The Aurum Institute Npc

PROGRAMMATIC IMPLEMENTATION AND TECHNICAL ASSISTANCE (TA) FOR HIV/AIDS AN

MAKWANDE ? GROWING SUSTAINABLE HIV/TB EPIDEMIC CONTROL IN SA - MAKWANDE - GROWING SUSTAINABLE HIV/TB EPIDEMIC CONTROL IN SA

SUSTAINABLE HEALTH SYSTEMS STRENGTHENING THROUGH FACILITY-BASED TECHNICAL SUPPORT

STRENGTHENING WORKPLACE INTERVENTIONS IN SMME'S IN SOUTH AFRICA

STAFFING OF KEY DISTRICTS IN SOUTH AFRICA - A PARTNERSHIP BETWEEEN THE AURUM INST

DCS ADMINISTRATIIVE REGIONS SOUTH AFRICA: GAUTENG, KWAZULA

SILAPHA: RESPECTFUL, RELIABLE AND RESPONSIVE SERVICES FOR KEY POPULATIONS BY KEY POPULATIONS

INTER-AGENCY PEPFAR ANNUAL PROGRAM STATEMENT US GOV'T MISSION TO SA

ACCELERATE TB ELIMINATION AND PROGRAM RESILIENCE ACTIVITY-HIGH BURDEN AREAS (ACCELERATE 1)

GH13-1336, S. AFRICA: DCS ADMINISTRATIIVE REGIONS SOUTH AFRICA: GAUTENG, KWAZULA

AURUM CLINICAL TRIALS UNIT - PROJECT SUMMARY SOUTHERN AND EAST AFRICA IS HOME TO 54% OF THE WORLD’S PEOPLE LIVING WITH HIV, WITH SOUTHERN AFRICA REMAINING AS THE EPICENTER OF THE GLOBAL HIV PANDEMIC. THE PROPOSED AURUM SOUTH AND EAST AFRICAN CLINICAL TRIALS UNIT (ASEA CTU) BRINGS TOGETHER A UNIQUE SOUTH–SOUTH PARTNERSHIP LED BY THREE INTERNATIONALLY RECOGNIZED INVESTIGATORS AND INCLUDING FIVE CLINICAL RESEARCH SITES (CRSS) (THREE IN SOUTH AFRICA, ONE IN ZAMBIA, AND ONE IN UGANDA) EXPERIENCED IN CONDUCTING HIV AND TB TREATMENT AND PREVENTION TRIALS. THE ASEA CTU HAS A STRONG CENTRALIZED MANAGEMENT STRUCTURE, WELL-DEVELOPED CRSS, ACCESS TO THE REQUIRED STUDY POPULATIONS, AND EXPERIENCE CONDUCTING HIV AND TB TREATMENT AND PREVENTION TRIALS. WHILE THERE HAVE BEEN ADVANCES IN TREATING AND PREVENTING HIV AND TB, WE NEED TO DEVELOP NEW TREATMENT AND PREVENTION TOOLS TO CONTROL HIV AND END THE TB EPIDEMIC. THE ASEA CTU’S PRIMARY GOAL IS TO USE ITS COLLECTIVE SCIENTIFIC LEADERSHIP, INFRASTRUCTURE, EXPERIENCE, AND STRONG COMMUNITY RELATIONSHIPS TO PARTNER WITH THREE NETWORKS TO MEET THE FOLLOWING AIMS: AIM 1: CONDUCT TRIALS OF HIV VACCINES AND ANTIBODIES FOR HIV PREVENTION. WE NEED A SAFE, EFFECTIVE HIV VACCINE THAT CAN BE DELIVERED AT SCALE TO COMBAT HIV; ANTIBODIES THAT COULD BE DELIVERED THROUGH PASSIVE INFUSION OR INDUCED BY VACCINATION WOULD COMPLEMENT TAKING ANTIRETROVIRAL THERAPY (ART) BEFORE POSSIBLE HIV EXPOSURE TO PREVENT BECOMING INFECTED WITH HIV. AIM 2: CONDUCT TRIALS OF HIV AND TB THERAPEUTICS, AND TB PREVENTIVE THERAPY AND VACCINES. IN ORDER TO END THE TB EPIDEMIC, WE NEED SHORTER, MORE POTENT COMBINATIONS OF DRUGS TO TREAT TB DISEASE OR INFECTION THAT IS SUSCEPTIBLE OR RESISTANT TO THE CURRENTLY AVAILABLE TB DRUGS, AND EFFECTIVE VACCINES TO PREVENT DISEASE OR RE-OCCURRENCE OF TB ONCE TREATED. DESPITE GREAT ADVANCES IN THE TREATMENT OF HIV, ADHERENCE TO AND RETENTION IN CARE REMAIN PROBLEMS; WE NEED NEW, SAFE, SIMPLE, EFFECTIVE, AND LONG-LASTING FORMS OF ART THAT WILL PROMOTE UPTAKE AND ADDRESS ADHERENCE CHALLENGES. AIM 3: PARTICIPATE IN STUDIES OF NOVEL LONG ACTING ANTIRETROVIRALS, MULTIPURPOSE TECHNOLOGIES, AND INTEGRATED STRATEGIES FOR HIV PREVENTION. OUR EXPERIENCE SUGGESTS THAT MORE TARGETED AND INDIVIDUALLY TAILORED INTERVENTIONS ARE REQUIRED TO OVERCOME ADHERENCE CHALLENGES WITH EXISTING PREVENTION OPTIONS. RATES OF SEXUALLY TRANSMITTED INFECTIONS (STIS) AND UNPLANNED PREGNANCY REMAIN HIGH AND UNDERSCORES THE NEED FOR TECHNOLOGIES THAT CAN PREVENT HIV AND OTHER CONDITIONS AT THE SAME TIME, SUCH AS STIS AND PREGNANCY.

APP - AAD 936-3090

GH11-1110, S. AFRICA: STAFFING OF KEY DISTRICTS IN SOUTH AFRICA - A PARTNERSHIP BETWEEEN THE AURUM INST

AN IMPLEMENTATION SCIENCE STUDY INVESTIGATING PROFILES OF MEN INTERESTED IN MEDICAL MALE CIRCUMCISION (MMC), BARRIERS AND METHODS TO INCREASE THE UPT

CONTINUITY OF TB AND HIV TREATMENT AMONG INMATES AFTER RELEASE FROM PRISON IN SOU

FEASIBILITY AND ACCEPTABILITY OF A MHEALTH-INTERVENTION TO FIND AND LINK TB CASES TO CARE

MOLEMOLEMO: BUILDING RESEARCH ADMINISTRATION EXCELLENCE IN SOUTH AFRICA - PROJECT SUMMARY THE GROWTH OF RESEARCH ACTIVITIES AT THE AURUM INSTITUTE (AURUM) IN JOHANNESBURG, SOUTH AFRICA, AND ITS OBJECTIVE TO ENGAGE IN MORE PRIMARY RESEARCH AWARDS ON THE AFRICAN CONTINENT, HAVE HIGHLIGHTED THE DESIRE FOR IMPROVED ADMINISTRATIVE OVERSIGHT OF NIH/NIAID GRANT AWARDS AND COMPLIANCE WITH NIH FUNDING POLICIES. TO ACHIEVE THE AIMS OUTLINED IN THIS APPLICATION, WE WILL WORK TOGETHER WITH VANDERBILT UNIVERSITY MEDICAL CENTER (VUMC) TO RECEIVE ADVANCED GRANTS ADMINISTRATION TRAINING AND EXPOSURE TO BEST BUSINESS PRACTICES. VUMC WILL ASSIST IN PERFORMING A MIXED METHODS NEEDS ASSESSMENT OF THE RESEARCH ADMINISTRATION AND MANAGEMENT ENVIRONMENT AT AURUM AND GENERATE AN ACTION PLAN THAT WILL IDENTIFY TRAINING NEEDS, PRIORITIZE PROCESSES, AND GUIDE PROGRAM IMPLEMENTATION. VUMC WILL LEAD VIRTUAL TRAINING WORKSHOPS ON A VARIETY OF ADMINISTRATIVE TOPICS AND WILL HOST A GRANTS MANAGEMENT PRACTICUM TO BE ATTENDED BY THE TWO PIS. A MAJOR FOCUS AND OUTPUT OF THE COLLABORATION WITH VUMC IS THE IN-HOUSE DEVELOPMENT OF A STRUCTURED GRANTS MANAGEMENT TRAINING COURSE FOR NON-US-BASED ORGANIZATIONS, TO BE COMPRISED OF ESSENTIAL AND ELECTIVE MODULES. THIS WILL BE THE VEHICLE THROUGH WHICH WE WILL ENSURE LASTING IMPACT OF THE TRAINING SUPPORT OFFERED THROUGH THIS GRANT. WITH TECHNICAL ASSISTANCE AND COURSE MATERIALS FROM VANDERBILT, THIS PROGRAM WILL BE DEVELOPED TO ENHANCE AND IMPROVE TRAINING IN GRANTS MANAGEMENT AND RESEARCH ADMINISTRATION. IN THE SECOND YEAR OF THE PRACTICUM AT VANDERBILT, AURUM ADMINISTRATORS WILL CREATE VIDEO TRAINING MODULES, WHICH WILL BE INSTRUMENTAL IN ROLLING OUT A STANDARDIZED GRANTS MANAGEMENT TRAINING PROGRAM ACROSS THE DIFFERENT AURUM ENTITIES IN SOUTH AFRICA AND ELSEWHERE IN AFRICA. IN ADDITION TO RECORDED MODULES, THE AURUM GRANTS MANAGEMENT TEAM WILL REGULARLY, AT A MINIMUM TWICE A YEAR, LEAD BOTH VIRTUAL AND IN-PERSON CLASSROOM TRAINING WORKSHOPS PER THE DEVELOPED TRAINING CURRICULUM ON A VARIETY OF ADMINISTRATIVE TOPICS RANGING FROM PROPOSAL DEVELOPMENT THROUGH AWARD CLOSEOUT. THE APPLICABLE MANDATORY MODULES WILL BECOME PART OF THE ON-BOARDING PROGRAM FOR NEW STAFF AND WE WILL CONTINUE TO DEVELOP AND UPDATE THE TRAINING COURSE AS AND WHEN NEEDED. THE PROPOSED DEVELOPMENT AWARD WILL ENABLE THE CREATION OF A HIGH-QUALITY RESEARCH ADMINISTRATION ENVIRONMENT AT THE AURUM INSTITUTE, ITS AFFILIATES, AND COLLABORATING PARTNERS, THAT IS KNOWLEDGEABLE AND COMPLIANT WITH THE FISCAL AND MANAGEMENT STANDARDS OF SPONSORED RESEARCH.

GH12-1257, S. AFRICA: SUSTAINABLE HEALTH SYSTEMS STRENGTHENING THROUGH FACILITY-BASED TECHNICAL SUPPORT

STRENGTHENING WORKPLACE INTERVENTIONS IN SMME'S IN SOUTH AFRICA