROAD, GREENVILLE, SC 29605 PROJECT DIRECTOR NAME: ALAIN LITWIN, MD, MPH, MS CONTACT PHONE NUMBERS (VOICE, FAX): (864) 430-0911 EMAIL ADDRESS: ALAIN.LITWIN@PRISMAHEALTH.ORG WEBSITE ADDRESS: WWW.PRISMAHEALTH.ORG LIST ALL GRANT PROGRAM FUNDS REQUESTED IN THE APPLICATION: $3,000,000 PROJECT POWER AIMS TO REDUCE MORBIDITY AND MORTALITY RELATED TO SUBSTANCE USE DISORDER (SUD), INCLUDING OPIOID AND ALCOHOL USE DISORDERS, IN RURAL COMMUNITIES OF SOUTH CAROLINA (SC). THE PROJECT WILL UTILIZE HEALTHCARE NAVIGATORS, NURSE PRACTITIONERS, PEER SUPPORT SPECIALISTS AND COMMUNITY PARTNERSHIPS TO EXPAND ACCESS TO MEDICATION-ASSISTED TREATMENT (MAT) AND OTHER EVIDENCE-BASED INTERVENTIONS AND TREATMENTS FOR OPIOID USE DISORDER (OUD) FOR PEOPLE LIVING WITH OUD IN FOUR SC COUNTIES (ABBEVILLE, GREENWOOD, LAURENS AND OCONEE). WE WILL INCREASE TREATMENT CAPACITY THROUGH THE INTRODUCTION OF MOBILE HEALTH CLINICS AND LINK ORGANIZATIONS WITH CURRENT CAPACITY TO ADDRESS THE GAPS IN MAT SERVICES. THE OVERARCHING GOAL OF THIS PROJECT IS TO EXPAND/ENHANCE ACCESS TO MAT BY INCREASING THE NUMBER OF INDIVIDUALS WITH OUD RECEIVING MAT AND PROVIDING SERVICES TO SUPPORT DECREASED ILLICIT SUBSTANCE USE AND PRESCRIPTION OPIOID MISUSE. WITHIN ABBEVILLE, GREENWOOD, LAURENS AND OCONEE COUNTIES, SERVICES WILL BE TARGETED SPECIFICALLY TO INCLUDE PEOPLE LIVING IN RURAL AREAS, AS WELL AS UN- AND UNDER-INSURED INDIVIDUALS, THOSE WITHOUT ACCESS TO TRANSPORTATION, AND/OR FACING OTHER SOCIO-ECONOMIC OR STIGMA-RELATED BARRIERS. THE GOAL AND OBJECTIVES OF THE PROJECT ALIGN WITH THE STATEMENT OF NEED WHICH SHOWS NEGATIVE SOCIAL DETERMINANTS OF HEALTH (SDOH) AND A LACK OF ACCESSIBLE MAT SERVICES FOR THE TARGET POPULATION THROUGHOUT THE FOUR-COUNTY CATCHMENT AREA. THE PROJECT TEAM WILL FOCUS ON LINKING PATIENTS TO CARE IN CLOSE PHYSICAL PROXIMITY TO THEIR LOCATION; ADDRESSING SDOH BY SCREENING FOR SPECIFIC BARRIERS TO TREATMENT, INCLUDING LACK OF TRANSPORTATION, AND THEN WORKI NG TO OVERCOME THOSE BARRIERS; FACILITATING WARM HANDOFFS; AND EXPEDITING INTAKES TO GET PEOPLE ON MAT. THE NURSE PRACTITIONERS WILL IDENTIFY AND SUPPORT A NETWORK OF MAT PROVIDERS, LEVERAGING THE PROPOSED 11 NEW ACCESS POINTS, TO INCREASE ACCESS AND REDUCE TRANSPORTATION BARRIERS TO PATIENTS. TO MAKE THE TARGET POPULATION AWARE OF THE MOBILE CLINIC AND THE SERVICES PROVIDED, THE POWER PROJECT TEAM WILL USE THE FOLLOWING STRATEGIES: 1) ENGAGE AND COLLABORATE WITH COMMUNITY LEADERS AND OTHER COMMUNITY ORGANIZATIONS ON OUTREACH, COMMUNICATION AND MARKETING CAMPAIGNS; 2) SEND TEAMS LED BY INDIVIDUALS TRUSTED BY THE TARGET POPULATION DIRECTLY TO ENCAMPMENTS AND OTHER AREAS FREQUENTED BY THE TARGET POPULATION; AND, 3) PROMOTE THE NEW ACCESS POINTS VIA SOCIAL MEDIA AND WORD OF MOUTH CAMPAIGNS IN THE TARGET COUNTIES. BY BRINGING SERVICES DIRECTLY TO THE TARGET COUNTIES, PRISMA HEALTH–UPSTATE CAN BETTER MEET THE NEEDS OF UNDERSERVED AND HIGH-RISK POPULATIONS THAT ARE CURRENTLY WITHOUT ACCESS TO SCREENING AND MAT VIA TRADITIONAL ACCESS POINTS AND ACHIEVE BROADER SERVICE COVERAGE ACROSS AT-RISK POPULATIONS.

THE CAROLINA SURVIVOR CLINIC (CSC)

STRENGTHENING HEALTHCARE INFECTION PREVENTION AND CONTROL AND

COMPREHENSIVE HIGH-IMPACT HIV PREVENTION PROGRAMS FOR COMMUNITY-BASED ORGANIZATIONS - THE SOUTHWEST CENTER FOR HIV/AIDS (SWC) WILL IMPLEMENT A COMPREHENSIVE HIGH-IMPACT HIV PREVENTION PROGRAM IN MARICOPA COUNTY, ARIZONA TARGETED TOWARD HISPANIC/LATINO MEN WHO HAVE SEX WITH MEN (MSM) AGES 13-49, A POPULATION DISPROPORTIONATELY AFFECTED BY ARIZONA?S HIV EPIDEMIC. SWC WILL SUBCONTRACT WITH ONE-N-TEN, AN ORGANIZATION THAT SERVES LGBTQ+ YOUTH, TO SUPPLEMENT SWC?S SERVICES AND REACH INDIVIDUALS UNDER AGE 18. THIS PROJECT WILL HELP INDIVIDUALS AT ALL STAGES OF THE HIV CARE CONTINUUM. SWC?S PS21-2102 PROGRAM WILL DIAGNOSE NEW HIV INFECTIONS; TREAT HIV QUICKLY AND EFFECTIVELY; PREVENT NEW HIV CASES; AND RESPOND QUICKLY TO EMERGING HIV CLUSTERS. THESE EFFORTS WILL HELP THE US DEPARTMENT OF HEALTH AND HUMAN SERVICES REACH ITS GOAL OF REDUCING NEW HIV INFECTIONS BY 75% IN 5 YEARS AND BY 90% BY 2030. THE PROJECT WILL ADDRESS THE NATIONAL HIV EPIDEMIC BY REDUCING NEW INFECTIONS, INCREASING ACCESS TO CARE, AND PROMOTING HEALTH EQUITY FOR PERSONS LIVING WITH HIV OR AT RISK OF HIV INFECTION.THE PURPOSE OF THIS PROJECT IS TO IMPROVE LONG TERM HEALTH OUTCOMES FOR ARIZONANS VULNERABLE TO HIV INFECTION AND UPSET THE STATUS QUO OF THE HIV EPIDEMIC THROUGH HIGH IMPACT HIV PREVENTION ACTIVITIES, INCLUDING: PROVIDING HIV TESTING TO COMMUNITY MEMBERS USING CLINICAL, DRIVE THRU, OUTREACH, AND MAIL ORDER STRATEGIES; LINKING INDIVIDUALS TO SWC?S CLINICIANS FOR HIV MEDICAL CARE, PREP, AND NPEP USING RAPID START PROTOCOLS THAT CONNECT CLIENTS TO PROVIDERS AS QUICKLY AS POSSIBLE; NAVIGATING CLIENTS TO ESSENTIAL SUPPORT SERVICES THAT HELP THEM ACHIEVE VIRAL SUPPRESSION OR ADHERE TO PREP; OPERATING A SAFE SPACE WHERE INDIVIDUALS CAN BUILD COMMUNITY AND ENGAGE IN HIV PREVENTION PROGRAMMING; PARTICIPATING IN OUTREACH AND CONDOM DISTRIBUTION EVENTS THROUGHOUT MARICOPA COUNTY; AND BUILDING PARTNERSHIPS WITH COMMUNITY ORGANIZATIONS AND HEALTH INFRASTRUCTURE, INCLUDING THE ARIZONA DEPARTMENT OF HEALTH SERVICES, RYAN WHITE PART A, AND THE MARICOPA COUNTY DEPARTMENT OF P UBLIC HEALTH. BY THE END OF THE PROJECT ON JUNE 30, 2026, SWC WILL HAVE ACHIEVED THE FOLLOWING OUTCOMES: (1) INCREASED THE NUMBER OF PERSONS WHO KNOW THEIR HIV STATUS BY CONDUCTING 9,000 HIV TESTS AND IDENTIFYING 90 NEWLY DIAGNOSED HIV-POSITIVE INDIVIDUALS (1%); (2) INCREASED THE NUMBER OF INDIVIDUALS RECEIVING INTEGRATED SCREENING BY CONDUCTING 6,300 HIV TESTS (70%) IN WHICH THE CLIENT IS PROVIDED SCREENING FOR SEXUALLY TRANSMITTED INFECTIONS (STIS) (SYPHILIS, GONORRHEA, CHLAMYDIA), VIRAL HEPATITIS, AND/OR TB; (3) INCREASED RECEIPT OF HIV MEDICAL CARE AND ANTIRETROVIRAL THERAPY (ART) AMONG PERSONS NEWLY DIAGNOSED WITH HIV BY LINKING 81 NEWLY DIAGNOSED HIV-POSITIVE INDIVIDUALS (90%) TO MEDICAL CARE WITHIN 30 DAYS OF DIAGNOSIS; (4) INCREASED RECEIPT OF HIV MEDICAL CARE AND ART AMONG PERSONS PREVIOUSLY DIAGNOSED WITH HIV BY IDENTIFYING 20 PREVIOUSLY DIAGNOSED, NOT-IN-CARE, HIV-POSITIVE INDIVIDUALS AND RE-ENGAGING 18 (90%) OF THEM IN MEDICAL CARE WITHIN 30 DAYS; (5) INCREASED ACCESS TO PARTNER SERVICES BY REFERRING 90 NEWLY AND 20 PREVIOUSLY DIAGNOSED HIV-POSITIVE INDIVIDUALS (100%) TO PARTNER SERVICES; (6) INCREASED ACCESS TO PREP BY REFERRING 6,712 (75%) OF THOSE WITH HIV-NEGATIVE TEST RESULTS TO PREP NAVIGATION SERVICES; AND (7) INCREASED AVAILABILITY OF CONDOMS BY DISTRIBUTING 250,000 CONDOMS AND ENSURING ALL PROGRAM PARTICIPANTS ARE OFFERED THEM. SWC WILL EMPLOY INNOVATIVE STRATEGIES AND TECHNIQUES TO ACHIEVE THESE OUTCOMES AND WILL CONTINUOUSLY ADAPT THE PROGRAM TO RESPOND TO THE NEEDS OF THE TARGET POPULATION.

SOUTHWEST CENTER WAYS TO SCALE UP PREVENTION (SWC WSUP) PROJECT - SOUTHWEST CENTER WAYS TO SCALE UP PREVENTION (SWC WSUP) PROJECT WILL PROVIDE AFFIRMING, STIGMA- AND DISCRIMINATION-FREE HIV AND STI PREVENTION AND LINKAGE TO CARE SERVICES FOR FOUR (4) PRIORITY POPULATIONS AND THREE (3) GROUPS OF INTEREST DISPROPORTIONATELY IMPACTED BY THE SYNDEMIC OF HIV/STIS AND FACING HEALTH DISPARITIES IN MARICOPA COUNTY, AZ, A DESIGNATED ENDING THE HIV EPIDEMIC IN THE U.S. (EHE) PRIORITY JURISDICTION. HISTORICALLY AND HOLISTICALLY SOUTHWEST CENTER’S OUTPATIENT SEXUAL HEALTH CLINIC AND EXPERIENCED STAFF CONTINUE TO ADDRESS THE SYNDEMIC OF HIV/STI, VIRAL HEPATITIS, HIGH-RISK SUBSTANCE USE, AND SDOH THAT IMPACT HEALTH DISPARITIES/INEQUITIES FACED BY OUR PRIORITY POPULATIONS AND GROUPS OF INTEREST AS FOLLOWS: 1) MSM, ESPECIALLY OF COLOR; 2) YOUTH (AGES 13 TO 34), ESPECIALLY OF COLOR; 3) GENDER EXPANSIVE PERSONS (E.G., TRANSGENDER, NONBINARY, TWO-SPIRIT, ETC.); 4) INDIVIDUALS WHO USE/HAVE USED SUBSTANCES/DRUGS; AND GROUPS OF INTEREST A) PERSONS OF COLOR; B) PERSONS EXPERIENCING MENTAL HEALTH CHALLENGES; AND C) PERSONS EXPERIENCING HOUSING INSTABILITY/HOMELESSNESS. OUR PROJECT UTILIZES EVIDENCE-BASED/ EVIDENCE-INFORMED (EB/EI) APPROACHES TO ADDRESS BARRIERS TO ACCESS FOR HIV/STI PREVENTION CARE SERVICES. WITH A DUEL-PRONG APPROACH FOR STRATEGY A ACTIVITIES TO STRENGTHEN CLINIC INFRASTRUCTURE AND B ACTIVITIES DESIGNED TO FOSTER STRATEGIC PARTNERSHIPS, SWC IDENTIFIED FIVE (5) GAPS 1) CARE TEAM MEETINGS, 2) PATIENT EXPERIENCE COACH, 3) EMR INFRASTRUCTURE, 4) CASE MANAGEMENT, AND 5) TRANSPORTATION. SWC WSUP PROJECT SHORT-TERM (ST), INTERMEDIATE-TERM (IT), AND LONG-TERM (LT) OUTCOMES ARE: ST1- ENHANCED ADOPTION OF OPTIMAL SEXUAL HEALTH SERVICES AND CLINIC MODELS FOR THE PROVISION OF QUALITY STI-RELATED CLINICAL CARE. ST2- INCREASED UNDERSTANDING OF AND RESPONSIVENESS TO PATIENTS’ EXPERIENCES, SATISFACTION, AND NEEDS. ST3- INCREASED IDENTIFICATION OF NEW HIV AND STI INFECTIONS AND OF PERSONS WITH HIV WHO ARE OUT OF CARE OR NOT VIRALLY SUPPRESSED. ST4- INCREASED PERSONS ELIGIBLE FOR PREP WHO WERE PRESCRIBED PREP AT THE CLINIC. ST5- INCREASED COLLABORATION AND ENGAGEMENT WITH LOCAL PARTNERS AND COMMUNITY MEMBERS TO INFORM SEXUAL HEALTH SERVICE DELIVERY, ESPECIALLY PRIORITY POPULATIONS AFFECTED BY THE HIV/STI SYNDEMIC. IT1- INCREASED RAPID LINKAGE TO HIV MEDICAL CARE FOR PERSONS NEWLY DIAGNOSED WITH HIV IN A SEXUAL HEALTH CLINIC. IT2- INCREASED RECEIPT OF RECOMMENDED, TIMELY STI PREVENTION/TREATMENT INTERVENTIONS FOR PATIENTS AND PARTNERS. IT3- INCREASED RECEIPT OF RAPID ANTIRETROVIRAL THERAPY (ART) IN SEXUAL HEALTH CLINICS FOR PERSONS WITH NEWLY DIAGNOSED HIV. IT4- SUSTAINED COMMUNITY PARTNERSHIPS TO INFORM STRATEGIC EHE PLANNING AND ACTIVITY IMPLEMENTATION. IT5- INCREASED CLINIC CAPACITY TO PROVIDE AFFIRMING, STIGMA- AND DISCRIMINATION-FREE HIV PREVENTION, LINKAGE TO CARE SERVICES. IT6- IMPROVED PATIENT FLOW, INCREASED PATIENT VOLUME AND ABILITY TO SERVE PATIENTS MORE EFFICIENTLY, INCLUDING TIMELY TESTING AND TREATMENT. IT7- INCREASED PREP ADHERENCE AND PERSISTENCE. IT8- INCREASED RE-ENGAGEMENT TO CARE FOR PERSONS WITH HIV WHO ARE OUT OF CARE OR NOT VIRALLY SUPPRESSED. LT1- INCREASED DELIVERY AND UPTAKE OF STIGMA-FREE, QUALITY COMPREHENSIVE SEXUAL HEALTH SERVICES. LT2- INCREASED VIRAL SUPPRESSION AMONG PERSONS WITH HIV. LT3- REDUCED NEW HIV AND STI INFECTIONS. LT4- REDUCED HIV/STI DISPARITIES INCLUDING RACIAL, ETHNIC, GENDER, AND SEXUAL ORIENTATION DISPARITIES. BY UTILIZING EB/EI APPROACHES TO HIV/STI PREVENTION CARE, WE WILL IMPROVE CLINIC EFFICIENCY, ENHANCE EXPRESS SERVICES, IMPROVE CLIENT-CENTERED WHOLE-PERSON CARE, EXPAND EMR WITH PRESS GANEY PATIENT EXPERIENCE PLATFORM, AND IMPLEMENT A RECIPROCAL REFERRAL SYSTEM TO FURTHER FACILITATE TIMELY, COMPASSIONATE CARE. TO GUIDE YEAR 1 EFFORTS, OUR WORK PLAN WILL USE STRATEGY A AND B ACTIVITIES AS WE COLLABORATE WITH THE CDC TO REFINE OUR SWC WSUP WORK PLAN AS IT PROGRESSES TO ENSURE PROJECT EFFORTS UTILIZE A SYNDEMIC APPROACH TO ADDRESS HIV/STIS IN MARICOPA COUNTY.

SOUTHWEST CENTER RECOVERY-ORIENTED CULTURALLY-HOLISTIC PROJECT (SWC-ROCH) - PROJECT NAME: SOUTHWEST CENTER – RECOVERY-ORIENTED CULTURALLY HOLISTIC PROJECT. SOUTHWEST CENTER FOR HIV/AIDS (SWC) IS PREPARED TO STRATEGICALLY OUTREACH AND ENGAGE MEDICALLY UNDERSERVED RACIAL AND ETHNIC INDIVIDUALS AT RISK FOR OR LIVING WITH HIV THROUGH DIVERSE PARTNERS AND COMMUNITY LINKAGES. SWC-ROCH PROJECT WILL EXPAND SERVICES FOR SUBSTANCE USE DISORDERS (SUDS)/MENTAL HEALTH CONDITIONS (COD) OFFERING A STATUS-NEUTRAL APPROACH TO DELIVER WHOLE-PERSON CARE – HIV/VIRAL HEP A&C SERVICES IN MARICOPA COUNTY, AZ. POPULATION SERVED: SWC-ROCH PROJECT SPECIFICALLY TARGETS BLACK MEN, LATINO MEN, LATINO YOUTH/YOUNG ADULTS, ANDBLACK WOMEN AT RISK FOR OR LIVING WITH HIV IN MARICOPA COUNTY, ARIZONA (PRIORITY JURISDICTIONS CDC - ENDING THE HIV EPIDEMIC (EHE). STRATEGIES/INTERVENTIONS: OUTREACH, DIVERSE NETWORK CHICANOS POR LA CAUSA AND ONE-N-TEN, TESTING/ENGAGEMENT, CASE MANAGEMENT, PEER NAVIGATORS, SUD/COD TREATMENT, AND EVIDENCE-BASED PRACTICES/SERVICES (E.G., MATRIX MODEL, SMART RECOVERY, COGNITIVE BEHAVIORAL THERAPY, INTENSIVE OUTPATIENT PROGRAMS). GOALS/MEASURABLE OBJECTIVES: GOAL 1) EXPAND ONGOING EFFORTS IN MARICOPA COUNTY, AZ TO STRATEGICALLY ENGAGE MEDICALLY UNDERSERVED RACIAL AND ETHNIC INDIVIDUALS AT RISK FOR OR LIVING WITH HIV BY OFFERING A STATUS-NEUTRAL APPROACH TO DELIVER WHOLE-PERSON CARE – A SYNDEMIC APPROACH – WEAVING ACCESS TO SUBSTANCE USE DISORDERS (SUDS), MENTAL HEALTH CONDITIONS (COD), HIV, AND VIRAL HEPATITIS SERVICES, AND TREATMENTS. OBJECTIVE 1.1. EXPAND OUTREACH STRATEGIC ACTIVITIES IN DIVERSE UNDERSERVED COMMUNITIES TO ENGAGE TARGET POPULATION OFFERING STATUS-NEUTRAL SUDS AND/OR CO-OCCURRING SUDS/COD TREATMENT AND RECOVERY SUPPORT SERVICES AS MEASURED ANNUALLY BY 2 DIVERSE PARTNERSHIPS, 4 OUTREACH ACTIVITIES, 760 UNDUPLICATED CLIENTS, AND 100 REFERRALS FOR SELF-TEST KITS. OBJECTIVE 1.2. EXPAND CAPACITY TO PROVIDE EVIDENCE-BASED SUDS/COD TREATMENT AND RECOVERY SUPPORT SERVICES TARGET POPULATION OFFERING 2 INTENSIVE OUTPATIENT PROGRAMS (IOPS) 1) ADULT IOPS LGBTQIA2S+ AS MEASURED BY 60 ADULTS ANNUALLY SERVED; AND 2) YOUTH IOPS FOR AGES 14-17 AS MEASURED BY 30 YOUTH ANNUALLY SERVED. OBJECTIVE 1.3 PROVIDE EVIDENCE-BASED SUD/COD TREATMENT AND RECOVERY SUPPORT SERVICES FOR TARGET POPULATION AS MEASURED ANNUALLY BY 2,600 OUTPATIENT SERVICES (3 SESSIONS PER WEEK) AND 100 REFERRALS TO VALLEYWISE FDA MEDICATIONS. OBJECTIVE 1.4. OFFER PARTICIPANTS AND THEIR PARTNERS WHO USE DRUGS AND/OR SEXUAL PARTNERS HIV RAPID PRELIM ANTIBODY TESTING RAPID FOURTH-GENERATION HIV TESTING AS MEASURED BY 2,000 HIV TESTS. GOAL 2) SWC AIMS TO REDUCE PREVALENCE OF SUD/COD/HIV/VIRAL HEP A&C INCREASING ACCESS/LINKAGE TO HIV TREATMENT FOR TARGET POPULATION WITH SUDS LIVING WITH HIV. OBJECTIVE 2.1. PROVIDE ON-SITE PRELIM HIV TESTING TO INCREASE LINKAGE WHEN POSITIVE TO CONFIRMATORY TESTING, STATUS-NEUTRAL FOLLOW-UP AS MEASURED ANNUALLY BY 2,000 SCREENINGS/ASSESSMENTS; 250 CLIENTS CONNECTED WITH SUD/COD SERVICES; 20 PRELIMINARY ASSESSMENTS OF CLIENTS CONNECTED TO RYAN WHITE SERVICES; AND 1,000 HEPATITIS B AND C TESTS. OBJECTIVE 2.2. PROVIDE EDUCATION, CASE MANAGEMENT, REFERRALS/ LINKAGES TO PREP SERVICES AS MEASURED BY 300 CLIENTS WITH PREP SERVICES (NEGATIVE HIV) SAME-DAY APPOINTMENTS, 2,000 CLIENTS PREP EDUCATION, AND 50% CLIENTS PREP COMPLIANCE. OBJECTIVE 2.3. PROVIDE EDUCATION, CASE MANAGEMENT, AND REFERRAL/LINKAGES TO PEP SERVICES AS MEASURED BY 55 CLIENTS SAME-DAY APPOINTMENTS WITH SWC PROVIDERS, 55 CLIENTS PEP EDUCATION, AND 55 CLIENTS OFFERED A TRANSITION TO PREP SERVICES. OBJECTIVE 2.4. PROVIDE SUD/COD CERTIFICATIONS FOR EB PRACTICES AND SERVICES INCLUDING MATRIX IOP, SMART RECOVERY AS MEASURED BY COMPLETION OF 2 CERTIFICATION. SWC-ROCH PROJECT WILL PROVIDE 4,300 UNDUPLICATED INDIVIDUALS WITH SERVICES DURING THE 5-YEAR PROJECT PERIOD.

TO REDUCE COMMUNITY VIOLENCE AND RECIDIVISM AND TO ADDRESS INDIVIDUAL RISK AND PROTECTIVE FACTORS FOR VIOLENCE, PRISMA HEALTH-MIDLANDS SEEKS TO DEVELOP AND IMPLEMENT A HOSPITAL-BASED VIOLENCE INTERVENTION PROGRAM (HVIP) AT PRISMA HEALTH RICHLAND HOSPITAL TRAUMA CENTER IN COLUMBIA, SOUTH CAROLINA, IN COLLABORATION WITH COMMUNITY PARTNERS AND USING COMMUNITY MEMBER INPUT. THE HVIP WILL SERVE HIGH-RISK TEENS AND YOUNG ADULTS LIVING IN UNDERSERVED, MARGINALIZED, AND HIGH-CRIME AREAS OF COLUMBIA TREATED AT THE TRAUMA CENTER FOR A VIOLENCE-RELATED INJURY (GUNSHOT WOUND, STABBING, OR ASSAULT). HVIPS ARE AN EVIDENCE-BASED STRATEGY THAT UTILIZES CREDIBLE MESSENGERS TO PROVIDE INTENSIVE CASE MANAGEMENT AND WRAPAROUND SERVICES TO PATIENTS WITH VIOLENCE-RELATED INJURIES. CREDIBLE MESSENGERS, WHO HAVE SHARED EXPERIENCES AND/OR SIMILAR BACKGROUNDS AS PROGRAM PARTICIPANTS, WILL IDENTIFY AND ASSIST PROGRAM PARTICIPANTS TO REDUCE RISK FACTORS FOR VIOLENCE, SUCH AS SUBSTANCE MISUSE, SOCIAL AND EMOTIONAL HEALTH, AND UNEMPLOYMENT. AT THE SAME TIME, PROTECTIVE FACTORS SUCH AS IMMEDIATE SAFETY NEEDS, HOUSING, EDUCATION, EMPLOYMENT, AND DEVELOPMENT OF SOCIAL SKILLS ARE PROMOTED. EVALUATION OF IMPACT AND OUTCOMES OF THE HVIP WILL BE CONDUCTED THROUGH A COMPANION EVALUATION PROPOSAL FROM PRISMA HEALTH-MIDLANDS UNDER THE NIJ FY 2023 COMMUNITY BASED VIOLENCE INTERVENTION AND PREVENTION INITIATIVE RESEARCH, EVALUATION, AND ASSOCIATED TRAINING AND TECHNICAL ASSISTANCE SUPPORT OPPORTUNITY #O-NIJ-2023 1717648, UNDER CATEGORY 3.

HEALTHY START INITIATIVE-ELIMINATING RACIAL/ETHNIC DISPARITIES

PHOENIX AND TUCSON HIGH IMPACT HIV PREVENTION

NEUROIMAGING AIDS FOR TREATMENT OF CNS VISION PATHOLOGY

NEUROIMAGING TOOLS FOR PRESURGICAL BRAIN MAPPING

DISTRIBUTE THE CARES GRANT TO OUR STUDENTS

DISTRIBUTE THE CARES GRANT TO THE INSTITUTION AND ALSO STUDENTS.

IN-SITU TEM HOLDER FOR ULTRAFAST, MULTIMODAL IMAGING

DISTRIBUTE HERRF -2 FUNDS TO OUR STUDENTS.

TIP-BASED FEMTOSECOND MULTIPHOTON SPECTROSCOPY WITH RADIATIVE HEATING

EMERGENCY DEPARTMENT ALTERNATIVES TO OPIOIDS: ADAPTING PROVEN THERAPIES INTO EVERYDAY PRACTICE ACROSS THE SOUTH - PRISMA HEALTH-UPSTATE’S PROJECT ED-ALT WILL DEVELOP AND IMPLEMENT ALTERNATIVES TO OPIOIDS FOR PAIN MANAGEMENT IN EMERGENCY DEPARTMENT (ED) SETTINGS WHILE STILL PROVIDING ADEQUATE PAIN MANAGEMENT IN THE ED. THE PROJECT WILL ADAPT PREVIOUSLY PUBLISHED PROTOCOLS THAT HAVE SUCCESSFULLY UTILIZED MULTIPLE STRATEGIES TO REDUCE OPIATE USE IN THE ED. THE PROGRAM BUILDS ON THESE BY PROVIDING TRAINING AND REAL-TIME SUPPORT OF ED PHYSICIANS TO BETTER ASSESS PATIENTS AND DELIVER THE ENTIRE BREADTH OF THESE PROVEN OPIATE-FREE THERAPIES FOR PAIN MANAGEMENT IN THE ED. THIS PROJECT WILL SERVE A MINIMUM OF 5,000 PATIENTS A YEAR, AND 15,000 OVER 3 YEARS. PROJECT OBJECTIVES ARE TO 1) PROVIDE TRAINING FOR OPIATE FREE PAIN MANAGEMENT STRATEGIES; 2) INITIATE “OPIATE-FREE DAYS” IN THE ED; 3) TRACK OPIATE USE AND FOLLOW-UP CARE/DRUG TESTING, AND 4) DISSEMINATE RESULTS OF THESE BEST PRACTICE INTERVENTIONS. THE PROJECT WILL UTILIZE MULTIPLE MEDICATION AND PROCEDURAL BASED EBPS AS ADAPTED FOR USE IN THE ED, INCLUDING MEDICATION PROTOCOLS, REGIONAL ANESTHESIA, TRANSCUTANEOUS ELECTRICAL NERVE STIMULATION (TENS), AND ACUPUNCTURE. THIS PROJECT IS DESIGNED TO BECOME SELF-SUSTAINING AND ENROLL PATIENTS ON A ROLLING BASIS. IT WILL CREATE A SUSTAINABLE PROGRAM THAT WILL RELY LESS ON THE CONSULT SERVICES AS THE ED PHYSICIANS BECOME COMFORTABLE WITH THE VARIOUS NON-OPIATE MEDICATION AND PROCEDURE PROTOCOLS. AS SUCH, LOCAL PRACTICES WILL BEGIN TO ESTABLISH THESE AS STANDARD FIRST LINE THERAPY AND THE SYSTEM WILL OPERATIONALIZE THESE MULTIDISCIPLINARY TEAMS ORGANICALLY AS THE SYSTEM UNDERSTANDS THE BENEFITS.

BLOUNT COUNTY SUBSTANCE ABUSE PREVENTION ACTION TEAM

THE PARTNERSHIP FOR CHILD NUTRITION IN PERU

FLUID IRRRIGATION TECHNIQUES IN PATIENTS WITH OPEN FRACTURE WOUNDS

HEALTH CARE AND OTHER FACILITIES

SBIR PHASE II: ADAPTIVE EXPERIENTIAL LEARNING PLATFORM TO CLOSE LEARNING GAPS IN SECONDARY ALGEBRA

REFINING DIAGNOSTICS FOR THE IMPROVED DETECTION, SURVEILLANCE, AND STUDY OF THE TRANSMISSION DYNAMICS OF OROPOUCHE - PROJECT SUMMARY THERE IS A KNOWLEDGE GAP REGARDING THE DISEASE BURDEN OF OROPOUCHE (OROV) IN HUMANS BECAUSE OF A LACK OF DIRECT OR STANDARDIZED INDIRECT DIAGNOSTICS (SEROLOGICAL METHODS) APPLIED TO HUMAN OROV SURVEILLANCE IN ENDEMIC AREAS. IN ADDITION, THE IDENTITY OF NON-HUMAN VERTEBRATE HOSTS INVOLVED IN THE SYLVATIC TRANSMISSION CYCLE REMAIN UNCLEAR, AND SYSTEMATIC STUDIES OF OROV VECTORS ARE LIMITED AND OFTEN YIELD CONTRADICTORY FINDINGS. THE LONG-TERM GOAL IS TO IMPROVE THE CONTROL AND LIMIT THE TRANSMISSION OF OROV IN HUMANS. THE OVERALL OBJECTIVE IS TO OBTAIN ABSENT CRITICAL PARAMETERS OF OROV DISEASE TRANSMISSION IN HUMANS, ARTHROPODS, AND NON-HUMAN VERTEBRATE HOSTS. THE CENTRAL HYPOTHESIS IS THAT THESE CRITICAL GAPS OF TRANSMISSION DYNAMICS CAN BE FILLED THROUGH THE USE OF IMPROVED MOLECULAR AND SEROLOGICAL DIAGNOSTIC METHODS IN AN AREA OF HIGH HISTORICAL AND CURRENT OROV DISEASE ENDEMICITY THROUGH THE PERFORMANCE OF THE FOLLOWING THREE SPECIFIC AIMS: 1) TO CHARACTERIZE THE HUMAN BURDEN OF OROV IN A HYPERENDEMIC SETTING THROUGH THE PARALLEL APPLICATION OF GOLD STANDARD AND SIMPLIFIED DIAGNOSTICS; 2) TO SYSTEMATICALLY STUDY NON-HUMAN VERTEBRATE POPULATIONS IN A FRAGMENTED FOREST AREA FOR EVIDENCE OF BOTH ACTIVE AND PRIOR OROV INFECTION; AND 3) TO CONDUCT VECTOR COMPETENCY STUDIES ON LOCAL PURPORTED ARTHROPOD VECTORS FOR OROPOUCHE. TO ADDRESS THE FIRST SPECIFIC AIM, WE WILL CONDUCT HEALTH CARE-BASED SURVEILLANCE TO IDENTIFY A COHORT OF 100 FEBRILE INDIVIDUALS WITH OROV VIREMIA. THIS COHORT OF OROV PARTICIPANTS WILL UNDERGO INTENSIVE SAMPLING TO MEASURE THE DURATION OF VIREMIA, THE KINETICS OF IGM RESPONSE, AND THE RATE OF SEROCONVERSION FOLLOWING INFECTION. PARALLEL TESTING OF RT-PCR AND DIRECT ANTIGEN TESTING WILL EVALUATE A PROTOTYPE OF A RAPID TEST FOR OROV. ADDITIONALLY, PARALLEL TESTING OF IGM BY MAC-ELISA AND A RECOMBINANT ELISA WILL DETERMINE IF A MORE SCALABLE SEROLOGIC TEST IS NON-INFERIOR. FINALLY, A RECOMBINANT ELISA TEST WILL BE COMPARED TO TRADITIONAL PLAQUE REDUCTION NEUTRALIZING TESTS (PRNT) AS WELL AS A NOVEL, SAFE AND SCALABLE NEUTRALIZATION TESTS BASED ON A FLUORESCENT AND LUMINESCENT ASSAY. TO ADDRESS THE SECOND AIM, WE WILL SYSTEMATICALLY CAPTURE AND MEASURE PREVALENCE OF PRIOR INFECTION IN SYLVATIC AND URBAN BIRDS, RODENTS, AND SMALL MAMMALS AND TEST NON- HUMAN PRIMATES AND OTHER SYLVATIC SPECIES RECOVERED THROUGH A PARTNERSHIP WITH THE PERUVIAN ORGANIZATION THAT RECOVERS TRAFFICKED WILD ANIMALS. FOR THE THIRD AIM, WE WILL TEST A SUBSET OF THE LOCAL VECTORS CULICOIDES PARAENSIS, CULICOIDES INSIGNISUS, AEDES SERRATUS, AND MANSONELLA VENEZUELENSIS FOR VECTOR COMPETENCE USING STANDARDIZED MEMBRANE FEEDS OF A LOCAL AND A REFERENCE STRAIN OF OROV. THE PROPOSED RESEARCH IS INNOVATIVE IN USE AND EVALUATION OF A DIRECT ANTIGEN TEST, AND RECOMBINANT AND SCALABLE SERODIAGNOSTICS AND THEIR APPLICATION TO IDENTIFY LOCAL NON-HUMAN VERTEBRATE RESERVOIRS. THE PROPOSED PROJECT IS SIGNIFICANT IN ITS COMPREHENSIVE AND CRITICAL EVALUATION OF SCALABLE, IMPROVED DIAGNOSTIC TESTING FOR BOTH ACUTE DIAGNOSIS AND CONFIRMATORY NEUTRALIZATION ASSAYS, AND THEIR APPLICATION IN AN ENDEMIC SETTING TO ACCURATELY MEASURE DISEASE BURDEN AND UNDERSTAND THE TRANSMISSION DYNAMICS OF THIS EMERGING ARBOVIRAL DISEASE.

FLUID LAVAGE OF OPEN WOUNDS: A MULTICENTER, BLINDED, FACTORIAL TRIAL COMPARING ALTERNATIVE IRRIGATING SOLUTIONS & PRESSURES IN PATIENTS W/ OPEN FRAC

GHS-REACH: A CAREGIVER COACHING INTERVENTION FOR HIGH RISK PATIENT/CAREGIVERS TO EXTEND DEMENTIA CAPABLE SERVICES

THIS ACTION SUPPORTS FOOD ASSISTANCE ACTIVITIES IN PERU BY PRISMA.

VA AWARDS GRANTS TO QUALIFYING ORGANIZATIONS TO PLAN, DEVELOP, MANAGE, AND IMPLEMENT PROGRAMS TO PROVIDE ADAPTIVE SPORTS OPPORTUNITIES FOR DISABLED VETERANS AND DISABLED MEMBERS OF THE ARMED FORCES AS AUTHORIZED UNDER 38 UNITED STATES CODE 521A.

ADAPTIVE RECREATION PROGRAMS TO SUPPORT THE PHYSICAL AND MENTAL HEALTH OF OUR MILITARY WITH A DISABILITY

HEALTH CAREERS OPPORTUNITY PROGRAM (HCOP) SKILLS TRAINING AND HEALTH WORKFORCE DEVELOPMENT OF PAR

ENHANCED MODELLING CAPABILITIES FOR SHORT-PULSE LASER EXPERIMENTS: SHORT-TIME-SCALE LASER DEPOSITION PHYSICS AND CONSISTENT TREATMENT OF DENSE PLASMA EFFECTS ON ATOMIC STRUCTURES AND COLLISIONS

PROJECT TRANSFORM (TEACHING RECOVERY-INFORMED ADDICTION CARE AND NEGATING STIGMA FOR MEDICAL PROFESSIONALS)

WORKFORCE TRAINING

CONGRESSIONALLY-MANDATED HEALTH INFORMATION TECHNOLOGY GRANTS

DENTAL FACULTY LOAN REPAYMENT

DEVELOPMENT OF AN ENHANCED RADIATION PHYSICS TOOLSET FOR MODELING SPECTRAL AND IMAGING SIGNATURES IN THE WARM DENSE MATTER EXPERIMENTS

VA AWARDS GRANTS TO QUALIFYING ORGANIZATIONS TO PLAN, DEVELOP, MANAGE, AND IMPLEMENT PROGRAMS TO PROVIDE ADAPTIVE SPORTS OPPORTUNITIES FOR DISABLED VETERANS AND DISABLED MEMBERS OF THE ARMED FORCES AS AUTHORIZED UNDER 38 UNITED STATES CODE 521A.

HEALTH CARE AND OTHER FACILITIES

ANALYSIS TECHNIQUES FOR DIFFUSION TENSOR IMAGING IN SPINAL CORD DISEASE

DEVELOPMENT OF NON-EQUILIBRIUM EQUATION-OF-STATE AND RADIATION PHYSICS MODELS FOR PHOTOIONIZED PLASMAS AND OTHER RADIATION-DOMINATED SYSTEMS

MAX MARCONI/PRISMA BASIC RESEARCH INC MODELING THE ATMOSPHERE AND IONOSPHERE OF EUROPA THE OBJECTIVE OF THIS PROPOSAL IS, FIRST, TO DEVELOP A NEW C

SEX AND GENDER CURRICULAR ASSESSMENT AND REVISION (SG-CAR) - PROJECT SUMMARY/ABSTRACT THE PROPOSED FACULTY DEVELOPMENT PROJECT AT PRISMA HEALTH-UPSTATE AND THE UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE GREENVILLE (SOMG), SEX AND GENDER CURRICULAR ASSESSMENT AND REVISION (SG-CAR), WILL CREATE INNOVATIVE AND SUSTAINABLE FACULTY DEVELOPMENT MATERIALS FOR USE AT SOMG AND BY OTHER HEALTH PROFESSIONS EDUCATORS ACROSS THE GLOBE, AND IT WILL PROVIDE TRAINING TO FACULTY AND MEDICAL STUDENTS AT SOMG ON HOW TO INCORPORATE SEX AND GENDER INTO MEDICAL EDUCATION. THE OVERALL GOAL OF THIS PROJECT IS TO REDUCE EXISTING FACULTY BARRIERS TO INTEGRATING SEX AND GENDER CONTENT INTO MEDICAL CURRICULA BY PROVIDING FACULTY WITH THE KNOWLEDGE, SKILLS, TOOLS, AND PRACTICAL EXPERIENCE IN THIS WORK. THE PROJECT WILL BE LED BY NATIONAL AND FOUNDATIONAL EXPERTS AT SOMG IN SEX AND GENDER HEALTH, LIFESTYLE MEDICINE, AND MEDICAL EDUCATION CURRICULUM DEVELOPMENT. EACH CO-PI HAS A LONG HISTORY OF DEVELOPING EDUCATIONAL RESOURCES FOR FACULTY DEVELOPMENT WHICH DEMONSTRATES THEIR ABILITY TO SUCCESSFULLY DEVELOP SUCH PROJECTS. SPECIFIC AIM 1 OF THIS PROJECT WILL INCLUDE CREATING AN INTRODUCTORY CURRICULUM THAT WILL BE DEVELOPED FOR CURRENT SOMG FACULTY EMPHASIZING THE IMPORTANCE OF SEX AND GENDER ASPECTS OF HEALTH AND DISEASE. FACULTY WILL BE PROVIDED WITH A SEX AND GENDER CURRICULAR ASSESSMENT INSTRUMENT AND A CURRICULAR REVISION TOOLKIT CREATED BY DR. ALYSON MCGREGOR, ASSOCIATE DEAN AT SOMG, WHICH SHE PILOTED SUCCESSFULLY AT THE WARREN ALPERT MEDICAL SCHOOL OF BROWN UNIVERSITY IN 2021-22. THESE MATERIALS WILL BE REFINED AND VALIDATED AT SOMG AND DISTRIBUTED PUBLICLY THROUGH THE NATIONAL INSTITUTES OF HEALTH AS PART OF THIS PROJECT. IN SPECIFIC AIM 2, FACULTY WHO COMPLETED THE TRAINING IN SPECIFIC AIM 1 WILL LEAD TEAMS OF STUDENTS TO ASSESS THE LIFESTYLE MEDICAL EDUCATION (LMED) CURRICULUM FOR SEX AND GENDER CONTENT USING THE ASSESSMENT INSTRUMENT. LMED IS PRESENTED BY SOMG IN STRATEGIC PARTNERSHIP WITH THE AMERICAN COLLEGE OF LIFESTYLE MEDICINE. IT IS FREELY AVAILABLE TO HEALTH PROFESSIONS FACULTY AND IS CURRENTLY ACCESSED BY 28 U.S. MEDICAL SCHOOLS AND OTHER SCHOOLS WITHIN 57 COUNTRIES. IN SPECIFIC AIM 3, FACULTY WILL LEAD TEAMS OF STUDENTS USING THE TOOLKIT TO REVISE THE LMED CURRICULAR MATERIALS TO INCLUDE SEX AND GENDER CONTENT. THIS WILL ENABLE THESE STUDENTS TO PUBLISH THEIR WORK AND ESTABLISH THEMSELVES AS FUTURE LEADERS IN SEX AND GENDER HEALTH. THE REVISED LMED CURRICULUM WILL BE FREELY AVAILABLE TO EDUCATORS WORLDWIDE THROUGH THE EXISTING LMED WEBSITE. WE ANTICIPATE A BROAD ADOPTION OF THESE FACULTY DEVELOPMENT MATERIALS. WE EXPECT THAT IT WILL TRANSLATE TO IMPROVED SEX AND GENDER SPECIFIC EVIDENCE-BASED CLINICAL CARE FOR WOMEN, THUS REDUCING MORTALITY AND MORBIDITY THAT CURRENTLY EXISTS AMONG WOMEN.

GHS REACH EXPANSION

THIS PROJECT IS FOCUSED ON THE MODELING OF CASSINI H LYMAN-ALPHA DATA. THE OBJECTIVES ARE TO DETERMINE WHETHER THE OBSERVEDASYMMETRY IN THE LARGE SC

HEALTH CARE AND OTHER FACILITIES

SBIR-PHASE I NEW; DEVELOPMENT OF RADIATION AND ATOMIC PHYSICS MODELING TO SUPPORT HIGH-FIDELITY SIMULATION OF HEDLP EXPERIMENTS; JOSEPH MACFARLANE

VETERANS ADAPTIVE SPORTS AND TRAINING TO PROVIDE "ADAPTIVE SPORTS GENERAL" TYPE PROGRAMMING FOR VETERANS WITH DISABILITIES TO INCLUDE PHYSICAL, TBI AND PTS.

PRESURGICAL BRAIN MAPPING WITH FUNCTIONAL CONNECTIVITY MRI

NEUROIMAGING TOOLS FOR PRESURGICAL BRAIN MAPPING

TELEMEDICINE GRANT

EFFECT OF MESOPHILIC ANAEROBIC BIODIGESTION ON TAENIA SOLIUM EGG SURVIVAL, VIABILITY, AND INFECTIVITY: AN APPROACH FOR FUTURE IMPLEMENTATION TO CONTROL HELMINTH INFECTIONS. - PROJECT SUMMARY: MESOPHILIC ANAEROBIC DIGESTION (MAD) IS A COST-EFFECTIVE TECHNOLOGY USED FOR HOUSEHOLD WASTE TREATMENT AND RENEWABLE ENERGY PRODUCTION IN LOW- AND MIDDLE-INCOME COUNTRIES. IT INVOLVES THE USE OF MESOPHILIC ANAEROBIC DIGESTION TO PROCESS FECAL WASTE, PRODUCING GAS THAT CAN BE USED AS COOKING FUEL. ADDITIONALLY, THE BIOSOLIDS AND BIOLIQUIDS PRODUCED AS BYPRODUCTS ARE NUTRIENT-RICH AND CAN BE USED AS SOIL AND FOLIAR FERTILIZERS, MAKING MAD SYSTEMS AN ATTRACTIVE OPTION FOR RURAL COMMUNITIES LACKING SANITATION AND ENERGY INFRASTRUCTURE. DESPITE THEIR ADVANTAGES, BIODIGESTERS CAN POSE SIGNIFICANT RISKS TO HUMAN HEALTH. WHILE PREVIOUS STUDIES HAVE REPORTED ADEQUATE BIOSAFETY OF THE EFFLUENTS, THEY HAVE PRIMARILY FOCUSED ON BACTERIAL PATHOGENS, WHICH ARE RELATIVELY EASY TO DESTROY. THE HIGHLY PATHOGENIC HELMINTH SPECIES, SUCH AS TAENIA SOLIUM, WHICH CAN LEAD TO DEVASTATING INFECTIONS OF THE CENTRAL NERVOUS SYSTEM IF THE EGGS ARE INGESTED, HAVE LARGELY BEEN IGNORED. THE TRANSMISSION OF T. SOLIUM PRIMARILY OCCURS IN RURAL AGRICULTURAL REGIONS, WHICH ARE THE SAME REGIONS WHERE MAD SYSTEMS COULD PROVIDE THE GREATEST SANITATION AND ECONOMIC BENEFITS. THERE IS AN URGENT NEED TO DETERMINE WHETHER MAD SYSTEMS DESTROY T. SOLIUM EGGS AND, IF NOT, HOW TO OPTIMIZE EGG KILLING. TO THIS END, EXPERIMENTS WILL BE CONDUCTED TO EVALUATE THE SURVIVAL AND VIABILITY OF EGGS WITH INCREMENTAL DURATION OF EXPOSURE TO THE MAD SYSTEM. THE INFECTIOUSNESS OF EGGS WILL BE EVALUATED BY FEEDING THEM TO PIGS AND CONDUCTING NECROPSIES TO DETECT THE PRESENCE OF PARASITE CYSTS IN MUSCLE TISSUE. THE MAIN FUTURE GOAL IS TO MODIFY THE MAD SYSTEMS TO MAXIMIZE EGG KILLING AND THEN EVALUATE THESE SYSTEMS IN A COMMUNITY SETTING AS AN INTERVENTION TO CONTROL HELMINTHS. IF SUCCESSFUL, THIS SYSTEM WILL NOT ONLY IMPROVE HYGIENE IN RURAL ENDEMIC AREAS BUT ALSO POSITIVELY IMPACT THE ENVIRONMENT BY REDUCING THE USE OF FIREWOOD AS COOKING FUEL AND DECREASING INDOOR SMOKE THAT AFFECTS LUNG HEALTH, PARTICULARLY AMONG WOMEN. MOST OF MY RESEARCH IS RELATED TO EVALUATING THE TRANSMISSION DYNAMICS OF T. SOLIUM. IN RECENT YEARS, WE HAVE LEARNED ABOUT THE BEHAVIOR OF THIS PARASITE IN ENDEMIC AREAS SUCH AS THE NORTHERN AND HIGHLAND REGIONS OF PERU AND HAVE DEVELOPED TRANSMISSION MODELS THAT HELP US UNDERSTAND HOW THIS PARASITE CAN RETURN TO PREVIOUS LEVELS AFTER INTERVENTIONS THAT CANNOT BE APPLIED PERMANENTLY. IN GENERAL, MY INTEREST AS AN EARLY CAREER RESEARCHER IS TO ASSESS THE IMPACT OF DISEASES BOTH IN SILICO AND IN THE FIELD AND TO FOCUS SCARCE RESOURCES ON DEVELOPING INTERVENTIONS WITH HIGH PUBLIC HEALTH IMPACT.

HEALTHY TOMORROWS PARTNERSHIP FOR CHILDREN PROGRAM

SBIR PHASE I: VIRTUAL REALITY PLATFORM TO ADVANCE K-16 MATH & PHYSICS PROFICIENCY

ARRA - EQUIPMENT TO ENHANCE TRAINING FOR HEALTH PROFESSIONALS

PRISMS, A NOVEL IMMERSIVE LEARNING PLATFORM TO INCREASE PROFICIENCY ON BOTTLENECK TOPICS IN SECONDARY STEM - PROJECT SUMMARY/ ABSTRACT PRISMS OF REALITY SEEKS TO DEVELOP AND ASSESS THE IMPACT AND FEASIBILITY OF AN IMMERSIVE VIRTUAL REALITY (IVR) LEARNING PLATFORM THAT TARGETS HIGH-LEVERAGE PAIN POINTS IN THE SECONDARY MATH AND SCIENCE CURRICULUM TO SUPPORT A MORE DIVERSE AND WELL-EQUIPPED HEALTHCARE WORKFORCE. OUR PLATFORM ENGAGES STUDENTS IN SELF-DIRECTED SCIENTIFIC INQUIRY USING COMPELLING REAL WORLD CONTEXTS THAT DEVELOP EMPIRICAL DECISION-MAKING SKILLS WITH REGARDS TO KEY ISSUES IN PUBLIC HEALTH. IN PHASE I, WE WILL DESIGN AN IVR LEARNING MODULE FOR HIGH SCHOOL ALGEBRA THAT EMPHASIZES HOW MATHEMATICAL MODELING OF ULTRAVIOLET RAYS USING TRIGONOMETRIC FUNCTIONS CAN BE APPLIED TO REASON QUANTITATIVELY ABOUT THE RISKS POSED BY OZONE DEPLETION, WHICH LED TO THE 1987 MONTREAL PROTOCOL. IN THE FACE OF EVER CHANGING CLIMATE CHANGE REGULATIONS, OUR MODULE WILL ENSURE STUDENTS ARE CAPABLE OF FLEXIBLY APPLYING QUANTITATIVE MODELS IN SUPPORT OF POLICIES THAT ADVANCE PUBLIC HEALTH OUTCOMES WHILE IMPROVING PROFICIENCY ON MATH AND SCIENCE SKILLS THAT PRECLUDE SO MANY FROM CONTINUING THEIR EDUCATION IN STEM, SPECIFICALLY IN THE MEDICAL FIELDS. THERE IS EVIDENCE THAT IVR INCREASES MOTIVATION AND ENGAGEMENT, BUT APPLICATIONS IN LEARNING THAT EMPIRICALLY IMPROVE STUDENT OUTCOMES HAVE PROVEN TO BE ELUSIVE. THEREFORE, THE DEVELOPMENT OF A PEDAGOGICAL FRAMEWORK IN IVR THAT LEADS TO ENDURING UNDERSTANDING AND INCREASED ACHIEVEMENT WILL BE GROUND-BREAKING FOR STEM TEACHING AND LEARNING. OUR PLATFORM EMPLOYS CONSTRUCTIVIST, GAMIFIED NARRATIVES THAT FOSTER “HANDS ON” STUDENT DISCOVERY AND 3D SENSE-MAKING OF NATURAL PHENOMENA AND MATHEMATICAL MODELS TIED TO PUBLIC HEALTH ISSUES. THROUGH HOLISTIC DATA COLLECTION AND ANALYTICS, OUR TEACHER-FACING LEARNING MANAGEMENT SYSTEM WILL TRACK EACH STUDENT’S CONCEPTUAL PROGRESS AND PROVIDE INDIVIDUALIZED FEEDBACK. IF SUCCESSFUL, PRISMS’ PLATFORM WILL NOT ONLY TRANSFORM THE STUDENT EXPERIENCE AND ACHIEVEMENT, BUT WILL PROVIDE A MODEL OF HOW PROGRESSIVE PEDAGOGICAL PRACTICES CAN BE ACTUALIZED THROUGH IVR TO YIELD MEANINGFUL STUDENT OUTCOMES. TO DEVELOP THE PLATFORM, IN PHASE I PRISMS WILL A) DESIGN A ROBUST GAME-BASED PEDAGOGICAL FRAMEWORK THAT HARNESSES INNOVATIVE FEATURES UNIQUE TO VR TO CULTIVATE DEEP CONCEPTUAL FLEXIBILITY AND ABSTRACT REASONING SKILLS BASED ON AUTHENTIC REAL WORLD PROBLEMS; B) EXPLORE EFFECTIVE VR FUNCTIONALITIES, EXPERIENCE DESIGN, AND DEVELOPMENT TECHNIQUES FOR HIGH QUALITY IMPLEMENTATION USING THE COST-EFFECTIVE OCULUS QUEST; C) IMPLEMENT A TEACHER-FACING LEARNING MANAGEMENT SYSTEM THAT WILL PROVIDE TEACHERS DATA-DRIVEN INSIGHTS ABOUT STUDENT LEARNING IN ORDER TO SUPPORT INDIVIDUALIZED FEEDBACK AND INTERVENTION; AND D) EVALUATE PRODUCTIVE USER EXPERIENCE & EMPIRICALLY MEASURE OUR PLATFORM’S IMPACT ON LEARNING OUTCOMES IN AUTHENTIC CLASSROOM SETTINGS.

TREATMENT OF WAVYLEAF GRASS AT SEVERAL SITES

ROGER C. PEACE ADAPTIVE SPORTS OUTREACH

ADAPTIVE SPORTS PROGRAMS FOR DISABLED VETERANS AND DISABLED MEMBERS OF THE ARMED FORCES RCP ADAPTIVE SPORTS OUTREACH

ADVANCED VISUALIZATION TECHNIQUES FOR FUNCTIONAL IMAGERY IN NEURODEVICE SURGICAL

DEVELOPMENT OF ION STOPPING MODELS FOR HED PLASMAS USING UNIFIED SELF-CONSISTENT FIELD MODELS AND SELF-CONSISTENT ELECTRON DISTRIBUTIONS

SBIR PHASE I: NICKEL-BASED PRINTABLE METAL ELECTRODES ON FLEXIBLE SUBSTRATES

HEALTH CARE AND OTHER FACILITIES

PREVENTING INFECTION BY SURFACE MODIFICATION OF ORTHOPAEDIC FRACTURE FIXATION IMPLANTS FOR IMPROVED LIMB SALVAGE OUTCOMES

DEVELOPMENT OF NOVEL THERAPEUTICS FOR NEGLECTED TROPICAL DISEASE LEISHMANIASIS

PRISM ASSOCIACION BENEFICA OCEAN FREIGHT CHARGES ASSOCIATED WITH STRATEGIC OBJECTIVE NO. 4

RENEWABLE ENERGY GRANTS

PROVIDING ADAPTIVE SPORT ACTIVITIES DESIGNED TO ENHANCE THE REHABILITATIVE AND THERAPEUTIC HEALTH OF VETERANS AND SERVICEMEMBERS

SBIR PHASE I: THE POTENTIAL FOR HOLOGRAPHIC PLANAR CONCENTRATOR MODULES TO ENHANCE POWER FROM CIGS THIN FILM PHOTOVOLTAIC CELLS

GRANTS FOR ADAPTIVE SPORTS PROGRAMS FOR DISABLED VETERANS AND DISABLED MEMBERS OF THE ARMED FORCES.

TO CONDUCT WORKSHOP INTEGRATING THE FUNDAMENTALS OF EMOTIONAL INTELLIGENCE, ENTREPRENEURSHIP AND COMMUNITY DEVELOPMENT WITH A GOAL TO ACTIVATE A GENERATION OF EMERGING LEADERS THROUGHOUT SERBIA.

REAP RENEWABLE ENERGY SYSTEM (RES) GRANT UNRESTRICTED AMOUNT

DENTAL FACULTY LOAN REPAYMENT

GRANTS FOR ADAPTIVE SPORTS PROGRAMS FOR DISABLED VETERANS AND DISABLED MEMBERS OF THE ARMED FORCES.

ASSIST PRISMA IN THE CONSOLIDATION, SUSTAINABILITY, AND EXPANSION OF THE CAC LOCATED IN "LOS OLIVOS".

ADAPTIVE SPORTS ACTIVITIES FOR DISABLED VETERANS & DISABLED SERVICEMEMBERS

A CROSS-CULTURAL LEADERSHIP DEVELOPMENT PROGRAM. FELLOWS WILL PARTICIPATE IN A YEAR-LONG PROGRAM DESIGNED TO DRIVE CIVIC AND ECONOMIC ENGAGEMENT WHILE CULTIVATING MEANINGFUL INTERNATIONAL RELATIONSHIPS IN OUR NEXT GENERATION OF SOCIAL CHANGE LEADERS.

BLOUNT COUNTY SUBSTANCE ABUSE PREVENTION ACTION TEAM

NCD TRAINING IN CVD,PULMONARY AND OBESITY IN PERU

"THE ATMOSPHERE AND IONOSPHERE OF EUROPA"

PURPOSE: TO SUPPORT A COMMISSIONING, PERFORMANCE, AND RECORDING PROJECT OF NEW WORKS FOR SAXOPHONE QUARTET AND SOLO GUITAR.

PURPOSE: TO SUPPORT A COMPOSITION RESIDENCY AND PERFORMANCE PROJECT.

PURPOSE: TO SUPPORT A COMMISSIONING PERFORMANCE AND RECORDING PROJECT.

PURPOSE: TO SUPPORT THE COMMISSION AND PERFORMANCE OF A NEW WORK IN CELEBRATION OF AMERICAS 250TH ANNIVERSARY.

PURPOSE: TO SUPPORT A PROGRAM OF MUSICAL WORKS CELEBRATING NAT KING COLE AS PART OF AMERICA250.

TO PROMOTE AND DEVELOP CONTEMPORARY DANCE IN PANAMA. USING DANCE AS A TOOL FOR SOCIAL CHANGE AND INCLUSION.

TO SUPPORT SELF PORTRAIT UNFINISHED (A CENTO) A CO-COMMISSIONING AND PERFORMANCE PROJECT WITH CHAMBER CHOIR THE CROSSING FEATURING A NEW WORK FOR SAXOPHONE QUARTET AND CHAMBER CHOIR BY COMPOSER MARTIN BRESNICK.

TO SUPPORT A COMMISSIONING AND PERFORMANCE PROJECT FEATURING NEW WORKS FOR SAXOPHONE QUARTET BY COMPOSERS HANNAH KENDALL AND MARCOS BALTER.

TO SUPPORT HERITAGE/EVOLUTION INITIATIVE COMMISSIONS AND PREMIERES.

PROMOTE AND DEVELOP ART AND CULTURE THROUGH CONTEMPORARY DANCE IN PANAMA. TO CONTRIBUTE TO THE EDUCATION OF PANAMANIAN DANCERS.

TO SUPPORT A COMMISSIONING PERFORMANCE AND RECORDING PROJECT.

TO SUPPORT A COMMISSIONING PERFORMANCE AND RECORDING PROJECT.

TO SUPPORT A COMMISSIONING AND PERFORMANCE PROJECT.

TO SUPPORT A COMMISSIONING AND PERFORMANCE PROJECT.

TO SUPPORT A RECORDING PROJECT OF AMERICAN CHAMBER WORKS FOR SAXOPHONES.

TO SUPPORT A RECORDING PROJECT OF AMERICAN CHAMBER WORKS FOR SAXOPHONES.

THIS GRANT WILL ALLOW FUNDACION PRISMA DANZA TO COORDINATE PRISMA LAB, DANCE AND THEATER MASTERCLASSES FOR AT-RISK COMMUNITIES.

SUDDEN UNEXPECTED INFANT DEATH (SUID) AND SUDDEN DEATH IN THE YOUNG (SDY) CASE REGISTRY

DEOBLIGATION

HEALTH CAREERS OPPORTUNITY PROGRAM (HCOP) ? SKILLS TRAINING AND HEALTH WORKFORCE DEVELOPMENT OF PAR