Tem Foundation Inc

HEALTH CENTER CLUSTER

KEYSTONE BEACON COMMUNITY: PROPOSAL FOR A RURAL COMMUNITY-WIDE MEDICAL HOME

NORTH DAKOTA CREATE (CUSTOMIZING INTEGRATED EMPLOYMENT AVAILABLE TO EVERYONE) JOURNEY TO INCLUSION PROGRAM (ND CJI)

OP EARLY INTERVENTION SVCS W/RESPECT TO HIV DISEASE

OP EARLY INTERVENTION SVCS W/RESPECT TO HIV DISEASE

RYAN WHITE TITLE IV WOMEN, INFANTS, CHILDREN, YOUTH AND AFFECTED FAMILY MEMBERS AIDS HEALTHCARE

EMR-LINKED BIOBANK FOR TRANSLATIONAL GENOMICS

NORTH DAKOTA SCHOOL PSYCHOLOGY SERVICE PROFESSIONAL DEMONSTRATION GRANT (ND SP SERVICE GRANT)

OPTIMALLY CHANGING THE MAP FOR TEEN PREGNANCY PREVENTION IN SPARTANBURG

GEISINGER EGENONIC MEDICINE (GEM) PROGRAM

RYAN WHITE TITLE IV WOMEN, INFANTS, CHILDREN, YOUTH AND AFFECTED FAMILY MEMBERS AIDS HEALTHCARE

MINOT STATE UNIVERSITY, OPEID 00299400 CARES ACT: HIGHER EDUCATION EMERGENCY RELIEF FUND-INSTITUTIONAL PORTION

DIMENSIONAL ANALYSIS OF DEVELOPMENTAL BRAIN DISORDERS USING AN ONLINE, GENOME-FIRST APPROACH

COOPERATIVE AGREEMENT TO SUPPORT NAVIGATORS IN FEDERALLY-FACILITATED EXCHANGES

GEISINGER CLINICAL ONCOLOGY PROGRAM

NORTH DAKOTA CENTER FOR PERSONS WITH DISABILITIES, UNIVERSITY CENTER FOR EXCELLENCE ON DEVELOPMENTAL DISABILITIES CORE GRANT 2022

UNIVERSITY CENTER OF EXCELLENCE ON DEVELOPMENTAL DISABILITIES CORE GRANT 2017

COMPUTATIONAL MODELING OF TUMOR BURDEN BY CT TO ADVANCE CANCER THERAPEUTICS

TBX3-REGULATED ALTERNATIVE RNA PROCESSING IN CARDIAC CONDUCTION SYSTEM DEVELOPMENT

NATURAL HISTORY OF STRESS, URGE AND MIXED URINARY INCONTINENCE IN WOMEN

RYAN WHITE TITLE IV PROGRAM

STRATEGIC PARTNERSHIPS IN NORTHERN VIRGINIA TO INCREASE HIV DIAGNOSIS,TREATMENT, PREVENTION, AND RESPONSE AMONG HIGH-RISK HETEROSEXUAL BLACK, LATINX, AND IMMIGRANT IDENTIFIED POPULATIONS - PROJECT ABSTRACT SUMMARYPURPOSEINOVA JUNIPER PROGRAM (IJP) WILL PARTNER WITH NEIGHBORHOOD HEALTH (NH) TO PROVIDE OUTREACH, TESTING, LINKAGE, AND ENGAGEMENT SERVICES FOCUSED ON HIGH-RISK HETEROSEXUALS WITHIN THE BLACK/AFRICAN AMERICAN, LATINX, AND IMMIGRANT COMMUNITIES OF NORTHERN VIRGINIA. IJP AND NH HAVE LOCATION IN ALL AREAS OF THE REGION, WHICH INCLUDES THE COUNTIES OF FAIRFAX, LOUDOUN, PRINCE WILLIAM, AND ARLINGTON AND THE CITY OF ALEXANDRIA. IN ORDER TO GAIN TRUST, ENGAGEMENT, AND OVERCOME BARRIERS TO CARE, PROGRAM SERVICES WILL BE PRIMARILY DELIVERED BY OUTREACH WORKERS HIRED FROM THESE COMMUNITIES WITH SIMILAR LIFE EXPERIENCES TO THE CLIENTS THEY SERVE.OUTCOMESIJP AND NH TOGETHER WILL ACHIEVE BOTH SHORT/INTERMEDIATE AND LONG TERM OUTCOMES IN EACH OF THE STRATEGIES OUTLINED IN THE ENDING THE EPIDEMIC PLAN. DIAGNOSE SHORT/INTERMEDIATE TERM: INCREASE THE NUMBER OF PERSONS AWARE OF THEIR HIV STATUS, INFORMED OF CARE SERVICES, AND ABLE TO ACCESS INTEGRATING SCREENINGSLONG TERM: INCREASE CULTURAL AWARENESS OF HIV/STD TESTING AND HIV CARE OPTIONS REDUCE STIGMA REGARDING SEXUAL HEALTH CARE, DECREASED MORBIDITY DUE TO LATE SCREENINGTREATSHORT/INTERMEDIATE TERM: INCREASE RECEIPT OF HIV MEDICAL CARE AND TREATMENT BY THE NEWLY DIAGNOSED AND THOSE NOT IN CARE, INCREASED ACCESS TO PARTNER SERVICES AND PREVENTION AND ESSENTIAL SUPPORT SERVICESLONG TERM: REDUCED COMMUNITY VIRAL LOAD, INCREASED LINKAGE TO CULTURALLY COMPETENT SERVICES, REDUCED TIME FROM DIAGNOSIS TO CARE, INCREASED WELL-BEING AMONG PEOPLE LIVING WITH HIV/AIDSPREVENTSHORT/INTERMEDIATE TERM: INCREASE ACCESS TO PREP AND CONDOMS AMONG HIGH-RISK INDIVIDUALSLONG TERM: INCREASED SEXUAL AND OVERALL HEALTH LITERACY AND REDUCED MISINFORMATION; INCREASED COMMUNITY AWARENESS OF AND ACCESS TO PREP, PEP, AND HIV/STD TESTING; INCREASED PROVIDER COMPETENCY REGARDING BEHAVIORS AND TRENDSRESPONDSHORT/INTERMEDIATE TERM: INCREASED HEALTH DEPARTMENT AND COMMUNITY ENGAGEMENT FOR CLUSTER DETECTION AND RESPONSEL ONG TERM: IMPROVED COMMUNITY RESPONSE TO HIV TRANSMISSION CLUSTERS AND OUTBREAKSOVER THE COURSE OF THIS FIVE YEAR PROJECT, THE PROGRAM SEEKS TO REDUCE NEW HIV INFECTIONS, IMPROVE HEALTH OUTCOMES AND REDUCE MORBIDITY AND MORTALITY AMONG PEOPLE LIVING WITH HIV, AND IMPROVE THE OVERALL HEALTH STATUS OF HIGH-RISK HETEROSEXUAL BLACK/AFRICAN AMERICAN, LATINX, AND IMMIGRANT COMMUNITIES IN NORTHERN VIRGINIA.

OPTIMUM OB-TXA: OPTIMAL TIMING, ROUTE AND DOSE OF TRANEXAMIC ACID PRIOR TO UMBILICAL CORD CLAMP FOR POSTPARTUM HEMORRHAGE PREVENTION - PROJECT SUMMARY THE PRIMARY GOAL OF THIS PROPOSAL IS TO FILL CRITICAL GAPS RELATED TO TIMING, ROUTE AND DOSE OF TRANEXAMIC ACID (TXA) IN PREVENTION OF POSTPARTUM HEMORRHAGE (PPH) TO MAXIMIZE MATERNAL BENEFIT WHILE MINIMIZING FETAL-NEONATAL AND MATERNAL RISKS. WITH MY CLINICAL BACKGROUND IN MATERNAL-FETAL MEDICINE, RESEARCH EXPERIENCES IN EPIDEMIOLOGIC AND TRANSLATIONAL COAGULATION METHODS, AND PRIOR PRELIMINARY DATA, I HAVE THE EXPERTISE AND STRONG SCIENTIFIC PREMISE TO SUCCESSFULLY COMPLETE THESE AIMS. THE PROPOSED INNOVATIVE STUDY FOCUSES ON THREE UNIQUE SUBPOPULATIONS (VAGINAL DELIVERY, CESAREAN DELIVERY, MORBID OBESITY) AND HAS THREE ROUTES OF TXA ADMINISTRATION (INTRAVENOUS OVER 2 MINUTES, INTRAVENOUS OVER 10 MINUTES AND INTRAMUSCULAR) IMMEDIATELY PRIOR TO CHILDBIRTH. NEONATAL EXPOSURE WILL BE ASSESSED THROUGH TXA CONCENTRATIONS IN UMBILICAL CORD BLOOD AND BREAST MILK, AS WELL AS CLINICAL OUTCOMES AT DELIVERY, 2 WEEKS AND 6 WEEKS POSTPARTUM. THE SPECIFIC AIMS ARE AS FOLLOWS: 1A) DETERMINE THE OPTIMAL TIMING, ROUTE AND DOSE OF PROPHYLACTIC TXA FOR PREVENTION OF PPH 1B) DETERMINE NEONATAL EXPOSURE TO TXA THROUGH TRANSPLACENTAL TRANSFER AND BREAST MILK WHEN TXA IS ADMINISTERED PRE-CORD CLAMP, AND 2) CHARACTERIZE PROTHROMBOTIC AND FIBRINOLYTIC BIOMARKERS IN MATERNAL CIRCULATION FOLLOWING TXA. THE INNOVATIVE NATURE OF THIS GRANT IS MULTIFOLD: A) REPURPOSING AN INEXPENSIVE GENERIC DRUG TO ADDRESS DISPARITIES IN OBSTETRIC HEMORRHAGE; B) EXPLORING RAPID ADMINISTRATION VIA IM AND 2MIN INFUSION TO IMPROVE ACCESS IN LOW RESOURCE SETTINGS; C) PRE-CORD CLAMP TXA ADMINISTRATION AS A NOVEL APPROACH NOT YET CONSIDERED IN LARGE OBSTETRIC CLINICAL TRIALS; D) REFINEMENT OF DOSING IN UNIQUE SUBPOPULATIONS (MORBIDLY OBESE, VAGINAL DELIVERY); E) BIOMARKER SAFETY INCLUDING A NO DRUG GROUP AND F) A ROBUST TEAM OF MULTIDISCIPLINARY EXPERTS WITH REGIONAL AND INTERNATIONAL EXPERTISE. SPECIFICALLY, TEAM MEMBERS HAVE EXPERTISE IN CLINICAL PHARMACOLOGY, NEONATAL MEDICINE, LAB MEDICINE, THROMBOSIS AND HEMOSTASIS, CLINICAL TRIALS IN PREGNANT WOMEN AND NEWBORNS, PHARMACOMETRICS AND EPIDEMIOLOGY/BIOSTATISTICS. I HAVE AN IDEAL WORKING ENVIRONMENT, ROOTED IN THE CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE PARTNERING GW AND CHILDREN’S NATIONAL HOSPITAL BUT ALSO EXTENDED THROUGH SUPPLEMENTAL SITES AT UNIVERSITY OF MARYLAND CENTER FOR TRANSLATIONAL MEDICINE AND UNIVERSITY OF NORTH CAROLINA COAGULATION LAB. IN SUMMARY, THIS PROPOSAL SETS FORTH AIMS THAT ARE SIGNIFICANT, INNOVATIVE, FEASIBLE, AND WILL HELP THE OBSTETRIC COMMUNITY BETTER UNDERSTAND HOW PERIPARTUM HEMOSTASIS CAN BE OPTIMIZED USING TXA WHILE BEING SURE TO MINIMIZE FETAL/NEONATAL RISKS. ULTIMATELY, OUR WORK WILL ANSWER IMPORTANT QUESTIONS THAT ARE PART OF THE SOLUTION FOR HOW TO PREVENT MATERNAL MORBIDITY AND MORTALITY FOR THE 140 MILLION WOMEN WORLDWIDE THAT GIVE BIRTH EACH YEAR.

EXPLORING THE ROLE OF DYSSYNCHRONY IN PEDIATRIC HEART DISEASE WITH MRI

AN INTEGRATED APPROACH TO STUDY GPCR VARIANTS ASSOCIATED WITH COMPLEX DISEASES

THE ROLE OF FGF8 DURING CARDIOVASCULAR DEVELOPMENT

UNIVERSAL NEWBORN HEARING SCREENING

ND INCLUSIVE MODEL PATHWAYS FOR COLLEGE AND CAREER TRAINING CONSORTIUM (IMPCCT) AT MINOT STATE UNIVERSITY

ROLE OF P67PHOX IN MYOCARDIAL HYPERTROPHY

COMPREHENSIVE HIGH-IMPACT HIV PREVENTION PROGRAM FOR YOUNG MEN OF COLOR WHO HAVE SEX WITH MEN

ANE - NURSE PRACTITIONER RESIDENCY PROGRAM

RURAL COMMUNITIES OPIOID RESPONSE PROGRAM ? MENTAL AND BEHAVIORAL HEALTH - 1. PROJECT TITLE: TAHOE FOREST HEALTH SYSTEM BEHAVIORAL HEALTH AND SUBSTANCE USE TREATMENT EXPANSION 2. REQUESTED AWARD AMOUNT: $489,839 PER YEAR 3. APPLICANT ORGANIZATION NAME: TAHOE FOREST HEALTH SYSTEM FOUNDATION 4. APPLICANT ORGANIZATION ADDRESS 11075 DONNER PASS ROAD, TRUCKEE, CA 96161-0442 5. APPLICANT ORGANIZATION FACILITY TYPE (E.G., RURAL HEALTH CLINIC, CRITICAL ACCESS HOSPITAL, TRIBE/TRIBAL ORGANIZATION, HEALTH SYSTEM, INSTITUTE OF HIGHER LEARNING, COMMUNITY-BASED ORGANIZATION, FOUNDATION, RURAL HEALTH NETWORK, ETC.): HEALTH SYSTEM INCLUDING TWO CRITICAL ACCESS HOSPITALS, AND RURAL HEALTH CLINICS SPANNING TWO STATES 6. PROJECT DIRECTOR NAME AND TITLE (SHOULD BE THE SAME INDIVIDUAL DESIGNATED IN BOX8F OF THE SF-424 APPLICATION FORM) CLAIRE DA LUZ, SUBSTANCE USE NAVIGATOR 7. PROJECT DIRECTOR CONTACT INFORMATION (PHONE AND EMAIL) 530-582-3298, CDALUZ@THFD.COM 8. DATA COORDINATOR NAME AND TITLE: ASHLEY VIGANO, GRANTS BILLING COORDINATOR 9. DATA COORDINATOR CONTACT INFORMATION (PHONE AND EMAIL) 530-582-6496 AVIGANO@TFHD.COM 10. EIN/DUNS NUMBER EXCEPTION REQUEST IN ATTACHMENT 8? (Y/N) - NOTE: HRSA RESERVES THE RIGHT TO DEEM APPLICATIONS THAT PROVIDE INSUFFICIENT INFORMATION IN ATTACHMENT 8, OR ARE NEARLY IDENTICAL IN CONTENT, TO BE INELIGIBLE. IN THIS INSTANCE, ASSUMING ALL OTHER ELIGIBILITY CRITERIA ARE MET, HRSA WILL ONLY ACCEPT THE LAST SUBMITTED APPLICATION ASSOCIATED WITH THE EIN OR DUNS NUMBER. NO 11. HOW THE APPLICANT FIRST LEARNED ABOUT THE FUNDING OPPORTUNITY HRSA-22-061 10 (SELECT ONE: STATE OFFICE OF RURAL HEALTH, HRSA NEWS RELEASE, GRANTS.GOV, HRSA PROJECT OFFICER, HRSA WEBSITE, TECHNICAL ASSISTANCE PROVIDER, STATE/LOCAL HEALTH DEPARTMENT) WWW.GRANTS.GOV 12. NUMBER OF CONSORTIUM MEMBERS & LIST OF CONSORTIUM MEMBERS (INCLUDING THE APPLICANT ORGANIZATION) : 4 MEMBERS; TAHOE FOREST HEALTH SYSTEM, SIERRA COMMUNITY HOUSE, PLACER AND NEVADA COUNTIES, GATEWAY MOUNTAIN CENTER 13. IS THE APPLICANT ORGANIZATION A PREVIOUS OR CURRENT RCORP AWARD RECIPIENT OR CONSORTIUM MEMBER? IF YES, SPECIFY: FY18, FY19, AND/OR FY20 RCORP- PLANNING; FY19 RCORP-MAT EXPANSION; FY19, FY20, FY21 RCORP- IMPLEMENTATION, FY20 RCORP-NEONATAL ABSTINENCE PROGRAM, FY21 RCORP- PSYCHOSTIMULANT SUPPORT NO 14. INDICATE IF APPLICANT ORGANIZATION INTENDS TO APPLY FOR FY22 RCORP- IMPLEMENTATION? (Y/N) NO 15. DOES THE TARGET SERVICE AREA OVERLAP WITH THE SERVICE AREAS OF THE NORTHERN BORDER REGIONAL COMMISSION, THE DELTA REGIONAL AUTHORITY, OR THE APPALACHIAN REGIONAL COMMISSION? (INDICATE Y/N AND SPECIFY) NO 16. RCORP-BHS TARGET SERVICE AREA (MUST BE EXCLUSIVELY RURAL, AS DEFINED BY THE RURAL HEALTH GRANTS ELIGIBILITY ANALYZER): A. FULLY RURAL COUNTIES: PROVIDE THE COUNTY NAME AND STATE: NEVADA COUNTY, CALIFORNIA B. PARTIALLY-RURAL COUNTIES: PROVIDE COUNTY NAME, STATE, AND THE RURAL CENSUS TRACT (LIST OF RURAL CENSUS TRACTS) PLACER COUNTY, CA CENSUS TRACTS 06122011, 06122014, 06120107, 06120106, 06120105, 06120104, 061222, 061221, 061223, 061202. WASHOE COUNTY, NEVADA CENSUS TRACTS 0313308, 0313306, 0313305, 0313307. 17. BRIEF DESCRIPTION OF THE TARGET POPULATION. INDICATE APPROXIMATELY WHAT PERCENTAGE (IF ANY) OF THE TARGET POPULATION IS NATIVE AMERICAN, AND, IF APPLICABLE, PROVIDE 2-3 SENTENCES REGARDING HOW THIS PROJECT SPECIFICALLY TARGETS TRIBAL POPULATIONS THE TARGET POPULATION IS EXCLUSIVELY RURAL IN THE SIERRA NEVADA MOUNTAINS AND SPAN A 3,500 MILE REMOTE AND ISOLATED SERVICE AREA. THE MAJORITY OF THE TARGET POPULATION IS WHITE WITH THE NEXT MOST POPULOUS ETHNICITY HISPANIC/LATINO. THE ETHNIC BREAKDOWN OF THE TARGET POPULATION IS 9.8% HISPANIC/LATINO AND 90.2% NON-HISPANIC/LATINO. APPROXIMATELY 1.3% OF OUR POPULATION IS AMERICAN INDIAN/ALASKAN NATIVE. BRIEF PROJECT DESCRIPTION: THIS PROPOSED PROJECT WOULD INCREASE COMMUNITY MEMBERS’ ACCESS TO SUBSTANCE USE TREATMENT, BEHAVIORAL HEALTH TREATMENT, AND GROUP THERAPY SUPPORT. A LICENSED CLINICAL SOCIAL WORKER

IMPROVING RURAL HEALTHCARE TRANSITIONS THROUGH HEALTH INFORMATION EXCHANGE

ROLE OF AN ALTERNATIVELY SPLICED NUCLEAR VARIANT OF ERBB3 IN THE NERVOUS SYSTEM

TRANSITION AND POSTSECONDARY PROGRAMS FOR STUDENTS WITH INTELLECTUAL DISABILITIES (TPSID)

MOLECULAR AND CELLULAR ANALYSIS OF G PROTEIN FUNCTION

EARLY DETECTION OF HEART FAILURE VIA THE ELECTRONIC HEALTH RECORD IN PRIMARY CARE

NORTH DAKOTA NAVIGATORS: COOPERATIVE AGREEMENT TO SUPPORT NAVIGATORS IN FEDERALLY-FACILITATED EXCHANGES CFDA 93.332 FUNDING OPPORTUNITY CMS-NAV-24-001

PHENOTYPING NET IMMUNE STATE WITH MICRORNAS IN CARDIAC TRANSPLANTATION - CURRENTLY, THERE ARE NO RELIABLE CLINICAL STRATEGIES AVAILABLE TO OPTIMIZE IMMUNOSUPPRESSION LEVELS AFTER HEART TRANSPLANTATION. PATIENT SURVIVAL AFTER HEART TRANSPLANT IS LIMITED TO 12 YEARS AND HAS NOT IMPROVED IN THE PAST TWO DECADES LARGELY ATTRIBUTED TO THE SIDE EFFECTS OF IMMUNOSUPPRESSION. IMMUNOSUPPRESSION IS USED TO PREVENT HEART TRANSPLANT REJECTION, BUT THE PROTECTIVE EFFECTS OF IMMUNOSUPPRESSION ARE OFFSET BY MULTIPLE COMPLICATIONS INCLUDING INFECTION, CHRONIC KIDNEY DISEASE, AND CANCER. THERE IS NO AVAILABLE BIOMARKER AVAILABLE TO ASSESS THE ALLOIMMUNE RESPONSE AFTER TRANSPLANT AND GUIDE TITRATION OF IMMUNOSUPPRESSION. THUS, CONTEMPORARY CLINICAL PRACTICE IS TO WEAN IMMUNOSUPPRESSION WHEN DRUG TOXICITY ARISES OR BASED ON TIME AFTER TRANSPLANT. THROUGH CIRCULATING MICRORNAS, SMALL NON-CODING RNA MOLECULES, WE WILL PREDICT COMPLICATIONS OF OVER- (INFECTION) AND UNDER-IMMUNOSUPPRESSION (REJECTION). WE HYPOTHESIZE THAT CIRCULATING MICRORNAS CAN BE USED TO QUANTIFY THE NET IMMUNE STATE OF HEART TRANSPLANT PATIENTS AND IDENTIFY PATIENTS AT HIGH RISK FOR IMMUNOSUPPRESSION-RELATED COMPLICATIONS. THE SCIENTIFIC AIMS OF THIS STUDY WILL BE ACCOMPLISHED THROUGH SERIAL BLOOD-BASED MICRORNA SEQUENCING AND DEEP CLINICAL PHENOTYPING. WE WILL BUILD ON OUR STRONG PRELIMINARY DATA TO DEVELOP A PANEL OF MICRORNAS THAT PREDICT THESE KEY POST-TRANSPLANT COMPLICATIONS AND CORRELATE WITH VARYING DOSES OR LEVELS OF CONTEMPORARY IMMUNOSUPPRESSION. THIS WORK WILL FORM THE BASIS FOR A NON-INVASIVE, GENOMIC BLOOD TEST THAT CAN BE USED TO MONITOR PATIENTS AFTER HEART TRANSPLANT TO MITIGATE COMPLICATIONS AND ENHANCE LONG-TERM SURVIVAL. THE SCIENTIFIC AIMS OF THIS PROPOSAL WILL BE ACHIEVED THROUGH A PROSPECTIVE, MULTICENTER, MULTIRACIAL COHORT STUDY OF ADULT HEART TRANSPLANT PATIENTS (N=250) ENROLLED AT 8 GEOGRAPHICALLY- AND SOCIOECONOMICALLY DIVERSE TRANSPLANT CENTERS, WITH A HIGH PROPORTION OF BLACK PATIENTS (TARGET ENROLLMENT 30%) AS THESE PATIENTS HAVE WORSE CLINICAL OUTCOMES AFTER TRANSPLANT. THE SPECIFIC AIMS OF THIS PROPOSAL ARE: 1) IDENTIFY CIRCULATING MICRORNAS THAT PREDICT THE RISK OF MAJOR OVER- AND UNDER-IMMUNOSUPPRESSION RELATED ADVERSE EVENTS AFTER HEART TRANSPLANTATION, 2) DETERMINE THE RESPONSE OF THE CIRCULATING MICRORNA TRANSCRIPTOME IN HEART TRANSPLANT PATIENTS TO CHANGES IN IMMUNOSUPPRESSIVE THERAPY, AND 3) DEVELOP AND VALIDATE A CLINICAL MICRORNA SCORE THAT PROVIDES A QUANTITATIVE ASSESSMENT OF THE PATIENT’S NET IMMUNE STATE. THIS STUDY WILL ADDRESS SEVERAL CRITICAL BARRIERS NEEDED TO REDUCE COMPLICATIONS OF IMMUNOSUPPRESSION, ENHANCE PATIENT QUALITY OF LIFE, AND IMPROVE LONG-TERM SURVIVAL. DEVELOPMENT AND VALIDATION OF THIS MICRORNA BIOMARKER PANEL IN THIS STUDY FORMS THE BASIS FOR A NEW BLOOD TEST THAT CAN BE USED TO MANAGE TRANSPLANT PATIENTS. THIS WOULD ALLOW CLINICIANS TO BALANCE THE RISKS OF OVER- AND UNDER-IMMUNOSUPPRESSION TO PERSONALIZE MEDICATIONS AFTER HEART TRANSPLANT. THE PATIENT-SPECIFIC ASSESSMENT OF NET IMMUNE STATE CAN THEN BE EVALUATED IN FUTURE RANDOMIZED, CONTROLLED, CLINICAL TRIALS, WHERE THE MICRORNA PANEL INFORMS THE TITRATION OF IMMUNOSUPPRESSION WITH THE GOAL OF MITIGATING THE ADVERSE EVENT RATE AND ENHANCING PATIENT SURVIVAL. THIS RESEARCH ALSO HAS IMPORTANT IMPLICATIONS FOR OTHER SOLID ORGAN TRANSPLANT POPULATIONS.

CENTERS OF EXCELLENCE

MINOT STATE UNIVERSITY TRIO STUDENT SUPPORT SERVICES - TRADITIONAL PROGRAM

MINOT STATE UNIVERSITY STUDENT TRIO SUPPORT SERVICES PROGRAM FOR STUDENTS WITH DISABILITIES

ND SENIOR MEDICARE PATROL PROJECT, 2018-2023

THE OPTIMAL LOOP DIURETIC: MECHANISTIC INSIGHTS FROM LONGITUDINAL CHANGES IN BLOOD AND URINE PROTEINS TO EXPLAIN EFFICACY AND SAFETY OF TORSEMIDE VS FUROSEMIDE AFTER A HEART FAILURE HOSPITALIZATION

ND SENIOR MEDICARE PATROL

STUDENT SUPPORT SERVICES PROGRAM

STUDENT SUPPORT SERVICES PROGRAM

NORTH DAKOTA EARLY HEARING DETECTION AND INTERVENTION INFORMATION SYSTEM (ND EHDI-IS)

ARP ECONOMIC DEVELOPMENT GRANT FOR RURAL HEALTH CARE FACILITIES

TELEMEDICINE GRANT

VALIDATION OF APF AS A URINARY BIOMARKER FOR INTERSTITIAL CYSTITIS

RURAL HEALTH NETWORK DEVELOPMENT PROGRAM

MORBID OBESITY, BARIATRIC SURGERY, AND KIDNEY FUNCTION

PRE-DOCTORAL TRAINING IN PRIMARY CARE

MULTIDISCIPLINARY STUDY OF RACE APPEARANCE ANCESTRY DISCRIMINATION & PREJUDICE

SEX- AND SMOKING- SPECIFIC DNA METHYLATION SIGNATURES OF CENTRAL ADIPOSITY CHANGE

MICRORNA BIOMARKERS OF ALLOGRAFT REJECTION AND CARDIAC ALLOGRAFT VASCULOPATHY IN CARDIAC TRANSPLANTATION

BRIDGING CARE SUPPORT AND CARE DELIVERY WITH ENGINEERED LOGISTICS AND TECHNOLOGY

"(INTEGRATED CLINICAL INFORMATION SYSTEM COLLABORATION PROJECT-PHASE 3) IMPROVING MANAGEMENT OF PATIENTS THROUGH INNOVATIVE CARE OF DIABETES"

THE HEART FAILURE COLLABORATORY PUBLIC-PRIVATE PARTNERSHIP BETWEEN THE UNITED STATES FOOD AND DRUG ADMINISTRATION, THE INOVA HEART AND VASCULAR INSTITUTE, AND THE HEART FAILURE COMMUNITY

CALCIUM SENSING RECEPTOR AND SCAFFOLDS

SMALL HEALTH CARE PROVIDER QUALITY IMPROVEMENT

TRIO STUDENT SUPPORT SERVICES (SSS) REGULAR PROJECT

RURAL PACE PROVIDER GRANT PROGRAM

BETA/GAMMA SUBUNIT HETEROGENIETY IN G PROTEINS

DESCRIPTION:THIS COOPERATIVE AGREEMENT PROVIDES FUNDING UNDER THE INFRASTRUCTURE INVESTMENT AND JOBS ACT (IIJA) FOR GEISINGER CLINIC TO CONDUCT REMEDIATION ACTIVITIES AS AUTHORIZED BY CERLCA 104(K)(3) IN DICKSON CITY MINING RECLAMATION PROJECT, LOCATED IN DICKSON CITY, PENNSYLVANIA. BROWNFIELDS ARE REAL PROPERTY, THE EXPANSION, DEVELOPMENT OR REUSE OF WHICH MAY BE COMPLICATED BY THE PRESENCE OR POTENTIAL PRESENCE OF A HAZARDOUS SUBSTANCE, POLLUTANT, OR CONTAMINANT. ACTIVITIES:SPECIFICALLY, THIS AGREEMENT WILL PROVIDE FUNDING TO THE RECIPIENT TO CLEAN UP A BROWNFIELD SITE. ADDITIONALLY, THE RECIPIENT WILL COMPETITIVELY PROCURE (AS NEEDED) AND DIRECT A QUALIFIED ENVIRONMENTAL PROFESSIONAL (QEP) TO CONDUCT ENVIRONMENTAL SITE ACTIVITIES, WILL CREATE A COMMUNITY INVOLVEMENT PLAN AND ADMINISTRATIVE RECORD FOR THE SITE, AND WILL REPORT ON INTERIM PROGRESS AND FINAL ACCOMPLISHMENTS BY COMPLETING AND SUBMITTING RELEVANT PORTIONS OF THE PROPERTY PROFILE FORM USING EPA'S ASSESSMENT, CLEANUP AND REDEVELOPMENT EXCHANGE SYSTEM (ACRES). SUBRECIPIENT:NO SUBAWARDS ARE INCLUDED IN THIS ASSISTANCE AGREEMENT.OUTCOMES:FURTHER, THE RECIPIENT WILL REMEDIATE THE DICKSON CITY MINING RECLAMATION BROWNFIELD SITE AND ANTICIPATES HOLDING AT LEAST TWO COMMUNITY MEETINGS, FINALIZING ONE ANALYSIS OF BROWNFIELD CLEANUP ALTERNATIVES (ABCA), AND SUBMITTING SIXTEEN QUARTERLY REPORTS. WORK CONDUCTED UNDER THIS COOPERATIVE AGREEMENT WILL BENEFIT THE RESIDENTS, BUSINESS OWNERS, AND STAKEHOLDERS IN AND NEAR DICKSON CITY, PENNSYLVANIA.

NURSE EDUCATION PRACTICE AND RETENTION

HEALTH CARE AND OTHER FACILITIES

MARCELLUS SHALE DEVELOPMENT, RESPIRATORY & REPRODUCTIVE OUTCOMES IN PENNSYLVANIA

DEVELOPING PTSD RISK ASSESSMENT TOOLS USING THE WORLD TRADE CENTER OUTCOME STUDY

FUNCTIONAL SELECTIVITY IN MC4R SIGNALING

PRECISION MEDICINE AT GEISINGER

THE SCIENTIFIC VALUE OF PREMATURE INFANT BIOSPECIMENS COLLECTION - PROJECT SUMMARY/ABSTRACT THE COMPLEXITIES OF HETEROGENEITY, STRATIFICATION, AND STAGING OF SEPSIS HAVE CONTRIBUTED TO THE POOR TRANSLATABILITY OF CURRENT MOLECULAR MODELS FOR DIAGNOSIS AND TREATMENT OF HUMAN SEPSIS. THE NATIONAL ADVISORY GENERAL MEDICAL SCIENCES COUNCIL ADVISED USING DISCOVERY APPROACHES TO CHARACTERIZE SEPSIS USING HUMAN BIOSPECIMENS. SEPSIS, A LIFE-THREATENING ORGAN DYSFUNCTION CAUSED BY A DYSREGULATED HOST RESPONSE TO A BACTERIAL, VIRAL, OR FUNGAL INFECTION, IS A MAJOR CAUSE OF DEATH IN PREMATURE (=32 WEEKS) AND LOW BIRTH WEIGHT (= 1500G) INFANTS AND OCCURS IN UP TO 25% OF SUCH INFANTS.1-3 THE ABILITY TO COLLECT MICROBIOME AND TISSUE BIOSPECIMENS LONGITUDINALLY FROM MULTIPLE BODY SITES UNDER EXTREMELY CONTROLLED CIRCUMSTANCES PRIOR TO, DURING, AND THROUGHOUT SEPSIS (CULTURE PROVEN), SEPSIS-LIKE (CULTURE NEGATIVE CRITICAL ILLNESS), AND "NORMAL" GROWING PREMATURE INFANT CONDITIONS WILL ALLOW OUR TEAM TO DETERMINE OPTIMAL SAMPLE COLLECTION, STORAGE, AND PROCESSING PROTOCOLS USING SMALL VOLUME SAMPLES TO ENHANCE SEPSIS RESEARCH RIGOR, AND TO DEVELOP NEW STRATEGIES FOR SEPSIS DETECTION BY DISCERNING PATHWAYS THAT CONTRIBUTE TO THE PATHOPHYSIOLOGY OF SEPSIS IN THE PREMATURE NEONATAL POPULATION. IN THE R21 PHASE WE WILL COLLECT CLINICAL INFORMATION AND STOOL, BLOOD, AND SALIVA SPECIMENS LONGITUDINALLY FROM PRETERM INFANTS (=32 WEEKS AND =1500G) ON DAYS 1, 3, 7, 14, 21, 28, 35, 42, AND 49 OF LIFE, AND ADDITIONALLY DURING SUSPECTED SEPSIS EVENTS. STANDARDIZATION AND DOCUMENTATION OF SAMPLE COLLECTION, STORAGE, AND PROCESSING AND SAMPLE VALIDATION STUDIES WILL ENSURE RIGOR AND REPRODUCIBILITY AND INFORM THE FIELD. IN THE R33 PHASE WE WILL COLLECT SAMPLES FROM 2 CLINICAL SITES PROVIDING A TEST SET FOR MACHINE LEARNING METHODS. UTILITY OF THE NEWLY COLLECTED BIOSPECIMENS AND ASSOCIATED CLINICAL DATA WILL BE DEMONSTRATED BY CONSTRUCTING A MULTI-OMIC NETWORK FOR PREDICTING CAUSAL MECHANISMS FROM GENES/METABOLITES/CLINICAL PARAMETERS DIFFERENTIALLY EXPRESSED BETWEEN CLINICALLY WELL NEONATES AND THOSE WITH CULTURE PROVEN SEPSIS AND CULTURE NEGATIVE SYSTEMIC INFLAMMATORY ILLNESS. WE WILL MAKE ESTABLISH TESTABLE CAUSAL INFERENCES AND PREDICTIVE MODELS OF MICROBIAL/HOST GENE INTERACTIONS AND BIOLOGIC MECHANISMS LEADING TO SEPSIS THAT COULD FORM THE FOUNDATION FOR FUTURE MECHANISTIC STUDIES. OUR TEAM OF NEONATAL PROVIDERS, IMMUNOLOGISTS, SYSTEMS BIOLOGISTS, MICROBIOME SPECIALISTS, AND BIOINFORMATICIANS SUPPORTED BY TWO LARGE LEVEL IV NICUS ARE UNIQUELY POSITIONED TO COLLECT AND ANALYZE BIOSPECIMENS AND CLINICAL DATA BEFORE, DURING, AND AFTER CRITICAL ILLNESS IN PATIENTS WITH EXTREME PREMATURITY.

GEISINGER COMMONWEALTH SCHOOL OF MEDICINE - INSTITUTIONAL PORTION OF THE HIGHER EDUCATION EMERGENCY RELIEF FUND

THERAPEUTIC ERADICATION OF DCIS PROGENITOR CELLS

NORTH DAKOTA DUAL SENSORY PROJECT:

THE CONTRIBUTION OF ANTIBIOTIC EXPOSURE IN THE PRENATAL, PERIPARTUM AND INFANCY PERIOD TO INTESTINAL MICROBIOME PERTURBATIONS AND ASSOCIATION WITH EARLY CHILDHOOD OBESITY.

GEISINGER COMMONWEALTH SCHOOL OF MEDICINE - INSTITUTIONAL PORTION OF THE HIGHER EDUCATION EMERGENCY RELIEF FUND

EXPANDING SANE SERVICES TO VICTIMS OF SEXUAL ASSAULT ON CAMPUS

NORTH DAKOTA DUAL SENSORY PROJECT

GEISINGER COMMONWEALTH SCHOOL OF MEDICINE - HIGHER EDUCATION EMERGENCY RELIEF FUND-FIPSE

RURAL AGING STUDY (GEISINGER) - 1: CONTINUE TO VALIDATE THE RECENTLY DEVELOPED DIET QUALITY SCREENING QUESTIONNAIRE (DQSQ) IN RELATION TO LONGITUDINAL HEALTH OUTCOMES AND MORTALITY AMONG THE 4,009 REMAINING PARTICIPANTS. 1A: TEST CRITERION VALIDITY: A. ASCERTAIN WHETHER LOW DQSQ SCORES PLACE PERSONS OF ADVANCED AGE AT RISK FOR ADVERSE HEALTH OUTCOMES. B. ASCERTAIN WHETHER LOW DQSQ SCORES PLACE PERSONS OF ADVANCED AGE AT RISK FOR INCREASED MORTALITY. 2: CONDUCT COMPREHENSIVE DIETARY ASSESSMENTS OF A REPRESENTATIVE SUBSET OF 200 COMMUNITY-DWELLING PARTICIPANTS FROM THE COHORT TO INCLUDE 24 HOUR DIETARY RECALLS, FOOD SECURITY, DQSQ, FUNCTIONAL LIMITATIONS, AND QUALITY OF LIFE MEASURES. 2A: EXTEND CRITERION VALIDITY TESTING OF THE DQSQ IN A SAMPLE OF VERY ADVANCED AGE BY CONTRASTING THE ASSOCIATIONS OF DIETARY PATTERNS, HEI, AND DQSQ, WITH THE HEALTH AND LIFE QUALITY OUTCOMES OF INTEREST WITH THOSE FROM THE ORIGINAL DATASET OF THE YOUNGER SAMPLE THAT WAS EVALUATED IN 2004 WITH THE SAME COMPREHENSIVE ASSESSMENT AND THAT WAS USED TO ORIGINALLY DEVELOP AND VALIDATE THE DQSQ.

TIPPING THE SCALE MENTORING PROGRAM

TELEMEDICINE GRANT

CAN WE AVOID ANTICOAGULATION IN EXTRACORPOREAL LIFE SUPPORT (ECLS)? THE IMPACT OF ANTICOAGULATION MONITORING AND ADMINISTRATION PRACTICES

HEALTH CARE AND OTHER FACILITIES

NSL - BACCALAUREATE NURSING - LOAN GRANT WITH FUNDS FOR NEW BUDGET PERIOD

ARRA - EQUIPMENT TO ENHANCE TRAINING FOR HEALTH PROFESSIONALS: NEPR

CONGRESSIONALLY-MANDATED HEALTH INFORMATION TECHNOLOGY GRANTS

HEALTH CARE AND OTHER FACILITIES

GERIATRIC CONDITIONS AND TREATMENT BURDEN IN OLDER ADULTS WITH NON-MUSCLE-INVASIVE BLADDER CANCER AND THEIR CAREGIVERS

AFFORDABLE CARE ACT (ACA) GRANTS FOR SCHOOL-BASED HEALTH CENTERS CAPITAL PROGRAM

COLLABORATIVE RESEARCH: E-CORE RII: SUSTAINABLE PROGRAMS ADVANCING RESEARCH AND KNOWLEDGE ACROSS NORTH DAKOTA -THIS PROJECT LED BY NORTH DAKOTA STATE UNIVERSITY WILL BUILD A STRONG AND SUSTAINABLE STEM COMMUNITY ACROSS NORTH DAKOTA. COLLABORATING INSTITUTIONS INCLUDE CANKDESKA CIKANA COMMUNITY COLLEGE, MAYVILLE STATE UNIVERSITY, MINOT STATE UNIVERSITY, NUETA HIDATSA SAHNISH COLLEGE, SITTING BULL COLLEGE, TURTLE MOUNTAIN COLLEGE, UNITED TRIBES TECHNICAL COLLEGE, UNIVERSITY OF NORTH DAKOTA, AND VALLEY CITY STATE UNIVERSITY. THE PROJECT WILL FOCUS ON CONNECTING RESEARCHERS ACROSS NORTH DAKOTA, IMPROVING STEM OPPORTUNITIES IN RURAL AREAS, AND FACILITATING STEM EDUCATION FOR STUDENTS AT TRIBAL COLLEGES. IT WILL ADDRESS THE LACK OF STEM OPPORTUNITIES IN RURAL COMMUNITIES, CHALLENGES FACED BY STUDENTS AT TRIBAL COLLEGES, COMMUNITY COLLEGES, AND PRIMARILY UNDERGRADUATE INSTITUTIONS, AS WELL AS THE BARRIERS POSED BY DISTANCE BETWEEN RESEARCH INSTITUTIONS. BY CREATING NEW PARTNERSHIPS BETWEEN SCHOOLS, COLLEGES, AND UNIVERSITIES, THE PROJECT WILL INCREASE OPPORTUNITIES FOR STEM EDUCATION AND CAREERS. IT WILL PROMOTE HANDS-ON LEARNING, SOCIAL CONNECTIONS IN STEM EDUCATION, AND OPPORTUNITIES FOR STUDENTS FROM ACROSS THE STATE TO SUCCEED. IT WILL ALSO BRING RESEARCHERS TOGETHER TO SOLVE IMPORTANT PROBLEMS. THE PROJECT WILL MEASURE ITS SUCCESS THROUGH DETAILED EVALUATIONS AND AIMS TO LEAVE A LASTING IMPACT BY CREATING NEW EDUCATIONAL PATHWAYS, STRONGER RESEARCH NETWORKS, AND A MORE SKILLED STEM WORKFORCE IN NORTH DAKOTA. THIS PROJECT WILL ESTABLISH A COMPREHENSIVE AND SUSTAINABLE STEM ECOSYSTEM IN NORTH DAKOTA THROUGH THREE TARGETED FOCUS AREAS: ADMINISTRATIVE CORE, STEM PATHWAYS CORE, AND TRIBAL COLLEGES & UNIVERSITIES CORE. THE PROJECT TEAM WILL CONNECT GEOGRAPHICALLY DISPERSED RESEARCHERS, ENHANCE STEM LITERACY AMONG RURAL COMMUNITIES, AND STRENGTHEN STEM PARTICIPATION AT TRIBAL COLLEGES. THE TEAM WILL USE TARGETED STRATEGIES TO MITIGATE BARRIERS, SUCH AS LIMITED RURAL OPPORTUNITIES AND GEOGRAPHICAL ISOLATION. THROUGH INTERDISCIPLINARY RESEARCH NETWORKS, EXPANDED STEM OUTREACH, AND RELEVANT EDUCATIONAL PROGRAMMING AND RESEARCH, THE PROJECT TEAM WILL FOSTER COLLABORATION ACROSS NORTH DAKOTA INSTITUTIONS, BROADEN PARTICIPATION IN STEM, AND ENHANCE EDUCATIONAL AND WORKFORCE OUTCOMES. PARTNERSHIPS BETWEEN UNIVERSITIES, TRIBAL COLLEGES, AND RURAL SCHOOLS WILL ENSURE ENDURING IMPACTS, INCLUDING HEIGHTENED RESEARCH CAPACITY AND A STRONGER STEM WORKFORCE. KEY METRICS, LONGITUDINAL EVALUATION, AND SUSTAINABILITY PLANS WILL GUIDE THE PROJECT'S PROGRESS, AIMING TO CREATE A THRIVING STEM LANDSCAPE THAT ALIGNS WITH NORTH DAKOTA?S STRATEGIC GOALS. THIS PROJECT IS SUPPORTED BY THE RESEARCH INFRASTRUCTURE IMPROVEMENT (RII) PROGRAM: EPSCOR COLLABORATIONS FOR OPTIMIZING RESEARCH ECOSYSTEMS (E-CORE). E-CORE SUPPORTS JURISDICTIONS IN BUILDING RESEARCH CAPACITY AND RESEARCH INFRASTRUCTURE TO DRIVE SUBSTANTIVE AND SUSTAINABLE IMPACTS TO THEIR RESEARCH ECOSYSTEMS. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

HEALTH CARE AND OTHER FACILITIES

HEALTH CARE AND OTHER FACILITIES

HEALTH CARE AND OTHER FACILITIES

OBESITY AND DIETARY ASSESSMENT IN AGING RURAL POPULATIONS

SPECIAL PROJECTS OF NATIONAL SIGNIFICANCE

GEISINGER RURAL AGING STUDY (GRAS)

GEISINGER RURAL AGING STUDY (GRAS)

GEISINGER RURAL AGING STUDY (GRAS)

GEISINGER RURAL AGING STUDY (GRAS)

RURAL AGING STUDY (GEISINGER)

RURAL AGING STUDY (GEISINGER)

RURAL AGING STUDY (GEISINGER)

NOVEL TOOLS FOR DETECTING FGF8 FOR DEVELOPMENTAL BIOLOGY RESEARCH

GNG5 FUNCTION IN NEURAL PROGENITORS

HEALTH CARE AND OTHER FACILITIES

GEISINGER RURAL AGING STUDY (GRAS)

MINORITY SERVING INSTITUTIONS PARTNERSHIP IMPLEMENTATION GRANTS

PROJECT FIND SAFE II WILL SUPPORT HEALTH CARE AGENCIES, LAW ENFORCEMENT, PUBLIC SAFETY AGENCIES, NONPROFIT ORGANIZATIONS, AND TRIBAL COMMUNITIES TO DEVELOP PROGRAMS DESIGNED TO PREVENT AND RESPOND EFFECTIVELY TO THE WANDERING OF INDIVIDUALS SUCH AS THOSE WITH DEMENTIA, ALZHEIMERS, OR CHILDREN WITH DEVELOPMENTAL DISABILITIES. THESE APPROACHES INCLUDE: PREVENTION AND RESPONSE TRAINING; DEVELOPMENT OF EMERGENCY PROTOCOLS FOR SCHOOL OFFICIALS AND FIRST RESPONDERS; EFFORTS TO ENSURE THE SAFETY OF VULNERABLE INDIVIDUALS; AND THE IMPLEMENTATION AND OPERATION OF NOTIFICATION SYSTEMS TO ASSIST IN THE RECOVERY OF MISSING INDIVIDUALS.

ADDRESSING DIVERSITY, EQUITY, AND INCLUSION SMP STATE PROGRAMS

TELEMEDICINE GRANT

KEYHIE_STAR

6 MONTH NO COST EXTENSION

RYAN WHITE HIV/AIDS PROGRAM PART C EIS COVID-19 RESPONSE

NORTH DAKOTA PUBLIC HEALTH WORKFORCE ECHO TRAINING

THE PRIMARY GOAL OF THIS PROJECT IS TO COMPLETE THE DEVELOPMENT OF GENOMIC-BASED TECHNOLOGY TO INCREASE THE SPEED AND EFFICIENCY OF SELECTING WHITE PINE BLISTER RUST (WPBR) RESISTANT AND CLIMATE ADAPTED WHITEBARK PINE SEED SOURCES THAT CAN BE USED TO CONSERVE AND RESTORE POPULATIONS THROUGHOUT ITS NATURAL RANGE IN THE US AND CANADA. THE MODERN GENOMIC TECHNOLOGY IS NOT MEANT TO TOTALLY REPLACE CONVENTIONAL PHENOTYPE-BASED APPROACHES, BUT RATHER TO SIGNIFICANTLY INCREASE, BY SEVERAL ORDERS OF MAGNITUDE, THE AMOUNT OF MATERIAL THAT CAN BE SCREENED PER UNIT TIME AND COST. THERE IS AN URGENT NEED TO HAVE A LARGE SUPPLY OF GENETICALLY DIVERSE, WHITE PINE BLISTER RUST RESISTANT AND CLIMATE ADAPTED SEED SOURCES FOR RESTORATION, YET THE CONVENTIONAL APPROACHES SIMPLY CANNOT IDENTIFY THESE SOURCES IN THE CRITICALLY SHORT TIME FRAME WHEN THEY ARE NEEDED. AN INDIRECT CONSEQUENCE OF THIS LIMITED NUMBER OF APPROPRIATE SEED SOURCES IS THAT RESTORATION PLANTATIONS MIGHT BE ESTABLISHED WITH TOO LITTLE GENETIC DIVERSITY LEADING TO LOSS OF FUTURE ADAPTIVE DIVERSITY AND POPULATION INBREEDING.DEVELOPMENT OF APPLIED GENOMIC TECHNOLOGY PROCEEDS IN THREE PHASES:PHASE 1, SEQUENCE THE WHITEBARK PINE GENOME.PHASE 2, CONDUCT GENOME WIDE ASSOCIATION STUDIES (GWAS) AND GENOTYPE BY ENVIRONMENT STUDIES (GEA) TO IDENTIFY GENETIC MARKERS THAT CAN BE USED IN HIGH-THROUGHPUT SCREENINGPHASE 3, TRAIN FOREST RESOURCE SCIENTISTS AND MANAGERS IN THE USE OF THIS TECHNOLOGY.PHASE 1 WAS INITIATED IN 2020 AND WILL BE COMPLETED IN 2023. THIS APPLICATION REQUESTS FUNDING FOR PHASE 2 AND PHASE 3 WHICH WILL BEGIN IN LATE 2023 AND BE COMPLETED BY LATE 2025

SPECIAL PROJECTS OF NATIONAL SIGNIFICANCE

HEALTH CARE AND OTHER FACILITIES

CONGRESSIONALLY-MANDATED HEALTH INFORMATION TECHNOLOGY GRANTS

THIS ACTION APPROVES AN AWARD IN THE AMOUNT OF $50,000 TO THE MISSION HEALTHCARE FOUNDATION TO FUND 11 WORKSHOPS TO EDUCATE ASTHMATICS, PARENTS, SCHO

CONGRESSIONALLY-MANDATED HEALTH INFORMATION TECHNOLOGY GRANTS

RURAL HEALTH OUTREACH SPECIAL INITIATIVE

RYAN WHITE TITLE III HIV CAPACITY DEVELOPMENT AND PLANNING GRANTS

RURAL HEALTH NETWORK DEVELOPMENT PLANNING GRANT PROGRAM

ND INCREASING COVID 19 VACCINES

AORTIC WALL DISTENSIBILITY IN THE GROWTH AND RUPTURE OF ABDOMINAL AORTIC ANEURYSM

HMORN CONFERENCE ON CLINICAL EFFECTIVENESS

THE KING COUNTY LIBRARY SYSTEM IN ISSAQUAH, WASHINGTON, WILL EXPAND INTERNET ACCESS FOR POPULATIONS FOR WHOM BROADBAND AVAILABILITY IS LIMITED AND CONNECTIVITY FEES ARE COST PROHIBITIVE. THE INITIATIVE WILL FOCUS ON FOUR HIGH-NEED COMMUNITIES ACROSS KING COUNTY, NAMELY SENIORS; K-12 STUDENTS; PEOPLE EXPERIENCING HOMELESSNESS; AND ASSET LIMITED, INCOME CONSTRAINED, EMPLOYED (ALICE) HOUSEHOLDS. THE LIBRARY WILL PURCHASE 134 HOTSPOTS AND WILL COVER MONTHLY COSTS OF CONNECTION SERVICES. THE PROJECT WILL HELP CLOSE THE DIGITAL DIVIDE IN THESE COMMUNITIES BY USING MOBILE TECHNOLOGIES TO PROVIDE ACCESS BEYOND THE WALLS OF LIBRARY BUILDINGS. LOANING INTERNET-CONNECTED HARDWARE TO POPULATIONS MOST AFFECTED BY THE PANDEMIC WILL ENABLE THEM TO ACCESS VITAL RESOURCES AND CONNECT TO PATHWAYS THAT CAN HELP DRIVE RECOVERY.

RYAN WHITE HIV/AIDS PROGRAM PART D WICY COVID-19 RESPONSE

NSL - BACCALAUREATE NURSING - LOAN GRANT WITH FUNDS FOR NEW BUDGET PERIOD

THIS ACTION APPROVES AN AWARD IN THE AMOUNT OF $20,000 TO THE MISSION HEALTH SYSTEM FOUNDATION TO ASSIST IN THE REDUCTION OF ASTHMA TRIGGERS BY PROVIDING EVIDENCE -BASED PRACTICES AND TRAINING FOR ASTHMA DIAGNOSIS TREATMENT AND MANAGEMENT. TRAINING WILL BE DELIVERED DURING ASTHMA HOME VISITS AND PATIENTS WILL BE GIVEN RESOURCES TO REDUCE ASTHMA TRIGGERS IN THE HOME.

DENNY CREEK RIPARIAN/WETLAND RESTORATION

LOAN GRANT WITH FUNDS FOR NEW BUDGET PERIOD

FROM LAB TO LABOR: ADVANCING DIABETES PREGNANCY CARE - ABSTRACT THE GLOBAL RISE IN OBESITY AND TYPE 2 DIABETES HAS LED TO AN INCREASE IN PREGESTATIONAL DIABETES, SIGNIFICANTLY RAISING RISKS DURING PREGNANCY. UNCONTROLLED HYPERGLYCEMIA IS TERATOGENIC, RESULTING IN ADVERSE MATERNAL AND FETAL OUTCOMES, WITH DIABESITY BEING A CRITICAL AREA OF FOCUS FOR THE DIABETES IN PREGNANCY STUDY GROUP OF NORTH AMERICA (DPSG-NA). SINCE ITS INCEPTION IN 1997, DPSG-NA HAS AIMED TO IMPROVE PREGNANCY OUTCOMES IN DIABETES BY ADVANCING RESEARCH, SHAPING MEDICAL POLICIES, AND INFLUENCING PROFESSIONAL PRACTICES. THE BIENNIAL DPSG-NA MEETINGS HAVE DRIVEN RESEARCH PROGRESS, ADDRESSING CONTROVERSIES IN GDM SCREENING, DIAGNOSIS, AND TREATMENT, AND HAVE EVOLVED TO INCLUDE DISCUSSIONS ON CONGENITAL MALFORMATIONS, PERINATAL MORTALITY, AND COST-EFFECTIVE DIABETES MANAGEMENT. THE 18TH BIENNIAL MEETING IN 2025, TITLED FROM LAB TO LABOR: ADVANCING DIABETES PREGNANCY CARE, WILL EMPHASIZE NUTRITION IN PREGNANCY AND AIM TO SUPPORT EARLY- STAGE INVESTIGATORS (ESIS) IN THE FIELD. KEY OBJECTIVES OF THE MEETING INCLUDE: 1) SUPPORTING ESIS THROUGH PLANNING AND NETWORKING OPPORTUNITIES, EXPOSING ESIS TO GROUNDBREAKING WORK, FOSTERING NEW PROJECTS AND ADDRESSING KNOWLEDGE GAPS IN DIABETES AND PREGNANCY RESEARCH, 2) PRESENTING OF THE LATEST RESEARCH IN DIABETES AND NUTRITION IN PREGNANCY BY WELL-ESTABLISHED INVESTIGATORS, FACILITATING KNOWLEDGE EXCHANGE AND FOSTERING COLLABORATION AMONG EARLY-CAREER AND EXPERIENCED INVESTIGATORS, AND 3) DISSEMINATING FINDINGS, ESPECIALLY TO PRACTITIONERS TREATING UNDERSERVED POPULATIONS, ENSURING A COMPREHENSIVE UNDERSTANDING OF CHALLENGES AND SOLUTIONS IN MANAGING DIABETES IN DIVERSE POPULATIONS. EFFORTS TO ENCOURAGE PARTICIPATION FROM UNDERSERVED REGIONS WILL ENHANCE THE SCOPE OF DISCUSSIONS, WHILE COLLABORATIVE RESEARCH PRESENTATIONS AND ABSTRACT SUBMISSIONS WILL STIMULATE FURTHER ADVANCEMENTS IN THE FIELD. THE MEETING'S OUTCOMES WILL BE SHARED THROUGH PEER-REVIEWED PUBLICATIONS, CONTRIBUTING TO A ROBUST RESEARCH COMMUNITY FOCUSED ON IMPROVING OUTCOMES FOR PREGNANCIES COMPLICATED BY DIABETES.

DEFINING RESEARCH AND CARE IN DIABETES IN PREGNANCY - PROJECT SUMMARY THE 17TH BIENNIAL MEETING OF THE DIABETES IN PREGNANCY STUDY GROUP OF NORTH AMERICA (DPSG-NA) WILL BE HELD ON OCTOBER 26-28, 2023 AS A HYBRID VIRTUAL AND IN-PERSON MEETING AT THE PHYSICIANS CONFERENCE CENTER AT INOVA FAIRFAX MEDICAL CAMPUS IN FALLS CHURCH, VA. THIS 3-DAY RESEARCH MEETING FOCUSES ON PREGNANT INDIVIDUALS LIVING WITH TYPE 1, TYPE 2, AND GESTATIONAL DIABETES MELLITUS. SINCE ITS INCEPTION OVER 25 YEARS AGO, THE DPSG-NA MEETINGS HAVE BEEN A VEHICLE FOR THE DISSEMINATION OF DATA, GATHERED THROUGH COLLABORATION AMONG BASIC, TRANSLATIONAL, CLINICAL, AND PUBLIC HEALTH RESEARCHERS AND PRACTITIONERS BOTH IN THE UNITED STATES AND ABROAD. THE MEETING COVERS A BROAD RANGE OF ISSUES RELATED TO DIABETES IN PREGNANCY. THE FOCUS OF THE MEETING IS TO HIGHLIGHT MAJOR, TIMELY RESEARCH AREAS TO CATALYZE FUTURE DISCOVERY. THE MAJOR GOAL OF THIS MEETING IS, AND HAS HISTORICALLY BEEN, TO SERVE AS A DRIVING FORCE FOR DISCUSSIONS AND NEW COLLABORATIONS THAT OPEN NOVEL AREAS OF EXPLORATION INTO PREVENTION, TREATMENT, AND MANAGEMENT APPROACHES. THESE EFFORTS ARE EXPECTED TO REDUCE THE BURDEN OF DIABETES DISEASE AND ITS CONSEQUENCES FOR PREGNANT INDIVIDUALS AND THEIR OFFSPRING. THE 17H BIENNIAL MEETING HAS A STRONG EMPHASIS ON DIVERSITY, EMPHASIZING THE IMPORTANCE OF SOCIAL DETERMINANTS OF HEALTH AND GLOBAL PERSPECTIVES, INCLUDING LOW-AND-MIDDLE-INCOME COUNTRIES. THE MEETING GOALS WILL BE ACHIEVED THROUGH ORAL PRESENTATIONS, ROUNDTABLE DISCUSSIONS, AND DEBATES THAT WILL BRING TOGETHER THE WORLD’S EXPERTS, YOUNG INVESTIGATORS, STUDENTS, AND TRAINEES WHO HAVE A COMMITTED INTEREST TO DIABETES IN PREGNANCY. THE PROGRAM INCLUDES 4 KEYNOTE ADDRESSES THAT EACH WILL BE DEDICATED TO A GIANT IN THE FIELD OF DIABETES IN PREGNANCY. THE FIRST KEYNOTE WILL BE GIVEN IN MEMORY OF ODED LANGER BY ROBERTO ROMERO, MD, DMED, SCI. DR. ROMERO WILL SPEAK ON THE PREDICTION AND PREVENTION OF OBSTETRICAL DISEASES. IN ADDITION, CYNTHIA GYAMFI-BANNERMAN, MD, MS WILL GIVE THE ELIZABETH THOM MEMORIAL LECTURE WHERE DR. GYAMFI-BANNERMAN WILL SPEAK OF DR. THOM’S CONTRIBUTION AS THE BIOSTATISTICIAN OF THE MFMU NETWORK IN CHANGING CLINICAL CARE IN DIABETES. FINALLY, KEVAN HEROLD, MD WILL SPEAK IN THE LOIS JOVANOVIC MEMORIAL LECTURE AND WILL ADDRESS STRATEGIES TO REDUCE THE DIABETES EPIDEMIC IN THE UNITED STATES. OTHER SPEAKERS INCLUDE ESTABLISHED EXPERTS AND YOUNG INVESTIGATORS, WITH ABOUT 20% OF THE MEETING TIME ALLOCATED FOR SPEAKER-CONFEREE DISCUSSIONS. YOUNG INVESTIGATOR PRESENTATIONS ARE AN IMPORTANT ASPECT OF THE MEETING, AND THEY ARE AN EFFECTIVE TOOL TO HELP BRING A NEW GENERATION OF SCIENTISTS INTO OUR COMMUNITY AND FOSTER THEIR MATURATION. INFORMAL DISCUSSIONS AMONG CONFEREES ARE HIGHLIGHTS OF THIS UNIQUE MEETING THAT FOSTERS A COLLABORATIVE, MULTIFACETED APPROACH TO IMPROVING THE HEALTH AND WELLBEING OF PREGNANT WOMEN WITH DIABETES AND THEIR OFFSPRING.

RURAL HEALTH CLINIC VACCINE CONFIDENCE PROGRAM

COPPERFIELD DRAW

ORHP SPECIAL PROJECTS

UNIVERSAL NEWBORN HEARING AND SCREENING

TRAINING IN PRIMARY CARE MEDICINE-INTERDISCIPLINARY AND INTERPROFESSIONAL GRADUATE JOINT DEGREE PROG

DEVELOPMENT OF RURAL PACE IN NORTHCENTRAL PENNSYLVANIA