Liberty University Inc

HIGHER EDUCATION EMERGENCY RELIEF FUND DISTRIBUTION OF THE STUDENT PORTION FOR CARES ACT.

HIGHER EDUCATION EMERGENCY RELIEF FUND DISTRIBUTION OF THE INSTITUTIONAL PORTION FOR CARES ACT.

STUDIES EXAMINING QUANTITATIVE IN VIVO IMAGING OF BREAST CANCER-TARGETED, THERAPEUTIC HUMAN MAST CELLS

ANTIOXIDANT ACTIVITIES OF FREEZE DRIED ACAI BERRY (EUTERPE OLERACEA)EXTRACTS

HUMAN MAST CELLS AS A PLATFORM FOR NEW CANCER IMMUNOTHERAPY STRATEGIES - ABSTRACT THE ROLE OF HUMAN TISSUE MAST CELLS (MC) IN THE PATHOLOGY OF MANY CANCERS IS NOT KNOWN. CORRELATIVE STUDIES IN HUMANS HAVE FOUND HIGH MC NUMBERS IN THE TUMOR MICROENVIRONMENT HAVE PRO- AND ANTI-TUMOR EFFECTS AND CONTRASTING PATIENT OUTCOMES DEPENDING ON THE CANCER TYPES. WE DISCOVERED THAT HUMAN MC, ARE ACTIVATED BY, AND PROMOTE KILLING OF, CANCER CELLS IN VITRO AND IN VIVO, INFILTRATE SOLID CELL TUMOR MASSES, BIND TO TUMORS IN VIVO, CAN BE OBTAINED IN QUANTITIES NECESSARY FOR PATIENT INFUSION, CRYOPRESERVED WITHOUT LOSS OF FUNCTION, AND DISPLAY NO OVERT TOXIC EFFECTS WHEN INJECTED INTRAVENOUSLY INTO MICE WITH ENGRAFTED HUMAN TUMORS. TO DEVELOP THIS NOVEL, CELL-BASED CANCER IMMUNOTHERAPY WE WILL UTILIZE FDA APPROVED HUMANIZED IGE (WHICH BIND MC FCERI WITH EXTREMELY HIGH AFFINITY) TO TARGET MC TO CANCER CELLS. THIS NEW APPROACH IS PREMISED ON EFFICIENT, AUTOLOGOUS PRODUCTION OF MC, TUMOR TARGETING, AND EFFECTIVE TUMOR SPECIFIC KILLING. THIS STRATEGY HAS NOT BEEN FEASIBLE HERETOFORE AS THESE CELLS RESIDE IN TISSUE AND CANNOT BE OBTAINED FOR AUTOLOGOUS USE. OUR OVERALL HYPOTHESIS IS TUMOR TARGETED MC WILL BIND TO CANCER CELLS IN VITRO AND IN VIVO AFTER INTRATUMORAL OR INTRAVENOUS ADMINISTRATION AND ELICIT SIGNIFICANT ANTI-TUMOR ACTIVITY. HERE WE WILL DETERMINE THE IN VITRO AND IN VIVO ACTIVITY OF HUMAN MC AGAINST SEVERAL CANCER TYPES. THESE STUDIES COULD LEAD TO NEW ADOPTIVE CELL THERAPIES FOR DIVERSE CANCERS RANGING FROM LYMPHOMA TO BREAST CANCER.

RUI: PRECISION NANOCRYSTALLIZATION FOR ENHANCED STRENGTH AND DUCTILITY IN BULK METALS

CAREER: NEW SOLID STATE METAL FOAMS USING OXIDE REDUCTION AND INTRAPARTICLE EXPANSION

MRI: TRACK 1 ACQUISITION OF A BROAD BEAM ION MILL FOR ADVANCING RESEARCH AND TRAINING -THIS MAJOR RESEARCH INSTRUMENTATION (MRI) AWARD SUPPORTS THE ACQUISITION OF A BROAD BEAM ION MILL THAT IS USED TO PREPARE SAMPLES FOR EXAMINATION BY ELECTRON MICROSCOPY. THE DEVELOPMENT OF NEW TECHNOLOGY OFTEN REQUIRES GREATER UNDERSTANDING OF HOW MATERIALS ARE CONSTRUCTED AND CHANGE AT A VERY SMALL SCALE. TRADITIONAL SAMPLE PREPARATION BY ABRASIVE POLISHING CAN ACTUALLY OBSCURE OR DESTROY THE FEATURES THAT ARE MOST IMPORTANT. THIS INSTRUMENT WILL BE USED TO PRESERVE THOSE FEATURES AND STUDY THEM IN DETAIL. THIS BROAD BEAM ION MILL ACQUISITION WILL SUPPORT RESEARCH IN NANOSTRUCTURED ALLOY DEVELOPMENT FOR HIGH-STRENGTH, LIGHTWEIGHT STRUCTURES, LOW-COST AND EFFICIENT CATALYSTS AND ELECTRODES, AND ADVANCING ADDITIVE MANUFACTURING PROCESSES TO EXTEND THE MATERIALS CATALOG. LIBERTY UNIVERSITY PRIMARILY SERVES UNDERGRADUATE STUDENTS IN ITS SCIENCE AND ENGINEERING PROGRAMS, AND THIS INSTRUMENT AND ASSOCIATED ANALYSIS WILL BE INCORPORATED INTO ALL LEVELS OF THOSE PROGRAMS TO BETTER PREPARE FUTURE SCIENTISTS AND ENGINEERS. IN ADDITION TO BEING A CRITICAL COMPONENT OF CUTTING-EDGE RESEARCH, THE INSTRUMENT WILL ALSO BE USED IN NEW GRADUATE-LEVEL OPPORTUNITIES AT LIBERTY UNIVERSITY. AS PART OF LIBERTY UNIVERSITY?S COMMITMENT TO ENGAGE A DIVERSE RANGE OF STUDENTS IN SCIENCE, TECHNOLOGY, ENGINEERING, AND MATHEMATICS, THE INSTRUMENT WILL ALSO BE USED TO SUPPORT OUTREACH AND RECRUITMENT IN LOCAL SCHOOLS, ESPECIALLY THOSE WHICH SERVE HISTORICALLY UNDERREPRESENTED COMMUNITIES IN THESE FIELDS. THE DEVELOPMENT OF NEW MATERIALS AND PROCESSES BY TRIAL AND ERROR IS TIME-CONSUMING AND EXPENSIVE. INTEGRATED COMPUTATIONAL MATERIALS ENGINEERING IS A METHOD THAT OPTIMIZES MATERIALS FOR APPLICATIONS THROUGH THE INTERPLAY OF SIMULATION AND EXPERIMENTAL VALIDATION TO ACCELERATE INNOVATION. HAVING THE BEST POSSIBLE MICROSTRUCTURAL DATA IS CRUCIAL TO THIS PROCESS. THE ION MILL WILL BE USED TO CREATE CROSS-SECTIONS AND PLANAR SURFACES WITH MINIMAL DAMAGE TO PRESERVE NANOSCALE FEATURES AFTER VARIOUS MECHANICAL AND CHEMICAL PROCESSES TO ILLUMINATE CHEMISTRY-STRUCTURE-PROCESS-PROPERTY RELATIONSHIPS. THIS DATA WILL BE COMPARED TO COMPUTATIONAL PREDICTIONS INCORPORATING THE INTERNAL STATE VARIABLE APPROACH TO MULTISCALE MODELING. THE RESEARCH ENABLED WILL PAIR TOGETHER FACULTY WITH EXPERTISE IN COMPUTATIONAL AND EXPERIMENTAL ENGINEERING WITH LOCAL INDUSTRY AND INCLUDE INTERDISCIPLINARY WORK IN BIOMEDICAL APPLICATIONS WITH THE COLLEGE OF MEDICINE. THE ION MILL WILL BE USED SYNERGISTICALLY WITH LIBERTY UNIVERSITY?S WORLD-CLASS MICROSCOPY FACILITIES, INCLUDING A FIRST-OF-ITS-KIND IN-SITU HEATING AND MECHANICAL TESTING STAGE FOR USE IN THE ELECTRON MICROSCOPE. THIS PROJECT IS JOINTLY FUNDED BY THE MAJOR INSTRUMENTATION RESEARCH PROGRAM (MRI) AND THE DIVISION OF CIVIL, MECHANICAL AND MANUFACTURING INNOVATION (CMMI). THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.- SUBAWARDS ARE NOT PLANNED FOR THIS AWARD.

GRADUATE RESEARCH FELLOWSHIP PROGRAM (GRFP) -THE NATIONAL SCIENCE FOUNDATION (NSF) GRADUATE RESEARCH FELLOWSHIP PROGRAM (GRFP) IS A HIGHLY COMPETITIVE, FEDERAL FELLOWSHIP PROGRAM. GRFP HELPS ENSURE THE VITALITY AND DIVERSITY OF THE SCIENTIFIC AND ENGINEERING WORKFORCE OF THE UNITED STATES. THE PROGRAM RECOGNIZES AND SUPPORTS OUTSTANDING GRADUATE STUDENTS WHO ARE PURSUING RESEARCH-BASED MASTER'S AND DOCTORAL DEGREES IN SCIENCE, TECHNOLOGY, ENGINEERING, AND MATHEMATICS (STEM) AND IN STEM EDUCATION. THE GRFP PROVIDES THREE YEARS OF FINANCIAL SUPPORT FOR THE GRADUATE EDUCATION OF INDIVIDUALS WHO HAVE DEMONSTRATED THEIR POTENTIAL FOR SIGNIFICANT RESEARCH ACHIEVEMENTS IN STEM AND STEM EDUCATION. THIS AWARD SUPPORTS THE NSF GRADUATE FELLOWS PURSUING GRADUATE EDUCATION AT THIS GRFP INSTITUTION. THIS AWARD REFLECTS NSF'S STATUTORY MISSION AND HAS BEEN DEEMED WORTHY OF SUPPORT THROUGH EVALUATION USING THE FOUNDATION'S INTELLECTUAL MERIT AND BROADER IMPACTS REVIEW CRITERIA.

FY24 DEPARTMENT OF DEFENSE (DOD) CYBER SCHOLARSHIP PROGRAM (CYSP) AND DOD CYBER AND DIGITAL SERVICES ACADEMY (DCDSA) GRANTS: LIBERTY UNIVERSITY

FISCAL YEAR 2025 DEPARTMENT OF DEFENSE CHIEF INFORMATION OFFICER CYBER SERVICE ACADEMY SCHOLARSHIPS: LIBERTY UNIVERSITY

NETS: JUNO: COLLABORATIVE RESEARCH: LOCATION-BASED FORWARDING AND ID-BASED ROUTING (LORIF) FOR THE FUTURE INTERNET

NEW STIR GRANT "ADDRESSING THE STRENGTH-DUCTILITY TRADE-OFF USING AUTOMATED SURFACE NANOCRYSTALLIZATION"