Croma Inc

LONG STROKE WAVEFRONT CORRECTORS FOR RETINAL IMAGING

2023 HPF HER - ARLINGTON STREET CHURCH

2017 HPF SAT - FOUNDATION FOR THE PRESERVATION OF 20 ARLINGTON STREET

SBIR PHASE I: MEDMICROMAPS A NOVEL E-LEARNING PLATFORM AND IMMERSIVE EXPERIENCE IN THE MICROBIAL METAVERSE FOR LIFE SCIENCE LEARNERS -THE BROADER/COMMERCIAL IMPACT OF THIS SBIR PHASE I PROJECT IS TO ADVANCE SCIENCE EDUCATION IN MICROBIOLOGY THROUGH AN INTERACTIVE, VIRTUAL MICROBE WORLD. THIS INNOVATION WILL MAKE COMPLEX SCIENTIFIC CONCEPTS MORE ACCESSIBLE TO DIVERSE LEARNERS, INCLUDING THOSE TRADITIONALLY UNDERREPRESENTED IN STEM. THE APPLICATION ALLOWS STUDENTS TO EXPLORE MICROSCOPIC ORGANISMS AT VARIOUS SCALES, ENHANCING UNDERSTANDING OF MICROBIOLOGY, IMMUNOLOGY, AND PUBLIC HEALTH. BY PROVIDING IMMERSIVE, HANDS-ON EXPERIENCES, IT BRINGS TEXTBOOK CONCEPTS TO LIFE, POTENTIALLY IMPROVING COMPREHENSION AND RETENTION. THE PROJECT TARGETS EDUCATIONAL INSTITUTIONS OFFERING LIFE SCIENCE PROGRAMS, PARTICULARLY UNDERGRADUATE MEDICAL EDUCATION, WITH PLANS TO EXPAND TO OTHER DISCIPLINES AND SECONDARY EDUCATION MARKETS. THIS TECHNOLOGY ADDRESSES THE GROWING NEED FOR ENGAGING, TECHNOLOGY-ENHANCED LEARNING TOOLS IN STEM EDUCATION. BY IMPROVING SCIENCE LITERACY ON MICROBIAL INFECTIONS, VACCINES, AND ANTIBIOTICS, THE PROJECT SERVES THE NATIONAL INTEREST IN ADVANCING HEALTH AND SCIENTIFIC UNDERSTANDING. THE BUSINESS MODEL FOCUSES ON INSTITUTIONAL LICENSING, WITH POTENTIAL FOR INDIVIDUAL SUBSCRIPTIONS. THIS APPROACH COULD SIGNIFICANTLY IMPACT HOW STUDENTS LEARN ABOUT AND INTERACT WITH THE MICROBIAL WORLD, FOSTERING A DEEPER APPRECIATION FOR LIFE SCIENCES. THIS SMALL BUSINESS INNOVATION RESEARCH (SBIR) PHASE I PROJECT ADDRESSES THE CHALLENGE OF EFFECTIVELY TEACHING COMPLEX MICROBIOLOGY CONCEPTS TO UNDERGRADUATE MEDICAL STUDENTS. THE RESEARCH OBJECTIVES FOCUS ON LEVERAGING EXTENDED REALITY (XR) TECHNOLOGY AND ARTIFICIAL INTELLIGENCE TO ENHANCE THE LEARNING EXPERIENCE OF INFECTIOUS DISEASES AND MICROBES. THE PROPOSED RESEARCH INVOLVES DEVELOPING A NOVEL XR APPLICATION USING THE META SDK PLATFORM WITHIN THE UNITY GAME ENGINE, INCORPORATING 3D MICROBIAL ASSETS CREATED WITH BLENDER AND ADOBE SOFTWARE. THESE ASSETS WILL FEATURE REALISTIC TEXTURES BASED ON MICROSCOPY IMAGES, ENSURING SCIENTIFIC ACCURACY. THE SYSTEM WILL EMPLOY A BACTERIOPHAGE AI-ASSIST TO ADAPT CONTENT DELIVERY BASED ON INDIVIDUAL LEARNING STYLES, INCLUDING AUDITORY, VISUAL, KINESTHETIC, AND TEXT-BASED APPROACHES. THE ANTICIPATED TECHNICAL RESULTS INCLUDE A CROSS-PLATFORM ACCESSIBLE WEBGL BUILD COMPATIBLE WITH XR HEADSETS, MOBILE DEVICES, AND PERSONAL COMPUTERS. THIS INNOVATIVE APPROACH AIMS TO SIGNIFICANTLY IMPROVE LEARNING OUTCOMES FOR BOTH TRADITIONAL AND NON-TRADITIONAL STUDENTS BY PROVIDING AN IMMERSIVE, INTERACTIVE, AND PERSONALIZED EDUCATIONAL EXPERIENCE. THE PROJECT'S SCOPE ENCOMPASSES THE DEVELOPMENT, TESTING, AND EVALUATION OF THIS XR-BASED LEARNING SYSTEM, WITH THE POTENTIAL TO POSITIVELY IMPACT MICROBIOLOGY EDUCATION IN UNDERGRADUATE MEDICAL CURRICULA. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

IN THE PROPOSED PROJECT BOSTON MICROMACHINES CORPORATION (BMC) PLANS TO DEMONSTRATE A NEW ARCHITECTURE AND INTEGRATION APPROACH FOR COMPACT ROBUST LARGE-FORMAT DEFORMABLE MIRRORS (LFDM) AND TO SHOW A FEASIBLE PATH FOR SCALING UP THAT DEMONSTRATION PLATFORM AND MANUFACTURING INTEGRATION APPROACH TO LARGER FORMATS WITH UP TO 10 000 ACTUATORS. THESE LFDMS WILL TAKE ADVANTAGE OF BMC S PROVEN AND SCALABLE MICROELECTROMECHANICAL (MEMS) SILICON PROCESSING TECHNOLOGY WHILE SUBSTANTIALLY REDUCING THE REQUIRED SIZE AND WEIGHT OF THE DRIVER SYSTEM AND ELIMINATING THE NEED FOR HIGH-DENSITY CABLES. NASA S EXOPLANET EXPLORATION PROGRAM (EEP) RECENTLY IDENTIFIED LFDMS AS A CRITICAL TECHNOLOGY GAP FOR THE HIGH-RESOLUTION CORONAGRAPH INSTRUMENTS THAT ARE AT THE CORE OF EEP S TECHNOLOGY PLAN. THIS PROPOSAL SPECIFICALLY ADDRESSES EEP S REQUEST FOR TECHNOLOGY DEVELOPMENT EFFORTS THAT REDESIGN THE ELECTRONIC INTERCONNECTORS TO THE ACTUATORS AND MINIATURIZE THE DRIVE ELECTRONICS THEREBY MAKING LFDM SYSTEMS MORE TECHNOLOGICALLY READY FOR SPACE MISSIONS. IN THIS PROJECT BMC WILL DEMONSTRATE FEASIBILITY OF LOW-STRESS HIGH-RELIABILITY BONDING OF MEMS ARRAYS TO INTERPOSERS. ALSO BMC WILL DEMONSTRATE COMPLETE INTEGRATION OF A MEMS SYSTEM BASED ON THE NEW LDFM DESIGN. THE INTEGRATED SYSTEM WILL FEATURE 32 32 ACTUATOR MEMS ARRAYS CAPABLE OF UP TO 1.5 M OF STROKE 1 KHZ FRAME UPDATE RATE AND 14 BIT PRECISION. IT WILL CONSUME NO MORE THAN 8 WATTS OF POWER AND WILL BE CONTAINED WITHIN A CUBIC VOLUME MEASURING 100 MM ON A SIDE. FINALLY BMC WILL DEVELOP A TECHNOLOGY PLAN AND DESIGN FOR SCALE-UP OF THE APPROACH TO LFDMS WITH UP TO 96 96 ACTUATORS.

NEW SBIR PHASE I 2009; TITLE: SERS RAMAN SENSOR BASED ON DIAMETER-MODULATED SAPPHIRE FIBER; PI: JIAN ZHANG

SBIR PHASE I: SUPERPENETRATION MULTIPHOTON MICROSCOPY WITH MEMS SLMS

LOW COST FIBER OPTIC TEMPERATURE SENSOR

THE AIM OF THE PROPOSED PROJECT IS TO DEMONSTRATE A NEW ARCHITECTURE AND INTEGRATION APPROACH FOR COMPACT ROBUST LARGE-FORMAT DEFORMABLE MIRROR (LFDM) SYSTEMS AND TO SHOW A FEASIBLE PATH FOR SCALING UP THAT DEMONSTRATION PLATFORM AND MANUFACTURING INTEGRATION APPROACH TO LARGER FORMATS WITH UP TO 10 000 ACTUATORS. THESE LFDMS WILL TAKE ADVANTAGE OF BOSTON MICROMACHINES CORPORATION'S (BMC'S) PROVEN AND SCALABLE MICROELECTROMECHANICAL (MEMS) SILICON PROCESSING TECHNOLOGY WHILE SUBSTANTIALLY REDUCING THE REQUIRED SIZE AND WEIGHT OF THE DRIVER SYSTEM AND ELIMINATING THE NEED FOR HIGH-DENSITY CABLES.