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GH19-1932 BUILDING AND IMPROVING LABORATORY CAPACITY AND QUALITY IN THE DEMOCRATIC REPUBLIC OF CONGO (DRC) UNDER THE PRESIDENT'S EMERGENCY PLAN FOR AIDS RELIEF (PEPFAR)

STRENGTHENING PUBLIC HEALTH LABORATORY SYSTEMS IN THE REPUBLIC OF CAMEROON UNDER

STRENGTHENING PUBLIC HEALTH LABORATORY SYSTEMS IN THE REPUBLIC OF CAMEROON UNDER THE PRESIDENT'S EMERGENCY PLAN FOR AIDS RELIEF (PEPFAR) - CDC-RFA-GH17-1719

STRENGTHENING PUBLIC HEALTH LABORATORY SYSTEMS IN THE REPUBLIC OF CAMEROON UNDER THE PRESIDENT'S EMERGENCY PLAN FOR AIDS RELIEF (PEPFAR) - IN THIS FUNDING REQUEST, GLOBAL HEALTH SYSTEMS SOLUTIONS (GHSS) WILL ASSIST THE GOVERNMENT OF CAMEROON TO STRENGTHEN AND EXPAND LABORATORY SYSTEMS AND SERVICES, AND BUILD THE COMPETENCIES OF LABORATORY STAFF IN ORDER TO IMPROVE THE QUALITY OF TESTING NEEDED TO SUPPORT HIV PREVENTION, TREATMENT AND CARE GOALS IN PRIORITIZED NATIONAL AND SUB-NATIONAL GEOGRAPHIC LOCATIONS OF CAMEROON THAT HAVE BEEN PRIORITIZED FOR INTERVENTION BY CDC/PEPFAR. GHSS WILL LEVERAGE ITS VAST EXPERIENCE ACQUIRED OVER THE LAST 10 YEARS, AS THE SOLE CDC/PEPFAR LABORATORY-IMPLEMENTING PARTNER, TO IMPLEMENT THE ACTIVITIES OUTLINED IN THIS APPLICATION AND ADDRESS EXISTING GAPS AND CHALLENGES THAT HINDER ACCESS TO AND AVAILABILITY OF QUALITY LABORATORY SERVICES. GHSS SPECIFIC STRATEGIES FOR THE REQUEST FOR FUNDING APPLICATION (RFA) WILL INCLUDE: 1) IMPLEMENT LABORATORY QMS GEARED TOWARDS IMPROVING THE QUALITY OF TEST RESULTS USING INNOVATIVE QUALITY STRATEGIES, LEADING TO THE ACCREDITATION OF VL/EID AND REGIONAL HOSPITAL LABORATORIES (RHLS); 2) EXTEND EQA COVERAGE AND PARTICIPATION FOR HIV, EID, VIRAL LOAD, CD4, TB AND OTHER HIV RELATED METABOLITES TO SUPPORT CQI; 3) PROVIDE TECHNICAL ASSISTANCE AND SUPPORT TRAINING/CAPACITY BUILDING AND MENTORING OF MOH LABORATORY PERSONNEL AND Q-CORPS TO SCALE UP CQI AND ENSURE INSTITUTIONALIZATION AND SUSTAINABILITY OF CQI ACTIVITIES; 4) ESTABLISH AND STRENGTHEN EXISTING SAMPLE REFERRAL AND TRANSPORT NETWORKS FOR SPECIMENS AND RESULTS FOR QUALITY HTC, PMTCT, AND ART COVERAGE; 5) PROVIDE TECHNICAL ASSISTANCE AND SUPPORT TO IMPLEMENT LIMS IN ALL VLRL AND POC FACILITIES TO FACILITATE TEST ORDERING AND REAL-TIME REPORTING AND PROVISION OF BUFFER STOCK OF REAGENTS AND CARTRIDGES TO ENSURE CONTINUOUS TESTING; AND 6) COLLABORATE WITH AND SUPPORT THE NPHL AND DPML TO REVIEW (EXISTING), DEVELOP (NEW) AND INSTITUTIONALIZE POLICIES, STRATEGIC PLANS, TOOLS, SOPS, JOB AIDS AND ACTIVITIES GEARED TOWARD THE COORDINATION OF QMS, QA, CQI AND EQA, AND TO STRE NGTHEN THE LAB NETWORK AND SAMPLE REFERRALS. AT THE END OF THE PROJECT PERIOD, GHSS EXPECTS TO ACHIEVE THE FOLLOWING OUTCOMES: AT THE END OF THE PROJECT PERIOD, GHSS EXPECTS TO ACHIEVE THE FOLLOWING OUTCOMES: 1) IMPROVED QMS IN 100 LABORATORIES ACCORDING TO THE WHO AFRO-CDC SLIPTA PROCESS, WITH 05 VL AND 05 RHLS ACCREDITED, 05 VL AND 03 RHLS ATTAINED AT LEAST 2 SLIPTA STARS, AND THE CURRENT 5 ALREADY ACCREDITED LABS MAINTAINED. 2) ALL PEPFAR-SUPPORTED FACILITIES TESTING FOR HIVRT, EID, VL, CD4, TB ENROLLED ON EQA WITH 95% SUCCESS RATES; EQA FOR OTHER HIV RELATED METABOLITES SUPPORTED FOR 23+ LABS ON ACCREDITATION; 3) 500 HIVRT TESTING SITES, 80 HIV RELATED TESTING SITES AND 1750+ TESTERS CERTIFIED, A NETWORK OF 60 Q-CORPS SUPPORTING HARD TO REACH AREAS WITH IMPROVED QUALITY OF TEST RESULTS;4) A FUNCTIONAL INTEGRATED SPECIMEN REFERRAL NETWORK IN 10 REGIONS WITH, 50% REDUCTION IN TAT ON SPECIMEN TRANSPORTATION; 5) 80% OF VLRL AND POC FACILITIES USE LIS FOR MANAGING LABORATORY DATA WITH AN 80% REDUCTION IN DELAY IN REPORTING PATIENTS TEST RESULTS AND TRANSCRIPTION ERRORS; AND 6) EXISTING POLICIES, STRATEGIC PLANS, TOOLS, SOPS AND JOB AIDS REVIEWED AND ADOPTED; NEW POLICIES AND GUIDELINES IDENTIFIED, DEVELOPED AND IMPLEMENTED. OUR OVERALL STRATEGY TO STRENGTHEN LABORATORY SYSTEMS IN CAMEROON WILL INCLUDE; BUILDING AND IMPROVING ON DIAGNOSTIC CAPACITY, LEVERAGING AND INNOVATING NATIONAL SYSTEMS, AND TRANSITIONING ACTIVITIES TO MOH FOR SUSTAINABILITY.

BUILDING AND IMPROVING INTEGRATED LABORATORY CAPACITY AND QUALITY SERVICES IN THE DEMOCRATIC REPUBLIC OF THE CONGO (DRC) UNDER THE PRESIDENT'S EMERGENCY PLAN FOR AIDS RELIEF (PEPFAR) - IN THIS FUNDING REQUEST, THE GLOBAL HEALTH SYSTEMS SOLUTIONS (GHSS) WILL ASSIST THE GOVERNMENT OF DR CONGO TO BUILD LABORATORY CAPACITY TO IMPROVE THE QUALITY OF HIV TESTING SERVICES AND TIMELY RELEASE OF RESULTS FOR HIV PREVENTION, TREATMENT AND CARE IN 54 CDC/PEPFAR HEALTH ZONES, AND QUALITY MANAGEMENT SYSTEM (QMS) IN 29 DIAGNOSTIC LABORATORIES. GHSS WILL LEVERAGE ITS VAST EXPERIENCE ACQUIRED OVER THE LAST 13 YEARS IN IMPLEMENTING THE CDC/PEPFAR GRANTS IN CAMEROON AND DR CONGO IN PARTNERSHIP AND COLLABORATION WITH MINISTRIES OF HEALTH OF BOTH COUNTRIES, TO IMPLEMENT THE ACTIVITIES OUTLINED IN THIS APPLICATION, AND ADDRESS EXISTING CHALLENGES THAT HINDER ACCESS TO, AND AVAILABILITY OF QUALITY LABORATORY SERVICES. SPECIFIC OBJECTIVES WILL INCLUDE: 1) SCALE UP OF QUALITY ASSURANCE (QA) AND QUALITY IMPROVEMENT AT HIV RT AND TB SITES; 2) SCALE UP QUALITY TESTING FOR VL, EID AND TB FOR POC AND CONVENTIONAL TESTING LABORATORIES AND ENHANCE TIMELY DELIVERY OF RESULTS; 3) IMPLEMENT QMS IN THE MOLECULAR AND REFERRAL LABORATORIES FOR ACCREDITATION AND SUSTAINED QUALITY SERVICES; 4) SUPPORT AN INTEGRATED SAMPLE TRANSPORT NETWORK FOR IMPROVED SAMPLE MANAGEMENT; 5) IMPROVE EQUIPMENT MANAGEMENT AND PHYSICAL FACILITY FOR EFFICIENT HIV TESTING AND OTHER RELATED DISEASES; 6) SUPPORT THE DEVELOPMENT OF POLICY, GUIDELINES AND CREATION OF TWG FOR IMPROVED LABORATORY PROGRAMS IMPLEMENTATION; AND 7) IMPROVE LABORATORY DETECTION OF EARLY SIGNALS FOR EMERGING PUBLIC HEALTH THREATS. WITH LIMITED COMPLIANCE OF LABORATORIES TO ISO 15189 STANDARDS, IN DR CONGO, GHSS WILL ENROL NEW LABORATORIES INTO STEPWISE LABORATORY IMPROVEMENT PROCESS TOWARDS ACCREDITATION (SLIPTA) AND ESTABLISH A NATIONAL LABORATORY NETWORK TO REINFORCE THE STRATEGY TO STRENGTHEN SERVICES AND OPTIMIZE CASE FINDING AMONG AGYW AND KEY POPULATIONS IN LINE WITH THE PEPFAR COP 22, SUPPORT THE NATIONAL AIDS CONTROL PROGRAM (PNLS), IMPLEMENT PROGRAMMATIC PRIORITIES AND STRATEGICALLY EXPAND AND STRENGTHEN PE OPLE-CENTERED ACTIVITIES TO ATTAIN EPIDEMIC CONTROL IN HAUT KATANGA AND LUALABA AND SELECTED HEALTH ZONES IN KINSHASA. AT THE END OF THE PROJECT PERIOD, GHSS WILL ACHIEVE THE FOLLOWING OUTCOMES: 1) EXPAND COVERAGE AND IMPROVE THE QUALITY OF HIV RAPID TEST RESULTS IN 2000 SITES USING THE WHO STEPWISE PROCESS FOR IMPROVING THE QUALITY OF HIV RAPID TESTING (SPI-RT) STANDARDS AND 20 POCT SITES ENGAGED IN EARLY INFANT DIAGNOSIS, VL AND TB, AND ACHIEVE CERTIFICATION OF 100 SITES AND TESTERS; 2) INCREASE THE COVERAGE FOR VL, EID BY 20% THROUGH THE PROCUREMENT AND DISTRIBUTION OF 14500 GENEXPERT CARTRIDGES, AND BY ENSURING THAT HIGH/CRITICAL VL RESULTS ARE COMMUNICATED IN REAL TIME TO CLIENTS OR CLINICS FOLLOWING DIAGNOSIS LEADING TO AN IMPROVED PERSON-CENTERED CARE FOR EPIDEMIC CONTROL; 3) IMPROVE QMS IN 20 LABORATORIES ACCORDING TO THE WHO/AFRO/CDC SLIPTA AND ACHIEVE ACCREDITATION TO ISO 15189 IN AT LEAST FIVE LABORATORIES, RESULTING IN IMPROVED ACCURACY AND RELIABILITY OF PATIENT TEST RESULTS; 4) ESTABLISH AN INTEGRATED SAMPLE TRANSPORT NETWORK THAT WILL SUPPORT THE REDUCTION OF TURNAROUND TIME FROM SAMPLE COLLECTION TO THE USE OF RESULTS BY CLINICIANS IN PEPFAR SUPPORTED SITES FOR IMPROVED PATIENT MANAGEMENT; 5) IMPROVE EQUIPMENT MANAGEMENT AND SUPPORT UPGRADES OF LABORATORY PHYSICAL FACILITY TO IMPROVE ACCURACY, RELIABILITY OF TEST RESULTS AND FACILITATE WORK FLOW FOR A SAFE WORKING ENVIRONMENT 6) SUPPORT THE CREATION OF A LABORATORY TWG AND FACILITATE POLICY DEVELOPMENT FOR IMPROVED COORDINATION OF PARTNERS’ EFFORTS AND CREATE AN ENABLING ENVIRONMENT TO IMPROVE ADHERENCE TO QUALITY STANDARDS; 7) DECREASE RESPONSE TIME TO PUBLIC HEALTH EMERGENCIES ALLOWING STAKEHOLDERS TO ANTICIPATE ANY OUTBREAK AND PREPARE ADEQUATELY FOR RESPONSE.

STRENGTHENING NATIONAL LABORTORY SYSTEMS TOWARDS WHO-AFRO STEPWISE ACCREDITATION

DETERMINATION OF HIV DRUG RESISTANCE AMONG CHILDREN AND MOTHERS ENROLLED IN PROGR

ASSISTANCE TO FIREFIGHTERS GRANT

PS10-1052, CAMEROON: STRENGTHENING PUBLIC HEALTH LABORATORY SYSTEMS